Activation of the Nrf2-ARE pathway by the Alternaria alternata mycotoxins altertoxin I and II.

Archives of toxicology 20170101

Characterization of heme oxygenase and biliverdin reductase gene expression in zebrafish (Danio rerio): Basal expression and response to pro-oxidant exposures.

Toxicology and applied pharmacology 20161115

P450 3A-Catalyzed O-Dealkylation of Lapatinib Induces Mitochondrial Stress and Activates Nrf2.

Chemical research in toxicology 20160516

Antioxidant tert-butylhydroquinone ameliorates arsenic-induced intracellular damages and apoptosis through induction of Nrf2-dependent antioxidant responses as well as stabilization of anti-apoptotic factor Bcl-2 in human keratinocytes.

Free radical biology & medicine 20160501

10-Oxo-trans-11-octadecenoic acid generated from linoleic acid by a gut lactic acid bacterium Lactobacillus plantarum is cytoprotective against oxidative stress.

Toxicology and applied pharmacology 20160401

Erk-Creb pathway suppresses glutathione-S-transferase pi expression under basal and oxidative stress conditions in zebrafish embryos.

Toxicology letters 20160105

Nrf2-dependent repression of interleukin-12 expression in human dendritic cells exposed to inorganic arsenic.

Free radical biology & medicine 20151101

Protective roles of aldo-keto reductase 1B10 and autophagy against toxicity induced by p-quinone metabolites of tert-butylhydroquinone in lung cancer A549 cells.

Chemico-biological interactions 20150605

Population-based in vitro hazard and concentration-response assessment of chemicals: the 1000 genomes high-throughput screening study.

Environmental health perspectives 20150501

Solanesol protects human hepatic L02 cells from ethanol-induced oxidative injury via upregulation of HO-1 and Hsp70.

Toxicology in vitro : an international journal published in association with BIBRA 20150401

Protective effect of nuclear factor E2-related factor 2 on inflammatory cytokine response to brominated diphenyl ether-47 in the HTR-8/SVneo human first trimester extravillous trophoblast cell line.

Toxicology and applied pharmacology 20141115

Cooperation of structurally different aryl hydrocarbon receptor agonists and β-catenin in the regulation of CYP1A expression.

Toxicology 20141105

Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells.

British journal of cancer 20140826

Regulation of human CYP2C9 expression by electrophilic stress involves activator protein 1 activation and DNA looping.

Molecular pharmacology 20140801

Tert-butylhydroquinone as a phenolic activator of Nrf2 antagonizes arsenic-induced oxidative cytotoxicity but promotes arsenic methylation and detoxication in human hepatocyte cell line.

Biological trace element research 20140801

Nrf2 expression and activity in human T lymphocytes: stimulation by T cell receptor activation and priming by inorganic arsenic and tert-butylhydroquinone.

Free radical biology & medicine 20140601

Intronic DNA elements regulate Nrf2 chemical responsiveness of the human microsomal epoxide hydrolase gene (EPHX1) through a far upstream alternative promoter.

Biochimica et biophysica acta 20140601

Pau d'arco activates Nrf2-dependent gene expression via the MEK/ERK-pathway.

The Journal of toxicological sciences 20140401

Discovery of potent Keap1-Nrf2 protein-protein interaction inhibitor based on molecular binding determinants analysis.

Journal of medicinal chemistry 20140327

Inhibitory effects of tert-butylhydroquinone on osteoclast differentiation via up-regulation of heme oxygenase-1 and down-regulation of HMGB1 release and NFATc1 expression.

Journal of applied toxicology : JAT 20140101

Involvement of the Nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress.

Journal of pharmacological sciences 20140101

Isoniazid suppresses antioxidant response element activities and impairs adipogenesis in mouse and human preadipocytes.

Toxicology and applied pharmacology 20131215

Keap1 silencing boosts lipopolysaccharide-induced transcription of interleukin 6 via activation of nuclear factor κB in macrophages.

Toxicology and applied pharmacology 20131101

The Nrf2 activator, tBHQ, differentially affects early events following stimulation of Jurkat cells.

Toxicological sciences : an official journal of the Society of Toxicology 20131101

Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells.

Pharmacological research 20131001

Metformin inhibits heme oxygenase-1 expression in cancer cells through inactivation of Raf-ERK-Nrf2 signaling and AMPK-independent pathways.

Toxicology and applied pharmacology 20130901

Role of AMP-activated protein kinase in ferritin H gene expression by resveratrol in human T cells.

Biochemistry 20130730

Arsenic inhibits autophagic flux, activating the Nrf2-Keap1 pathway in a p62-dependent manner.

Molecular and cellular biology 20130601

Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease.

Antioxidants & redox signaling 20130110

Fast analysis of synthetic antioxidants in edible vegetable oil using trilinear component modeling of liquid chromatography-diode array detection data.

Journal of chromatography. A 20121116

Neuroprotective effects of tert-butylhydroquinone on paraquat-induced dopaminergic cell degeneration in C57BL/6 mice and in PC12 cells.

Archives of toxicology 20121101

Deficiency in the nuclear factor E2-related factor 2 renders pancreatic β-cells vulnerable to arsenic-induced cell damage.

Toxicology and applied pharmacology 20121101

Water quality assessment using the AREc32 reporter gene assay indicative of the oxidative stress response pathway.

Journal of environmental monitoring : JEM 20121101

The nuclear factor erythroid 2-like 2 activator, tert-butylhydroquinone, improves cognitive performance in mice after mild traumatic brain injury.

Neuroscience 20121025

Neuroprotective effects of phenolic antioxidant tBHQ associate with inhibition of FoxO3a nuclear translocation and activity.

Journal of neurochemistry 20121001

Fast simultaneous determination of BHA and TBHQ antioxidants in biodiesel by batch injection analysis using pulsed-amperometric detection.

Talanta 20120915

Paradoxical cytotoxicity of tert-butylhydroquinone in vitro: What kills the untreated cells?

Archives of toxicology 20120901

An effective strategy for increasing the radiosensitivity of Human lung Cancer cells by blocking Nrf2-dependent antioxidant responses.

Free radical biology & medicine 20120815

Regulatory role of KEAP1 and NRF2 in PPARγ expression and chemoresistance in human non-small-cell lung carcinoma cells.

Free radical biology & medicine 20120815

Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan.

American journal of physiology. Endocrinology and metabolism 20120815

Validation of the multiple sensor mechanism of the Keap1-Nrf2 system.

Free radical biology & medicine 20120815

Nrf2-ARE pathway regulates induction of Sestrin-2 expression.

Free radical biology & medicine 20120815

Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the nuclear factor erythroid 2-related factor 2 pathway.

The Journal of pharmacology and experimental therapeutics 20120701

Oxidative stability of virgin olive oil as affected by the bene unsaponifiable matters and tertiary-butylhydroquinone.

Journal of food science 20120601

Effects of oxidative stress caused by tert-butylhydroquinone on cytotoxicity in MDCK cells.

The Journal of veterinary medical science 20120501

Modulation of transcription factor Nrf2 in an in vitro model of traumatic brain injury.

Journal of neurotrauma 20120410

Cross-regulations among NRFs and KEAP1 and effects of their silencing on arsenic-induced antioxidant response and cytotoxicity in human keratinocytes.

Environmental health perspectives 20120401

Determination of lutein by high-performance thin-layer chromatography using densitometry and screening of major dietary carotenoids in food supplements.

Journal of chromatography. A 20120330

Nrf2 protein up-regulates antiapoptotic protein Bcl-2 and prevents cellular apoptosis.

The Journal of biological chemistry 20120323

4-Ketopinoresinol, a novel naturally occurring ARE activator, induces the Nrf2/HO-1 axis and protects against oxidative stress-induced cell injury via activation of PI3K/AKT signaling.

Free radical biology & medicine 20120315

In vitro bioassay for reactive toxicity towards proteins implemented for water quality monitoring.

Journal of environmental monitoring : JEM 20120301

Reduction of misleading ('false') positive results in mammalian cell genotoxicity assays. I. Choice of cell type.

Mutation research 20120218

Th2 skewing by activation of Nrf2 in CD4(+) T cells.

Journal of immunology (Baltimore, Md. : 1950) 20120215

Nrf2b, novel zebrafish paralog of oxidant-responsive transcription factor NF-E2-related factor 2 (NRF2).

The Journal of biological chemistry 20120210

A synthetic chalcone as a potent inducer of glutathione biosynthesis.

Journal of medicinal chemistry 20120209

Tert-Butylhydroquinone pretreatment protects kidney from ischemia-reperfusion injury.

Journal of nephrology 20120101

The ToxTracker assay: novel GFP reporter systems that provide mechanistic insight into the genotoxic properties of chemicals.

Toxicological sciences : an official journal of the Society of Toxicology 20120101

Quinolinic Acid, an endogenous molecule combining excitotoxicity, oxidative stress and other toxic mechanisms.

International journal of tryptophan research : IJTR 20120101

Reduction of cytotoxic p-quinone metabolites of tert-butylhydroquinone by human aldo-keto reductase (AKR) 1B10.

Drug metabolism and pharmacokinetics 20120101

Ethanol-mediated regulation of cytochrome P450 2A6 expression in monocytes: role of oxidative stress-mediated PKC/MEK/Nrf2 pathway.

PloS one 20120101

Prevention of diabetic complications by activation of Nrf2: diabetic cardiomyopathy and nephropathy.

Experimental diabetes research 20120101

Dietary polyphenols as modulators of brain functions: biological actions and molecular mechanisms underpinning their beneficial effects.

Oxidative medicine and cellular longevity 20120101

Visible-light-promoted degradation of the antioxidants propyl gallate and t-butylhydroquinone: mechanistic aspects.

Redox report : communications in free radical research 20120101

Implementation of a high-throughput screen for identifying small molecules to activate the Keap1-Nrf2-ARE pathway.

PloS one 20120101

Inhibitor of Nrf2 (INrf2 or Keap1) protein degrades Bcl-xL via phosphoglycerate mutase 5 and controls cellular apoptosis.

The Journal of biological chemistry 20111230

Polyphenols activate Nrf2 in astrocytes via H2O2, semiquinones, and quinones.

Free radical biology & medicine 20111215

Free-radical scavenging properties and reducing power of grape cane extracts from 11 selected grape cultivars widely grown in China.

Molecules (Basel, Switzerland) 20111206

A defect in Nrf2 signaling constitutes a mechanism for cellular stress hypersensitivity in a genetic rat model of type 2 diabetes.

American journal of physiology. Endocrinology and metabolism 20111201

Evaluation of polyphenol contents in differently processed apricots using accelerated solvent extraction followed by high-performance liquid chromatography-diode array detector.

International journal of food sciences and nutrition 20111101

Heme induces heme oxygenase 1 via Nrf2: role in the homeostatic macrophage response to intraplaque hemorrhage.

Arteriosclerosis, thrombosis, and vascular biology 20111101

Preventive effect of tert-butylhydroquinone on cisplatin-induced nephrotoxicity in rats.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20111001

Calcium fluxes into and out of cytosol in human platelets: analysis of experimental data.

Biochemical and biophysical research communications 20110909

Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease.

Disease models & mechanisms 20110901

Unveiling the roles of the glutathione redox system in vivo by analyzing genetically modified mice.

Journal of clinical biochemistry and nutrition 20110901

Participation of covalent modification of Keap1 in the activation of Nrf2 by tert-butylbenzoquinone, an electrophilic metabolite of butylated hydroxyanisole.

Toxicology and applied pharmacology 20110815

NF-E2-related factor 2 activation in PC12 cells: its protective role in manganese-induced damage.

Archives of toxicology 20110801

Acidic Ca(2+) stores in platelets.

Cell calcium 20110801

Stabilization of Nrf2 by tBHQ prevents LPS-induced apoptosis in differentiated PC12 cells.

Molecular and cellular biochemistry 20110801

Acidic NAADP-releasable Ca(2+) compartments in the megakaryoblastic cell line MEG01.

Biochimica et biophysica acta 20110801

tert-Butylhydroquinone as a spectroscopic probe for the superoxide radical scavenging activity assay of biological samples.

Analytical chemistry 20110715

Effect of antioxidants on soy oil conjugated linoleic acid production and its oxidative stability.

Journal of agricultural and food chemistry 20110713

Protective effect of tert-butylhydroquinone on cerebral inflammatory response following traumatic brain injury in mice.

Injury 20110701

Pressurized liquid extraction of phenolic compounds from Anatolia propolis and their radical scavenging capacities.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110701

[Terahertz spectroscopic testing of food additive tert-butylhydroquinone].

Guang pu xue yu guang pu fen xi = Guang pu 20110701

Fish oil and olive oil can modify insulin resistance and plasma desacyl-ghrelin in rats.

Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110701

The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics.

Chemico-biological interactions 20110630

Induction of human fetal hemoglobin via the NRF2 antioxidant response signaling pathway.

Blood 20110602

tBHQ-induced HO-1 expression is mediated by calcium through regulation of Nrf2 binding to enhancer and polymerase II to promoter region of HO-1.

Chemical research in toxicology 20110516

Nuclear factor p65 interacts with Keap1 to repress the Nrf2-ARE pathway.

Cellular signalling 20110501

Dietary supplementation with tBHQ, an Nrf2 stabilizer molecule, confers neuroprotection against apoptosis in amyloid β-injected rat.

Neurochemical research 20110501

The Nrf2-inducible antioxidant defense in astrocytes can be both up- and down-regulated by activated microglia:Involvement of p38 MAPK.

Glia 20110501

Discovery of novel SERCA inhibitors by virtual screening of a large compound library.

European journal of medicinal chemistry 20110501

[Antagonism of tert-butylhydroquinone on neurotoxicity and oxidative stress induced by paraquat in PC12].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20110401

INrf2 (Keap1) targets Bcl-2 degradation and controls cellular apoptosis.

Cell death and differentiation 20110301

Monitoring the intracellular store Ca2+ concentration in agonist-stimulated, intact human platelets by using Fluo-5N.

Journal of thrombosis and haemostasis : JTH 20110301

[Effects of tert-butylhydroquinone on oxidative stress in kidneys of diabetic mice].

Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20110301

Suppression of CFTR-mediated Cl secretion of airway epithelium in vitamin C-deficient mice.

Journal of Korean medical science 20110301

[Determination of antioxidant residues in polymer food package using gas chromatography].

Se pu = Chinese journal of chromatography 20110301

Identification of clinically used drugs that activate pregnane X receptors.

Drug metabolism and disposition: the biological fate of chemicals 20110101

Mathematical model of uptake and metabolism of arsenic(III) in human hepatocytes - Incorporation of cellular antioxidant response and threshold-dependent behavior.

BMC systems biology 20110101

Stabilization of Nrf2 protein by D3T provides protection against ethanol-induced apoptosis in PC12 cells.

PloS one 20110101

Attenuation of glomerular injury in diabetic mice with tert-butylhydroquinone through nuclear factor erythroid 2-related factor 2-dependent antioxidant gene activation.

American journal of nephrology 20110101

The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease.

Parkinson's disease 20110101

Cloud-point extraction and reversed-phase high-performance liquid chromatography for the determination of synthetic phenolic antioxidants in edible oils.

Journal of food science 20110101

Preventive effect of pine bark extract (flavangenol) on metabolic disease in Western diet-loaded tsumura suzuki obese diabetes mice.

Evidence-based complementary and alternative medicine : eCAM 20110101

Polyphenolic contents and antioxidant potential of stem bark extracts from Jatropha curcas (Linn).

International journal of molecular sciences 20110101

BTZO-15, an ARE-activator, ameliorates DSS- and TNBS-induced colitis in rats.

PloS one 20110101

Therapeutic potential and anti-amyloidosis mechanisms of tert-butylhydroquinone for Alzheimer's disease.

Journal of Alzheimer's disease : JAD 20110101

Activation of Nrf2-regulated glutathione pathway genes by ischemic preconditioning.

Oxidative medicine and cellular longevity 20110101

Antioxidant, antimicrobial and antiproliferative activities of five lichen species.

International journal of molecular sciences 20110101

Dietary saturated and monounsaturated fats protect against acute acetaminophen hepatotoxicity by altering fatty acid composition of liver microsomal membrane in rats.

Lipids in health and disease 20110101

Evidence for oxidative stress and defective antioxidant response in guinea pigs with tuberculosis.

PloS one 20110101

The Nrf1 CNC-bZIP protein is regulated by the proteasome and activated by hypoxia.

PloS one 20110101

Nuclear Factor-κB modulates cellular glutathione and prevents oxidative stress in cancer cells.

Cancer letters 20101218

Interplay between heme oxygenase-1 and the multifunctional transcription factor yin yang 1 in the inhibition of intimal hyperplasia.

Circulation research 20101210

Rational quantitative structure-activity relationship (RQSAR) screen for PXR and CAR isoform-specific nuclear receptor ligands.

Chemico-biological interactions 20101205

Tert-butylhydroquinone induces mitochondrial oxidative stress causing Nrf2 activation.

Cell biology and toxicology 20101201

Regulation of human carbonyl reductase 3 (CBR3; SDR21C2) expression by Nrf2 in cultured cancer cells.

Biochemistry 20101005

Multiple anticancer activities of EF24, a novel curcumin analog, on human ovarian carcinoma cells.

Reproductive sciences (Thousand Oaks, Calif.) 20101001

Direct amperometric determination of tert-butylhydroquinone in biodiesel.

Talanta 20100915

Induction of cereblon by NF-E2-related factor 2 in neuroblastoma cells exposed to hypoxia-reoxygenation.

Biochemical and biophysical research communications 20100903

Seasonal variation, chemical composition and antioxidant activity of Brazilian propolis samples.

Evidence-based complementary and alternative medicine : eCAM 20100901

After cellular internalization, quercetin causes Nrf2 nuclear translocation, increases glutathione levels, and prevents neuronal death against an oxidative insult.

Free radical biology & medicine 20100901

Voltammetric determination of tert-butylhydroquinone in biodiesel using a carbon paste electrode in the presence of surfactant.

Colloids and surfaces. B, Biointerfaces 20100901

Comparison of current docking tools for the simulation of inhibitor binding by the transmembrane domain of the sarco/endoplasmic reticulum calcium ATPase.

Biophysical chemistry 20100801

Direct spectroscopic observation of singlet oxygen quenching and kinetic studies of physical and chemical singlet oxygen quenching rate constants of synthetic antioxidants (BHA, BHT, and TBHQ) in methanol.

Journal of food science 20100801

The ERK1/2-hepatocyte nuclear factor 4alpha axis regulates human ABCC6 gene expression in hepatocytes.

The Journal of biological chemistry 20100723

An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds.

Journal of natural products 20100723

An autoregulatory loop between Nrf2 and Cul3-Rbx1 controls their cellular abundance.

The Journal of biological chemistry 20100709

Induction of the Nrf2-driven antioxidant response by tert-butylhydroquinone prevents ethanol-induced apoptosis in cranial neural crest cells.

Biochemical pharmacology 20100701

Determination of food grade antioxidants using microemulsion electrokinetic chromatography.

Electrophoresis 20100701

[Patch testing in patients with leg ulcers with special regard to modern wound products].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20100701

Proteomic analysis of Nrf2 deficient transgenic mice reveals cellular defence and lipid metabolism as primary Nrf2-dependent pathways in the liver.

Journal of proteomics 20100616

Antioxidant activity and chemical composition of the fractions from burdock leaves.

Journal of food science 20100601

Sodium 2-propenyl thiosulfate derived from garlic induces phase II detoxification enzymes in rat hepatoma H4IIE cells.

Nutrition research (New York, N.Y.) 20100601

Physical and functional interaction of sequestosome 1 with Keap1 regulates the Keap1-Nrf2 cell defense pathway.

The Journal of biological chemistry 20100528

The protective role of Nrf2 in streptozotocin-induced diabetic nephropathy.

Diabetes 20100401

Protection by Chrysanthemum zawadskii extract from liver damage of mice caused by carbon tetrachloride is maybe mediated by modulation of QR activity.

Nutrition research and practice 20100401

Comparing antioxidant effectiveness of natural and synthetic free radical scavengers in thermally-oxidized lard using DPPH method.

Journal of food science 20100401

The effect of tert-butylhydroquinone-induced oxidative stress in MDBK cells using XTT assay: implication of tert-butylhydroquinone-induced NADPH generating enzymes.

The Journal of veterinary medical science 20100301

Stabilization of transcription factor Nrf2 by tBHQ prevents oxidative stress-induced amyloid beta formation in NT2N neurons.

Biochimie 20100301

Paradoxical roles for antioxidants in tumor prevention and eradication.

Cancer biology & therapy 20100301

Keap1-Nrf2 activation in the presence and absence of DJ-1.

The European journal of neuroscience 20100301

Interaction between oxidative stress sensor Nrf2 and xenobiotic-activated aryl hydrocarbon receptor in the regulation of the human phase II detoxifying UDP-glucuronosyltransferase 1A10.

The Journal of biological chemistry 20100226

Transcriptional regulation of human carboxylesterase 1A1 by nuclear factor-erythroid 2 related factor 2 (Nrf2).

Biochemical pharmacology 20100115

The characteristics of performance and exhaust emissions of a diesel engine using a biodiesel with antioxidants.

Bioresource technology 20100101

Protective effect of tert-butylhydroquinone on the quinolinic-acid-induced toxicity in rat striatal slices: role of the Nrf2-antioxidant response element pathway.

Neuro-Signals 20100101

Critical cysteine residues of Kelch-like ECH-associated protein 1 in arsenic sensing and suppression of nuclear factor erythroid 2-related factor 2.

The Journal of pharmacology and experimental therapeutics 20100101

Antioxidant-induced phosphorylation of tyrosine 486 leads to rapid nuclear export of Bach1 that allows Nrf2 to bind to the antioxidant response element and activate defensive gene expression.

The Journal of biological chemistry 20100101

Nrf2 expression is regulated by epigenetic mechanisms in prostate cancer of TRAMP mice.

PloS one 20100101

[Effect of tBHQ and sulforaphane on Nrf2-ARE signaling pathway of Caco2 cells].

Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20100101

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

BMC medical genetics 20100101

Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury.

BMC neuroscience 20100101

Dietary phytosterols and phytostanols decrease cholesterol levels but increase blood pressure in WKY inbred rats in the absence of salt-loading.

Nutrition & metabolism 20100101

Peroxisome proliferator-activated receptors (PPARs)-independent functions of fish oil on glucose and lipid metabolism in diet-induced obese mice.

Lipids in health and disease 20100101

Stem cells for spinal cord regeneration: Current status.

Surgical neurology international 20100101

Effects of tert-butylhydroquinone on intestinal inflammatory response and apoptosis following traumatic brain injury in mice.

Mediators of inflammation 20100101

Antioxidant-induced modification of INrf2 cysteine 151 and PKC-delta-mediated phosphorylation of Nrf2 serine 40 are both required for stabilization and nuclear translocation of Nrf2 and increased drug resistance.

Journal of cell science 20091215

NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation.

Molecular pharmacology 20091201

Genomic analyses reveal a conserved glutathione homeostasis pathway in the invertebrate chordate Ciona intestinalis.

Physiological genomics 20091101

Oxidative stability and alpha-tocopherol retention in soybean oil with lemon seed extract (Citrus limon) under thermoxidation.

Natural product communications 20091101

[Protective effect of tert-butylhydroquinone on PC12 cells from neurotoxicity induced by manganese in vitro].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20091001

Enhanced bactericidal activity of enterocin AS-48 in combination with essential oils, natural bioactive compounds and chemical preservatives against Listeria monocytogenes in ready-to-eat salad.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090901

Identification and characterization of an Nrf2-mediated ARE upstream of the rat glutamate cysteine ligase catalytic subunit gene (GCLC).

Journal of cellular biochemistry 20090801

Distinct Nrf1/2-independent mechanisms mediate As 3+-induced glutamate-cysteine ligase subunit gene expression in murine hepatocytes.

Free radical biology & medicine 20090615

Kinetic study of the quenching reaction of singlet oxygen by common synthetic antioxidants (tert-butylhydroxyanisol, tert-di-butylhydroxytoluene, and tert-butylhydroquinone) as compared with alpha-tocopherol.

Journal of food science 20090601

Nrf2 activators provide neuroprotection against 6-hydroxydopamine toxicity in rat organotypic nigrostriatal cocultures.

Journal of neuroscience research 20090515

Induction of metallothionein I by arsenic via metal-activated transcription factor 1: critical role of C-terminal cysteine residues in arsenic sensing.

The Journal of biological chemistry 20090508

Inositol 1,4,5-triphosphate receptor-binding protein released with inositol 1,4,5-triphosphate (IRBIT) associates with components of the mRNA 3' processing machinery in a phosphorylation-dependent manner and inhibits polyadenylation.

The Journal of biological chemistry 20090417

Relationships between free radical scavenging and antioxidant activity in foods.

Journal of agricultural and food chemistry 20090408

Role of iron and hydroperoxides in the degradation of lycopene in oil-in-water emulsions.

Journal of agricultural and food chemistry 20090408

Skin fibroblast model to study an impaired glutathione synthesis: consequences of a genetic polymorphism on the proteome.

Brain research bulletin 20090406

Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice.

Toxicology letters 20090328

Lipophilicity data for some preservatives estimated by reversed-phase liquid chromatography and different computation methods.

Journal of chromatography. A 20090320

Role of the tumor suppressor PTEN in antioxidant responsive element-mediated transcription and associated histone modifications.

Molecular biology of the cell 20090315

tBHQ inhibits LPS-induced microglial activation via Nrf2-mediated suppression of p38 phosphorylation.

Biochemical and biophysical research communications 20090313

The Nrf1 CNC/bZIP protein is a nuclear envelope-bound transcription factor that is activated by t-butyl hydroquinone but not by endoplasmic reticulum stressors.

The Biochemical journal 20090301

Expression of sarco/endoplasmic reticulum Ca(2+) ATPase (SERCA) 3 proteins in two major conformational states in native human cell membranes.

Biochimica et biophysica acta 20090301

Curcumin, quercetin, and tBHQ modulate glutathione levels in astrocytes and neurons: importance of the glutamate cysteine ligase modifier subunit.

Journal of neurochemistry 20090301

Nrf2-regulated glutathione recycling independent of biosynthesis is critical for cell survival during oxidative stress.

Free radical biology & medicine 20090215

Simple ortho- and para-hydroquinones as compounds neuroprotective against oxidative stress in a manner associated with specific transcriptional activation.

Biochemical and biophysical research communications 20090206

HMOX1 and NQO1 genes are upregulated in response to contact sensitizers in dendritic cells and THP-1 cell line: role of the Keap1/Nrf2 pathway.

Toxicological sciences : an official journal of the Society of Toxicology 20090201

Role of hepatitis B virus X repression of C/EBPbeta activity in the down-regulation of glutathione S-transferase A2 gene: implications in other phase II detoxifying enzyme expression.

Xenobiotica; the fate of foreign compounds in biological systems 20090201

Oxidant stress stimulates expression of the human peroxiredoxin 6 gene by a transcriptional mechanism involving an antioxidant response element.

Free radical biology & medicine 20090115

Impaired nuclear Nrf2 translocation undermines the oxidative stress response in Friedreich ataxia.

PloS one 20090101

Regulation of shear-induced nuclear translocation of the Nrf2 transcription factor in endothelial cells.

Journal of biomedical science 20090101

Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.

PloS one 20090101

Methamphetamine induces dopamine D1 receptor-dependent endoplasmic reticulum stress-related molecular events in the rat striatum.

PloS one 20090101

Storage stability of sunflower oil with added natural antioxidant concentrate from sesame seed oil.

Journal of oleo science 20090101

Phosphorylation of Nrf2 at multiple sites by MAP kinases has a limited contribution in modulating the Nrf2-dependent antioxidant response.

PloS one 20090101

LAS0811: from combinatorial chemistry to activation of antioxidant response element.

Journal of biomedicine & biotechnology 20090101

Inflammatory mechanisms in ischemic stroke: therapeutic approaches.

Journal of translational medicine 20090101

Diets with corn oil and/or low protein increase acute acetaminophen hepatotoxicity compared to diets with beef tallow in a rat model.

Nutrition research and practice 20090101

Nordihydroguaiaretic acid activates the antioxidant pathway Nrf2/HO-1 and protects cerebellar granule neurons against oxidative stress.

Neuroscience letters 20081212

Regulatory potential for concerted modulation of Nrf2- and Nfkb1-mediated gene expression in inflammation and carcinogenesis.

British journal of cancer 20081209

Effect of homocysteine on calcium mobilization and platelet function in type 2 diabetes mellitus.

Journal of cellular and molecular medicine 20081201

Methyl methacrylate activates the Gsta1 promoter.

Journal of dental research 20081201

Proposed mechanism of inactivating Escherichia coli O157:H7 by ultra-high pressure in combination with tert-butylhydroquinone.

Journal of applied microbiology 20081201

Structure of influenza hemagglutinin in complex with an inhibitor of membrane fusion.

Proceedings of the National Academy of Sciences of the United States of America 20081118

Nuclear factor erythroid 2-related factor 2 protects against beta amyloid.

Molecular and cellular neurosciences 20081101

Induction of sulfiredoxin expression and reduction of peroxiredoxin hyperoxidation by the neuroprotective Nrf2 activator 3H-1,2-dithiole-3-thione.

Journal of neurochemistry 20081001

Dietary flavonoid (-)epicatechin stimulates phosphatidylinositol 3-kinase-dependent anti-oxidant response element activity and up-regulates glutathione in cortical astrocytes.

Journal of neurochemistry 20080901

Cinnamoyl-based Nrf2-activators targeting human skin cell photo-oxidative stress.

Free radical biology & medicine 20080815

The neuroprotective potential of phase II enzyme inducer on motor neuron survival in traumatic spinal cord injury in vitro.

Cellular and molecular neurobiology 20080801

Activation of Nrf2 by arsenite and monomethylarsonous acid is independent of Keap1-C151: enhanced Keap1-Cul3 interaction.

Toxicology and applied pharmacology 20080801

Metabolic kinetics of tert-butylhydroquinone and its metabolites in rat serum after oral administration by LC/ITMS.

Lipids 20080801

Activation of Nrf2 in defense against cadmium-induced oxidative stress.

Chemical research in toxicology 20080701

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2.

Carcinogenesis 20080601

STIM1 regulates acidic Ca2+ store refilling by interaction with SERCA3 in human platelets.

Biochemical pharmacology 20080601

Inactivation of barotolerant strains of Listeria monocytogenes and Escherichia coli O157:H7 by ultra high pressure and tert-butylhydroquinone combination.

Journal of microbiology (Seoul, Korea) 20080601

Markers of electrophilic stress caused by chemically reactive metabolites in human hepatocytes.

Drug metabolism and disposition: the biological fate of chemicals 20080501

Multiple nuclear localization signals function in the nuclear import of the transcription factor Nrf2.

The Journal of biological chemistry 20080404

Expression of MRP1 and GSTP1-1 modulate the acute cellular response to treatment with the chemopreventive isothiocyanate, sulforaphane.

Carcinogenesis 20080401

Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism.

Chemical research in toxicology 20080401

Dicarbonyls stimulate cellular protection systems in primary rat hepatocytes and show anti-inflammatory properties.

Annals of the New York Academy of Sciences 20080401

Nuclear factor-1 and metal transcription factor-1 synergistically activate the mouse metallothionein-1 gene in response to metal ions.

The Journal of biological chemistry 20080328

Determination of tertiary-butylhydroquinone and its metabolites in rat serum by liquid chromatography-ion trap mass spectrometry.

Lipids 20080301

Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid.

Toxicology and applied pharmacology 20080201

Phosphatidylinositol 4,5-bisphosphate enhances store-operated calcium entry through hTRPC6 channel in human platelets.

Biochimica et biophysica acta 20080101

Palm-based standard reference materials for iodine value and slip melting point.

Analytical chemistry insights 20080101

Nrf2 protects human bladder urothelial cells from arsenite and monomethylarsonous acid toxicity.

Toxicology and applied pharmacology 20071201

Melissoidesin G, a diterpenoid purified from Isodon melissoides, induces leukemic-cell apoptosis through induction of redox imbalance and exhibits synergy with other anticancer agents.

International journal of cancer 20071101

Capillary electrophoresis coupled with electrochemical detection using porous etched joint for determination of antioxidants.

Journal of chromatography. A 20071005

Antiaggregant effects of Arbutus unedo extracts in human platelets.

Journal of ethnopharmacology 20070905

NF-E2 related factor 2 activation and heme oxygenase-1 induction by tert-butylhydroquinone protect against deltamethrin-mediated oxidative stress in PC12 cells.

Chemical research in toxicology 20070901

Protection against chromium (VI)-induced oxidative stress and apoptosis by Nrf2. Recruiting Nrf2 into the nucleus and disrupting the nuclear Nrf2/Keap1 association.

Toxicological sciences : an official journal of the Society of Toxicology 20070701

Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury.

Neuroscience 20070615

Induction of phase I and II drug metabolism in rat small intestine and colon in vitro.

Drug metabolism and disposition: the biological fate of chemicals 20070601

Spectrophotometric determination of phenolic compounds by enzymatic and chemical methods--a comparison of structure--activity relationship.

Journal of agricultural and food chemistry 20070516

Nrf2-mediated protection against 6-hydroxydopamine.

Brain research 20070504

Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate.

Toxicological sciences : an official journal of the Society of Toxicology 20070401

Nrf2-Keap1 signaling pathway regulates human UGT1A1 expression in vitro and in transgenic UGT1 mice.

The Journal of biological chemistry 20070323

OKL38 is an oxidative stress response gene stimulated by oxidized phospholipids.

Journal of lipid research 20070301

Synthesis and antioxidant activity evaluation of new 7-aryl or 7-heteroarylamino-2,3-dimethylbenzo[b]thiophenes obtained by Buchwald-Hartwig C-N cross-coupling.

Bioorganic & medicinal chemistry 20070215

Allergic contact dermatitis from tertiary-butylhydroquinone and Laureth 12 in a hair dye.

Contact dermatitis 20070201

Chemoprotective and carcinogenic effects of tert-butylhydroquinone and its metabolites.

Current drug metabolism 20070101

Transcriptional profiling reveals barcode-like toxicogenomic responses in the zebrafish embryo.

Genome biology 20070101

Nrf2-dependent and -independent induction of ABC transporters ABCC1, ABCC2, and ABCG2 in HepG2 cells under oxidative stress.

Journal of experimental therapeutics & oncology 20070101

Genomic loci modulating the retinal transcriptome in wound healing.

Gene regulation and systems biology 20070101

Involvement of mitogen-activated protein kinases and protein kinase C in regulation of antioxidant response element activity in human keratinocytes.

Cancer letters 20061208

Induction of heme oxygenase-1 (HO-1) and NAD[P]H: quinone oxidoreductase 1 (NQO1) by a phenolic antioxidant, butylated hydroxyanisole (BHA) and its metabolite, tert-butylhydroquinone (tBHQ) in primary-cultured human and rat hepatocytes.

Pharmaceutical research 20061101

Nrf2 possesses a redox-sensitive nuclear exporting signal in the Neh5 transactivation domain.

The Journal of biological chemistry 20060915

The tert-butylhydroquinone-mediated activation of the human thioredoxin gene reveals a novel promoter structure.

The Biochemical journal 20060901

Arsenic induces NAD(P)H-quinone oxidoreductase I by disrupting the Nrf2 x Keap1 x Cul3 complex and recruiting Nrf2 x Maf to the antioxidant response element enhancer.

The Journal of biological chemistry 20060818

Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity.

Biochemical pharmacology 20060714

Regulation of CYP1A1 gene expression by the antioxidant tert-butylhydroquinone.

Drug metabolism and disposition: the biological fate of chemicals 20060701

Longevity in mice: is stress resistance a common factor?

Age (Dordrecht, Netherlands) 20060601

Involvement of p38 MAPK and Nrf2 in phenolic acid-induced P-form phenol sulfotransferase expression in human hepatoma HepG2 cells.

Carcinogenesis 20060501

Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis.

Journal of neurochemistry 20060501

Nuclear factor Nrf2 and antioxidant response element regulate NRH:quinone oxidoreductase 2 (NQO2) gene expression and antioxidant induction.

Free radical biology & medicine 20060401

Two distinct Ca2+ compartments show differential sensitivity to thrombin, ADP and vasopressin in human platelets.

Cellular signalling 20060301

[Protective effect of tert-butylhydroquinone on bone marrow cells in rats from cytotoxicity induced by benzene in vitro].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20060301

Use of phenolic compounds for sensitizing Listeria monocytogenes to high-pressure processing.

International journal of food microbiology 20060215

Involvement of phosphatidylinositol 3-kinase and extracellular-regulated kinase in hepatic stellate cell antioxidant response and myofibroblastic transdifferentiation.

Archives of biochemistry and biophysics 20060215

Oxidant stress suppresses CFTR expression.

American journal of physiology. Cell physiology 20060101

Effect of plant extracts on physicochemical properties of chicken breast meat cooked using conventional electric oven or microwave.

Poultry science 20060101

Activation of CYP1A1 gene expression during primary culture of mouse hepatocytes.

Toxicology 20051215

Estimated daily intakes of butylated hydroxyanisole (BHA), butylated hydroxytoluene (BHT) and tert-butyl hydroquinone (TBHQ) antioxidants in Korea.

Food additives and contaminants 20051201

A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20051102

A transient treatment of hippocampal neurons with alpha-tocopherol induces a long-lasting protection against oxidative damage via a genomic action.

Free radical biology & medicine 20051015

Butylhydroquinone protects cells genetically deficient in glutathione biosynthesis from arsenite-induced apoptosis without significantly changing their prooxidant status.

Toxicological sciences : an official journal of the Society of Toxicology 20051001

Increased nuclear factor-erythroid 2 p45-related factor 2 activity protects SH-SY5Y cells against oxidative damage.

Journal of neurochemistry 20051001

Specific patterns of electrophile adduction trigger Keap1 ubiquitination and Nrf2 activation.

The Journal of biological chemistry 20050909

Induction of the protective antioxidant response element pathway by 6-hydroxydopamine in vivo and in vitro.

Toxicological sciences : an official journal of the Society of Toxicology 20050901

Ca2+ accumulation into acidic organelles mediated by Ca2+- and vacuolar H+-ATPases in human platelets.

The Biochemical journal 20050815

Delayed mechanism for induction of gamma-glutamylcysteine synthetase heavy subunit mRNA stability by oxidative stress involving p38 mitogen-activated protein kinase signaling.

The Journal of biological chemistry 20050805

Induction of the Nrf2-driven antioxidant response confers neuroprotection during mitochondrial stress in vivo.

The Journal of biological chemistry 20050617

Determination and confirmation of five phenolic antioxidants in foods by LC/MS and GC/MS.

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20050601

Determination of antioxidants in cosmetics by micellar electrokinetic capillary chromatography with electrochemical detection.

Journal of chromatography. A 20050513

Serotonin glucuronidation by Ah receptor- and oxidative stress-inducible human UDP-glucuronosyltransferase (UGT) 1A6 in Caco-2 cells.

Biochemical pharmacology 20050501

Glucocorticoid receptor (GR)-associated SMRT binding to C/EBPbeta TAD and Nrf2 Neh4/5: role of SMRT recruited to GR in GSTA2 gene repression.

Molecular and cellular biology 20050501

Inactivation of barotolerant Listeria monocytogenes in sausage by combination of high-pressure processing and food-grade additives.

Journal of food protection 20050401

Dissecting tBHQ induced ARE-driven gene expression through long and short oligonucleotide arrays.

Physiological genomics 20050321

Transcriptional activation of the human Galphai2 gene promoter through nuclear factor-kappaB and antioxidant response elements.

The Journal of biological chemistry 20050318

tert-Butylhydroquinone is a novel aryl hydrocarbon receptor ligand.

Drug metabolism and disposition: the biological fate of chemicals 20050301

Down-regulation of aryl hydrocarbon receptor-regulated genes by tumor necrosis factor-alpha and lipopolysaccharide in murine hepatoma Hepa 1c1c7 cells.

Journal of pharmaceutical sciences 20050301

Different cytoprotective effect of antioxidants and change in the iron regulatory system in rodent cells exposed to paraquat or formaldehyde.

Toxicology 20050301

Induction of phase I, II and III drug metabolism/transport by xenobiotics.

Archives of pharmacal research 20050301

Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells.

Toxicological sciences : an official journal of the Society of Toxicology 20050201

Coordinate regulation of glutathione metabolism in astrocytes by Nrf2.

Biochemical and biophysical research communications 20050114

Potential neuroprotective effect of t-butylhydroquinone against neurotoxicity-induced by 1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine (2'-methyl-MPTP) in mice.

Journal of biochemical and molecular toxicology 20050101

Differential regulation of three genes encoding glutathione S-transferases in Schizosaccharomyces pombe.

Molecules and cells 20041231

Effect of electron beam irradiation and storage at 5 degrees C on thiobarbituric acid reactive substances and carbonyl contents in chicken breast meat infused with antioxidants and selected plant extracts.

Journal of agricultural and food chemistry 20041229

Expression of glutathione S-transferase P1-1 in leukemic cells is regulated by inducible AP-1 binding.

Cancer letters 20041228

Nrf3 negatively regulates antioxidant-response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.

The Journal of biological chemistry 20041203

Compartmentation of Nrf-2 redox control: regulation of cytoplasmic activation by glutathione and DNA binding by thioredoxin-1.

Toxicological sciences : an official journal of the Society of Toxicology 20041101

Phase II enzyme inducer, sulforaphane, inhibits UVB-induced AP-1 activation in human keratinocytes by a novel mechanism.

Molecular carcinogenesis 20041101

Optimization of a high-performance liquid chromatography system by artificial neural networks for separation and determination of antioxidants.

Journal of separation science 20041001

Hepatic stellate cells lack AP-1 responsiveness to electrophiles and phorbol 12-myristate-13-acetate.

Biochemical and biophysical research communications 20040924

Ceramide, an apoptotic rheostat, inhibits CCAAT/enhancer binding protein-beta and NF-E2-related factor-2 activation: the role in glutathione S-transferase A2 gene repression.

Drug metabolism and disposition: the biological fate of chemicals 20040901

Total phenolics and antioxidant activities of fenugreek, green tea, black tea, grape seed, ginger, rosemary, gotu kola, and ginkgo extracts, vitamin E, and tert-butylhydroquinone.

Journal of agricultural and food chemistry 20040811

Two pathways for store-mediated calcium entry differentially dependent on the actin cytoskeleton in human platelets.

The Journal of biological chemistry 20040709

PKC downstream of Pl3-kinase regulates peroxynitrite formation for Nrf2-mediated GSTA2 induction.

Archives of pharmacal research 20040701

Induction of metallothionein I by phenolic antioxidants requires metal-activated transcription factor 1 (MTF-1) and zinc.

The Biochemical journal 20040615

Ceramide negatively regulates glutathione S-transferase gene transactivation via repression of hepatic nuclear factor-1 that is degraded by the ubiquitin proteasome system.

Molecular pharmacology 20040601

Determining partition constants of polar organic molecules between the oil/interfacial and water/interfacial regions in emulsions: a combined electrochemical and spectrometric method.

Langmuir : the ACS journal of surfaces and colloids 20040413

Variable regulation of glutamate cysteine ligase subunit proteins affects glutathione biosynthesis in response to oxidative stress.

Archives of biochemistry and biophysics 20040301

The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.

Biochemical pharmacology 20040301

Nuclear factor E2-related factor 2-dependent antioxidant response element activation by tert-butylhydroquinone and sulforaphane occurring preferentially in astrocytes conditions neurons against oxidative insult.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20040204

Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap 'n' collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2): cross-interaction between AhR (aryl hydrocarbon receptor) and Nrf2 signal transduction.

The Biochemical journal 20040101

Identification of benzene metabolites in dermal fibroblasts as nonphenolic: regulation of cell viability, apoptosis, lipid peroxidation and expression of matrix metalloproteinase 1 and elastin by benzene metabolites.

Skin pharmacology and physiology 20040101

Increase of antioxidative potential by tert-butylhydroquinone protects against cell death associated with 6-hydroxydopamine-induced oxidative stress in neuroblastoma SH-SY5Y cells.

Brain research. Molecular brain research 20031126

Phosphorylation of Nrf2 at Ser40 by protein kinase C in response to antioxidants leads to the release of Nrf2 from INrf2, but is not required for Nrf2 stabilization/accumulation in the nucleus and transcriptional activation of antioxidant response element-mediated NAD(P)H:quinone oxidoreductase-1 gene expression.

The Journal of biological chemistry 20031107

A reassessment of the effects of luminal [Ca2+] on inositol 1,4,5-trisphosphate-induced Ca2+ release from internal stores.

The Journal of biological chemistry 20031010

Contribution of the Ah receptor to the phenolic antioxidant-mediated expression of human and rat UDP-glucuronosyltransferase UGT1A6 in Caco-2 and rat hepatoma 5L cells.

Biochemical pharmacology 20030901

Thioredoxin reductase in human hepatoma cells is transcriptionally regulated by sulforaphane and other electrophiles via an antioxidant response element.

The Journal of nutrition 20030901

Aqueous outflow-enhancing effect of tert-butylhydroquinone: involvement of AP-1 activation and MMP-3 expression.

Investigative ophthalmology & visual science 20030801

Positive and negative regulation of prostaglandin E2 biosynthesis in human colorectal carcinoma cells by cancer chemopreventive agents.

Biochemical pharmacology 20030701

Testicular toxicity of dibromoacetonitrile and possible protection by tertiary butylhydroquinone.

Pharmacological research 20030601

Cell death induced by the phenolic antioxidant tert-butylhydroquinone and its metabolite tert-butylquinone in human monocytic leukemia U937 cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030501

Thymoquinone is a potent superoxide anion scavenger.

Drug and chemical toxicology 20030501

Antioxidant activity of 3-dehydroshikimic acid in liposomes, emulsions, and bulk oil.

Journal of agricultural and food chemistry 20030423

Enhancement of ATRA-induced cell differentiation by inhibition of calcium accumulation into the endoplasmic reticulum: cross-talk between RAR alpha and calcium-dependent signaling.

Blood 20030415

Pivotal role of electrophilicity in glutathione S-transferase induction by tert-butylhydroquinone.

Biochemistry 20030415

Coordinate regulation of glutathione biosynthesis and release by Nrf2-expressing glia potently protects neurons from oxidative stress.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415

Identification of the NF-E2-related factor-2-dependent genes conferring protection against oxidative stress in primary cortical astrocytes using oligonucleotide microarray analysis.

The Journal of biological chemistry 20030404

Differential responses from seven mammalian cell lines to the treatments of detoxifying enzyme inducers.

Life sciences 20030404

Hydrogen peroxide- and cell-density-regulated expression of NADH-cytochrome b5 reductase in HeLa cells.

Journal of bioenergetics and biomembranes 20030401

Thioredoxin-dependent redox regulation of the antioxidant responsive element (ARE) in electrophile response.

Oncogene 20030327

Cyclooxygenase inhibitory and antioxidant compounds from crabapple fruits.

Journal of agricultural and food chemistry 20030326

Role of NAD(P)H:quinone oxidoreductase in the progression of neuronal cell death in vitro and following cerebral ischaemia in vivo.

Journal of neurochemistry 20030301

Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome.

The Journal of biological chemistry 20030214

Patch testing with the irritant sodium lauryl sulfate (SLS) is useful in interpreting weak reactions to contact allergens as allergic or irritant.

Contact dermatitis 20030201

Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress.

Molecular pharmacology 20021101

Pharmacogenomics, regulation and signaling pathways of phase I and II drug metabolizing enzymes.

Current drug metabolism 20021001

Differential gene expression patterns revealed by oligonucleotide versus long cDNA arrays.

Toxicological sciences : an official journal of the Society of Toxicology 20021001

Role of AP-1 in the coordinate induction of rat glutamate-cysteine ligase and glutathione synthetase by tert-butylhydroquinone.

The Journal of biological chemistry 20020920

Inhibition of lipid peroxidation and structure-activity-related studies of the dietary constituents anthocyanins, anthocyanidins, and catechins.

Journal of agricultural and food chemistry 20020911

Identification of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene. Revision of the ARE consensus sequence.

The Journal of biological chemistry 20020823

Copper redox-dependent activation of 2-tert-butyl(1,4)hydroquinone: formation of reactive oxygen species and induction of oxidative DNA damage in isolated DNA and cultured rat hepatocytes.

Mutation research 20020725

Polymorphism in the 5'-flanking region of human glutamate-cysteine ligase modifier subunit gene is associated with myocardial infarction.

Circulation 20020625

In vitro induction of the anticarcinogenic marker enzyme, quinone reductase, in human hepatoma cells by food extracts.

Cancer letters 20020606

Activation of the antioxidant response element in primary cortical neuronal cultures derived from transgenic reporter mice.

Journal of neurochemistry 20020601

Kinetic method for determining antioxidant distributions in model food emulsions: distribution constants of t-butylhydroquinone in mixtures of octane, water, and a nonionic emulsifier.

Journal of agricultural and food chemistry 20020522

Glutamate-cysteine ligase modifier subunit: mouse Gclm gene structure and regulation by agents that cause oxidative stress.

Biochemical pharmacology 20020501

Characterization, quantification, and bioactivities of anthocyanins in Cornus species.

Journal of agricultural and food chemistry 20020424

Promoting effects of combined antioxidant and sodium nitrite treatment on forestomach carcinogenesis in rats after initiation with N-methyl-N'-nitro-N-nitrosoguanidine.

Cancer letters 20020408

[Simultaneous determination of five antioxidants in food by HPLC with fluorescence detection].

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20020401

Influence of redox-active compounds and PXR-activators on human MRP1 and MRP2 gene expression.

Toxicology 20020227

Ability of surfactant micelles to alter the partitioning of phenolic antioxidants in oil-in-water emulsions.

Journal of agricultural and food chemistry 20020227

Chemoprotection by phenolic antioxidants. Inhibition of tumor necrosis factor alpha induction in macrophages.

The Journal of biological chemistry 20020125

Differential induction of mafF, mafG and mafK expression by electrophile-response-element activators.

The Biochemical journal 20020115

Influence of t-butylhydroquinone and beta-naphthoflavone on formation and transport of 4-methylumbelliferone glucuronide in Caco-2/TC-7 cell monolayers.

Biochemical pharmacology 20020115

Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form.

The Journal of biological chemistry 20020111

Microarray analysis reveals an antioxidant responsive element-driven gene set involved in conferring protection from an oxidative stress-induced apoptosis in IMR-32 cells.

The Journal of biological chemistry 20020104

Time-dependent changes in ARE-driven gene expression by use of a noise-filtering process for microarray data.

Physiological genomics 20020101

Cell-based studies reveal differences in glutathione S-transferase induction between oltipraz and tert-butylhydroquinone.

Journal of biochemical and molecular toxicology 20020101

Regulation of the glyoxalase pathway in human brain microvascular endothelium: effects of troglitazone and tertiary butylhydroperoxide.

Endothelium : journal of endothelial cell research 20020101

A novel function of sphingosine-1-phosphate to activate a non-selective cation channel in human endothelial cells.

The Journal of physiology 20011201

Comparison of the bioactivity of two glucoraphanin hydrolysis products found in broccoli, sulforaphane and sulforaphane nitrile.

Journal of agricultural and food chemistry 20011201

Functional characterization of transcription regulators that interact with the electrophile response element.

Biochemical and biophysical research communications 20011123

Troglitazone selectively inhibits glyoxalase I gene expression.

Diabetologia 20011101

[Extraction of the antioxidative substances from Chinese rose and its antioxidative effect on lard].

Wei sheng yan jiu = Journal of hygiene research 20011101

The impaired glutathione system and its up-regulation by sulforaphane in vascular smooth muscle cells from spontaneously hypertensive rats.

Journal of hypertension 20011001

Degradation products of cyanidin glycosides from tart cherries and their bioactivities.

Journal of agricultural and food chemistry 20011001

Regulation of the rat glutathione S-transferase A2 gene by glucocorticoids: involvement of both the glucocorticoid and pregnane X receptors.

Molecular pharmacology 20010901

Cyclooxygenase inhibitory and antioxidant cyanidin glycosides in cherries and berries.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20010901

2,5-Di-tert-butyl-1,4-hydroquinone enhances cell transformation accompanied by an increase in intracellular free calcium ion concentration.

Cancer letters 20010726

Functional characterization and role of INrf2 in antioxidant response element-mediated expression and antioxidant induction of NAD(P)H:quinone oxidoreductase1 gene.

Oncogene 20010628

Phosphatidylinositol 3-kinase, not extracellular signal-regulated kinase, regulates activation of the antioxidant-responsive element in IMR-32 human neuroblastoma cells.

The Journal of biological chemistry 20010608

Activation of phosphatidylinositol 3-kinase and Akt by tert-butylhydroquinone is responsible for antioxidant response element-mediated rGSTA2 induction in H4IIE cells.

Molecular pharmacology 20010501

Estimates of the theoretical maximum daily intake of phenolic antioxidants BHA, BHT and TBHQ in Brazil.

Food additives and contaminants 20010501

Up-regulation of transporters of the MRP family by drugs and toxins.

Toxicology letters 20010331

Reactive oxygen species-related induction of multidrug resistance-associated protein 2 expression in primary hepatocytes exposed to sulforaphane.

Biochemical and biophysical research communications 20010323

Differential sensitivities of the MRP gene family and gamma-glutamylcysteine synthetase to prooxidants in human colorectal carcinoma cell lines with different p53 status.

Biochemical pharmacology 20010301

Preferential expression of antioxidant response element mediated gene expression in astrocytes.

Journal of neurochemistry 20010301

Identification of alpha-tocopherol oxidation products in triolein at elevated temperatures.

Journal of agricultural and food chemistry 20010301

Synthesis and antiperoxidant activity of new phenolic O-glycosides.

Carbohydrate research 20010227

Lack of an endothelial store-operated Ca2+ current impairs agonist-dependent vasorelaxation in TRP4-/- mice.

Nature cell biology 20010201

Tyrphostin [correction of Tryphostin] AG879, a tyrosine kinase inhibitor: prevention of transcriptional activation of the electrophile and the aromatic hydrocarbon response elements.

Biochemical pharmacology 20010115

Nrf2-dependent activation of the antioxidant responsive element by tert-butylhydroquinone is independent of oxidative stress in IMR-32 human neuroblastoma cells.

Biochemical and biophysical research communications 20010112

The double-stranded RNA-activated protein kinase PKR is dispensable for regulation of translation initiation in response to either calcium mobilization from the endoplasmic reticulum or essential amino acid starvation.

Biochemical and biophysical research communications 20010112

Evaluation of the TOPKAT system for predicting the carcinogenicity of chemicals.

Environmental and molecular mutagenesis 20010101

Induction of xenobiotic enzymes by the MAP kinase pathway and the antioxidant or electrophile response element (ARE/EpRE).

Drug metabolism reviews 20010101

Induction of heme oxygenase-1 expression in macrophages by diesel exhaust particle chemicals and quinones via the antioxidant-responsive element.

Journal of immunology (Baltimore, Md. : 1950) 20000915

Mechanism of heme oxygenase-1 gene activation by cadmium in MCF-7 mammary epithelial cells. Role of p38 kinase and Nrf2 transcription factor.

The Journal of biological chemistry 20000908

Inducers of gamma-glutamylcysteine synthetase and their effects on glutathione synthetase expression.

Biochimica et biophysica acta 20000907

Molecular mechanisms of butylated hydroxylanisole-induced toxicity: induction of apoptosis through direct release of cytochrome c.

Molecular pharmacology 20000801

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene.

The Journal of biological chemistry 19990910

Chemoprevention of heterocyclic amine-induced carcinogenesis by phenolic compounds in rats.

Cancer letters 19990901

Induction of human UDP glucuronosyltransferases (UGT1A6, UGT1A9, and UGT2B7) by t-butylhydroquinone and 2,3,7,8-tetrachlorodibenzo-p-dioxin in Caco-2 cells.

Drug metabolism and disposition: the biological fate of chemicals 19990501

Isoform-specific induction of a human aldo-keto reductase by polycyclic aromatic hydrocarbons (PAHs), electrophiles, and oxidative stress: implications for the alternative pathway of PAH activation catalyzed by human dihydrodiol dehydrogenase.

Cancer research 19990201

Human NAD(P)H:quinone oxidoreductase induction in human hepatoma cells after exposure to industrial acrylates, phenolics, and metals.

Drug metabolism and disposition: the biological fate of chemicals 19970201

Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE).

Molecular medicine (Cambridge, Mass.) 19951101

Electrophile and antioxidant regulation of enzymes that detoxify carcinogens.

Proceedings of the National Academy of Sciences of the United States of America 19950912

Regulation of the Ah gene battery via Ah receptor-dependent and independent processes in cultured adult rat hepatocytes.

Drug metabolism and disposition: the biological fate of chemicals 19950601

Regulation of [Ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[1,2-b]indole in mouse hepatoma cell lines.

Carcinogenesis 19941001