Home Other Building Blocks Cyproconazole

Cyproconazole

CAS No.:
94361-06-5
Catalog Number:
AG0035UW
Molecular Formula:
C15H18ClN3O
Molecular Weight:
291.7759
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%(HPLC)
In Stock USA
United States
$46
- +
25mg
98%(HPLC)
In Stock USA
United States
$68
- +
100mg
98%(HPLC)
In Stock USA
United States
$151
- +
Product Description
Catalog Number:
AG0035UW
Chemical Name:
Cyproconazole
CAS Number:
94361-06-5
Molecular Formula:
C15H18ClN3O
Molecular Weight:
291.7759
MDL Number:
MFCD01678672
IUPAC Name:
2-(4-chlorophenyl)-3-cyclopropyl-1-(1,2,4-triazol-1-yl)butan-2-ol
InChI:
InChI=1S/C15H18ClN3O/c1-11(12-2-3-12)15(20,8-19-10-17-9-18-19)13-4-6-14(16)7-5-13/h4-7,9-12,20H,2-3,8H2,1H3
InChI Key:
UFNOUKDBUJZYDE-UHFFFAOYSA-N
SMILES:
CC(C(c1ccc(cc1)Cl)(Cn1ncnc1)O)C1CC1
Properties
Complexity:
331  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
291.114g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
291.779g/mol
Monoisotopic Mass:
291.114g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
50.9A^2
Undefined Atom Stereocenter Count:
2  
Undefined Bond Stereocenter Count:
0
XLogP3:
2.9  
Literature
Title Journal
Adverse Outcome Pathway-Driven Analysis of Liver Steatosis in Vitro: A Case Study with Cyproconazole. Chemical research in toxicology 20180820
Mixture effects of two plant protection products in liver cell lines. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180201
Hepatotoxic combination effects of three azole fungicides in a broad dose range. Archives of toxicology 20180101
Hepatotoxic effects of cyproconazole and prochloraz in wild-type and hCAR/hPXR mice. Archives of toxicology 20170801
Mixture effects of azole fungicides on the adrenal gland in a broad dose range. Toxicology 20170615
Combination effects of azole fungicides in male rats in a broad dose range. Toxicology 20160429
Hepatotoxic effects of (tri)azole fungicides in a broad dose range. Archives of toxicology 20151101
Grouping of histone deacetylase inhibitors and other toxicants disturbing neural crest migration by transcriptional profiling. Neurotoxicology 20150901
Involvement of constitutive androstane receptor in liver hypertrophy and liver tumor development induced by triazole fungicides. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20150401
Identification of chemical modulators of the constitutive activated receptor (CAR) in a gene expression compendium. Nuclear receptor signaling 20150101
Combination effects of (tri)azole fungicides on hormone production and xenobiotic metabolism in a human placental cell line. International journal of environmental research and public health 20140901
Concordance of transcriptional and apical benchmark dose levels for conazole-induced liver effects in mice. Toxicological sciences : an official journal of the Society of Toxicology 20131101
Dose-response involvement of constitutive androstane receptor in mouse liver hypertrophy induced by triazole fungicides. Toxicology letters 20130731
Triazole-induced gene expression changes in the zebrafish embryo. Reproductive toxicology (Elmsford, N.Y.) 20120901
Triazole induced concentration-related gene signatures in rat whole embryo culture. Reproductive toxicology (Elmsford, N.Y.) 20120901
Toxicity assessment of 45 pesticides to the epigeic earthworm Eisenia fetida. Chemosphere 20120701
The hepatocarcinogenic conazoles: cyproconazole, epoxiconazole, and propiconazole induce a common set of toxicological and transcriptional responses. Toxicological sciences : an official journal of the Society of Toxicology 20120501
Environmental fate of fungicides in surface waters of a horticultural-production catchment in southeastern Australia. Archives of environmental contamination and toxicology 20120401
HPLC-MS/MS enantioseparation of triazole fungicides using polysaccharide-based stationary phases. Journal of separation science 20120401
Transcriptomic concentration-response evaluation of valproic acid, cyproconazole, and hexaconazole in the neural embryonic stem cell test (ESTn). Toxicological sciences : an official journal of the Society of Toxicology 20120201
Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus. PloS one 20120101
Residues behavior of some fungicides applied on two greenhouse tomato varieties different in shape and weight. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101
Text mining for literature review and knowledge discovery in cancer risk assessment and research. PloS one 20120101
Is the amphibian X. laevis WEC a good alternative method to rodent WEC teratogenicity assay? The example of the three triazole derivative fungicides Triadimefon, Tebuconazole, Cyproconazole. Reproductive toxicology (Elmsford, N.Y.) 20110901
Chemical class-specific gene expression changes in the zebrafish embryo after exposure to glycol ether alkoxy acids and 1,2,4-triazole antifungals. Reproductive toxicology (Elmsford, N.Y.) 20110901
Comparison of the mouse Embryonic Stem cell Test, the rat Whole Embryo Culture and the Zebrafish Embryotoxicity Test as alternative methods for developmental toxicity testing of six 1,2,4-triazoles. Toxicology and applied pharmacology 20110601
Determination of azoles in sewage sludge from Spanish wastewater treatment plants by liquid chromatography-tandem mass spectrometry. Journal of separation science 20110601
Relative embryotoxicity of two classes of chemicals in a modified zebrafish embryotoxicity test and comparison with their in vivo potencies. Toxicology in vitro : an international journal published in association with BIBRA 20110401
Degradation of glyphosate in soil photocatalyzed by Fe3O4/SiO2/TiO2 under solar light. International journal of environmental research and public health 20110401
Activity profiles of 309 ToxCast™ chemicals evaluated across 292 biochemical targets. Toxicology 20110328
Using nuclear receptor activity to stratify hepatocarcinogens. PloS one 20110101
Occurrence and removal of fungicides in municipal sewage treatment plant. Journal of hazardous materials 20100315
Fungicide dissipation and impact on metolachlor aerobic soil degradation and soil microbial dynamics. The Science of the total environment 20100215
Simultaneous enantioseparation of cyproconazole, bromuconazole, and diniconazole enantiomers by CD-modified MEKC. Electrophoresis 20090601
In vitro toxicity of selected fungicides from the groups of benzimidazoles and demethylation inhibitors to Cladobotryum dendroides and Agaricus bisporus. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20090501
The effect of fungicides on seed yield and disease control in Italian ryegrass. Communications in agricultural and applied biological sciences 20090101
Development of monoclonal immunoassays for the determination of triazole fungicides in fruit juices. Journal of agricultural and food chemistry 20081008
Photocatalytic degradation of pesticides in pure water and a commercial agricultural solution on TiO2 coated media. Chemosphere 20080101
Mouse liver effects of cyproconazole, a triazole fungicide: role of the constitutive androstane receptor. Toxicological sciences : an official journal of the Society of Toxicology 20070901
Capabilities of different liquid chromatography tandem mass spectrometry systems in determining pesticide residues in food. Application to estimate their daily intake. Journal of chromatography. A 20070720
Sexual reproduction facilitates the adaptation of parasites to antagonistic host environments: Evidence from empirical study in the wheat-Mycosphaerella graminicola system. International journal for parasitology 20070701
MgMfs1, a major facilitator superfamily transporter from the fungal wheat pathogen Mycosphaerella graminicola, is a strong protectant against natural toxic compounds and fungicides. Fungal genetics and biology : FG & B 20070501
Testing estrogenicity of known and novel (xeno-)estrogens in the MolDarT using developing zebrafish (Danio rerio). Environmental toxicology 20070401
Use of SPE-GC/EIMS for residue analysis in wine elaborated from musts spiked with formulations of chlorpyriphos-methyl, methiocarb, dicofol, and cyproconazol. Journal of separation science 20070301
[Behaviour azole fungicide and fluconazole in Cryptococcus neoformans clinical and environmental isolates]. Revista da Sociedade Brasileira de Medicina Tropical 20070101
The toxicity study of a systemic fungicide: artea 330 EC on the physiology and the respiratory metabolism of the tadpole (Rana saharica). Communications in agricultural and applied biological sciences 20070101
Bioaccumulation and biotransformation of chiral triazole fungicides in rainbow trout (Oncorhynchus mykiss). Aquatic toxicology (Amsterdam, Netherlands) 20061230
Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. Toxicology 20061110
Fungicides affect the production of extracellular mucilaginous material (ECMM) and the peripheral growth unit (PGU) in two wood-rotting basidiomycetes. Mycological research 20061001
Influence of pH on the stereoselective degradation of the fungicides epoxiconazole and cyproconazole in soils. Environmental science & technology 20060901
Postulated pathogenic pathway in triazole fungicide induced dysmorphogenic effects. Reproductive toxicology (Elmsford, N.Y.) 20060801
Selection for increased cyproconazole tolerance in Mycosphaerella graminicola through local adaptation and in response to host resistance. Molecular plant pathology 20060701
MgSlt2, a cellular integrity MAP kinase gene of the fungal wheat pathogen Mycosphaerella graminicola, is dispensable for penetration but essential for invasive growth. Molecular plant-microbe interactions : MPMI 20060401
In vitro selection of an effective fungicide against Armillaria mellea and control of white root rot of grapevine in the field. Pest management science 20060301
Effects of two systemic fungicides: Artea (Propiconazole+cyproconazole) and Punch (Flusilazole) on the physiology and the respiratory metabolism of durum wheat (Triticum durum L.). Communications in agricultural and applied biological sciences 20060101
Determination of azolic fungicides in wine by solid-phase extraction and high-performance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry. Journal of chromatography. A 20050527
Capillary electrophoresis for analyzing pesticides in fruits and vegetables using solid-phase extraction and stir-bar sorptive extraction. Journal of chromatography. A 20050506
Application of solid-phase extraction to quantitatively determine cyproconazole and tebuconazole in treated wood using liquid chromatography with UV detection. Journal of chromatography. A 20050121
Determination of 22 triazole compounds including parent fungicides and metabolites in apples, peaches, flour, and water by liquid chromatography/tandem mass spectrometry. Journal of AOAC International 20050101
Liquid chromatography-electrospray quadrupole ion-trap mass spectrometry of nine pesticides in fruits. Journal of chromatography. A 20040903
Chiral separation of some triazole pesticides by supercritical fluid chromatography. Journal of chromatography. A 20040813
Evaluation of a method based on liquid chromatography/electrospray tandem mass spectrometry for analyzing eight triazolic and pyrimidine fungicides in extracts of processed fruits and vegetables. Journal of AOAC International 20040101
Multiple mechanisms account for variation in base-line sensitivity to azole fungicides in field isolates of Mycosphaerella graminicola. Pest management science 20031201
Triazole fungicide degradation in peaches in the field and in model systems. Food additives and contaminants 20030401
Molecular cloning and characterisation of three new ATP-binding cassette transporter genes from the wheat pathogen Mycosphaerella graminicola. Gene 20020501
High-performance chiral separation of fourteen triazole fungicides by sulfated beta-cyclodextrin-mediated capillary electrophoresis. Journal of chromatography. A 20010330
Properties