Synthesis and one-electron reduction characteristics of radiation-activated prodrugs possessing two 5-fluorodeoxyuridine units.

Bioorganic & medicinal chemistry 20120901

[Doxifluridine, medroxyprogesterone acetate and cyclophosphamide(DMpC)combination therapy found effective for case of chest wall recurrent breast cancer with bone and pleural metastases].

Gan to kagaku ryoho. Cancer & chemotherapy 20120801

Synthesis and study of cyclic pronucleotides of 5-fluoro-2'-deoxyuridine.

Bioorganic & medicinal chemistry letters 20120715

Efficacy of hepatic arterial infusion chemotherapy in advanced hepatocellular carcinoma.

World journal of gastroenterology 20120714

Attenuation of phosphorylation by deoxycytidine kinase is key to acquired gemcitabine resistance in a pancreatic cancer cell line: targeted proteomic and metabolomic analyses in PK9 cells.

Pharmaceutical research 20120701

The effect of chemotherapy or radiotherapy on thymidine phosphorylase and dihydropyrimidine dehydrogenase expression in cancer of the uterine cervix.

European journal of obstetrics, gynecology, and reproductive biology 20120701

A thymidylate synthase ternary complex-specific antibody, FTS, permits functional monitoring of fluoropyrimidines dosing.

Oncotarget 20120701

Pathway-based pharmacogenomics of gemcitabine pharmacokinetics in patients with solid tumors.

Pharmacogenomics 20120701

[Influence of interferon-α2a on thymidine phosphorylase expression and anticancer activity of 5'-deoxy-fluorouridine in human colon carcinoma cell lines LOVO and SW480].

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20120701

Neuronal caspase 2 activity and function requires RAIDD, but not PIDD.

The Biochemical journal 20120615

Lactobacillus probiotic protects intestinal epithelium from radiation injury in a TLR-2/cyclo-oxygenase-2-dependent manner.

Gut 20120601

Heterogeneous ribonucleoprotein K and thymidine phosphorylase are independent prognostic and therapeutic markers for oral squamous cell carcinoma.

Oral oncology 20120601

Green biosynthesis of floxuridine by immobilized microorganisms.

FEMS microbiology letters 20120601

Uracil-containing DNA in Drosophila: stability, stage-specific accumulation, and developmental involvement.

PLoS genetics 20120601

Hepatic arterial infusion in colorectal carcinoma: is anatomical targeting still relevant in an era of molecularly targeted therapy?

Biomedical papers of the Medical Faculty of the University Palacky, Olomouc, Czechoslovakia 20120601

Inhibition of EGFR phosphorylation in a panel of human breast cancer cells correlates with synergistic interactions between gefitinib and 5'-DFUR, the bioactive metabolite of Xeloda.

Breast cancer research and treatment 20120501

Biliary sclerosis after hepatic arterial infusion pump chemotherapy for patients with colorectal cancer liver metastasis: incidence, clinical features, and risk factors.

Annals of surgical oncology 20120501

Discovery of a novel class of potent human deoxyuridine triphosphatase inhibitors remarkably enhancing the antitumor activity of thymidylate synthase inhibitors.

Journal of medicinal chemistry 20120412

Synthesis and discovery of N-carbonylpyrrolidine- or N-sulfonylpyrrolidine-containing uracil derivatives as potent human deoxyuridine triphosphatase inhibitors.

Journal of medicinal chemistry 20120412

Chemotherapy-induced toxicity is highly heritable in Drosophila melanogaster.

Pharmacogenetics and genomics 20120401

Early postoperative intraperitoneal chemotherapy following cytoreductive surgery for appendiceal mucinous neoplasms with isolated peritoneal metastasis.

Diseases of the colon and rectum 20120401

The optimal selection of radiotherapy treatment for hepatocellular carcinoma.

Gut and liver 20120401

The feasibility of enzyme targeted activation for amino acid/dipeptide monoester prodrugs of floxuridine; cathepsin D as a potential targeted enzyme.

Molecules (Basel, Switzerland) 20120326

Delivery of floxuridine derivatives to cancer cells by water-soluble organometallic cages.

Bioconjugate chemistry 20120321

Significance of microsatellite instability (MSI) for colorectal cancer following adjuvant therapy with doxifluridine.

Medical oncology (Northwood, London, England) 20120301

Hepatic arterial infusion and systemic chemotherapy after multiple metastasectomy in patients with colorectal carcinoma metastatic to the liver: a North Central Cancer Treatment Group (NCCTG) phase II study, 92-46-52.

Clinical colorectal cancer 20120301

Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease.

Cell death and differentiation 20120301

Evaluation of drugs with specific organ toxicities in organ-specific cell lines.

Toxicological sciences : an official journal of the Society of Toxicology 20120301

Inhibition of dUTPase induces synthetic lethality with thymidylate synthase-targeted therapies in non-small cell lung cancer.

Molecular cancer therapeutics 20120301

Reliability of tumor primary cultures as a model for drug response prediction: expression profiles comparison of tissues versus primary cultures from colorectal cancer patients.

Journal of cancer research and clinical oncology 20120301

Reductive activation of 5-fluorodeoxyuridine prodrug possessing azide methyl group by hypoxic X-irradiation.

Bioorganic & medicinal chemistry letters 20120215

Postoperative intraperitoneal 5-fluoro-2'-deoxyuridine added to chemoradiation in patients curatively resected (R0) for locally advanced gastric and gastroesophageal junction adenocarcinoma.

Annals of surgical oncology 20120201

Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.

Glia 20120201

[Population pharmacokinetics of gemcitabine applied to personalize the dosage used in cancer patients].

Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20120101

Fluorodeoxyuridine affects the identification of metabolic responses to daf-2 status in Caenorhabditis elegans.

Mechanisms of ageing and development 20120101

Pre and post synaptic NMDA effects targeting Purkinje cells in the mouse cerebellar cortex.

PloS one 20120101

Tasco®: a product of Ascophyllum nodosum enhances immune response of Caenorhabditis elegans against Pseudomonas aeruginosa infection.

Marine drugs 20120101

Identification of cancer cell-line origins using fluorescence image-based phenomic screening.

PloS one 20120101

Protease-activated drug development.

Theranostics 20120101

Molecular prognostic prediction for locally advanced nasopharyngeal carcinoma by support vector machine integrated approach.

PloS one 20120101

Control of intestinal bacterial proliferation in regulation of lifespan in Caenorhabditis elegans.

BMC microbiology 20120101

Characterization of the proteostasis roles of glycerol accumulation, protein degradation and protein synthesis during osmotic stress in C. elegans.

PloS one 20120101

Loss of glutathione homeostasis associated with neuronal senescence facilitates TRPM2 channel activation in cultured hippocampal pyramidal neurons.

Molecular brain 20120101

The Nematode Caenorhabditis elegans, Stress and Aging: Identifying the Complex Interplay of Genetic Pathways Following the Treatment with Humic Substances.

Frontiers in genetics 20120101

Effect of angiogenesis inhibitor bevacizumab on survival in patients with cancer: a meta-analysis of the published literature.

PloS one 20120101

Overexpression of the orotate phosphoribosyl-transferase gene enhances the effect of 5-Fluorouracil in head and neck squamous cell carcinoma in vitro.

Journal of oncology 20120101

Modulation of experimental herpes encephalitis-associated neurotoxicity through sulforaphane treatment.

PloS one 20120101

NT2 derived neuronal and astrocytic network signalling.

PloS one 20120101

18F-FLT and 125I-IdUrd uptake increase in human tumour cell lines induced by the thymidylate synthase inhibitor FdUrd.

Nuklearmedizin. Nuclear medicine 20120101

Combination drug delivery approaches in metastatic breast cancer.

Journal of drug delivery 20120101

Divergent modulation of neuronal differentiation by caspase-2 and -9.

PloS one 20120101

Stereotactic body radiation therapy for liver metastases from colorectal cancer: analysis of safety, feasibility, and early outcomes.

Frontiers in oncology 20120101

Pan-pathway based interaction profiling of FDA-approved nucleoside and nucleobase analogs with enzymes of the human nucleotide metabolism.

PloS one 20120101

An unusual presentation of tumor lysis syndrome in a patient with advanced gastric adenocarcinoma: case report and literature review.

Case reports in medicine 20120101

Regional susceptibility to TNF-α induction of murine brain inflammation via classical IKK/NF-κB signalling.

PloS one 20120101

The effect of locoregional transarterial infusion chemotherapy on liver metastasis after gastric cancer resection.

The Journal of international medical research 20120101

Selection of suitable prodrug candidates for in vivo studies via in vitro studies; the correlation of prodrug stability in between cell culture homogenates and human tissue homogenates.

Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101

Hepatic arterial infusion with irinotecan, oxaliplatin, and floxuridine plus systemic chemotherapy as first-line treatment of unresectable liver metastases from colorectal cancer.

Onkologie 20120101

Impact of sublethal levels of environmental pollutants found in sewage sludge on a novel Caenorhabditis elegans model biosensor.

PloS one 20120101

Cytostatic activity of the duplex drug linking 2'-deoxy-5-fluorouridine (5FdU) with 3'-C-ethynylcytidine (ECyd) against gastric adenocarcinoma cell lines.

Investigational new drugs 20111201

Clinical significance of microsatellite instability for stage II or III colorectal cancer following adjuvant therapy with doxifluridine.

Medical oncology (Northwood, London, England) 20111201

Comparison of adjuvant systemic chemotherapy with or without hepatic arterial infusional chemotherapy after hepatic resection for metastatic colorectal cancer.

Annals of surgery 20111201

Determination of the phosphorylated metabolites of gemcitabine and of difluorodeoxyuridine by LCMSMS.

Nucleosides, nucleotides & nucleic acids 20111201

A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor.

PLoS pathogens 20111201

Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).

PLoS computational biology 20111201

Weekly paclitaxel in combination with doxifluridine for peritoneally disseminated gastric cancer with malignant ascites.

Anticancer research 20111201

A novel method for quantification of gemcitabine and its metabolites 2',2'-difluorodeoxyuridine and gemcitabine triphosphate in tumour tissue by LC-MS/MS: comparison with (19)F NMR spectroscopy.

Cancer chemotherapy and pharmacology 20111101

A novel RING finger protein, Znf179, modulates cell cycle exit and neuronal differentiation of P19 embryonal carcinoma cells.

Cell death and differentiation 20111101

The deaminated metabolite of gemcitabine, 2',2'-difluorodeoxyuridine, modulates the rate of gemcitabine transport and intracellular phosphorylation via deoxycytidine kinase.

Drug metabolism and disposition: the biological fate of chemicals 20111101

Phosphoramidate ProTides of the anticancer agent FUDR successfully deliver the preformed bioactive monophosphate in cells and confer advantage over the parent nucleoside.

Journal of medicinal chemistry 20111027

Novel anticancer polymeric conjugates of activated nucleoside analogues.

Bioconjugate chemistry 20111019

Increased life span from overexpression of superoxide dismutase in Caenorhabditis elegans is not caused by decreased oxidative damage.

Free radical biology & medicine 20111015

Potential of amino acid/dipeptide monoester prodrugs of floxuridine in facilitating enhanced delivery of active drug to interior sites of tumors: a two-tier monolayer in vitro study.

Pharmaceutical research 20111001

Second-line chemotherapy with paclitaxel and doxifluridine after failure of S-1 in elderly patients with unresectable advanced or recurrent gastric cancer.

Journal of cancer research and clinical oncology 20111001

FUdR causes a twofold increase in the lifespan of the mitochondrial mutant gas-1.

Mechanisms of ageing and development 20111001

Chemotherapy for the conversion of unresectable colorectal cancer liver metastases to resection.

Critical reviews in oncology/hematology 20110901

The cytostatic activity of NUC-3073, a phosphoramidate prodrug of 5-fluoro-2'-deoxyuridine, is independent of activation by thymidine kinase and insensitive to degradation by phosphorolytic enzymes.

Biochemical pharmacology 20110901

Combining small interfering RNAs targeting thymidylate synthase and thymidine kinase 1 or 2 sensitizes human tumor cells to 5-fluorodeoxyuridine and pemetrexed.

The Journal of pharmacology and experimental therapeutics 20110901

Antiangiogenic therapy for primary liver cancer: correlation of changes in dynamic contrast-enhanced magnetic resonance imaging with tissue hypoxia markers and clinical response.

Annals of surgical oncology 20110801

Metronomic doxifluridine chemotherapy combined with the anti-angiogenic agent TNP-470 inhibits the growth of human uterine carcinosarcoma xenografts.

Cancer science 20110801

Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies.

Pharmacogenetics and genomics 20110801

Poly(ADP-Ribose) polymerase inhibition synergizes with 5-fluorodeoxyuridine but not 5-fluorouracil in ovarian cancer cells.

Cancer research 20110715

Design, synthesis and biological evaluation of 2'-deoxy-2',2'-difluoro-5-halouridine phosphoramidate ProTides.

Bioorganic & medicinal chemistry 20110715

Difluorodeoxyuridine plasma concentrations after low-dose gemcitabine during chemoradiation in head and neck cancer patients.

Cancer chemotherapy and pharmacology 20110701

Selective intra-arterial chemotherapy with floxuridine as second- or third-line approach in patients with unresectable colorectal liver metastases.

Annals of surgical oncology 20110701

Salvage combination chemotherapy with floxuridine, dactinomycin, etoposide, and vincristine (FAEV) for patients with relapsed/chemoresistant gestational trophoblastic neoplasia.

Annals of oncology : official journal of the European Society for Medical Oncology 20110701

Mode of action of trifluorothymidine (TFT) against DNA replication and repair enzymes.

International journal of oncology 20110701

Treating primary liver cancer with hepatic arterial infusion of floxuridine and dexamethasone: does the addition of systemic bevacizumab improve results?

Oncology 20110701

Disruption of the ATP-binding cassette B7 (ABTM-1/ABCB7) induces oxidative stress and premature cell death in Caenorhabditis elegans.

The Journal of biological chemistry 20110617

Stabilization of thymidine phosphorylase from Escherichia coli by immobilization and post immobilization techniques.

Enzyme and microbial technology 20110610

Antiproliferative activity, mechanism of action and oral antitumor activity of CP-4126, a fatty acid derivative of gemcitabine, in in vitro and in vivo tumor models.

Investigational new drugs 20110601

N⁴-[Alkyl-(hydroxyphosphono)phosphonate]-cytidine-new drugs covalently linking antimetabolites (5-FdU, araU or AZT) with bone-targeting bisphosphonates (alendronate or pamidronate).

Bioorganic & medicinal chemistry 20110601

Cellular response to efficient dUTPase RNAi silencing in stable HeLa cell lines perturbs expression levels of genes involved in thymidylate metabolism.

Nucleosides, nucleotides & nucleic acids 20110601

[Improved sensitivity of gastric carcinoma cells to fluorouracil-related drugs by transfection of thymidine phosphorylase gene].

Zhonghua bing li xue za zhi = Chinese journal of pathology 20110501

The achievement of mass balance by simultaneous quantification of floxuridine prodrug, floxuridine, 5-fluorouracil, 5-dihydrouracil, α-fluoro-β-ureidopropionate, α-fluoro-β-alanine using LC-MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415

Cellular pharmacology of multi- and duplex drugs consisting of ethynylcytidine and 5-fluoro-2'-deoxyuridine.

Investigational new drugs 20110401

Increase of [(18)F]FLT tumor uptake in vivo mediated by FdUrd: toward improving cell proliferation positron emission tomography.

Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20110401

A phase II study of neoadjuvant and adjuvant chemotherapy with 5-fluorodeoxyuridine, leucovorin, oxaliplatin and docetaxel in the treatment of previously untreated advanced esophageal adenocarcinoma.

Japanese journal of clinical oncology 20110401

Effect of its deaminated metabolite, 2',2'-difluorodeoxyuridine, on the transport and toxicity of gemcitabine in HeLa cells.

Biochemical pharmacology 20110401

Synthesis and biological evaluation of unsaturated keto and exomethylene D-arabinopyranonucleoside analogs: novel 5-fluorouracil analogs that target thymidylate synthase.

European journal of medicinal chemistry 20110401

[A case of gastric cancer with lung, Virchow and para-aortic lymph node metastases treated successfully using PTX/5'-DFUR].

Gan to kagaku ryoho. Cancer & chemotherapy 20110401

PDP-1 links the TGF-β and IIS pathways to regulate longevity, development, and metabolism.

PLoS genetics 20110401

Combinatorial pharmacologic effects of gemcitabine and its metabolite dFdU.

ChemMedChem 20110307

Development and validation of a prediction model for the risk of developing febrile neutropenia in the first cycle of chemotherapy among elderly patients with breast, lung, colorectal, and prostate cancer.

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20110301

Plasma disposition of capecitabine and its metabolites 5'DFCR and 5'DFUR in a standard and dose-intensified monotherapy regimen.

Cancer chemotherapy and pharmacology 20110301

Randomized phase II trial of adjuvant hepatic arterial infusion and systemic chemotherapy with or without bevacizumab in patients with resected hepatic metastases from colorectal cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110301

Efficacy and safety of hepatic arterial infusion of fluorouracil with leucovorin as salvage treatment for refractory liver metastases from colorectal cancer.

The Korean journal of internal medicine 20110301

Effect of the thymidylate synthase inhibitors on dUTP and TTP pool levels and the activities of DNA repair glycosylases on uracil and 5-fluorouracil in DNA.

Biochemistry 20110208

Nearly monodispersed core-shell structural Fe3O4@DFUR-LDH submicro particles for magnetically controlled drug delivery and release.

Chemical communications (Cambridge, England) 20110121

Mumijo traditional medicine: fossil deposits from antarctica (chemical composition and beneficial bioactivity).

Evidence-based complementary and alternative medicine : eCAM 20110101

Drug efflux transporter multidrug resistance-associated protein 5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil.

Drug metabolism and disposition: the biological fate of chemicals 20110101

Effect of small interfering RNA 3'-end overhangs on chemosensitivity to thymidylate synthase inhibitors.

Silence 20110101

A phase II study of weekly paclitaxel and doxifluridine combination chemotherapy for advanced/recurrent gastric cancer.

Anticancer research 20110101

Phase i study evaluating the treatment of patients with hepatocellular carcinoma (HCC) with carbon ion radiotherapy: the PROMETHEUS-01 trial.

BMC cancer 20110101

Remodeling of the metabolome during early frog development.

PloS one 20110101

Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells.

PloS one 20110101

Measuring Caenorhabditis elegans life span in 96 well microtiter plates.

Journal of visualized experiments : JoVE 20110101

Lentiviral vector-mediated stable expression of sTNFR-Fc in human macrophage and neuronal cells as a potential therapy for neuroAIDS.

Journal of neuroinflammation 20110101

DNA damage during G2 phase does not affect cell cycle progression of the green alga Scenedesmus quadricauda.

PloS one 20110101

Volumetric intensity-modulated Arc (RapidArc) therapy for primary hepatocellular carcinoma: comparison with intensity-modulated radiotherapy and 3-D conformal radiotherapy.

Radiation oncology (London, England) 20110101

The interplay between protein L-isoaspartyl methyltransferase activity and insulin-like signaling to extend lifespan in Caenorhabditis elegans.

PloS one 20110101

Resveratrol inhibits Cdk5 activity through regulation of p35 expression.

Molecular pain 20110101

A case of advanced hepatocellular carcinoma with portal vein tumor thrombus refractory to epirubicin that showed marked decrease in tumor markers after transcatheter arterial infusion with miriplatin.

Case reports in oncology 20110101

The MEK-ERK pathway negatively regulates bim expression through the 3' UTR in sympathetic neurons.

BMC neuroscience 20110101

Differences in sensitivity to DNA-damaging Agents between XRCC4- and Artemis-deficient human cells.

Journal of radiation research 20110101

Functional modifications of acid-sensing ion channels by ligand-gated chloride channels.

PloS one 20110101

Catheterization and embolization of a replaced left hepatic artery via the right gastric artery through the anastomosis: a case report.

Journal of medical case reports 20110101

Enzymatic synthesis of long double-stranded DNA labeled with haloderivatives of nucleobases in a precisely pre-determined sequence.

BMC biochemistry 20110101

Prognostic significance of miR-181b and miR-21 in gastric cancer patients treated with S-1/Oxaliplatin or Doxifluridine/Oxaliplatin.

PloS one 20110101

NF-kappaB activation within macrophages leads to an anti-tumor phenotype in a mammary tumor lung metastasis model.

Breast cancer research : BCR 20110101

Global analysis of gene expression in NGF-deprived sympathetic neurons identifies molecular pathways associated with cell death.

BMC genomics 20110101

Pathogenesis and phylogenetic analyses of canine distemper virus strain ZJ7 isolate from domestic dogs in China.

Virology journal 20110101

Phosphorylation of 5'-deoxy-5-fluorouridine with inorganic phosphorylating agents.

Chemical & pharmaceutical bulletin 20110101

The MDT-15 subunit of mediator interacts with dietary restriction to modulate longevity and fluoranthene toxicity in Caenorhabditis elegans.

PloS one 20110101

Tasco(®), a product of Ascophyllum nodosum, imparts thermal stress tolerance in Caenorhabditis elegans.

Marine drugs 20110101

Skull base metastases from a malignant solitary fibrous tumor of the liver. A case report and literature review.

Diagnostic pathology 20110101

Checkpoint signaling, base excision repair, and PARP promote survival of colon cancer cells treated with 5-fluorodeoxyuridine but not 5-fluorouracil.

PloS one 20110101

Yttrium-90 radioembolization for colorectal cancer liver metastases: a single institution experience.

International journal of surgical oncology 20110101

Minimally invasive evaluation and treatment of colorectal liver metastases.

International journal of surgical oncology 20110101

Optimizing Liposomal Cisplatin Efficacy through Membrane Composition Manipulations.

Chemotherapy research and practice 20110101

Integration of Principles of Systems Biology and Radiation Biology: Toward Development of in silico Models to Optimize IUdR-Mediated Radiosensitization of DNA Mismatch Repair Deficient (Damage Tolerant) Human Cancers.

Frontiers in oncology 20110101

A predictive ligand-based Bayesian model for human drug-induced liver injury.

Drug metabolism and disposition: the biological fate of chemicals 20101201

Use of nanoscale delivery systems to maintain synergistic drug ratios in vivo.

Expert opinion on drug delivery 20101201

Genome-wide mRNA and microRNA profiling of the NCI 60 cell-line screen and comparison of FdUMP[10] with fluorouracil, floxuridine, and topoisomerase 1 poisons.

Molecular cancer therapeutics 20101201

Cytotoxicity and antileukaemic activity of new duplexes linking 3-C-ethynylcytidine and 5-fluorodeoxyuridine.

Anticancer research 20101201

Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii.

PLoS biology 20101201

Antiviral activity of 2,3'-anhydro and related pyrimidine nucleosides against hepatitis B virus.

Bioorganic & medicinal chemistry letters 20101115

Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase.

British journal of cancer 20101101

Bifunctional conjugates comprising β-cyclodextrin, polyethylenimine, and 5-fluoro-2'- deoxyuridine for drug delivery and gene transfer.

Bioconjugate chemistry 20101020

Controlled removal of a nonviral episomal vector from transfected cells.

Gene 20101015

Antiviral activity of various 1-(2'-deoxy-β-D-lyxofuranosyl), 1-(2'-fluoro-β-D-xylofuranosyl), 1-(3'-fluoro-β-D-arabinofuranosyl), and 2'-fluoro-2',3'-didehydro-2',3'-dideoxyribose pyrimidine nucleoside analogues against duck hepatitis B virus (DHBV) and human hepatitis B virus (HBV) replication.

Journal of medicinal chemistry 20101014

Increased anticoagulant activity of warfarin used in combination with doxifluridine.

Cancer chemotherapy and pharmacology 20101001

Adjuvant oxaliplatin- or irinotecan-containing chemotherapy improves overall survival following resection of metachronous colorectal liver metastases.

International journal of colorectal disease 20101001

Design, synthesis, and anticancer activities of novel perfluoroalkyltriazole-appended 2'-deoxyuridines.

Bioorganic & medicinal chemistry letters 20101001

An unusual case of capecitabine hyperpigmentation: Is hyperpigmentation a part of hand-foot syndrome or a separate entity?

Indian journal of pharmacology 20101001

Monitoring of duplex and triplex formation by 19F NMR using oligodeoxynucleotides possessing 5-fluorodeoxyuridine unit as 19F signal transmitter.

Bioorganic & medicinal chemistry 20100915

Highly regioselective galactosylation of floxuridine catalyzed by beta-galactosidase from bovine liver.

Biotechnology letters 20100901

Multidrug nanoparticles based on novel random copolymer containing cytarabine and fluorodeoxyuridine.

Journal of colloid and interface science 20100901

[Bi-weekly docetaxel and doxifluridine combination therapy in pretreated patients with unresectable and/or advanced gastric cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20100901

Epidermal growth factor receptor mutation and diverse tumors: case report and concise literature review.

Molecular oncology 20100801

Population pharmacokinetics of gemcitabine and its metabolite in Japanese cancer patients: impact of genetic polymorphisms.

Clinical pharmacokinetics 20100801

The relationship between clinicopathological factors and the reduction of pyrimidine nucleoside phosphorylase activity after preoperative administration of 5'-deoxy-5-fluorouridine.

Anticancer research 20100801

DNA instability at chromosomal fragile sites in cancer.

Current genomics 20100801

Lactosaminated human albumin, a hepatotropic carrier of drugs.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100711

PfNT2, a permease of the equilibrative nucleoside transporter family in the endoplasmic reticulum of Plasmodium falciparum.

The Journal of biological chemistry 20100702

Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole.

Cellular microbiology 20100701

Epstein-Barr virus latent membrane protein 1 induces the chemotherapeutic target, thymidine phosphorylase, via NF-kappaB and p38 MAPK pathways.

Cellular signalling 20100701

Plasma disposition of capecitabine (CCB) and its metabolites 5'-deoxy-5-fluorocytidine (5'-DFCR) and 5'-deoxy-5-fluorouracil (5'-DFUR) with two different capecitabine/oxaliplatin dosage regimens.

International journal of clinical pharmacology and therapeutics 20100701

Hepatic arterial infusion with oxaliplatin, irinotecan and doxifluridine for unresectable liver metastases of colorectal cancer.

Anticancer research 20100701

New trends in nucleoside biotechnology.

Acta naturae 20100701

Effects of structural differences between radioiodine-labeled 1-(2'-fluoro-2'-deoxy-D-arabinofuranosyl)-5-iodouracil (FIAU) and 1-(2'-fluoro-2'-deoxy-d-ribofuranosyl)-5-iodouracil (FIRU) on HSV1-TK reporter gene imaging.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20100601

Gemcitabine-loaded PEGylated unilamellar liposomes vs GEMZAR: biodistribution, pharmacokinetic features and in vivo antitumor activity.

Journal of controlled release : official journal of the Controlled Release Society 20100601

Pharmacokinetics of gemcitabine in non-small-cell lung cancer patients: impact of the 79A>C cytidine deaminase polymorphism.

European journal of clinical pharmacology 20100601

Pasteurella multocida thymidine kinase 1 efficiently activates pyrimidine nucleoside analogs.

Nucleosides, nucleotides & nucleic acids 20100601

Toxicity of perfluorinated carboxylic acids for aquatic organisms.

Interdisciplinary toxicology 20100601

Prodrug activation by Cryptosporidium thymidine kinase.

The Journal of biological chemistry 20100521

Protein expression profiles of necrosis and apoptosis induced by 5-fluoro-2'-deoxyuridine in mouse cancer cells.

Journal of proteome research 20100507

The role of local protein synthesis and degradation in axon regeneration.

Experimental neurology 20100501

The role of the polyamine catabolic enzymes SSAT and SMO in the synergistic effects of standard chemotherapeutic agents with a polyamine analogue in human breast cancer cell lines.

Cancer chemotherapy and pharmacology 20100501

The use of FUdR can cause prolonged longevity in mutant nematodes.

Mechanisms of ageing and development 20100501

Selective targeting of 2'-deoxy-5-fluorouridine to urokinase positive malignant cells in vitro.

Bioorganic & medicinal chemistry letters 20100501

In defense of hepatic arterial infusion for hepatic metastases of colorectal cancer.

Journal of the National Comprehensive Cancer Network : JNCCN 20100501

Glycal formation in crystals of uridine phosphorylase.

Biochemistry 20100427

A new, validated HPLC-MS/MS method for the simultaneous determination of the anti-cancer agent capecitabine and its metabolites: 5'-deoxy-5-fluorocytidine, 5'-deoxy-5-fluorouridine, 5-fluorouracil and 5-fluorodihydrouracil, in human plasma.

Biomedical chromatography : BMC 20100401

Identification of peptide ligands for targeting to the blood-brain barrier.

Pharmaceutical research 20100401

Phosphorylation of the conserved transcription factor ATF-7 by PMK-1 p38 MAPK regulates innate immunity in Caenorhabditis elegans.

PLoS genetics 20100401

Phase I study of irinotecan and doxifluridine for metastatic colorectal cancer focusing on the UGT1A1*28 polymorphism.

Cancer science 20100301

Azidothymidine enhances fluorodeoxyuridine-mediated radiosensitization.

International journal of radiation oncology, biology, physics 20100301

Role of RecA and the SOS response in thymineless death in Escherichia coli.

PLoS genetics 20100301

Alternating systemic and hepatic artery infusion therapy for resected liver metastases from colorectal cancer: a North Central Cancer Treatment Group (NCCTG)/ National Surgical Adjuvant Breast and Bowel Project (NSABP) phase II intergroup trial, N9945/CI-66.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210

Comparison of average, scaled average, and population bioequivalence methods for assessment of highly variable drugs: an experience with doxifluridine in beagle dogs.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100131

Differential expression of a novel gene BRE (TNFRSF1A modulator/BRCC45) in response to stress and biological signals.

Molecular biology reports 20100101

Synthesis and antitumor activity of novel 2',3'-dideoxy-2',3'-diethanethionucleosides bearing 1,2,3-triazole residues.

Bioorganic & medicinal chemistry letters 20100101

The role of emerging and investigational therapies for metastatic brain tumors: a systematic review and evidence-based clinical practice guideline of selected topics.

Journal of neuro-oncology 20100101

Liposome formulations of hydrophobic drugs.

Methods in molecular biology (Clifton, N.J.) 20100101

Therapeutic usefulness of postoperative adjuvant chemotherapy with Tegafur-Uracil (UFT) in patients with breast cancer: focus on the results of clinical studies in Japan.

The oncologist 20100101

Endogenous Nmnat2 is an essential survival factor for maintenance of healthy axons.

PLoS biology 20100101

Allyl isothiocyanate that induces GST and UGT expression confers oxidative stress resistance on C. elegans, as demonstrated by nematode biosensor.

PloS one 20100101

Angiogenic factors stimulate growth of adult neural stem cells.

PloS one 20100101

Screening mammography use and chemotherapy among female stage II colon cancer patients: a retrospective cohort study.

BMC health services research 20100101

A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax.

Cancer cell international 20100101

Biological impact of geometric uncertainties: what margin is needed for intra-hepatic tumors?

Radiation oncology (London, England) 20100101

Herpes simplex virus induces neural oxidative damage via microglial cell Toll-like receptor-2.

Journal of neuroinflammation 20100101

Thymidylate synthase mRNA expression does not predict resistance to floxuridine in a choriocarcinoma cell line.

The Journal of reproductive medicine 20100101

C. elegans germline-deficient mutants respond to pathogen infection using shared and distinct mechanisms.

PloS one 20100101

Scope of nanotechnology in ovarian cancer therapeutics.

Journal of ovarian research 20100101

Inhibiting heat-shock protein 90 reverses sensory hypoalgesia in diabetic mice.

ASN neuro 20100101

Analysis of the thymidylate synthase gene structure in colorectal cancer patients and its possible relation with the 5-Fluorouracil drug response.

Journal of nucleic acids 20100101

Prospective evaluation of microscopic extension using whole-mount preparation in patients with hepatocellular carcinoma: Definition of clinical target volume for radiotherapy.

Radiation oncology (London, England) 20100101

Apoptosis-associated microRNAs are modulated in mouse, rat and human neural differentiation.

BMC genomics 20100101

Clostridium perfringens epsilon toxin targets granule cells in the mouse cerebellum and stimulates glutamate release.

PloS one 20100101

A simplified technique of percutaneous hepatic artery port-catheter insertion for the treatment of advanced hepatocellular carcinoma with portal vein invasion.

Korean journal of radiology 20100101

Comparison of simple and complex liver intensity modulated radiotherapy.

Radiation oncology (London, England) 20100101

Simple and rapid enzymatic method for the synthesis of single-strand oligonucleotides containing trifluorothymidine.

Nucleosides, nucleotides & nucleic acids 20100101

Advances in the field of nanooncology.

BMC medicine 20100101

Nanomedicine formulations for combination therapies.

Nano reviews 20100101

Genotyping and infection rate of GBV-C among Iranian HCV- infected patients.

Hepatitis monthly 20100101

Molecularly evolved thymidylate synthase inhibits 5-fluorodeoxyuridine toxicity in human hematopoietic cells.

Human gene therapy 20091201

Hypoxia and the hypoxic response pathway protect against pore-forming toxins in C. elegans.

PLoS pathogens 20091201

[A long term survivor of advanced gastric cancer treated with multi-drug combination chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20091101

[Establishment of floxuridine-resistant JeG-3 subline and the role of thymidylate synthetase mRNA expression in chem-resistant-prediction.].

Zhonghua fu chan ke za zhi 20091101

Challenge and hope in radiotherapy of hepatocellular carcinoma.

Yonsei medical journal 20091031

Selective internal radiation therapy for liver metastases from colorectal cancer.

The Cochrane database of systematic reviews 20091007

Postoperative chemotherapy after neoadjuvant chemoradiation and surgery for rectal cancer: is it essential for patients with ypT0-2N0?

Journal of surgical oncology 20091001

Peroxisome proliferator-activated receptor gamma coactivator-1alpha enhances antiproliferative activity of 5'-deoxy-5-fluorouridine in cancer cells through induction of uridine phosphorylase.

Molecular pharmacology 20091001

Simultaneous quantification of 5-FU, 5-FUrd, 5-FdUrd, 5-FdUMP, dUMP and TMP in cultured cell models by LC-MS/MS.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091001

Dose-response relationships of rat fetal skeleton variations: Relevance for risk assessment.

Environmental research 20091001

Synthesis and in vitro activities of new anticancer duplex drugs linking 2'-deoxy-5-fluorouridine (5-FdU) with 3'-C-ethynylcytidine (ECyd) via a phosphodiester bonding.

Bioorganic & medicinal chemistry 20091001

Induction-concurrent chemoradiotherapy versus induction chemotherapy and radiotherapy for locoregionally advanced nasopharyngeal carcinoma.

Ai zheng = Aizheng = Chinese journal of cancer 20091001

Hepatic arterial infusion for unresectable colorectal liver metastases combined or not with systemic chemotherapy.

Anticancer research 20091001

Combination therapy by trastuzumab with 5'-deoxy-5-fluorouridine and cyclophosphamide in patients with metastatic breast cancer.

The Tokai journal of experimental and clinical medicine 20090920

Regional chemotherapy for unresectable primary liver cancer: results of a phase II clinical trial and assessment of DCE-MRI as a biomarker of survival.

Annals of oncology : official journal of the European Society for Medical Oncology 20090901

Metastasis of gestational trophoblastic neoplasia to the spinal canal: a case report.

The Journal of reproductive medicine 20090901

Unexpected reversal of the regioselectivity in Thermomyces lanuginosus lipase-catalyzed acylation of floxuridine.

Biotechnology letters 20090801

Conversion to resectability using hepatic artery infusion plus systemic chemotherapy for the treatment of unresectable liver metastases from colorectal carcinoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090720

Substrate specificity of lipase from Burkholderia cepacia in the synthesis of 3'-arylaliphatic acid esters of floxuridine.

Journal of biotechnology 20090715

Development of a sensitive and selective LC-MS/MS method for simultaneous determination of gemcitabine and 2,2-difluoro-2-deoxyuridine in human plasma.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715

Fluoropyrimidine-HAI (hepatic arterial infusion) versus systemic chemotherapy (SCT) for unresectable liver metastases from colorectal cancer.

The Cochrane database of systematic reviews 20090708

Phase I trial of adjuvant hepatic arterial infusion (HAI) with floxuridine (FUDR) and dexamethasone plus systemic oxaliplatin, 5-fluorouracil and leucovorin in patients with resected liver metastases from colorectal cancer.

Annals of oncology : official journal of the European Society for Medical Oncology 20090701

Synchronous colorectal liver metastases: triumph of prospective randomized trials over observational bias leads to paradigm shift.

Annals of surgical oncology 20090701

Analysis of factors associated with outcome in patients undergoing isolated hepatic perfusion for unresectable liver metastases from colorectal center.

Annals of surgical oncology 20090701

Mass flows of X-ray contrast media and cytostatics in hospital wastewater.

Environmental science & technology 20090701

Impairment of APE1 function enhances cellular sensitivity to clinically relevant alkylators and antimetabolites.

Molecular cancer research : MCR 20090601

Ring-opening polymerization of epsilon-caprolactone initiated by the antitumor agent doxifluridine.

Acta biomaterialia 20090501

The role of floxuridine in metastatic liver disease.

Molecular cancer therapeutics 20090501

[Complete response obtained with first-line therapy as S-1, followed by second-line 5'-DFUR plus paclitaxel therapy in a patient with multiple liver and lymph node metastases from gastric cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20090501

HIF-1 modulates dietary restriction-mediated lifespan extension via IRE-1 in Caenorhabditis elegans.

PLoS genetics 20090501

Retention studies of 2'-2'-difluorodeoxycytidine and 2'-2'-difluorodeoxyuridine nucleosides and nucleotides on porous graphitic carbon: development of a liquid chromatography-tandem mass spectrometry method.

Journal of chromatography. A 20090410

Two-stage hepatectomy (R0) with portal vein ligation--towards curing patients with extended bilobular colorectal liver metastases.

International journal of colorectal disease 20090401

Base excision by thymine DNA glycosylase mediates DNA-directed cytotoxicity of 5-fluorouracil.

PLoS biology 20090401

Fluorescent in-situ hybridization of cattle and sheep chromosomes with cloned human fragile-X DNA.

Molecular biology reports 20090301

A human protein interaction network shows conservation of aging processes between human and invertebrate species.

PLoS genetics 20090301

Challenge of high polarity and low concentrations in analysis of cytostatics and metabolites in wastewater by hydrophilic interaction chromatography/tandem mass spectrometry.

Journal of chromatography. A 20090213

Reduction in ovulation or male sex phenotype increases long-term anoxia survival in a daf-16-independent manner in Caenorhabditis elegans.

Physiological genomics 20090201

Potential and future strategies for radiotherapy in hepatocellular carcinoma.

Liver international : official journal of the International Association for the Study of the Liver 20090201

Safety, pharmacokinetics, and efficacy of CPX-1 liposome injection in patients with advanced solid tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research 20090115

Efficient regioselective synthesis of 3'-O-crotonylfloxuridine catalysed by Pseudomonas cepacia lipase.

Biotechnology and applied biochemistry 20090101

Gemcitabine uptake in glioblastoma multiforme: potential as a radiosensitizer.

Annals of oncology : official journal of the European Society for Medical Oncology 20090101

Regulation of human dUTPase gene expression and p53-mediated transcriptional repression in response to oxaliplatin-induced DNA damage.

Nucleic acids research 20090101

Patterns of chemotherapy-induced hepatic injury and their implications for patients undergoing liver resection for colorectal liver metastases.

Journal of hepato-biliary-pancreatic surgery 20090101

[A randomized controlled trial of postoperative adjuvant chemotherapy for colorectal cancer-optimal duration of the treatment].

Gan to kagaku ryoho. Cancer & chemotherapy 20090101

[A case of complete response for advanced gastric cancer with liver metastasis treated with combination chemotherapy of weekly paclitaxel and doxifluridine].

Gan to kagaku ryoho. Cancer & chemotherapy 20090101

Optimizing dietary restriction for genetic epistasis analysis and gene discovery in C. elegans.

PloS one 20090101

Genome-scale identification of Caenorhabditis elegans regulatory elements by tiling-array mapping of DNase I hypersensitive sites.

BMC genomics 20090101

[Preparation of floxuridine loaded polycation and its antitumor activity].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20090101

Pharmacokinetics of gemcitabine at fixed-dose rate infusion in patients with normal and impaired hepatic function.

Clinical pharmacokinetics 20090101

Accumulation and processing of a recombinant protein designed as a cleavable fusion to the endogenous Rubisco LSU protein in Chlamydomonas chloroplast.

BMC biotechnology 20090101

Whole genome sequencing of a natural recombinant Toxoplasma gondii strain reveals chromosome sorting and local allelic variants.

Genome biology 20090101

Identification and characterization of inhibitors of human apurinic/apyrimidinic endonuclease APE1.

PloS one 20090101

Measuring Caenorhabditis elegans life span on solid media.

Journal of visualized experiments : JoVE 20090101

Synthesis and properties of new fluorescent nucleosides and oligodeoxynucleotides derived from 5-formyl-2'-deoxyuridine.

Nucleic acids symposium series (2004) 20090101

Association of nuclear-intermediate filament lamin B1 with necrotic- and apoptotic-morphologies in cell death induced by 5-fluoro-2'-deoxyuridine.

Nucleic acids symposium series (2004) 20090101

Integrating human stem cell expansion and neuronal differentiation in bioreactors.

BMC biotechnology 20090101

Update and review of the multidisciplinary management of stage IV colorectal cancer with liver metastases.

World journal of surgical oncology 20090101

Fluorodeoxyuridine mediated cell cycle synchronization in S-phase increases the Auger radiation cell killing with 125I-iododeoxyuridine.

Nuklearmedizin. Nuclear medicine 20090101

Critical role of activating transcription factor 4 in the anabolic actions of parathyroid hormone in bone.

PloS one 20090101

Timing of locomotor activity circadian rhythms in Caenorhabditis elegans.

PloS one 20090101

Dual localized AtHscB involved in iron sulfur protein biogenesis in Arabidopsis.

PloS one 20090101

Transarterial Chemoembolization of Metastatic Colorectal Carcinoma with Drug-Eluting Beads, Irinotecan (DEBIRI): Multi-Institutional Registry.

Journal of oncology 20090101

APRIL is a novel clinical chemo-resistance biomarker in colorectal adenocarcinoma identified by gene expression profiling.

BMC cancer 20090101

RNA editing genes associated with extreme old age in humans and with lifespan in C. elegans.

PloS one 20090101

A phase II study of doxifluridine and docetaxel combination chemotherapy for advanced or recurrent gastric cancer.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20090101

Hand-foot syndrome due to capecitabine.

Indian journal of dermatology 20090101

Accumulation, activity and localization of cell cycle regulatory proteins and the chloroplast division protein FtsZ in the alga Scenedesmus quadricauda under inhibition of nuclear DNA replication.

Plant & cell physiology 20081201

[Doxifluridine, medroxyprogesterone acetate and cyclophosphamide (DMpC) combination therapy is effective against recurrent triple negative breast cancer--a case report].

Gan to kagaku ryoho. Cancer & chemotherapy 20081201

Expression and identification of folate-sensitive fragile sites in British Suffolk sheep (Ovis aries).

Journal of genetics 20081201

Simultaneous determination of doxifluridine and 5-fluorouracil in monkey serum by high performance liquid chromatography with tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115

Preferential tumor targeting and selective tumor cell cytotoxicity of 5-[131/125I]iodo-4'-thio-2'-deoxyuridine.

Clinical cancer research : an official journal of the American Association for Cancer Research 20081115

Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.

Journal of medicinal chemistry 20081113

[Establishment of a 5-DFUR-resistant human hepatocellular carcinoma cell model and preliminary study of the mechanisms of the drug resistance].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081101

Enhanced cancer cell growth inhibition by dipeptide prodrugs of floxuridine: increased transporter affinity and metabolic stability.

Molecular pharmaceutics 20081006

Efficacy of doxifluridine combined with weekly paclitaxel therapy in the treatment of advanced or recurrent breast cancer: results of the JMTO BC01 phase II trial.

Anti-cancer drugs 20081001

Polymeric nanogels containing the triphosphate form of cytotoxic nucleoside analogues show antitumor activity against breast and colorectal cancer cell lines.

Molecular cancer therapeutics 20081001

MLH1 deficiency enhances radiosensitization with 5-fluorodeoxyuridine by increasing DNA mismatches.

Molecular pharmacology 20080901

The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine.

Journal of cellular biochemistry 20080901

New insights into the pharmacology and cytotoxicity of gemcitabine and 2',2'-difluorodeoxyuridine.

Molecular cancer therapeutics 20080801

[Effect of peptide YY on subcutaneous transplantation tumor of human hepatoma in nude mice].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801

Immunochemotherapy with PSK and fluoropyrimidines improves long-term prognosis for curatively resected colorectal cancer.

Cancer biotherapy & radiopharmaceuticals 20080801

The cytostatic activity of pyrimidine nucleosides is strongly modulated by Mycoplasma hyorhinis infection: Implications for cancer therapy.

Biochemical pharmacology 20080715

Concentrations of the DNA methyltransferase inhibitor 5-fluoro-2'-deoxycytidine (FdCyd) and its cytotoxic metabolites in plasma of patients treated with FdCyd and tetrahydrouridine (THU).

Cancer chemotherapy and pharmacology 20080701

Intra and inter-molecular interactions dictate the aggregation state of irinotecan co-encapsulated with floxuridine inside liposomes.

Pharmaceutical research 20080701

Gene expression profiles of necrosis and apoptosis induced by 5-fluoro-2'-deoxyuridine.

Genomics 20080701

Intrahepatic cholangiocarcinoma: rising frequency, improved survival, and determinants of outcome after resection.

Annals of surgery 20080701

Regional chemotherapy for liver-limited metastatic colorectal cancer.

Clinical colorectal cancer 20080701

[Preparation and liver targeting of floxuridinyl dibutyrate solid lipid nanoparticles].

Yao xue xue bao = Acta pharmaceutica Sinica 20080701

Enhanced absorption and growth inhibition with amino acid monoester prodrugs of floxuridine by targeting hPEPT1 transporters.

Molecules (Basel, Switzerland) 20080628

Thymidylate synthase, thymidine phosphorylase and orotate phosphoribosyl transferase levels as predictive factors of chemotherapy in oral squamous cell carcinoma.

Acta histochemica et cytochemica 20080627

Heterogeneous ribonucleoprotein k and thymidine phosphorylase are independent prognostic and therapeutic markers for nasopharyngeal carcinoma.

Clinical cancer research : an official journal of the American Association for Cancer Research 20080615

Results of preoperative hepatic arterial infusion chemotherapy in patients undergoing liver resection for colorectal liver metastases.

Annals of surgical oncology 20080601

Assessing the optimal duration of chemotherapy in patients with colorectal liver metastases.

Journal of surgical oncology 20080601

Hepatic arterial infusion chemotherapy for metastases from colorectal cancer: is it really the end of an era?

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080601

Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase.

The FEBS journal 20080501

Association of nuclear membrane protein lamin B1 with necrosis and apoptosis in cell death induced by 5-fluoro-2'-deoxyuridine.

Nucleosides, nucleotides & nucleic acids 20080501

Novel galactosylated SLN for hepatocyte-selective targeting of floxuridinyl diacetate.

Journal of drug targeting 20080401

Chronopharmacokinetics of oral tegafur and uracil in colorectal cancer patients.

Clinical pharmacology and therapeutics 20080301

Human immunodeficiency virus 1 (HIV-1) virion infectivity factor (Vif) is part of reverse transcription complexes and acts as an accessory factor for reverse transcription.

Virology 20080301

Synthesis, cytostatic and anti-HCV activity of 6-(N-substituted aminomethyl)-, 6-(O-substituted hydroxymethyl)- and 6-(S-substituted sulfanylmethyl)purine nucleosides.

Bioorganic & medicinal chemistry 20080301

Measurement of plasma concentration of gemcitabine and its metabolite dFdU in hemodialysis patients with advanced urothelial cancer.

Japanese journal of clinical oncology 20080301

Multi-center phase II study for combination therapy with paclitaxel/doxifluridine to treat advanced/recurrent gastric cancer showing resistance to S-1 (OGSG 0302).

Japanese journal of clinical oncology 20080301

An essential role for DYF-11/MIP-T3 in assembling functional intraflagellar transport complexes.

PLoS genetics 20080301

[Current therapeutic options for liver metastasis].

Revista medica de Chile 20080301

A phase II study of irinotecan in combination with doxifluridine, an intermediate form of capecitabine, in patients with metastatic colorectal cancer.

Cancer chemotherapy and pharmacology 20080201

Simultaneous determination of gemcitabine and its main metabolite, dFdU, in plasma of patients with advanced non-small-cell lung cancer by high-performance liquid chromatography-tandem mass spectrometry.

Journal of mass spectrometry : JMS 20080201

Synthesis, cytostatic, and antiviral activity of novel 6-[2-(dialkylamino)ethyl]-, 6-(2-alkoxyethyl)-, 6-[2-(alkylsulfanyl)ethyl]-, and 6-[2-(dialkylamino)vinyl]purine nucleosides.

Bioorganic & medicinal chemistry 20080201

DNA methylation and sensitivity to antimetabolites in cancer cell lines.

Oncology reports 20080201

Folylpolyglutamate synthase and gamma-glutamyl hydrolase regulate leucovorin-enhanced 5-fluorouracil anticancer activity.

Biochemical and biophysical research communications 20080125

Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria.

The Journal of biological chemistry 20080118

Docetaxel, low-dose estramustine, and doxifluridine in hormone-refractory metastatic prostate cancer.

Cancer chemotherapy and pharmacology 20080101

Saphenous vein graft conduits for insertion of hepatic arterial infusion pumps in patients with abnormal hepatic arterial anatomy.

Journal of surgical oncology 20080101

Enhancing the activity and regioselectivity of lipases for 3'-benzoylation of floxuridine and its analogs by using ionic liquid-containing systems.

Journal of biotechnology 20080101

A phase I safety, tolerability, and pharmacokinetic study of enzastaurin combined with capecitabine in patients with advanced solid tumors.

Anti-cancer drugs 20080101

Fixed dose rate infusion of gemcitabine with oral doxifluridine and leucovorin for advanced unresectable pancreatic cancer: a phase II study.

Chemotherapy 20080101

In vivo evaluation of the uptake of [(123)I]FIAU, [(123)I]IVFRU and [(123)I]IVFAU by normal mouse brain: potential for noninvasive assessment of HSV-1 thymidine kinase gene expression in gliomas.

Nucleosides, nucleotides & nucleic acids 20080101

Systematic review of the clinical effect of glucocorticoids on nonhematologic malignancy.

BMC cancer 20080101

Transconjunctival penetration of mitomycin C.

Indian journal of ophthalmology 20080101

Age- and calorie-independent life span extension from dietary restriction by bacterial deprivation in Caenorhabditis elegans.

BMC developmental biology 20080101

HDAC inhibitors act with 5-aza-2'-deoxycytidine to inhibit cell proliferation by suppressing removal of incorporated abases in lung cancer cells.

PloS one 20080101

Antiviral activities and phosphorylation of 5-halo-2'-deoxyuridines and N-methanocarbathymidine in cells infected with vaccinia virus.

Antiviral chemistry & chemotherapy 20080101

Hemorrhage associated with hepatic artery pseudoaneurysms after regional chemotherapy with floxuridine: case report.

International seminars in surgical oncology : ISSO 20080101

Changes of gene expression of thymidine phosphorylase, thymidylate synthase, dihydropyrimidine dehydrogenase after the administration of 5'-deoxy-5-fluorouridine, paclitaxel and its combination in human gastric cancer xenografts.

Anticancer research 20080101

Disruption of neuronal autophagy by infected microglia results in neurodegeneration.

PloS one 20080101

Resistance of colorectal cancer cells to 5-FUdR and 5-FU caused by Mycoplasma infection.

Anticancer research 20080101

Development of a novel selective detection method for 5-formyl-2'-deoxyuridine by fluorescent derivatization.

Nucleic acids symposium series (2004) 20080101

Molecular mechanisms in two cell death-types, necrosis and apoptosis, induced by 5-fluoro-2'-deoxyuridine.

Nucleic acids symposium series (2004) 20080101

In vitro activity and mechanism of action of a duplex and multidrug of ethynylcytidine and 5-fluorodeoxyuridine.

Nucleic acids symposium series (2004) 20080101

Complete response of colorectal liver metastases after intra-arterial chemotherapy.

Tumori 20080101

Chronic myeloid leukemia following chemotherapy with 5'-deoxy-5-fluorouridine for gastric cancer.

Internal medicine (Tokyo, Japan) 20080101

A PP1-binding motif present in BRCA1 plays a role in its DNA repair function.

International journal of biological sciences 20080101

Potential relevance of alpha(1)-adrenergic receptor autoantibodies in refractory hypertension.

PloS one 20080101

Fluorinase-coupled base swaps: synthesis of [18F]-5'-deoxy-5'-fluorouridines.

Angewandte Chemie (International ed. in English) 20080101

Long-term actions of interleukin-1beta on delay and tonic firing neurons in rat superficial dorsal horn and their relevance to central sensitization.

Molecular pain 20080101

Thymidylate synthase, dihydropyrimidine dehydrogenase, ERCC1, and thymidine phosphorylase gene expression in primary and metastatic gastrointestinal adenocarcinoma tissue in patients treated on a phase I trial of oxaliplatin and capecitabine.

BMC cancer 20080101

Hand-foot syndrome due to capecitabine.

Indian journal of dermatology 20080101

Institutional guidelines and ongoing studies in management of liver tumours: the experience of the European Institute of Oncology.

Ecancermedicalscience 20080101

Predictors of survival after hepatic resection among patients with colorectal liver metastasis.

British journal of cancer 20071217

Meta-analysis of hepatic arterial infusion for unresectable liver metastases from colorectal cancer: the end of an era?

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071210

Hepatic arterial infusion plus systemic irinotecan in patients with unresectable hepatic metastases from colorectal cancer previously treated with systemic oxaliplatin: a retrospective analysis.

Annals of oncology : official journal of the European Society for Medical Oncology 20071201

Cytostatic evaluations of nucleoside analogs related to unnatural base pairs for a genetic expansion system.

Bioorganic & medicinal chemistry letters 20071015

In vitro and in vivo reversal of resistance to 5-fluorouracil in colorectal cancer cells with a novel stealth double-liposomal formulation.

British journal of cancer 20071008

Efficacy of the FAEV regimen in the treatment of high-risk, drug-resistant gestational trophoblastic tumor.

The Journal of reproductive medicine 20071001

Bladder tumor associated with phenacetin abuse: a case report and a review of the literature.

The Tokai journal of experimental and clinical medicine 20070920

A phase II study of irinotecan, high-dose 24-h continuous intravenous infusion of floxuridine and leucovorin (IFLUX) for advanced, previously untreated colorectal cancer.

Anti-cancer drugs 20070901

Bioavailability of the amino acid-attached prodrug as a new anti-HIV agent in rats.

Journal of veterinary science 20070901

Development and characterization of a model of liver metastasis using human colon cancer HCT-116 cells.

Biological & pharmaceutical bulletin 20070901

The histone deacetylase inhibitor sodium butyrate inhibits baculovirus-mediated transgene expression in Sf9 cells.

Journal of biotechnology 20070831

Rapid determination of gemcitabine in plasma and serum using reversed-phase HPLC.

Journal of separation science 20070801

[Efficacy of transcatheter arterial chemoembolization combined thalidomide on hepatocellular carcinoma: a controlled randomized trial].

Ai zheng = Aizheng = Chinese journal of cancer 20070801

Neoadjuvant, surgery and adjuvant chemotherapy without radiation for esophageal cancer.

Japanese journal of clinical oncology 20070801

Growth inhibition of Mycobacterium bovis, Mycobacterium tuberculosis and Mycobacterium avium in vitro: effect of 1-beta-D-2'-arabinofuranosyl and 1-(2'-deoxy-2'-fluoro-beta-D-2'-ribofuranosyl) pyrimidine nucleoside analogs.

Journal of medicinal chemistry 20070726

Combination silencer RNA (siRNA) targeting Bcl-2 antagonizes siRNA against thymidylate synthase in human tumor cell lines.

The Journal of pharmacology and experimental therapeutics 20070701

[Evaluation of combination therapy of high-dose toremifene and oral chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20070701

123I-ITdU-mediated nanoirradiation of DNA efficiently induces cell kill in HL60 leukemia cells and in doxorubicin-, beta-, or gamma-radiation-resistant cell lines.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20070601

A pitfall of propidium iodide staining in fluorescence-activated cell sorting cell cycle analysis?

Cancer research 20070601

Hand-foot syndrome with scleroderma-like change induced by the oral capecitabine: a case report.

The Korean journal of internal medicine 20070601

Pyrimidine nucleoside phosphorylase and dihydropyrimidine dihydrogenase activities as predictive factors for the efficacy of doxifluridine together with mitomycin C as adjuvant chemotherapy in primary colorectal cancer.

Hepato-gastroenterology 20070601

Dramatic age-related changes in nuclear and genome copy number in the nematode Caenorhabditis elegans.

Aging cell 20070401

Preoperative hepatic and regional arterial chemotherapy in the prevention of liver metastasis after colorectal cancer surgery.

Annals of surgery 20070401

[An inadvertent contraindicated combined use of newly prescribed TS-1 and unused doxifluridine].

Gan to kagaku ryoho. Cancer & chemotherapy 20070401

Doxifluridine combined with weekly paclitaxel for second-line treatment in patients with gastric cancer resistant to TS-1.

International journal of clinical oncology 20070401

Coencapsulation of irinotecan and floxuridine into low cholesterol-containing liposomes that coordinate drug release in vivo.

Biochimica et biophysica acta 20070301

Organotypic slice culture of the hypothalamic paraventricular nucleus of rat.

Journal of veterinary science 20070301

[Combination therapy with bi-weekly docetaxel and 5'-deoxy-5-fluorouridine for advanced gastric cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20070301

A possible role of thymidine phosphorylase expression and 5-fluorouracil increased sensitivity in oropharyngeal cancer patients.

Journal of cellular and molecular medicine 20070301

Developmental switch in the effects of TNFalpha on ventral midbrain dopaminergic neurons.

Neuroscience research 20070201

[A case of recurrent gastric cancer with peritoneal dissemination responding to doxifluridine/paclitaxel combination chemotherapy as third-line treatment].

Gan to kagaku ryoho. Cancer & chemotherapy 20070201

The Hollow Fibre Assay as a model for in vivo pharmacodynamics of fluoropyrimidines in colon cancer cells.

British journal of cancer 20070115

Rapid and simultaneous determination of capecitabine and its metabolites in mouse plasma, mouse serum, and in rabbit bile by high-performance liquid chromatography.

Journal of chromatography. A 20070105

Caspase-dependent and -independent induction of phosphatidylserine externalization during apoptosis in human renal carcinoma Cak(1)-1 and A-498 cells.

Toxicology 20070105

Tezacitabine enhances the DNA-directed effects of fluoropyrimidines in human colon cancer cells and tumor xenografts.

Biochemical pharmacology 20070101

Activity and substrate specificity of pyrimidine phosphorylases and their role in fluoropyrimidine sensitivity in colon cancer cell lines.

The international journal of biochemistry & cell biology 20070101

In vitro and in vivo antileukemic effect of novel dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine.

Neoplasma 20070101

Interventionally implanted port catheter systems for hepatic arterial infusion of chemotherapy in patients with colorectal liver metastases: a Phase II-study and historical comparison with the surgical approach.

BMC cancer 20070101

Validated assay for the simultaneous determination of the anti-cancer agent gemcitabine and its metabolite 2',2'-difluorodeoxyuridine in human plasma by high-performance liquid chromatography with tandem mass spectrometry.

Rapid communications in mass spectrometry : RCM 20070101

A clinical study of docetaxel with or without 5'DFUR as a second-line chemotherapy for advanced gastric cancer.

Medical oncology (Northwood, London, England) 20070101

Significance of thymidine phosphorylase in metronomic chemotherapy using CPT-11 and doxifluridine for advanced colorectal carcinoma.

Anticancer research 20070101

Chemosensitivity-related genes of breast cancer detected by DNA microarray.

Anticancer research 20070101

Increased preclinical efficacy of irinotecan and floxuridine coencapsulated inside liposomes is associated with tumor delivery of synergistic drug ratios.

Oncology research 20070101

Proteome and transcriptome analysis of cell death induced by 5-fluoro-2'-deoxyuridine.

Nucleic acids symposium series (2004) 20070101

Oral fluoropyrimidines may not reduce the risk of postoperative recurrence in colorectal cancer associated with mesenteric lymph node metastasis.

International surgery 20070101

A comparative study of intratumoral chemotherapy in advanced childhood common solid tumors.

Indian journal of urology : IJU : journal of the Urological Society of India 20070101

Capecitabine: an evidence-based review of its effectiveness in the treatment of carcinoma of the pancreas.

Core evidence 20070101

Human equilibrative nucleoside transporter-1 (hENT1) is required for the transcriptomic response of the nucleoside-derived drug 5'-DFUR in breast cancer MCF7 cells.

Biochemical pharmacology 20061215

Induction of thymidine phosphorylase expression by AZT contributes to enhancement of 5'-DFUR cytotoxicity.

Cancer letters 20061208

Intestinal tract injury by drugs: Importance of metabolite delivery by yellow bile road.

Pharmacology & therapeutics 20061201

Rapid microwave-assisted fluorination yielding novel 5'-deoxy-5'-fluorouridine derivatives.

Bioorganic & medicinal chemistry letters 20061201

5-FdUrd-araC heterodinucleoside re-establishes sensitivity in 5-FdUrd- and AraC-resistant MCF-7 breast cancer cells overexpressing ErbB2.

Differentiation; research in biological diversity 20061201

Unresectable gastric cancer with multiple liver metastases effectively treated with combined paclitaxel and doxifluridine chemotherapy.

International journal of clinical oncology 20061201

Is thymidylate synthase a reliable predictor for response and survival during hepatic arterial infusion for hepatic metastases from colorectal cancer?

British journal of cancer 20061106

Irinotecan cytotoxicity does not necessarily depend on the UGT1A1 polymorphism but on fluoropyrimidine: a molecular case report.

Oncology reports 20061101

p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans.

PLoS genetics 20061101

[A treatment for pulmonary metastases from colorectal cancer by pre-operative CPT-11/5'-DFUR combination therapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20061101

[A case of colon cancer liver metastases treated by combined therapies].

Gan to kagaku ryoho. Cancer & chemotherapy 20061101

Genomic copy number changes affecting the thymidylate synthase (TYMS) gene in cancer: a model for patient classification to aid fluoropyrimidine therapy.

Cancer research 20061001

Nonsurgical approaches to colorectal cancer.

The oncologist 20061001

[Effectiveness of preoperative chemoradiotherapy for advanced rectal cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20061001

[A case of advanced gastric cancer--efficacy of combination therapy of doxifluridine and weekly paclitaxel].

Gan to kagaku ryoho. Cancer & chemotherapy 20061001

[A case of stage IVA intrahepatic biliary tract cancer successfully treated with gemcitabine].

Gan to kagaku ryoho. Cancer & chemotherapy 20061001

Pump removal in infected patients with hepatic chemotherapy pumps: when is it necessary?

The American surgeon 20061001

Uridine phosphorylase in breast cancer: a new prognostic factor?

Frontiers in bioscience : a journal and virtual library 20060901

A phase II trial of neoadjuvant cisplatin-fluorouracil followed by postoperative intraperitoneal floxuridine-leucovorin in patients with locally advanced gastric cancer.

Annals of oncology : official journal of the European Society for Medical Oncology 20060901

The relationship of premature mitosis to cytotoxicity in response to checkpoint abrogation and antimetabolite treatment.

Cell cycle (Georgetown, Tex.) 20060901

Fluorodeoxyuridine modulates cellular expression of the DNA base excision repair enzyme uracil-DNA glycosylase.

Cancer research 20060901

[A case of local recurrence of rectal cancer in long-term responding to combined therapy of low-dose CPT-11 and 5'-DFUR].

Gan to kagaku ryoho. Cancer & chemotherapy 20060901

Thymidylate synthase as a chemotherapeutic drug target: where are we after fifty years?

Cancer biology & therapy 20060901

The radiosensitising effect of difluorodeoxyuridine, a metabolite of gemcitabine, in vitro.

Cancer chemotherapy and pharmacology 20060801

A proposed clinical test for monitoring fluoropyrimidine therapy: detection and stability of thymidylate synthase ternary complexes.

Cancer biology & therapy 20060801

Synergistic cytotoxic interaction in hormone-refractory prostate cancer with the triple combination docetaxel-erlotinib and 5-fluoro-5'-deoxyuridine.

Anti-cancer drugs 20060801

Relationship between AUC of 5'-DFUR and toxicity of capecitabine, fluoropyrimidine carbamate analogs, and 5'-DFUR in monkeys, mice, and rats.

The Journal of toxicological sciences 20060801

The role of haemoglobin level in predicting the response to first-line chemotherapy in advanced colorectal cancer patients.

British journal of cancer 20060703

Molecular imaging with 123I-FIAU, 18F-FUdR, 18F-FET, and 18F-FDG for monitoring herpes simplex virus type 1 thymidine kinase and ganciclovir prodrug activation gene therapy of cancer.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20060701

Two membrane-associated tyrosine phosphatase homologs potentiate C. elegans AKT-1/PKB signaling.

PLoS genetics 20060701

Ratiometric dosing of anticancer drug combinations: controlling drug ratios after systemic administration regulates therapeutic activity in tumor-bearing mice.

Molecular cancer therapeutics 20060701

Concurrent chemoradiotherapy with doxifluridine and paclitaxel for extrahepatic bile duct cancer.

American journal of clinical oncology 20060601

[Evaluation of safety and efficacy for bi-weekly Docetaxel and 5'-DFUR combination therapy in patients with advanced or recurrent breast cancer--Phase I study].

Gan to kagaku ryoho. Cancer & chemotherapy 20060601

Endoscopic ultrasound restaging after neoadjuvant chemotherapy in esophageal cancer.

The American journal of gastroenterology 20060601

The MMP-9 expression determined the efficacy of postoperative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.

Cancer chemotherapy and pharmacology 20060501

Short fluorodeoxyuridine exposure of different human glioblastoma lines induces high-level accumulation of S-phase cells that avidly incorporate 125I-iododeoxyuridine.

European journal of nuclear medicine and molecular imaging 20060501

Downstaging colorectal liver metastases by concomitant unilateral portal vein ligation and selective intra-arterial chemotherapy.

The British journal of surgery 20060501

High-performance liquid chromatographic method for the determination of gemcitabine and 2',2'-difluorodeoxyuridine in plasma and tissue culture media.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060501

The expression of vascular endothelial growth factor determines the efficacy of post-operative adjuvant chemotherapy using oral fluoropyrimidines in stage II or III colorectal cancer.

Oncology reports 20060501

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Improved survival and response to hepatic infusion.

The Lancet. Oncology 20060501

Adjuvant hepatic chemotherapy after resection of solitary hepatocellular carcinoma associated with hepatitis B virus cirrhosis.

Hepatobiliary & pancreatic diseases international : HBPD INT 20060501

Emerging efficacy endpoints for targeted therapies in advanced renal cell carcinoma.

Oncology (Williston Park, N.Y.) 20060501

Modulation of uridine phosphorylase gene expression by tumor necrosis factor-alpha enhances the antiproliferative activity of the capecitabine intermediate 5'-deoxy-5-fluorouridine in breast cancer cells.

Molecular pharmacology 20060401

Pharmacokinetics of gemcitabine and its primary metabolite in dogs after intravenous bolus dosing and its in vitro pharmacodynamics.

Journal of veterinary pharmacology and therapeutics 20060401

Pharmacokinetics of gemcitabine and its primary metabolite in dogs after intravenous infusion.

Journal of veterinary pharmacology and therapeutics 20060401

[A case of gastric cancer with multiple liver metastases resistant to TS-1 responding to chemotherapy with paclitaxel plus doxifluridine].

Gan to kagaku ryoho. Cancer & chemotherapy 20060401

Chemotherapy-induced sclerosing cholangitis: long-term response to endoscopic therapy.

Journal of clinical gastroenterology 20060401

Supportive care in the management of colon cancer.

Supportive cancer therapy 20060401

Apoptosis induced by preoperative oral 5'-DFUR administration in gastric adenocarcinoma and its mechanism of action.

World journal of gastroenterology 20060307

[Combined chemotherapy with weekly Paclitaxel and doxifluridine for advanced and recurrent gastric cancers].

Gan to kagaku ryoho. Cancer & chemotherapy 20060301

[A case of recurrent gastric cancer effectively treated by combination chemotherapy of weekly paclitaxel and 5'- DFUR after showing resistance to weekly paclitaxel].

Gan to kagaku ryoho. Cancer & chemotherapy 20060301

Analysis of mechanisms contributing to AraC-mediated chemoresistance and re-establishment of drug sensitivity by the novel heterodinucleoside phosphate 5-FdUrd-araC.

Apoptosis : an international journal on programmed cell death 20060301

3D-QSAR studies on antitubercular thymidine monophosphate kinase inhibitors based on different alignment methods.

Bioorganic & medicinal chemistry letters 20060215

Nucleoside ester prodrug substrate specificity of liver carboxylesterase.

The Journal of pharmacology and experimental therapeutics 20060201

Interaction of intestinal nucleoside transporter hCNT2 with amino acid ester prodrugs of floxuridine and 2-bromo-5,6-dichloro-1-beta-D-ribofuranosylbenzimidazole.

Biological & pharmaceutical bulletin 20060201

[A long-term survivor with stage IV gastric cancer due to postoperative weekly paclitaxel and 5'-DFUR combination therapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20060201

[Efficacy of FAEV regimen in treatment of high-risk drug-resistant gestational trophoblastic tumor].

Zhonghua fu chan ke za zhi 20060201

Nuclear expression of thymidylate synthase in colorectal cancer cell lines and clinical samples.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20060101

Upregulation of thymidine phosphorylase in rectal cancer tissues by mitomycin C.

Journal of surgical oncology 20060101

Radiation sensitiser effective against liver disease.

The Lancet. Oncology 20060101

Altered mouse leukemia L1210 thymidylate synthase, associated with cell resistance to 5-fluoro-dUrd, is not mutated but rather reflects posttranslational modification.

Acta biochimica Polonica 20060101

Hepatic arterial infusion of chemotherapy for hepatic metastases from colorectal cancer.

Cancer control : journal of the Moffitt Cancer Center 20060101

Comparative effects of the administration period of adjuvant chemotherapy using doxifluridine (5'-DFUR) for 1 year versus 3 years after breast cancer surgery by the Shimane Breast Cancer Study Group.

Anticancer research 20060101

The role of thymidine phosphorylase and uridine phosphorylase in (fluoro)pyrimidine metabolism in peripheral blood mononuclear cells.

The international journal of biochemistry & cell biology 20060101

Dopamine presynaptically and heterogeneously modulates nucleus accumbens medium-spiny neuron GABA synapses in vitro.

BMC neuroscience 20060101

Transient expression of Drosophila melanogaster deoxynucleoside kinase gene enhances cytotoxicity of nucleoside analogs.

Nucleosides, nucleotides & nucleic acids 20060101

Synthesis and biological activity of N-2,3-dihydroxypropyl-N-4-chlorobutyl nucleoside phosphoramidate prodrugs.

Molecular pharmaceutics 20060101

Clinical usefulness of oral combination chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR) and cyclophosphamide for metastatic breast cancer.

Breast cancer (Tokyo, Japan) 20060101

Proteome and transcriptome analysis of 5-fluoro-2'-deoxyuridine-induced cell death mechanisms.

Nucleic acids symposium series (2004) 20060101

Morphine stimulates CCL2 production by human neurons.

Journal of neuroinflammation 20060101

Hepatic arterial chemotherapy in combination with systemic chemotherapy compared with hepatic arterial chemotherapy alone for liver metastases from colorectal cancer: results of a multi-centric randomized study.

In vivo (Athens, Greece) 20060101

Hepatic metastases of colorectal cancer: locoregional intra-arterial treatment.

Anticancer research 20060101

Trans-arterial hepatic radioembolisation of yttrium-90 microspheres.

Biomedical imaging and intervention journal 20060101

Synthesis and in vitro anti-mycobacterial activity of 5-substituted pyrimidine nucleosides.

Bioorganic & medicinal chemistry 20051215

Effects on DNA and RNA after the administration of two different schedules of 5-fluorouracil in colorectal cancer patients.

Cancer chemotherapy and pharmacology 20051201

Pharmacokinetic modelling of 5-FU production from capecitabine--a population study in 40 adult patients with metastatic cancer.

Journal of pharmacokinetics and pharmacodynamics 20051201

Phase II trial of high-dose conformal radiation therapy with concurrent hepatic artery floxuridine for unresectable intrahepatic malignancies.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051201

[Pharmacokinetic comparison of capecitabine and 5'-deoxy-5-fluorouridine (doxifluridine; 5'-DFUR)].

Gan to kagaku ryoho. Cancer & chemotherapy 20051201

Lifespan extending activity of substances secreted by the nematode Caenorhabditis elegans that include the dauer-inducing pheromone.

Bioscience, biotechnology, and biochemistry 20051201

Neoadjuvant chemotherapy, surgery, and adjuvant intraperitoneal chemotherapy in patients with locally advanced gastric or gastroesophageal junction carcinoma: a phase II study.

Seminars in oncology 20051201

Simultaneous determination of capecitabine and its metabolites by HPLC and mass spectrometry for preclinical and clinical studies.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051105

Polymorphic tandem repeat sequences of the thymidylate synthase gene correlates with cellular-based sensitivity to fluoropyrimidine antitumor agents.

Cancer chemotherapy and pharmacology 20051101

[A case of advanced gastric cancer with direct invasion of the transverse colon responding to paclitaxel/5'-DFUR combined therapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20051101

Phase I clinical and pharmacologic study of a 2-weekly administration of cisplatin and gemcitabine in patients with advanced non-small cell lung cancer.

Anti-cancer drugs 20051001

[Prediction and treatment of peritoneal dissemination in gastric cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20051001

[Case report--postoperative continuous intraarterial infusion of small doses of 5-FU successfully controlled residual tumor and liver metastasis of stage IV gastric cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20051001

[A case of metastatic colon cancer treated with oxaliplatin combination chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20051001

[A case of chemoradiation with tissue expander for local reccurence of rectal cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20051001

Preferential inhibition of bone metastases by 5'-deoxy-5-fluorouridine and capecitabine in the 4T1/luc mouse breast cancer model.

Oncology reports 20050901

Floxuridine amino acid ester prodrugs: enhancing Caco-2 permeability and resistance to glycosidic bond metabolism.

Pharmaceutical research 20050901

[Experience of weekly paclitaxel combined with orally administered doxifluridine therapy for advanced and recurrent gastric cancer-preliminary study].

Gan to kagaku ryoho. Cancer & chemotherapy 20050901

Level of 5-fluorodeoxyuridine 5'-monophosphate in cancerous tissue in patients with gastric cancer under preoperative administration of TS-1. A preliminary study.

Journal of experimental & clinical cancer research : CR 20050901

A phase I study of doxifluridine combined with weekly paclitaxel for metastatic gastric cancer.

Cancer chemotherapy and pharmacology 20050801

Pharmacokinetic and pharmacodynamic comparison of fluoropyrimidine derivatives, capecitabine and 5'-deoxy-5-fluorouridine (5'-DFUR).

Cancer chemotherapy and pharmacology 20050801

Transfection of thymidine phosphorylase cDNA to human hepatocellular carcinoma cells enhances sensitivity to fluoropyrimidine but augments endothelial cell migration.

Journal of cancer research and clinical oncology 20050801

Phase I trial of systemic oxaliplatin combination chemotherapy with hepatic arterial infusion in patients with unresectable liver metastases from colorectal cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801

A role for hepatic-directed chemotherapy in colorectal liver metastases.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801

Improved hepatic toxicity profile of portal vein adjuvant hepatic infusional chemotherapy.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050801

Hepatic arterial infusion of floxuridine and dexamethasone plus high-dose Mitomycin C for patients with unresectable hepatic metastases from colorectal carcinoma.

Journal of surgical oncology 20050801

Continuous intrathecal administration of 5-fluoro-2'-deoxyuridine for the treatment of neoplastic meningitis.

Neurosurgery 20050801

[Experience with capecitabine in patients with anthracycline and/or taxane-resistant recurrent breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20050801

Intrathecal administration of Y-27632, a specific rho-associated kinase inhibitor, for rat neoplastic meningitis.

Molecular cancer research : MCR 20050801

Improvement in 5-fluorouracil (5-FU) and 5-fluoro-2'-deoxyuridine (FdUrd) concentration by 5-fluorouracil-polyethylene-glycol-liposomes in abdominal stop-flow: treatment of VX2 liver-tumor-bearing rabbits.

Journal of chemotherapy (Florence, Italy) 20050801

5-Fluorouracil concentration in blood, liver and tumor tissues and apoptosis of tumor cells after preoperative oral 5'-deoxy-5-fluorouridine in patients with hepatocellular carcinoma.

World journal of gastroenterology 20050707

Cytotoxic effects of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine in cross-resistant H9 human lymphoma cells.

Leukemia research 20050701

Correlations between antitumor activities of fluoropyrimidines and DPD activity in lung tumor xenografts.

Oncology reports 20050701

Enhancement of antitumor activity of 5'-deoxy-5-fluorouridine (Furtulon) by taxane in human gastric cancer xenografts.

Oncology reports 20050701

Combination of 5-deoxy-5-fluorouridine and tamoxifen show cell-type specific antagonistic and cooperative effects on cytotoxicity in human mammary carcinoma cells.

Oncology reports 20050701

A human osteosarcoma cell line expressing herpes simplex type-1 thymidine kinase: studies with radiolabeled (E)-5-(2-iodovinyl)-2'-fluoro-2'-deoxyuridine.

Nuclear medicine and biology 20050701

Enhancement of 5-fluorouracil sensitivity by an rTS signaling mimic in H630 colon cancer cells.

Cancer research 20050701

[Long-term survival in a case of large bowel cancer--efficacy of CPT-11-based chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20050701

Charge transfer excited-state dynamics in DNA duplexes substituted with an ethynylpyrenyldeoxyuridine electron source and a fluorodeoxyuridine electron trap.

The journal of physical chemistry. B 20050623

Effects of oral 5-fluorouracil drugs on hepatic fat content in patients with colon cancer.

Academic radiology 20050601

Bile duct complications of hepatic arterial infusion chemotherapy evaluated by helical CT.

Clinical radiology 20050601

Hypoxia-selective activation of 5-fluorodeoxyuridine prodrug possessing indolequinone structure: radiolytic reduction and cytotoxicity characteristics.

Bioorganic & medicinal chemistry letters 20050502

Doxycycline may reduce the incidence of aneurysms in haemodialysis vascular accesses.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050501

The multidrug resistance protein 5 (ABCC5) confers resistance to 5-fluorouracil and transports its monophosphorylated metabolites.

Molecular cancer therapeutics 20050501

[Bi-weekly chemotherapy with medium-dose docetaxel for advanced and recurrent breast cancers (The 15th study of Keiji Breast Cancer Study Group)].

Gan to kagaku ryoho. Cancer & chemotherapy 20050501

[Two cases of advanced breast cancer responding to oral chemoendocrine therapy with 5'-deoxy-5-fluorouridine, medroxyprogesterone acetate and cyclophosphamide (DMpC)].

Gan to kagaku ryoho. Cancer & chemotherapy 20050501

Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes.

The Journal of biological chemistry 20050422

Yeast DEL assay detects clastogens.

Mutation research 20050404

Development of a stereological method to measure levels of fluoropyrimidine metabolizing enzymes in tumor sections using laser scanning cytometry.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20050401

Thymidine phosphorylase expression and efficacy of adjuvant doxifluridine in advanced colorectal cancer patients.

Oncology reports 20050401

Severe drug toxicity associated with a single-nucleotide polymorphism of the cytidine deaminase gene in a Japanese cancer patient treated with gemcitabine plus cisplatin.

Clinical cancer research : an official journal of the American Association for Cancer Research 20050401

Targeted delivery to PEPT1-overexpressing cells: acidic, basic, and secondary floxuridine amino acid ester prodrugs.

Molecular cancer therapeutics 20050401

[A case of recurrent breast cancer with multiple lung, adrenal, inferior vena cava tumor thrombus and bone metastases successfully treated with 5'-DFUR and hormonal therapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20050401

Is there a new drug beyond floxuridine for intra-arterial hepatic chemotherapy in liver metastases from colorectal cancer?

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050320

Tumor necrosis factor alpha-dependent drug resistance to purine and pyrimidine analogues in human colon tumor cells mediated through IKK.

The Journal of biological chemistry 20050304

Taxotere-5'-deoxy-5-fluorouridine combination on hormone-refractory human prostate cancer cells.

Anti-cancer drugs 20050301

Sequential treatment with irinotecan and doxifluridine: optimal dosing schedule in murine models and in a phase I study for metastatic colorectal cancer.

Chemotherapy 20050301

[Weekly paclitaxel administration and intraabdominal CBDCA injection possibly beneficial treatment for recurrent breast cancer associated with metastatic ovarian cancer and peritoneal dissemination after operation--a case report].

Gan to kagaku ryoho. Cancer & chemotherapy 20050301

[Effective reduction of elevated tumor markers by exemestane--a 12-year follow-up of a case of bone metastatic breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20050301

A new class of 5-fluoro-2'-deoxyuridine prodrugs conjugated with a tumor-homing cyclic peptide CNGRC by ester linkers: synthesis, reactivity, and tumor-cell-selective cytotoxicity.

Pharmaceutical research 20050301

DNA mismatch repair-dependent response to fluoropyrimidine-generated damage.

The Journal of biological chemistry 20050218

Global expression changes resulting from loss of telomeric DNA in fission yeast.

Genome biology 20050101

Gene expression profiling revealed novel mechanism of action of Taxotere and Furtulon in prostate cancer cells.

BMC cancer 20050101

Advanced gastric cancer with peritoneal dissemination successfully treated with paclitaxel and doxifluridine: a case report.

Hepato-gastroenterology 20050101

Heterodinucleoside phosphates of 5-fluorodeoxyuridine and arabinofuranosylcytosine--new drugs in cancer chemotherapy?

In vivo (Athens, Greece) 20050101

A combination phase I study of weekly paclitaxel and doxifluridine in advanced gastric cancer patients.

Anticancer research 20050101

CD134 as target for specific drug delivery to auto-aggressive CD4+ T cells in adjuvant arthritis.

Arthritis research & therapy 20050101

Localized hand-foot syndrome after intra-arterial hepatic chemotherapy with floxuridine: a clinical case.

Tumori 20050101

Cancer cell adaptation to chemotherapy.

BMC cancer 20050101

An encoded N-terminal extension results in low levels of heterologous protein production in Escherichia coli.

Microbial cell factories 20050101

Intravesical gemcitabine in superficial bladder cancer: a phase II safety, efficacy and pharmacokinetic study.

Anticancer research 20050101

The benefit of post-operative adjuvant chemotherapy using oral fluoropyrimidines in rectal cancer.

The Kurume medical journal 20050101

Recognition of an unnatural difluorophenyl nucleotide by uracil DNA glycosylase.

Biochemistry 20041214

Gene expression profiles of colorectal carcinoma in response to neo-adjuvant chemotherapy.

International journal of oncology 20041201

Determination of gemcitabine and its metabolite in human plasma using high-pressure liquid chromatography coupled with a diode array detector.

Acta pharmacologica Sinica 20041201

A prospective randomized study of gemcitabine with doxifluridine versus paclitaxel with doxifluridine in concurrent chemoradiotherapy for locally advanced pancreatic cancer.

International journal of radiation oncology, biology, physics 20041201

Morbidity of adjuvant hepatic arterial infusion pump chemotherapy in the management of colorectal cancer metastatic to the liver.

American journal of surgery 20041201

[Successful combination therapy with 5'-DFUR and MPA for breast cancer with spinal and vertebral metastases].

Gan to kagaku ryoho. Cancer & chemotherapy 20041201

[Docetaxel (TXT), epirubicin (EPI) and doxifluridine (5'-DFUR) combination neoadjuvant chemotherapy for outpatients with locally advanced breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20041201

[Significance of tissue thymidine phosphorylase and dihydropyrimidine dehydrogenase activities in ovarian cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20041201

Phase I clinical trial of fixed-dose rate infusional gemcitabine and dacarbazine in the treatment of advanced soft tissue sarcoma, with assessment of gemcitabine triphosphate accumulation.

Cancer 20041115

Important role of the dihydrouracil/uracil ratio in marked interpatient variations of fluoropyrimidine pharmacokinetics and pharmacodynamics.

Journal of clinical pharmacology 20041101

Lack of contribution of dihydrofluorouracil and alpha-fluoro-beta-alanine to the cytotoxicity of 5'-deoxy-5-fluorouridine on human keratinocytes.

Anti-cancer drugs 20041101

Integrated FDG PET/CT in patients with persistent ovarian cancer: correlation with histologic findings.

Radiology 20041101

[Current combination chemotherapy containing paclitaxel for advanced, recurrent gastric cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20041101

A phase II trial of FUdR in patients with advanced pancreatic cancer.

Journal of cancer research and clinical oncology 20041001

Distribution of 1-(2-deoxy-2-fluoro-beta-D-arabinofuranosyl) uracil in mice bearing colorectal cancer xenografts: rationale for therapeutic use and as a positron emission tomography probe for thymidylate synthase.

Clinical cancer research : an official journal of the American Association for Cancer Research 20041001

[Combination therapy with Anastrozole and 5'-DFUR as a treatment for metastatic breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20041001

The efficacy of long-term oral chemotherapy with 5'-deoxy-5-fluorouridine and cyclophosphamide for recurrent breast cancer.

International journal of clinical oncology 20041001

[A case of disseminated tumor from cecal cancer with survival for over 5 years after twice surgical resection and systemic chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20041001

[A case of long-term survival after chemo-radiation for postoperative local recurrence of rectal cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20041001

[Effectiveness of chemoradiotherapy for three cases of squamous cell anal carcinoma].

Gan to kagaku ryoho. Cancer & chemotherapy 20041001

A non-radioactive sensitive assay to measure 5-fluorouracil incorporation into DNA of solid tumors.

Nucleosides, nucleotides & nucleic acids 20041001

5-Fluoro-2'-deoxyuridine has effects on mitochondria in CEM T-lymphoblast cells.

Nucleosides, nucleotides & nucleic acids 20041001

Effect of fluoropyrimidines on the growth of Ureaplasma urealyticum.

Nucleosides, nucleotides & nucleic acids 20041001

Cytotoxic and apoptotic effects of novel heterodinucleoside phosphates consisting of 5-fluorodeoxyuridine and Ara-C in human cancer cell lines.

Nucleosides, nucleotides & nucleic acids 20041001

Investigation of the pharmacokinetics of gemcitabine and 2',2'-difluorodeoxyuridine in human plasma by liquid chromatography.

Analytical biochemistry 20040915

5-fluoro-2'-deoxyuridine-induced cdc25A accumulation correlates with premature mitotic entry and clonogenic death in human colon cancer cells.

Cancer research 20040915

Cytotoxic chemotherapy for metastatic renal cell carcinoma.

Der Urologe. Ausg. A 20040901

A novel combination antimetabolite, TAS-102, exhibits antitumor activity in FU-resistant human cancer cells through a mechanism involving FTD incorporation in DNA.

International journal of oncology 20040901

Small interfering RNA-mediated suppression of dUTPase sensitizes cancer cell lines to thymidylate synthase inhibition.

Molecular pharmacology 20040901

[The association of expression and gene polymorphism of the thymidylate synthase gene with 5-fluoro-5'-deoxyuridine sensitivity in gastric cancer cell lines].

Gan to kagaku ryoho. Cancer & chemotherapy 20040901

[A long-surviving patient with Stage IV breast cancer with no recurrence after combined therapy of medroxy progesterone acetate (MPA) and intra-arterial infusion chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20040901

[The effect of pre-operative chemotherapy on calpain in cells of gastrointestinal malignant tumors].

Zhonghua wai ke za zhi [Chinese journal of surgery] 20040807

Plasma concentrations of 5-fluorouracil and its metabolites in colon cancer patients.

Pharmacological research 20040801

Effects of oxaliplatin and CPT-11 on cytotoxicity and nucleic acid incorporation of the fluoropyrimidines.

Journal of cancer research and clinical oncology 20040801

Hepatic arterial infusion chemotherapy for metastatic colorectal cancer: a concise overview.

Cancer treatment reviews 20040801

In vitro and in vivo antitumor activity of novel amphiphilic dimers consisting of 5-fluorodeoxyuridine and arabinofuranosylcytosine.

International journal of oncology 20040801

Hepatic artery infusion chemotherapy for metastatic colorectal cancer to the liver at the lahey clinic: comparison between two methods of treatment, surgical versus percutaneous catheter placement.

American journal of clinical oncology 20040801

[Enhancement effect of interferon gamma on the sensitivity of RT4 bladder cancer cells to 5'-deoxy-5-fluorouridine,and 5-fluorouracil through up-regulation of PD-ECGF/TP].

Ai zheng = Aizheng = Chinese journal of cancer 20040801

[A case of liver metastasis of colon cancer responding remarkably to 5'-DFUR].

Gan to kagaku ryoho. Cancer & chemotherapy 20040801

Dihydropyrimidine dehydrogenase deficiency: impact of pharmacogenetics on 5-fluorouracil therapy.

Clinical advances in hematology & oncology : H&O 20040801

The HPV16 E6/E7 oncogene sensitizes human ovarian surface epithelial cells to low-dose but not high-dose 5-FU and 5-FUdR.

Biochemical and biophysical research communications 20040716

Thymidylate synthase inhibition triggers glucose-dependent apoptosis in p53-negative leukemic cells.

FEBS letters 20040716

The ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase in tumour tissues of patients with metastatic gastric cancer is predictive of the clinical response to 5'-deoxy-5-fluorouridine.

European journal of cancer (Oxford, England : 1990) 20040701

Prediction of 5'-deoxy-5-fluorouridine sensitivity in colorectal cancer cases by thymidine phosphorylase activity and preliminary identification of susceptibility related genes.

Oncology reports 20040701

Bioactivation of capecitabine in human liver: involvement of the cytosolic enzyme on 5'-deoxy-5-fluorocytidine formation.

Drug metabolism and disposition: the biological fate of chemicals 20040701

Doxifluridine-induced neurotoxicity with normal dihydropyrimidine dehydrogenase activity.

Neurology 20040608

Therapeutic effects of novel anti-tumor reagent, apoptosis inducing nucleosides from CD57+HLA-DRbright natural suppressor cell line on human gastric carcinoma-bearing SCID mice.

International journal of oncology 20040601

Complications after percutaneous transaxillary implantation of a catheter for intraarterial chemotherapy of liver tumors: clinical relevance and management in 204 patients.

AJR. American journal of roentgenology 20040601

Gemcitabine in patients with solid tumors and renal impairment: a pharmacokinetic phase I study.

American journal of clinical oncology 20040601

Intra-aortal therapy with 5-fluorouracil- polyethylene glycol stealth liposomes: does the metabolism of 5-fluorouracil into 5-fluoro-2'-deoxyuridine depend on ph value?. An animal study in VX-2 liver tumor-bearing rabbits.

Chemotherapy 20040601

Floxuridine-containing regimens in the treatment of gestational trophoblastic tumor.

The Journal of reproductive medicine 20040601

Highly efficient DNA incorporation of intratumourally injected [125I]iododeoxyuridine under thymidine synthesis blocking in human glioblastoma xenografts.

International journal of cancer 20040520

Rational combinations of trastuzumab with chemotherapeutic drugs used in the treatment of breast cancer.

Journal of the National Cancer Institute 20040519

[Thymidine phosphorylase expressed in monocyte-macrophages enhanced anticancer effect of 5'-deoxy-5-fluorouridine on colorectal carcinoma cells].

Zhonghua yi xue za zhi 20040502

Comparison of intraperitoneal continuous infusion of floxuridine and bolus administration in a peritoneal gastric cancer xenograft model.

Cancer chemotherapy and pharmacology 20040501

Defining the role of hepatic arterial infusion chemotherapy in metastatic colorectal cancer.

Oncology (Williston Park, N.Y.) 20040501

S-1-induced, prolonged complete regression of lung metastasis from gastric cancer refractory to 5'-DFUR: a case report with pharmacokinetic study.

Japanese journal of clinical oncology 20040501

Uridine phosophorylase: an important enzyme in pyrimidine metabolism and fluoropyrimidine activation.

Drugs of today (Barcelona, Spain : 1998) 20040501

Translocation (11;13)(q23;q14) as the sole abnormality in a childhood de novo acute myelocytic leukemia.

Cancer genetics and cytogenetics 20040401

Interactions of nucleoside analogs, caffeine, and nicotine with human concentrative nucleoside transporters 1 and 2 stably produced in a transport-defective human cell line.

Molecular pharmacology 20040401

Regional chemotherapeutic techniques for liver tumors: current knowledge and future directions.

The Surgical clinics of North America 20040401

[A case of advanced gastric cancer successfully treated with neoadjuvant chemotherapy of combined weekly paclitaxel and doxifluridine (5'-DFUR)].

Gan to kagaku ryoho. Cancer & chemotherapy 20040401

Design and synthesis of 3'- and 5'-O-(3-benzenesulfonylfuroxan-4-yl)-2'-deoxyuridines: biological evaluation as hybrid nitric oxide donor-nucleoside anticancer agents.

Journal of medicinal chemistry 20040325

[Two cases of metastatic or recurrent rectal cancer responding to combined chemotherapy of low-dose CPT-11 and 5'-DFUR as second-line chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20040301

[Immunotherapy of metastatic renal cell carcinoma: report of 28 cases].

Zhonghua wai ke za zhi [Chinese journal of surgery] 20040222

In vitro and in vivo evaluation of novel antitumor prodrugs of 5-fluoro-2'-deoxyuridine activated by hypoxic irradiation.

International journal of radiation oncology, biology, physics 20040201

[A case of 10-year survival after combination chemotherapy of 5'-deoxy-5-fluorouridine and cisplatin and adjuvant surgery for gastric cancer with liver metastasis].

Gan to kagaku ryoho. Cancer & chemotherapy 20040201

Correlation of thymidylate synthase, thymidine phosphorylase and dihydropyrimidine dehydrogenase with sensitivity of gastrointestinal cancer cells to 5-fluorouracil and 5-fluoro-2'-deoxyuridine.

World journal of gastroenterology 20040115

Enzyme-prodrug systems: thymidine phosphorylase/5'-deoxy-5-fluorouridine.

Methods in molecular medicine 20040101

In vivo comparison of IVDU and IVFRU in HSV1-TK gene expressing tumor bearing rats.

Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20040101

Effects of dexamethasone or celecoxib on biliary toxicity after hepatic arterial infusion of 5-fluorodeoxyuridine in a canine model.

Cancer research 20040101

Thymidylate synthetase mRNA levels are increased in liver metastases of colorectal cancer patients resistant to fluoropyrimidine-based chemotherapy.

BMC cancer 20040101

The role of radiotherapy in the treatment of liver metastases.

Cancer journal (Sudbury, Mass.) 20040101

Validated procedure for simultaneous trace level determination of the anti-cancer agent gemcitabine and its metabolite in human urine by high-performance liquid chromatography with tandem mass spectrometry.

Rapid communications in mass spectrometry : RCM 20040101

The comet assay differentiates efficiently and rapidly between genotoxins and cytotoxins in quiescent cells.

Cell biology international 20040101

Oral 5-FU is a more effective antimetastatic agent than UFT.

Anticancer research 20040101

Combination chemotherapy with docetaxel and doxifluridine showed a beneficial outcome in advanced or recurrent breast cancer patients with longer disease-free interval.

Anticancer research 20040101

A randomized controlled study of immunochemotherapy with OK-432 after curative surgery for gastric cancer.

Journal of immunotherapy (Hagerstown, Md. : 1997) 20040101

Randomized phase II study comparing mitomycin, cisplatin plus doxifluridine with cisplatin plus doxifluridine in advanced unresectable gastric cancer.

Anticancer research 20040101

Role of DNA mismatch repair in apoptotic responses to therapeutic agents.

Environmental and molecular mutagenesis 20040101

[Antisense oligonucleotides with antitumor activity].

Magyar onkologia 20040101

Comparative antitumor activity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in combination with interferon-alpha in renal cell carcinoma cell lines.

Urologia internationalis 20040101

Fixation methods for implantable port chamber: comparative study using glue, self-stabilizing leg and suture fixations in rabbits.

Korean journal of radiology 20040101

Novel prophylactic effect of doxifluridine in superficial bladder cancer.

Scandinavian journal of urology and nephrology 20040101

A phase I and pharmacologic study of weekly gemcitabine in combination with infusional 5-fluorodeoxyuridine and oral calcium leucovorin.

Cancer chemotherapy and pharmacology 20031201

[A case of breast cancer with lung and bone metastasis treated successfully by oral combination chemotherapy of 5'-deoxy-5-fluorouridine and cyclophosphamide].

Gan to kagaku ryoho. Cancer & chemotherapy 20031201

In vivo monitoring of capecitabine metabolism in human liver by 19fluorine magnetic resonance spectroscopy at 1.5 and 3 Tesla field strength.

Cancer research 20031115

The potential for oral combination chemotherapy of 5'-deoxy-5-fluorouridine, a 5-FU prodrug, and cyclophosphamide for metastatic breast cancer.

British journal of cancer 20031103

Comparative study of three methods for non-radioactive in vivo DNA labeling in Escherichia coli using nucleoside analogs.

Preparative biochemistry & biotechnology 20031101

[A case of advanced breast cancer with multiple lung, bone and lymph node metastases successfully treated with 5'-DFUR alone].

Gan to kagaku ryoho. Cancer & chemotherapy 20031101

[Concomitant whole brain radiotherapy and FUDR+VM-26+DDP chemotherapy in brain metastasis of non-small cell lung cancer: a report of short term efficacy].

Zhongguo fei ai za zhi = Chinese journal of lung cancer 20031020

One-electron reduction characteristics of N(3)-substituted 5-fluorodeoxyuridines synthesized as radiation-activated prodrugs.

Bioorganic & medicinal chemistry 20031015

ZD1839 (Iressa) modifies the activity of key enzymes linked to fluoropyrimidine activity: rational basis for a new combination therapy with capecitabine.

Clinical cancer research : an official journal of the American Association for Cancer Research 20031015

An expedient assay for determination of gemcitabine and its metabolite in human plasma using isocratic ion-pair reversed-phase high-performance liquid chromatography.

Therapeutic drug monitoring 20031001

Review article: colorectal cancer chemotherapy.

Alimentary pharmacology & therapeutics 20031001

[A case of multiple liver metastases of colon cancer with PyNPase-positive successfully treated with 5'-DFUR].

Gan to kagaku ryoho. Cancer & chemotherapy 20031001

[A case of hepatic metastasis and local recurrence from rectal cancer responding to hepatic arterial infusion and systemic chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20031001

Can colorectal cancer patients with thymidylate synthase-overexpressing liver metastases have an overall survival advantage with hepatic arterial infusion alone?

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030915

5'-(2-Nitrophenylalkanoyl)-2'-deoxy-5-fluorouridines as potential prodrugs of FUDR for reductive activation.

Bioorganic & medicinal chemistry 20030901

Combination of TRAIL gene therapy and chemotherapy enhances antitumor and antimetastasis effects in chemosensitive and chemoresistant breast cancers.

Molecular therapy : the journal of the American Society of Gene Therapy 20030901

Phase I/II study of hepatic arterial therapy with floxuridine and dexamethasone in combination with intravenous irinotecan as adjuvant treatment after resection of hepatic metastases from colorectal cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030901

[PyNPase and DPD expression potentially predict response to 5'-DFUR treatment for node-positive breast cancer patients].

Gan to kagaku ryoho. Cancer & chemotherapy 20030901

Amino acid ester prodrugs of floxuridine: synthesis and effects of structure, stereochemistry, and site of esterification on the rate of hydrolysis.

Pharmaceutical research 20030901

[Doxifluridine for treatment of colorectal cancer].

Nihon rinsho. Japanese journal of clinical medicine 20030901

[Clinical evaluation of integration of transcatheter arterial chemoembolization and traditional Chinese medicine in treating metastatic liver cancer].

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20030901

Correlation between 5-fluorouracil metabolism and treatment response in two variants of C26 murine colon carcinoma.

British journal of cancer 20030818

MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.

The Journal of biological chemistry 20030808

Comparative study of purine and pyrimidine nucleoside analogues acting on the thymidylate kinases of Mycobacterium tuberculosis and of humans.

Chembiochem : a European journal of chemical biology 20030804

Multidetector CT arteriography with volumetric three-dimensional rendering to evaluate patients with metastatic colorectal disease for placement of a floxuridine infusion pump.

AJR. American journal of roentgenology 20030801

Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum.

Biochemical and biophysical research communications 20030801

[A case of multiple lung metastases of colon cancer with long-term survival following 5'-DFUR and cimetidine therapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20030801

Intraperitoneal therapy as consolidation for patients with ovarian cancer and negative reassessment after platinum-based chemotherapy.

Hematology/oncology clinics of North America 20030801

[Floxuridine-containing regime in the treatment of gestational trophoblastic tumor].

Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20030801

Pharmacokinetics of 5-fluorouracil following hepatic intra-arterial infusion in a VX2 hepatic metastasis model.

Japanese journal of clinical oncology 20030801

Functional analysis of the EWS/ETS target gene uridine phosphorylase.

Cancer research 20030715

A randomized controlled trial of postoperative adjuvant immunochemotherapy for colorectal cancer with oral medicines.

International journal of oncology 20030701

Adjuvant hepatic arterial chemotherapy following metastasectomy in patients with isolated liver metastases.

Annals of surgery 20030601

[A case of liver metastasis of colon cancer demonstrating complete remission with combination chemotherapy of 5'-DFUR and MMC].

Gan to kagaku ryoho. Cancer & chemotherapy 20030601

[Effect of preoperative oral 5'-DFUR on PyNPase level in gastrointestinal malignant tumor tissues].

Ai zheng = Aizheng = Chinese journal of cancer 20030601

[18F]5-fluoro-2-deoxyuridine-PET for imaging of malignant tumors and for measuring tissue proliferation.

Cancer biotherapy & radiopharmaceuticals 20030601

IPM chemotherapy in cytokine refractory renal cell cancer.

British journal of cancer 20030519

Hepatic artery chemotherapy and colorectal liver metastases.

Lancet (London, England) 20030517

Hepatic artery chemotherapy and colorectal liver mestastases.

Lancet (London, England) 20030517

[Evaluation of weekly paclitaxel and doxifluridine (5'-DFUR) combination therapy in patients with advanced or recurrent breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20030501

[Oral combination chemotherapy of 5'-deoxy-5-fluorouridine (furtulon) and cyclophosphamide for advanced breast cancer].

Zhonghua zhong liu za zhi [Chinese journal of oncology] 20030501

Formation of electrically active clusterized neural networks.

Physical review letters 20030425

Effects of introduction of dThdPase cDNA on sensitivity to 5'-deoxy-5-fluorouridine and tumor angiogenesis.

International journal of oncology 20030401

A 'combination oligonucleotide' antisense strategy to downregulate thymidylate synthase and decrease tumor cell growth and drug resistance.

Cancer gene therapy 20030401

Massive mucinous carcinoma of the breast untreated for 6 years.

International journal of clinical oncology 20030401

Preparation and characterization of chitosan microspheres containing doxifluridine.

Drug development and industrial pharmacy 20030401

Nonsteroidal anti-inflammatory drugs in colorectal cancer: from prevention to therapy.

British journal of cancer 20030324

Randomized controlled trial comparing oral doxifluridine plus oral cyclophosphamide with doxifluridine alone in women with node-positive breast cancer after primary surgery.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030315

Synthesis of 3'- and 5'-nitrooxy pyrimidine nucleoside nitrate esters: 'nitric oxide donor' agents for evaluation as anticancer and antiviral agents.

Journal of medicinal chemistry 20030313

Penetration of capecitabine and its metabolites into malignant and healthy tissues of patients with advanced breast cancer.

British journal of cancer 20030310

Population pharmacokinetics and concentration-effect relationships of capecitabine metabolites in colorectal cancer patients.

British journal of clinical pharmacology 20030301

Preclinical Auger and gamma radiation dosimetry for fluorodeoxyuridine-enhanced tumour proliferation scintigraphy with [123I]iododeoxyuridine.

European journal of nuclear medicine and molecular imaging 20030201

Subconjunctival doxifluridine administration suppresses rat choroidal neovascularization through activated thymidine phosphorylase.

Investigative ophthalmology & visual science 20030201

Hepatic artery infusion for liver metastases from colorectal cancer.

Lancet (London, England) 20030201

Oral doxifluridine plus leucovorin in metastatic colorectal cancer: randomized phase II trial with intravenous 5-fluorouracil plus leucovorin.

American journal of clinical oncology 20030201

[Optimal dosing schedule in combination therapy with irinotecan and doxifluridine in a human colorectal cancer xenograft model].

Gan to kagaku ryoho. Cancer & chemotherapy 20030201

[A case of advanced recurrent breast cancer responding to treatment with weekly docetaxel combined with doxorubicin].

Gan to kagaku ryoho. Cancer & chemotherapy 20030201

Effects of chlorin-mediated photodynamic therapy combined with fluoropyrimidines in vitro and in a patient.

Cancer chemotherapy and pharmacology 20030201

Laparoscopic radiofrequency ablation and hepatic artery infusion pump placement in the evolving treatment of colorectal hepatic metastases.

Surgical endoscopy 20030101

Detection of thymidylate synthase modulators by a novel screening assay.

Molecular pharmacology 20030101

The mechanism of action of radiosensitization of conventional chemotherapeutic agents.

Seminars in radiation oncology 20030101

Technical complications of continuous intra-arterial chemotherapy with 5-fluorodeoxyuridine and 5-fluorouracil for colorectal liver metastases.

Surgery 20030101

[The role of the regional (intra-arterial) chemotherapy in the treatment of hepatic metastases of colorectal cancer].

Medicina (Kaunas, Lithuania) 20030101

Recombinant leukocyte interferon, doxorubicin, and 5FUDR in patients with hepatocellular carcinoma-A phase II trial.

Journal of cancer research and clinical oncology 20030101

Depression of phenytoin metabolic capacity by 5-fluorouracil and doxifluridine in rats.

The Journal of pharmacy and pharmacology 20030101

In vitro studies on the immunosuppressive effect of 2',2'-difluorodeoxycytidine (dFdC) and its metabolite 2',2'-difluorodeoxyuridine (dFdU).

Immunobiology 20030101

Randomised double blind placebo control study of adjuvant treatment with the metalloproteinase inhibitor, Marimastat in patients with inoperable colorectal hepatic metastases: significant survival advantage in patients with musculoskeletal side-effects.

Anticancer research 20030101

Thymidine phosphorylase expressed in macrophages enhances antitumor effect of 5'-deoxy-5-fluorouridine on human colorectal carcinoma cells.

Anticancer research 20030101

Arterial chemotherapy as adjuvant and palliative treatment of hepatic colorectal metastases: an update.

Surgical oncology clinics of North America 20030101

Induction of thymidine phosphorylase expression by Taxol does not enhance Furtulon sensitivity in a cisplatin-resistant human ovarian carcinoma cell line.

Anticancer research 20030101

Totally implantable arterial device (TIAD): a questionable complication.

Hepato-gastroenterology 20030101

Thymidine phosphorylase expression correlates with malignant potential and anti-tumor effect of doxifluridine on gastric cancer: multivariate analysis for adjuvant chemotherapy doxifluridine vs. 5-fluorouracil.

Oncology reports 20030101

Clinical efficacy of doxifluridine and correlation to in vitro sensitivity of anticancer drugs in patients with colorectal cancer.

Anticancer research 20030101

Induction of thymidine phosphorylase expression and enhancement of Furtulon sensitivity by Taxol in a human ovarian carcinoma cell line.

Anticancer research 20030101

Hepatic artery embolization and chemoembolization for treatment of patients with metastatic carcinoid tumors: the M.D. Anderson experience.

Cancer journal (Sudbury, Mass.) 20030101

Design of Mycobacterium tuberculosis thymidine monophosphate kinase inhibitors.

Nucleosides, nucleotides & nucleic acids 20030101

A new class of Spiegelmers containing 2'-fluoro-nucleotides.

Nucleosides, nucleotides & nucleic acids 20030101

Synthesis and physicochemical characteristics of a liver-targeted conjugate of fluorodeoxyuridine monophosphate with lactosaminated human albumin.

Rapid communications in mass spectrometry : RCM 20030101

A case of chest wall recurrence of breast cancer treated with paclitaxel weekly, 5'-deoxy-5-fluorouridine, arterial embolization and chest wall resection.

Breast cancer (Tokyo, Japan) 20030101

Conformal chemoradiation for primary and metastatic liver malignancies.

Seminars in surgical oncology 20030101

Combination effects of Ara-C and 5-fluorodeoxyuridine against leukemia cells in vitro and in mice.

Anticancer research 20030101

Positive response to oral chemoendocrine combination therapy using 5'-deoxy-5-fluorouridine for locally advanced breast cancer with carcinomatous pleurisy: report of a case.

Surgery today 20030101

Induction chemotherapy followed by hyperfractionated radiotherapy with concurrent chemotherapy for locally advanced head and neck cancer.

Anticancer research 20030101

Bone morphogenetic protein-6 is a neurotrophic factor for calbindin-positive striatal neurons.

Journal of neuroscience research 20021201

Cytosolic and microsomal activation of doxifluridine and tegafur to produce 5-fluorouracil in human liver.

Cancer chemotherapy and pharmacology 20021201

Role of thymidine phosphorylase and dihydropyrimidine dehydrogenase in tumour progression and sensitivity to doxifluridine in gastric cancer patients.

European journal of cancer (Oxford, England : 1990) 20021201

Penetration of capecitabine and its metabolites into malignant and healthy tissue of patients with advanced breast cancer.

International journal of clinical pharmacology and therapeutics 20021201

Enhanced brain targeting by synthesis of 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine and incorporation into solid lipid nanoparticles.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20021101

External genital warts: diagnosis, treatment, and prevention.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20021015

Serotonergic stimulation of corticotropin-releasing hormone and pro-opiomelanocortin gene expression.

Journal of neuroendocrinology 20021001

[A case of colon metastasis to the lung treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR].

Gan to kagaku ryoho. Cancer & chemotherapy 20021001

[Phenomenon of pseudomutagenesis: experiments with modifiers of cell metabolism in human lymphocytes].

Genetika 20021001

Correlation of p53 immunostaining in primary and residual ovarian cancer at the time of positive second-look laparotomy and its prognostic role: a Southwest Oncology Group ancillary study.

Gynecologic oncology 20021001

Distribution of mutations in human thymidylate synthase yielding resistance to 5-fluorodeoxyuridine.

The Journal of biological chemistry 20020927

A 5-fluorodeoxyuridine prodrug as targeted therapy for prostate cancer.

Bioorganic & medicinal chemistry letters 20020902

[Chemotherapy of gastric cancer--a review of clinical trials in Japan].

Gan to kagaku ryoho. Cancer & chemotherapy 20020901

[A case of recurrent gastric cancer that responded dramatically to docetaxel and 5'-DFUR combination chemotherapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20020901

The means to an end of tumor cell resistance to chemotherapeutic drugs targeting thymidylate synthase: shoot the messenger.

Current drug targets 20020801

[A case of multiple skin metastases from gastric cancer successfully treated with docetaxel combined with doxifluridine].

Gan to kagaku ryoho. Cancer & chemotherapy 20020801

Comparison of 5-fluorouracil and 5-fluoro-2'-deoxyuridine as an effector in radiation-activated prodrugs.

Journal of chemotherapy (Florence, Italy) 20020801

Analysis of radiation-induced liver disease using the Lyman NTCP model.

International journal of radiation oncology, biology, physics 20020715

Quantification of 2'-fluoro-2'-deoxyuridine and 2'-fluoro-2'-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS.

Chemical research in toxicology 20020701

Searching limiting steps in the expression of chloroplast-encoded proteins: relations between gene copy number, transcription, transcript abundance and translation rate in the chloroplast of Chlamydomonas reinhardtii.

The Plant journal : for cell and molecular biology 20020701

[Assessment of complications in a randomized controlled study on multimodality therapy for patients following breast-conserving surgery: Kansai Breast Cancer Radiotherapy Research Group (5'-KBR)].

Gan to kagaku ryoho. Cancer & chemotherapy 20020701

[One case of locally advanced breast cancer in which multidisciplinary treatment, chiefly, therapy with preoperative intraarterial infusion of docetaxel (TXT), was successful].

Gan to kagaku ryoho. Cancer & chemotherapy 20020701

Expression of extracellular signal-regulated kinase and its relationship with clinicopathological characteristics of breast cancer.

Zhonghua zhong liu za zhi [Chinese journal of oncology] 20020701

Preoperative chemoradiation in patients with resectable rectal cancer: results on tumor response.

Annals of surgical oncology 20020601

[A case of colon cancer with multiple liver metastases and lymph nodes metastases successfully treated by 5'-deoxy-5-fluorouridine].

Gan to kagaku ryoho. Cancer & chemotherapy 20020601

Floxuridine coupling with lactosaminated human albumin to increase drug efficacy on liver micrometastases.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20020601

Conjugates of nucleoside analogs with lactosaminated human albumin to selectively increase the drug levels in liver blood: requirements for a regional chemotherapy.

The Journal of pharmacology and experimental therapeutics 20020501

Probable metabolic interaction of doxifluridine with phenytoin.

The Annals of pharmacotherapy 20020501

[A case of breast cancer with multiple bone metastases that responded remarkably to doxifluridine (5'-DFUR), cyclophosphamide (CPA), medroxyprogesterone acetate (MPA) and pamidronate disodium therapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20020501

[The antitumor activity of DPD inhibitory-fluoropyrimidine (DIF) and non-DIF alone or in combination with paclitaxel against orthotopically implanted human breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20020501

Metastatic urothelial cancer showing an efficacy by low-dose cisplatin.

International journal of urology : official journal of the Japanese Urological Association 20020501

Thymidine phosphorylase activity in renal cell carcinoma: relationship between histological parameters and chemosensitivity to fluorouracil-related drugs.

Urological research 20020501

Covalent analogues of DNA base-pairs and triplets. Part 2: synthesis and cytostatic activity of bis(purin-6-yl)acetylenes,-diacetylenes and related compounds.

Bioorganic & medicinal chemistry letters 20020408

Impact of the oxaliplatin-5 fluorouracil-folinic acid combination on respective intracellular determinants of drug activity.

British journal of cancer 20020408

Downstaging of hepatocellular carcinoma and liver metastases from colorectal cancer by selective intra-arterial chemotherapy.

Surgery 20020401

Intrahepatic arterial infusion of chemotherapy: pharmacologic principles.

Seminars in oncology 20020401

Intrahepatic arterial infusion of chemotherapy: clinical results.

Seminars in oncology 20020401

[A case report of effective chemoradiation with 5'-DFUR and concomitant preoperative radiotherapy of the lower rectum].

Gan to kagaku ryoho. Cancer & chemotherapy 20020401

Prognostic and predictive value of thymidine phosphorylase activity in early-stage breast cancer patients.

Clinical breast cancer 20020401

Combined-modality treatment for resectable metastatic colorectal carcinoma to the liver: surgical resection of hepatic metastases in combination with continuous infusion of chemotherapy--an intergroup study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020315

Echogenicity of liver metastases from colorectal carcinoma is an independent prognostic factor in patients treated with regional chemotherapy.

Cancer 20020315

The effect of adjuvant 5'-deoxy-5-fluorouridine in early stage breast cancer patients: results from a multicenter randomized controlled trial.

International journal of oncology 20020301

Fighting wars, winning battles.

Annals of surgical oncology 20020301

Systemic irinotecan and regional floxuridine after hepatic cytoreduction in 185 patients with unresectable colorectal cancer metastases.

Annals of surgical oncology 20020301

[Successful treatment of advanced recurent breast cancer using DMpC therapy as maintenance therapy].

Gan to kagaku ryoho. Cancer & chemotherapy 20020301

Overexpression of pyrimidine nucleoside phosphorylase enhances the sensitivity to 5'-deoxy-5-fluorouridine in tumour cells in vitro and in vivo.

European journal of cancer (Oxford, England : 1990) 20020301

A phase II study of doxifluridine in elderly patients with advanced gastric cancer: the Japan Clinical Oncology Group Study (JCOG 9410).

Japanese journal of clinical oncology 20020301

Biochemical and molecular effects of UCN-01 in combination with 5-fluorodeoxyuridine in A431 human epidermoid cancer cells.

Anti-cancer drugs 20020301

CT-guided intratumoural administration of cisplatin/epinephrine gel for treatment of malignant liver tumours.

British journal of cancer 20020212

[Evidence for and practical use of arterial infusion chemotherapy for liver metastases].

Gan to kagaku ryoho. Cancer & chemotherapy 20020201

[A case of long surviving advanced recurrent breast cancer with multiple bone metastases responding to treatment with 5'-DFUR combined with MPA].

Gan to kagaku ryoho. Cancer & chemotherapy 20020201

A controlled 'before-after' study: impact of a clinical guidelines programme and regional cancer network organization on medical practice.

British journal of cancer 20020201

Sciatic conditioned medium increases survival, proliferation and differentiation of retinal cells in culture.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20020201

Thymidylate Synthase expression as a predictor of clinical response to fluoropyrimidine-based chemotherapy in advanced colorectal cancer.

Cancer treatment reviews 20020201

Immunohistochemical variation of human equilibrative nucleoside transporter 1 protein in primary breast cancers.

Clinical cancer research : an official journal of the American Association for Cancer Research 20020101

Use of 5-[(76)Br]bromo-2'-fluoro-2'-deoxyuridine as a ligand for tumour proliferation: validation in an animal tumour model.

European journal of nuclear medicine and molecular imaging 20020101

[A 5'-DFUR + CPA + THP therapy that was effective for paclitaxel-refractory pulmonary metastasis of breast cancer--a case report].

Gan to kagaku ryoho. Cancer & chemotherapy 20020101

[Adjuvant chemotherapy after curative resection for gastric cancer-5'-DFUR + cisplatin vs 5'-DFUR].

Gan to kagaku ryoho. Cancer & chemotherapy 20020101

[Antimetastatic and antitumor effects of fluoropyrimidines alone and combined with taxanes in a murine model of breast cancer metastatic to the lung].

Gan to kagaku ryoho. Cancer & chemotherapy 20020101

Treatment of patients with superficial bladder cancer by intravesical instillation of anticancer drugs plus oral chemotherapy following TUR-Bt: a randomized controlled trial.

Oncology reports 20020101

Thymidine phosphorylase and dihydropyrimidine dehydrogenase levels in primary colorectal cancer show a relationship to clinical effects of 5'-deoxy-5-fluorouridine as adjuvant chemotherapy.

Oncology reports 20020101

Circadian chemotherapy for gynecological and genitourinary cancers.

Chronobiology international 20020101

Schedule-selective biochemical modulation of 5-fluorouracil in advanced colorectal cancer--a phase II study.

BMC cancer 20020101

Neoadjuvant chemotherapy with CPT-11 and cisplatin downstages locally advanced gastric cancer.

Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20020101

Percutaneous vs. surgical placement of hepatic artery indwelling catheters for regional chemotherapy.

Hepato-gastroenterology 20020101

Isolation perfusion of the liver.

Cancer journal (Sudbury, Mass.) 20020101

Postoperative adjuvant chemotherapy is effective in gastric cancer with serosal invasion: significance in patients chosen for multivariate analysis.

Oncology reports 20020101

Hepatic artery infusion of chemotherapy as a treatment for hepatic metastases from colorectal cancer.

Cancer journal (Sudbury, Mass.) 20020101

Combined surgical-percutaneous approach for placement of arterial devices for hepatic chemotherapy.

Hepato-gastroenterology 20020101

Prolonged exposure of chromaffin cells to nitric oxide down-regulates the activity of soluble guanylyl cyclase and corresponding mRNA and protein levels.

BMC biochemistry 20020101

Potent antitumor effect of 1-(2-deoxy-2-fluoro-4-thio-beta-D-arabinofuranosyl)cytosine on peritoneal dissemination models of gastrointestinal cancers.

Oncology reports 20020101

Efficient intracellular delivery of 5-fluorodeoxyuridine into colon cancer cells by targeted immunoliposomes.

Cancer detection and prevention 20020101

Effectiveness of doxifluridine (5'-DFUR)/docetaxel against advanced/recurrent gastric cancer showing resistance to various anticancer drug regimens.

Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association 20020101

IFN gamma-induced up-regulation of PD-ECGF/TP enhances the cytotoxicity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in bladder cancer cells.

Anticancer research 20020101

[Reorganization of DNA replicating system induced by 5-fluorodeoxyuridine and caffeine as the basis for radiosensitivity in human calls].

Tsitologiia 20020101

Comparative antitumor activity of 5-fluorouracil and 5'-deoxy-5-fluorouridine in combination with interferon gamma in renal cell carcinoma cell lines.

Anticancer research 20020101

[Impact of preoperative locoregional chemotherapy with fluorodeoxyuridine on the outcome of liver resection].

Chirurgia italiana 20020101

Mechanisms of cell death induced by 5-fluoro-2'-deoxyuridine (FUdR)--necrosis or apoptosis after treated with FUdR.

Nucleic acids research. Supplement (2001) 20020101

Synthesis and biological studies of novel nucleoside phosphoramidate prodrugs.

Journal of medicinal chemistry 20011206

Antisense-induced down-regulation of thymidylate synthase and enhanced cytotoxicity of 5-FUdR in 5-FUdR-resistant HeLa cells.

British journal of pharmacology 20011201

Regional chemotherapy of nonresectable colorectal liver metastases with mitoxantrone, 5-fluorouracil, folinic acid, and mitomycin C may prolong survival.

Cancer 20011201

Surgery as adjuvant therapy? The treatment of peritoneal metastases from gastrointestinal malignancy.

Annals of surgical oncology 20011201

Surgical debulking and intraperitoneal chemotherapy for established peritoneal metastases from colon and appendix cancer.

Annals of surgical oncology 20011201

Randomised trial of SIR-Spheres plus chemotherapy vs. chemotherapy alone for treating patients with liver metastases from primary large bowel cancer.

Annals of oncology : official journal of the European Society for Medical Oncology 20011201

Amino acid phosphoramidate nucleosides: potential ADEPT/GDEPT substrates.

Bioorganic & medicinal chemistry letters 20011105

Acquisition of human concentrative nucleoside transporter 2 (hcnt2) activity by gene transfer confers sensitivity to fluoropyrimidine nucleosides in drug-resistant leukemia cells.

Molecular pharmacology 20011101

Fluorodeoxyuridine improves imaging of human glioblastoma xenografts with radiolabeled iododeoxyuridine.

Cancer research 20011101

P53 mutation and response to hepatic arterial floxuridine in patients with colorectal liver metastases.

Journal of cancer research and clinical oncology 20011101

Plasma, intestine and tumor levels of 5-fluorouracil in mice bearing L1210 ascites tumor following oral administration of 5-fluorouracil, UFT (mixed compound of tegafur and uracil), carmofur and 5'-deoxy-5-fluorouridine.

Biological & pharmaceutical bulletin 20011101

[Hepatic infusion of docetaxel using PEIT for a patient with stage IV breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20011101

[A case of lung metastasis from colon cancer treated successfully with combined chemotherapy of CPT-11 and 5'-DFUR].

Gan to kagaku ryoho. Cancer & chemotherapy 20011101

Survival benefits of adjuvant chemotherapy with oral doxifluridine (5'-DFUR) following radiotherapy in patients with unresectable pancreatic cancer.

Journal of surgical oncology 20011101

Thymidylate synthase pharmacogenetics in colorectal cancer.

Clinical colorectal cancer 20011101

Thymidine phosphorylase expression is useful in selecting adjuvant chemotherapy for stage III gastric cancer.

International journal of oncology 20011001

[A patient with recurrent breast cancer whose liver metastasis regressed following combined use of weekly docetaxel and MPA.5'-DFUR].

Gan to kagaku ryoho. Cancer & chemotherapy 20011001

[Effect of peroral doxifluridine plus hepatic arterial infusion for synchronous liver metastasis of colorectal cancer--correlation with the expression of thymidine phosphorylase and dihydropyrimidine dehydrogenase in primary colorectal cancer lesions].

Gan to kagaku ryoho. Cancer & chemotherapy 20011001

Combined effects of docetaxel and fluoropyrimidines on tumor growth and expression of interleukin-6 and thymidine phosphorylase in breast cancer xenografts.

Cancer chemotherapy and pharmacology 20011001

Interaction of thymidylate synthase with the 5'-thiophosphates, 5'-dithiophosphates, 5'-H-phosphonates and 5'-S-thiosulfates of 2'-deoxyuridine, thymidine and 5-fluoro-2'-deoxyuridine.

Biological chemistry 20011001

[Study on brain targeting 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine pharmacosomes].

Yao xue xue bao = Acta pharmaceutica Sinica 20011001

Inhibition of thymidylate synthase activity by antisense oligodeoxynucleotide and possible role in thymineless treatment.

Molecular pharmacology 20010901

Three-dimensional organization of the hepatic microvasculature in hereditary hemorrhagic telangiectasia.

Archives of pathology & laboratory medicine 20010901

Variations in 5-fluorouracil concentrations of colorectal tissues as compared with dihydropyrimidine dehydrogenase (DPD) enzyme activities and DPD messenger RNA levels.

Clinical cancer research : an official journal of the American Association for Cancer Research 20010901

[Combination chemotherapy of doxifluridine plus mitomycin C for colorectal lung metastasis--phase II study].

Gan to kagaku ryoho. Cancer & chemotherapy 20010901

Docetaxel alone or orally combined with 5-fluorouracil and its derivatives: effects on mouse mammary tumor cell line MM2 in vitro and in vivo.

Anti-cancer drugs 20010901

Impact of thymidine phosphorylase surexpression on fluoropyrimidine activity and on tumour angiogenesis.

British journal of cancer 20010801

Role of Bax in apoptosis of IL-3-dependent cells.

Oncogene 20010727

Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.

Cancer research 20010701

Phase I and pharmacologic study of i.v. hydroxyurea infusion given with i.p. 5-fluoro-2'-deoxyuridine and leucovorin.

Anti-cancer drugs 20010701

[A phase I study of docetaxel (TXT) and doxifluridine (5'-DFUR) combination therapy in patients with advanced and recurrent breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20010701

[The efficacy of combination chemotherapy of 5'-deoxy-5-fluorouridine (5'-DFUR), cyclophosphamide (CPA) and medroxyprogesterone acetate (MPA) for bone metastasis in breast cancer patients].

Gan to kagaku ryoho. Cancer & chemotherapy 20010701

Role of the human concentrative nucleoside transporter (hCNT1) in the cytotoxic action of 5[Prime]-deoxy-5-fluorouridine, an active intermediate metabolite of capecitabine, a novel oral anticancer drug.

Molecular pharmacology 20010601

Preoperative chemoradiotherapy with oral doxifluridine plus low-dose oral leucovorin in unresectable primary rectal cancer.

International journal of radiation oncology, biology, physics 20010601

Intracavitary chemotherapy with 5-fluoro-2'-deoxyuridine (FdUrd) in malignant brain tumors.

Japanese journal of clinical oncology 20010601

[Optimization of the preparation of 3',5'-dioctanoyl-5-fluoro-2'-deoxyuridine pharmacosomes using central composite design].

Yao xue xue bao = Acta pharmaceutica Sinica 20010601

Phase I study of hepatic arterial infusion of floxuridine and dexamethasone with systemic irinotecan for unresectable hepatic metastases from colorectal cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20010515

In vivo evaluation of 5-[(18)F]fluoro-2'-deoxyuridine as tracer for positron emission tomography in a murine pancreatic cancer model.

Cancer research 20010515

Enhancement of sensitivity to capecitabine in human renal carcinoma cells transfected with thymidine phosphorylase cDNA.

International journal of cancer 20010501

Renal cell carcinoma.

Current opinion in oncology 20010501

Sequential intrahepatic and systemic fluoropyrimidine-based chemotherapy for metastatic colorectal cancer confined to the liver. A phase II study.

Cancer chemotherapy and pharmacology 20010501

Systemic irinotecan or regional floxuridine chemotherapy prolongs survival after hepatic cryosurgery in patients with metastatic colon cancer refractory to 5-fluorouracil.

Clinical colorectal cancer 20010501

Vaccinia virus inhibitors as a paradigm for the chemotherapy of poxvirus infections.

Clinical microbiology reviews 20010401

Progression and enhancement of metastatic potential after exposure of tumor cells to chemotherapeutic agents.

Cancer research 20010401

Thymidine kinase, thymidylate synthase, and dihydropyrimidine dehydrogenase profiles of cell lines of the National Cancer Institute's Anticancer Drug Screen.

Clinical cancer research : an official journal of the American Association for Cancer Research 20010401

Schedule dependency of antitumor activity in combination therapy with capecitabine/5'-deoxy-5-fluorouridine and docetaxel in breast cancer models.

Clinical cancer research : an official journal of the American Association for Cancer Research 20010401

[Preoperative chemotherapy for advanced colorectal carcinomas--comparison of histological effect between 5'-DFUR + leucovorin tablet and 5'-DFUR alone].

Gan to kagaku ryoho. Cancer & chemotherapy 20010401

Therapeutic approaches to metastasis confined to the liver.

Current oncology reports 20010301

Coupling of 5-fluoro 2'-deoxyuridine to lactosaminated poly-l-lysine: an approach to a regional, non-invasive chemotherapy of liver micrometastases.

Biochemical pharmacology 20010215

Isolated hepatic perfusion for unresectable hepatic metastases from colorectal cancer.

Surgery 20010201

Combination of standard cytotoxic agents with polyamine analogues in the treatment of breast cancer cell lines.

Clinical cancer research : an official journal of the American Association for Cancer Research 20010201

[Weekly low dose CPT-11 for multiple lung metastases of colon cancer on an out-patient treatment: a case report].

Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20010201

[Clinical evaluation of effects and improvement in quality of life from palliative therapy of combination chemotherapy with Furtulon and consecutive low-dose cisplatin in cases of unresectable advanced gastrointestinal carcinoma].

Gan to kagaku ryoho. Cancer & chemotherapy 20010201

[Advanced breast cancer with multiple bone metastases successfully treated with combined chemoendocrine-therapy of CEF (cyclophosphamide, epirubicin, 5-fluorouracil) and 5'-DFUR (5'-deoxy-5-fluorouridine) + MPA (medroxyprogesterone acetate)--a case report].

Gan to kagaku ryoho. Cancer & chemotherapy 20010201

Creation and characterization of 5-fluorodeoxyuridine-resistant Arg50 loop mutants of human thymidylate synthase.

Cancer research 20010115

Apoptosis of haematopoietic cells upon thymidylate synthase inhibition is independent of p53 accumulation and CD95-CD95 ligand interaction.

The Biochemical journal 20010101

The significance of thymidine phosphorylase expression in colorectal cancer.

Oncology reports 20010101

Reduced cellular transport and activation of fluoropyrimidine nucleosides and resistance in human lymphocytic cell lines selected for arabinosylcytosine resistance.

Biochemical pharmacology 20010101

5'-deoxy-5-fluorouridine, medroxyprogestrone acetate and mitoxantrone hydrochloride for advanced or recurrent breast cancer.

Breast cancer (Tokyo, Japan) 20010101

Prognostic value of thymidine phosphorylase immunostaining in patients with uterine cervical cancer treated concurrently with doxifluridine, radiotherapy and immunotherapy.

Oncology reports 20010101

Effects of concomitant use of doxifluridine, radiotherapy and immunotherapy in patients with advanced cervical cancer.

Oncology reports 20010101

[Effectiveness of high-dose, intermittent 5'-DFUR therapy for advanced gastric cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20010101

[Survival of 2 years and 7 months with 5'-DFUR treatment in a patient with peritoneal gastric cancer recurrence].

Gan to kagaku ryoho. Cancer & chemotherapy 20010101

Intravenous 5-fluorouracil versus oral doxifluridine as preoperative concurrent chemoradiation for locally advanced rectal cancer: prospective randomized trials.

Japanese journal of clinical oncology 20010101

A phase II trial of mitomycin C, 5'-deoxy-5-fluorouridine, etoposide and medroxyprogesterone acetate (McVD-MPA) as a salvage chemotherapy to anthracycline-resistant tumor in relapsed breast cancer and its mechanism(s) of antitumor action.

Oncology reports 20010101

Locoregional therapy for liver metastases from colorectal cancer: the possibilities of intraarterial chemotherapy, and new hepatic-directed modalities.

Hepato-gastroenterology 20010101

Thymidine phosphorylase expression and effect of doxifluridine: a phase II study.

Oncology reports 20010101

Bone morphogenetic protein-2, but not bone morphogenetic protein-7, promotes dendritic growth and calbindin phenotype in cultured rat striatal neurons.

Neuroscience 20010101

A randomized study comparing oral and standard regimens for metastatic breast cancer.

Oncology reports 20010101

Extrahepatic biliary stenoses after hepatic arterial infusion (HAI) of floxuridine (FUdR) for liver metastases from colorectal cancer.

Hepato-gastroenterology 20010101

Malnutrition and cachexia in ovarian cancer patients: pathophysiology and management.

Anticancer research 20010101

gamma-Hydroxybutyric acid and 5-fluorouracil, metabolites of UFT, inhibit the angiogenesis induced by vascular endothelial growth factor.

Angiogenesis 20010101

Complications of hepatic artery infusion: a review of 4580 reported cases.

International journal of gastrointestinal cancer 20010101

Synthesis and antitumor activities of novel pyrimidine derivatives of 2,3-O,O-dibenzyl-6-deoxy-L-ascorbic acid and 4,5-didehydro-5,6- dideoxy-L-ascorbic acid.

Journal of medicinal chemistry 20001214

[A case of effective bisphosphonate therapy of sequential pamidronate and incadronate for bone metastases from breast cancer].

Gan to kagaku ryoho. Cancer & chemotherapy 20000801

A rapid phenotypic assay for detection of acyclovir-resistant varicella-zoster virus with mutations in the thymidine kinase open reading frame.

Antimicrobial agents and chemotherapy 20000401

[Pain relief with alendronate therapy in a breast cancer patient with bone metastasis].

Gan to kagaku ryoho. Cancer & chemotherapy 20000401

Antisense down-regulation of thymidylate synthase to suppress growth and enhance cytotoxicity of 5-FUdR, 5-FU and Tomudex in HeLa cells.

British journal of pharmacology 19990801

Anti-herpesvirus activities and cytotoxicities of 2-thiopyrimidine nucleoside analogues in vitro.

Antiviral chemistry & chemotherapy 19990701

Suppression of replication of multidrug-resistant HIV type 1 variants by combinations of thymidylate synthase inhibitors with zidovudine or stavudine.

Molecular pharmacology 19990301

Alternating floxuridine and 5-fluorouracil hepatic arterial chemotherapy for colorectal liver metastases minimizes biliary toxicity.

American journal of surgery 19960901

Use of floxuridine to modulate the antiviral activity of zidovudine.

AIDS research and human retroviruses 19960720

2',3'-Didehydro-3'-deoxythymidine: regulation of its metabolic activation by modulators of thymidine-5'-triphosphate biosynthesis.

Molecular pharmacology 19960701

Epigenetic mechanisms of drug resistance: drug-induced DNA hypermethylation and drug resistance.

Proceedings of the National Academy of Sciences of the United States of America 19930401

The effects on toxicity of circadian patterning of continuous hepatic artery infusion.

HPB surgery : a world journal of hepatic, pancreatic and biliary surgery 19920101

Synthesis and anticancer and antiviral activities of various 2'- and 3'-methylidene-substituted nucleoside analogues and crystal structure of 2'-deoxy-2'-methylidenecytidine hydrochloride.

Journal of medicinal chemistry 19910801

Hepatobiliary toxicity of 5-fluoro-2'-deoxyuridine. Intra-arterial versus portal venous routes of infusion.

Investigative radiology 19910501

Complications of hepatic arterial infusion chemotherapy.

Radiographics : a review publication of the Radiological Society of North America, Inc 19910101

Fatty liver change as a result of hepatic artery infusion chemotherapy.

American journal of clinical oncology 19900401

Venoocclusive lesions of the central veins and portal vein radicles secondary to intraarterial 5-fluoro-2'-deoxyuridine infusion.

Human pathology 19891201

Toxoplasma gondii: the biochemical basis of resistance to emimycin.

Experimental parasitology 19890801

Floxuridine-induced sclerosing cholangitis: an ischemic cholangiopathy?

Hepatology (Baltimore, Md.) 19890201

[Computed tomographic and angiographic studies of arterial liver perfusion following intra-arterial infusion chemotherapy using 5-fluoro-2-deoxyuridine].

Rontgen-Blatter; Zeitschrift fur Rontgen-Technik und medizinisch-wissenschaftliche Photographie 19890201

Mutants of human colon adenocarcinoma, selected for thymidylate synthase deficiency.

Proceedings of the National Academy of Sciences of the United States of America 19890201

Floxuridine-associated sclerosing cholangitis. A dog model.

Investigative radiology 19890101

Intra-arterial hepatic chemotherapy for metastatic liver from colo-rectal carcinoma origin.

Selective cancer therapeutics 19890101

[Biliary and arterial obstructive processes in regional chemotherapy with FUDR].

RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 19881101

Effects of various nucleosides on antiviral activity and metabolism of 1-beta-D-arabinofuranosyl-E-5-(2-bromovinyl)uracil against herpes simplex virus types 1 and 2.

Antimicrobial agents and chemotherapy 19881001

Drug-induced cholestasis.

Bailliere's clinical gastroenterology 19880401

Nonspecific corticosteroid therapy in patients receiving intra-arterial chemotherapy for hepatic metastases of colorectal origin.

Cancer investigation 19880101

2'-Fluorinated arabinonucleosides of 5-(2-haloalkyl)uracil: synthesis and antiviral activity.

Journal of medicinal chemistry 19870701

In vitro and in vivo antiviral activity of 2'-fluorinated arabinosides of 5-(2-haloalkyl)uracil.

Antiviral research 19870601

Bile duct strictures associated with hepatic arterial infusion chemotherapy.

Gastrointestinal radiology 19870101

Sclerosing cholangitis from intraarterial floxuridine.

Journal of clinical gastroenterology 19861201

Fatal liver cirrhosis associated with long-term arterial infusion of floxuridine.

Lancet (London, England) 19861115

Hepatic arterial infusion with floxuridine and cisplatin: overriding importance of antitumor effect versus degree of tumor burden as determinants of survival among patients with colorectal cancer.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19860901

Synthesis and antitumor and antiviral properties of 5-halo- and 5-(trifluoromethyl)-2'-deoxyuridine 3',5'-cyclic monophosphates and neutral triesters.

Journal of medicinal chemistry 19860701

Phase II clinical evaluation of doxifluridine.

Cancer treatment reports 19860601

Wernicke-Korsakoff-like syndrome in patients with colorectal carcinoma treated with high-dose doxifluridine (5'-dFUrd).

Acta neurologica Scandinavica 19860501

Sclerosing cholangitis associated with hepatic arterial FUDR chemotherapy: radiographic-histologic correlation.

AJR. American journal of roentgenology 19860401

Cholecystitis secondary to infusion chemotherapy.

Journal of surgical oncology 19860401

Chemical cholecystitis after intrahepatic chemotherapy. The case for prophylactic cholecystectomy during pump placement.

Diseases of the colon and rectum 19860301

Interaction of monoclonal antibodies directed against bromodeoxyuridine with pyrimidine bases, nucleosides, and DNA.

Journal of immunology (Baltimore, Md. : 1950) 19860301

[Sclerosing cholangitis after chemotherapy by continuous hepatic intra-arterial infusion of fluorodeoxyuridine].

Gastroenterologie clinique et biologique 19860201

Biliary sclerosis associated with hepatic artery infusion of floxuridine.

Surgery 19860101

Common duct stricture associated with hepatic artery infusion of FUDR.

Journal of surgical oncology 19860101

Neurologic toxicity associated with hepatic artery infusion HAI of FUdR.

Cancer chemotherapy and pharmacology 19860101

Acute cholecystitis associated with hepatic arterial infusion of floxuridine.

American journal of surgery 19851201

Hepatic artery infusion chemotherapy for colorectal metastases: a personal experience.

Journal of surgical oncology 19851101

Enhanced inhibition of thymidylate synthase by methotrexate polyglutamates.

The Journal of biological chemistry 19850815

Neurological manifestations in a phase 2 study of 13 patients treated with doxyfluridine.

Acta neurologica Scandinavica 19850801

Iatrogenic sclerosing cholangitis following hepatic arterial chemotherapy infusion.

Radiology 19850801

Cholangitis complicating intraarterial chemotherapy in liver metastasis.

Radiology 19850801

Hepatobiliary scintigraphy in patients receiving hepatic artery infusion chemotherapy.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 19850501

Doxifluridine (5'-dFUrd) in patients with advanced colorectal carcinoma. A phase II study.

Cancer chemotherapy and pharmacology 19850101

Nucleic acid related compounds. 47. Synthesis and biological activities of pyrimidine and purine 'acyclic' nucleoside analogues.

Journal of medicinal chemistry 19841101

Chemical cholecystitis associated with hepatic artery infusion chemotherapy.

AJR. American journal of roentgenology 19831001

Antiherpes activity of (E)-5-(2-bromovinyl)- and 5-vinyl-1-beta-D-arabinofuranosyluracil and some other 5-substituted uracil arabinosyl nucleosides in two different cell lines.

Antiviral research 19830901

Long-term hepatic arterial infusion of 5-fluorodeoxyuridine for liver metastases using an implantable infusion pump.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19830501

Carbocyclic analogues of 5-substituted uracil nucleosides: synthesis and antiviral activity.

Journal of medicinal chemistry 19830201

Synthesis and antiviral activity of 5-[(cyanomethylene)oxy]-2'-deoxyuridine.

Journal of medicinal chemistry 19810401

Improved synthesis and in vitro antiviral activities of 5-cyanouridine and 5-cyano-2'-deoxyuridine.

Journal of medicinal chemistry 19770701

Bioassay of alkyl halides and nucleotide base analogs by pulmonary tumor response in strain A mice.

Cancer research 19750601

Nucleosides. 3. Studies on 5-methylamino-2'-deoxyuridine as a specific antiherpes agent.

Journal of medicinal chemistry 19660501