S-Adenosyl-l-methionine
Title | Journal |
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Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice. | The Journal of nutritional biochemistry 20171001 |
Biochemical Characterization and Structural Basis of Reactivity and Regioselectivity Differences between Burkholderia thailandensis and Burkholderia glumae 1,6-Didesmethyltoxoflavin N-Methyltransferase. | Biochemistry 20170801 |
PR Domain-containing Protein 7 (PRDM7) Is a Histone 3 Lysine 4 Trimethyltransferase. | The Journal of biological chemistry 20160624 |
Vimentin-Mediated Steroidogenesis Induced by Phthalate Esters: Involvement of DNA Demethylation and Nuclear Factor κB. | PloS one 20160101 |
Alternatively Spliced Methionine Synthase in SH-SY5Y Neuroblastoma Cells: Cobalamin and GSH Dependence and Inhibitory Effects of Neurotoxic Metals and Thimerosal. | Oxidative medicine and cellular longevity 20160101 |
Identification of Small Molecule Inhibitors of Human As(III) S-Adenosylmethionine Methyltransferase (AS3MT). | Chemical research in toxicology 20151221 |
The effect of a methyl-deficient diet on the global DNA methylation and the DNA methylation regulatory pathways. | Journal of applied toxicology : JAT 20151201 |
A fragment-based approach to identifying S-adenosyl-l-methionine -competitive inhibitors of catechol O-methyl transferase (COMT). | Journal of medicinal chemistry 20140626 |
Arsenic trioxide attenuates the invasion potential of human liver cancer cells through the demethylation-activated microRNA-491. | Toxicology letters 20140605 |
Decreased glutathione and elevated hair mercury levels are associated with nutritional deficiency-based autism in Oman. | Experimental biology and medicine (Maywood, N.J.) 20140601 |
The functions of crucial cysteine residues in the arsenite methylation catalyzed by recombinant human arsenic (III) methyltransferase. | PloS one 20140101 |
The role of catechol-O-methyltransferase in catechol-enhanced erythroid differentiation of K562 cells. | Toxicology and applied pharmacology 20131215 |
Alterations in hepatic metabolism of sulfur amino acids in non-obese type-2 diabetic Goto-Kakizaki rats. | Chemico-biological interactions 20130705 |
Structure-guided discovery of the metabolite carboxy-SAM that modulates tRNA function. | Nature 20130606 |
Role of epigenetic and miR-22 and miR-29b alterations in the downregulation of Mat1a and Mthfr genes in early preneoplastic livers in rats induced by 2-acetylaminofluorene. | Molecular carcinogenesis 20130401 |
Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease. | Hepatology (Baltimore, Md.) 20130201 |
Rapid equilibrium kinetic analysis of arsenite methylation catalyzed by recombinant human arsenic (+3 oxidation state) methyltransferase (hAS3MT). | The Journal of biological chemistry 20121109 |
Allosteric communication between the pyridoxal 5'-phosphate (PLP) and heme sites in the H2S generator human cystathionine β-synthase. | The Journal of biological chemistry 20121102 |
Radical SAM enzymes in the biosynthesis of sugar-containing natural products. | Biochimica et biophysica acta 20121101 |
Mechanistic studies of the radical SAM enzyme spore photoproduct lyase (SPL). | Biochimica et biophysica acta 20121101 |
Radical AdoMet enzymes in complex metal cluster biosynthesis. | Biochimica et biophysica acta 20121101 |
Biotin synthase: insights into radical-mediated carbon-sulfur bond formation. | Biochimica et biophysica acta 20121101 |
Structural diversity in the AdoMet radical enzyme superfamily. | Biochimica et biophysica acta 20121101 |
S-adenosylmethionine (SAMe) therapy in liver disease: a review of current evidence and clinical utility. | Journal of hepatology 20121101 |
Identification and function of auxiliary iron-sulfur clusters in radical SAM enzymes. | Biochimica et biophysica acta 20121101 |
Radical SAM enzymes involved in the biosynthesis of purine-based natural products. | Biochimica et biophysica acta 20121101 |
High-energy compounds promote physiological processing of Alzheimer's amyloid-β precursor protein and boost cell survival in culture. | Journal of neurochemistry 20121101 |
Methionine adenosyltransferase I/III deficiency: neurological manifestations and relevance of S-adenosylmethionine. | Molecular genetics and metabolism 20121101 |
The epigenetic effects of a high prenatal folate intake in male mouse fetuses exposed in utero to arsenic. | Toxicology and applied pharmacology 20121101 |
Radical SAM enzymes in methylation and methylthiolation. | Metallomics : integrated biometal science 20121101 |
A RubisCO-like protein links SAM metabolism with isoprenoid biosynthesis. | Nature chemical biology 20121101 |
Structure analysis of geranyl pyrophosphate methyltransferase and the proposed reaction mechanism of SAM-dependent C-methylation. | Acta crystallographica. Section D, Biological crystallography 20121101 |
Structural characterization of a modification subunit of a putative type I restriction enzyme from Vibrio vulnificus YJ016. | Acta crystallographica. Section D, Biological crystallography 20121101 |
Covalent intermediate in the catalytic mechanism of the radical S-adenosyl-L-methionine methyl synthase RlmN trapped by mutagenesis. | Journal of the American Chemical Society 20121031 |
The BioC O-methyltransferase catalyzes methyl esterification of malonyl-acyl carrier protein, an essential step in biotin synthesis. | The Journal of biological chemistry 20121026 |
Synthetic biotechnology to study and engineer ribosomal bottromycin biosynthesis. | Chemistry & biology 20121026 |
S-adenosylmethionine-dependent protein methylation is required for expression of selenoprotein P and gluconeogenic enzymes in HepG2 human hepatocytes. | The Journal of biological chemistry 20121019 |
Mechanism and significance of changes in glutamate-cysteine ligase expression during hepatic fibrogenesis. | The Journal of biological chemistry 20121019 |
Human liver methionine cycle: MAT1A and GNMT gene resequencing, functional genomics, and hepatic genotype-phenotype correlation. | Drug metabolism and disposition: the biological fate of chemicals 20121001 |
Methylation of arsenic by recombinant human wild-type arsenic (+3 oxidation state) methyltransferase and its methionine 287 threonine (M287T) polymorph: Role of glutathione. | Toxicology and applied pharmacology 20121001 |
An ABC transporter complex containing S-adenosylmethionine (SAM)-induced ATP-binding protein is involved in antibiotics production and SAM signaling in Streptomyces coelicolor M145. | Biotechnology letters 20121001 |
Blood biomarkers of methylation in Down syndrome and metabolic simulations using a mathematical model. | Molecular nutrition & food research 20121001 |
The comprehensive effects of hyperlipidemia and hyperhomocysteinemia on pathogenesis of atherosclerosis and DNA hypomethylation in ApoE-/- mice. | Acta biochimica et biophysica Sinica 20121001 |
Radical SAM-dependent carbon insertion into the nitrogenase M-cluster. | Science (New York, N.Y.) 20120928 |
Betaine homocysteine methyltransferase is active in the mouse blastocyst and promotes inner cell mass development. | The Journal of biological chemistry 20120921 |
Metaboloepigenetics: interrelationships between energy metabolism and epigenetic control of gene expression. | Journal of cellular physiology 20120901 |
S-adenosyl methionine regulates ubiquitin-conjugating enzyme 9 protein expression and sumoylation in murine liver and human cancers. | Hepatology (Baltimore, Md.) 20120901 |
S-adenosyl-L-methionine (SAMe) for smoking abstinence: a randomized clinical trial. | Journal of alternative and complementary medicine (New York, N.Y.) 20120901 |
Novel protective mechanisms for S-adenosyl-L-methionine against acetaminophen hepatotoxicity: improvement of key antioxidant enzymatic function. | Toxicology letters 20120803 |
Nutrition and epigenetics: an interplay of dietary methyl donors, one-carbon metabolism and DNA methylation. | The Journal of nutritional biochemistry 20120801 |
Roles of the synergistic reductive O-methyltransferase GilM and of O-methyltransferase GilMT in the gilvocarcin biosynthetic pathway. | Journal of the American Chemical Society 20120801 |
Structure of Aeropyrum pernix fibrillarin in complex with natively bound S-adenosyl-L-methionine at 1.7 Å resolution. | Acta crystallographica. Section F, Structural biology and crystallization communications 20120801 |
Identification of an S-adenosylmethionine (SAM) dependent arsenic methyltransferase in Danio rerio. | Toxicology and applied pharmacology 20120715 |
S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice. | Neurobiology of aging 20120701 |
Relationships among biomarkers of one-carbon metabolism. | Molecular biology reports 20120701 |
Crystal and solution structures of methyltransferase RsmH provide basis for methylation of C1402 in 16S rRNA. | Journal of structural biology 20120701 |
Nutritional B vitamin deficiency disrupts lipid metabolism causing accumulation of proatherogenic lipoproteins in the aorta adventitia of ApoE null mice. | Molecular nutrition & food research 20120701 |
Supra-physiological folic acid concentrations induce aberrant DNA methylation in normal human cells in vitro. | Epigenetics 20120701 |
Biomarkers of the one-carbon pathway in association with congenital diaphragmatic hernia. | Birth defects research. Part A, Clinical and molecular teratology 20120701 |
Folates and S-adenosylmethionine for major depressive disorder. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20120701 |
DNA extraction method with improved efficiency and specificity using DNA methyltransferase and 'click' chemistry. | Analytical biochemistry 20120615 |
Conformational properties of nine purified cystathionine β-synthase mutants. | Biochemistry 20120612 |
Resurgence of serine: an often neglected but indispensable amino Acid. | The Journal of biological chemistry 20120608 |
A novel genome-based approach correlates TMPRSS3 overexpression in ovarian cancer with DNA hypomethylation. | Gynecologic oncology 20120601 |
Mallory-Denk bodies form when EZH2/H3K27me3 fails to methylate DNA in the nuclei of human and mice liver cells. | Experimental and molecular pathology 20120601 |
The association between plasma homocysteine levels, methylation capacity and incident osteoporotic fractures. | Bone 20120601 |
Methionine sulfoxide reductase contributes to meeting dietary methionine requirements. | Archives of biochemistry and biophysics 20120601 |
Structure and folding of a rare, natural kink turn in RNA with an A*A pair at the 2b*2n position. | RNA (New York, N.Y.) 20120601 |
Is protein methylation in the human lens a result of non-enzymatic methylation by S-adenosylmethionine? | Experimental eye research 20120601 |
Significantly enhanced production of acarbose in fed-batch fermentation with the addition of S-adenosylmethionine. | Journal of microbiology and biotechnology 20120601 |
Dietary supplement drug therapies for depression. | Journal of psychosocial nursing and mental health services 20120601 |
Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder. | The Journal of clinical psychiatry 20120601 |
Characterization of yatakemycin gene cluster revealing a radical S-adenosylmethionine dependent methyltransferase and highlighting spirocyclopropane biosynthesis. | Journal of the American Chemical Society 20120530 |
A selenium-based click AdoMet analogue for versatile substrate labeling with wild-type protein methyltransferases. | Chembiochem : a European journal of chemical biology 20120529 |
Conformational heterogeneity of the SAM-I riboswitch transcriptional ON state: a chaperone-like role for S-adenosyl methionine. | Journal of molecular biology 20120518 |
Riboswitch structure in the ligand-free state. | Wiley interdisciplinary reviews. RNA 20120501 |
Development of rationally designed DNA N6 adenine methyltransferase inhibitors. | Bioorganic & medicinal chemistry letters 20120501 |
Early changes in the liver-soluble proteome from mice fed a nonalcoholic steatohepatitis inducing diet. | Proteomics 20120501 |
Nutritional interventions to prevent and treat osteoarthritis. Part II: focus on micronutrients and supportive nutraceuticals. | PM & R : the journal of injury, function, and rehabilitation 20120501 |
Radical-mediated enzymatic methylation: a tale of two SAMS. | Accounts of chemical research 20120417 |
Structure of geranyl diphosphate C-methyltransferase from Streptomyces coelicolor and implications for the mechanism of isoprenoid modification. | Biochemistry 20120410 |
Bioorthogonal profiling of protein methylation using azido derivative of S-adenosyl-L-methionine. | Journal of the American Chemical Society 20120404 |
Changes in IL12A methylation pattern in livers from mice fed DDC. | Experimental and molecular pathology 20120401 |
Post-translational stabilization of thiopurine S-methyltransferase by S-adenosyl-L-methionine reveals regulation of TPMT*1 and *3C allozymes. | Biochemical pharmacology 20120401 |
[Comparative evaluation of clinical efficacy of drugs remaxol and ademetionine in patients with acute ethanol poisoning complicated by the toxic damage of the liver]. | Georgian medical news 20120401 |
Determinants of the essential one-carbon metabolism metabolites, homocysteine, S-adenosylmethionine, S-adenosylhomocysteine and folate, in cerebrospinal fluid. | Clinical chemistry and laboratory medicine 20120324 |
Fluorescence imaging of cellular metabolites with RNA. | Science (New York, N.Y.) 20120309 |
S-adenosylmethionine treatment in methionine adenosyltransferase deficiency, a case report. | Molecular genetics and metabolism 20120301 |
Enhanced co-production of S-adenosylmethionine and glutathione by an ATP-oriented amino acid addition strategy. | Bioresource technology 20120301 |
High-resolution structures of complexes of plant S-adenosyl-L-homocysteine hydrolase (Lupinus luteus). | Acta crystallographica. Section D, Biological crystallography 20120301 |
Catechol-O-methyltransferase in complex with substituted 3'-deoxyribose bisubstrate inhibitors. | Acta crystallographica. Section D, Biological crystallography 20120301 |
Sulfamethazine suppresses epigenetic silencing in Arabidopsis by impairing folate synthesis. | The Plant cell 20120301 |
The radical SAM enzyme AlbA catalyzes thioether bond formation in subtilosin A. | Nature chemical biology 20120226 |
A combined model of hepatic polyamine and sulfur amino acid metabolism to analyze S-adenosyl methionine availability. | Amino acids 20120201 |
Effects of S-adenosylmethionine augmentation of serotonin-reuptake inhibitor antidepressants on cognitive symptoms of major depressive disorder. | Journal of affective disorders 20120201 |
The effect of SAMe and betaine on Hepa 1-6, C34 and E47 liver cell survival in vitro. | Experimental and molecular pathology 20120201 |
Nutritional influences on epigenetics and age-related disease. | The Proceedings of the Nutrition Society 20120201 |
Methylation of catechins and procyanidins by rat and human catechol-O-methyltransferase: metabolite profiling and molecular modeling studies. | Drug metabolism and disposition: the biological fate of chemicals 20120201 |
Alcohol intake and folate antagonism via CYP2E1 and ALDH1: effects on oral carcinogenesis. | Medical hypotheses 20120201 |
Two patients with hepatic mtDNA depletion syndromes and marked elevations of S-adenosylmethionine and methionine. | Molecular genetics and metabolism 20120201 |
Effects of S-adenosylmethionine and methylthioadenosine on inflammation-induced colon cancer in mice. | Carcinogenesis 20120201 |
Atomic-level insights into metabolite recognition and specificity of the SAM-II riboswitch. | RNA (New York, N.Y.) 20120201 |
The role of S-adenosylmethionine in preventing oxaliplatin-induced liver toxicity: a retrospective analysis in metastatic colorectal cancer patients treated with bevacizumab plus oxaliplatin-based regimen. | Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 20120101 |
Dietary supplementation with S-adenosyl methionine delayed amyloid-β and tau pathology in 3xTg-AD mice. | Journal of Alzheimer's disease : JAD 20120101 |
Design, synthesis and in vitro evaluation of novel bivalent S-adenosylmethionine analogues. | Bioorganic & medicinal chemistry letters 20120101 |
SAMe and HuR in liver physiology: usefulness of stem cells in hepatic differentiation research. | Methods in molecular biology (Clifton, N.J.) 20120101 |
Low-dose methotrexate inhibits methionine S-adenosyltransferase in vitro and in vivo. | Molecular medicine (Cambridge, Mass.) 20120101 |
DNA methyltransferases: mechanistic models derived from kinetic analysis. | Critical reviews in biochemistry and molecular biology 20120101 |
S-adenosylmethionine does not reduce ischaemia-reperfusion injury to a marginal liver graft in an in vivo experiment. | Hepato-gastroenterology 20120101 |
In vitro study of uptake and synthesis of creatine and its precursors by cerebellar granule cells and astrocytes suggests some hypotheses on the physiopathology of the inherited disorders of creatine metabolism. | BMC neuroscience 20120101 |
Arsenic induces functional re-expression of estrogen receptor α by demethylation of DNA in estrogen receptor-negative human breast cancer. | PloS one 20120101 |
[Peculiarities of pharmacological correction of acute toxic hepatopathies in patients with severe forms of acute alcohol intoxication]. | Klinicheskaia meditsina 20120101 |
The different induction mechanisms of growth arrest DNA damage inducible gene 45 β in human hepatoma cell lines. | Chemotherapy 20120101 |
[Characteristics of the pharmacological treatment of toxic liver damage in patients with an alcohol abused syndrome and an acute severe ethanol poison]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101 |
Dimethylarginines, homocysteine metabolism, and cerebrospinal fluid markers for Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20120101 |
[Intrahepatic induction of endogenous S-adenosyl-L-methionine against the background of various ways of administration of methionine-succinate complex and its role in drug-induced liver lesion correction]. | Vestnik Rossiiskoi akademii meditsinskikh nauk 20120101 |
Reprogramming of gene expression during compression wood formation in pine: coordinated modulation of S-adenosylmethionine, lignin and lignan related genes. | BMC plant biology 20120101 |
[Principles and perspectives of primary biliary cirrhosis therapy]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20120101 |
[Clinical signs of endothelial disorders in patients with severe sepsis]. | Anesteziologiia i reanimatologiia 20120101 |
Identification of new ligands for the methionine biosynthesis transcriptional regulator (MetJ) by FAC-MS. | Journal of molecular microbiology and biotechnology 20120101 |
[Hepatoprotectors in addictive medicine]. | Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova 20120101 |
[Pathogenetic therapy of metabolic syndrome at the stage of visceral lesions]. | Klinicheskaia meditsina 20120101 |
Genes encoding Cher-TPR fusion proteins are predominantly found in gene clusters encoding chemosensory pathways with alternative cellular functions. | PloS one 20120101 |
RlmN and AtsB as models for the overproduction and characterization of radical SAM proteins. | Methods in enzymology 20120101 |
Inhibition of P-glycoprotein-mediated transport by S-adenosylmethionine and cynarin in multidrug-resistant human uterine sarcoma MES-SA/Dx5 cells. | Journal of biological regulators and homeostatic agents 20120101 |
Genetic modification and bioprocess optimization for S-Adenosyl-L-methionine biosynthesis. | Sub-cellular biochemistry 20120101 |
CYP2E1 potentiates toxicity in obesity and after chronic ethanol treatment. | Drug metabolism and drug interactions 20120101 |
Mechanism of isoprenylcysteine carboxyl methylation from the crystal structure of the integral membrane methyltransferase ICMT. | Molecular cell 20111223 |
Synthesis of an azide-bearing N-mustard analogue of S-adenosyl-L-methionine. | The Journal of organic chemistry 20111216 |
Arabidopsis calcium-binding mitochondrial carrier proteins as potential facilitators of mitochondrial ATP-import and plastid SAM-import. | FEBS letters 20111215 |
Cfr and RlmN contain a single [4Fe-4S] cluster, which directs two distinct reactivities for S-adenosylmethionine: methyl transfer by SN2 displacement and radical generation. | Journal of the American Chemical Society 20111214 |
Pneumocystis S-adenosylmethionine transport: a potential drug target. | American journal of respiratory cell and molecular biology 20111201 |
Homocysteine-induced cardiomyocyte apoptosis and plasma membrane flip-flop are independent of S-adenosylhomocysteine: a crucial role for nuclear p47(phox). | Molecular and cellular biochemistry 20111201 |
S-Adenosylmethionine-dependent alkylation reactions: when are radical reactions used? | Bioorganic chemistry 20111201 |
Biochemical disorders associated with antiproliferative effect of dehydroepiandrosterone in hepatoma cells as revealed by LC-based metabolomics. | Biochemical pharmacology 20111201 |
Structural characterization of BVU_3255, a methyltransferase from human intestine antibiotic resistant pathogen Bacteroides vulgatus. | Journal of structural biology 20111201 |
Proteomic analysis of a sea-ice diatom: salinity acclimation provides new insight into the dimethylsulfoniopropionate production pathway. | Plant physiology 20111201 |
The PRPP synthetase spectrum: what does it demonstrate about nucleotide syndromes? | Nucleosides, nucleotides & nucleic acids 20111201 |
S K-edge XAS and DFT calculations on SAM dependent pyruvate formate-lyase activating enzyme: nature of interaction between the Fe4S4 cluster and SAM and its role in reactivity. | Journal of the American Chemical Society 20111123 |
RAM/Fam103a1 is required for mRNA cap methylation. | Molecular cell 20111118 |
Elucidation of the methyl transfer mechanism catalyzed by chalcone O-methyltransferase: a density functional study. | Journal of computational chemistry 20111115 |
A conserved SREBP-1/phosphatidylcholine feedback circuit regulates lipogenesis in metazoans. | Cell 20111111 |
Synthesis and biochemical evaluation of δ(2)-isoxazoline derivatives as DNA methyltransferase 1 inhibitors. | Journal of medicinal chemistry 20111110 |
Structure-guided design of a methyl donor cofactor that controls a viral histone H3 lysine 27 methyltransferase activity. | Journal of medicinal chemistry 20111110 |
Enzymatic methyl transfer: role of an active site residue in generating active site compaction that correlates with catalytic efficiency. | Journal of the American Chemical Society 20111102 |
Role of PTEN promoter methylation in tamoxifen-resistant breast cancer cells. | Breast cancer research and treatment 20111101 |
Folic acid supplementation during early hepatocarcinogenesis: cellular and molecular effects. | International journal of cancer 20111101 |
Oxidative stress is implicated in arsenic-induced neural tube defects in chick embryos. | International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 20111101 |
Computational investigation of the substrate recognition mechanism of protein D-aspartyl (L-isoaspartyl) O-methyltransferase by docking and molecular dynamics simulation studies and application to interpret size exclusion chromatography data. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101 |
Formulating a fluorogenic assay to evaluate S-adenosyl-L-methionine analogues as protein methyltransferase cofactors. | Molecular bioSystems 20111101 |
S-adenosyl-L-methionine treatment for alcoholic liver disease: a double-blinded, randomized, placebo-controlled trial. | Alcoholism, clinical and experimental research 20111101 |
Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1. | Organic & biomolecular chemistry 20111026 |
In vitro phosphinate methylation by PhpK from Kitasatospora phosalacinea. | Biochemistry 20111025 |
Deletion of betaine-homocysteine S-methyltransferase in mice perturbs choline and 1-carbon metabolism, resulting in fatty liver and hepatocellular carcinomas. | The Journal of biological chemistry 20111021 |
The structure of a tetrahydrofolate-sensing riboswitch reveals two ligand binding sites in a single aptamer. | Structure (London, England : 1993) 20111012 |
Adenosine kinase deficiency disrupts the methionine cycle and causes hypermethioninemia, encephalopathy, and abnormal liver function. | American journal of human genetics 20111007 |
Copper deficiency exacerbates bile duct ligation-induced liver injury and fibrosis in rats. | The Journal of pharmacology and experimental therapeutics 20111001 |
Biochemical and structural insights into the mechanisms of SARS coronavirus RNA ribose 2'-O-methylation by nsp16/nsp10 protein complex. | PLoS pathogens 20111001 |
Natural supplements for mental health. Some complementary and alternative therapies may be worth trying. | The Harvard mental health letter 20111001 |
Structural basis of substrate recognition in human nicotinamide N-methyltransferase. | Biochemistry 20110913 |
Structural basis of substrate methylation and inhibition of SMYD2. | Structure (London, England : 1993) 20110907 |
Complex biotransformations catalyzed by radical S-adenosylmethionine enzymes. | The Journal of biological chemistry 20110902 |
Trichloroethylene induces methylation of the Serca2 promoter in H9c2 cells and embryonic heart. | Cardiovascular toxicology 20110901 |
A maternal dietary pattern characterised by fish and seafood in association with the risk of congenital heart defects in the offspring. | BJOG : an international journal of obstetrics and gynaecology 20110901 |
Vitamin-dependent methionine metabolism and alcoholic liver disease. | Advances in nutrition (Bethesda, Md.) 20110901 |
High bone concentrations of homocysteine are associated with altered bone morphology in humans. | The British journal of nutrition 20110801 |
Arabidopsis cell-free extract, ACE, a new in vitro translation system derived from Arabidopsis callus cultures. | Plant & cell physiology 20110801 |
Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase. | Parasitology 20110801 |
Sulfatases and a radical S-adenosyl-L-methionine (AdoMet) enzyme are key for mucosal foraging and fitness of the prominent human gut symbiont, Bacteroides thetaiotaomicron. | The Journal of biological chemistry 20110722 |
Expanding cofactor repertoire of protein lysine methyltransferase for substrate labeling. | ACS chemical biology 20110715 |
Probing the reaction mechanism of spore photoproduct lyase (SPL) via diastereoselectively labeled dinucleotide SP TpT substrates. | Journal of the American Chemical Society 20110713 |
Differentiating analogous tRNA methyltransferases by fragments of the methyl donor. | RNA (New York, N.Y.) 20110701 |
Inhibition of betaine-homocysteine S-methyltransferase in rats causes hyperhomocysteinemia and reduces liver cystathionine β-synthase activity and methylation capacity. | Nutrition research (New York, N.Y.) 20110701 |
Characterization of NocL involved in thiopeptide nocathiacin I biosynthesis: a [4Fe-4S] cluster and the catalysis of a radical S-adenosylmethionine enzyme. | The Journal of biological chemistry 20110617 |
Characterizing DNA methyltransferases with an ultrasensitive luciferase-linked continuous assay. | Analytical chemistry 20110615 |
Global DNA methylation in the mouse liver is affected by methyl deficiency and arsenic in a sex-dependent manner. | Archives of toxicology 20110601 |
S-adenosylmethionine prevents the up regulation of Toll-like receptor (TLR) signaling caused by chronic ethanol feeding in rats. | Experimental and molecular pathology 20110601 |
A high-throughput absorbance-based assay for methionine produced by methionine aminopeptidase using S-adenosyl-L-methionine synthetase. | Journal of biomolecular screening 20110601 |
Hypoxia induces genomic DNA demethylation through the activation of HIF-1α and transcriptional upregulation of MAT2A in hepatoma cells. | Molecular cancer therapeutics 20110601 |
Auto-methylation of the mouse DNA-(cytosine C5)-methyltransferase Dnmt3a at its active site cysteine residue. | The FEBS journal 20110601 |
Generation of adenosyl radical from S-adenosylmethionine (SAM) in biotin synthase. | Journal of inorganic biochemistry 20110601 |
A domain of the actin binding protein Abp140 is the yeast methyltransferase responsible for 3-methylcytidine modification in the tRNA anti-codon loop. | RNA (New York, N.Y.) 20110601 |
Actin-binding protein ABP140 is a methyltransferase for 3-methylcytidine at position 32 of tRNAs in Saccharomyces cerevisiae. | RNA (New York, N.Y.) 20110601 |
HIV-associated Pneumocystis pneumonia. | Proceedings of the American Thoracic Society 20110601 |
Complementary and alternative medicine for the treatment of major depressive disorder. | Canadian family physician Medecin de famille canadien 20110601 |
Direct evidence for methyl group coordination by carbon-oxygen hydrogen bonds in the lysine methyltransferase SET7/9. | The Journal of biological chemistry 20110527 |
Structural basis for methyl transfer by a radical SAM enzyme. | Science (New York, N.Y.) 20110527 |
Labeling substrates of protein arginine methyltransferase with engineered enzymes and matched S-adenosyl-L-methionine analogues. | Journal of the American Chemical Society 20110525 |
Crystal structures and enzymatic properties of a triamine/agmatine aminopropyltransferase from Thermus thermophilus. | Journal of molecular biology 20110520 |
The effects of dietary supplementation of methionine on genomic stability and p53 gene promoter methylation in rats. | Mutation research 20110518 |
Mechanistic studies of the radical S-adenosyl-L-methionine enzyme DesII: EPR characterization of a radical intermediate generated during its catalyzed dehydrogenation of TDP-D-quinovose. | Journal of the American Chemical Society 20110518 |
Concentrations of unmetabolized folic acid and primary folate forms in plasma after folic acid treatment in older adults. | Metabolism: clinical and experimental 20110501 |
Evidence for the efficacy of complementary and alternative medicines in the management of osteoarthritis: a systematic review. | Rheumatology (Oxford, England) 20110501 |
Effect of S-adenosylmethionine on neointimal formation after balloon injury in obese diabetic rats. | Cardiovascular research 20110501 |
S-adenosylmethionine decreases lipopolysaccharide-induced phosphodiesterase 4B2 and attenuates tumor necrosis factor expression via cAMP/protein kinase A pathway. | The Journal of pharmacology and experimental therapeutics 20110501 |
Ethanol exposure modulates hepatic S-adenosylmethionine and S-adenosylhomocysteine levels in the isolated perfused rat liver through changes in the redox state of the NADH/NAD(+) system. | Biochimica et biophysica acta 20110501 |
The mPlrp2 and mClps genes are involved in the hydrolysis of retinyl esters in the mouse liver. | Journal of lipid research 20110501 |
The role of S-adenosyl methionine in preventing FOLFOX-induced liver toxicity: a retrospective analysis in patients affected by resected colorectal cancer treated with adjuvant FOLFOX regimen. | Expert opinion on drug safety 20110501 |
Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes in Plantago and Arabidopsis. | The Plant cell 20110501 |
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2'-O-methyltransferase nsp10/nsp16 complex. | PLoS pathogens 20110501 |
[Pay more attention to standardizing the diagnosis and treatment of intrahepatic cholestasis of pregnancy]. | Zhonghua fu chan ke za zhi 20110501 |
S-adenosyl-L-methionine induces compaction of nascent peptide chain inside the ribosomal exit tunnel upon translation arrest in the Arabidopsis CGS1 gene. | The Journal of biological chemistry 20110429 |
A radically different mechanism for S-adenosylmethionine-dependent methyltransferases. | Science (New York, N.Y.) 20110429 |
Biochemistry. The two faces of SAM. | Science (New York, N.Y.) 20110429 |
Mechanistic studies on transcriptional coactivator protein arginine methyltransferase 1. | Biochemistry 20110426 |
Characterization of the N-methyltransferase activities of the multifunctional polypeptide cyclosporin synthetase. | Chemistry & biology 20110422 |
Mechanism of Vibrio cholerae autoinducer-1 biosynthesis. | ACS chemical biology 20110415 |
S-Adenosylmethionine regulates connexins sub-types expressed by hepatocytes. | European journal of cell biology 20110401 |
Radicals from S-adenosylmethionine and their application to biosynthesis. | Current opinion in chemical biology 20110401 |
Thymidylate synthase gene polymorphisms and markers of DNA methylation capacity. | Molecular genetics and metabolism 20110401 |
Specific biomarkers for stochastic division patterns and starvation-induced quiescence under limited glucose levels in fission yeast. | The FEBS journal 20110401 |
The C. elegans PRMT-3 possesses a type III protein arginine methyltransferase activity. | Journal of receptor and signal transduction research 20110401 |
The cardiovascular inhibition functions of hydrogen sulfide within the nucleus tractus solitarii are mediated by the activation of KATP channels and glutamate receptors mechanisms. | Die Pharmazie 20110401 |
[Function of luxS gene in sulfurmetabolism of Streptococcus mutans]. | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20110401 |
DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models. | The Journal of nutritional biochemistry 20110301 |
Mthfd1 is a modifier of chemically induced intestinal carcinogenesis. | Carcinogenesis 20110301 |
Impairment of methyl cycle affects mitochondrial methyl availability and glutathione level in Down's syndrome. | Molecular genetics and metabolism 20110301 |
Active site mapping and substrate specificity of bacterial Hen1, a manganese-dependent 3' terminal RNA ribose 2'O-methyltransferase. | RNA (New York, N.Y.) 20110301 |
Radical-mediated enzymatic carbon chain fragmentation-recombination. | Nature chemical biology 20110301 |
Enzymology: Radical break-up, blissful make-up. | Nature chemical biology 20110301 |
Small molecule inhibitors that selectively block dengue virus methyltransferase. | The Journal of biological chemistry 20110225 |
Methyltransferase-directed derivatization of 5-hydroxymethylcytosine in DNA. | Angewandte Chemie (International ed. in English) 20110225 |
Growth and metastases of human lung cancer are inhibited in mouse xenografts by a transition state analogue of 5'-methylthioadenosine phosphorylase. | The Journal of biological chemistry 20110211 |
Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency. | Neurobiology of aging 20110201 |
Determination of cystathionine beta-synthase activity in human plasma by LC-MS/MS: potential use in diagnosis of CBS deficiency. | Journal of inherited metabolic disease 20110201 |
Functional and structural evaluation of cysteine residues in the human arsenic (+3 oxidation state) methyltransferase (hAS3MT). | Biochimie 20110201 |
Radical SAM activation of the B12-independent glycerol dehydratase results in formation of 5'-deoxy-5'-(methylthio)adenosine and not 5'-deoxyadenosine. | Biochemistry 20110201 |
Folic acid effects on s-adenosylmethionine, s-adenosylhomocysteine, and DNA methylation in patients with intermediate hyperhomocysteinemia. | Journal of the American College of Nutrition 20110201 |
A chemical method for labeling lysine methyltransferase substrates. | Chembiochem : a European journal of chemical biology 20110124 |
QM/MM free energy simulations of salicylic acid methyltransferase: effects of stabilization of TS-like structures on substrate specificity. | The journal of physical chemistry. B 20110120 |
Pharmacological activation and genetic manipulation of cystathionine beta-synthase alter circulating levels of homocysteine and hydrogen sulfide in mice. | European journal of pharmacology 20110110 |
Possible regulation of trehalose metabolism by methylation in Saccharomyces cerevisiae. | Journal of cellular physiology 20110101 |
Specificity shifts in the rRNA and tRNA nucleotide targets of archaeal and bacterial m5U methyltransferases. | RNA (New York, N.Y.) 20110101 |
Nitric oxide synthase inhibitors and cerebral vasospasm. | Acta neurochirurgica. Supplement 20110101 |
Phosphoprotein affinity purification identifies proteins involved in S-adenosyl-L-methionine-induced enhancement of antibiotic production in Streptomyces coelicolor. | The Journal of antibiotics 20110101 |
Methylthioadenosine/S-adenosylhomocysteine nucleosidase, a critical enzyme for bacterial metabolism. | Molecular microbiology 20110101 |
Functional analysis of an acid adaptive DNA adenine methyltransferase from Helicobacter pylori 26695. | PloS one 20110101 |
[Treatment of obstetric cholestasis with polyunsaturated phosphatidylcholine and ursodeoxycholic acid]. | Ginekologia polska 20110101 |
[Comparative study of remaxol and ademethionine effects on reparative regeneration processes in the liver subjected to surgical intervention]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
HC-Pro silencing suppressor significantly alters the gene expression profile in tobacco leaves and flowers. | BMC plant biology 20110101 |
[Diagnosis and treatment of intrahepatic cholestasis in chronic diseases of the liver]. | Terapevticheskii arkhiv 20110101 |
Identification and characterization of the Chlamydia trachomatis L2 S-adenosylmethionine transporter. | mBio 20110101 |
[Intrahepatic cholestasis in chronic liver diseases]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20110101 |
S-adenosyl-L-methionine activates actinorhodin biosynthesis by increasing autophosphorylation of the Ser/Thr protein kinase AfsK in Streptomyces coelicolor A3(2). | Bioscience, biotechnology, and biochemistry 20110101 |
Modeling a new water channel that allows SET9 to dimethylate p53. | PloS one 20110101 |
Prospective randomized clinical trial assessing the efficacy of Denamarin for prevention of CCNU-induced hepatopathy in tumor-bearing dogs. | Journal of veterinary internal medicine 20110101 |
Individual variations in inorganic arsenic metabolism associated with AS3MT genetic polymorphisms. | International journal of molecular sciences 20110101 |
Amelioration of D-galactosamine-induced acute liver injury in rats by dietary supplementation with betaine derived from sugar beet molasses. | Bioscience, biotechnology, and biochemistry 20110101 |
Genome mining for radical SAM protein determinants reveals multiple sactibiotic-like gene clusters. | PloS one 20110101 |
[Comparative study of hepatoprotective action of remaxol, reamberin and ademethionine in liver injury induced by antituberculosis drugs (experimental study)]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20110101 |
Properties and crystal structure of methylenetetrahydrofolate reductase from Thermus thermophilus HB8. | PloS one 20110101 |
Structural mechanism of S-adenosyl methionine binding to catechol O-methyltransferase. | PloS one 20110101 |
Recognition of S-adenosylmethionine by riboswitches. | Wiley interdisciplinary reviews. RNA 20110101 |
Analysis of RNA binding by the dengue virus NS5 RNA capping enzyme. | PloS one 20110101 |
Comparative effects of triflusal, S-adenosylmethionine, and dextromethorphan over intestinal ischemia/reperfusion injury. | TheScientificWorldJournal 20110101 |
A conformational switch in the active site of BT_2972, a methyltransferase from an antibiotic resistant pathogen B. thetaiotaomicron. | PloS one 20110101 |
[Induction of endogenous s-adenosyl-l-methionine in hepatocytes during pharmacological correction of experimental acute toxic and chronic drug-induced liver injury]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
Cloning and functional analysis of the GSH1/MET1 gene complementing cysteine and glutathione auxotrophy of the methylotrophic yeast Hansenula polymorpha. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101 |
Clinical depression: an evidence-based integrative complementary medicine treatment model. | Alternative therapies in health and medicine 20110101 |
[S-adenosyl L-methionine in CNS diseases]. | Psychiatria polska 20110101 |
Structure-based and ligand-based virtual screening of novel methyltransferase inhibitors of the dengue virus. | BMC bioinformatics 20110101 |
SAM recognition and conformational switching mechanism in the Bacillus subtilis yitJ S box/SAM-I riboswitch. | Journal of molecular biology 20101217 |
Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica. | The Journal of biological chemistry 20101210 |
High-level expression and reconstitution of active Cfr, a radical-SAM rRNA methyltransferase that confers resistance to ribosome-acting antibiotics. | Protein expression and purification 20101201 |
S-adenosylmethionine decreases the peak blood alcohol levels 3 h after an acute bolus of ethanol by inducing alcohol metabolizing enzymes in the liver. | Experimental and molecular pathology 20101201 |
Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9. | Bioorganic & medicinal chemistry 20101201 |
O-carboxyl- and N-methyltransferases active on plant aquaporins. | Plant & cell physiology 20101201 |
Discrepancy in response and remission rates for SAMe-treated patients in a double-blind, randomized clinical trial. | The American journal of psychiatry 20101201 |
Biochemical research elucidating metabolic pathways in Pneumocystis. | Parasite (Paris, France) 20101201 |
Biotin synthase exhibits burst kinetics and multiple turnovers in the absence of inhibition by products and product-related biomolecules. | Biochemistry 20101123 |
Some more comments on 'folate deficiency in chronic pancreatitis'. | JOP : Journal of the pancreas 20101109 |
A 'radical dance' in thiamin biosynthesis: mechanistic analysis of the bacterial hydroxymethylpyrimidine phosphate synthase. | Angewandte Chemie (International ed. in English) 20101108 |
Förster resonance energy transfer measurements of cofactor-dependent effects on protein arginine N-methyltransferase homodimerization. | Protein science : a publication of the Protein Society 20101101 |
Mechanisms and cell signaling in alcoholic liver disease. | Biological chemistry 20101101 |
Characterization and structure of DhpI, a phosphonate O-methyltransferase involved in dehydrophos biosynthesis. | Proceedings of the National Academy of Sciences of the United States of America 20101012 |
Interaction of PqqE and PqqD in the pyrroloquinoline quinone (PQQ) biosynthetic pathway links PqqD to the radical SAM superfamily. | Chemical communications (Cambridge, England) 20101007 |
Current understanding of the factors regulating methionine content in vegetative tissues of higher plants. | Amino acids 20101001 |
SAM domain-dependent activity of PfTKL3, an essential tyrosine kinase-like kinase of the human malaria parasite Plasmodium falciparum. | Cellular and molecular life sciences : CMLS 20101001 |
New insights into the mechanism of arsenite methylation with the recombinant human arsenic (+3) methyltransferase (hAS3MT). | Biochimie 20101001 |
Analysis of trace degradation products (decarboxylated diastereoisomers) of S-adenosylmethionine by electrophoresis in capillaries with cationic coatings (N-methylpolyvinylpyridinium or divalent barium). | Electrophoresis 20101001 |
S-adenosyl-L-methionine regulation of the cardiac ryanodine receptor involves multiple mechanisms. | Biochemistry 20100907 |
Characterization of a Vitis vinifera cv. Cabernet Sauvignon 3',5'-O-methyltransferase showing strong preference for anthocyanins and glycosylated flavonols. | Phytochemistry 20100901 |
Ethylene and nitric oxide involvement in the up-regulation of key genes related to iron acquisition and homeostasis in Arabidopsis. | Journal of experimental botany 20100901 |
Using complementary and alternative medicines for depression. | The Journal of clinical psychiatry 20100901 |
Temporal study of acetaminophen (APAP) and S-adenosyl-L-methionine (SAMe) effects on subcellular hepatic SAMe levels and methionine adenosyltransferase (MAT) expression and activity. | Toxicology and applied pharmacology 20100815 |
Atomistic details of the ligand discrimination mechanism of S(MK)/SAM-III riboswitch. | The journal of physical chemistry. B 20100805 |
Regulation of homocysteine metabolism and methylation in human and mouse tissues. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100801 |
Herbivore-induced SABATH methyltransferases of maize that methylate anthranilic acid using s-adenosyl-L-methionine. | Plant physiology 20100801 |
Neural tube defects induced by folate deficiency in mutant curly tail (Grhl3) embryos are associated with alteration in folate one-carbon metabolism but are unlikely to result from diminished methylation. | Birth defects research. Part A, Clinical and molecular teratology 20100801 |
S-adenosyl methionine (SAMe) augmentation of serotonin reuptake inhibitors for antidepressant nonresponders with major depressive disorder: a double-blind, randomized clinical trial. | The American journal of psychiatry 20100801 |
Efficacy and safety of intravenous stronger neo-minophagen C and S-adenosyl-L-methionine in treatment of pregnant woman with chronic hepatitis B: a pilot study. | Medical science monitor : international medical journal of experimental and clinical research 20100801 |
S-adenosyl methionine (SAMe) augmentation in major depressive disorder. | The American journal of psychiatry 20100801 |
Accessing protein methyltransferase and demethylase enzymology using microfluidic capillary electrophoresis. | Chemistry & biology 20100730 |
Molecular characterization of O-methyltransferases involved in isoquinoline alkaloid biosynthesis in Coptis japonica. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20100721 |
Molecular architecture of a C-3'-methyltransferase involved in the biosynthesis of D-tetronitrose. | Biochemistry 20100720 |
[FeFe]-hydrogenase maturation: HydG-catalyzed synthesis of carbon monoxide. | Journal of the American Chemical Society 20100714 |
Homology modeling and molecular dynamics simulations of HgiDII methyltransferase in complex with DNA and S-adenosyl-methionine: catalytic mechanism and interactions with DNA. | Journal of molecular modeling 20100701 |
Fatty liver and fibrosis in glycine N-methyltransferase knockout mice is prevented by nicotinamide. | Hepatology (Baltimore, Md.) 20100701 |
Dietary intake of S-(alpha-carboxybutyl)-DL-homocysteine induces hyperhomocysteinemia in rats. | Nutrition research (New York, N.Y.) 20100701 |
High affinity S-Adenosylmethionine plasma membrane transporter of Leishmania is a member of the folate biopterin transporter (FBT) family. | The Journal of biological chemistry 20100625 |
Higher catalytic efficiency of N-7-methylation is responsible for processive N-7 and 2'-O methyltransferase activity in dengue virus. | Virology 20100620 |
Repair of isoaspartate formation modulates the interaction of deamidated 4E-BP2 with mTORC1 in brain. | The Journal of biological chemistry 20100618 |
Diphthamide biosynthesis requires an organic radical generated by an iron-sulphur enzyme. | Nature 20100617 |
An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases. | Analytical biochemistry 20100615 |
Specific contribution of methionine and choline in nutritional nonalcoholic steatohepatitis: impact on mitochondrial S-adenosyl-L-methionine and glutathione. | The Journal of biological chemistry 20100611 |
Homocysteine-lowering vitamins do not lower plasma S-adenosylhomocysteine in older people with elevated homocysteine concentrations. | The British journal of nutrition 20100601 |
In vivo proton MR spectroscopy findings specific for adenylosuccinate lyase deficiency. | NMR in biomedicine 20100601 |
Evidence for the efficacy of complementary and alternative medicines in the management of fibromyalgia: a systematic review. | Rheumatology (Oxford, England) 20100601 |
SAMe prevents the up regulation of toll-like receptor signaling in Mallory-Denk body forming hepatocytes. | Experimental and molecular pathology 20100601 |
SAMe prevents the induction of the immunoproteasome and preserves the 26S proteasome in the DDC-induced MDB mouse model. | Experimental and molecular pathology 20100601 |
The cyclic pattern of blood alcohol levels during continuous ethanol feeding in rats: the effect of feeding S-adenosylmethionine. | Experimental and molecular pathology 20100601 |
Complementary and alternative medicine for major depressive disorder: a meta-analysis of patient characteristics, placebo-response rates, and treatment outcomes relative to standard antidepressants. | The Journal of clinical psychiatry 20100601 |
S-Adenosyl-L-methionine ameliorates TNFalpha-induced insulin resistance in 3T3-L1 adipocytes. | Experimental & molecular medicine 20100531 |
The major product ion of S-adenosyl-L-methionine arises from a neighbouring group reaction. | Rapid communications in mass spectrometry : RCM 20100530 |
A consensus mechanism for Radical SAM-dependent dehydrogenation? BtrN contains two [4Fe-4S] clusters. | Biochemistry 20100511 |
Methotrexate-induced myelopathy responsive to substitution of multiple folate metabolites. | Journal of neuro-oncology 20100501 |
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors. | Toxicological sciences : an official journal of the Society of Toxicology 20100501 |
Analysis of the liver mitochondrial proteome in response to ethanol and S-adenosylmethionine treatments: novel molecular targets of disease and hepatoprotection. | American journal of physiology. Gastrointestinal and liver physiology 20100501 |
Formation of spray-dried powder of S-adenosyl-L-methionine. | Biotechnology journal 20100501 |
Oxidative stress and the pathogenesis of cholestasis. | Seminars in liver disease 20100501 |
Hepatoprotective effects of antioxidants in chronic hepatitis C. | World journal of gastroenterology 20100421 |
Binding of MetJ repressor to specific and nonspecific DNA and effect of S-adenosylmethionine on these interactions. | Biochemistry 20100420 |
Blood folate status and expression of proteins involved in immune function, inflammation, and coagulation: biochemical and proteomic changes in the plasma of humans in response to long-term synthetic folic acid supplementation. | Journal of proteome research 20100405 |
Evaluation of phospholipid and liposomal S-adenosyl methionine for the treatment of liver injury in a murine model. | Journal of pharmaceutical sciences 20100401 |
Induction of avian musculoaponeurotic fibrosarcoma proteins by toxic bile acid inhibits expression of glutathione synthetic enzymes and contributes to cholestatic liver injury in mice. | Hepatology (Baltimore, Md.) 20100401 |
S-Adenosylmethionine (SAM) and antibiotic biosynthesis: effect of external addition of SAM and of overexpression of SAM biosynthesis genes on novobiocin production in Streptomyces. | Archives of microbiology 20100401 |
Anaerobic sulfatase-maturating enzyme--a mechanistic link with glycyl radical-activating enzymes? | The FEBS journal 20100401 |
Toward the development of potent and selective bisubstrate inhibitors of protein arginine methyltransferases. | Bioorganic & medicinal chemistry letters 20100401 |
Folate, DNA damage and the aging brain. | Mechanisms of ageing and development 20100401 |
[Efficacy and safety of ademetionine for treatment of drug-induced liver disease in children]. | Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology 20100401 |
Binding of adenosine-based ligands to the MjDim1 rRNA methyltransferase: implications for reaction mechanism and drug design. | Biochemistry 20100330 |
RlmN and Cfr are radical SAM enzymes involved in methylation of ribosomal RNA. | Journal of the American Chemical Society 20100324 |
Enzyme-catalyzed transfer of a ketone group from an S-adenosylmethionine analogue: a tool for the functional analysis of methyltransferases. | Journal of the American Chemical Society 20100324 |
Adenosyl radical: reagent and catalyst in enzyme reactions. | Chembiochem : a European journal of chemical biology 20100322 |
Hepatoprotective effects of S-adenosyl-L-methionine against alcohol- and cytochrome P450 2E1-induced liver injury. | World journal of gastroenterology 20100321 |
The antiviral protein viperin is a radical SAM enzyme. | FEBS letters 20100319 |
Simultaneous analysis of catechol-O-methyl transferase activity, S-adenosylhomocysteine and adenosine. | Biomedical chromatography : BMC 20100301 |
DNA methylation regulates adenosine A(2A) receptor cell surface expression levels. | Journal of neurochemistry 20100301 |
Changes in the expression of methionine adenosyltransferase genes and S-adenosylmethionine homeostasis during hepatic stellate cell activation. | Hepatology (Baltimore, Md.) 20100301 |
Idiosyncratically tuned switching behavior of riboswitch aptamer domains revealed by comparative small-angle X-ray scattering analysis. | RNA (New York, N.Y.) 20100301 |
A vitamin/nutriceutical formulation improves memory and cognitive performance in community-dwelling adults without dementia. | The journal of nutrition, health & aging 20100301 |
[The role of DNA methylation in the pathogenesis of adult idiopathic thrombocytopenic purpura]. | Zhonghua nei ke za zhi 20100301 |
Discrimination between closely related cellular metabolites by the SAM-I riboswitch. | Journal of molecular biology 20100226 |
Binding of S-methyl-5'-thioadenosine and S-adenosyl-L-methionine to protein MJ0100 triggers an open-to-closed conformational change in its CBS motif pair. | Journal of molecular biology 20100226 |
Stoichiometry of the redox neutral deamination and oxidative dehydrogenation reactions catalyzed by the radical SAM enzyme DesII. | Journal of the American Chemical Society 20100224 |
[FeFe]-hydrogenase cyanide ligands derived from S-adenosylmethionine-dependent cleavage of tyrosine. | Angewandte Chemie (International ed. in English) 20100222 |
Catalytic activity of the anaerobic tyrosine lyase required for thiamine biosynthesis in Escherichia coli. | The Journal of biological chemistry 20100219 |
Post-translational modification of ribosomal proteins: structural and functional characterization of RimO from Thermotoga maritima, a radical S-adenosylmethionine methylthiotransferase. | The Journal of biological chemistry 20100219 |
Enhanced one-carbon flux towards DNA methylation: Effect of dietary methyl supplements against gamma-radiation-induced epigenetic modifications. | Chemico-biological interactions 20100212 |
Bacterial Hen1 is a 3' terminal RNA ribose 2'-O-methyltransferase component of a bacterial RNA repair cassette. | RNA (New York, N.Y.) 20100201 |
Effects of salvianolic acids on oxidative stress and hepatic fibrosis in rats. | Toxicology and applied pharmacology 20100115 |
Impaired transmethylation potential in Parkinson's disease patients treated with L-Dopa. | Neuroscience letters 20100114 |
Impaired methylation as a novel mechanism for proteasome suppression in liver cells. | Biochemical and biophysical research communications 20100108 |
Sources of S-adenosyl-L-homocysteine background in measuring protein arginine N-methyltransferase activity using tandem mass spectrometry. | Analytical biochemistry 20100101 |
The logic of the hepatic methionine metabolic cycle. | Biochimica et biophysica acta 20100101 |
Automatic policing of biochemical annotations using genomic correlations. | Nature chemical biology 20100101 |
Methionine-deficient diet induces post-transcriptional downregulation of cystathionine β-synthase. | Nutrition (Burbank, Los Angeles County, Calif.) 20100101 |
Homocysteine metabolism and its relation to health and disease. | BioFactors (Oxford, England) 20100101 |
S-adenosylmethionine prevents oxidative stress and modulates glutathione metabolism in TgCRND8 mice fed a B-vitamin deficient diet. | Journal of Alzheimer's disease : JAD 20100101 |
Chromatin remodeling regulation by small molecules and metabolites. | Biochimica et biophysica acta 20100101 |
S-adenosylmethionine is decreased in the cerebrospinal fluid of patients with Alzheimer's disease. | Neuro-degenerative diseases 20100101 |
Adult Polyglucosan Body Disease (APBD): Anaplerotic diet therapy (Triheptanoin) and demonstration of defective methylation pathways. | Molecular genetics and metabolism 20100101 |
Determination of S-adenosyl-l-methionine in fruits by capillary electrophoresis. | Phytochemical analysis : PCA 20100101 |
[Acute toxic hepatitis at mushroom poisoning of the young child]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20100101 |
Does methionine restriction cause hyperhomocysteinemia? | Nutrition (Burbank, Los Angeles County, Calif.) 20100101 |
S-adenosyl-methionine and betaine improve early virological response in chronic hepatitis C patients with previous nonresponse. | PloS one 20100101 |
Catechol-O-methyltransferase enzyme: cofactor S-adenosyl-L-methionine and related mechanisms. | International review of neurobiology 20100101 |
Metabolic and evolutionary insights into the closely-related species Streptomyces coelicolor and Streptomyces lividans deduced from high-resolution comparative genomic hybridization. | BMC genomics 20100101 |
An Ash2L/RbBP5 heterodimer stimulates the MLL1 methyltransferase activity through coordinated substrate interactions with the MLL1 SET domain. | PloS one 20100101 |
S-adenosylmethionine inhibits the growth of cancer cells by reversing the hypomethylation status of c-myc and H-ras in human gastric cancer and colon cancer. | International journal of biological sciences 20100101 |
Biochemical control of CARM1 enzymatic activity by phosphorylation. | The Journal of biological chemistry 20091225 |
An investigation of the catalytic mechanism of S-adenosylmethionine synthetase by QM/MM calculations. | Archives of biochemistry and biophysics 20091201 |
Update and critique of natural remedies as antidepressant treatments. | Obstetrics and gynecology clinics of North America 20091201 |
Comparative clinical trial of S-adenosylmethionine versus nabumetone for the treatment of knee osteoarthritis: an 8-week, multicenter, randomized, double-blind, double-dummy, Phase IV study in Korean patients. | Clinical therapeutics 20091201 |
An enzyme-coupled continuous spectrophotometric assay for magnesium protoporphyrin IX methyltransferases. | Analytical biochemistry 20091115 |
Simultaneous quantification of S-adenosyl methionine and S-adenosyl homocysteine in human plasma by stable-isotope dilution ultra performance liquid chromatography tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091115 |
Homocysteine supplementation attenuates the unfolded protein response in a murine nutritional model of steatohepatitis. | The Journal of biological chemistry 20091113 |
DNA hypomethylation induced by tributyltin, triphenyltin, and a mixture of these in Sebastiscus marmoratus liver. | Aquatic toxicology (Amsterdam, Netherlands) 20091108 |
Can adenosine substitute for SAM-e as an adjunct in the treatment of depression? | Medical hypotheses 20091101 |
A combinatorial interplay among the 1-aminocyclopropane-1-carboxylate isoforms regulates ethylene biosynthesis in Arabidopsis thaliana. | Genetics 20091101 |
Analysis of S-adenosylmethionine and related sulfur metabolites in bacterial isolates of Pseudomonas aeruginosa (BAA-47) by liquid chromatography/electrospray ionization coupled to a hybrid linear quadrupole ion trap and Fourier transform ion cyclotron resonance mass spectrometry. | Rapid communications in mass spectrometry : RCM 20091101 |
S-adenosyl-L-methionine restores photoreceptor function following acute retinal ischemia. | Visual neuroscience 20091101 |
Characterization of RimO, a new member of the methylthiotransferase subclass of the radical SAM superfamily. | Biochemistry 20091027 |
Pyrroloquinoline quinone biogenesis: demonstration that PqqE from Klebsiella pneumoniae is a radical S-adenosyl-L-methionine enzyme. | Biochemistry 20091027 |
Complete reconstitution of a highly reducing iterative polyketide synthase. | Science (New York, N.Y.) 20091023 |
Evolution of putrescine N-methyltransferase from spermidine synthase demanded alterations in substrate binding. | FEBS letters 20091020 |
Alpha-lipoic acid induces elevated S-adenosylhomocysteine and depletes S-adenosylmethionine. | Free radical biology & medicine 20091015 |
Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. | Biochemistry 20091013 |
Discovery of novel types of inhibitors of S-adenosylmethionine synthesis by virtual screening. | Journal of medicinal chemistry 20091008 |
Characterization and mechanistic studies of DesII: a radical S-adenosyl-L-methionine enzyme involved in the biosynthesis of TDP-D-desosamine. | Journal of the American Chemical Society 20091007 |
A lipid profile typifies the Beijing strains of Mycobacterium tuberculosis: identification of a mutation responsible for a modification of the structures of phthiocerol dimycocerosates and phenolic glycolipids. | The Journal of biological chemistry 20091002 |
Effect of 40% restriction of dietary amino acids (except methionine) on mitochondrial oxidative stress and biogenesis, AIF and SIRT1 in rat liver. | Biogerontology 20091001 |
S-adenosylmethionine and S-adenosylhomocysteine levels in the aging brain of APP/PS1 Alzheimer mice. | Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology 20091001 |
A mediator of Rho-dependent invasion moonlights as a methionine salvage enzyme. | Molecular & cellular proteomics : MCP 20091001 |
Fibrates may cause an abnormal urinary betaine loss which is associated with elevations in plasma homocysteine. | Cardiovascular drugs and therapy 20091001 |
Canadian Network for Mood and Anxiety Treatments (CANMAT) Clinical guidelines for the management of major depressive disorder in adults. V. Complementary and alternative medicine treatments. | Journal of affective disorders 20091001 |
Methylation status and neurodegenerative markers in Parkinson disease. | Clinical chemistry 20091001 |
Mutagenesis of the enolase-phosphatase gene in Xanthomonas oryzae pv. oryzae affects growth on methylthioadenosine and in vivo S-adenosylmethionine pools. | Archives of microbiology 20091001 |
The Pseudomonas aeruginosa nirE gene encodes the S-adenosyl-L-methionine-dependent uroporphyrinogen III methyltransferase required for heme d(1) biosynthesis. | The FEBS journal 20091001 |
Experimental hyperhomocysteinaemia: differences in tissue metabolites between homocystine and methionine feeding in a rat model. | Acta physiologica (Oxford, England) 20090901 |
Polyamine biosynthesis impacts cellular folate requirements necessary to maintain S-adenosylmethionine and nucleotide pools. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090901 |
Marine-derived metabolites of S-adenosylmethionine as templates for new anti-infectives. | Marine drugs 20090901 |
Glycine N-methyltransferase and regulation of S-adenosylmethionine levels. | The Journal of biological chemistry 20090821 |
Dietary deficiency increases presenilin expression, gamma-secretase activity, and Abeta levels: potentiation by ApoE genotype and alleviation by S-adenosyl methionine. | Journal of neurochemistry 20090801 |
Impaired liver regeneration in mice lacking glycine N-methyltransferase. | Hepatology (Baltimore, Md.) 20090801 |
Studies of acetaminophen and metabolites in urine and their correlations with toxicity using metabolomics. | Drug metabolism letters 20090801 |
Aquifex aeolicus tRNA (N2,N2-guanine)-dimethyltransferase (Trm1) catalyzes transfer of methyl groups not only to guanine 26 but also to guanine 27 in tRNA. | The Journal of biological chemistry 20090731 |
Biosynthesis of the salinosporamide A polyketide synthase substrate chloroethylmalonyl-coenzyme A from S-adenosyl-L-methionine. | Proceedings of the National Academy of Sciences of the United States of America 20090728 |
S-adenosyl-N-decyl-aminoethyl, a potent bisubstrate inhibitor of mycobacterium tuberculosis mycolic acid methyltransferases. | The Journal of biological chemistry 20090717 |
New S-adenosyl-L-methionine analogues: synthesis and reactivity studies. | Organic letters 20090716 |
Metabolic defects provide a spark for the epigenetic switch in cancer. | Free radical biology & medicine 20090715 |
Determination of S-Adenosylmethionine and S-Adenosylhomocysteine by LC-MS/MS and evaluation of their stability in mice tissues. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715 |
S-Adenosylmethionine and methylthioadenosine inhibit cellular FLICE inhibitory protein expression and induce apoptosis in colon cancer cells. | Molecular pharmacology 20090701 |
Mitochondrial S-adenosyl-L-methionine transport is insensitive to alcohol-mediated changes in membrane dynamics. | Alcoholism, clinical and experimental research 20090701 |
SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers. | Plant molecular biology 20090701 |
Optimization of L: -methionine feeding strategy for improving S-adenosyl-L: -methionine production by methionine adenosyltransferase overexpressed Pichia pastoris. | Applied microbiology and biotechnology 20090701 |
Mechanistic investigations of anaerobic sulfatase-maturating enzyme: direct Cbeta H-atom abstraction catalyzed by a radical AdoMet enzyme. | Journal of the American Chemical Society 20090624 |
Structure of the thiostrepton resistance methyltransferase.S-adenosyl-L-methionine complex and its interaction with ribosomal RNA. | The Journal of biological chemistry 20090619 |
S-adenosylmethionine regulates thiopurine methyltransferase activity and decreases 6-mercaptopurine cytotoxicity in MOLT lymphoblasts. | Biochemical pharmacology 20090615 |
Ethanol-induced liver injury and changes in sulfur amino acid metabolomics in glutathione peroxidase and catalase double knockout mice. | Journal of hepatology 20090601 |
Dysregulation of glutathione synthesis during cholestasis in mice: molecular mechanisms and therapeutic implications. | Hepatology (Baltimore, Md.) 20090601 |
Effects of selenium on the structure and function of recombinant human S-adenosyl-L-methionine dependent arsenic (+3 oxidation state) methyltransferase in E. coli. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20090501 |
Alcoholic liver disease and methionine metabolism. | Seminars in liver disease 20090501 |
Dietary supplement S-adenosyl-L-methionine (AdoMet) effects on plasma homocysteine levels in healthy human subjects: a double-blind, placebo-controlled, randomized clinical trial. | Journal of alternative and complementary medicine (New York, N.Y.) 20090501 |
Therapeutic use of cytoprotective agents in canine and feline hepatobiliary disease. | The Veterinary clinics of North America. Small animal practice 20090501 |
Structure and function of the glycopeptide N-methyltransferase MtfA, a tool for the biosynthesis of modified glycopeptide antibiotics. | Chemistry & biology 20090424 |
Functional characterization and modulation of the DNA cleavage efficiency of type III restriction endonuclease EcoP15I in its interaction with two sites in the DNA target. | Journal of molecular biology 20090417 |
Homocysteine and lipids: S-adenosyl methionine as a key intermediate. | FEBS letters 20090417 |
Product inhibition in the radical S-adenosylmethionine family. | FEBS letters 20090417 |
Experimental folate and vitamin B12 deficiency does not alter bone quality in rats. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090401 |
Betaine prevents Mallory-Denk body formation in drug-primed mice by epigenetic mechanisms. | Experimental and molecular pathology 20090401 |
Alternative treatments in pediatric bipolar disorder. | Child and adolescent psychiatric clinics of North America 20090401 |
Structure analysis of the conserved methyltransferase domain of human trimethylguanosine synthase TGS1. | Acta crystallographica. Section D, Biological crystallography 20090401 |
Magnolia officinalis reverses alcoholic fatty liver by inhibiting the maturation of sterol regulatory element-binding protein-1c. | Journal of pharmacological sciences 20090401 |
Hepatic cystathionine beta-synthase activity does not increase in response to methionine supplementation in rats fed a low casein diet: association with plasma homocysteine concentrations. | Journal of nutritional science and vitaminology 20090401 |
[Optimization of high-cell-density fermentation process for S-adenosyl-L-methionine production]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20090401 |
Oxidative stress-induced regulation of the methionine metabolic pathway in human lung epithelial-like (A549) cells. | Mutation research 20090331 |
Protein residues that control the reaction trajectory in S-adenosylmethionine radical enzymes: mutagenesis of asparagine 153 and aspartate 155 in Escherichia coli biotin synthase. | Biochemistry 20090324 |
New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues of S-adenosylmethionine. | Journal of medicinal chemistry 20090312 |
Inhibition of methionine adenosyltransferase II induces FasL expression, Fas-DISC formation and caspase-8-dependent apoptotic death in T leukemic cells. | Cell research 20090301 |
Hyperhomocysteinemia induces a tissue specific accumulation of homocysteine in bone by collagen binding and adversely affects bone. | Bone 20090301 |
Effects of insulin and glucose on cellular metabolic fluxes in homocysteine transsulfuration, remethylation, S-adenosylmethionine synthesis, and global deoxyribonucleic acid methylation. | The Journal of clinical endocrinology and metabolism 20090301 |
Major depressive disorder and nutritional medicine: a review of monotherapies and adjuvant treatments. | Nutrition reviews 20090301 |
Identification of stable S-adenosylmethionine (SAM) analogues derivatised with bioorthogonal tags: effect of ligands on the affinity of the E. coli methionine repressor, MetJ, for its operator DNA. | Organic & biomolecular chemistry 20090221 |
An intact SAM-dependent methyltransferase fold is encoded by the human endothelin-converting enzyme-2 gene. | Proteins 20090215 |
Evaluations of the trans-sulfuration pathway in multiple liver toxicity studies. | Toxicology and applied pharmacology 20090215 |
Taurine supplementation improves the utilization of sulfur-containing amino acids in rats continually administrated alcohol. | The Journal of nutritional biochemistry 20090201 |
Liposome dependent delivery of S-adenosyl methionine to cells by liposomes: a potential treatment for liver disease. | Journal of pharmaceutical sciences 20090201 |
Structure-function relationships in methionine adenosyltransferases. | Cellular and molecular life sciences : CMLS 20090201 |
In utero ethanol exposure impairs defenses against experimental group B streptococcus in the term Guinea pig lung. | Alcoholism, clinical and experimental research 20090201 |
Anaerobic functionalization of unactivated C-H bonds. | Current opinion in chemical biology 20090201 |
Pharmacokinetic properties of S-adenosylmethionine after oral and intravenous administration of its tosylate disulfate salt: a multiple-dose, open-label, parallel-group study in healthy Chinese volunteers. | Clinical therapeutics 20090201 |
Reaction of AdoMet with ThiC generates a backbone free radical. | Biochemistry 20090120 |
Mthfd1 is an essential gene in mice and alters biomarkers of impaired one-carbon metabolism. | The Journal of biological chemistry 20090116 |
Recognition of RNA cap in the Wesselsbron virus NS5 methyltransferase domain: implications for RNA-capping mechanisms in Flavivirus. | Journal of molecular biology 20090109 |
Complementary and alternative medicine for perinatal depression. | Journal of affective disorders 20090101 |
Improvement of aggressive behavior and quality of life impairment following S-adenosyl-methionine (SAM-e) augmentation in schizophrenia. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20090101 |
S-adenosyl-L-methionine co-administration prevents the ethanol-elicited dissociation of hepatic mitochondrial ribosomes in male rats. | Alcoholism, clinical and experimental research 20090101 |
Resveratrol supplementation worsen the dysregulation of genes involved in hepatic lipid homeostasis observed in hyperhomocysteinemic mice. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20090101 |
Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism. | The American journal of clinical nutrition 20090101 |
The polyamine and histamine metabolic interplay in cancer and chronic inflammation. | Current opinion in clinical nutrition and metabolic care 20090101 |
S-Adenosyl-L-methionine increases serum BUN and creatinine in cisplatin-treated mice. | Archives of medical research 20090101 |
Dietary selenium (Se) and copper (Cu) interact to affect homocysteine metabolism in rats. | Biological trace element research 20090101 |
Possible role of S-adenosylmethionine, S-adenosylhomocysteine, and polyunsaturated fatty acids in predementia syndromes and Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20090101 |
Application of fluorescent measurements for characterization of riboswitch-ligand interactions. | Methods in molecular biology (Clifton, N.J.) 20090101 |
Dietary deficiency in folate and vitamin E under conditions of oxidative stress increases phospho-tau levels: potentiation by ApoE4 and alleviation by S-adenosylmethionine. | Journal of Alzheimer's disease : JAD 20090101 |
Polyunsaturated fatty acid and S-adenosylmethionine supplementation in predementia syndromes and Alzheimer's disease: a review. | TheScientificWorldJournal 20090101 |
Boron deprivation decreases liver S-adenosylmethionine and spermidine and increases plasma homocysteine and cysteine in rats. | Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20090101 |
Homocysteine metabolism and cerebrospinal fluid markers for Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20090101 |
Tyrosine, cysteine, and S-adenosyl methionine stimulate in vitro [FeFe] hydrogenase activation. | PloS one 20090101 |
Periconceptional maternal folic acid use of 400 microg per day is related to increased methylation of the IGF2 gene in the very young child. | PloS one 20090101 |
[Lipid peroxidation and antioxidant system status in patients with acute myeloblast leukemia and toxic damage of the liver]. | Likars'ka sprava 20090101 |
A new 1'-methylenedisulfide deoxyribose that forms an efficient cross-link to DNA cytosine-5 methyltransferase (DNMT). | Journal of the American Chemical Society 20081231 |
Excessive S-adenosyl-L-methionine-dependent methylation increases levels of methanol, formaldehyde and formic acid in rat brain striatal homogenates: possible role in S-adenosyl-L-methionine-induced Parkinson's disease-like disorders. | Life sciences 20081219 |
Folate and S-adenosylmethionine modulate synaptic activity in cultured cortical neurons: acute differential impact on normal and apolipoprotein-deficient mice. | Physical biology 20081219 |
Active cystathionine beta-synthase can be expressed in heme-free systems in the presence of metal-substituted porphyrins or a chemical chaperone. | The Journal of biological chemistry 20081212 |
Spectroscopic study of the cobalamin-dependent methionine synthase in the activation conformation: effects of the Y1139 residue and S-adenosylmethionine on the B12 cofactor. | Journal of the American Chemical Society 20081203 |
Relationships between gene polymorphisms of folate-related proteins and vitamins and metabolites in pregnant women and neonates. | Clinica chimica acta; international journal of clinical chemistry 20081201 |
Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats. | Clinical nutrition (Edinburgh, Scotland) 20081201 |
Crystal structure of tRNA N2,N2-guanosine dimethyltransferase Trm1 from Pyrococcus horikoshii. | Journal of molecular biology 20081121 |
Selective targeting of leukemic cell growth in vivo and in vitro using a gene silencing approach to diminish S-adenosylmethionine synthesis. | The Journal of biological chemistry 20081107 |
Antifungal activity of 25-azalanosterol against Candida species. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20081101 |
Assays for S-adenosylmethionine (AdoMet/SAM)-dependent methyltransferases. | Current protocols in toxicology 20081101 |
Epigenetic alterations in the brains of Fisher 344 rats induced by long-term administration of folate/methyl-deficient diet. | Brain research 20081027 |
Effects of different glycerol feeding strategies on S-adenosyl-l-methionine biosynthesis by P(GAP)-driven Pichia pastoris overexpressing methionine adenosyltransferase. | Journal of biotechnology 20081010 |
Ergot alkaloid biosynthesis in Aspergillus fumigatus. Overproduction and biochemical characterization of a 4-dimethylallyltryptophan N-methyltransferase. | The Journal of biological chemistry 20081003 |
The transition from fatty liver to NASH associates with SAMe depletion in db/db mice fed a methionine choline-deficient diet. | Digestive diseases and sciences 20081001 |
A hydrophilic-interaction chromatography tandem mass spectrometry method for quantitation of serum s-adenosylmethionine in patients infected with human immunodeficiency virus. | Clinica chimica acta; international journal of clinical chemistry 20081001 |
Changes in S-adenosylmethionine and GSH homeostasis during endotoxemia in mice. | Laboratory investigation; a journal of technical methods and pathology 20081001 |
S-adenosylmethionine and proliferation: new pathways, new targets. | Biochemical Society transactions 20081001 |
Crystal structures of the SAM-III/S(MK) riboswitch reveal the SAM-dependent translation inhibition mechanism. | Nature structural & molecular biology 20081001 |
Discovery of sphingosine 1-O-methyltransferase in rat kidney and liver homogenates. | Acta pharmacologica Sinica 20081001 |
[Pre-L-methionine feeding strategy for S-adenosyl-L-methionine fermentative production]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20081001 |
Crystal structure of the Thermus thermophilus 16 S rRNA methyltransferase RsmC in complex with cofactor and substrate guanosine. | The Journal of biological chemistry 20080926 |
S-Adenosyl-L-methionine hydrolase (adenosine-forming), a conserved bacterial and archaeal protein related to SAM-dependent halogenases. | Chembiochem : a European journal of chemical biology 20080922 |
ThiC is an [Fe-S] cluster protein that requires AdoMet to generate the 4-amino-5-hydroxymethyl-2-methylpyrimidine moiety in thiamin synthesis. | Biochemistry 20080902 |
Complementary and alternative medicine in the treatment of bipolar disorder--a review of the evidence. | Journal of affective disorders 20080901 |
S-adenosyl-L-methionine decreases the elevated hepatotoxicity induced by Fas agonistic antibody plus acute ethanol pretreatment in mice. | Archives of biochemistry and biophysics 20080901 |
Elevated serum levels of S-adenosylhomocysteine, but not homocysteine, are associated with cardiovascular disease in stage 5 chronic kidney disease patients. | Clinica chimica acta; international journal of clinical chemistry 20080901 |
Decreased DNA methyltransferase 3A and 3B mRNA expression in peripheral blood mononuclear cells and increased plasma SAH concentration in adult patients with idiopathic thrombocytopenic purpura. | Journal of clinical immunology 20080901 |
The methylation, neurotransmitter, and antioxidant connections between folate and depression. | Alternative medicine review : a journal of clinical therapeutic 20080901 |
Wheat coleoptile endonuclease Wen2 is dependent on S-adenosyl-L-methionine and sensitive to DNA methylation status. | Biochemistry. Biokhimiia 20080901 |
Are nutritional supplements ready for prime time? | The Journal of clinical psychiatry 20080901 |
Mechanistic study on the reaction of a radical SAM dehydrogenase BtrN by electron paramagnetic resonance spectroscopy. | Biochemistry 20080826 |
3-Methylarginine from Pseudomonas syringae pv. syringae 22d/93 suppresses the bacterial blight caused by its close relative Pseudomonas syringae pv. glycinea. | Chembiochem : a European journal of chemical biology 20080811 |
Lentivirus mediated shRNA interference targeting MAT2B induces growth-inhibition and apoptosis in hepatocelluar carcinoma. | World journal of gastroenterology 20080807 |
Association between decreased vitamin levels and MTHFR, MTR and MTRR gene polymorphisms as determinants for elevated total homocysteine concentrations in pregnant women. | European journal of clinical nutrition 20080801 |
S-adenosyl-L-methionine attenuates oxidative stress and hepatic stellate cell activation in an ethanol-LPS-induced fibrotic rat model. | Shock (Augusta, Ga.) 20080801 |
Deficiency in l-serine deaminase results in abnormal growth and cell division of Escherichia coli K-12. | Molecular microbiology 20080801 |
Photoaffinity labeling and mutational analysis of 24-C-sterol methyltransferase defines the AdoMet binding site. | Lipids 20080801 |
Maternal global methylation status and risk of congenital heart diseases. | Obstetrics and gynecology 20080801 |
Analysis of AI-2/LuxS-dependent transcription in Campylobacter jejuni strain 81-176. | Foodborne pathogens and disease 20080801 |
Melatonin exerts a more potent effect than S-adenosyl-l-methionine against iron metabolism disturbances, oxidative stress and tissue injury induced by obstructive jaundice in rats. | Chemico-biological interactions 20080730 |
S-Adenosyl-l-methionine activates the cardiac ryanodine receptor. | Biochemical and biophysical research communications 20080711 |
Interplay between cellular methyl metabolism and adaptive efflux during oncogenic transformation from chronic arsenic exposure in human cells. | The Journal of biological chemistry 20080711 |
Structural, functional and calorimetric investigation of MosA, a dihydrodipicolinate synthase from Sinorhizobium meliloti l5-30, does not support involvement in rhizopine biosynthesis. | Chembiochem : a European journal of chemical biology 20080702 |
Random mutagenesis and recombination of sam1 gene by integrating error-prone PCR with staggered extension process. | Biotechnology letters 20080701 |
A decrease in S-adenosyl-L-methionine potentiates arachidonic acid cytotoxicity in primary rat hepatocytes enriched in CYP2E1. | Molecular and cellular biochemistry 20080701 |
Hyperglycemia-induced membrane lipid peroxidation and elevated homocysteine levels are poorly attenuated by exogenous folate in embryonic chick brains. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20080701 |
Juvenile hormone acid O-methyltransferase in Drosophila melanogaster. | Insect biochemistry and molecular biology 20080701 |
Reduced brain choline in homocystinuria due to remethylation defects. | Neurology 20080701 |
S-adenosylmethionine mediates glutathione efficacy by increasing glutathione S-transferase activity: implications for S-adenosyl methionine as a neuroprotective dietary supplement. | Journal of Alzheimer's disease : JAD 20080701 |
Anaerobic sulfatase-maturating enzymes, first dual substrate radical S-adenosylmethionine enzymes. | The Journal of biological chemistry 20080627 |
Crystal structures of human 108V and 108M catechol O-methyltransferase. | Journal of molecular biology 20080627 |
Product specificity and mechanism of protein lysine methyltransferases: insights from the histone lysine methyltransferase SET8. | Biochemistry 20080624 |
Ethanol inhibits methionine adenosyltransferase II activity and S-adenosylmethionine biosynthesis and enhances caspase-3-dependent cell death in T lymphocytes: relevance to alcohol-induced immunosuppression. | The Journal of nutritional biochemistry 20080601 |
Riboswitch effectors as protein enzyme cofactors. | RNA (New York, N.Y.) 20080601 |
The biochemical structure and function of methylenetetrahydrofolate reductase provide the rationale to interpret the epidemiological results on the risk for infants with Down syndrome. | American journal of medical genetics. Part A 20080601 |
Nonsurgical resolution of gallbladder mucocele in two dogs. | Journal of the American Veterinary Medical Association 20080601 |
S-adenosylmethionine inhibits lipopolysaccharide-induced gene expression via modulation of histone methylation. | Hepatology (Baltimore, Md.) 20080501 |
An allosteric mechanism for switching between parallel tracks in mammalian sulfur metabolism. | PLoS computational biology 20080501 |
Exploring the mechanisms behind S-adenosylmethionine (SAMe) in the treatment of osteoarthritis. | Critical reviews in food science and nutrition 20080501 |
Comparison of the effects of buthioninesulfoximine and phorone on the metabolism of sulfur-containing amino acids in rat liver. | Biochemical and biophysical research communications 20080418 |
A kinetic study of human protein arginine N-methyltransferase 6 reveals a distributive mechanism. | The Journal of biological chemistry 20080411 |
Betaine-homocysteine S-methyltransferase-2 is an S-methylmethionine-homocysteine methyltransferase. | The Journal of biological chemistry 20080404 |
Homocysteine, S-adenosylmethionine and S-adenosylhomocysteine are associated with retinal microvascular abnormalities: the Hoorn Study. | Clinical science (London, England : 1979) 20080401 |
S-Adenosylmethionine induces BldH and activates secondary metabolism by involving the TTA-codon control of bldH expression in Streptomyces lividans. | Archives of microbiology 20080401 |
B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice. | Molecular and cellular neurosciences 20080401 |
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice. | Hepatology (Baltimore, Md.) 20080401 |
Overexpression of yeast S-adenosylmethionine synthetase metK in Streptomyces actuosus leads to increased production of nosiheptide. | Applied microbiology and biotechnology 20080401 |
Dietary and genetic compromise in folate availability reduces acetylcholine, cognitive performance and increases aggression: critical role of S-adenosyl methionine. | The journal of nutrition, health & aging 20080401 |
The differential NF-kB modulation by S-adenosyl-L-methionine, N-acetylcysteine and quercetin on the promotion stage of chemical hepatocarcinogenesis. | Free radical research 20080401 |
Riboswitches that sense S-adenosylmethionine and S-adenosylhomocysteine. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20080401 |
Oxygen vectors used for S-adenosylmethionine production in recombinant Pichia pastoris with sorbitol as supplemental carbon source. | Journal of bioscience and bioengineering 20080401 |
Riboswitches that sense S-adenosylhomocysteine and activate genes involved in coenzyme recycling. | Molecular cell 20080328 |
Biochemical and genetic analysis of the phosphoethanolamine methyltransferase of the human malaria parasite Plasmodium falciparum. | The Journal of biological chemistry 20080321 |
Mechanism and tissue specificity of nicotine-mediated lung S-adenosylmethionine reduction. | The Journal of biological chemistry 20080321 |
Folate deprivation increases tau phosphorylation by homocysteine-induced calcium influx and by inhibition of phosphatase activity: Alleviation by S-adenosyl methionine. | Brain research 20080314 |
Reactivity and reaction order in acylhomoserine lactone formation by Pseudomonas aeruginosa RhlI. | Biochemistry 20080304 |
Beneficial drugs for liver diseases. | Journal of applied toxicology : JAT 20080301 |
Homocysteine-mediated PPARalpha,gamma DNA methylation and its potential pathogenic mechanism in monocytes. | DNA and cell biology 20080301 |
Mitochondrial Iba57p is required for Fe/S cluster formation on aconitase and activation of radical SAM enzymes. | Molecular and cellular biology 20080301 |
Ribosome stacking defines CGS1 mRNA degradation sites during nascent peptide-mediated translation arrest. | Plant & cell physiology 20080301 |
S-Adenosylmethionine in cell growth, apoptosis and liver cancer. | Journal of gastroenterology and hepatology 20080301 |
[Protection effects of S-adenosyl-L-methionine on lead-exposed rats during development and its mechanism of long-term potentiation]. | Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20080301 |
A universal competitive fluorescence polarization activity assay for S-adenosylmethionine utilizing methyltransferases. | Analytical biochemistry 20080215 |
Alpha anomer of 5-aza-2'-deoxycytidine down-regulates hTERT mRNA expression in human leukemia HL-60 cells. | Biochemical pharmacology 20080215 |
Folding of the SAM aptamer is determined by the formation of a K-turn-dependent pseudoknot. | Biochemistry 20080212 |
Comparison of S-adenosyl-L-methionine (SAMe) and N-acetylcysteine (NAC) protective effects on hepatic damage when administered after acetaminophen overdose. | Toxicology 20080203 |
S-adenosylmethionine and its products. | Amino acids 20080201 |
Folate status and S-adenosylmethionine/S-adenosylhomocysteine ratio in colorectal adenocarcinoma in humans. | European journal of clinical nutrition 20080201 |
Evaluation of nutritional and genetic determinants of total homocysteine, methylmalonic acid and S-adenosylmethionine/S-adenosylhomocysteine values in Brazilian childbearing-age women. | Clinica chimica acta; international journal of clinical chemistry 20080201 |
S-adenosylmethionine prevents Mallory Denk body formation in drug-primed mice by inhibiting the epigenetic memory. | Hepatology (Baltimore, Md.) 20080201 |
Complementary medicines in pediatric bipolar disorder. | Minerva pediatrica 20080201 |
Crystal structure and mutational study of a unique SpoU family archaeal methylase that forms 2'-O-methylcytidine at position 56 of tRNA. | Journal of molecular biology 20080125 |
The histamine N-methyltransferase T105I polymorphism affects active site structure and dynamics. | Biochemistry 20080122 |
Dietary supplements for osteoarthritis. | American family physician 20080115 |
S-adenosyl L-methionine inhibits azoxymethane-induced colonic aberrant crypt foci in F344 rats and suppresses human colon cancer Caco-2 cell growth in 3D culture. | International journal of cancer 20080101 |
Ethanol-induced increased endogenous homocysteine levels and decreased ratios of SAM/SAH are only partially attenuated by exogenous glycine in developing chick brains. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080101 |
Discovery and characterization of a marine bacterial SAM-dependent chlorinase. | Nature chemical biology 20080101 |
Expression of secreted His-tagged S-adenosylmethionine synthetase in the methylotrophic yeast Pichia pastoris and its characterization, one-step purification, and immobilization. | Biotechnology progress 20080101 |
Mammalian cytosine DNA methyltransferase Dnmt1: enzymatic mechanism, novel mechanism-based inhibitors, and RNA-directed DNA methylation. | Current medicinal chemistry 20080101 |
Detection and quantitation of the activity of DNA methyltransferases using a biotin/avidin microplate assay. | Methods in molecular biology (Clifton, N.J.) 20080101 |
The Radical SAM Superfamily. | Critical reviews in biochemistry and molecular biology 20080101 |
[Pathogenesis and progress in treatment of neonatal total parenteral nutrition-associated cholestasis]. | Zhonghua er ke za zhi = Chinese journal of pediatrics 20080101 |
Antiapoptotic role of S-adenosyl-l-methionine against hydrochloric acid induced cell death in Saccharomyces cerevisiae. | Biochimica et biophysica acta 20080101 |
Effect of S-adenosylmethionine tablets on the reduction of age-related mental decline in dogs: a double-blinded, placebo-controlled trial. | Veterinary therapeutics : research in applied veterinary medicine 20080101 |
Methylation status in healthy subjects with normal and high serum folate concentration. | Nutrition (Burbank, Los Angeles County, Calif.) 20080101 |
S-Adenosylhomocysteine hydrolase overexpression in HEK-293 cells: effect on intracellular adenosine levels, cell viability, and DNA methylation. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20080101 |
Transition state analogues in quorum sensing and SAM recycling. | Nucleic acids symposium series (2004) 20080101 |
Methionine metabolism in an animal model of sepsis. | Clinical chemistry and laboratory medicine 20080101 |
Requirement of RIZ1 for cancer prevention by methyl-balanced diet. | PloS one 20080101 |
Human polycomb 2 protein is a SUMO E3 ligase and alleviates substrate-induced inhibition of cystathionine beta-synthase sumoylation. | PloS one 20080101 |
Hypermethylation of Fads2 and altered hepatic fatty acid and phospholipid metabolism in mice with hyperhomocysteinemia. | The Journal of biological chemistry 20071221 |
Characterization and mechanistic study of a radical SAM dehydrogenase in the biosynthesis of butirosin. | Journal of the American Chemical Society 20071212 |
Cadmium induced oxidative stress in soybean plants also by the accumulation of delta-aminolevulinic acid. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20071201 |
Influence of preconditioning-like hypoxia on the liver of developing methyl-deficient rats. | American journal of physiology. Endocrinology and metabolism 20071201 |
Stability of plasma homocysteine, S-adenosylmethionine, and S-adenosylhomocysteine in EDTA, acidic citrate, and Primavette collection tubes. | Clinical chemistry 20071201 |
Mechanism of enzymatic fluorination in Streptomyces cattleya. | Journal of the American Chemical Society 20071128 |
Binding energy in the one-electron reductive cleavage of S-adenosylmethionine in lysine 2,3-aminomutase, a radical SAM enzyme. | Biochemistry 20071113 |
AdoMet-dependent methyl-transfer: Glu119 is essential for DNA C5-cytosine methyltransferase M.HhaI. | Journal of molecular biology 20071109 |
The many flavors of hyperhomocyst(e)inemia: insights from transgenic and inhibitor-based mouse models of disrupted one-carbon metabolism. | Antioxidants & redox signaling 20071101 |
Mechanisms of protection by the betaine-homocysteine methyltransferase/betaine system in HepG2 cells and primary mouse hepatocytes. | Hepatology (Baltimore, Md.) 20071101 |
S-adenosylmethionine attenuates oxidative liver injury in micropigs fed ethanol with a folate-deficient diet. | Alcoholism, clinical and experimental research 20071101 |
Glycine N-methyltransferase-/- mice develop chronic hepatitis and glycogen storage disease in the liver. | Hepatology (Baltimore, Md.) 20071101 |
[Cholestasis of pregnancy]. | Gastroenterologia y hepatologia 20071101 |
Continuous enzymatic assay for histone lysine methyltransferases. | BioTechniques 20071101 |
Genetic characterization of two S-adenosylmethionine-induced ABC transporters reveals their roles in modulations of secondary metabolism and sporulation in Streptomyces coelicolor M145. | Journal of microbiology and biotechnology 20071101 |
S-adenosylmethionine-dependent protein methylation in mammalian cytosol via tyrphostin modification by catechol-O-methyltransferase. | The Journal of biological chemistry 20071019 |
Depletion of S-adenosyl-l-methionine with cycloleucine potentiates cytochrome P450 2E1 toxicity in primary rat hepatocytes. | Archives of biochemistry and biophysics 20071015 |
Crystal structure of Plasmodium falciparum spermidine synthase in complex with the substrate decarboxylated S-adenosylmethionine and the potent inhibitors 4MCHA and AdoDATO. | Journal of molecular biology 20071012 |
Crystal structure of the radical SAM enzyme catalyzing tricyclic modified base formation in tRNA. | Journal of molecular biology 20071005 |
The import of S-adenosylmethionine into the Golgi apparatus is required for the methylation of homogalacturonan. | Plant physiology 20071001 |
S-adenosylmethionine as a biomarker for the early detection of lung cancer. | Chest 20071001 |
Self-sacrifice in radical S-adenosylmethionine proteins. | Current opinion in chemical biology 20071001 |
S-adenosyl-L-methionine:magnesium-protoporphyrin IX O-methyltransferase from Rhodobacter capsulatus: mechanistic insights and stimulation with phospholipids. | The Biochemical journal 20070915 |
Study of bacteriophage T4-encoded Dam DNA (adenine-N6)-methyltransferase binding with substrates by rapid laser UV cross-linking. | The Journal of biological chemistry 20070907 |
Supranormal dietary folic acid supplementation: effects on methionine metabolism in weanling rats. | The British journal of nutrition 20070901 |
Crystal structure of SAM-dependent O-methyltransferase from pathogenic bacterium Leptospira interrogans. | Journal of structural biology 20070901 |
Marked elevation in homocysteine and homocysteine sulfinic acid in the cerebrospinal fluid of lymphoma patients receiving intensive treatment with methotrexate. | International journal of clinical pharmacology and therapeutics 20070901 |
[Efficacy and safety of heptral, vitamin B6 and folic acid during toxic hepatitis induced by CCL4]. | Georgian medical news 20070901 |
Two threonine residues required for role of AfsKav in controlling morphogenesis and avermectin production in Streptomyces avermitilis. | Journal of microbiology and biotechnology 20070901 |
Structure-based activity prediction for an enzyme of unknown function. | Nature 20070816 |
The carboxyl-terminal extension of yeast tRNA m5C methyltransferase enhances the catalytic efficiency of the amino-terminal domain. | The Journal of biological chemistry 20070810 |
Homocysteine affects cardiomyocyte viability: concentration-dependent effects on reversible flip-flop, apoptosis and necrosis. | Apoptosis : an international journal on programmed cell death 20070801 |
Genetic polymorphisms in one-carbon metabolism: associations with CpG island methylator phenotype (CIMP) in colon cancer and the modifying effects of diet. | Carcinogenesis 20070801 |
Folate deprivation increases presenilin expression, gamma-secretase activity, and Abeta levels in murine brain: potentiation by ApoE deficiency and alleviation by dietary S-adenosyl methionine. | Journal of neurochemistry 20070801 |
Testosterone regulation of renal cystathionine beta-synthase: implications for sex-dependent differences in plasma homocysteine levels. | American journal of physiology. Renal physiology 20070801 |
Reactivation of methionine synthase from Thermotoga maritima (TM0268) requires the downstream gene product TM0269. | Protein science : a publication of the Protein Society 20070801 |
Homocysteine-mediated expression of SAHH, DNMTs, MBD2, and DNA hypomethylation potential pathogenic mechanism in VSMCs. | DNA and cell biology 20070801 |
Nutraceuticals in the management of osteoarthritis. | Orthopedics 20070801 |
S-adenosyl-L-methionine-dependent methyl transfer: observable precatalytic intermediates during DNA cytosine methylation. | Biochemistry 20070731 |
S-adenosyl methionine protects ob/ob mice from CYP2E1-mediated liver injury. | American journal of physiology. Gastrointestinal and liver physiology 20070701 |
S-adenosylmethionine attenuates hepatic lipid synthesis in micropigs fed ethanol with a folate-deficient diet. | Alcoholism, clinical and experimental research 20070701 |
Identification of a ubiG-like gene involved in ubiquinone biosynthesis from Chlamydophila pneumoniae AR39. | Letters in applied microbiology 20070701 |
Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells. | Gastroenterology 20070701 |
Functional characterization of the recombinant N-methyltransferase domain from the multienzyme enniatin synthetase. | Chembiochem : a European journal of chemical biology 20070618 |
Protein interactions in the human methionine synthase-methionine synthase reductase complex and implications for the mechanism of enzyme reactivation. | Biochemistry 20070612 |
Accumulation of proteins bearing atypical isoaspartyl residues in livers of alcohol-fed rats is prevented by betaine administration: effects on protein-L-isoaspartyl methyltransferase activity. | Journal of hepatology 20070601 |
Prevention of brain disease from severe 5,10-methylenetetrahydrofolate reductase deficiency. | Molecular genetics and metabolism 20070601 |
Structural bases for substrate recognition and activity in Meaban virus nucleoside-2'-O-methyltransferase. | Protein science : a publication of the Protein Society 20070601 |
Effect of vitamin B6 availability on serine hydroxymethyltransferase in MCF-7 cells. | Archives of biochemistry and biophysics 20070601 |
S-adenosylmethionine exerts a protective effect against thioacetamide-induced injury in primary cultures of rat hepatocytes. | Alternatives to laboratory animals : ATLA 20070601 |
gamma-Secretase is differentially modulated by alterations of homocysteine cycle in neuroblastoma and glioblastoma cells. | Journal of Alzheimer's disease : JAD 20070601 |
Making the connections--the crucial role of metabolite transporters at the interface between chloroplast and cytosol. | FEBS letters 20070525 |
The diverse members of the mitochondrial carrier family in plants. | FEBS letters 20070525 |
DNA methylation status is not impaired in treated cystathionine beta-synthase (CBS) deficient patients. | Molecular genetics and metabolism 20070501 |
Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. | Molecular genetics and metabolism 20070501 |
Role of S-adenosyl-L-methionine in liver health and injury. | Hepatology (Baltimore, Md.) 20070501 |
Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: a randomized controlled study. | Neurology 20070424 |
A pathogenic linked mutation in the catalytic core of human cystathionine beta-synthase disrupts allosteric regulation and allows kinetic characterization of a full-length dimer. | Biochemistry 20070403 |
Repair of alkylated DNA: recent advances. | DNA repair 20070401 |
Folate restriction and methylenetetrahydrofolate reductase 677T polymorphism decreases adoMet synthesis via folate-dependent remethylation in human-transformed lymphoblasts. | Leukemia 20070401 |
Consideration of betaine and one-carbon sources of N5-methyltetrahydrofolate for use in homocystinuria and neural tube defects. | The American journal of clinical nutrition 20070401 |
Abnormal folate metabolism in foetuses affected by neural tube defects. | Brain : a journal of neurology 20070401 |
Recognition of age-damaged (R,S)-adenosyl-L-methionine by two methyltransferases in the yeast Saccharomyces cerevisiae. | The Journal of biological chemistry 20070323 |
S-Adenosylmethionine in protozoan parasites: functions, synthesis and regulation. | Molecular and biochemical parasitology 20070301 |
S-adenosylmethionine as an oxidant: the radical SAM superfamily. | Trends in biochemical sciences 20070301 |
Nonalcoholic fatty liver disease: predisposing factors and the role of nutrition. | The Journal of nutritional biochemistry 20070301 |
S-adenosylmethionine and radical-based catalysis. | Amino acids 20070201 |
Betaine attenuates alcoholic steatosis by restoring phosphatidylcholine generation via the phosphatidylethanolamine methyltransferase pathway. | Journal of hepatology 20070201 |
Glutamate 2,3-aminomutase: a new member of the radical SAM superfamily of enzymes. | Biochimica et biophysica acta 20070201 |
Crystal structure and solution characterization of the activation domain of human methionine synthase. | The FEBS journal 20070201 |
Adenosine metabolism and its effect on methylation potential in cultured cells: methodological considerations. | Cellular and molecular biology (Noisy-le-Grand, France) 20070121 |
Role of S-adenosylhomocysteine hydrolase in adenosine-induced apoptosis in HepG2 cells. | Experimental cell research 20070115 |
S-adenosyl methionine and DNA methyltransferase-1 mRNA overexpression in psychosis. | Neuroreport 20070108 |
Long term low-dose arsenic exposure induces loss of DNA methylation. | Biochemical and biophysical research communications 20070105 |
Modulation of DNA methyltransferase profile by methyl donor starvation followed by gamma irradiation. | Molecular and cellular biochemistry 20070101 |
Inhibition of human betaine-homocysteine methyltransferase expression by S-adenosylmethionine and methylthioadenosine. | The Biochemical journal 20070101 |
Global metabolic changes following loss of a feedback loop reveal dynamic steady states of the yeast metabolome. | Metabolic engineering 20070101 |
Comparison of S-Adenosyl-L-methionine and N-acetylcysteine protective effects on acetaminophen hepatic toxicity. | The Journal of pharmacology and experimental therapeutics 20070101 |
Binding study of AfsK, a Ser/Thr kinase from Streptomyces coelicolor A3(2) and S-adenosyl-L-methionine. | FEMS microbiology letters 20070101 |
Allosteric monofunctional aspartate kinases from Arabidopsis. | The FEBS journal 20070101 |
Amino acids and the regulation of methyl balance in humans. | Current opinion in clinical nutrition and metabolic care 20070101 |
Emerging aspects of gut sulfur amino acid metabolism. | Current opinion in clinical nutrition and metabolic care 20070101 |
The role of methionine recycling for ethylene synthesis in Arabidopsis. | The Plant journal : for cell and molecular biology 20070101 |
Cysteine supplementation decreases plasma homocysteine concentration in rats fed on a low-casein diet in rats. | Bioscience, biotechnology, and biochemistry 20070101 |
Crystal structures of CbiL, a methyltransferase involved in anaerobic vitamin B biosynthesis, and CbiL in complex with S-adenosylhomocysteine--implications for the reaction mechanism. | The FEBS journal 20070101 |
A method to study the expression of DNA methyltransferases in aging systems in vitro. | Methods in molecular biology (Clifton, N.J.) 20070101 |
The role of one-carbon metabolism in schizophrenia and depression. | Harvard review of psychiatry 20070101 |
Effects of dietary supplementation with N-acetyl cysteine, acetyl-L-carnitine and S-adenosyl methionine on cognitive performance and aggression in normal mice and mice expressing human ApoE4. | Neuromolecular medicine 20070101 |
Metabolic regulatory properties of S-adenosylmethionine and S-adenosylhomocysteine. | Clinical chemistry and laboratory medicine 20070101 |
Wheat endonuclease WEN1 dependent on S-adenosyl-L-methionine and sensitive to DNA methylation status. | Epigenetics 20070101 |
Hydroxyl radical probing of tRNA (Gm18) methyltransferase [TrmH]-AdoMet-artificial tRNA ternary complex. | Nucleic acids symposium series (2004) 20070101 |
Metabolic signature of breast cancer cell line MCF-7: profiling of modified nucleosides via LC-IT MS coupling. | BMC biochemistry 20070101 |
Potentiation of arsenic neurotoxicity by folate deprivation: protective role of S-adenosyl methionine. | Nutritional neuroscience 20070101 |
Priorities in the discovery of the implications of water channels in epilepsy and Duchenne muscular dystrophy. | Cellular and molecular biology (Noisy-le-Grand, France) 20061231 |
Catalysis in glycine N-methyltransferase: testing the electrostatic stabilization and compression hypothesis. | Biochemistry 20061219 |
Nitric oxide modulates glutathione synthesis during endotoxemia. | Free radical biology & medicine 20061215 |
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism. | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20061205 |
Protein arginine methylation: Cellular functions and methods of analysis. | Biochimica et biophysica acta 20061201 |
Suppression of TNF-alpha production by S-adenosylmethionine in human mononuclear leukocytes is not mediated by polyamines. | Biological chemistry 20061201 |
S-adenosylmethionine (SAM)-accumulating sake yeast suppresses acute alcohol-induced liver injury in mice. | Bioscience, biotechnology, and biochemistry 20061201 |
Structural basis for dual functionality of isoflavonoid O-methyltransferases in the evolution of plant defense responses. | The Plant cell 20061201 |
Supplementation with apple juice attenuates presenilin-1 overexpression during dietary and genetically-induced oxidative stress. | Journal of Alzheimer's disease : JAD 20061201 |
Increase in S-adenosylhomocysteine content and its effect on the S-adenosylhomocysteine hydrolase activity under transient high plasma homocysteine levels in rats. | Journal of nutritional science and vitaminology 20061201 |
Quantitative analysis of s-adenosylmethionine and s-adenosylhomocysteine in neurulation-stage mouse embryos by liquid chromatography tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061121 |
Structural basis for the differential regulation of DNA by the methionine repressor MetJ. | The Journal of biological chemistry 20061110 |
Functional categorization of the conserved basic amino acid residues in TrmH (tRNA (Gm18) methyltransferase) enzymes. | The Journal of biological chemistry 20061110 |
DLPC and SAMe prevent alpha1(I) collagen mRNA up-regulation in human hepatic stellate cells, whether caused by leptin or menadione. | Biochemical and biophysical research communications 20061110 |
Mild folate deficiency induces a proatherosclerotic phenotype in endothelial cells. | Atherosclerosis 20061101 |
S-adenosylmethionine prevents chronic alcohol-induced mitochondrial dysfunction in the rat liver. | American journal of physiology. Gastrointestinal and liver physiology 20061101 |
Molecular identification of an Arabidopsis S-adenosylmethionine transporter. Analysis of organ distribution, bacterial expression, reconstitution into liposomes, and functional characterization. | Plant physiology 20061101 |
Arabidopsis SAMT1 defines a plastid transporter regulating plastid biogenesis and plant development. | The Plant cell 20061101 |
PAGE separation of hemi-methylated or unmethylated oligonucleotide substrates to distinguish between maintenance and de novo DNA methyltranferase activity. | Journal of biochemical and biophysical methods 20061031 |
Tandem riboswitch architectures exhibit complex gene control functions. | Science (New York, N.Y.) 20061013 |
Interactions of cytokines, S-Adenosylmethionine, and S-Adenosylhomocysteine in alcohol-induced liver disease and immune suppression. | Journal of gastroenterology and hepatology 20061001 |
L-NAME has opposite effects on the productions of S-adenosylhomocysteine and S-adenosylmethionine in V12-H-Ras and M-CR3B-Ras pheochromocytoma cells. | Neurochemical research 20061001 |
Solvent-accessible cysteines in human cystathionine beta-synthase: crucial role of cysteine 431 in S-adenosyl-L-methionine binding. | Biochemistry 20060912 |
Characterization of an active spore photoproduct lyase, a DNA repair enzyme in the radical S-adenosylmethionine superfamily. | The Journal of biological chemistry 20060908 |
Exogenous glycine partially attenuates homocysteine-induced apoptosis and membrane peroxidation in chick embryos. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060901 |
Osteoarthritis. | Disease-a-month : DM 20060901 |
4-Hydroxyphenylacetate decarboxylases: properties of a novel subclass of glycyl radical enzyme systems. | Biochemistry 20060808 |
S-adenosylhomocysteine hydrolase deficiency in a 26-year-old man. | Journal of inherited metabolic disease 20060801 |
S-Adenosyl-L-methionine: beyond the universal methyl group donor. | Phytochemistry 20060801 |
Suppression of methionine-induced hyperhomocysteinemia by dietary eritadenine in rats. | Bioscience, biotechnology, and biochemistry 20060801 |
Folate, the methionine cycle, and Alzheimer's disease. | Journal of Alzheimer's disease : JAD 20060801 |
Dietary and genetically-induced oxidative stress alter tau phosphorylation: influence of folate and apolipoprotein E deficiency. | Journal of Alzheimer's disease : JAD 20060801 |
Gene silencing through methylation: an epigenetic intervention on Alzheimer disease. | Journal of Alzheimer's disease : JAD 20060801 |
The effect of S-adenosylmethionine on CNS gene expression studied by cDNA microarray analysis. | Journal of Alzheimer's disease : JAD 20060801 |
Homocysteine metabolism and various consequences of folate deficiency. | Journal of Alzheimer's disease : JAD 20060801 |
Crystal structures of BchU, a methyltransferase involved in bacteriochlorophyll c biosynthesis, and its complex with S-adenosylhomocysteine: implications for reaction mechanism. | Journal of molecular biology 20060721 |
Flipping off the riboswitch: RNA structures that control gene expression. | ACS chemical biology 20060721 |
S-adenosylmethionine regulates cytoplasmic HuR via AMP-activated kinase. | Gastroenterology 20060701 |
Structural biology: RNA switches function. | Nature 20060629 |
Structure of the S-adenosylmethionine riboswitch regulatory mRNA element. | Nature 20060629 |
Catalysis by the second class of tRNA(m1G37) methyl transferase requires a conserved proline. | Biochemistry 20060620 |
Differential regulation of the JNK/AP-1 pathway by S-adenosylmethionine and methylthioadenosine in primary rat hepatocytes versus HuH7 hepatoma cells. | American journal of physiology. Gastrointestinal and liver physiology 20060601 |
Tea polyphenol epigallocatechin-3-gallate inhibits ergosterol synthesis by disturbing folic acid metabolism in Candida albicans. | The Journal of antimicrobial chemotherapy 20060601 |
Tolcapone decreases plasma levels of S-adenosyl-L-homocysteine and homocysteine in treated Parkinson's disease patients. | European journal of clinical pharmacology 20060601 |
In vivo hydrolysis of S-adenosyl-L-methionine in Escherichia coli increases export of 5-methylthioribose. | Canadian journal of microbiology 20060601 |
The active conformation of avilamycin A is conferred by AviX12, a radical AdoMet enzyme. | The Journal of biological chemistry 20060526 |
S-adenosylmethionine but not glutathione protects against galactosamine-induced cytotoxicity in rat hepatocyte cultures. | Toxicology 20060515 |
Coupling between protein and reaction dynamics in enzymatic processes: application of Grote-Hynes Theory to catechol O-methyltransferase. | Journal of the American Chemical Society 20060510 |
Effects of diabetes and insulin on betaine-homocysteine S-methyltransferase expression in rat liver. | American journal of physiology. Endocrinology and metabolism 20060501 |
Maternal polymorphisms 677C-T and 1298A-C of MTHFR, and 66A-G MTRR genes: is there any relationship between polymorphisms of the folate pathway, maternal homocysteine levels, and the risk for having a child with Down syndrome? | American journal of medical genetics. Part A 20060501 |
In vivo hydrolysis of S-adenosylmethionine induces the met regulon of Escherichia coli. | Microbiology (Reading, England) 20060501 |
Determinants of the ubiquitin-mediated degradation of the Met4 transcription factor. | The Journal of biological chemistry 20060428 |
Insights into cephamycin biosynthesis: the crystal structure of CmcI from Streptomyces clavuligerus. | Journal of molecular biology 20060428 |
S-adenosyl-L-methionine for alcoholic liver diseases. | The Cochrane database of systematic reviews 20060419 |
Opposite action of S-adenosyl methionine and its metabolites on CYP2E1-mediated toxicity in pyrazole-induced rat hepatocytes and HepG2 E47 cells. | American journal of physiology. Gastrointestinal and liver physiology 20060401 |
S-adenosyl-L-methionine attenuates hepatotoxicity induced by agonistic Jo2 Fas antibody following CYP2E1 induction in mice. | The Journal of pharmacology and experimental therapeutics 20060401 |
S-adenosylmethionine: jack of all trades and master of everything? | Biochemical Society transactions 20060401 |
S-Adenosylmethionine and betaine correct hepatitis C virus induced inhibition of interferon signaling in vitro. | Hepatology (Baltimore, Md.) 20060401 |
Spectral and kinetic characterization of 7,8-diaminopelargonic acid synthase from Mycobacterium tuberculosis. | IUBMB life 20060401 |
S-adenosyl-methionine decreases ethanol-induced apoptosis in primary hepatocyte cultures by a c-Jun N-terminal kinase activity-independent mechanism. | World journal of gastroenterology 20060328 |
An enzyme-coupled continuous spectrophotometric assay for S-adenosylmethionine-dependent methyltransferases. | Analytical biochemistry 20060315 |
Cofactor dependence of reduction potentials for [4Fe-4S]2+/1+ in lysine 2,3-aminomutase. | Biochemistry 20060314 |
Catalytic properties and kinetic mechanism of human recombinant Lys-9 histone H3 methyltransferase SUV39H1: participation of the chromodomain in enzymatic catalysis. | Biochemistry 20060314 |
Natural product diversification using a non-natural cofactor analogue of S-adenosyl-L-methionine. | Journal of the American Chemical Society 20060308 |
Mice heterozygous for the Mdr2 gene demonstrate decreased PEMT activity and diminished steatohepatitis on the MCD diet. | Journal of hepatology 20060301 |
DLPC and SAMe combined prevent leptin-stimulated TIMP-1 production in LX-2 human hepatic stellate cells by inhibiting HO-mediated signal transduction. | Liver international : official journal of the International Association for the Study of the Liver 20060301 |
Let LuxS speak up in AI-2 signaling. | Trends in microbiology 20060301 |
Therapy of NAFLD: antioxidants and cytoprotective agents. | Journal of clinical gastroenterology 20060301 |
[Effect of feeding pre-L-methionine on high-cell-density fermentation for S-adenosyl-L-methionine production]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20060301 |
Differential effects of dietary selenium (se) and folate on methyl metabolism in liver and colon of rats. | Biological trace element research 20060301 |
[Ursodeoxycholic acid, S-adenosyl-L-methionine and their combinations in the treatment of gestational intrahepatic cholestasis (ICP)]. | Ceska gynekologie 20060301 |
[The impact of heptral, vitamin B6 and folic acid on the indices of hepatic biotransformation in toxic hepatitis]. | Georgian medical news 20060301 |
Allosteric threonine synthase. Reorganization of the pyridoxal phosphate site upon asymmetric activation through S-adenosylmethionine binding to a novel site. | The Journal of biological chemistry 20060224 |
The 108M polymorph of human catechol O-methyltransferase is prone to deformation at physiological temperatures. | Biochemistry 20060221 |
Synergistic protection by S-adenosylmethionine with vitamins C and E on liver injury induced by thioacetamide in rats. | Free radical biology & medicine 20060215 |
A new method for isolation of S-adenosylmethionine (SAM)-accumulating yeast. | Applied microbiology and biotechnology 20060201 |
Flavonoid 3'-O-methyltransferase from rice: cDNA cloning, characterization and functional expression. | Phytochemistry 20060201 |
The Elongator subunit Elp3 contains a Fe4S4 cluster and binds S-adenosylmethionine. | Molecular microbiology 20060201 |
Complementary medicines in psychiatry: review of effectiveness and safety. | The British journal of psychiatry : the journal of mental science 20060201 |
The fluorinase from Streptomyces cattleya is also a chlorinase. | Angewandte Chemie (International ed. in English) 20060123 |
Activation of a novel isoform of methionine adenosyl transferase 2A and increased S-adenosylmethionine turnover in lung epithelial cells exposed to hyperoxia. | Free radical biology & medicine 20060115 |
Characterization of a methionine adenosyltransferase over-expressing strain in the trypanosomatid Leishmania donovani. | Biochimica et biophysica acta 20060101 |
Protective effect of S-adenosylmethionine against galactosamine-induced injury of rat hepatocytes in primary culture. | Physiological research 20060101 |
Quantification of S-adenosyl methionine in microbial cell extracts. | Biotechnology letters 20060101 |
Chemical expansion of cofactor activity. | Nature chemical biology 20060101 |
Glutathione-enhancing agents protect against steatohepatitis in a dietary model. | Journal of biochemical and molecular toxicology 20060101 |
Vitamin B12 and methionine synthesis: a critical review. Is nature's most beautiful cofactor misunderstood? | BioFactors (Oxford, England) 20060101 |
Radical enzymes in anaerobes. | Annual review of microbiology 20060101 |
Randomized prospective comparative study of ursodeoxycholic acid and S-adenosyl-L-methionine in the treatment of intrahepatic cholestasis of pregnancy. | Journal of perinatal medicine 20060101 |
S-adenosylmethionine or 5'-methylthioadenosine are unable to prevent fumonisin B1 hepatotoxicity in mice despite increased oxidation in liver. | Journal of applied toxicology : JAT 20060101 |
Effect of cell cycle growth arrest on global DNA methylation status in human lung epithelial-like (A549) cells. | In vivo (Athens, Greece) 20060101 |
Structural studies of the purine and SAM binding riboswitches. | Cold Spring Harbor symposia on quantitative biology 20060101 |
Synthesis of S-adenosyl-L-methionine analogs and their use for sequence-specific transalkylation of DNA by methyltransferases. | Nature protocols 20060101 |
The role of nutritional therapy in alcoholic liver disease. | Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 20060101 |
Aspirin augments the concentration of endogenous hydrogen sulfide in mouse brain and liver. | Folia medica Cracoviensia 20060101 |
Procainamide is a specific inhibitor of DNA methyltransferase 1. | The Journal of biological chemistry 20051209 |
Inclusion of thiamine diphosphate and S-adenosylmethionine at their chemically active sites. | The Journal of organic chemistry 20051209 |
The role of phospholipid methylation in 1-methyl-4-phenyl-pyridinium ion (MPP+)-induced neurotoxicity in PC12 cells. | Neurotoxicology 20051201 |
In vitro and in vivo analysis of the major type I protein arginine methyltransferase from Trypanosoma brucei. | Molecular and biochemical parasitology 20051201 |
The crystal structure of a novel SAM-dependent methyltransferase PH1915 from Pyrococcus horikoshii. | Protein science : a publication of the Protein Society 20051201 |
The immediate-early ethylene response gene OsARD1 encodes an acireductone dioxygenase involved in recycling of the ethylene precursor S-adenosylmethionine. | The Plant journal : for cell and molecular biology 20051201 |
Inhibitory effect of Epimedium extract on S-adenosyl-L-homocysteine hydrolase and biomethylation. | Life sciences 20051126 |
Structural, mutagenic, and kinetic analysis of the binding of substrates and inhibitors of human phenylethanolamine N-methyltransferase. | Journal of medicinal chemistry 20051117 |
A deficiency in S-adenosylmethionine synthetase interrupts assembly of the septal ring in Escherichia coli K-12. | Molecular microbiology 20051101 |
Sequence specificity and role of proximal amino acids of the histone H3 tail on catalysis of murine G9A lysine 9 histone H3 methyltransferase. | Biochemistry 20051004 |
Effect of acute hyperhomocysteinemia on methylation potential of erythrocytes and on DNA methylation of lymphocytes in healthy male volunteers. | American journal of physiology. Renal physiology 20051001 |
Structural and functional comparison of HemN to other radical SAM enzymes. | Biological chemistry 20051001 |
The transmethylation cycle in the brain of Alzheimer patients. | Neuroscience letters 20050930 |
An escape from Italy, the discovery of S-adenosylmethionine, and the biosynthesis of creatine by Giulio L. Cantoni. 1953. | The Journal of biological chemistry 20050923 |
Biochemical characterization of the HydE and HydG iron-only hydrogenase maturation enzymes from Thermatoga maritima. | FEBS letters 20050912 |
Protective effect of S-adenosylmethionine on cellular and mitochondrial membranes of rat hepatocytes against tert-butylhydroperoxide-induced injury in primary culture. | Chemico-biological interactions 20050910 |
S-adenosylmethionine blocks collagen I production by preventing transforming growth factor-beta induction of the COL1A2 promoter. | The Journal of biological chemistry 20050902 |
Exogenous AdoMet and its analogue sinefungin differentially influence DNA cleavage by R.EcoP15I--usefulness in SAGE. | Biochemical and biophysical research communications 20050902 |
Diet-dependent survival of protein repair-deficient mice. | The Journal of nutritional biochemistry 20050901 |
Paracoccidioides brasiliensis, paracoccidioidomycosis, and antifungal antibiotics. | Current drug targets. Infectious disorders 20050901 |
A Leptospira interrogans enzyme with similarity to yeast Ste14p that methylates the 1-phosphate group of lipid A. | The Journal of biological chemistry 20050826 |
Radical S-adenosylmethionine enzyme coproporphyrinogen III oxidase HemN: functional features of the [4Fe-4S] cluster and the two bound S-adenosyl-L-methionines. | The Journal of biological chemistry 20050812 |
Stable-isotope dilution liquid chromatography-electrospray injection tandem mass spectrometry method for fast, selective measurement of S-adenosylmethionine and S-adenosylhomocysteine in plasma. | Clinical chemistry 20050801 |
Tyr152 plays a central role in the catalysis of 1-aminocyclopropane-1-carboxylate synthase. | Journal of experimental botany 20050801 |
Unusual pseudosubstrate specificity of a novel 3,5-dimethoxyphenol O-methyltransferase cloned from Ruta graveolens L. | Archives of biochemistry and biophysics 20050801 |
In nucleo enzymatic assays for the identification and characterization of histone modifying activities. | Methods (San Diego, Calif.) 20050801 |
A tertiary structural element in S box leader RNAs is required for S-adenosylmethionine-directed transcription termination. | Molecular microbiology 20050801 |
Structure of a class II TrmH tRNA-modifying enzyme from Aquifex aeolicus. | Acta crystallographica. Section F, Structural biology and crystallization communications 20050801 |
o-nitrobenzenesulfonamides in nucleoside synthesis: efficient 5'-aziridination of adenosine. | The Journal of organic chemistry 20050722 |
DNA cytosine C5 methyltransferase Dnmt1: catalysis-dependent release of allosteric inhibition. | Biochemistry 20050712 |
Removing a bottleneck in the Bacillus subtilis biotin pathway: bioA utilizes lysine rather than S-adenosylmethionine as the amino donor in the KAPA-to-DAPA reaction. | Biotechnology and bioengineering 20050705 |
Stable isotope dilution-based accurate comparative quantification of nitrogen-containing metabolites in Arabidopsis thaliana T87 cells using in vivo (15)N-isotope enrichment. | Bioscience, biotechnology, and biochemistry 20050701 |
Effects of betaine supplementation on hepatic metabolism of sulfur-containing amino acids in mice. | Journal of hepatology 20050601 |
Human embryonic stem cell methyl cycle enzyme expression: modelling epigenetic programming in assisted reproduction? | Reproductive biomedicine online 20050601 |
[Effect of heptral and folic acid on the hepatic functions during toxic hepatitis]. | Georgian medical news 20050601 |
Hepatic S-adenosylmethionine after maternal alcohol exposure on offspring rats. | Addiction biology 20050601 |
Encephalitozoon cuniculi mRNA cap (guanine N-7) methyltransferase: methyl acceptor specificity, inhibition BY S-adenosylmethionine analogs, and structure-guided mutational analysis. | The Journal of biological chemistry 20050527 |
Ligand-mediated anticodon conformational changes occur during tRNA methylation by a TrmD methyltransferase. | Biochemistry 20050503 |
Disturbed homocysteine and methionine cycle intermediates S-adenosylhomocysteine and S-adenosylmethionine are related to degree of renal insufficiency in type 2 diabetes. | Clinical chemistry 20050501 |
Effect of betaine supplementation on changes in hepatic metabolism of sulfur-containing amino acids and experimental cholestasis induced by alpha-naphthylisothiocyanate. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050501 |
Expression of iron-acquisition-related genes in iron-deficient rice is co-ordinately induced by partially conserved iron-deficiency-responsive elements. | Journal of experimental botany 20050501 |
Antioxidants as novel therapy in a murine model of colitis. | The Journal of nutritional biochemistry 20050501 |
Mechanistic studies on the metabolic scission of thiazolidinedione derivatives to acyclic thiols. | Chemical research in toxicology 20050501 |
Kinetics of homocysteine metabolism after moderate alcohol consumption. | Alcoholism, clinical and experimental research 20050501 |
S-adenosyl-L-methionine: transcellular transport and uptake by Caco-2 cells and hepatocytes. | The Journal of pharmacy and pharmacology 20050501 |
Effect of nicotine on lung S-adenosylmethionine and development of Pneumocystis pneumonia. | The Journal of biological chemistry 20050415 |
The impact of metabolism on DNA methylation. | Human molecular genetics 20050415 |
S-adenosylmethionine (SAMe) modulates interleukin-10 and interleukin-6, but not TNF, production via the adenosine (A2) receptor. | Biochimica et biophysica acta 20050415 |
Homocysteine alterations in experimental cholestasis and its subsequent cirrhosis. | Life sciences 20050408 |
Polyamine synthesis from proline in the developing porcine placenta. | Biology of reproduction 20050401 |
In vivo evidence for the specificity of Plasmodium falciparum phosphoethanolamine methyltransferase and its coupling to the Kennedy pathway. | The Journal of biological chemistry 20050401 |
mRNA guanylation catalyzed by the S-adenosylmethionine-dependent guanylyltransferase of bamboo mosaic virus. | The Journal of biological chemistry 20050401 |
S-adenosylmethionine and 5-methyltetrahydrofolate are associated with endothelial function after controlling for confounding by homocysteine: the Hoorn Study. | Arteriosclerosis, thrombosis, and vascular biology 20050401 |
Residues distal from the active site that alter enzyme function in M.HhaI DNA cytosine methyltransferase. | Journal of biomolecular structure & dynamics 20050401 |
Inhibition of CYP2E1 catalytic activity in vitro by S-adenosyl-L-methionine. | Biochemical pharmacology 20050401 |
Regulation of trehalose metabolism by Adox and AdoMet in Saccharomyces cerevisiae. | Indian journal of experimental biology 20050401 |
Effect of fasting on methionine adenosyltransferase expression and the methionine cycle in the mouse liver. | Journal of nutritional science and vitaminology 20050401 |
Alcohol and liver cancer. | Alcohol (Fayetteville, N.Y.) 20050401 |
Role of methionine adenosyltransferase and S-adenosylmethionine in alcohol-associated liver cancer. | Alcohol (Fayetteville, N.Y.) 20050401 |
Mechanistic investigations of lipoic acid biosynthesis in Escherichia coli: both sulfur atoms in lipoic acid are contributed by the same lipoyl synthase polypeptide. | Journal of the American Chemical Society 20050309 |
MTX-induced white matter changes are associated with polymorphisms of methionine metabolism. | Neurology 20050308 |
Relationship between S-adenosylmethionine, S-adenosylhomocysteine, asymmetric dimethylarginine, and endothelial function in healthy human subjects during experimental hyper- and hypohomocysteinemia. | Metabolism: clinical and experimental 20050301 |
Valproate corrects the schizophrenia-like epigenetic behavioral modifications induced by methionine in mice. | Biological psychiatry 20050301 |
Effect of piroxicam, metamizol, and S-adenosylmethionine in a murine model of experimental trichomoniasis. | Parasite (Paris, France) 20050301 |
Specificity and mechanism of RNA cap guanine-N2 methyltransferase (Tgs1). | The Journal of biological chemistry 20050211 |
Effect of S-adenosyl-L-methionine on the activation, proliferation and contraction of hepatic stellate cells. | European journal of pharmacology 20050210 |
Aclacinomycin 10-hydroxylase is a novel substrate-assisted hydroxylase requiring S-adenosyl-L-methionine as cofactor. | The Journal of biological chemistry 20050204 |
Chemopreventive N-(4-hydroxyphenyl)retinamide (fenretinide) targets deregulated NF-{kappa}B and Mat1A genes in the early stages of rat liver carcinogenesis. | Carcinogenesis 20050201 |
Folate transport gene inactivation in mice increases sensitivity to colon carcinogenesis. | Cancer research 20050201 |
Evaluation of the influence of S-adenosylmethionine on systemic and hepatic effects of prednisolone in dogs. | American journal of veterinary research 20050201 |
Lysophosphatidylcholine decreases locomotor activities and dopamine turnover rate in rats. | Neurotoxicology 20050101 |
Fetal alcohol exposure impairs alveolar macrophage function via decreased glutathione availability. | Pediatric research 20050101 |
Pyruvate formate-lyase activating enzyme: elucidation of a novel mechanism for glycyl radical formation. | Archives of biochemistry and biophysics 20050101 |
The novel structure and chemistry of iron-sulfur clusters in the adenosylmethionine-dependent radical enzyme biotin synthase. | Archives of biochemistry and biophysics 20050101 |
S-adenosylmethionine/homocysteine cycle alterations modify DNA methylation status with consequent deregulation of PS1 and BACE and beta-amyloid production. | Molecular and cellular neurosciences 20050101 |
Autotoxicity, methylation and a road to the prevention of Parkinson's disease. | Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia 20050101 |
The effect of methionine and S-adenosylmethionine on S-adenosylmethionine levels in the rat brain. | Journal of psychiatry & neuroscience : JPN 20050101 |
The role of cystathionine beta-synthase in homocysteine metabolism. | Antioxidants & redox signaling 20050101 |
Nonpharmacologic treatments for depression in patients with coronary heart disease. | Psychosomatic medicine 20050101 |
The effects of S-adenosylmethionine on clinical pathology and redox potential in the red blood cell, liver, and bile of clinically normal cats. | Journal of veterinary internal medicine 20050101 |
S-adenosylhomocysteine metabolism in different cell lines: effect of hypoxia and cell density. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20050101 |
Evidence for a second class of S-adenosylmethionine riboswitches and other regulatory RNA motifs in alpha-proteobacteria. | Genome biology 20050101 |
Natural history of S-adenosylmethionine-binding proteins. | BMC structural biology 20050101 |
Levodopa intake increases plasma levels of S-adenosylmethionine in treated patients with Parkinson disease. | Clinical neuropharmacology 20050101 |
Pathogenesis and treatment of alcoholic liver disease: progress over the last 50 years. | Roczniki Akademii Medycznej w Bialymstoku (1995) 20050101 |
Effect of S-adenosylmethionine on age-induced hepatocyte damage in old Wistar rats. | Biogerontology 20050101 |
Structural change of tRNA (Gm18) methyltransferase by binding of methyl donor analogues. | Nucleic acids symposium series (2004) 20050101 |
S-Adenosylmethionine (SAMe) attenuates acetaminophen hepatotoxicity in C57BL/6 mice. | Toxicology letters 20041230 |
Modulation of endotoxin stimulated interleukin-6 production in monocytes and Kupffer cells by S-adenosylmethionine (SAMe). | Cytokine 20041221 |
Salt stress enhances xylem development and expression of S-adenosyl-L-methionine synthase in lignifying tissues of tomato plants. | Planta 20041201 |
S-adenosyl-L-methionine (SAMe) as an adjunct for resistant major depressive disorder: an open trial following partial or nonresponse to selective serotonin reuptake inhibitors or venlafaxine. | Journal of clinical psychopharmacology 20041201 |
Bacteriophage T4Dam DNA-(adenine-N(6))-methyltransferase. Comparison of pre-steady state and single turnover methylation of 40-mer duplexes containing two (un)modified target sites. | The Journal of biological chemistry 20041126 |
MiaB protein is a bifunctional radical-S-adenosylmethionine enzyme involved in thiolation and methylation of tRNA. | The Journal of biological chemistry 20041112 |
Bioavailability and lack of toxicity of S-adenosyl-L-methionine (SAMe) in humans. | Pharmacotherapy 20041101 |
Modulation of methyl group metabolism by streptozotocin-induced diabetes and all-trans-retinoic acid. | The Journal of biological chemistry 20041029 |
Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine. | Biochemistry 20041026 |
Isotope and elemental effects indicate a rate-limiting methyl transfer as the initial step in the reaction catalyzed by Escherichia coli cyclopropane fatty acid synthase. | Biochemistry 20041026 |
DAL-1/4.1B tumor suppressor interacts with protein arginine N-methyltransferase 3 (PRMT3) and inhibits its ability to methylate substrates in vitro and in vivo. | Oncogene 20041014 |
Treatment of AIDS-associated myelopathy with L-methionine: a placebo-controlled study. | Neurology 20041012 |
SAM domains can utilize similar surfaces for the formation of polymers and closed oligomers. | Journal of molecular biology 20041001 |
S-adenosylmethionine radical enzymes. | Bioorganic chemistry 20041001 |
Structure and function of radical SAM enzymes. | Current opinion in chemical biology 20041001 |
Consequences of binding an S-adenosylmethionine analogue on the structure and dynamics of the thiopurine methyltransferase protein backbone. | Biochemistry 20040928 |
Mutational analysis of ThiH, a member of the radical S-adenosylmethionine (AdoMet) protein superfamily. | The Journal of biological chemistry 20040924 |
Escherichia coli lipoyl synthase binds two distinct [4Fe-4S] clusters per polypeptide. | Biochemistry 20040921 |
Widespread activation of antibiotic biosynthesis by S-adenosylmethionine in streptomycetes. | FEMS microbiology letters 20040915 |
The mechanism of target base attack in DNA cytosine carbon 5 methylation. | Biochemistry 20040914 |
Fusarin C biosynthesis in Fusarium moniliforme and Fusarium venenatum. | Chembiochem : a European journal of chemical biology 20040906 |
S-adenosylmethionine protects against intrabiliary glutathione degradation induced by long-term administration of cyclosporin A in the rat. | Toxicology 20040901 |
In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl) phenyl]methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. I. Role of cytochrome P450, methyltransferases, flavin monooxygenases, and esterases. | Drug metabolism and disposition: the biological fate of chemicals 20040901 |
In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl)-phenyl] methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. II. Identification of metabolites by liquid chromatography-tandem mass spectrometry. | Drug metabolism and disposition: the biological fate of chemicals 20040901 |
N2-methylation of guanosine at position 10 in tRNA is catalyzed by a THUMP domain-containing, S-adenosylmethionine-dependent methyltransferase, conserved in Archaea and Eukaryota. | The Journal of biological chemistry 20040827 |
S-adenosylmethionine and Pneumocystis. | FEMS microbiology letters 20040815 |
Improved rotorod performance and hyperactivity in mice deficient in a protein repair methyltransferase. | Behavioural brain research 20040812 |
Differential protein expression analysis of Leishmania major reveals novel roles for methionine adenosyltransferase and S-adenosylmethionine in methotrexate resistance. | The Journal of biological chemistry 20040806 |
Stopped-flow and mutational analysis of base flipping by the Escherichia coli Dam DNA-(adenine-N6)-methyltransferase. | Journal of molecular biology 20040806 |
Inhibition of lipopolysaccharide-stimulated TNF-alpha promoter activity by S-adenosylmethionine and 5'-methylthioadenosine. | American journal of physiology. Gastrointestinal and liver physiology 20040801 |
Dimethyl sulfoxide stimulates the catalytic activity of de novo DNA methyltransferase 3a (Dnmt3a) in vitro. | Bioorganic chemistry 20040801 |
S-Adenosylmethionine protects against acetaminophen-induced hepatotoxicity in mice. | Pharmacology 20040801 |
Autoregulation of the gene for cystathionine gamma-synthase in Arabidopsis: post-transcriptional regulation induced by S-adenosylmethionine. | Biochemical Society transactions 20040801 |
Homocysteine clearance and methylation flux rates in health and end-stage renal disease: association with S-adenosylhomocysteine. | American journal of physiology. Renal physiology 20040801 |
Nutrition and alcoholic liver disease. | Seminars in liver disease 20040801 |
How oligomerization contributes to the thermostability of an archaeon protein. Protein L-isoaspartyl-O-methyltransferase from Sulfolobus tokodaii. | The Journal of biological chemistry 20040730 |
Reversal of the hypomethylation status of urokinase (uPA) promoter blocks breast cancer growth and metastasis. | The Journal of biological chemistry 20040723 |
Effects of S-adenosylmethionine on intrabiliary glutathione degradation induced by long-term administration of cyclosporin A in the rat. | Toxicology 20040715 |
A method for connecting solution-phase enzyme activity assays with immobilized format analysis by mass spectrometry. | Analytical chemistry 20040715 |
S-adenosylmethionine and its metabolite induce apoptosis in HepG2 cells: Role of protein phosphatase 1 and Bcl-x(S). | Hepatology (Baltimore, Md.) 20040701 |
Inhibitors of polyamine metabolism: review article. | Amino acids 20040701 |
Metabolic and antiproliferative consequences of activated polyamine catabolism in LNCaP prostate carcinoma cells. | The Journal of biological chemistry 20040625 |
Small molecule regulators of protein arginine methyltransferases. | The Journal of biological chemistry 20040604 |
Lipoyl synthase requires two equivalents of S-adenosyl-L-methionine to synthesize one equivalent of lipoic acid. | Biochemistry 20040601 |
An origin for arsenobetaine involving bacterial formation of an arsenic-carbon bond. | FEMS microbiology letters 20040601 |
Characterization of glycine N-methyltransferase from rabbit liver. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20040601 |
S-Adenosyl methionine/S-adenosyl-L-homocysteine ratio determination by capillary electrophoresis employed as a monitoring tool for the antiviral effectiveness of adenosine analogs. | Electrophoresis 20040601 |
Preparation of carbocyclic S-adenosylazamethionine accompanied by a practical synthesis of (-)-aristeromycin. | The Journal of organic chemistry 20040528 |
Methionine metabolism in plants: chloroplasts are autonomous for de novo methionine synthesis and can import S-adenosylmethionine from the cytosol. | The Journal of biological chemistry 20040521 |
Antioxidant properties of S-adenosyl-L-methionine in Fe(2+)-initiated oxidations. | Free radical biology & medicine 20040515 |
Enzymatic fluorination in Streptomyces cattleya takes place with an inversion of configuration consistent with an SN2 reaction mechanism. | Chembiochem : a European journal of chemical biology 20040503 |
Methotrexate differentially affects growth of suspension and adherent cells. | The international journal of biochemistry & cell biology 20040501 |
Impaired liver regeneration in mice lacking methionine adenosyltransferase 1A. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501 |
S-adenosylmethionine: nothing goes to waste. | Trends in biochemical sciences 20040501 |
Levodopa elevates homocysteine: is this a problem? | Archives of neurology 20040501 |
Detecting selection using a single genome sequence of M. tuberculosis and P. falciparum. | Nature 20040429 |
Thiamine biosynthesis in Escherichia coli: in vitro reconstitution of the thiazole synthase activity. | The Journal of biological chemistry 20040423 |
Deletion of the Pemt gene increases progenitor cell mitosis, DNA and protein methylation and decreases calretinin expression in embryonic day 17 mouse hippocampus. | Brain research. Developmental brain research 20040419 |
Starvation response in mouse liver shows strong correlation with life-span-prolonging processes. | Physiological genomics 20040413 |
Post-translational formylglycine modification of bacterial sulfatases by the radical S-adenosylmethionine protein AtsB. | The Journal of biological chemistry 20040409 |
Synthesis and evaluation of analogues of S-adenosyl-L-methionine, as inhibitors of the E. coli cyclopropane fatty acid synthase. | Bioorganic & medicinal chemistry letters 20040405 |
Identification of the human mitochondrial S-adenosylmethionine transporter: bacterial expression, reconstitution, functional characterization and tissue distribution. | The Biochemical journal 20040401 |
Influence of an altered methylation potential on mRNA methylation and gene expression in HepG2 cells. | Experimental cell research 20040401 |
5'-methylthioadenosine modulates the inflammatory response to endotoxin in mice and in rat hepatocytes. | Hepatology (Baltimore, Md.) 20040401 |
Deep knot structure for construction of active site and cofactor binding site of tRNA modification enzyme. | Structure (London, England : 1993) 20040401 |
O-Methylation of benzaldehyde derivatives by 'lignin specific' caffeic acid 3-O-methyltransferase. | Phytochemistry 20040401 |
NMR regulatory analysis: determination and characterization of S-adenosyl-L-methionine in dietary supplements. | Die Pharmazie 20040401 |
[Analysis on therapeutic effect of Western and Chinese drug in treating intrahepatic cholestasis pregnancy]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20040401 |
Structural studies of inhibition of S-adenosylmethionine synthetase by slow, tight-binding intermediate and product analogues. | Biochemistry 20040330 |
Sequence-specific methyltransferase-induced labeling of DNA (SMILing DNA). | Chembiochem : a European journal of chemical biology 20040305 |
Update on dietary supplements for depression. | Harvard women's health watch 20040301 |
The inhibitory role of methylation on the binding characteristics of dopamine receptors and transporter. | Neuroscience research 20040301 |
Structure of protein phosphatase methyltransferase 1 (PPM1), a leucine carboxyl methyltransferase involved in the regulation of protein phosphatase 2A activity. | The Journal of biological chemistry 20040227 |
Crystal structure of the S-adenosylmethionine synthetase ternary complex: a novel catalytic mechanism of S-adenosylmethionine synthesis from ATP and Met. | Biochemistry 20040224 |
Characterization of the cofactor composition of Escherichia coli biotin synthase. | Biochemistry 20040224 |
Effect of L-dopa on plasma homocysteine in PD patients: relationship to B-vitamin status. | Neurology 20040224 |
Heterodimeric interactions among the 1-amino-cyclopropane-1-carboxylate synthase polypeptides encoded by the Arabidopsis gene family. | Proceedings of the National Academy of Sciences of the United States of America 20040224 |
Conserved and nonconserved residues in the substrate binding site of 7,8-diaminopelargonic acid synthase from Escherichia coli are essential for catalysis. | Biochemistry 20040210 |
Crystal structure and mechanism of a bacterial fluorinating enzyme. | Nature 20040205 |
Quantification of serum and urinary S-adenosylmethionine and S-adenosylhomocysteine by stable-isotope-dilution liquid chromatography-mass spectrometry. | Clinical chemistry 20040201 |
New concepts of the pathogenesis of alcoholic liver disease lead to novel treatments. | Current gastroenterology reports 20040201 |
Use of desferoxamine and S-adenosylmethionine to treat hemochromatosis in a red ruffed lemur (Varecia variegata ruber). | Comparative medicine 20040201 |
Structure and mechanism of mRNA cap (guanine-N7) methyltransferase. | Molecular cell 20040116 |
Cigarette smoke extract increases S-adenosylmethionine and cystathionine in human lung epithelial-like (A549) cells. | Chemico-biological interactions 20040115 |
A mathematical model of the methionine cycle. | Journal of theoretical biology 20040107 |
Crystal structure of biotin synthase, an S-adenosylmethionine-dependent radical enzyme. | Science (New York, N.Y.) 20040102 |
A randomised controlled trial of ursodeoxycholic acid and S-adenosyl-l-methionine in the treatment of gestational cholestasis. | BJOG : an international journal of obstetrics and gynaecology 20040101 |
Joint-supplement quality improving. | Health news (Waltham, Mass.) 20040101 |
L-deaza-5'-noraisteromycin. | Nucleosides, nucleotides & nucleic acids 20040101 |
S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. | BMC musculoskeletal disorders 20040101 |
[Efficacy of combined use of ursodeoxycholic acid and heptral in the treatment of primary biliary cirrhosis]. | Klinicheskaia meditsina 20040101 |
[Efficacy of combined administration of ursodeoxycholic acid and hepthral in the treatment of primary biliary cirrhosis]. | Klinicheskaia meditsina 20040101 |
Mutational analysis of basic residues in the N-terminus of the rRNA:m6A methyltransferase ErmC'. | Folia microbiologica 20040101 |
Protein methylation activates reconstituted ryanodine receptor-ca release channels from coronary artery myocytes. | Journal of vascular research 20040101 |
Techniques in protein methylation. | Methods in molecular biology (Clifton, N.J.) 20040101 |
Selected integrative medicine treatments for depression: considerations for women. | Journal of the American Medical Women's Association (1972) 20040101 |
S-adenosylhomocysteine hydrolase, S-adenosylmethionine, S-adenosylhomocysteine: correlations with ribavirin induced anemia. | Medical hypotheses 20040101 |
S-adenosylmethionine (SAM-e) for the treatment of depression in people living with HIV/AIDS. | BMC psychiatry 20040101 |
Methylation demand and homocysteine metabolism. | Advances in enzyme regulation 20040101 |
[Correction by 2-ethyl-6-methyl-3-hydroxypyridine succinate of the hepatotoxyc, caused at rats introduction tuberculostatics]. | Biomeditsinskaia khimiia 20040101 |
Dietary supplementation with 3-deaza adenosine, N-acetyl cysteine, and S-adenosyl methionine provide neuroprotection against multiple consequences of vitamin deficiency and oxidative challenge: relevance to age-related neurodegeneration. | Neuromolecular medicine 20040101 |
Effect of naturally occurring mutations in human glycine N-methyltransferase on activity and conformation. | Biochemical and biophysical research communications 20031226 |
Methyl deficiency causes reduction of the methyl-CpG-binding protein, MeCP2, in rat liver. | Carcinogenesis 20031201 |
Identification of the 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase required for coenzyme F(420) biosynthesis. | Archives of microbiology 20031201 |
S-adenosyl-methionine in depression: a comprehensive review of the literature. | Current psychiatry reports 20031201 |
RXRalpha-regulated liver SAMe and GSH levels influence susceptibility to alcohol-induced hepatotoxicity. | Experimental and molecular pathology 20031201 |
Regulation of methylbenzoate emission after pollination in snapdragon and petunia flowers. | The Plant cell 20031201 |
Crystal structure of coproporphyrinogen III oxidase reveals cofactor geometry of Radical SAM enzymes. | The EMBO journal 20031201 |
Inhibition mechanism of S-adenosylmethionine-induced movement deficits by prenylcysteine analogs. | Pharmacology, biochemistry, and behavior 20031201 |
Involvement of gene-diet/drug interaction in DNA methylation and its contribution to complex diseases: from cancer to schizophrenia. | Clinical genetics 20031201 |
Effects of dietary folate intake and folate binding protein-1 (Folbp1) on urinary speciation of sodium arsenate in mice. | Toxicology letters 20031130 |
Site-specific observation of acyl intermediate processing in thiotemplate biosynthesis by fourier transform mass spectrometry: the polyketide module of yersiniabactin synthetase. | Biochemistry 20031125 |
Identification and functional reconstitution of yeast mitochondrial carrier for S-adenosylmethionine. | The EMBO journal 20031117 |
Effect of salt stress on the metabolism of ethanolamine and choline in leaves of the betaine-producing mangrove species Avicennia marina. | Phytochemistry 20031101 |
Are SAMe and 5-HTP safe and effective treatments for depression? | Journal of psychiatry & neuroscience : JPN 20031101 |
Regulation of S-adenosylmethionine levels in Saccharomyces cerevisiae. | The Journal of biological chemistry 20031031 |
The mechanism of 7,8-diaminopelargonate synthase; the role of S-adenosylmethionine as the amino donor. | Organic & biomolecular chemistry 20031021 |
S-adenosyl methionine prevents promiscuous DNA cleavage by the EcoP1I type III restriction enzyme. | Journal of molecular biology 20031017 |
S-adenosyl-L-methionine: effects on brain bioenergetic status and transverse relaxation time in healthy subjects. | Biological psychiatry 20031015 |
Coordination and mechanism of reversible cleavage of S-adenosylmethionine by the [4Fe-4S] center in lysine 2,3-aminomutase. | Journal of the American Chemical Society 20031001 |
S-adenosylmethionine (SAMe) protects against acute alcohol induced hepatotoxicity in mice. | The Journal of nutritional biochemistry 20031001 |
Avoiding the road less traveled: how the topology of enzyme-substrate complexes can dictate product selection. | Accounts of chemical research 20031001 |
Melithiazol biosynthesis: further insights into myxobacterial PKS/NRPS systems and evidence for a new subclass of methyl transferases. | Chemistry & biology 20031001 |
Molecular dissection of the S-adenosylmethionine-binding site of phosphatidylethanolamine N-methyltransferase. | The Journal of biological chemistry 20030912 |
Biosynthesis of phytosterols. Kinetic mechanism for the enzymatic C-methylation of sterols. | The Journal of biological chemistry 20030905 |
Beta-peltatin 6-O-methyltransferase from suspension cultures of Linum nodiflorum. | Phytochemistry 20030901 |
Methenyltetrahydrofolate synthetase regulates folate turnover and accumulation. | The Journal of biological chemistry 20030808 |
Crystal structures of methionine adenosyltransferase complexed with substrates and products reveal the methionine-ATP recognition and give insights into the catalytic mechanism. | Journal of molecular biology 20030808 |
High-performance liquid chromatography determination of methionine adenosyltransferase activity using catechol-O-methyltransferase-coupled fluorometric detection. | Analytical biochemistry 20030801 |
L-DOPA biotransformation: correlations of dosage, erythrocyte catechol O-methyltransferase and platelet SULT1A3 activities with metabolic pathways in Parkinsonian patients. | Journal of neural transmission (Vienna, Austria : 1996) 20030801 |
Plasma homocysteine and S-adenosylmethionine in erythrocytes as determinants of carotid intima-media thickness: different effects in diabetic and non-diabetic individuals. The Hoorn Study. | Atherosclerosis 20030801 |
S-adenosyl-L-methionine is able to reverse micronucleus formation induced by sodium arsenite and other cytoskeleton disrupting agents in cultured human cells. | Mutation research 20030725 |
Catalytic mechanism of glycine N-methyltransferase. | Biochemistry 20030722 |
Isolation and characterisation of 5'-fluorodeoxyadenosine synthase, a fluorination enzyme from Streptomyces cattleya. | FEBS letters 20030717 |
Okadaic acid-induced, naringin-sensitive phosphorylation of glycine N-methyltransferase in isolated rat hepatocytes. | The Biochemical journal 20030715 |
Conformational dynamics of the active site loop of S-adenosylmethionine synthetase illuminated by site-directed spin labeling. | Archives of biochemistry and biophysics 20030715 |
Crystal complexes of a predicted S-adenosylmethionine-dependent methyltransferase reveal a typical AdoMet binding domain and a substrate recognition domain. | Protein science : a publication of the Protein Society 20030701 |
Structural studies of the interaction of S-adenosylmethionine with the [4Fe-4S] clusters in biotin synthase and pyruvate formate-lyase activating enzyme. | Protein science : a publication of the Protein Society 20030701 |
Synthetic decarboxylated S-adenosyl-L-methionine as a substrate for aminopropyl transferases. | Biological & pharmaceutical bulletin 20030701 |
Hepatic preconditioning after prolonged warm ischemia by means of S-adenosyl-L-methionine administration in pig liver transplantation from non-heart-beating donors. | Transplantation 20030627 |
The methyl donor S-Adenosylmethionine inhibits active demethylation of DNA: a candidate novel mechanism for the pharmacological effects of S-Adenosylmethionine. | The Journal of biological chemistry 20030606 |
Crystal structure of tRNA(m1G37)methyltransferase: insights into tRNA recognition. | The EMBO journal 20030602 |
A novel polyamine analog (SL-11093) inhibits growth of human prostate tumor xenografts in nude mice. | Cancer chemotherapy and pharmacology 20030601 |
S-adenosylmethionine (AdoMet) modulates endotoxin stimulated interleukin-10 production in monocytes. | American journal of physiology. Gastrointestinal and liver physiology 20030601 |
Adenosyl coenzyme and pH dependence of the [4Fe-4S]2+/1+ transition in lysine 2,3-aminomutase. | Archives of biochemistry and biophysics 20030601 |
L-methionine availability regulates expression of the methionine adenosyltransferase 2A gene in human hepatocarcinoma cells: role of S-adenosylmethionine. | The Journal of biological chemistry 20030530 |
Crystal structure of the avilamycin resistance-conferring methyltransferase AviRa from Streptomyces viridochromogenes. | Journal of molecular biology 20030523 |
Kinetic mechanism of the tRNA-modifying enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA). | Biochemistry 20030513 |
Efficiency of lignin biosynthesis: a quantitative analysis. | Annals of botany 20030501 |
Effect of acute betaine administration on hepatic metabolism of S-amino acids in rats and mice. | Biochemical pharmacology 20030501 |
Altered methionine metabolism in long living Ames dwarf mice. | Experimental gerontology 20030501 |
Presenilin 1 gene silencing by S-adenosylmethionine: a treatment for Alzheimer disease? | FEBS letters 20030424 |
Purification and kinetic characterization of the magnesium protoporphyrin IX methyltransferase from Synechocystis PCC6803. | The Biochemical journal 20030415 |
Cobalamin deficiency with and without neurologic abnormalities: differences in homocysteine and methionine metabolism. | Blood 20030415 |
Reaction mechanism and regulation of cystathionine beta-synthase. | Biochimica et biophysica acta 20030411 |
S-adenosylmethionine (SAMe) in a feline acetaminophen model of oxidative injury. | Journal of feline medicine and surgery 20030401 |
Insertional inactivation of the methionine s-methyltransferase gene eliminates the s-methylmethionine cycle and increases the methylation ratio. | Plant physiology 20030401 |
Simultaneous detection of S-adenosylmethionine and S-adenosylhomocysteine in mouse and rat tissues by capillary electrophoresis. | Electrophoresis 20030401 |
The generation of 5'-deoxyadenosyl radicals by adenosylmethionine-dependent radical enzymes. | Current opinion in chemical biology 20030401 |
Increased response of liver microsomal delta 6-desaturase activity to dietary methionine in rats. | Bioscience, biotechnology, and biochemistry 20030401 |
Isolation and characterization of 27-O-demethylrifamycin SV methyltransferase provides new insights into the post-PKS modification steps during the biosynthesis of the antitubercular drug rifamycin B by Amycolatopsis mediterranei S699. | Archives of biochemistry and biophysics 20030315 |
Control of adenosylmethionine-dependent radical generation in biotin synthase: a kinetic and thermodynamic analysis of substrate binding to active and inactive forms of BioB. | Biochemistry 20030311 |
A dimeric viral SET domain methyltransferase specific to Lys27 of histone H3. | Nature structural biology 20030301 |
[Hyperhomocysteinemia: an independent risk factor or a simple marker of vascular disease?. 1. Basic data]. | Pathologie-biologie 20030301 |
Effects of S-adenosylmethionine on hepatic regeneration after partial hepatectomy in the rat. | Journal of physiology and biochemistry 20030301 |
Dose-dependent biotransformation of arsenite in rats--not S-adenosylmethionine depletion impairs arsenic methylation at high dose. | Toxicology 20030201 |
[Enhancement of the production of SAM by overexpression of SAM synthetase in Pichia pastoris]. | Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20030201 |
Functional analysis of BamHI DNA cytosine-N4 methyltransferase. | Journal of molecular biology 20030124 |
Kinetic inhibitory profile of BIA 3-202, a novel fast tight-binding, reversible and competitive catechol-O-methyltransferase inhibitor. | European journal of pharmacology 20030124 |
Mechanism of histone lysine methyl transfer revealed by the structure of SET7/9-AdoMet. | The EMBO journal 20030115 |
Assay for the enantiomeric analysis of [2H1]-fluoroacetic acid: insight into the stereochemical course of fluorination during fluorometabolite biosynthesis in streptomyces cattleya. | Journal of the American Chemical Society 20030115 |
Alternative therapies for traditional disease states: osteoarthritis. | American family physician 20030115 |
Mapping and molecular modeling of S-adenosyl-L-methionine binding sites in N-methyltransferase domains of the multifunctional polypeptide cyclosporin synthetase. | The Journal of biological chemistry 20030110 |
Catechol-O-methyltransferase inhibition protects against 3,4-dihydroxyphenylalanine (DOPA) toxicity in primary mesencephalic cultures: new insights into levodopa toxicity. | Neurochemistry international 20030101 |
Role of S-adenosylmethionine in two experimental models of pancreatitis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030101 |
S-adenosylhomocysteine and the ratio of S-adenosylmethionine to S-adenosylhomocysteine are not related to folate, cobalamin and vitamin B6 concentrations. | European journal of clinical investigation 20030101 |
Leishmania donovani methionine adenosyltransferase. Role of cysteine residues in the recombinant enzyme. | European journal of biochemistry 20030101 |
Impact of Dnmt1 deficiency, with and without low folate diets, on tumor numbers and DNA methylation in Min mice. | Carcinogenesis 20030101 |
The effect of dietary folate on genomic and p53-specific DNA methylation in rat colon. | Carcinogenesis 20030101 |
[DNA-[N4-cytosine]-methyltransferase from Bacillus amyloliquefaciens: mechanism of action derived from steady state kinetics]. | Molekuliarnaia biologiia 20030101 |
Characterization of the cofactor-binding site in the SPOUT-fold methyltransferases by computational docking of S-adenosylmethionine to three crystal structures. | BMC bioinformatics 20030101 |
Polyenylphosphatidylcholine corrects the alcohol-induced hepatic oxidative stress by restoring s-adenosylmethionine. | Alcohol and alcoholism (Oxford, Oxfordshire) 20030101 |
Alternative treatment modalities in human immunodeficiency virus/acquired immune deficiency syndrome. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030101 |
A novel function for the rTS gene. | Cancer biology & therapy 20030101 |
Differential transcriptional regulation of two distinct S-adenosylmethionine synthetase genes (SAM1 and SAM2) of Saccharomyces cerevisiae. | Nucleic acids research. Supplement (2001) 20030101 |
Homocystinuria due to cystathionine beta-synthase deficiency: novel biochemical findings and treatment efficacy. | Journal of inherited metabolic disease 20030101 |
S-adenosylmethionine (AdoMet) supplementation for treatment of chemotherapy-induced liver injury. | Anticancer research 20030101 |
Incorporating mechanistic data into risk assessment. | Toxicology 20021227 |
Deletion mutagenesis of human cystathionine beta-synthase. Impact on activity, oligomeric status, and S-adenosylmethionine regulation. | The Journal of biological chemistry 20021213 |
Osteoarthritis. Options for arthritis pain. | Newsweek 20021202 |
Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage. | Journal of neuroscience research 20021201 |
A double-blind, randomized parallel-group, efficacy and safety study of intramuscular S-adenosyl-L-methionine 1,4-butanedisulphonate (SAMe) versus imipramine in patients with major depressive disorder. | The international journal of neuropsychopharmacology 20021201 |
Pharmacodynamic studies on the central mode of action of S-adenosyl-L-methionine (SAMe) infusions in elderly subjects, utilizing EEG mapping and psychometry. | Journal of neural transmission (Vienna, Austria : 1996) 20021201 |
Structural basis of ICF-causing mutations in the methyltransferase domain of DNMT3B. | Protein engineering 20021201 |
Anthocyanin administration elevates plasma homocysteine in rats. | Journal of nutritional science and vitaminology 20021201 |
The [4Fe-4S](2+) cluster in reconstituted biotin synthase binds S-adenosyl-L-methionine. | Journal of the American Chemical Society 20021127 |
S-homoadenosyl-L-cysteine and S-homoadenosyl-L-homocysteine. Synthesis and binding studies of hon-hydrolyzed substrate analogues with S-adenosyl-L-homocysteine hydrolase. | The Journal of organic chemistry 20021115 |
Stabilization of S-adenosyl-L-methionine promoted by trehalose. | Biochimica et biophysica acta 20021114 |
Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine. | Hepatology (Baltimore, Md.) 20021101 |
[Meta-analysis of the efficacy of adenosylmethionine and oxaceprol in the treatment of osteoarthritis]. | Der Orthopade 20021101 |
The dual-specific active site of 7,8-diaminopelargonic acid synthase and the effect of the R391A mutation. | Biochemistry 20021022 |
Novel S-adenosyl-L-methionine:salicylic acid carboxyl methyltransferase, an enzyme responsible for biosynthesis of methyl salicylate and methyl benzoate, is not involved in floral scent production in snapdragon flowers. | Archives of biochemistry and biophysics 20021015 |
Cytoplasmic serine hydroxymethyltransferase mediates competition between folate-dependent deoxyribonucleotide and S-adenosylmethionine biosyntheses. | The Journal of biological chemistry 20021011 |
Alleviation of intrasteric inhibition by the pathogenic activation domain mutation, D444N, in human cystathionine beta-synthase. | Biochemistry 20021001 |
The production of hydrogen sulfide is regulated by testosterone and S-adenosyl-L-methionine in mouse brain. | Journal of neurochemistry 20021001 |
Biosynthetic studies on the tropane alkaloid hyoscyamine in Datura stramonium; hyoscyamine is stable to in vivo oxidation and is not derived from littorine via a vicinal interchange process. | Phytochemistry 20021001 |
Characterization of human soluble high and low activity catechol-O-methyltransferase catalyzed catechol estrogen methylation. | Pharmacogenetics 20021001 |
An essential role of s-adenosyl-L-methionine:L-methionine s-methyltransferase in selenium volatilization by plants. Methylation of selenomethionine to selenium-methyl-L-selenium- methionine, the precursor of volatile selenium. | Plant physiology 20021001 |
An anchoring role for FeS clusters: chelation of the amino acid moiety of S-adenosylmethionine to the unique iron site of the [4Fe-4S] cluster of pyruvate formate-lyase activating enzyme. | Journal of the American Chemical Society 20020925 |
A stereospecific colorimetric assay for (S,S)-adenosylmethionine quantification based on thiopurine methyltransferase-catalyzed thiol methylation. | Analytical biochemistry 20020915 |
Visualizing central effects of S-adenosyl-L-methionine (SAMe), a natural molecule with antidepressant properties, by pharmaco-EEG mapping. | The international journal of neuropsychopharmacology 20020901 |
S-adenosyl-methionine-induced apoptosis in PC12 cells. | Journal of neuroscience research 20020815 |
Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha. | The Journal of biological chemistry 20020809 |
Altered levels of S-adenosylmethionine and S-adenosylhomocysteine in the brains of L-isoaspartyl (D-Aspartyl) O-methyltransferase-deficient mice. | The Journal of biological chemistry 20020802 |
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801 |
Quantification of plasma S-adenosylmethionine and S-adenosylhomocysteine as their fluorescent 1,N(6)-etheno derivatives: an adaptation of previously described methodology. | Journal of pharmaceutical and biomedical analysis 20020731 |
Cystathionine beta-synthase is coordinately regulated with proliferation through a redox-sensitive mechanism in cultured human cells and Saccharomyces cerevisiae. | Journal of cellular physiology 20020701 |
Role of S-adenosyl-L-methionine in the treatment of alcoholic liver disease: introduction and summary of the symposium. | Alcohol (Fayetteville, N.Y.) 20020701 |
Role of abnormal methionine metabolism in alcoholic liver injury. | Alcohol (Fayetteville, N.Y.) 20020701 |
S-Adenosylmethionine revisited: its essential role in the regulation of liver function. | Alcohol (Fayetteville, N.Y.) 20020701 |
S-Adenosyl-L-methionine and alcoholic liver disease in animal models: implications for early intervention in human beings. | Alcohol (Fayetteville, N.Y.) 20020701 |
S-Adenosyl-L-methionine and mitochondrial reduced glutathione depletion in alcoholic liver disease. | Alcohol (Fayetteville, N.Y.) 20020701 |
S-Adenosylmethionine, cytokines, and alcoholic liver disease. | Alcohol (Fayetteville, N.Y.) 20020701 |
Chemoprevention of hepatocarcinogenesis: S-adenosyl-L-methionine. | Alcohol (Fayetteville, N.Y.) 20020701 |
S-adenosylmethionine is substrate for carrier mediated transport at the blood-brain barrier in vitro. | Brain research 20020628 |
S-adenosylmethionine conformations in solution and in protein complexes: conformational influences of the sulfonium group. | Biochemistry 20020618 |
High homocysteine and thrombosis without connective tissue disorders are associated with a novel class of cystathionine beta-synthase (CBS) mutations. | Human mutation 20020601 |
The effect of troglitazone on plasma homocysteine, hepatic and red blood cell S-adenosyl methionine, and S-adenosyl homocysteine and enzymes in homocysteine metabolism in Zucker rats. | Metabolism: clinical and experimental 20020601 |
Expression of recombinant human betaine: homocysteine S-methyltransferase for x-ray crystallographic studies and further characterization of interaction with S-adenosylmethionine. | Protein expression and purification 20020601 |
Probing the mysteries of lignin biosynthesis: the crystal structure of caffeic acid/5-hydroxyferulic acid 3/5-O-methyltransferase provides new insights. | The Plant cell 20020601 |
Recombinant alpha and beta subunits of M.AquI constitute an active DNA methyltransferase. | Journal of biochemistry and molecular biology 20020531 |
Brain hydrogen sulfide is severely decreased in Alzheimer's disease. | Biochemical and biophysical research communications 20020524 |
3-O-methyldobutamine, a major metabolite of dobutamine in humans. | Drug metabolism and disposition: the biological fate of chemicals 20020501 |
Diethanolamine induces hepatic choline deficiency in mice. | Toxicological sciences : an official journal of the Society of Toxicology 20020501 |
NO sensitizes rat hepatocytes to proliferation by modifying S-adenosylmethionine levels. | Gastroenterology 20020501 |
The Pneumocystis carinii drug target S-adenosyl-L-methionine:sterol C-24 methyl transferase has a unique substrate preference. | Molecular microbiology 20020501 |
Activation and induction of glycine N-methyltransferase by retinoids are tissue- and gender-specific. | Archives of biochemistry and biophysics 20020501 |
[Production of SAM by recombinant Pichia pastoris]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20020501 |
Reductive cleavage of S-adenosylmethionine by biotin synthase from Escherichia coli. | The Journal of biological chemistry 20020419 |
Enzymatic synthesis of [3'-O-methyl-(3)H]malvidin-3-glucoside from petunidin-3-glucoside. | Journal of agricultural and food chemistry 20020410 |
Trm7p catalyses the formation of two 2'-O-methylriboses in yeast tRNA anticodon loop. | The EMBO journal 20020402 |
LuxS: its role in central metabolism and the in vitro synthesis of 4-hydroxy-5-methyl-3(2H)-furanone. | Microbiology (Reading, England) 20020401 |
Hypermethylation of the cap structure of both yeast snRNAs and snoRNAs requires a conserved methyltransferase that is localized to the nucleolus. | Molecular cell 20020401 |
L-Homoserine: a novel excreted metabolic marker of hepatitis B abnormally produced in liver from methionine. | Medical hypotheses 20020401 |
S-adenosylhomocysteine, but not homocysteine, is toxic to yeast lacking cystathionine beta-synthase. | Molecular genetics and metabolism 20020401 |
Direct H atom abstraction from spore photoproduct C-6 initiates DNA repair in the reaction catalyzed by spore photoproduct lyase: evidence for a reversibly generated adenosyl radical intermediate. | Journal of the American Chemical Society 20020327 |
Electron-nuclear double resonance spectroscopic evidence that S-adenosylmethionine binds in contact with the catalytically active [4Fe-4S](+) cluster of pyruvate formate-lyase activating enzyme. | Journal of the American Chemical Society 20020327 |
Biochemistry: biosynthesis of an organofluorine molecule. | Nature 20020321 |
S-adenosyl-L-methionine prevents 5-HT(1A) receptors up-regulation induced by acute imipramine in the frontal cortex of the rat. | Neuroscience letters 20020315 |
Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy. | Neurology 20020312 |
Adenosine kinase deficiency is associated with developmental abnormalities and reduced transmethylation. | Plant physiology 20020301 |
Studies on the role of the metK gene product of Escherichia coli K-12. | Molecular microbiology 20020301 |
Tissue levels of S-adenosylhomocysteine in the rat kidney: effects of ischemia and homocysteine. | Biochemical pharmacology 20020215 |
Coordination of adenosylmethionine to a unique iron site of the [4Fe-4S] of pyruvate formate-lyase activating enzyme: a Mössbauer spectroscopic study. | Journal of the American Chemical Society 20020213 |
Metabolic engineering in yeast demonstrates that S-adenosylmethionine controls flux through the methylenetetrahydrofolate reductase reaction in vivo. | The Journal of biological chemistry 20020208 |
S-adenosylmethionine and methylthioadenosine are antiapoptotic in cultured rat hepatocytes but proapoptotic in human hepatoma cells. | Hepatology (Baltimore, Md.) 20020201 |
The N-terminal region of Arabidopsis cystathionine gamma-synthase plays an important regulatory role in methionine metabolism. | Plant physiology 20020201 |
High free-methionine and decreased lignin content result from a mutation in the Arabidopsis S-adenosyl-L-methionine synthetase 3 gene. | The Plant journal : for cell and molecular biology 20020201 |
An in vitro screening method for DNA cytosine-C5-methylase inhibitor. | Natural product letters 20020201 |
S-adenosylmethionine in treatment of cholestasis after total parenteral nutrition: laboratory investigation and clinical application. | Hepatobiliary & pancreatic diseases international : HBPD INT 20020201 |
Effects of S-adenosyl-L-methionine on lipid peroxidation and glutathione levels in rat brain slices exposed to reoxygenation after oxygen-glucose deprivation. | Neuroscience letters 20020125 |
Clinical nutrition: 3. The fuzzy boundary between nutrition and psychopharmacology. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020122 |
Obstetric cholestasis: outcome with active management. | European journal of obstetrics, gynecology, and reproductive biology 20020110 |
Molecular cloning and characterization of coclaurine N-methyltransferase from cultured cells of Coptis japonica. | The Journal of biological chemistry 20020104 |
Bacteriophage T4 Dam DNA-[N6-adenine]methyltransferase. Kinetic evidence for a catalytically essential conformational change in the ternary complex. | The Journal of biological chemistry 20020104 |
Domain alternation switches B(12)-dependent methionine synthase to the activation conformation. | Nature structural biology 20020101 |
Studies of methionine cycle intermediates (SAM, SAH), DNA methylation and the impact of folate deficiency on tumor numbers in Min mice. | Carcinogenesis 20020101 |
S-Adenosylmethionine: a control switch that regulates liver function. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020101 |
Constitutive overexpression of cystathionine gamma-synthase in Arabidopsis leads to accumulation of soluble methionine and S-methylmethionine. | Plant physiology 20020101 |
S-adenosyl-L-methionine (SAMe) for the treatment of acetaminophen toxicity in a dog. | Journal of the American Animal Hospital Association 20020101 |
[Metabolism pathways and use of heptral in chronic liver diseases]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20020101 |
[Aging of the pineal gland]. | Advances in gerontology = Uspekhi gerontologii 20020101 |
Liquid chromatographic determination of S-adenosyl-L-methionine in dietary supplement tablets. | Journal of AOAC International 20020101 |
[Isolation of S-adenosyl-L-methionine from an enriched Kluyveromyces lactis mutant, grown in whey media]. | Prikladnaia biokhimiia i mikrobiologiia 20020101 |
[Use of heptral in the complex treatment of pregnant women with cholestatic liver disease]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20020101 |
[The kinetic mechanism of phage T4 DNA-[N6-adenine]-methyltransferase]. | Molekuliarnaia biologiia 20020101 |
Scavengers protection of cells against ALA-based photodynamic therapy-induced damage. | Lasers in medical science 20020101 |
Kinetic characterization of transient free radical intermediates in reaction of lysine 2,3-aminomutase by EPR lineshape analysis. | Methods in enzymology 20020101 |
Structure, catalytic activity and evolutionary relationships of 1-aminocyclopropane-1-carboxylate synthase, the key enzyme of ethylene synthesis in higher plants. | Acta biochimica Polonica 20020101 |
S-adenosylmethionine and cAMP confer differential cytoprotection against bile acid-induced apoptosis in canine renal tubular cells and primary rat hepatocytes. | Veterinary therapeutics : research in applied veterinary medicine 20020101 |
Structure-based experimental confirmation of biochemical function to a methyltransferase, MJ0882, from hyperthermophile Methanococcus jannaschii. | Journal of structural and functional genomics 20020101 |
Influence of SAMe on the modifications of brain polyamine levels in an animal model of depression. | Neuroreport 20011221 |
Impact of extracellular folate levels on global gene expression. | Molecular pharmacology 20011201 |
The effect of high doses of folic acid on the overexpression of ornithine decarboxylase and S-adenosylmethionine content in human colon adenomatous polyps. | Annals of the New York Academy of Sciences 20011201 |
Design of allele-specific protein methyltransferase inhibitors. | Journal of the American Chemical Society 20011128 |
Characterization of AloI, a restriction-modification system of a new type. | Journal of molecular biology 20011123 |
Crystal structure of a protein repair methyltransferase from Pyrococcus furiosus with its L-isoaspartyl peptide substrate. | Journal of molecular biology 20011109 |
S-adenosyl-L-methionine N-ole-1-oyltaurate: pharmacokinetic of the orally administered salt in rats. | International journal of pharmaceutics 20011106 |
Dietary betaine accumulates in the liver and intestinal tissue and stabilizes the intestinal epithelial structure in healthy and coccidia-infected broiler chicks. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20011101 |
Anti-aging products, Part I. Can supplements rewind our body clocks? | Harvard women's health watch 20011101 |
Glutamate 47 in 1-aminocyclopropane-1-carboxylate synthase is a major specificity determinant. | Biochemistry 20011016 |
Reversed-phase high-performance liquid chromatography procedure for the simultaneous determination of S-adenosyl-L-methionine and S-adenosyl-L-homocysteine in mouse liver and the effect of methionine on their concentrations. | Journal of chromatography. B, Biomedical sciences and applications 20011005 |
Methylation is involved in the Ustilago maydis mating response. | Fungal genetics and biology : FG & B 20011001 |
COMT genotype, micronutrients in the folate metabolic pathway and breast cancer risk. | Carcinogenesis 20011001 |
Adenosylmethionine as a source of 5'-deoxyadenosyl radicals. | Current opinion in chemical biology 20011001 |
Enzymology of carbon-sulfur bond formation. | Current opinion in chemical biology 20011001 |
Getting the adrenaline going: crystal structure of the adrenaline-synthesizing enzyme PNMT. | Structure (London, England : 1993) 20011001 |
Determination of thiopurine methyltransferase activity in human erythrocytes by high-performance liquid chromatography: comparison with the radiochemical method. | Therapeutic drug monitoring 20011001 |
Nutritional regulation of homocysteine: effects of drugs. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20011001 |
DNA cleavage by type III restriction-modification enzyme EcoP15I is independent of spacer distance between two head to head oriented recognition sites. | Journal of molecular biology 20010928 |
Regulation of human cystathionine beta-synthase by S-adenosyl-L-methionine: evidence for two catalytically active conformations involving an autoinhibitory domain in the C-terminal region. | Biochemistry 20010904 |
Increasing levels of dietary homocystine with carotid endarterectomy produced proportionate increases in plasma homocysteine and intimal hyperplasia. | Atherosclerosis 20010901 |
L-dopa upregulates the expression and activities of methionine adenosyl transferase and catechol-O-methyltransferase. | Experimental neurology 20010901 |
Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathy. | Metabolism: clinical and experimental 20010901 |
Effects of S-adenosyl-L-methionine on liver damage in experimental obstructive jaundice. | The Kaohsiung journal of medical sciences 20010901 |
PRMT5 (Janus kinase-binding protein 1) catalyzes the formation of symmetric dimethylarginine residues in proteins. | The Journal of biological chemistry 20010831 |
Methylation of histone H4 at arginine 3 facilitating transcriptional activation by nuclear hormone receptor. | Science (New York, N.Y.) 20010803 |
Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia. | Journal of inherited metabolic disease 20010801 |
Decrease of methionine and S-adenosylmethionine and increase of homocysteine in treated patients with Parkinson's disease. | Neuroscience letters 20010727 |
Characterization of an allylic analogue of the 5'-deoxyadenosyl radical: an intermediate in the reaction of lysine 2,3-aminomutase. | Biochemistry 20010703 |
Diadenosine phosphates and S-adenosylmethionine: novel boron binding biomolecules detected by capillary electrophoresis. | Biochimica et biophysica acta 20010702 |
Homocysteine metabolism in children with Down syndrome: in vitro modulation. | American journal of human genetics 20010701 |
Wy-14,643-induced hypomethylation of the c-myc gene in mouse liver. | Toxicological sciences : an official journal of the Society of Toxicology 20010701 |
Roles of homocysteine in cell metabolism: old and new functions. | European journal of biochemistry 20010701 |
The LuxS family of bacterial autoinducers: biosynthesis of a novel quorum-sensing signal molecule. | Molecular microbiology 20010701 |
S-adenosyl-L-methionine is required for DNA cleavage by type III restriction enzymes. | Journal of molecular biology 20010629 |
The mechanism of DNA cytosine-5 methylation. Kinetic and mutational dissection of Hhai methyltransferase. | The Journal of biological chemistry 20010615 |
A new caffeine biosynthetic pathway in tea leaves: utilisation of adenosine released from the S-adenosyl-L-methionine cycle. | FEBS letters 20010615 |
Activation of class III ribonucleotide reductase from E. coli. The electron transfer from the iron-sulfur center to S-adenosylmethionine. | Biochemistry 20010612 |
Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice. | Circulation research 20010608 |
Blood determinations of S-adenosylmethionine, S-adenosylhomocysteine, and homocysteine: correlations with diet. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010601 |
Effect of vitamin B6 deficiency on the synthesis and accumulation of S-adenosylhomocysteine and S-adenosylmethionine in rat tissues. | Journal of nutritional science and vitaminology 20010601 |
Inhibition of liver methionine adenosyltransferase gene expression by 3-methylcolanthrene: protective effect of S-adenosylmethionine. | Biochemical pharmacology 20010501 |
Impaired homocysteine metabolism and atherothrombotic disease. | Laboratory investigation; a journal of technical methods and pathology 20010501 |
How is the liver primed or sensitized for alcoholic liver disease? | Alcoholism, clinical and experimental research 20010501 |
Ca2+-antagonists inhibit the N-methyltransferase-dependent synthesis of phosphatidylcholine in the heart. | Molecular and cellular biochemistry 20010501 |
Metabolic labeling of prenyl and carboxyl-methyl groups. | Current protocols in cell biology 20010501 |
S-Adenosyl-L-methionine-dependent O-methylation of 2-hydroxy-3-alkylpyrazine in wine grapes: a putative final step of methoxypyrazine biosynthesis. | Bioscience, biotechnology, and biochemistry 20010401 |
Activation of class III ribonucleotide reductase by thioredoxin. | The Journal of biological chemistry 20010330 |
Activation of class III ribonucleotide reductase by flavodoxin: a protein radical-driven electron transfer to the iron-sulfur center. | Biochemistry 20010327 |
Role of adenosine kinase in Saccharomyces cerevisiae: identification of the ADO1 gene and study of the mutant phenotypes. | Yeast (Chichester, England) 20010315 |
The dynamics of myogenin site-specific demethylation is strongly correlated with its expression and with muscle differentiation. | The Journal of biological chemistry 20010309 |
COMT-dependent protection of dopaminergic neurons by methionine, dimethionine and S-adenosylmethionine (SAM) against L-dopa toxicity in vitro. | Brain research 20010302 |
Novel methylated triterpenoids of the gammacerane series from the nitrogen-fixing bacterium Bradyrhizobium japonicum USDA 110. | European journal of biochemistry 20010301 |
Adenosylmethionine-dependent iron-sulfur enzymes: versatile clusters in a radical new role. | Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20010301 |
5'-Methylthioadenosine administration prevents lipid peroxidation and fibrogenesis induced in rat liver by carbon-tetrachloride intoxication. | Journal of hepatology 20010301 |
S-adenosylmethionine protects post-ischemic mitochondrial injury in rat liver. | Journal of hepatology 20010301 |
Crystal structure of threonine synthase from Arabidopsis thaliana. | Protein science : a publication of the Protein Society 20010301 |
A Taq attack displaces bases. | Nature structural biology 20010201 |
Structure of the N6-adenine DNA methyltransferase M.TaqI in complex with DNA and a cofactor analog. | Nature structural biology 20010201 |
Role of promoter methylation in increased methionine adenosyltransferase 2A expression in human liver cancer. | American journal of physiology. Gastrointestinal and liver physiology 20010201 |
Effect of tauroursodeoxycholate and S-adenosyl-L-methionine on 17beta-estradiol glucuronide-induced cholestasis. | Journal of hepatology 20010201 |
Polyamine regulation of ornithine decarboxylase and its antizyme in intestinal epithelial cells. | American journal of physiology. Gastrointestinal and liver physiology 20010101 |
Disturbed ratio of erythrocyte and plasma S-adenosylmethionine/S-adenosylhomocysteine in peripheral arterial occlusive disease. | Atherosclerosis 20010101 |
Synthesis and characterization of an immobilized phenylethanolamine N-methyltransferase liquid chromatographic stationary phase. | Analytical biochemistry 20010101 |
Erythroid differentiation and regulatory gene expression are modulated by adenosine derivatives interfering with S-adenosylmethionine metabolic pathway. | Journal of cellular biochemistry 20010101 |
Role of S-adenosyl-L-methionine in potentiating cadmium mobilization by diethylenetriamine penta acetic acid in mice. | Cytobios 20010101 |
Liver diseases by alcohol and hepatitis C: early detection and new insights in pathogenesis lead to improved treatment. | The American journal on addictions 20010101 |
Radical mechanisms of enzymatic catalysis. | Annual review of biochemistry 20010101 |
Radical mechanisms of S-adenosylmethionine-dependent enzymes. | Advances in protein chemistry 20010101 |
Interventions for treating cholestasis in pregnancy. | The Cochrane database of systematic reviews 20010101 |
S-adenosyl-L-methionine for alcoholic liver diseases. | The Cochrane database of systematic reviews 20010101 |
The role of radicals in enzymatic processes. | Chemical record (New York, N.Y.) 20010101 |
Escherichia coli LipA is a lipoyl synthase: in vitro biosynthesis of lipoylated pyruvate dehydrogenase complex from octanoyl-acyl carrier protein. | Biochemistry 20001212 |
Effect of different doses of S-adenosyl-L-methionine on paracetamol hepatotoxicity in a mouse model. | Methods and findings in experimental and clinical pharmacology 20001201 |
Farnesyl-L-cysteine analogs block SAM-induced Parkinson's disease-like symptoms in rats. | Pharmacology, biochemistry, and behavior 20000801 |
Homocysteine. | The international journal of biochemistry & cell biology 20000401 |
Molecular biology of 5,10-methylenetetrahydrofolate reductase. | Journal of nephrology 20000101 |
Open study of the catechol-O-methyltransferase inhibitor tolcapone in major depressive disorder. | Journal of clinical psychopharmacology 19990801 |
Differential effect of thioacetamide on hepatic methionine adenosyltransferase expression in the rat. | Hepatology (Baltimore, Md.) 19990501 |
One-methyl group metabolism in non-ketotic hyperglycinaemia: mildly elevated cerebrospinal fluid homocysteine levels. | Journal of inherited metabolic disease 19981201 |
Purification, characterization, and cloning of an S-adenosylmethionine-dependent 3-amino-3-carboxypropyltransferase in nocardicin biosynthesis. | The Journal of biological chemistry 19981113 |
Demyelination and single-carbon transfer pathway metabolites during the treatment of acute lymphoblastic leukemia: CSF studies. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 19980401 |
Effects of some thiol chelators on enzymatic activities in blood, liver and kidneys of acute arsenic (III) exposed mice. | Biomedical and environmental sciences : BES 19980301 |
[Morphological changes induced by valproate and its administration concomitant with folinic acid or S-adenosylmethionine in pregnant rats]. | Nutricion hospitalaria 19980101 |
Effects of S-adenosylmethionine on lipid peroxidation and liver fibrogenesis in carbon tetrachloride-induced cirrhosis. | Journal of hepatology 19960801 |
S-Adenosylmethionine and methylation. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19960301 |
Inhibition of human thiopurine methyltransferase by furosemide, bendroflumethiazide and trichlormethiazide. | European journal of clinical pharmacology 19960101 |
Ultrastructural features of danazol-induced cholestasis: a case study. | Ultrastructural pathology 19960101 |
Enzymatic methylation of arsenic compounds: assay, partial purification, and properties of arsenite methyltransferase and monomethylarsonic acid methyltransferase of rabbit liver. | Chemical research in toxicology 19951201 |
Arrangement of catalytic sites in the multifunctional enzyme enniatin synthetase. | European journal of biochemistry 19950515 |
Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme. | Biochemistry 19950404 |
The clinical potential of ademetionine (S-adenosylmethionine) in neurological disorders. | Drugs 19940801 |
Correlation between S-adenosyl-L-methionine content and production of c-myc, c-Ha-ras, and c-Ki-ras mRNA transcripts in the early stages of rat liver carcinogenesis. | Cancer letters 19940429 |
Adenosylmethionine-dependent synthesis of the glycyl radical in pyruvate formate-lyase by abstraction of the glycine C-2 pro-S hydrogen atom. Studies of [2H]glycine-substituted enzyme and peptides homologous to the glycine 734 site. | The Journal of biological chemistry 19940429 |
Differential kinetic properties of L-2-amino-4-methylthio-cis-but-3-enoic acid, a methionine analog inhibitor of S-adenosylmethionine synthetase. | Biochimica et biophysica acta 19930903 |
S-adenosyl-L-methionine decreases motor activity in the rat: similarity to Parkinson's disease-like symptoms. | Behavioral and neural biology 19930501 |
Resolution of danazol-induced cholestasis with S-adenosylmethionine. | Postgraduate medical journal 19930301 |
Parkinson's disease-like effects of S-adenosyl-L-methionine: effects of L-dopa. | Pharmacology, biochemistry, and behavior 19921001 |
Reversal of extrahepatic membrane cholesterol deposition in patients with chronic liver diseases by S-adenosyl-L-methionine. | Clinical science (London, England : 1979) 19920901 |
S-adenosylmethionine: studies on chemical and enzymatic synthesis. | Biotechnology and applied biochemistry 19870201 |
Open trial of S-adenosylmethionine for treatment of depression. | The American journal of psychiatry 19840301 |
Brain methylation and epileptogenesis: the case of methionine sulfoximine. | Annals of neurology 19840101 |
Modulation by S-adenosyl-L-methionine of hepatic Na+,K+-ATPase, membrane fluidity, and bile flow in rats with ethinyl estradiol-induced cholestasis. | Hepatology (Baltimore, Md.) 19830101 |
Estrogen-induced cholestasis: clues to pathogenesis and treatment. | Hepatology (Baltimore, Md.) 19830101 |
Ethynylestradiol-induced impairment of bile secretion in the rat: protective effects of S-adenosyl-L-methionine and its implication in estrogen metabolism. | Gastroenterology 19810101 |
Tremor induced by S-adenosyl-L-methionine: possible relation to L-dopa effects. | The Journal of pharmacy and pharmacology 19781201 |
Letter: General base catalysis in nucleophilic attack at sp3 carbon of methylase model compounds. | Journal of the American Chemical Society 19760218 |
Methionine metabolism in mammals: synthesis of S-adenosylhomocysteine in rat tissues. | Archives of biochemistry and biophysics 19731101 |