Home Other Building Blocks Thiazolidine

Thiazolidine

CAS No.:
504-78-9
Catalog Number:
AG0035OQ
Molecular Formula:
C3H7NS
Molecular Weight:
89.1594
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$50
- +
5g
95%
In Stock USA
United States
$101
- +
25g
95%
In Stock USA
United States
$283
- +
Product Description
Catalog Number:
AG0035OQ
Chemical Name:
Thiazolidine
CAS Number:
504-78-9
Molecular Formula:
C3H7NS
Molecular Weight:
89.1594
MDL Number:
MFCD00005211
IUPAC Name:
1,3-thiazolidine
InChI:
InChI=1S/C3H7NS/c1-2-5-3-4-1/h4H,1-3H2
InChI Key:
OGYGFUAIIOPWQD-UHFFFAOYSA-N
SMILES:
C1NCCS1
EC Number:
208-002-5
UNII:
I320806BKW
NSC Number:
357911
Properties
Complexity:
30.1  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
89.03g/mol
Formal Charge:
0
Heavy Atom Count:
5  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
89.156g/mol
Monoisotopic Mass:
89.03g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
37.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.3  
Literature
Title Journal
A novel thiazolidine compound induces caspase-9 dependent apoptosis in cancer cells. Bioorganic & medicinal chemistry 20120901
MMPT as a reactive oxygen species generator induces apoptosis via the depletion of intracellular GSH contents in A549 cells. European journal of pharmacology 20120805
Effectiveness of basal-supported oral therapy (BOT) using insulin glargine in patients with poorly controlled type 2 diabetes. The Tokai journal of experimental and clinical medicine 20120720
Intermolecular C-H···O and C-H···X interactions in substituted spiroacenaphthylene structures. Acta crystallographica. Section C, Crystal structure communications 20120701
Native chemical ligation of thioamide-containing peptides: development and application to the synthesis of labeled α-synuclein for misfolding studies. Journal of the American Chemical Society 20120606
Synthesis and cytotoxic activity of new acridine-thiazolidine derivatives. Bioorganic & medicinal chemistry 20120601
4-Benzyl-8-phenyl-1-thia-4-aza-spiro-[4.5]decan-3-one. Acta crystallographica. Section E, Structure reports online 20120501
2-[6-(4-Bromo-phen-yl)imidazo[2,1-b][1,3]thia-zol-3-yl]-N-[8-(4-hy-droxy-phen-yl)-2-methyl-3-oxo-1-thia-4-aza-spiro-[4.5]decan-4-yl]acetamide ethanol disolvate. Acta crystallographica. Section E, Structure reports online 20120501
Transformation of Pro-Leu-Gly-NH2 peptidomimetic positive allosteric modulators of the dopamine D2 receptor into negative modulators. ACS chemical neuroscience 20120418
Chiral Ni(II) coordination polymers: structure-driven effects of temperature and polyvinylpyrrolidone. Inorganic chemistry 20120416
Site-specific traceless coupling of potent cytotoxic drugs to recombinant antibodies for pharmacodelivery. Journal of the American Chemical Society 20120404
Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics. Amino acids 20120401
Modulation of liver L-γ-glutamyl-L-cysteinylglycine homeostasis by N-acetyl-glucosamine-thiazolidine-4(R)-carboxylic acid in mice. The American journal of the medical sciences 20120401
7'-Phenyl-1',3',5',6',7',7a'-hexa-hydro-dipiro[acenaphthyl-ene-1,5'-pyrrolo-[1,2-c]thia-zole-6',2''-indane]-2,1''(1H)-dione. Acta crystallographica. Section E, Structure reports online 20120401
IgE Sensitization to Cephalosporins in Health Care Workers. Allergy, asthma & immunology research 20120301
7'-(2,5-Dimeth-oxy-phen-yl)-1',3',5',6',7',7a'-hexa-hydro-dispiro-[indan-2,5'-pyrrolo-[1,2-c][1,3]thia-zole-6',2''-indan]-1,3,1''-trione. Acta crystallographica. Section E, Structure reports online 20120301
Methyl (2E)-2-[(2,4-dioxo-1,3-thia-zolidin-3-yl)meth-yl]-3-phenyl-prop-2-enoate. Acta crystallographica. Section E, Structure reports online 20120201
Recent progress in fluorescent and colorimetric chemosensors for detection of amino acids. Chemical Society reviews 20120107
Comprehensive evidence-based assessment and prioritization of potential antidiabetic medicinal plants: a case study from canadian eastern james bay cree traditional medicine. Evidence-based complementary and alternative medicine : eCAM 20120101
Methyl (Z)-2-[(2,4-dioxothia-zolidin-3-yl)meth-yl]-3-(2-methyl-phen-yl)prop-2-enoate. Acta crystallographica. Section E, Structure reports online 20120101
Effects of bezafibrate on lipid and glucose metabolism in dyslipidemic patients with diabetes: the J-BENEFIT study. Cardiovascular diabetology 20120101
Real-Time Analysis of Specific Protein-DNA Interactions with Surface Plasmon Resonance. Journal of amino acids 20120101
Branched intermediate formation is the slowest step in the protein splicing reaction of the Ala1 KlbA intein from Methanococcus jannaschii. Biochemistry 20111213
(Z)-N-{3-[(2-Chloro-1,3-thia-zol-5-yl)meth-yl]-1,3-thia-zolidin-2-yl-idene}cyanamide. Acta crystallographica. Section E, Structure reports online 20111201
14-Hy-droxy-11-[(E)-4-meth-oxy-benzyl-idene]-8-(4-meth-oxy-phen-yl)-5-thia-3,13-diaza-hepta-cyclo-[13.7.1.1.0.0.0.0]tetra-cosa-1(22),15(23),16,18,20-pentaen-10-one. Acta crystallographica. Section E, Structure reports online 20111101
(5E)-5-(2,4-Dichloro-benzyl-idene)-2-(piperidin-1-yl)-1,3-thia-zol-4(5H)-one. Acta crystallographica. Section E, Structure reports online 20111101
3-(2H-1,3-Benzodioxol-5-ylmeth-yl)-2-(2-meth-oxy-phen-yl)-1,3-thia-zolidin-4-one. Acta crystallographica. Section E, Structure reports online 20111101
Tandem thiol switch synthesis of peptide thioesters via N-S acyl shift on thiazolidine. Organic letters 20111007
The significance of peroxisomes in secondary metabolite biosynthesis in filamentous fungi. Biotechnology letters 20111001
3-Benzyl-2-phenyl-1,3-thia-zolidin-4-one. Acta crystallographica. Section E, Structure reports online 20111001
3-Benzyl-2-(furan-2-yl)-1,3-thia-zolidin-4-one. Acta crystallographica. Section E, Structure reports online 20111001
Studies on the electrochemical behavior of thiazolidine and its applications using a flow-through chronoamperometric sensor based on a gold electrode. Molecules (Basel, Switzerland) 20110906
Unveiling the roles of the glutathione redox system in vivo by analyzing genetically modified mice. Journal of clinical biochemistry and nutrition 20110901
Synthesis and anticancer activity of isatin-based pyrazolines and thiazolidines conjugates. Archiv der Pharmazie 20110801
4-Methyl-N-[(Z)-3-(4-methyl-phen-ylsulfon-yl)-1,3-thia-zolidin-2-yl-idene]benzene-sulfonamide. Acta crystallographica. Section E, Structure reports online 20110801
Traceless and site-specific ubiquitination of recombinant proteins. Journal of the American Chemical Society 20110720
Determination of a dipeptidyl peptidase IV agonist, β-aminoacyl containing thiazolidine derivatives (KR-66223) in rat plasma by liquid chromatography-tandem mass spectrometry. Journal of pharmaceutical and biomedical analysis 20110715
(±)-2-{3-[1-(2,4-Difluoro-phen-yl)eth-yl]-1,3-thia-zolidin-2-yl-idene}malononitrile. Acta crystallographica. Section E, Structure reports online 20110701
Quantum mechanical origin of the conformational preferences of 4-thiaproline and its S-oxides. Amino acids 20110601
Synthesis and characterization of dendron cross-linked PEG hydrogels as corneal adhesives. Biomacromolecules 20110509
rac-tert-Butyl 2-{5-[(4-{2-[methyl(pyri-din-2-yl)amino]ethoxy}phenyl)methyl]-2,4-dioxo-1,3-thiazolidin-3-yl}acetate. Acta crystallographica. Section E, Structure reports online 20110501
(Z)-N-{3-[(6-Chloro-pyridin-3-yl)meth-yl]-1,3-thia-zolidin-2-yl-idene}cyanamide. Acta crystallographica. Section E, Structure reports online 20110501
Design, synthesis and biological activity of thiazolidine-4-carboxylic acid derivatives as novel influenza neuraminidase inhibitors. Bioorganic & medicinal chemistry 20110401
N-[2-(4-Chloro-phen-yl)-5-methyl-4-oxo-1,3-thia-zolidin-3-yl]pyridine-3-carboxamide. Acta crystallographica. Section E, Structure reports online 20110401
N-[2-(4-Bromo-phen-yl)-5-methyl-4-oxo-1,3-thia-zolidin-3-yl]pyridine-3-carboxamide. Acta crystallographica. Section E, Structure reports online 20110401
Discovery of β-aminoacyl containing thiazolidine derivatives as potent and selective dipeptidyl peptidase IV inhibitors. Bioorganic & medicinal chemistry letters 20110301
Synthesis, characterization, antioxidant and antitumor evaluation of some new thiazolidine and thiazolidinone derivatives. Archiv der Pharmazie 20110301
Selective recognition of homocysteine and cysteine based on new ruthenium(II) complexes. Journal of inorganic biochemistry 20110301
[Detection of glimepiride and rosiglitazone from Chinese dietary supplements]. Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology 20110301
A convenient synthesis of novel thiazolidin-4-one-linked pseudodisaccharides by tandem Staudinger/aza-Wittig/cyclization and their biological evaluation. Carbohydrate research 20110215
N-[5-Methyl-2-(2-nitro-phen-yl)-4-oxo-1,3-thia-zolidin-3-yl]pyridine-3-carboxamide monohydrate. Acta crystallographica. Section E, Structure reports online 20110201
Crystal structures of (2R,4R)-2-(polyhydroxyalkyl)-1,3-thiazolidine-4-carboxylic acids: condensation products of l-cysteine with d-hexoses. Carbohydrate research 20110103
Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group. Bioorganic & medicinal chemistry letters 20110101
3-Benzyl-2-sulfanyl-idene-1,3-thia-zolidin-4-one. Acta crystallographica. Section E, Structure reports online 20110101
Integrin targeted delivery of gene therapeutics. Theranostics 20110101
The location of olfactory receptors within olfactory epithelium is independent of odorant volatility and solubility. BMC research notes 20110101
Occupational asthma in antibiotic manufacturing workers: case reports and systematic review. Journal of allergy 20110101
Antidiabetic pharmacotherapy and anamnestic hypoglycemia in a large cohort of type 2 diabetic patients--an analysis of the DiaRegis registry. Cardiovascular diabetology 20110101
[Thiazolidine derivatives]. Nihon rinsho. Japanese journal of clinical medicine 20110101
Penicillamine neurotoxicity: an hypothesis. ISRN neurology 20110101
Reversible inactivation of bovine plasma amine oxidase by cysteamine and related analogs. Biochemical and biophysical research communications 20101217
(Z)-N-[3-(4-Bromo-benzo-yl)-1,3-thia-zolidin-2-yl-idene]cyanamide. Acta crystallographica. Section E, Structure reports online 20101201
N-(3-Octyl-4-oxo-1,3-thia-zolidin-2-yl-idene)benzamide. Acta crystallographica. Section E, Structure reports online 20101201
Specificity of Staphyloferrin B recognition by the SirA receptor from Staphylococcus aureus. The Journal of biological chemistry 20101105
(Z)-N-[3-(Phenyl-sulfon-yl)thia-zolidin-2-yl-idene]cyanamide. Acta crystallographica. Section E, Structure reports online 20101101
(2R,4R)-3-(tert-But-oxy-carbon-yl)-2-(3-chloro-phen-yl)-1,3-thia-zolidine-4-carb-oxy-lic acid monohydrate. Acta crystallographica. Section E, Structure reports online 20101101
Suppression of NF-kappaB and GSK-3beta is involved in colon cancer cell growth inhibition by the PPAR agonist troglitazone. Chemico-biological interactions 20101006
{3-[(2-Chloro-1,3-thia-zol-4-yl)meth-yl]-1,3-thia-zolidin-2-yl-idene-amino}-formonitrile. Acta crystallographica. Section E, Structure reports online 20101001
Turn-on luminescent probe for cysteine/homocysteine based on a ruthenium(II) complex. Inorganic chemistry 20100906
Phosphorescence imaging of homocysteine and cysteine in living cells based on a cationic iridium(III) complex. Inorganic chemistry 20100719
Reduced synthesis of the Ybt siderophore or production of aberrant Ybt-like molecules activates transcription of yersiniabactin genes in Yersinia pestis. Microbiology (Reading, England) 20100701
1-(4-Fluoro-phen-yl)thio-urea. Acta crystallographica. Section E, Structure reports online 20100701
N-[(2S)-2-(4-Bromo-phen-yl)-4-oxo-1,3-thia-zolidin-3-yl]pyridine-3-carboxamide. Acta crystallographica. Section E, Structure reports online 20100701
N-(3-Butyl-4-oxo-1,3-thia-zolidin-2-yl-idene)benzamide. Acta crystallographica. Section E, Structure reports online 20100701
MMPT: a thiazolidin compound inhibits the growth of lung cancer H1792 cells via Fas-mediated and caspase-dependent apoptosis pathway. Investigational new drugs 20100601
Natural product-inspired synthesis of thiazolidine and thiazolidinone compounds and their anticancer activities. Current pharmaceutical design 20100601
Flexible ligand recognition of peroxisome proliferator-activated receptor-gamma (PPARgamma). Bioorganic & medicinal chemistry letters 20100601
Synthesis of novel MMT/acyl-protected nucleo alanine monomers for the preparation of DNA/alanyl-PNA chimeras. Amino acids 20100501
1-(2-Fluoro-phen-yl)-3-(3,4,5-trimethoxy-benzo-yl)thio-urea. Acta crystallographica. Section E, Structure reports online 20100501
(Z)-N-(3-Nicotinoyl-1,3-thia-zolidin-2-yl-idene)cyanamide. Acta crystallographica. Section E, Structure reports online 20100501
[Thiazolidine]. Nihon rinsho. Japanese journal of clinical medicine 20100401
1,3-Dithian-2-one azine. Acta crystallographica. Section E, Structure reports online 20100401
4-(9,10-Dihydroacridin-9-ylidene)thiosemicarbazide and its five-membered thiazole and six-membered thiazine derivatives. Acta crystallographica. Section C, Crystal structure communications 20100201
Synthesis, in vitro structure-activity relationship, and in vivo studies of 2-arylthiazolidine-4-carboxylic acid amides as anticancer agents. Bioorganic & medicinal chemistry 20100115
Anti-hyperglycemic and anti-hyperlipidemic effects of guava leaf extract. Nutrition & metabolism 20100101
Vaticanol C, a resveratrol tetramer, activates PPARalpha and PPARbeta/delta in vitro and in vivo. Nutrition & metabolism 20100101
Troglitazone suppresses telomerase activity independently of PPARgamma in estrogen-receptor negative breast cancer cells. BMC cancer 20100101
Efficient Electrochemical Synthesis, Antimicrobial and Antiinflammatory Activity of 2-amino-5-substituted- 1,3,4-oxadiazole Derivatives. Indian journal of pharmaceutical sciences 20100101
Kinetic analysis of cysteine desulfurase CD0387 from Synechocystis sp. PCC 6803: formation of the persulfide intermediate. Biochemistry 20091222
Integration of heterogeneous expression data sets extends the role of the retinol pathway in diabetes and insulin resistance. Bioinformatics (Oxford, England) 20091201
Cysteine-reactive covalent capture tags for enrichment of cysteine-containing peptides. Rapid communications in mass spectrometry : RCM 20091101
Reflections on protein splicing: structures, functions and mechanisms. Proceedings of the Japan Academy. Series B, Physical and biological sciences 20091101
4-(1,3-Thia-zolidin-2-yl)phenol. Acta crystallographica. Section E, Structure reports online 20091101
Structural basis of the inhibition of class A beta-lactamases and penicillin-binding proteins by 6-beta-iodopenicillanate. Journal of the American Chemical Society 20091028
N-(2,4-Dioxo-1,3-thia-zolidin-3-yl)-2-(4-isobutyl-phen-yl)propanamide. Acta crystallographica. Section E, Structure reports online 20090901
Reversible thiazolidine exchange: a new reaction suitable for dynamic combinatorial chemistry. Organic letters 20090806
Screening for glucose-triggered modifications of glutathione. Journal of peptide science : an official publication of the European Peptide Society 20090801
Covalent binding of penicillamine to macrophages: implications for penicillamine-induced autoimmunity. Chemical research in toxicology 20090701
(Z)-{[3-(Hydroxy-meth-yl)-1,3-thia-zolidin-2-yl-idene]amino}formonitrile. Acta crystallographica. Section E, Structure reports online 20090701
Puckering transitions of pseudoproline residues. Biopolymers 20090601
Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. European journal of medicinal chemistry 20090501
Concise synthesis of tricyclic isoindolinones via one-pot cascade multicomponent sequences. Organic letters 20090416
Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1. Blood 20090226
(3RS)-S-[1-(3-Chloro-phen-yl)-2-oxopyr-roli-din-3-yl]thio-uronium bromide. Acta crystallographica. Section E, Structure reports online 20090201
The effects of Thiazolidinediones on metabolic complications and Lipodystrophy in HIV-infected patients. PPAR research 20090101
Chemical probes that competitively and selectively inhibit Stat3 activation. PloS one 20090101
Identification of hematein as a novel inhibitor of protein kinase CK2 from a natural product library. BMC cancer 20090101
Expression of the peroxisome proliferator activated receptor gamma gene is repressed by DNA methylation in visceral adipose tissue of mouse models of diabetes. BMC biology 20090101
N-[(Z)-3-(4-Chloro-benzo-yl)-1,3-thia-zolidin-2-yl-idene]cyanamide. Acta crystallographica. Section E, Structure reports online 20081201
Comparative metabolism and pharmacokinetics of seven neonicotinoid insecticides in spinach. Journal of agricultural and food chemistry 20081112
(E)-Ethyl 2-cyano-2-(thia-zolidin-2-yl-idene)acetate. Acta crystallographica. Section E, Structure reports online 20081101
NMR and theoretical calculations: a unified view of the cis/trans isomerization of 2-substituted thiazolidines containing peptides. The journal of physical chemistry. B 20080814
8-Methyl-4-morpholinoethyl-1-thia-4-aza-spiro-[4.5]decan-3-one. Acta crystallographica. Section E, Structure reports online 20080801
Acarbose treatment increases serum total adiponectin levels in patients with type 2 diabetes. Endocrine journal 20080701
Ethyl 2-[(Z)-2-cyano-imino-1,3-thiazolidin-3-yl]acetate. Acta crystallographica. Section E, Structure reports online 20080701
Design, synthesis and evaluation of potent thymidylate synthase X inhibitors. Bioorganic & medicinal chemistry letters 20080615
Synthesis and antiproliferative activity of imidazole and imidazoline analogs for melanoma. Bioorganic & medicinal chemistry letters 20080601
Neurodegenerative diseases of the retina and potential for protection and recovery. Current neuropharmacology 20080601
Fluorophore-labeled beta-lactamase as a biosensor for beta-lactam antibiotics: a study of the biosensing process. Journal of the American Chemical Society 20080521
Controlling orientations of immobilized oligopeptides using N-terminal cysteine labels. Langmuir : the ACS journal of surfaces and colloids 20080520
Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents. European journal of medicinal chemistry 20080301
Semisynthetic analogues of PSC-RANTES, a potent anti-HIV protein. Bioconjugate chemistry 20080201
1'-Phenyl-6'-thia-cyclo-heptane-1-spiro-2'-perhydro-pyrrolizine-3'-spiro-3''-indoline-2,2''-dione. Acta crystallographica. Section E, Structure reports online 20080201
3-(4-Methoxy-phen-yl)-6-(phenyl-sulfon-yl)perhydro-1,3-thiazolo[3',4':1,2]pyrrolo[4,5-c]pyrrole. Acta crystallographica. Section E, Structure reports online 20080201
Identification of cellular pathways affected by Sortin2, a synthetic compound that affects protein targeting to the vacuole in Saccharomyces cerevisiae. BMC chemical biology 20080101
Impact of the socioeconomic status on the probability of receiving formulary restricted thiazolidine (TZDs). The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20080101
Role of Peoxisome Proliferator Activator Receptor gamma on Blood Retinal Barrier Breakdown. PPAR research 20080101
Are the adverse effects of glitazones linked to induced testosterone deficiency? Cardiovascular diabetology 20080101
Synthesis, Antimicrobial and Antiinflammatory Activity of 2,5-Disubstituted-1,3,4-oxadiazoles. Indian journal of pharmaceutical sciences 20080101
(S)-1-[(S)-4-Benzyl-2-thioxothia-zolidin-3-yl]-3-hydroxy-butan-1-one. Acta crystallographica. Section E, Structure reports online 20080101
Synthesis and Pharmacological Evaluation of Azetidin-2-ones and Thiazolidin-4-ones Encompassing Benzothiazole. Indian journal of pharmaceutical sciences 20080101
Conformational preferences of pseudoproline residues. The journal of physical chemistry. B 20071101
3D-QSAR studies of Dipeptidyl peptidase IV inhibitors using a docking based alignment. Journal of molecular modeling 20071001
Lipids behavior and adverse effects for oral antidiabetic agents in patients with Type 2 diabetes treated with sulfonylureas alone based on systematic review. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071001
Synthesis and antiproliferative activity of thiazolidine analogs for melanoma. Bioorganic & medicinal chemistry letters 20070801
Synthesis and anti-HIV studies of 2-adamantyl-substituted thiazolidin-4-ones. European journal of medicinal chemistry 20070701
Insecticidal and neuroblocking potencies of variants of the imidazolidine moiety of imidacloprid-related neonicotinoids and the relationship to partition coefficient and charge density on the pharmacophore. Journal of agricultural and food chemistry 20070207
Conformational stability of Abeta-(25-35) in the presence of thiazolidine derivatives. Chemical biology & drug design 20070201
Cardiovascular benefits and safety profile of acarbose therapy in prediabetes and established type 2 diabetes. Cardiovascular diabetology 20070101
Reversal of systemic hypertension-associated cardiac remodeling in chronic pressure overload myocardium by ciglitazone. International journal of biological sciences 20070101
Design, synthesis and antibacterial activity of novel 1,3-thiazolidine pyrimidine nucleoside analogues. Bioorganic & medicinal chemistry 20061115
Direct trapping of formaldehyde formed via oxidative N-demethylation of N,N-dialkylarylamines by Bacillus megaterium using cysteamine derivatization. Journal of microbiological methods 20061101
Determination of glyoxylyl-peptide concentration using oxime chemistry and RP-HPLC analysis. Journal of peptide science : an official publication of the European Peptide Society 20061101
Ring opening and expansion of aziridines in a silica-water reaction medium. The Journal of organic chemistry 20060915
Purification and characterization of a novel L-2-amino-Delta2-thiazoline-4-carboxylic acid hydrolase from Pseudomonas sp. strain ON-4a expressed in E. coli. Applied microbiology and biotechnology 20060901
[Analysis of variant and modified structures of proteins by mass spectrometry--application for clinical laboratory test]. Rinsho byori. The Japanese journal of clinical pathology 20060901
Enhanced bioavailability of a new thiazolidine derivative FPFS-410, an antidiabetic and lipid-lowering drug, after oral administration of its hydroxypropyl-beta-cyclodextrin complex to bile duct-cannulated rats. Journal of pharmaceutical sciences 20060801
[(S)-gamma-(Arylamino)prolyl]thiazolidine compounds as a novel series of potent and stable DPP-IV inhibitors. Bioorganic & medicinal chemistry 20060601
Conformational behavior of dimethyl 5-methyl-1H,3H-pyrrolo[1,2-c][1,3]thiazole-6,7-dicarboxylate 2,2-dioxide isolated in low-temperature matrixes. The journal of physical chemistry. A 20060525
Stabilization of the biologically active conformation of the principal neutralizing determinant of HIV-1(IIIB) containing a cis-proline surrogate: 1H NMR and molecular modeling study. Biochemistry 20060404
Antitumor activity and downregulation of pro-angiogenic molecules in human prostate cancer cells by a novel thiazolidione compound. The Prostate 20060301
Improvement of solubility and oral bioavailability of 2-(N-cyanoimino)-5-[(E)-4-styrylbenzylidene]-4-oxothiazolidine (FPFS-410) with antidiabetic and lipid-lowering activities in dogs by 2-hydroxypropyl-beta-cyclodextrin. Chemical & pharmaceutical bulletin 20060301
A study of anti-inflammatory activity of some novel alpha-amino naphthalene and beta-amino naphthalene derivatives. Archiv der Pharmazie 20060301
Development of a compound-specific carbon isotope analysis method for atmospheric formaldehyde via NaHSO3 and cysteamine derivatization. Analytical chemistry 20060215
An automated peptide and protein thiazolidine coupling chemistry for biosensor immobilization giving a unique N-terminal orientation. Analytical biochemistry 20060115
Alpha-thiolamines such as cysteine and cysteamine act as effective transglycating agents due to formation of irreversible thiazolidine derivatives. Medical hypotheses 20060101
Spectrophotometric Analysis of the Cyanide Metabolite 2-Aminothiazoline-4-Carboxylic Acid (ATCA). Toxicology mechanisms and methods 20060101
Chemical synthesis of proteins and circular peptides using Nalpha-(1-phenyl-2-mercaptoethyl) auxiliaries. Protein and peptide letters 20051101
JNK1-dependent antimitotic activity of thiazolidin compounds in human non-small-cell lung and colon cancer cells. Cellular and molecular life sciences : CMLS 20051001
Protein splicing: its discovery and structural insight into novel chemical mechanisms. IUBMB life 20050801
Identification of a novel synthetic thiazolidin compound capable of inducing c-Jun NH2-terminal kinase-dependent apoptosis in human colon cancer cells. Cancer research 20050715
Synthesis and evaluation of 3-(carboxymethylidene)- and 3-(carboxymethyl)penicillinates as inhibitors of beta-lactamase. The Journal of organic chemistry 20050527
2-(Acridin-9-ylimino)-3-dimethylamino-1,3-thiazolidin-4-one. Acta crystallographica. Section C, Crystal structure communications 20050401
Mechanisms of antibiotic resistance: QM/MM modeling of the acylation reaction of a class A beta-lactamase with benzylpenicillin. Journal of the American Chemical Society 20050330
Regulation of serine racemase activity by amino acids. Brain research. Molecular brain research 20050218
Chemical methods for peptide-oligonucleotide conjugate synthesis. Methods in molecular biology (Clifton, N.J.) 20050101
Parallel synthesis and biological evaluation of different sizes of bicyclo[2,3]-Leu-enkephalin analogues. Biopolymers 20050101
Identification and characterisation of a new class of highly specific and potent inhibitors of the mitochondrial pyruvate carrier. Biochimica et biophysica acta 20050101
Use of carbonyl group addition--elimination reactions for synthesis of nucleic acid conjugates. Bioconjugate chemistry 20050101
Synthesis of N alpha-(1-phenyl-2-mercaptoethyl) amino acids, new building blocks for ligation and cyclization at non-cysteine sites: scope and limitations in peptide synthesis. The Journal of organic chemistry 20041224
Antidiabetic and adipogenic properties in a newly synthesized thiazolidine derivative, FPFS-410. Metabolism: clinical and experimental 20041201
Novel rhodium-catalyzed reaction of thiazolidine derivatives with carbodiimides. Chemistry (Weinheim an der Bergstrasse, Germany) 20041119
Strecker-type degradation produced by the lipid oxidation products 4,5-epoxy-2-alkenals. Journal of agricultural and food chemistry 20041117
Dendritic macromers as in situ polymerizing biomaterials for securing cataract incisions. Journal of the American Chemical Society 20041013
N-Salicylideneamino acidato complexes of oxovanadium(IV). The cysteine and penicillamine complexes. Dalton transactions (Cambridge, England : 2003) 20040921
Barriers to internal rotation around the C-N bond in 3-(o-aryl)-5-methyl-rhodanines using NMR spectroscopy and computational studies. Electron density topological analysis of the transition states. Organic & biomolecular chemistry 20040907
Analgesic activity of new synthetic thiazolidine-4-ones derivatives. Indian journal of experimental biology 20040801
Formaldehyde scavenging from peritoneal dialysis solutions using reduced aminothiol compounds. Nephrology (Carlton, Vic.) 20040401
Ninhydrin as a reversible protecting group of amino-terminal cysteine. The journal of peptide research : official journal of the American Peptide Society 20040301
Saponins from the bark of Nephelium maingayi. Journal of natural products 20040201
Synthesis of antitumor 6-alkylidenepenicillanate sulfones and related 3-alkylidene-2-azetidinones. Bioorganic & medicinal chemistry letters 20040105
Protein splicing of yeast VMA1-derived endonuclease via thiazolidine intermediates. Journal of synchrotron radiation 20040101
Efficient conjugation and characterization of distamycin-based peptides with selected oligonucleotide stretches. Bioconjugate chemistry 20040101
Chemoselective oxime and thiazolidine bond formation: a versatile and efficient route to the preparation of 3'-peptide-oligonucleotide conjugates. Nucleosides, nucleotides & nucleic acids 20040101
Antiedematogenic activity of two thiazolidine derivatives: N-tryptophyl-5-(3,5-di-tert-butyl-4-hydroxybenzylidene) rhodanine (GS26) and N-tryptophyl-5-(3,5-di-tert-butyl-4-hydroxybenzylidene)-2,4-thiazolidinedione (GS28). Chemical & pharmaceutical bulletin 20031201
Conformational properties of penicillins: quantum chemical calculations and molecular dynamics simulations of benzylpenicillin. Journal of computational chemistry 20031130
Binding of acetaldehyde to a glutathione metabolite: mass spectrometric characterization of an acetaldehyde-cysteinylglycine conjugate. Alcoholism, clinical and experimental research 20031001
The neonicotinoid electronegative pharmacophore plays the crucial role in the high affinity and selectivity for the Drosophila nicotinic receptor: an anomaly for the nicotinoid cation--pi interaction model. Biochemistry 20030701
Physicochemical and crystal structure analyses of the antidiabetic agent troglitazone. Chemical & pharmaceutical bulletin 20030701
1,3-thiazolidine derivatives from regioselective [2+3]-cycloadditions of azomethine ylides with thioketones. Acta crystallographica. Section C, Crystal structure communications 20030501
Designing supramolecular structures from models of cyclic peptide scaffolds with heterocyclic constraints. Journal of molecular graphics & modelling 20030301
Reactions of 5-mercaptoazoles and pyridine-2-thiones with acetylenic esters. Selectivity of the formation of novel fused thiazin-4-ones and thiazolidin-4-ones. Organic & biomolecular chemistry 20030107
Gamma (gamma) tocopherol upregulates peroxisome proliferator activated receptor (PPAR) gamma (gamma) expression in SW 480 human colon cancer cell lines. BMC cancer 20030101
Highly efficient synthesis of peptide- and carbohydrate-oligonucleotide conjugates using chemoselective oxime and thiazolidine formation. Nucleosides, nucleotides & nucleic acids 20030101
Direct chiral separation of troglitazone stereoisomers using reversed-phase high-performance liquid chromatography. Journal of pharmaceutical and biomedical analysis 20021015
High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening. The Journal of biological chemistry 20021004
New oxorhenium(V) complexes from the widely used diaminedithiol (DADT) ligand system. Inorganic chemistry 20020909
Synthesis and antimicrobial activity of new substituted anilinobenzimidazoles. Archives of pharmacal research 20020601
Heterocyclic compounds as inflammation inhibitors. Current medicinal chemistry 20020501
New thiazane and thiazolidine PNA monomers: synthesis, incorporation into PNAs and hybridization studies. Bioorganic & medicinal chemistry letters 20020408
Synthesis and antibacterial activity of 1beta-methyl-2-(5-substituted thiazolidinopyrrolidin-3-ylthio)carbapenems and related compounds. Archiv der Pharmazie 20020401
Specific determination of cysteine and penicillamine through cyclization to 2-thioxothiazolidine-4-carboxylic acids. Talanta 20020311
Protein-splicing reaction via a thiazolidine intermediate: crystal structure of the VMA1-derived endonuclease bearing the N and C-terminal propeptides. Journal of molecular biology 20020301
Dehydrotrametenolic acid induces preadipocyte differentiation and sensitizes animal models of noninsulin-dependent diabetes mellitus to insulin. Biological & pharmaceutical bulletin 20020101
Immobilization of pectin fragments on solid supports: novel coupling by thiazolidine formation. Bioconjugate chemistry 20020101
Synthesis of peptide-oligonucleotide conjugates with single and multiple peptides attached to 2'-aldehydes through thiazolidine, oxime, and hydrazine linkages. Bioconjugate chemistry 20020101
Pioglitazone: cardiovascular effects in prediabetic patients. Cardiovascular drug reviews 20020101
Synthesis, isolation and characterization of Plasmodium falciparum antigenic tetrabranched peptide dendrimers obtained by thiazolidine linkages. The journal of peptide research : official journal of the American Peptide Society 20011001
Highly efficient synthesis of peptide-oligonucleotide conjugates: chemoselective oxime and thiazolidine formation. Chemistry (Weinheim an der Bergstrasse, Germany) 20010917
Assessment of structural features of the pseudomonas siderophore pyochelin required for its ability to promote oxidant-mediated endothelial cell injury. Archives of biochemistry and biophysics 20010915
In vitro reconstitution of the Pseudomonas aeruginosa nonribosomal peptide synthesis of pyochelin: characterization of backbone tailoring thiazoline reductase and N-methyltransferase activities. Biochemistry 20010731
Troglitazone quinone formation catalyzed by human and rat CYP3A: an atypical CYP oxidation reaction. Biochemical pharmacology 20010715
Tartric acid-based linker for the solid-phase synthesis of C-terminal peptide alpha-oxo aldehydes. The Journal of organic chemistry 20010615
Palladium-catalyzed cyclization reactions of 2-vinylthiiranes with heterocumulenes. Regioselective and enantioselective formation of thiazolidine, oxathiolane, and dithiolane derivatives. The Journal of organic chemistry 20010518
Enantioselective addition of a chiral thiazolidinethione-derived titanium enolate to acetals. Organic letters 20010222
Synthesis by chemoselective ligation and biological evaluation of novel cell-permeable PKC-zeta pseudosubstrate lipopeptides. Journal of medicinal chemistry 20010201
Peptide and small molecule microarray for high throughput cell adhesion and functional assays. Bioconjugate chemistry 20010101
Fine structural recognition specificities of IgE antibodies distinguishing amoxicilloyl and amoxicillanyl determinants in allergic subjects. Journal of molecular recognition : JMR 20010101
Chloride transport and its inhibition by thiocyanate in gills of seawater teleosts. Comparative biochemistry and physiology. A, Comparative physiology 19751201
Properties