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Home Other Building Blocks 2'-Deoxy-2'-fluorouridine

2'-Deoxy-2'-fluorouridine

CAS No.:
784-71-4
Catalog Number:
AG0035VT
Molecular Formula:
C9H11FN2O5
Molecular Weight:
246.1924
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$19
- +
5g
98%
In Stock USA
United States
$63
- +
10g
98%
In Stock USA
United States
$119
- +
25g
98%
In Stock USA
United States
$219
- +
100g
98%
In Stock USA
United States
$825
- +
Product Description
Catalog Number:
AG0035VT
Chemical Name:
2'-Deoxy-2'-fluorouridine
CAS Number:
784-71-4
Molecular Formula:
C9H11FN2O5
Molecular Weight:
246.1924
MDL Number:
MFCD01317293
IUPAC Name:
1-[(2R,3R,4R,5R)-3-fluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidine-2,4-dione
InChI:
InChI=1S/C9H11FN2O5/c10-6-7(15)4(3-13)17-8(6)12-2-1-5(14)11-9(12)16/h1-2,4,6-8,13,15H,3H2,(H,11,14,16)/t4-,6-,7-,8-/m1/s1
InChI Key:
UIYWFOZZIZEEKJ-XVFCMESISA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)F)n1ccc(=O)[nH]c1=O
UNII:
Y2YC903QW8
Properties
Complexity:
374  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
246.065g/mol
Formal Charge:
0
Heavy Atom Count:
17  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
246.194g/mol
Monoisotopic Mass:
246.065g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
99.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1  
Literature
Title Journal
Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides. Bioorganic & medicinal chemistry 20051215
Design, synthesis, and antiviral activity of 2'-deoxy-2'-fluoro-2'-C-methylcytidine, a potent inhibitor of hepatitis C virus replication. Journal of medicinal chemistry 20050825
Synthesis and anti-viral activity of a series of d- and l-2'-deoxy-2'-fluororibonucleosides in the subgenomic HCV replicon system. Bioorganic & medicinal chemistry 20050301
Recognition of an unnatural difluorophenyl nucleotide by uracil DNA glycosylase. Biochemistry 20041214
Distribution of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil in mice bearing colorectal cancer xenografts: rationale for therapeutic use and as a positron emission tomography probe for thymidylate synthase. Clinical cancer research : an official journal of the American Association for Cancer Research 20041001
Nucleosides. 123. Synthesis of antiviral nucleosides: 5-substituted 1-(2-deoxy-2-halogeno-beta-D-arabinofuranosyl)cytosines and -uracils. Some structure-activity relationships. Journal of medicinal chemistry 19830201
Properties