Home Halogens 5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide

5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide

CAS No.:
366789-02-8
Catalog Number:
AG0035KL
Molecular Formula:
C19H18ClN3O5S
Molecular Weight:
435.8813
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$19
- +
5g
98%
In Stock USA
United States
$57
- +
10g
98%
In Stock USA
United States
$88
- +
25g
98%
In Stock USA
United States
$175
- +
100g
98%
In Stock USA
United States
$563
- +
Product Description
Catalog Number:
AG0035KL
Chemical Name:
5-chloro-N-{[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl}thiophene-2-carboxamide
CAS Number:
366789-02-8
Molecular Formula:
C19H18ClN3O5S
Molecular Weight:
435.8813
MDL Number:
MFCD11974010
IUPAC Name:
5-chloro-N-[[(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl]methyl]thiophene-2-carboxamide
InChI:
InChI=1S/C19H18ClN3O5S/c20-16-6-5-15(29-16)18(25)21-9-14-10-23(19(26)28-14)13-3-1-12(2-4-13)22-7-8-27-11-17(22)24/h1-6,14H,7-11H2,(H,21,25)/t14-/m0/s1
InChI Key:
KGFYHTZWPPHNLQ-AWEZNQCLSA-N
SMILES:
O=C1O[C@H](CN1c1ccc(cc1)N1CCOCC1=O)CNC(=O)c1ccc(s1)Cl
UNII:
9NDF7JZ4M3
Properties
Complexity:
645  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
435.066g/mol
Formal Charge:
0
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
435.879g/mol
Monoisotopic Mass:
435.066g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
116A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.5  
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[Haemostasis and antithrombotic drugs: pharmacology and novel therapeutic approaches]. Hamostaseologie 20060501
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20060401
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Oral, direct Factor Xa inhibition with BAY 59-7939 for the prevention of venous thromboembolism after total hip replacement. Journal of thrombosis and haemostasis : JTH 20060101
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Safety, pharmacodynamics, and pharmacokinetics of single doses of BAY 59-7939, an oral, direct factor Xa inhibitor. Clinical pharmacology and therapeutics 20051001
Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. Journal of medicinal chemistry 20050922
Pharmacokinetics of BAY 59-7939--an oral, direct Factor Xa inhibitor--in rats and dogs. Xenobiotica; the fate of foreign compounds in biological systems 20050901
New antithrombotics in the prevention of thromboembolic disease. European journal of internal medicine 20050801
In vitro and in vivo studies of the novel antithrombotic agent BAY 59-7939--an oral, direct Factor Xa inhibitor. Journal of thrombosis and haemostasis : JTH 20050301
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