Rapamycin
| Title | Journal |
|---|---|
| Autophagy plays a pro-survival role against methamphetamine-induced apoptosis in H9C2 cells. | Toxicology letters 20180915 |
| Effect of cyclosporine, tacrolimus and sirolimus on cellular senescence in renal epithelial cells. | Toxicology in vitro : an international journal published in association with BIBRA 20180401 |
| Inhibition of autophagy enhances Hydroquinone-induced TK6 cell death. | Toxicology in vitro : an international journal published in association with BIBRA 20170601 |
| Effect of exogenous TGF-β1 on the cadmium-induced nephrotoxicity by inhibiting apoptosis of proximal tubular cells through PI3K-AKT-mTOR signaling pathway. | Chemico-biological interactions 20170501 |
| Somatic Mutations in TSC1 and TSC2 Cause Focal Cortical Dysplasia. | American journal of human genetics 20170302 |
| mTOR inhibition by rapamycin protects against deltamethrin-induced apoptosis in PC12 Cells. | Environmental toxicology 20170101 |
| Phosphoramide mustard induces autophagy markers and mTOR inhibition prevents follicle loss due to phosphoramide mustard exposure. | Reproductive toxicology (Elmsford, N.Y.) 20170101 |
| CWF-145, a novel synthetic quinolone derivative exerts potent antimitotic activity against human prostate cancer: Rapamycin enhances antimitotic drug-induced apoptosis through the inhibition of Akt/mTOR pathway. | Chemico-biological interactions 20161225 |
| Basal autophagy protects cardiomyocytes from doxorubicin-induced toxicity. | Toxicology 20160831 |
| Knockdown of NogoA prevents MPP+‑induced neurotoxicity in PC12 cells via the mTOR/STAT3 signaling pathway. | Molecular medicine reports 20160201 |
| Impairment of the autophagic flux in astrocytes intoxicated by trimethyltin. | Neurotoxicology 20160101 |
| Cabozantinib versus Everolimus in Advanced Renal-Cell Carcinoma. | The New England journal of medicine 20151105 |
| The role of mTOR during cisplatin treatment in an in vitro and ex vivo model of cervical cancer. | Toxicology 20150901 |
| Cannabidiol, a Cannabis sativa constituent, inhibits cocaine-induced seizures in mice: Possible role of the mTOR pathway and reduction in glutamate release. | Neurotoxicology 20150901 |
| Activation of Autophagic Flux against Xenoestrogen Bisphenol-A-induced Hippocampal Neurodegeneration via AMP kinase (AMPK)/Mammalian Target of Rapamycin (mTOR) Pathways. | The Journal of biological chemistry 20150821 |
| The mechanism of synergistic effects of arsenic trioxide and rapamycin in acute myeloid leukemia cell lines lacking typical t(15;17) translocation. | International journal of hematology 20150701 |
| A comprehensively characterized large panel of head and neck cancer patient-derived xenografts identifies the mTOR inhibitor everolimus as potential new treatment option. | International journal of cancer 20150615 |
| Synergistic effect of JQ1 and rapamycin for treatment of human osteosarcoma. | International journal of cancer 20150501 |
| Key role of phosphodiesterase 4A (PDE4A) in autophagy triggered by yessotoxin. | Toxicology 20150302 |
| mTOR inhibition improves immune function in the elderly. | Science translational medicine 20141224 |
| The immunosuppressant tributyltin oxide blocks the mTOR pathway, like rapamycin, albeit by a different mechanism. | Journal of applied toxicology : JAT 20141201 |
| A highly potent and selective Vps34 inhibitor alters vesicle trafficking and autophagy. | Nature chemical biology 20141201 |
| The bromodomain and extra-terminal inhibitor CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors. | Cell death & disease 20141001 |
| P-glycoprotein, CYP3A, and plasma carboxylesterase determine brain and blood disposition of the mTOR Inhibitor everolimus (Afinitor) in mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20140615 |
| A phase Ib trial of LY2584702 tosylate, a p70 S6 inhibitor, in combination with erlotinib or everolimus in patients with solid tumours. | European journal of cancer (Oxford, England : 1990) 20140301 |
| Resveratrol prevents rapamycin-induced upregulation of autophagy and selectively induces apoptosis in TSC2-deficient cells. | Cell cycle (Georgetown, Tex.) 20140201 |
| Dominant-activating germline mutations in the gene encoding the PI(3)K catalytic subunit p110δ result in T cell senescence and human immunodeficiency. | Nature immunology 20140101 |
| Conversion to sirolimus ameliorates cyclosporine-induced nephropathy in the rat: focus on serum, urine, gene, and protein renal expression biomarkers. | BioMed research international 20140101 |
| Rapamycin attenuated cardiac hypertrophy induced by isoproterenol and maintained energy homeostasis via inhibiting NF-κB activation. | Mediators of inflammation 20140101 |
| Autophagy maturation associated with CD38-mediated regulation of lysosome function in mouse glomerular podocytes. | Journal of cellular and molecular medicine 20131201 |
| Activation of autophagy rescues amiodarone-induced apoptosis of lung epithelial cells and pulmonary toxicity in rats. | Toxicological sciences : an official journal of the Society of Toxicology 20131101 |
| PI3Kδ inhibition augments the efficacy of rapamycin in suppressing proliferation of Epstein-Barr virus (EBV)+ B cell lymphomas. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20130801 |
| Synergistic interactions between sorafenib and everolimus in pancreatic cancer xenografts in mice. | Cancer chemotherapy and pharmacology 20130501 |
| A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery. | The Biochemical journal 20130415 |
| Inhibition of rapamycin-induced Akt phosphorylation by cotylenin A correlates with their synergistic growth inhibition of cancer cells. | International journal of oncology 20130201 |
| Efficacy of RNA polymerase II inhibitors in targeting dormant leukaemia cells. | BMC pharmacology & toxicology 20130101 |
| Enhancement of autophagy by simvastatin through inhibition of Rac1-mTOR signaling pathway in coronary arterial myocytes. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20130101 |
| Arsenic trioxide overcomes rapamycin-induced feedback activation of AKT and ERK signaling to enhance the anti-tumor effects in breast cancer. | PloS one 20130101 |
| Involvement of autophagy in the pharmacological effects of the mTOR inhibitor everolimus in acute kidney injury. | European journal of pharmacology 20121205 |
| A phase I study of temozolomide and everolimus (RAD001) in patients with newly diagnosed and progressive glioblastoma either receiving or not receiving enzyme-inducing anticonvulsants: an NCIC CTG study. | Investigational new drugs 20121201 |
| A phase II trial of temsirolimus in second-line metastatic urothelial cancer. | Medical oncology (Northwood, London, England) 20121201 |
| Rapamycin treatment inhibits CHO cell death in a serum-free suspension culture by autophagy induction. | Biotechnology and bioengineering 20121201 |
| Autophagy is a cell self-protective mechanism against arsenic-induced cell transformation. | Toxicological sciences : an official journal of the Society of Toxicology 20121201 |
| The isoprenoid perillyl alcohol inhibits telomerase activity in prostate cancer cells. | Biochimie 20121201 |
| Acute and sustained effects of a metabotropic glutamate 5 receptor antagonist in the novelty-suppressed feeding test. | Behavioural brain research 20121201 |
| Enteric-delivered rapamycin enhances resistance of aged mice to pneumococcal pneumonia through reduced cellular senescence. | Experimental gerontology 20121201 |
| The expression of URGCP gene in prostate cancer cell lines: correlation with rapamycin. | Molecular biology reports 20121201 |
| Potential anti-aging agents suppress the level of constitutive mTOR- and DNA damage- signaling. | Aging 20121201 |
| Efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 in a preclinical model of adrenocortical carcinoma. | Molecular and cellular endocrinology 20121125 |
| Sirolimus solid self-microemulsifying pellets: formulation development, characterization and bioavailability evaluation. | International journal of pharmaceutics 20121115 |
| Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. | Bioorganic & medicinal chemistry 20121115 |
| Randomized comparison of the Nobori biolimus A9-eluting stent with the sirolimus-eluting stent in patients with stenosis in native coronary arteries. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121101 |
| Phase II trial of temsirolimus in patients with metastatic breast cancer. | Breast cancer research and treatment 20121101 |
| Remarkable inhibition of mTOR signaling by the combination of rapamycin and 1,4-phenylenebis(methylene)selenocyanate in human prostate cancer cells. | International journal of cancer 20121101 |
| Influence of sirolimus-loaded nanoparticles on physiological functions of native human polymorphonuclear neutrophils. | Nanomedicine : nanotechnology, biology, and medicine 20121101 |
| Role of autophagy inhibitors and inducers in modulating the toxicity of trimethyltin in neuronal cell cultures. | Journal of neural transmission (Vienna, Austria : 1996) 20121101 |
| Rapamycin enhances dimethyl sulfoxide-mediated growth arrest in human myelogenous leukemia cells. | Leukemia & lymphoma 20121101 |
| Acetylation of histone H3 prevents resistance development caused by chronic mTOR inhibition in renal cell carcinoma cells. | Cancer letters 20121101 |
| Assessment of an asymmetrical coating stent with sirolimus released from ablumial matrix in porcine model. | Clinical research in cardiology : official journal of the German Cardiac Society 20121101 |
| Anti-thymocyte globulin (thymoglobulin), tacrolimus, and sirolimus as acute graft-versus-host disease prophylaxis for unrelated hematopoietic stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20121101 |
| Rapamycin-mediated suppression of renal cyst expansion in del34 Pkd1-/- mutant mouse embryos: an investigation of the feasibility of renal cyst prevention in the foetus. | Nephrology (Carlton, Vic.) 20121101 |
| UV-visible spectroscopy as an alternative to liquid chromatography for determination of everolimus in surfactant-containing dissolution media: a useful approach based on solid-phase extraction. | Journal of pharmaceutical and biomedical analysis 20121101 |
| Proliferation signal inhibitors in the treatment of lupus nephritis: preliminary experience. | Nephrology (Carlton, Vic.) 20121101 |
| Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growth. | Carcinogenesis 20121101 |
| Autophagy-dependent and -independent involvement of AMP-activated protein kinase in 6-hydroxydopamine toxicity to SH-SY5Y neuroblastoma cells. | Biochimica et biophysica acta 20121101 |
| A dose escalation trial for the combination of erlotinib and sirolimus for recurrent malignant gliomas. | Journal of neuro-oncology 20121101 |
| NVP-BEZ235 alone and in combination in mantle cell lymphoma: an effective therapeutic strategy. | Expert opinion on investigational drugs 20121101 |
| Autophagy modulators sensitize prostate epithelial cancer cell lines to TNF-alpha-dependent apoptosis. | Apoptosis : an international journal on programmed cell death 20121101 |
| Towards excellence in revascularization for left main coronary artery disease. | Current opinion in cardiology 20121101 |
| Everolimus synergizes with gefitinib in non-small-cell lung cancer cell lines resistant to epidermal growth factor receptor tyrosine kinase inhibitors. | Cancer chemotherapy and pharmacology 20121101 |
| A drug safety evaluation of everolimus in kidney transplantation. | Expert opinion on drug safety 20121101 |
| Endothelial progenitor cell response to antiproliferative drug exposure. | Atherosclerosis 20121101 |
| Phosphatidylinositol 3-kinase/AKT/mammalian target of rapamycin pathway inhibition: a breakthrough in the management of luminal (ER+/HER2-) breast cancers? | Current opinion in oncology 20121101 |
| Prolonged response using gefitinib followed by sirolimus for advanced cutaneous squamous cell carcinoma. | Journal of the American Academy of Dermatology 20121101 |
| Topical sirolimus for oral pemphigus vulgaris: 3 unresponsive cases. | Journal of the American Academy of Dermatology 20121101 |
| Hemodialysis does not affect everolimus pharmacokinetics: two cases of patients with metastatic renal cell cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20121101 |
| Bioanalytical method validation of rapamycin in ocular matrix by QTRAP LC-MS/MS: application to rabbit anterior tissue distribution by topical administration of rapamycin nanomicellar formulation. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20121101 |
| Chronic inhibition of mammalian target of rapamycin by rapamycin modulates cognitive and non-cognitive components of behavior throughout lifespan in mice. | Neuroscience 20121025 |
| Targeting JAK1/2 and mTOR in murine xenograft models of Ph-like acute lymphoblastic leukemia. | Blood 20121025 |
| Mammalian target of rapamycin signaling is a key regulator of the transit-amplifying progenitor pool in the adult and aging forebrain. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20121024 |
| Stent thrombosis and major clinical events at 3 years after zotarolimus-eluting or sirolimus-eluting coronary stent implantation: a randomised, multicentre, open-label, controlled trial. | Lancet (London, England) 20121020 |
| Sirolimus and skin-cancer prevention in kidney transplantation. | The New England journal of medicine 20121018 |
| Clinical and histopathologic characteristics of rash in cancer patients treated with mammalian target of rapamycin inhibitors. | Cancer 20121015 |
| Phase I study of the antiangiogenic antibody bevacizumab and the mTOR/hypoxia-inducible factor inhibitor temsirolimus combined with liposomal doxorubicin: tolerance and biological activity. | Clinical cancer research : an official journal of the American Association for Cancer Research 20121015 |
| A comprehensive review of everolimus clinical reports: a new mammalian target of rapamycin inhibitor. | Transplantation 20121015 |
| Genome sequencing identifies a basis for everolimus sensitivity. | Science (New York, N.Y.) 20121012 |
| Mammalian target of rapamycin regulates neutrophil extracellular trap formation via induction of hypoxia-inducible factor 1 α. | Blood 20121011 |
| Pharmacokinetic study of 3-in-1 poly(ethylene glycol)-block-poly(D, L-lactic acid) micelles carrying paclitaxel, 17-allylamino-17-demethoxygeldanamycin, and rapamycin. | Journal of controlled release : official journal of the Controlled Release Society 20121010 |
| A new strategy for discontinuation of dual antiplatelet therapy: the RESET Trial (REal Safety and Efficacy of 3-month dual antiplatelet Therapy following Endeavor zotarolimus-eluting stent implantation). | Journal of the American College of Cardiology 20121009 |
| Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM). | Science translational medicine 20121003 |
| Sustained clinical effectiveness and favorable safety profile of topical sirolimus for tuberous sclerosis - associated facial angiofibroma. | Journal of the European Academy of Dermatology and Venereology : JEADV 20121001 |
| Phase I study of temsirolimus in combination with EKB-569 in patients with advanced solid tumors. | Investigational new drugs 20121001 |
| Sirolimus- versus paclitaxel-eluting stents for coronary bifurcations intervention: a meta-analysis of five clinical trials. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121001 |
| The XIENCE nano everolimus eluting coronary stent system for the treatment of small coronary arteries: the SPIRIT Small Vessel trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20121001 |
| Rapamycin blocks hepatoblastoma growth in vitro and in vivo implicating new treatment options in high-risk patients. | European journal of cancer (Oxford, England : 1990) 20121001 |
| The impact of prophylactic antiviral agents and statin administration on graft longevity in kidney allograft recipients. | Immunopharmacology and immunotoxicology 20121001 |
| Phase II study of everolimus in patients with locally advanced or metastatic transitional cell carcinoma of the urothelial tract: clinical activity, molecular response, and biomarkers. | Annals of oncology : official journal of the European Society for Medical Oncology 20121001 |
| Effects of FTY720 and rapamycin on inflammation in taurocholate-induced acute pancreatitis in the rat. | Pancreas 20121001 |
| Overcoming acquired resistance to letrozole by targeting the PI3K/AKT/mTOR pathway in breast cancer cell clones. | Cancer letters 20121001 |
| Antitumor effect of the mTOR inhibitor everolimus in combination with trastuzumab on human breast cancer stem cells in vitro and in vivo. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20121001 |
| Neoadjuvant therapy of renal cell carcinoma: a novel treatment option in the era of targeted therapy? | International journal of urology : official journal of the Japanese Urological Association 20121001 |
| Tolerability and pharmacokinetics of intravitreal sirolimus. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20121001 |
| Novel agents in Hodgkin lymphoma. | Current oncology reports 20121001 |
| NEX-TRAP, a novel method for in vivo analysis of nuclear export of proteins. | Traffic (Copenhagen, Denmark) 20121001 |
| Combined blockade of signalling pathways shows marked anti-tumour potential in phaeochromocytoma cell lines. | Journal of molecular endocrinology 20121001 |
| Phase I study of pasireotide (SOM 230) and everolimus (RAD001) in advanced neuroendocrine tumors. | Endocrine-related cancer 20121001 |
| Impact of the first-generation drug-eluting stent implantation on periprocedural myocardial injury in patients with stable angina pectoris. | Journal of cardiology 20121001 |
| Guanosine produces an antidepressant-like effect through the modulation of NMDA receptors, nitric oxide-cGMP and PI3K/mTOR pathways. | Behavioural brain research 20121001 |
| Macroautophagy can press a brake on presynaptic neurotransmission. | Autophagy 20121001 |
| Ischemic postconditioning during reperfusion attenuates intestinal injury and mucosal cell apoptosis by inhibiting JAK/STAT signaling activation. | Shock (Augusta, Ga.) 20121001 |
| Effects of sotrastaurin, mycophenolic acid and everolimus on human B-lymphocyte function and activation. | Transplant international : official journal of the European Society for Organ Transplantation 20121001 |
| Serial change and its determinants of residual plaque characteristics under sirolimus-eluting stent: a coronary angioscopic study. | Journal of cardiology 20121001 |
| Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells. | Molecular endocrinology (Baltimore, Md.) 20121001 |
| Disrupting the mTOR signaling network as a potential strategy for the enhancement of cancer radiotherapy. | Current cancer drug targets 20121001 |
| IL-22 induced cell proliferation is regulated by PI3K/Akt/mTOR signaling cascade. | Cytokine 20121001 |
| Everolimus for advanced pancreatic neuroendocrine tumours: a subgroup analysis evaluating Japanese patients in the RADIANT-3 trial. | Japanese journal of clinical oncology 20121001 |
| Association of sirolimus adverse effects with m-TOR, p70S6K or Raptor polymorphisms in kidney transplant recipients. | Pharmacogenetics and genomics 20121001 |
| Everolimus for the treatment of pancreatic neuroendocrine tumors. | Expert opinion on pharmacotherapy 20121001 |
| FLT-PET is superior to FDG-PET for very early response prediction in NPM-ALK-positive lymphoma treated with targeted therapy. | Cancer research 20121001 |
| Hypoxia induces autophagy in primary human trophoblasts. | Endocrinology 20121001 |
| A single supratherapeutic dose of ridaforolimus does not prolong the QTc interval in patients with advanced cancer. | Cancer chemotherapy and pharmacology 20121001 |
| A phase I study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20121001 |
| Counteracting autophagy overcomes resistance to everolimus in mantle cell lymphoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20121001 |
| Everolimus in pediatric transplantation. | Current opinion in organ transplantation 20121001 |
| Antitumor activity of Triolimus: a novel multidrug-loaded micelle containing Paclitaxel, Rapamycin, and 17-AAG. | Molecular cancer therapeutics 20121001 |
| Analysis of cyclosporin A, tacrolimus, sirolimus, and everolimus in dried blood spot samples using liquid chromatography tandem mass spectrometry. | Analytical and bioanalytical chemistry 20121001 |
| Targeting androgen receptor leads to suppression of prostate cancer via induction of autophagy. | The Journal of urology 20121001 |
| Preventive and therapeutic effects of rapamycin, a mammalian target of rapamycin inhibitor, on food allergy in mice. | Allergy 20121001 |
| Arsenic trioxide synergizes with everolimus (Rad001) to induce cytotoxicity of ovarian cancer cells through increased autophagy and apoptosis. | Endocrine-related cancer 20121001 |
| An evaluation of sirolimus in renal transplantation. | Expert opinion on drug metabolism & toxicology 20121001 |
| Everolimus and erlotinib as second- or third-line therapy in patients with advanced non-small-cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20121001 |
| Target of rapamycin (TOR) controls vitellogenesis via activation of the S6 kinase in the fat body of the tick, Haemaphysalis longicornis. | International journal for parasitology 20121001 |
| Successful sirolimus graded dose challenge in an erythromycin-allergic patient. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20121001 |
| Sirolimus in renal transplantation: analysis of safety and efficacy in a nonprotocol conversion group. | Transplantation proceedings 20121001 |
| Sirolimus as rescue therapy after liver transplantation. | Transplantation proceedings 20121001 |
| Pain syndrome induced by calcineurin inhibitor and resolved by conversion to sirolimus in a child after kidney transplantation: a case report. | Transplantation proceedings 20121001 |
| Topical use of rapamycin in herpetic stromal keratitis. | Ocular immunology and inflammation 20121001 |
| Comparison of twelve-month outcomes after percutanous coronary intervention with everolimus-eluting versus zotarolimus-eluting or sirolimus-eluting stents from the PROENCY (PROmus ENdeavor CYpher) registry. | The Journal of invasive cardiology 20121001 |
| Late stent thrombosis of a second-generation drug- eluting stent. | The Journal of invasive cardiology 20121001 |
| Comparison of paclitaxal vs. sirolimus eluting stents with bio-degradable polymer for the treatment of coronary bifurcation lesions: subgroup analysis from DKCRUSH-I and DKCRUSH-II studies. | Chinese medical journal 20121001 |
| Vascular healing in drug-eluting stents: differential drug-associated response of limus-eluting stents in a preclinical model of stent implantation. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20121001 |
| Enhanced drug delivery capabilities from stents coated with absorbable polymer and crystalline drug. | Journal of controlled release : official journal of the Controlled Release Society 20120928 |
| Folate-conjugated rapamycin slows progression of polycystic kidney disease. | Journal of the American Society of Nephrology : JASN 20120928 |
| Tuberin inhibits production of the matrix protein fibronectin in diabetes. | Journal of the American Society of Nephrology : JASN 20120928 |
| Targeting of mTORC1/2 by the mTOR kinase inhibitor PP242 induces apoptosis in AML cells under conditions mimicking the bone marrow microenvironment. | Blood 20120927 |
| Wound healing complications and the use of mammalian target of rapamycin inhibitors in kidney transplantation: a critical review of the literature. | Transplantation 20120927 |
| An elaborate regulation of Mammalian target of rapamycin activity is required for somatic cell reprogramming induced by defined transcription factors. | Stem cells and development 20120920 |
| Serum lactate dehydrogenase predicts for overall survival benefit in patients with metastatic renal cell carcinoma treated with inhibition of mammalian target of rapamycin. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120920 |
| Rapamycin impairs UV induction of mutant-p53 overexpressing cell clusters without affecting tumor onset. | International journal of cancer 20120915 |
| Co-administration strategy to enhance brain accumulation of vandetanib by modulating P-glycoprotein (P-gp/Abcb1) and breast cancer resistance protein (Bcrp1/Abcg2) mediated efflux with m-TOR inhibitors. | International journal of pharmaceutics 20120915 |
| Cost-effectiveness of everolimus- versus paclitaxel-eluting stents for patients undergoing percutaneous coronary revascularization (from the SPIRIT-IV Trial). | The American journal of cardiology 20120915 |
| Immunomodulatory synergy by combining atorvastatin and rapamycin in the treatment of experimental autoimmune encephalomyelitis (EAE). | Journal of neuroimmunology 20120915 |
| Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress. | American journal of physiology. Renal physiology 20120915 |
| Leptin-induced mTOR activation defines a specific molecular and transcriptional signature controlling CD4+ effector T cell responses. | Journal of immunology (Baltimore, Md. : 1950) 20120915 |
| Heme oxygenase-1 promotes survival of renal cancer cells through modulation of apoptosis- and autophagy-regulating molecules. | The Journal of biological chemistry 20120914 |
| mTOR inhibition prevents epithelial stem cell senescence and protects from radiation-induced mucositis. | Cell stem cell 20120907 |
| Rapamycin down-regulates KCC2 expression and increases seizure susceptibility to convulsants in immature rats. | Neuroscience 20120906 |
| A neurotrophic hypothesis of depression: role of synaptogenesis in the actions of NMDA receptor antagonists. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20120905 |
| Rapamycin delays disease onset and prevents PrP plaque deposition in a mouse model of Gerstmann-Sträussler-Scheinker disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120905 |
| Antileukaemia effect of rapamycin alone or in combination with daunorubicin on Ph+ acute lymphoblastic leukaemia cell line. | Hematological oncology 20120901 |
| Central pontine myelinolysis: a case report and clinical-pathological review. | Pediatric transplantation 20120901 |
| Castleman disease in a pediatric liver transplant recipient: a case report and literature review. | Pediatric transplantation 20120901 |
| Successful sirolimus rescue in tacrolimus-induced thrombotic microangiopathy after living-related liver transplantation. | Pediatric transplantation 20120901 |
| In vivo comparison of a polymer-free Biolimus A9-eluting stent with a biodegradable polymer-based Biolimus A9 eluting stent and a bare metal stent in balloon denuded and radiated hypercholesterolemic rabbit iliac arteries. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120901 |
| Randomized comparison of cost-saving and effectiveness of oral rapamycin plus bare-metal stents with drug-eluting stents: three-year outcome from the randomized oral rapamycin in Argentina (ORAR) III trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120901 |
| Sirolimus - moving toward the mainstream in pediatric heart transplantation? | Pediatric transplantation 20120901 |
| K-Ras mutation-mediated IGF-1-induced feedback ERK activation contributes to the rapalog resistance in pancreatic ductal adenocarcinomas. | Cancer letters 20120901 |
| Enduring response to everolimus as third-line therapy in a patient with advanced renal cell carcinoma, including small-bowel metastases: loss of FHIT but normal VHL gene status. | Clinical genitourinary cancer 20120901 |
| Repetitive angioscopic observations of a sirolimus-eluting stent deployed in a patient with silent chronic thrombotic occlusion. | Cardiovascular intervention and therapeutics 20120901 |
| The development of novel biodegradable bifurcation stents for the sustainable release of anti-proliferative sirolimus. | Annals of biomedical engineering 20120901 |
| Indications for an alternative effective treatment of head and neck squamous cell carcinoma with temsirolimus plus bevacizumab: from bench to bedside? | Anti-cancer drugs 20120901 |
| Post-transplantation encapsulating peritoneal sclerosis in a pediatric patient. | Pediatric nephrology (Berlin, Germany) 20120901 |
| The novel combination of sirolimus and bortezomib prevents graft-versus-host disease but maintains the graft-versus-leukemia effect after allogeneic transplantation. | Haematologica 20120901 |
| Conversion to sirolimus in pediatric renal transplant patients: a single-center experience. | Pediatric transplantation 20120901 |
| Safety of posaconazole and sirolimus coadministration in allogeneic hematopoietic stem cell transplants. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120901 |
| Characterization of Foxp3 gene from grass carp (Ctenopharyngodon idellus): a rapamycin-inducible transcription factor in teleost immune system. | Developmental and comparative immunology 20120901 |
| Role of Toll-like receptor 2 in the immune response against hepadnaviral infection. | Journal of hepatology 20120901 |
| Case of complete response to everolimus for metastatic renal cell carcinoma. | International journal of urology : official journal of the Japanese Urological Association 20120901 |
| The long-term efficacy of cilostazol in addition to dual antiplatelet therapy after sirolimus-eluting stent implantation for Japanese patients: an analysis of the 3-year follow-up outcomes from the j-Cypher registry. | Cardiovascular intervention and therapeutics 20120901 |
| Sirolimus: more cause for alarm? | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120901 |
| Impact of sirolimus and tacrolimus on mortality and graft loss in liver transplant recipients with or without hepatitis C virus: an analysis of the Scientific Registry of Transplant Recipients Database. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120901 |
| Reduced intensity allogeneic hematopoietic stem cell transplantation for MDS using tacrolimus/sirolimus-based GVHD prophylaxis. | Leukemia research 20120901 |
| Sorafenib enhances the therapeutic efficacy of rapamycin in colorectal cancers harboring oncogenic KRAS and PIK3CA. | Carcinogenesis 20120901 |
| Contractile activity-induced mitochondrial biogenesis and mTORC1. | American journal of physiology. Cell physiology 20120901 |
| Efficacy of everolimus, a novel mTOR inhibitor, against basal-like triple-negative breast cancer cells. | Cancer science 20120901 |
| Rapamycin induces p53-independent apoptosis through the mitochondrial pathway in non-small cell lung cancer cells. | Oncology reports 20120901 |
| Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function. | Diabetes 20120901 |
| Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype. | Cancer gene therapy 20120901 |
| Development of a lymphangioleiomyomatosis model by endonasal administration of human TSC2-/- smooth muscle cells in mice. | The American journal of pathology 20120901 |
| Randomized controlled trial of sirolimus conversion in cardiac transplant recipients with renal insufficiency. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120901 |
| Rapamycin for treatment of type I autosomal dominant polycystic kidney disease (RAPYD-study): a randomized, controlled study. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120901 |
| PDGF receptor alpha is an alternative mediator of rapamycin-induced Akt activation: implications for combination targeted therapy of synovial sarcoma. | Cancer research 20120901 |
| Effect of immunosuppressive drugs on spontaneous DNA repair in human peripheral blood mononuclear cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120901 |
| Does everolimus increase donor-specific HLA antibodies in kidney transplant recipients? | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120901 |
| Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model. | Cancer research 20120901 |
| Dual targeting of mTOR and aurora-A kinase for the treatment of uterine Leiomyosarcoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120901 |
| Perifosine enhances mTORC1-targeted cancer therapy by activation of GSK3β in NSCLC cells. | Cancer biology & therapy 20120901 |
| Serum and glucocorticoid-regulated kinase 1 (SGK1) activation in breast cancer: requirement for mTORC1 activity associates with ER-alpha expression. | Breast cancer research and treatment 20120901 |
| Phase II study of the safety and efficacy of temsirolimus in East Asian patients with advanced renal cell carcinoma. | Japanese journal of clinical oncology 20120901 |
| Temsirolimus: a safety and efficacy review. | Expert opinion on drug safety 20120901 |
| Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120901 |
| ESX-1 dependent impairment of autophagic flux by Mycobacterium tuberculosis in human dendritic cells. | Autophagy 20120901 |
| Inhibition of mTOR in carcinoid tumors. | Targeted oncology 20120901 |
| A novel image-based cytometry method for autophagy detection in living cells. | Autophagy 20120901 |
| The role of mTOR signaling pathway in spinal cord injury. | Cell cycle (Georgetown, Tex.) 20120901 |
| Incidence and risk of pulmonary toxicity in patients treated with mTOR inhibitors for malignancy. A meta-analysis of published trials. | Acta oncologica (Stockholm, Sweden) 20120901 |
| Renal angiomyolipomatosis and Kaposi's sarcoma: a possible link disrupted by sirolimus. | Internal and emergency medicine 20120901 |
| Resistance to targeted therapies in pancreatic neuroendocrine tumors (PNETs): molecular basis, preclinical data, and counteracting strategies. | Targeted oncology 20120901 |
| Immunotherapy in type 1 diabetes: a shorter but more winding road? | Diabetes 20120901 |
| Topical rapamycin therapy to alleviate the cutaneous manifestations of tuberous sclerosis complex: a double-blind, randomized, controlled trial to evaluate the safety and efficacy of topically applied rapamycin. | Drugs in R&D 20120901 |
| Everolimus: a new treatment option for advanced pancreatic neuroendocrine tumors. | The Annals of pharmacotherapy 20120901 |
| Conversion from calcineurin inhibitors to everolimus with low-dose cyclosporine in renal transplant recipients with squamous cell carcinoma of the skin. | Transplantation proceedings 20120901 |
| Everolimus and enteric-coated mycophenolate sodium ab initio after liver transplantation: midterm results. | Transplantation proceedings 20120901 |
| Caffeine induces apoptosis of osteosarcoma cells by inhibiting AKT/mTOR/S6K, NF-κB and MAPK pathways. | Anticancer research 20120901 |
| Comparative evaluation of small-molecule chemosensitizers in reversal of cisplatin resistance in ovarian cancer cells. | Anticancer research 20120901 |
| Long-term vascular healing in response to sirolimus- and paclitaxel-eluting stents: an optical coherence tomography study. | JACC. Cardiovascular interventions 20120901 |
| [Treatment of pulmonary and retroperitoneal lymphangioleiomyomatosis with rapamycin: a case presentation and literature review]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20120901 |
| Drug choices in autoimmune hepatitis: part B--Nonsteroids. | Expert review of gastroenterology & hepatology 20120901 |
| Emerging agents for the treatment of mantle cell lymphoma. | Expert review of anticancer therapy 20120901 |
| Clinical trial end points for assessing efficacy of novel therapies for soft-tissue sarcomas. | Expert review of anticancer therapy 20120901 |
| Intranasal rapamycin rescues mice from staphylococcal enterotoxin B-induced shock. | Toxins 20120901 |
| Autistic-like behaviour and cerebellar dysfunction in Purkinje cell Tsc1 mutant mice. | Nature 20120830 |
| Effectiveness of a combination therapy using calcineurin inhibitor and mTOR inhibitor in preventing allograft rejection and post-transplantation renal cancer progression. | Cancer letters 20120828 |
| Constitutive activation of the mTOR signaling pathway within the normal glomerulus. | Biochemical and biophysical research communications 20120824 |
| Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial. | JAMA 20120822 |
| New-generation drug-eluting stents for patients with myocardial infarction. | JAMA 20120822 |
| Resistance to the mTOR-inhibitor RAD001 elevates integrin α2- and β1-triggered motility, migration and invasion of prostate cancer cells. | British journal of cancer 20120821 |
| Metabotropic actions of the volatile anaesthetic sevoflurane increase protein kinase M synthesis and induce immediate preconditioning protection of rat hippocampal slices. | The Journal of physiology 20120815 |
| Activation of genes involved in xenobiotic metabolism is a shared signature of mouse models with extended lifespan. | American journal of physiology. Endocrinology and metabolism 20120815 |
| The mTOR-inhibitor rapamycin mediates proteinuria in nephrotoxic serum nephritis by activating the innate immune response. | American journal of physiology. Renal physiology 20120815 |
| Multiple roles for mammalian target of rapamycin signaling in both glutamatergic and GABAergic synaptic transmission. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20120815 |
| Resolution of chylous pulmonary congestion and respiratory failure in lymphangioleiomyomatosis with sirolimus therapy. | American journal of respiratory and critical care medicine 20120815 |
| Sirolimus-eluting stents for treatment of infrapopliteal arteries reduce clinical event rate compared to bare-metal stents: long-term results from a randomized trial. | Journal of the American College of Cardiology 20120814 |
| Stent elution rate determines drug deposition and receptor-mediated effects. | Journal of controlled release : official journal of the Controlled Release Society 20120810 |
| Efficacy of rapamycin for refractory hemangioendotheliomas in Maffucci's syndrome. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120810 |
| Rapamycin ameliorates age-dependent obesity associated with increased mTOR signaling in hypothalamic POMC neurons. | Neuron 20120809 |
| The Cdc48 protein and its cofactor Vms1 are involved in Cdc13 protein degradation. | The Journal of biological chemistry 20120803 |
| Sirolimus and everolimus intestinal absorption and interaction with calcineurin inhibitors: a differential effect between cyclosporine and tacrolimus. | Fundamental & clinical pharmacology 20120801 |
| Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS. | Neurobiology of aging 20120801 |
| Unprotected left main coronary artery stenting with zotarolimus (Endeavor) drug-eluting stents: a single center retrospective experience. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120801 |
| Phase I and pharmacokinetic study of capecitabine and the oral mTOR inhibitor everolimus in patients with advanced solid malignancies. | Investigational new drugs 20120801 |
| A role for maintenance therapy in managing sarcoma. | Cancer treatment reviews 20120801 |
| Optical coherence tomographic comparison of neointimal coverage between sirolimus- and resolute zotarolimus-eluting stents at 9 months after stent implantation. | The international journal of cardiovascular imaging 20120801 |
| Analysis of 1 year virtual histology changes in coronary plaque located behind the struts of the everolimus eluting bioresorbable vascular scaffold. | The international journal of cardiovascular imaging 20120801 |
| Frequency and impact of bleeding in elective coronary stent clinical trials--utility of three commonly used definitions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120801 |
| Rapamycin inhibits transforming growth factor β-induced peritoneal angiogenesis by blocking the secondary hypoxic response. | Journal of cellular and molecular medicine 20120801 |
| PKI-587 and sorafenib targeting PI3K/AKT/mTOR and Ras/Raf/MAPK pathways synergistically inhibit HCC cell proliferation. | The Journal of surgical research 20120801 |
| Rapamycin induced ultrastructural and molecular alterations in glomerular podocytes in healthy mice. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120801 |
| Rapamycin induces heme oxygenase-1 in liver but inhibits bile flow recovery after ischemia. | The Journal of surgical research 20120801 |
| Mao-B elevation decreases parkin's ability to efficiently clear damaged mitochondria: protective effects of rapamycin. | Free radical research 20120801 |
| Treatment of coronary bifurcation lesions with drug-eluting stents: insights from the first phase of the prospective multicenter german drug-eluting stent registry. | Journal of interventional cardiology 20120801 |
| Rapamycin inhibits the invasive ability of thyroid cancer cells by down-regulating the expression of VEGF-C in vitro. | Cell biochemistry and function 20120801 |
| Low-dose rapamycin treatment increases the ability of human regulatory T cells to inhibit transplant arteriosclerosis in vivo. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120801 |
| Connective tissue growth factor (CTGF/CCN2): a protagonist in cardiac allograft vasculopathy development? | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120801 |
| The inhibitory effect of rapamycin on the oval cell response and development of preneoplastic foci in the rat. | Experimental and molecular pathology 20120801 |
| Combined use of rapamycin and leflunomide in prevention of acute cardiac allografts rejection in rats. | Transplant immunology 20120801 |
| Comparative assessment of transient exposure of paclitaxel or zotarolimus on in vitro vascular cell death, proliferation, migration, and proinflammatory biomarker expression. | Journal of cardiovascular pharmacology 20120801 |
| Autophagy sustains the replication of porcine reproductive and respiratory virus in host cells. | Virology 20120801 |
| Randomized phase II trial of everolimus in combination with tamoxifen in patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative metastatic breast cancer with prior exposure to aromatase inhibitors: a GINECO study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120801 |
| Sirolimus modulates HIVAN phenotype through inhibition of epithelial mesenchymal transition. | Experimental and molecular pathology 20120801 |
| Rapamycin slows aging in mice. | Aging cell 20120801 |
| Immunosuppressive drugs on inducing Ag-specific CD4(+)CD25(+)Foxp3(+) Treg cells during immune response in vivo. | Transplant immunology 20120801 |
| Stability of GABAB receptor oligomers revealed by dual TR-FRET and drug-induced cell surface targeting. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120801 |
| Inhibition of the mTOR/S6K signal is necessary to enhance fluorouracil-induced apoptosis in gastric cancer cells with HER2 amplification. | International journal of oncology 20120801 |
| Synergistic activity of the mTOR inhibitor ridaforolimus and the antiandrogen bicalutamide in prostate cancer models. | International journal of oncology 20120801 |
| Sulforaphane, a cruciferous vegetable-derived isothiocyanate, inhibits protein synthesis in human prostate cancer cells. | Biochimica et biophysica acta 20120801 |
| Monitoring autophagic flux by an improved tandem fluorescent-tagged LC3 (mTagRFP-mWasabi-LC3) reveals that high-dose rapamycin impairs autophagic flux in cancer cells. | Autophagy 20120801 |
| Impact of oncogenic driver mutations on feedback between the PI3K and MEK pathways in cancer cells. | Bioscience reports 20120801 |
| Combination of sorafenib and everolimus impacts therapeutically on adrenocortical tumor models. | Endocrine-related cancer 20120801 |
| Prevention of age-related macular degeneration-like retinopathy by rapamycin in rats. | The American journal of pathology 20120801 |
| Xience side branch access stent for treatment of bifurcation coronary disease: a review of preclinical data. | Journal of interventional cardiology 20120801 |
| Phase I study of bevacizumab, everolimus, and panobinostat (LBH-589) in advanced solid tumors. | Cancer chemotherapy and pharmacology 20120801 |
| TORC1 of fission yeast is rapamycin-sensitive. | Genes to cells : devoted to molecular & cellular mechanisms 20120801 |
| Flow patterns at stented coronary bifurcations: computational fluid dynamics analysis. | Circulation. Cardiovascular interventions 20120801 |
| Pregnancy in a kidney transplant patient treated with everolimus. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20120801 |
| Non-clear cell renal cell carcinoma: does the mammalian target of rapamycin represent a rational therapeutic target? | The oncologist 20120801 |
| Targeting angiogenesis in metastatic breast cancer. | The oncologist 20120801 |
| The mTOR inhibitor everolimus in combination with carboplatin in metastatic breast cancer--a phase I trial. | Anticancer research 20120801 |
| Brain metastasis in a patient with a sarcomatoid variant RCC with well-controlled extracerebral metastases by temsirolimus. | Anticancer research 20120801 |
| [Soft-tissue sarcoma: recent developments]. | Deutsche medizinische Wochenschrift (1946) 20120801 |
| How to save Medicare: the anti-aging remedy. | Aging 20120801 |
| Stromal liver kinase B1 [STK11] signaling loss induces oviductal adenomas and endometrial cancer by activating mammalian Target of Rapamycin Complex 1. | PLoS genetics 20120801 |
| Paclitaxcel-coated balloon plus bare metal stent vs. sirolimus-eluting stent in de novo lesions: an IVUS study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120801 |
| In silico prediction for the investigation of comedication interferences in quantitative LC-MS detection in the SRM mode. | Bioanalysis 20120801 |
| Stromal cell-derived factor 1α mediates resistance to mTOR-directed therapy in pancreatic cancer. | Neoplasia (New York, N.Y.) 20120801 |
| Second-generation everolimus-eluting stents versus first-generation sirolimus-eluting stents in acute myocardial infarction. 1-year results of the randomized XAMI (XienceV Stent vs. Cypher Stent in Primary PCI for Acute Myocardial Infarction) trial. | Journal of the American College of Cardiology 20120731 |
| Transient sequestration of TORC1 into stress granules during heat stress. | Molecular cell 20120727 |
| Rapamycin attenuates aggressive behavior in a rat model of pilocarpine-induced epilepsy. | Neuroscience 20120726 |
| Sirolimus and secondary skin-cancer prevention in kidney transplantation. | The New England journal of medicine 20120726 |
| Temsirolimus activates autophagy and ameliorates cardiomyopathy caused by lamin A/C gene mutation. | Science translational medicine 20120725 |
| Rapamycin reverses elevated mTORC1 signaling in lamin A/C-deficient mice, rescues cardiac and skeletal muscle function, and extends survival. | Science translational medicine 20120725 |
| Multistage pH-responsive liposomes for mitochondrial-targeted anticancer drug delivery. | Advanced materials (Deerfield Beach, Fla.) 20120717 |
| Protein translocation as a tool: The current rapamycin story. | FEBS letters 20120716 |
| Preliminary experience with personalized and targeted therapy for pediatric brain tumors. | Pediatric blood & cancer 20120715 |
| Mammalian target of rapamycin and the kidney. II. Pathophysiology and therapeutic implications. | American journal of physiology. Renal physiology 20120715 |
| The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex. | Human molecular genetics 20120715 |
| Calcium/calmodulin-dependent protein kinase IV limits organ damage in hepatic ischemia-reperfusion injury through induction of autophagy. | American journal of physiology. Gastrointestinal and liver physiology 20120715 |
| Novel agents and new combination treatments on phase I studies on solid tumors and pancreatic cancer. | JOP : Journal of the pancreas 20120710 |
| Insulin stimulates IGFBP-2 expression in 3T3-L1 adipocytes through the PI3K/mTOR pathway. | Molecular and cellular endocrinology 20120706 |
| Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1. | The Journal of biological chemistry 20120706 |
| Pharmacological rescue of mitochondrial deficits in iPSC-derived neural cells from patients with familial Parkinson's disease. | Science translational medicine 20120704 |
| TNFα-mediated apoptosis in human osteoarthritic chondrocytes sensitized by PI3K-NF-κB inhibitor, not mTOR inhibitor. | Rheumatology international 20120701 |
| Impact of renal insufficiency on safety and efficacy of drug-eluting stents compared to bare-metal stents at 6 years. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120701 |
| Everolimus is an active agent in medullary thyroid cancer: a clinical and in vitro study. | Journal of cellular and molecular medicine 20120701 |
| Rapamycin affects tissue plasminogen activator and plasminogen activator inhibitor I expression: a potential prothrombotic mechanism of drug-eluting stents. | Angiology 20120701 |
| Preliminary report of the use of everolimus in a patient with progressive medullary thyroid carcinoma. | Clinical endocrinology 20120701 |
| Everolimus in combination with cyclosporin a as pre- and posttransplantation immunosuppressive therapy in nonmyeloablative allogeneic hematopoietic stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20120701 |
| Dasatinib synergizes with both cytotoxic and signal transduction inhibitors in heterogeneous breast cancer cell lines--lessons for design of combination targeted therapy. | Cancer letters 20120701 |
| A multicenter phase II trial (SAKK 36/06) of single-agent everolimus (RAD001) in patients with relapsed or refractory mantle cell lymphoma. | Haematologica 20120701 |
| Optimisation of the tumour response threshold in patients treated with everolimus for metastatic renal cell carcinoma: analysis of response and progression-free survival in the RECORD-1 study. | European journal of cancer (Oxford, England : 1990) 20120701 |
| Different involvement of autophagy in human malignant glioma cell lines undergoing irradiation and temozolomide combined treatments. | Journal of cellular biochemistry 20120701 |
| Low-dose sirolimus-eluting hydroxyapatite coating on stents does not increase platelet activation and adhesion ex vivo. | Journal of thrombosis and thrombolysis 20120701 |
| Effects of the combination of RAD001 and docetaxel on breast cancer stem cells. | European journal of cancer (Oxford, England : 1990) 20120701 |
| What do you do with the antiplatelet agents in patients with drug eluting stents who then receive a mechanical valve? | Interactive cardiovascular and thoracic surgery 20120701 |
| Phase II study of sirolimus in treatment-naive patients with advanced hepatocellular carcinoma. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120701 |
| Impact of routine angiographic follow-up after percutaneous coronary intervention with drug-eluting stents in the SPIRIT III randomized trial at three years. | The American journal of cardiology 20120701 |
| Pneumonitis associated with mTOR inhibitors therapy in patients with metastatic renal cell carcinoma: incidence, radiographic findings and correlation with clinical outcome. | European journal of cancer (Oxford, England : 1990) 20120701 |
| Five-year results of a randomized trial comparing de novo sirolimus and cyclosporine in renal transplantation: the SPIESSER study. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120701 |
| Re: Camillo Porta, Emiliano Calvo, Miguel A. Climent, et al. Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: an exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial. Eur Urol 2012;61:826-33. | European urology 20120701 |
| A randomized, controlled study to assess the conversion from calcineurin-inhibitors to everolimus after liver transplantation--PROTECT. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120701 |
| Functional analysis of the single Est1/Ebs1 homologue in Kluyveromyces lactis reveals roles in both telomere maintenance and rapamycin resistance. | Eukaryotic cell 20120701 |
| Combination of an allosteric Akt Inhibitor MK-2206 with etoposide or rapamycin enhances the antitumor growth effect in neuroblastoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120701 |
| Simultaneous targeting of EGFR and mTOR inhibits the growth of colorectal carcinoma cells. | Oncology reports 20120701 |
| Everolimus quantification in peripheral blood mononuclear cells using ultra high performance liquid chromatography tandem mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20120701 |
| Rapamycin and thrombosis. | Angiology 20120701 |
| Inhibition of mammalian target of rapamycin reduces epileptogenesis and blood-brain barrier leakage but not microglia activation. | Epilepsia 20120701 |
| Population pharmacokinetics and pharmacogenetics of everolimus in renal transplant patients. | Clinical pharmacokinetics 20120701 |
| A phase I study of bevacizumab, everolimus and panitumumab in advanced solid tumors. | Cancer chemotherapy and pharmacology 20120701 |
| A phase I study of temsirolimus plus carboplatin plus paclitaxel for patients with recurrent or metastatic (R/M) head and neck squamous cell cancer (HNSCC). | Cancer chemotherapy and pharmacology 20120701 |
| The minimal impact of food on the pharmacokinetics of ridaforolimus. | Cancer chemotherapy and pharmacology 20120701 |
| A study about drug combination therapy of Schisandra sphenanthera extract and Rapamycin in healthy subjects. | Canadian journal of physiology and pharmacology 20120701 |
| Caveolin-1 and accelerated host aging in the breast tumor microenvironment: chemoprevention with rapamycin, an mTOR inhibitor and anti-aging drug. | The American journal of pathology 20120701 |
| Everolimus: a challenging drug in the treatment of multifocal inoperable cardiac rhabdomyoma. | Pediatrics 20120701 |
| Primary care management of tuberous sclerosis complex in children. | Journal of the American Academy of Nurse Practitioners 20120701 |
| [Remission of an iatrogenic Kaposi sarcoma in a patient with myasthenia gravis after switching immunosuppressive therapy to the mTOR inhibitor everolimus]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20120701 |
| Implications of the new histological classification (WHO 2010) for pancreatic neuroendocrine neoplasms. | Annals of oncology : official journal of the European Society for Medical Oncology 20120701 |
| Dimerizer-mediated regulation of gene expression. | Cold Spring Harbor protocols 20120701 |
| Dimerizer-mediated regulation of gene expression in vitro. | Cold Spring Harbor protocols 20120701 |
| Dimerizer-mediated regulation of gene expression in vivo. | Cold Spring Harbor protocols 20120701 |
| Activation of the mTOR pathway in primary medullary thyroid carcinoma and lymph node metastases. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120701 |
| Efficacy of sequential treatment with sunitinib-everolimus in an orthotopic mouse model of renal cell carcinoma. | Anticancer research 20120701 |
| 14-3-3 protects against stress-induced apoptosis. | Cell death & disease 20120701 |
| Sirolimus versus calcineurin inhibitor-based immunosuppressive therapy in kidney transplantation: a 4-year follow-up. | Iranian journal of kidney diseases 20120701 |
| Symptomatic osteonecrosis of the femoral head after adult orthotopic liver transplantation. | Chinese medical journal 20120701 |
| In vivo evaluation of the delivery and efficacy of a sirolimus-laden polymer gel for inhibition of hyperplasia in a porcine model of arteriovenous hemodialysis graft stenosis. | Journal of controlled release : official journal of the Controlled Release Society 20120628 |
| Autophagy activation is associated with neuroprotection against apoptosis via a mitochondrial pathway in a rat model of subarachnoid hemorrhage. | Neuroscience 20120628 |
| mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake. | Nature 20120628 |
| The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and activation is a mechanism of resistance. | The Journal of biological chemistry 20120622 |
| Inhibition of the mTORC2 and chaperone pathways to treat leukemia. | Blood 20120621 |
| mTOR inhibitors synergize on regression, reversal of gene expression, and autophagy in hepatocellular carcinoma. | Science translational medicine 20120620 |
| The FKBP-rapamycin binding domain of human TOR undergoes strong conformational changes in the presence of membrane mimetics with and without the regulator phosphatidic acid. | Biochemistry 20120619 |
| Selective ATP-competitive inhibitors of TOR suppress rapamycin-insensitive function of TORC2 in Saccharomyces cerevisiae. | ACS chemical biology 20120615 |
| Attenuation of TORC1 signaling delays replicative and oncogenic RAS-induced senescence. | Cell cycle (Georgetown, Tex.) 20120615 |
| Suppression of replicative senescence by rapamycin in rodent embryonic cells. | Cell cycle (Georgetown, Tex.) 20120615 |
| Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients. | Transplantation 20120615 |
| Identification and expansion of highly suppressive CD8(+)FoxP3(+) regulatory T cells after experimental allogeneic bone marrow transplantation. | Blood 20120614 |
| Long-term clinical and angiographic outcome after treatment of chronic total occlusion with everolimus or sirolimus eluting stents. | International journal of cardiology 20120614 |
| Short- and long-term outcomes with drug-eluting and bare-metal coronary stents: a mixed-treatment comparison analysis of 117 762 patient-years of follow-up from randomized trials. | Circulation 20120612 |
| Lipopolysaccharide induction of autophagy is associated with enhanced bactericidal activity in Dictyostelium discoideum. | Biochemical and biophysical research communications 20120608 |
| Further developments for improving response and tolerance to irradiation for advanced renal cancer: concurrent (mTOR) inhibitor RAD001 and helical tomotherapy. | Investigational new drugs 20120601 |
| Everolimus-related organizing pneumonia: a report establishing causality. | Investigational new drugs 20120601 |
| Temsirolimus in renal cell carcinoma with sarcomatoid differentiation: a report of three cases. | Medical oncology (Northwood, London, England) 20120601 |
| p70 S6K1 nuclear localization depends on its mTOR-mediated phosphorylation at T389, but not on its kinase activity towards S6. | Amino acids 20120601 |
| Combination or sequencing strategies to improve the outcome of metastatic renal cell carcinoma patients: a critical review. | Critical reviews in oncology/hematology 20120601 |
| 40-O -[2-Hydroxyethyl]rapamycin modulates human dendritic cell function during exposure to Aspergillus fumigatus. | Journal of basic microbiology 20120601 |
| Alpha-ketoglutarate inhibits glutamine degradation and enhances protein synthesis in intestinal porcine epithelial cells. | Amino acids 20120601 |
| Early treatment with everolimus exerts nephroprotective effect in rats with adriamycin-induced nephrotic syndrome. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601 |
| Primary anti-vascular endothelial growth factor (VEGF)-refractory metastatic renal cell carcinoma: clinical characteristics, risk factors, and subsequent therapy. | Annals of oncology : official journal of the European Society for Medical Oncology 20120601 |
| Autophagy modulates osteoarthritis-related gene expression in human chondrocytes. | Arthritis and rheumatism 20120601 |
| Rapamycin and a hyaluronic acid-carboxymethylcellulose membrane did not lead to reduced adhesion formations in a rat abdominal adhesion model. | Archives of gynecology and obstetrics 20120601 |
| Interstitial pneumonitis is a frequent complication in liver transplant recipients treated with sirolimus. | Irish journal of medical science 20120601 |
| Is there a role for targeted therapies in the collecting ducts of Bellini carcinoma? Efficacy data from a retrospective analysis of 7 cases. | Clinical and experimental nephrology 20120601 |
| Impact of incomplete stent apposition on long-term clinical outcome after drug-eluting stent implantation. | European heart journal 20120601 |
| Inhibition of neointimal hyperplasia with a novel zotarolimus coated balloon catheter. | Clinical research in cardiology : official journal of the German Cardiac Society 20120601 |
| Hypothalamic mTOR pathway mediates thyroid hormone-induced hyperphagia in hyperthyroidism. | The Journal of pathology 20120601 |
| Regulatory T cells exhibit decreased proliferation but enhanced suppression after pulsing with sirolimus. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120601 |
| Inhibition of mammalian target of rapamycin signaling by CCI-779 (temsirolimus) induces growth inhibition and cell cycle arrest in Cashmere goat fetal fibroblasts (Capra hircus). | DNA and cell biology 20120601 |
| Combination of Temsirolimus and tyrosine kinase inhibitors in renal carcinoma and endothelial cell lines. | Journal of cancer research and clinical oncology 20120601 |
| Sirolimus protective effects on bone: the need to be demonstrated. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120601 |
| Cyclosporine lowering with everolimus versus mycophenolate mofetil in heart transplant recipients: long-term follow-up of the SHIRAKISS randomized, prospective study. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120601 |
| Mammalian target of rapamycin: a valid therapeutic target through the autophagy pathway for Alzheimer's disease? | Journal of neuroscience research 20120601 |
| Post-transcriptional modulation of C/EBPα prompts monocytic differentiation and apoptosis in acute myelomonocytic leukaemia cells. | Leukemia research 20120601 |
| Modulation of mTOR effector phosphoproteins in blood basophils from allergic patients. | Journal of clinical immunology 20120601 |
| System for integrated adherence monitoring: real-time non-adherence risk assessment in pediatric kidney transplantation. | Pediatric transplantation 20120601 |
| Modulation of sodium iodide symporter expression and function by LY294002, Akti-1/2 and Rapamycin in thyroid cells. | Endocrine-related cancer 20120601 |
| A single-dose placebo- and moxifloxacin-controlled study of the effects of temsirolimus on cardiac repolarization in healthy adults. | Cancer chemotherapy and pharmacology 20120601 |
| Immunophyllin ligands show differential effects on alcohol self-administration in C57BL mice. | The Journal of pharmacology and experimental therapeutics 20120601 |
| Ghrelin contributes to derangements of glucose metabolism induced by rapamycin in mice. | Diabetologia 20120601 |
| Gli inhibitor GANT61 causes apoptosis in myeloid leukemia cells and acts in synergy with rapamycin. | Leukemia research 20120601 |
| The role of mTOR inhibitors in the inhibition of growth and cortisol secretion in human adrenocortical carcinoma cells. | Endocrine-related cancer 20120601 |
| A novel library screen identifies immunosuppressors that promote osteoblast differentiation. | Bone 20120601 |
| Everolimus-eluting versus sirolimus-eluting stents: an updated meta-analysis of randomized trials. | Clinical research in cardiology : official journal of the German Cardiac Society 20120601 |
| Influence of diabetes mellitus on long-term (five-year) outcomes of drug-eluting stents and coronary artery bypass grafting for multivessel coronary revascularization. | The American journal of cardiology 20120601 |
| Pancreatic neuroendocrine and carcinoid tumors: what's new, what's old, and what's different? | Current oncology reports 20120601 |
| Effect of everolimus on pre-existing atherosclerosis in LDL-receptor deficient mice. | Atherosclerosis 20120601 |
| Measuring adherence to medications: are complex methods superior to simple ones? | Pediatric transplantation 20120601 |
| Inhibition of mTORC1 kinase activates Smads 1 and 5 but not Smad8 in human prostate cancer cells, mediating cytostatic response to rapamycin. | Molecular cancer research : MCR 20120601 |
| Subconjunctival sirolimus for the treatment of chronic active anterior uveitis: results of a pilot trial. | American journal of ophthalmology 20120601 |
| Major involvement of mTOR in the PPARγ-induced stimulation of adipose tissue lipid uptake and fat accretion. | Journal of lipid research 20120601 |
| Luteinizing hormone facilitates angiogenesis in ovarian epithelial tumor cells and metformin inhibits the effect through the mTOR signaling pathway. | Oncology reports 20120601 |
| The impact of sirolimus on sex hormones in male adolescent kidney recipients. | Pediatric transplantation 20120601 |
| Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120601 |
| Immunosuppressive regimen and interstitial fibrosis and tubules atrophy at 12 months postrenal transplant. | Clinical journal of the American Society of Nephrology : CJASN 20120601 |
| Combination of Rad001 (everolimus) and propachlor synergistically induces apoptosis through enhanced autophagy in prostate cancer cells. | Molecular cancer therapeutics 20120601 |
| A role of the mammalian target of rapamycin (mTOR) in glutamate-induced down-regulation of tuberous sclerosis complex proteins 2 (TSC2). | Journal of molecular neuroscience : MN 20120601 |
| Endothelial-dependent vasomotion in a coronary segment treated by ABSORB everolimus-eluting bioresorbable vascular scaffold system is related to plaque composition at the time of bioresorption of the polymer: indirect finding of vascular reparative therapy? | European heart journal 20120601 |
| Serum cholesterol and mTOR inhibitors: surrogate biomarker or epiphenomenon? | Clinical cancer research : an official journal of the American Association for Cancer Research 20120601 |
| Circulating biomarkers of response to sunitinib in gastroenteropancreatic neuroendocrine tumors: current data and clinical outlook. | Molecular diagnosis & therapy 20120601 |
| Cordycepin as a sensitizer to tumour necrosis factor (TNF)-α-induced apoptosis through eukaryotic translation initiation factor 2α (eIF2α)- and mammalian target of rapamycin complex 1 (mTORC1)-mediated inhibition of nuclear factor (NF)-κB. | Clinical and experimental immunology 20120601 |
| Cap-independent Nrf2 translation is part of a lipoic acid-stimulated detoxification stress response. | Biochimica et biophysica acta 20120601 |
| Results of a phase II study of sirolimus and cyclophosphamide in patients with advanced sarcoma. | European journal of cancer (Oxford, England : 1990) 20120601 |
| Effect of sirolimus on the regression of peritoneal sclerosis in an experimental rat model. | International urology and nephrology 20120601 |
| Histopathological comparison of biodegradable polymer and permanent polymer based sirolimus eluting stents in a porcine model of coronary stent implantation. | Thrombosis and haemostasis 20120601 |
| Radiosensitization of renal cell carcinoma in vitro through the induction of autophagy. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20120601 |
| A further step towards vascular reparative therapy. | European heart journal 20120601 |
| SIRT1 is required for the effects of rapamycin on high glucose-inducing mesangial cells senescence. | Mechanisms of ageing and development 20120601 |
| Autophagy and cardiovascular aging: lesson learned from rapamycin. | Cell cycle (Georgetown, Tex.) 20120601 |
| New targeted agents in gastroenteropancreatic neuroendocrine tumors. | Targeted oncology 20120601 |
| Everolimus in different combinations as maintenance immunosuppressive therapy in heart transplant recipients. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120601 |
| Everolimus-induced lymphedema in a renal transplant recipient: a case report. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120601 |
| Conversion from cyclosporine to everolimus at 4.5 months posttransplant: 3-year results from the randomized ZEUS study. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120601 |
| [Renal carcinoma: point on treatment of brain metastasis]. | Bulletin du cancer 20120601 |
| Peritoneovenous shunt for chylous ascites after lung transplantation for lymphangioleiomyomatosis. | Transplantation proceedings 20120601 |
| Gender differences in patients treated with the zotarolimus-eluting stent at a tertiary medical center. | The Journal of invasive cardiology 20120601 |
| Targeting mTOR in mantle cell lymphoma: current and future directions. | Best practice & research. Clinical haematology 20120601 |
| Malignant perivascular epithelioid cell tumor in children: description of a case and review of the literature. | Journal of pediatric surgery 20120601 |
| Lymphedema of the breast as a symptom of internal diseases or side effect of mTor inhibitors. | Lymphatic research and biology 20120601 |
| Contemporary incidence and predictors of stent thrombosis and other major adverse cardiac events in the year after XIENCE V implantation: results from the 8,061-patient XIENCE V United States study. | JACC. Cardiovascular interventions 20120601 |
| The role of autophagy during coxsackievirus infection of neural progenitor and stem cells. | Autophagy 20120601 |
| Dissecting mammalian target of rapamycin to promote longevity. | Rejuvenation research 20120601 |
| The BOLERO-2 trial: the addition of everolimus to exemestane in the treatment of postmenopausal hormone receptor-positive advanced breast cancer. | Future oncology (London, England) 20120601 |
| Medium to long-term clinical outcomes with everolimus-eluting stents in real-life percutaneous coronary intervention. | Annals of the Academy of Medicine, Singapore 20120601 |
| Proteinuria following sirolimus conversion is associated with deterioration of kidney function in liver transplant recipients. | Transplantation 20120527 |
| Evaluation of the peri-strut low intensity area following sirolimus- and paclitaxel-eluting stents implantation: insights from an optical coherence tomography study in humans. | International journal of cardiology 20120517 |
| Clinical performance of a drug-eluting stent with a biodegradable polymer in an unselected patient population: the NOBORI 2 study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515 |
| mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes. | Molecular and cellular endocrinology 20120515 |
| Sirolimus-associated testicular toxicity: detrimental but reversible. | Transplantation 20120515 |
| Impact of statin therapy on late target lesion revascularization after sirolimus-eluting stent implantation (from the CREDO-Kyoto Registry Cohort-2). | The American journal of cardiology 20120515 |
| Radiochemical high-performance liquid chromatography detection of arginine metabolism in human endothelial cells. | Analytical biochemistry 20120515 |
| Stable isotope-labelling analysis of the impact of inhibition of the mammalian target of rapamycin on protein synthesis. | The Biochemical journal 20120515 |
| Impact of age on clinical outcomes after everolimus-eluting and paclitaxel-eluting stent implantation: pooled analysis from the SPIRIT III and SPIRIT IV clinical trials. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515 |
| Late clinical outcomes after implantation of drug-eluting stents coated with biodegradable polymers: 3-year follow-up of the PAINT randomised trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120515 |
| Inhibition of influenza A virus replication by antagonism of a PI3K-AKT-mTOR pathway member identified by gene-trap insertional mutagenesis. | Antiviral chemistry & chemotherapy 20120514 |
| Use of sirolimus in patients with primary steroid-resistant nephrotic syndrome. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20120514 |
| Reduction of Na/K-ATPase potentiates marinobufagenin-induced cardiac dysfunction and myocyte apoptosis. | The Journal of biological chemistry 20120511 |
| A perivascular system releasing sirolimus prevented intimal hyperplasia in a rabbit model in a medium-term study. | International journal of pharmaceutics 20120510 |
| Regulation of the glutamate transporter EAAT3 by mammalian target of rapamycin mTOR. | Biochemical and biophysical research communications 20120504 |
| Flat panel digital detector cinefluoroscopy late following SES or BMS implantation for detection of coronary stent fracture in asymptomatic patients. | International journal of cardiology 20120503 |
| Everolimus in HR-positive advanced breast cancer. | The New England journal of medicine 20120503 |
| Everolimus in HR-positive advanced breast cancer. | The New England journal of medicine 20120503 |
| TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO. | Cell metabolism 20120502 |
| Agreement and reproducibility of gray-scale intravascular ultrasound and optical coherence tomography for the analysis of the bioresorbable vascular scaffold. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501 |
| Seven-year safety and efficacy of the unrestricted use of drug-eluting stents in saphenous vein bypass grafts. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501 |
| Combination testing (Stage 2) of the Anti-IGF-1 receptor antibody IMC-A12 with rapamycin by the pediatric preclinical testing program. | Pediatric blood & cancer 20120501 |
| Successful coronary intervention of chronic total occlusion of the right coronary artery by ipsilateral injection via an isolated conus artery. | Heart and vessels 20120501 |
| A phase 1 study of weekly everolimus (RAD001) in combination with docetaxel in patients with metastatic breast cancer. | Cancer 20120501 |
| Suppression of neointimal hyperplasia by sirolimus-eluting expanded polytetrafluoroethylene (ePTFE) haemodialysis grafts in comparison with paclitaxel-coated grafts. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120501 |
| Rapamycin induces glucose intolerance in mice by reducing islet mass, insulin content, and insulin sensitivity. | Journal of molecular medicine (Berlin, Germany) 20120501 |
| Repeat-dose sirolimus pharmacokinetics and pharmacodynamics in patients with hepatic allografts. | European journal of clinical pharmacology 20120501 |
| The union of anti-CD34 antibody can improve the performance of drug-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501 |
| Upregulation of mTORC2 activation by the selective agonist of EPAC, 8-CPT-2Me-cAMP, in prostate cancer cells: assembly of a multiprotein signaling complex. | Journal of cellular biochemistry 20120501 |
| Molecular characterization and functional analysis of Cashmere goat mammalian target of rapamycin. | DNA and cell biology 20120501 |
| Magnetic stents retain nanoparticle-bound antirestenotic drugs transported by lipid microbubbles. | Pharmaceutical research 20120501 |
| Assay validation of phosphorylated S6 ribosomal protein for a pharmacodynamic monitoring of mTOR-inhibitors in peripheral human blood. | Cytometry. Part B, Clinical cytometry 20120501 |
| Analysis of the pharmacodynamic activity of the mTOR inhibitor ridaforolimus (AP23573, MK-8669) in a phase 1 clinical trial. | Cancer chemotherapy and pharmacology 20120501 |
| Sorafenib for recurrence of hepatocellular carcinoma after liver transplantation. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120501 |
| Preparation and optimization of media using Pluronic® micelles for solubilization of sirolimus and release from the drug eluting stents. | Colloids and surfaces. B, Biointerfaces 20120501 |
| V-AKT murine thymoma viral oncogene homolog/mammalian target of rapamycin activation induces a module of metabolic changes contributing to growth in insulin-induced hepatocarcinogenesis. | Hepatology (Baltimore, Md.) 20120501 |
| Sustained antitumor activity by co-targeting mTOR and the microtubule with temsirolimus/vinblastine combination in hepatocellular carcinoma. | Biochemical pharmacology 20120501 |
| The effect of multiple doses of rifampin and ketoconazole on the single-dose pharmacokinetics of ridaforolimus. | Cancer chemotherapy and pharmacology 20120501 |
| Everolimus exhibits efficacy as a radiosensitizer in a model of non-small cell lung cancer. | Oncology reports 20120501 |
| Impact of sirolimus duration on hepatitis C related fibrosis progression in liver transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501 |
| An indirect comparison of everolimus versus sorafenib in metastatic renal cell carcinoma - a flawed analysis? | Expert opinion on pharmacotherapy 20120501 |
| Donor-specific HLA antibodies in a cohort comparing everolimus with cyclosporine after kidney transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501 |
| Rapamycin toxicity in MIN6 cells and rat and human islets is mediated by the inhibition of mTOR complex 2 (mTORC2). | Diabetologia 20120501 |
| Akt inhibitors MK-2206 and nelfinavir overcome mTOR inhibitor resistance in diffuse large B-cell lymphoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120501 |
| Safety and efficacy of the XIENCE V everolimus-eluting stent compared to first-generation drug-eluting stents in contemporary clinical practice. | The American journal of cardiology 20120501 |
| Dose-dependent effects of sirolimus on mTOR signaling and polycystic kidney disease. | Journal of the American Society of Nephrology : JASN 20120501 |
| Everolimus triggers cytokine release by macrophages: rationale for stents eluting everolimus and a glucocorticoid. | Arteriosclerosis, thrombosis, and vascular biology 20120501 |
| Systemic rapamycin alone may not be a treatment option for malignant glioma: evidence from an in vivo study. | Journal of neuro-oncology 20120501 |
| Acute depletion of plasma membrane phosphatidylinositol 4,5-bisphosphate impairs specific steps in endocytosis of the G-protein-coupled receptor. | Journal of cell science 20120501 |
| Treatment of congenital tracheal stenosis by balloon-expandable metallic stents in paediatric intensive care unit. | Interactive cardiovascular and thoracic surgery 20120501 |
| Autophagy proteins play cytoprotective and cytocidal roles in leucine starvation-induced cell death in Saccharomyces cerevisiae. | Autophagy 20120501 |
| Effects of rapamycin-induced oligomerization of parvalbumin, Stim1 and Orai1 in puncta formation. | Cell calcium 20120501 |
| The impact of sirolimus on sex hormones in male adolescent kidney recipients. | Pediatric transplantation 20120501 |
| Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term triple therapy. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501 |
| Cavitatory lung disease in thoracic transplant recipients receiving sirolimus. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120501 |
| mTOR is required for asymmetric division through small GTPases in mouse oocytes. | Molecular reproduction and development 20120501 |
| mTOR as a molecular target in HPV-associated oral and cervical squamous carcinomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120501 |
| Randomized controlled trial of sirolimus for renal transplant recipients at high risk for nonmelanoma skin cancer. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501 |
| Regulation of mTOR complex 2 signaling in neurofibromatosis 2-deficient target cell types. | Molecular cancer research : MCR 20120501 |
| Patterns of interstitial lung disease during everolimus treatment in patients with metastatic renal cell carcinoma. | Japanese journal of clinical oncology 20120501 |
| Limus is not limus--a proposal to adjust terminology in the context of drug-eluting stents. | Journal of cardiovascular pharmacology 20120501 |
| Biodegradable polymer drug-eluting stents reduce the risk of stent thrombosis at 4 years in patients undergoing percutaneous coronary intervention: a pooled analysis of individual patient data from the ISAR-TEST 3, ISAR-TEST 4, and LEADERS randomized trials. | European heart journal 20120501 |
| Inhibition of mammalian target of rapamycin augments lipopolysaccharide-induced lung injury and apoptosis. | Journal of immunology (Baltimore, Md. : 1950) 20120501 |
| Insulin growth factor-receptor (IGF-1R) antibody cixutumumab combined with the mTOR inhibitor temsirolimus in patients with refractory Ewing's sarcoma family tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120501 |
| Activation of ER stress and mTORC1 suppresses hepatic sortilin-1 levels in obese mice. | The Journal of clinical investigation 20120501 |
| Cyclosporin but not everolimus inhibits chemokine receptor expression on CD4+ T cell subsets circulating in the peripheral blood of renal transplant recipients. | Clinical and experimental immunology 20120501 |
| Everolimus plus early tacrolimus minimization: a phase III, randomized, open-label, multicentre trial in renal transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20120501 |
| Possible correlation of sirolimus plasma concentration with sinusoidal obstructive syndrome of the liver in patients undergoing myeloablative allogeneic hematopoietic cell transplantation. | Pharmacotherapy 20120501 |
| A brain aggregate model gives new insights into the pathobiology and treatment of prion diseases. | Journal of neuropathology and experimental neurology 20120501 |
| Objective versus subjective guidance of (bioabsorbable) stent implantation: the saga continues. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501 |
| Proximal and distal maximal luminal diameters as a guide to appropriate deployment of the ABSORB everolimus-eluting bioresorbable vascular scaffold: a sub-study of the ABSORB Cohort B and the on-going ABSORB EXTEND Single Arm Study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120501 |
| Emerging treatments in the management of tuberous sclerosis complex. | Pediatric neurology 20120501 |
| mTOR inhibitors: a myth, a cure for cancer or something in between? | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120501 |
| Comment on 'Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells' Haematologica 2011;96(9):1357-65. | Haematologica 20120501 |
| Cardiac allograft vasculopathy compared by intravascular ultrasound sonography: everolimus to mycophenolate mofetil--one single-center experience. | Transplantation proceedings 20120501 |
| Clinical experience of tacrolimus with everolimus in heart transplantation. | Transplantation proceedings 20120501 |
| Metformin and the mTOR inhibitor everolimus (RAD001) sensitize breast cancer cells to the cytotoxic effect of chemotherapeutic drugs in vitro. | Anticancer research 20120501 |
| The SPIRIT V diabetic study: a randomized clinical evaluation of the XIENCE V everolimus-eluting stent vs the TAXUS Liberté paclitaxel-eluting stent in diabetic patients with de novo coronary artery lesions. | American heart journal 20120501 |
| Long-term clinical and angiographic outcomes of diabetic patients after revascularization with early generation drug-eluting stents. | American heart journal 20120501 |
| The impact of preprocedural hemoglobin A1c on the efficacy of sirolimus-eluting and paclitaxel-eluting stents. | Cardiovascular intervention and therapeutics 20120501 |
| Stability of ready-to-use temsirolimus infusion solution (100mg/L) in polypropylene containers under different storage conditions. | Annales pharmaceutiques francaises 20120501 |
| Systemic exposure of sirolimus after coronary stent implantation in patients with de novo coronary lesions: Supralimus-Core® pharmacokinetic study. | Indian heart journal 20120501 |
| Once again on rapamycin-induced insulin resistance and longevity: despite of or owing to. | Aging 20120501 |
| [Progress and extensive meaning of mammalian target of rapamycin involved in restoration of nervous system injury]. | Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery 20120501 |
| Brief report: a phase II 'window-of-opportunity' frontline study of the MTOR inhibitor, temsirolimus given as a single agent in patients with advanced NSCLC, an NCCTG study. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120501 |
| Late subcapsular lymphocele in a kidney graft. | Transplantation 20120427 |
| The pan-deacetylase inhibitor panobinostat induces cell death and synergizes with everolimus in Hodgkin lymphoma cell lines. | Blood 20120426 |
| Regulation of presynaptic neurotransmission by macroautophagy. | Neuron 20120426 |
| Short- versus long-term duration of dual-antiplatelet therapy after coronary stenting: a randomized multicenter trial. | Circulation 20120424 |
| Everolimus in metastatic renal cell carcinoma patients intolerant to previous VEGFr-TKI therapy: a RECORD-1 subgroup analysis. | British journal of cancer 20120424 |
| Drug-eluting vs bare-metal stents in primary angioplasty: a pooled patient-level meta-analysis of randomized trials. | Archives of internal medicine 20120423 |
| Effect of persistent activation of phosphoinositide 3-kinase on heart. | Life sciences 20120420 |
| PI3-kinase and mTOR inhibitors differently modulate the function of the ABCG2 multidrug transporter. | Biochemical and biophysical research communications 20120420 |
| Surface crystallization of rapamycin on stents using a temperature induced process. | Langmuir : the ACS journal of surfaces and colloids 20120417 |
| Rapamycin with antiretroviral therapy in AIDS-associated Kaposi sarcoma: an AIDS Malignancy Consortium study. | Journal of acquired immune deficiency syndromes (1999) 20120415 |
| Murine islet allograft tolerance upon blockade of the B-lymphocyte stimulator, BLyS/BAFF. | Transplantation 20120415 |
| Blocking mTORC1 activity by rapamycin leads to impairment of spatial memory retrieval but not acquisition in C57BL/6J mice. | Behavioural brain research 20120415 |
| Production of interferon α by human immunodeficiency virus type 1 in human plasmacytoid dendritic cells is dependent on induction of autophagy. | The Journal of infectious diseases 20120415 |
| The struggle for energy in podocytes leads to nephrotic syndrome. | Cell cycle (Georgetown, Tex.) 20120415 |
| Stent thrombosis with drug-eluting and bare-metal stents: evidence from a comprehensive network meta-analysis. | Lancet (London, England) 20120414 |
| Controlled release formulations of IL-2, TGF-β1 and rapamycin for the induction of regulatory T cells. | Journal of controlled release : official journal of the Controlled Release Society 20120410 |
| Primary endpoint results of the EVOLVE trial: a randomized evaluation of a novel bioabsorbable polymer-coated, everolimus-eluting coronary stent. | Journal of the American College of Cardiology 20120410 |
| A randomized controlled trial in second-generation zotarolimus-eluting Resolute stents versus everolimus-eluting Xience V stents in real-world patients: the TWENTE trial. | Journal of the American College of Cardiology 20120410 |
| Inhibition of chemokine (CXC motif) ligand 12/chemokine (CXC motif) receptor 4 axis (CXCL12/CXCR4)-mediated cell migration by targeting mammalian target of rapamycin (mTOR) pathway in human gastric carcinoma cells. | The Journal of biological chemistry 20120406 |
| Des-acyl ghrelin exhibits pro-anabolic and anti-catabolic effects on C2C12 myotubes exposed to cytokines and reduces burn-induced muscle proteolysis in rats. | Molecular and cellular endocrinology 20120404 |
| Yin Yang 1 deficiency in skeletal muscle protects against rapamycin-induced diabetic-like symptoms through activation of insulin/IGF signaling. | Cell metabolism 20120404 |
| Regulation of hepatic LDL receptors by mTORC1 and PCSK9 in mice. | The Journal of clinical investigation 20120402 |
| A phase I study of temsirolimus and metformin in advanced solid tumours. | Investigational new drugs 20120401 |
| Combination testing of cediranib (AZD2171) against childhood cancer models by the pediatric preclinical testing program. | Pediatric blood & cancer 20120401 |
| Sirolimus and mycophenolate mofetil as GVHD prophylaxis in myeloablative, matched-related donor hematopoietic cell transplantation. | Bone marrow transplantation 20120401 |
| Major determinants for the uncovered stent struts on optical coherence tomography after drug-eluting stent implantation. | The international journal of cardiovascular imaging 20120401 |
| Optical coherence tomography findings of very late stent thrombosis after drug-eluting stent implantation. | The international journal of cardiovascular imaging 20120401 |
| Combination of targeted agents in metastatic renal cell carcinoma: a path forward or a dead-end street? | Cancer 20120401 |
| Phase 1 trial of everolimus plus sunitinib in patients with metastatic renal cell carcinoma. | Cancer 20120401 |
| Chronic mTOR inhibition by rapamycin induces muscle insulin resistance despite weight loss in rats. | British journal of pharmacology 20120401 |
| Krüppel-like factor 4 is induced by rapamycin and mediates the anti-proliferative effect of rapamycin in rat carotid arteries after balloon injury. | British journal of pharmacology 20120401 |
| Mechanical injury suppresses autophagy regulators and pharmacologic activation of autophagy results in chondroprotection. | Arthritis and rheumatism 20120401 |
| Ridaforolimus for patients with progressive or recurrent malignant glioma: a perisurgical, sequential, ascending-dose trial. | Cancer chemotherapy and pharmacology 20120401 |
| Dynamic contrast-enhanced micro-CT on mice with mammary carcinoma for the assessment of antiangiogenic therapy response. | European radiology 20120401 |
| Autophagy activation by rapamycin reduces severity of experimental osteoarthritis. | Annals of the rheumatic diseases 20120401 |
| Morphological and degradation studies of sirolimus-containing poly(lactide-co-glycolide) discs. | Journal of biomedical materials research. Part B, Applied biomaterials 20120401 |
| Molecular targeted agents for gastric and gastroesophageal junction cancer. | Surgery today 20120401 |
| Phase I study for ridaforolimus, an oral mTOR inhibitor, in Japanese patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20120401 |
| Identification of a novel biomarker gene set with sensitivity and specificity for distinguishing between allograft rejection and tolerance. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120401 |
| Combined mTOR inhibition and OX40 agonism enhances CD8(+) T cell memory and protective immunity produced by recombinant adenovirus vaccines. | Molecular therapy : the journal of the American Society of Gene Therapy 20120401 |
| Regulatory T cells expanded by rapamycin in vitro suppress colitis in an experimental mouse model. | Journal of gastroenterology 20120401 |
| Immunosuppressive drug rapamycin restores sporulation competence in industrial yeasts. | Journal of bioscience and bioengineering 20120401 |
| Pharmacologic inhibition of mTOR antagonizes the cytotoxic activity of pemetrexed in non-small cell lung cancer. | Journal of cancer research and clinical oncology 20120401 |
| Regulation of physiologic actions of LRRK2: focus on autophagy. | Neuro-degenerative diseases 20120401 |
| Autophagy is a cell death mechanism in Toxoplasma gondii. | Cellular microbiology 20120401 |
| Lifelong rapamycin administration ameliorates age-dependent cognitive deficits by reducing IL-1β and enhancing NMDA signaling. | Aging cell 20120401 |
| Meta-analysis of long-term outcomes for drug-eluting stents versus bare-metal stents in primary percutaneous coronary interventions for ST-segment elevation myocardial infarction. | The American journal of cardiology 20120401 |
| TOR signaling is involved in PTTH-stimulated ecdysteroidogenesis by prothoracic glands in the silkworm, Bombyx mori. | Insect biochemistry and molecular biology 20120401 |
| Development of a combination drug-eluting bead: towards enhanced efficacy for locoregional tumour therapies. | Anti-cancer drugs 20120401 |
| Determination of everolimus in blood samples from kidney and liver transplant recipients using the sirolimus chemiluminescence magnetic microparticle immunoassay (CMIA) on the Architect-i1000® system. | Scandinavian journal of clinical and laboratory investigation 20120401 |
| Adhesion and cohesion in structures containing suspended microscopic polymeric films. | Acta biomaterialia 20120401 |
| Radical reduction of smooth muscle cells in explanted lung of a LAM patient treated with sirolimus: first case report. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120401 |
| Everolimus-eluting stents and paclitaxel-eluting stents in patients presenting with myocardial infarction: insights from the two-year results of the COMPARE prospective randomised controlled trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401 |
| Potential of T-regulatory cells to protect xenografts. | Current opinion in organ transplantation 20120401 |
| Induced regulatory T cells: mechanisms of conversion and suppressive potential. | Human immunology 20120401 |
| Efficacy and safety of everolimus in elderly patients with metastatic renal cell carcinoma: an exploratory analysis of the outcomes of elderly patients in the RECORD-1 Trial. | European urology 20120401 |
| TORC2 signaling is antagonized by protein phosphatase 2A and the Far complex in Saccharomyces cerevisiae. | Genetics 20120401 |
| Role of rapamycin-induced autophagy in pancreatic islets. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120401 |
| Comparison of biolimus eluted from an erodible stent coating with bare metal stents in acute ST-elevation myocardial infarction (COMFORTABLE AMI trial): rationale and design. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401 |
| Rapamycin resistance is linked to defective regulation of Skp2. | Cancer research 20120401 |
| Immunological advantages of everolimus versus cyclosporin A in liver-transplanted recipients, as revealed by polychromatic flow cytometry. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20120401 |
| Early conversion to a sirolimus-based, calcineurin-inhibitor-free immunosuppression in the SMART trial: observational results at 24 and 36months after transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20120401 |
| Analytical performance of a new liquid chromatography/tandem mass spectrometric method for determination of everolimus concentrations in whole blood. | Therapeutic drug monitoring 20120401 |
| New strategies for advanced neuroendocrine tumors in the era of targeted therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120401 |
| Effects of an agonist interleukin-2/Fc fusion protein, a mutant antagonist interleukin-15/Fc fusion protein, and sirolimus on cardiac allograft survival in non-human primates. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120401 |
| Regulating mammalian target of rapamycin to tune vaccination-induced CD8(+) T cell responses for tumor immunity. | Journal of immunology (Baltimore, Md. : 1950) 20120401 |
| Blue rubber bleb nevus syndrome: successful treatment with sirolimus. | Pediatrics 20120401 |
| Comparison of 5-year clinical outcomes between sirolimus-versus paclitaxel-eluting stent: Korean multicenter network analysis of 9000-patient cohort. | Circulation. Cardiovascular interventions 20120401 |
| Everolimus: preventing organ rejection in adult kidney transplant recipients. | Expert opinion on pharmacotherapy 20120401 |
| Impact of stenting and oral sirolimus on endothelium-dependent and independent coronary vasomotion. | Arquivos brasileiros de cardiologia 20120401 |
| Long-term results of conversion from calcineurin inhibitors to sirolimus in 150 maintenance kidney transplant patients. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120401 |
| Sirolimus conversion in liver transplant recipients with calcineurin inhibitor-induced complications: efficacy and safety. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120401 |
| Periprocedural myocardial infarction in a randomized trial of everolimus-eluting and Paclitaxel-eluting coronary stents: frequency and impact on mortality according to historic versus universal definitions. | Circulation. Cardiovascular interventions 20120401 |
| Targeting autophagy for drug-induced hepatotoxicity. | Autophagy 20120401 |
| Everolimus: targeted therapy on the horizon for the treatment of breast cancer. | Pharmacotherapy 20120401 |
| Autophagy: a new therapeutic target in cartilage injury and osteoarthritis. | The Journal of the American Academy of Orthopaedic Surgeons 20120401 |
| Acute ST-elevation myocardial infarction 6 years following a sirolimus-eluting stent secondary to complete stent fracture. | The Journal of invasive cardiology 20120401 |
| Successful sealing of a coronary artery perforation with a mesh-covered stent. | The Journal of invasive cardiology 20120401 |
| The 4-week serum creatinine level predicts long-term renal dysfunction after adult living donor liver transplantation. | Transplantation proceedings 20120401 |
| Rapamycin combined with allogenic immature dendritic cells selectively expands CD4+CD25+Foxp3+ regulatory T cells in rats. | Hepatobiliary & pancreatic diseases international : HBPD INT 20120401 |
| Suppression of autophagy is protective in high glucose-induced cardiomyocyte injury. | Autophagy 20120401 |
| Breakthroughs in myeloproliferative neoplasms. | Hematology (Amsterdam, Netherlands) 20120401 |
| mTOR-dependent modulation of gastric nesfatin-1/NUCB2. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120401 |
| The prequel: defining prognostically important criteria in the periprocedural PCI troponin saga. | Circulation. Cardiovascular interventions 20120401 |
| Magnetic nanoparticles and rapamycin encapsulated into polymeric nanocarriers. | Journal of biomedical nanotechnology 20120401 |
| Differences in neointimal thickness between the adluminal and the abluminal sides of malapposed and side-branch struts in a polylactide bioresorbable scaffold: evidence in vivo about the abluminal healing process. | JACC. Cardiovascular interventions 20120401 |
| Nobori stent shows less vascular inflammation and early recovery of endothelial function compared with Cypher stent. | JACC. Cardiovascular interventions 20120401 |
| DUrable polymer-based sTent CHallenge of Promus ElemEnt versus ReSolute integrity (DUTCH PEERS): rationale and study design of a randomized multicenter trial in a Dutch all-comers population. | American heart journal 20120401 |
| ComparisOn of neointimal coVerage betwEen zotaRolimus-eluting stent and everolimus-eluting stent using Optical Coherence Tomography (COVER OCT). | American heart journal 20120401 |
| Optical coherence tomography (OCT) evaluation after coronary stenting: the 'black hole' and other low OCT signal-intensity areas. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401 |
| Atypical 'black hole' phenomenon after treatment of sirolimus stent restenosis with a paclitaxel-coated balloon. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401 |
| Serial optical coherence tomography imaging of the 'black-hole' phenomenon by intravascular ultrasound following sirolimus-eluting stent implantation. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120401 |
| Targeted therapeutics in treatment of children and young adults with solid tumors: an expert survey and review of the literature. | Klinische Padiatrie 20120401 |
| Rapamycin increases oxidative stress response gene expression in adult stem cells. | Aging 20120401 |
| Plasmonic photothermic and stem cell therapy of atherosclerotic plaque as a novel nanotool for angioplasty and artery remodeling. | Rejuvenation research 20120401 |
| [Effect of rapamycin on high glucose-induced autophagy impairment, oxidative stress and premature senescence in rat mesangial cells in vitro]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20120401 |
| Drug-eluting vs. bare metal stents for symptomatic vertebral artery stenosis. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20120401 |
| [Rapamycin inhibits the proliferation of prostate cancer cell line 22RV1 and activity of S6K1]. | Zhonghua nan ke xue = National journal of andrology 20120401 |
| Phase II study of concurrent radiation therapy, temozolomide, and bevacizumab followed by bevacizumab/everolimus as first-line treatment for patients with glioblastoma. | Clinical advances in hematology & oncology : H&O 20120401 |
| TOR signaling regulates ribosome and tRNA synthesis via LAMMER/Clk and GSK-3 family kinases. | Molecular cell 20120330 |
| Rapamycin suppresses the recurrent excitatory circuits of dentate gyrus in a mouse model of temporal lobe epilepsy. | Biochemical and biophysical research communications 20120330 |
| The TOR complex 1 is a direct target of Rho1 GTPase. | Molecular cell 20120330 |
| Cell biology. Rapamycin paradox resolved. | Science (New York, N.Y.) 20120330 |
| Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity. | Science (New York, N.Y.) 20120330 |
| Chronic activation of mTOR complex 1 is sufficient to cause hepatocellular carcinoma in mice. | Science signaling 20120327 |
| Hyperplexing: a method for higher-order multiplexed quantitative proteomics provides a map of the dynamic response to rapamycin in yeast. | Science signaling 20120327 |
| Rapid and orthogonal logic gating with a gibberellin-induced dimerization system. | Nature chemical biology 20120325 |
| Transcription factor Foxo1 represses T-bet-mediated effector functions and promotes memory CD8(+) T cell differentiation. | Immunity 20120323 |
| Rapamycin promotes autophagy and reduces neural tissue damage and locomotor impairment after spinal cord injury in mice. | Journal of neurotrauma 20120320 |
| Randomized trial of optimal treatment strategies for in-stent restenosis after drug-eluting stent implantation. | Journal of the American College of Cardiology 20120320 |
| Rapamycin enhances docetaxel-induced cytotoxicity in a androgen-independent prostate cancer xenograft model by survivin downregulation. | Biochemical and biophysical research communications 20120316 |
| Single-cell pharmacodynamic monitoring of S6 ribosomal protein phosphorylation in AML blasts during a clinical trial combining the mTOR inhibitor sirolimus and intensive chemotherapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120315 |
| Innate and adaptive immune responses are tolerized in chimeras prepared with nonmyeloablative conditioning. | Transplantation 20120315 |
| Macrophage-induced tumor angiogenesis is regulated by the TSC2-mTOR pathway. | Cancer research 20120315 |
| Phospho-specific flow: fixating on the target. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120315 |
| Effect of everolimus on left ventricular hypertrophy of de novo kidney transplant recipients: a 1 year, randomized, controlled trial. | Transplantation 20120315 |
| Ovarian toxicity from sirolimus. | The New England journal of medicine 20120315 |
| PIK3CA/PTEN mutations and Akt activation as markers of sensitivity to allosteric mTOR inhibitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120315 |
| Randomized comparison of everolimus-eluting and sirolimus-eluting stents in patients treated with percutaneous coronary intervention: the Scandinavian Organization for Randomized Trials with Clinical Outcome IV (SORT OUT IV). | Circulation 20120313 |
| Phase II study of everolimus with biomarker exploration in patients with advanced gastric cancer refractory to chemotherapy including fluoropyrimidine and platinum. | British journal of cancer 20120313 |
| Ridaforolimus in advanced sarcomas: a leap forward or missed opportunity? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120310 |
| Spatio-temporal manipulation of small GTPase activity at subcellular level and on timescale of seconds in living cells. | Journal of visualized experiments : JoVE 20120309 |
| Intratumor heterogeneity and branched evolution revealed by multiregion sequencing. | The New England journal of medicine 20120308 |
| Very late coronary stent thrombosis of a newer-generation everolimus-eluting stent compared with early-generation drug-eluting stents: a prospective cohort study. | Circulation 20120306 |
| Synergistic anti-tumor effects of RAD001 with MEK inhibitors in neuroendocrine tumors: a potential mechanism of therapeutic limitation of mTOR inhibitor. | Molecular and cellular endocrinology 20120305 |
| Quantitative multi-modality imaging analysis of a fully bioresorbable stent: a head-to-head comparison between QCA, IVUS and OCT. | The international journal of cardiovascular imaging 20120301 |
| Rapamycin attenuates the expression of cocaine-induced place preference and behavioral sensitization. | Addiction biology 20120301 |
| Favorable neointimal coverage in everolimus-eluting stent at 9 months after stent implantation: comparison with sirolimus-eluting stent using optical coherence tomography. | The international journal of cardiovascular imaging 20120301 |
| Evaluation with in vivo optical coherence tomography and histology of the vascular effects of the everolimus-eluting bioresorbable vascular scaffold at two years following implantation in a healthy porcine coronary artery model: implications of pilot results for future pre-clinical studies. | The international journal of cardiovascular imaging 20120301 |
| Perioperative rupture of the LIMA graft leading to cardiogenic shock, emergency angiography, and stenting with a polytetrafluoroethylene-covered stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301 |
| Decreased risk of stent fracture-related restenosis between paclitaxel-eluting stents and sirolimus eluting stents: results of long-term follow-up. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301 |
| Incomplete arterial healing 8 years after the implantation of sirolimus-eluting stent. In vivo visualization by optical coherence tomography. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301 |
| Resolute Italian study in all comers: immediate and one-year outcomes. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301 |
| Sirolimus-eluting stent fracture detection by three-dimensional optical coherence tomography. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301 |
| Effects of everolimus in combination with sildenafil in monocrotaline-induced pulmonary hypertension in rats. | Cardiovascular toxicology 20120301 |
| New targeted therapies in pituitary carcinoma resistant to temozolomide. | Pituitary 20120301 |
| [Topical rapamycin solution to treat multiple facial angiofibromas in a patient with tuberous sclerosis]. | Actas dermo-sifiliograficas 20120301 |
| A phase I study of daily everolimus plus low-dose weekly cisplatin for patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20120301 |
| Mitochondrial autophagy in cells with mtDNA mutations results from synergistic loss of transmembrane potential and mTORC1 inhibition. | Human molecular genetics 20120301 |
| Withdrawal of proliferation signal inhibitors due to adverse events in the maintenance phase of heart transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120301 |
| Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis. | Leukemia research 20120301 |
| Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation. | Glia 20120301 |
| [Renal tolerance of targeted therapies]. | Bulletin du cancer 20120301 |
| Reduced phosphocholine and hyperpolarized lactate provide magnetic resonance biomarkers of PI3K/Akt/mTOR inhibition in glioblastoma. | Neuro-oncology 20120301 |
| Nutritional and hormonal regulation of the TOR effector 4E-binding protein (4E-BP) in the mosquito Aedes aegypti. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120301 |
| Phase I trial of everolimus plus sorafenib for patients with advanced renal cell cancer. | Clinical genitourinary cancer 20120301 |
| Clinical review: Current scientific rationale for the use of somatostatin analogs and mTOR inhibitors in neuroendocrine tumor therapy. | The Journal of clinical endocrinology and metabolism 20120301 |
| Role and therapeutic potential of PI3K-mTOR signaling in de novo resistance to BRAF inhibition. | Pigment cell & melanoma research 20120301 |
| Impairment of object recognition memory by rapamycin inhibition of mTOR in the amygdala or hippocampus around the time of learning or reactivation. | Behavioural brain research 20120301 |
| Sorafenib, a multikinase inhibitor, is effective in vitro against non-Hodgkin lymphoma and synergizes with the mTOR inhibitor rapamycin. | American journal of hematology 20120301 |
| Inhibition of MTOR disrupts autophagic flux in podocytes. | Journal of the American Society of Nephrology : JASN 20120301 |
| Circumferential evaluation of the neointima by optical coherence tomography after ABSORB bioresorbable vascular scaffold implantation: can the scaffold cap the plaque? | Atherosclerosis 20120301 |
| Rapamycin exerts antifungal activity in vitro and in vivo against Mucor circinelloides via FKBP12-dependent inhibition of Tor. | Eukaryotic cell 20120301 |
| Sirolimus conversion regimen versus continued calcineurin inhibitors in liver allograft recipients: a randomized trial. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120301 |
| The effects of immunosuppressants on vascular function, systemic oxidative stress and inflammation in rats. | Transplant international : official journal of the European Society for Organ Transplantation 20120301 |
| Safety and efficacy of local periadventitial delivery of sirolimus for improving hemodialysis graft patency: first human experience with a sirolimus-eluting collagen membrane (Coll-R). | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301 |
| Better stent expansion by two-time inflation of stent balloon and its responsible mechanism. | Journal of cardiology 20120301 |
| Rapamycin prevents the mutant huntingtin-suppressed GLT-1 expression in cultured astrocytes. | Acta pharmacologica Sinica 20120301 |
| Polycystic kidney disease: a 2011 update. | Current opinion in nephrology and hypertension 20120301 |
| mTOR inhibitors and its role in the treatment of head and neck squamous cell carcinoma. | Current treatment options in oncology 20120301 |
| Long-term kidney allograft function and survival in prednisone-free regimens: tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus. | Clinical journal of the American Society of Nephrology : CJASN 20120301 |
| Sirolimus conversion for renal dysfunction in liver transplant recipients: the devil really is in the details…. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120301 |
| Enhancing lysosome biogenesis attenuates BNIP3-induced cardiomyocyte death. | Autophagy 20120301 |
| Identification of autophagosome-associated proteins and regulators by quantitative proteomic analysis and genetic screens. | Molecular & cellular proteomics : MCP 20120301 |
| Comparing outcomes after off-pump coronary artery bypass versus drug-eluting stent in diabetic patients. | Journal of cardiology 20120301 |
| The haemodialysis arteriovenous graft: is a new era coming? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120301 |
| Fatal acute pulmonary injury associated with everolimus. | The Annals of pharmacotherapy 20120301 |
| Improvement in renal function after everolimus introduction and calcineurin inhibitor reduction in maintenance thoracic transplant recipients: the significance of baseline glomerular filtration rate. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20120301 |
| Molecular/genetic therapies in ovarian cancer: future opportunities and challenges. | Clinical obstetrics and gynecology 20120301 |
| Fixing a broken stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120301 |
| Rapamycin slows aging in mice. | Cell cycle (Georgetown, Tex.) 20120301 |
| Leptin regulates proliferation and apoptosis of colorectal carcinoma through PI3K/Akt/mTOR signalling pathway. | Journal of biosciences 20120301 |
| Current status of immunosuppressive agents for solid organ transplantation in children. | Pediatric transplantation 20120301 |
| Successful resolution of inflammation and increased regulatory T cells in sirolimus-treated post-transplant allograft hepatitis. | Pediatric transplantation 20120301 |
| Autophagy regulates endoplasmic reticulum stress in ischemic preconditioning. | Autophagy 20120301 |
| Therapeutic metformin/AMPK activation blocked lymphoma cell growth via inhibition of mTOR pathway and induction of autophagy. | Cell death & disease 20120301 |
| Advances in the treatment of relapsed or refractory Hodgkin's lymphoma. | The oncologist 20120301 |
| Cell cycle arrest is not yet senescence, which is not just cell cycle arrest: terminology for TOR-driven aging. | Aging 20120301 |
| mTOR kinase inhibitors as a treatment strategy in hematological malignancies. | Future medicinal chemistry 20120301 |
| Five-year follow-up of the Sirolimus-Eluting Stents vs Vascular Brachytherapy for Bare Metal In-Stent Restenosis (SISR) trial. | American heart journal 20120301 |
| Five-year results of the Multicenter Randomized Controlled Open-Label Study of the CYPHER Sirolimus-Eluting Stent in the Treatment of Diabetic Patients with De Novo Native Coronary Artery Lesions (SCORPIUS) study: a German multicenter investigation on the effectiveness of sirolimus-eluting stents in diabetic patients. | American heart journal 20120301 |
| Comparison of drug-eluting and bare-metal stents for primary percutaneous coronary intervention with or without abciximab in ST-segment elevation myocardial infarction: DEBATER: the Eindhoven reperfusion study. | JACC. Cardiovascular interventions 20120301 |
| Delamination of abluminal polymer of biolimus-eluting stent. | JACC. Cardiovascular interventions 20120301 |
| LMW-E/CDK2 deregulates acinar morphogenesis, induces tumorigenesis, and associates with the activated b-Raf-ERK1/2-mTOR pathway in breast cancer patients. | PLoS genetics 20120301 |
| SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians. | PLoS genetics 20120301 |
| Rapamycin inhibits lymphatic endothelial cell tube formation by downregulating vascular endothelial growth factor receptor 3 protein expression. | Neoplasia (New York, N.Y.) 20120301 |
| First report of a novel abluminal groove filled biodegradable polymer rapamycin-eluting stent in de novo coronary artery disease: results of the first in man FIREHAWK trial. | Chinese medical journal 20120301 |
| Safety and efficacy of cobalt chromium alloy based sirolimus-eluting stent with bioabsorbable polymer in porcine model. | Chinese medical journal 20120301 |
| [Rapamycin treatment of recurrent autoimmune hemolytic anemia in 28 cases]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20120301 |
| Everolimus as primary immunosuppression in kidney transplantation: experience in conversion from calcineurin inhibitors. | Transplantation 20120227 |
| Rapamycin reduces clinical signs and neuropathic pain in a chronic model of experimental autoimmune encephalomyelitis. | Journal of neuroimmunology 20120227 |
| Drug interaction between cyclosporine and mTOR inhibitors in experimental model of chronic cyclosporine nephrotoxicity and pancreatic islet dysfunction. | Transplantation 20120227 |
| Aberrant activation of the mTOR pathway and anti-tumour effect of everolimus on oesophageal squamous cell carcinoma. | British journal of cancer 20120227 |
| Amplification and demultiplexing in insulin-regulated Akt protein kinase pathway in adipocytes. | The Journal of biological chemistry 20120224 |
| Everolimus alters white matter diffusion in tuberous sclerosis complex. | Neurology 20120221 |
| New therapies for tuber-less sclerosis: white matter matters? | Neurology 20120221 |
| How many therapeutic options are there for recurrent or metastatic salivary duct carcinoma? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120220 |
| Inhibition of rapamycin-induced autophagy causes necrotic cell death associated with Bax/Bad mitochondrial translocation. | Neuroscience 20120217 |
| Post-treatment with rapamycin does not prevent epileptogenesis in the amygdala stimulation model of temporal lobe epilepsy. | Neuroscience letters 20120216 |
| Akt and p53 are potential mediators of reduced mammary tumor growth by cloroquine and the mTOR inhibitor RAD001. | Biochemical pharmacology 20120215 |
| Phase I study of the combination of sorafenib and temsirolimus in patients with metastatic melanoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120215 |
| Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438). | Clinical cancer research : an official journal of the American Association for Cancer Research 20120215 |
| Breast Cancer: Blocking both driver and escape pathways improves outcomes. | Nature reviews. Clinical oncology 20120214 |
| MNK2 inhibits eIF4G activation through a pathway involving serine-arginine-rich protein kinase in skeletal muscle. | Science signaling 20120214 |
| [Proliferation effects of sirolimus, cyclosporine A and mycophenolate mofetil on human transitional cell carcinoma cells]. | Zhonghua yi xue za zhi 20120214 |
| Hepatitis C virus NS5A binds to the mRNA cap-binding eukaryotic translation initiation 4F (eIF4F) complex and up-regulates host translation initiation machinery through eIF4E-binding protein 1 inactivation. | The Journal of biological chemistry 20120210 |
| Treatment of patients with advanced neurofibromatosis type 2 with novel molecularly targeted therapies: from bench to bedside. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120210 |
| Improved insulin sensitivity by rapamycin is associated with reduction of mTOR and S6K1 activities in L6 myotubes. | Biochemical and biophysical research communications 20120210 |
| Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer. | The New England journal of medicine 20120209 |
| Sirolimus as primary immunosuppression attenuates allograft vasculopathy with improved late survival and decreased cardiac events after cardiac transplantation. | Circulation 20120207 |
| Forced degradation studies of rapamycin: identification of autoxidation products. | Journal of pharmaceutical and biomedical analysis 20120205 |
| [Effect of casamino acid on intergeneric conjugation in rapamycin-producing Streptomyces hygroscopicus ATCC29253]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20120204 |
| Formation of tRNA granules in the nucleus of heat-induced human cells. | Biochemical and biophysical research communications 20120203 |
| Successful treatment of angiofibromata of tuberous sclerosis complex with rapamycin. | The Journal of dermatological treatment 20120201 |
| The combination of the novel glycolysis inhibitor 3-BrOP and rapamycin is effective against neuroblastoma. | Investigational new drugs 20120201 |
| Schedule-dependent inhibition of T-cell lymphoma cells by cotreatment with the mTOR inhibitor everolimus and anticancer drugs. | Investigational new drugs 20120201 |
| Preclincial testing of sorafenib and RAD001 in the Nf(flox/flox) ;DhhCre mouse model of plexiform neurofibroma using magnetic resonance imaging. | Pediatric blood & cancer 20120201 |
| Aprepitant (Emend) significantly increases sirolimus levels in patients undergoing allogeneic hematopoietic SCT. | Bone marrow transplantation 20120201 |
| Cardiac tamponade potentially related to sirolimus following cord blood transplantation. | Bone marrow transplantation 20120201 |
| Sustained clinical safety and efficacy of a biodegradable-polymer coated sirolimus-eluting stent in 'real-world' practice: three-year outcomes of the CREATE (Multi-Center Registry of EXCEL Biodegradable Polymer Drug Eluting Stents) study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201 |
| mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection. | Medical microbiology and immunology 20120201 |
| Effect of different immunosuppressive regimens on the evolution of distinct metabolic parameters: evidence from the Symphony study. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120201 |
| [Sirolimus-eluting stent displaced fracture: case report and review of the literature]. | Annales de cardiologie et d'angeiologie 20120201 |
| Preparation and influencing factors of sirolimus liposome by supercritical fluid. | Artificial cells, blood substitutes, and immobilization biotechnology 20120201 |
| [PI3K-AKT-mTOR pathway and cancer]. | Bulletin du cancer 20120201 |
| mTOR inhibition and erythropoiesis: microcytosis or anaemia? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120201 |
| An international expanded-access programme of everolimus: addressing safety and efficacy in patients with metastatic renal cell carcinoma who progress after initial vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapy. | European journal of cancer (Oxford, England : 1990) 20120201 |
| [Intermittent fever under iatrogenic immunosuppression]. | Der Internist 20120201 |
| Mammalian target of rapamycin (mTOR) inhibitors slow skin carcinogenesis, but impair wound healing. | The British journal of dermatology 20120201 |
| mTOR as a therapeutic target in patients with gastric cancer. | International journal of cancer 20120201 |
| mTOR is a selective effector of the radiation therapy response in androgen receptor-positive prostate cancer. | Endocrine-related cancer 20120201 |
| EGFR- and AKT-mediated reduction in PTEN expression contributes to tyrphostin resistance and is reversed by mTOR inhibition in endometrial cancer cells. | Molecular and cellular biochemistry 20120201 |
| Antirestenotic mechanisms of everolimus on human coronary artery smooth muscle cells: inhibition of human coronary artery smooth muscle cell proliferation, but not migration. | Journal of cardiovascular pharmacology 20120201 |
| Rapamycin provides a therapeutic option through inhibition of mTOR signaling in chronic myelogenous leukemia. | Oncology reports 20120201 |
| Activation of mTOR by human T-cell leukemia virus type 1 Tax is important for the transformation of mouse T cells to interleukin-2-independent growth. | Cancer science 20120201 |
| Five-year clinical outcome after primary stenting of totally occluded native coronary arteries: a randomised comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions (PRISON II study). | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120201 |
| Pharmacokinetic analysis after implantation of everolimus-eluting self-expanding stents in the peripheral vasculature. | Journal of vascular surgery 20120201 |
| Insulin-induced mTOR activity exhibits anti-hepatitis C virus activity. | Molecular medicine reports 20120201 |
| Clinical outcomes in kidney transplant recipients receiving long-term therapy with inhibitors of the mammalian target of rapamycin. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120201 |
| Focal adhesion kinase governs cardiac concentric hypertrophic growth by activating the AKT and mTOR pathways. | Journal of molecular and cellular cardiology 20120201 |
| Differential mTOR and ERK pathway utilization by effector CD4 T cells suggests combinatorial drug therapy of arthritis. | Clinical immunology (Orlando, Fla.) 20120201 |
| Novel role of c-jun N-terminal kinase in regulating the initiation of cap-dependent translation. | International journal of oncology 20120201 |
| Vascular disruption in combination with mTOR inhibition in renal cell carcinoma. | Molecular cancer therapeutics 20120201 |
| Gene expression profile in response to doxorubicin-rapamycin combined treatment of HER-2-overexpressing human mammary epithelial cell lines. | Molecular cancer therapeutics 20120201 |
| Successful and cost-efficient replacement of immunoassays by tandem mass spectrometry for the quantification of immunosuppressants in the clinical laboratory. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120201 |
| Sorafenib and Mek inhibition is synergistic in medullary thyroid carcinoma in vitro. | Endocrine-related cancer 20120201 |
| Tuberous sclerosis complex-associated angiomyolipomas: focus on mTOR inhibition. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20120201 |
| Everolimus: in patients with subependymal giant cell astrocytoma associated with tuberous sclerosis complex. | Paediatric drugs 20120201 |
| Tregs: application for solid-organ transplantation. | Current opinion in organ transplantation 20120201 |
| Calorie restriction and rapamycin inhibit MMTV-Wnt-1 mammary tumor growth in a mouse model of postmenopausal obesity. | Endocrine-related cancer 20120201 |
| New advances in the diagnosis and treatment of autoimmune lymphoproliferative syndrome. | Current opinion in pediatrics 20120201 |
| Targeting protein synthesis in a Myc/mTOR-driven model of anorexia-cachexia syndrome delays its onset and prolongs survival. | Cancer research 20120201 |
| Major response to everolimus in melanoma with acquired imatinib resistance. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120201 |
| Randomized comparison of everolimus-eluting versus bare-metal stents in patients with critical limb ischemia and infrapopliteal arterial occlusive disease. | Journal of vascular surgery 20120201 |
| Mammalian target of rapamycin (mTOR) inhibition reduces cerebral vasospasm following a subarachnoid hemorrhage injury in canines. | Experimental neurology 20120201 |
| Rhes, a striatal-enriched small G protein, mediates mTOR signaling and L-DOPA-induced dyskinesia. | Nature neuroscience 20120201 |
| The risk of skin rash and stomatitis with the mammalian target of rapamycin inhibitor temsirolimus: a systematic review of the literature and meta-analysis. | European journal of cancer (Oxford, England : 1990) 20120201 |
| Everolimus in metastatic renal cell carcinoma: Subgroup analysis of patients with 1 or 2 previous vascular endothelial growth factor receptor-tyrosine kinase inhibitor therapies enrolled in the phase III RECORD-1 study. | European journal of cancer (Oxford, England : 1990) 20120201 |
| L-leucine alters pancreatic β-cell differentiation and function via the mTor signaling pathway. | Diabetes 20120201 |
| Rapalogs in viral cancers. | Expert opinion on investigational drugs 20120201 |
| The CXCR4 antagonist POL5551 is equally effective as sirolimus in reducing neointima formation without impairing re-endothelialisation. | Thrombosis and haemostasis 20120201 |
| Intrabiliary rapamycin may slow progression of primary sclerosing cholangitis. | Alimentary pharmacology & therapeutics 20120201 |
| Stimulation of autophagy by rapamycin protects neurons from remote degeneration after acute focal brain damage. | Autophagy 20120201 |
| miR-376b controls starvation and mTOR inhibition-related autophagy by targeting ATG4C and BECN1. | Autophagy 20120201 |
| [Hepatocellular carcinoma: what's new?]. | Deutsche medizinische Wochenschrift (1946) 20120201 |
| Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy. | Autophagy 20120201 |
| Roles of the mammalian target of rapamycin, mTOR, in controlling ribosome biogenesis and protein synthesis. | Biochemical Society transactions 20120201 |
| Target of rapamcyin (TOR)-based therapeutics for cardiomyopathy: insights from zebrafish genetics. | Cell cycle (Georgetown, Tex.) 20120201 |
| Increasingly aggressive endovascular management of tibial artery occlusive disease. | Journal of vascular surgery 20120201 |
| Creating biodegradable-polymer drug-eluting stents: shortening the duration of polymer and dual antiplatelet therapy while lengthening the follow-up. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120201 |
| Deregulated mTOR-mediated translation in intellectual disability. | Progress in neurobiology 20120201 |
| Mechanism of edge restenosis after sirolimus-eluting stent implantation. | The Journal of invasive cardiology 20120201 |
| Topical 0.1% rapamycin for angiofibromas in paediatric patients with tuberous sclerosis: a pilot study of four patients. | The Australasian journal of dermatology 20120201 |
| Long-term outcome of conversion to sirolimus monotherapy after liver transplant. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20120201 |
| Sirolimus-eluting stents for the treatment of infrapopliteal arteries in chronic limb ischemia: long-term clinical and angiographic follow-up. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20120201 |
| Prime time for infrapopliteal drug-eluting stents? | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20120201 |
| Advantages of novel BioMimeTM Sirolimus Eluting Coronary Stent system. Moving towards biomimicry. | Minerva cardioangiologica 20120201 |
| Comparison of early and late conversion of sirolimus in experimental model of chronic cyclosporine nephropathy. | Journal of Korean medical science 20120201 |
| Surgical treatment of entrapped intravascular ultrasonography catheter. | General thoracic and cardiovascular surgery 20120201 |
| Side branch fractional flow reserve measurements after main vessel stenting: a Nordic-Baltic Bifurcation Study III substudy. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120201 |
| One-year outcomes of patients with the zotarolimus-eluting coronary stent: RESOLUTE International Registry. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120201 |
| Calcified in-stent restenosis: a rare cause of dilation failure requiring rotational atherectomy. | Circulation. Cardiovascular interventions 20120201 |
| OCT-verified neointimal hyperplasia is increased at fracture site in drug-eluting stents. | JACC. Cardiovascular imaging 20120201 |
| Automated image analysis of nuclear shape: what can we learn from a prematurely aged cell? | Aging 20120201 |
| Molecular imaging of drug-eluting coronary stents: method development, optimization and selected applications. | Journal of mass spectrometry : JMS 20120201 |
| Long-term comparison of everolimus- and sirolimus-eluting stents in patients with acute coronary syndromes. | JACC. Cardiovascular interventions 20120201 |
| No evidence of 'obesity paradox' after treatment with drug-eluting stents in a routine clinical practice: results from the prospective multicenter German DES.DE (German Drug-Eluting Stent) Registry. | JACC. Cardiovascular interventions 20120201 |
| [Immunogenetic diagnosis of large granular lymphocytic leukemia and therapy by sirolimus]. | Zhongguo shi yan xue ye xue za zhi 20120201 |
| [Effect of granulocyte-macrophage colony-stimulating factor on the mammalian target of sirolimus signaling pathway in the wound of rat]. | Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20120201 |
| [Sirolimus use in heart transplantation recipients with chronic renal dysfunction]. | Zhonghua xin xue guan bing za zhi 20120201 |
| Target of rapamycin (TOR)-based therapy for cardiomyopathy: evidence from zebrafish and human studies. | Trends in cardiovascular medicine 20120201 |
| Very late stent thrombosis and late target lesion revascularization after sirolimus-eluting stent implantation: five-year outcome of the j-Cypher Registry. | Circulation 20120131 |
| Very late stent thrombosis and late target lesion revascularization: no end in sight. | Circulation 20120131 |
| Rapamycin inhibits osteolysis and improves survival in a model of experimental bone metastases. | Cancer letters 20120128 |
| Saccharomyces cerevisiae Tel2 plays roles in TORC signaling and telomere maintenance that can be mutationally separated. | Biochemical and biophysical research communications 20120127 |
| Response to 'Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is...'. | International journal of cardiology 20120126 |
| Influenza virus polymerase confers independence of the cellular cap-binding factor eIF4E for viral mRNA translation. | Virology 20120120 |
| Rapamycin and glucose-target of rapamycin (TOR) protein signaling in plants. | The Journal of biological chemistry 20120120 |
| Targeted therapies for renal cell carcinoma: review of adverse event management strategies. | Journal of the National Cancer Institute 20120118 |
| Optimization of rapamycin-loaded acetalated dextran microparticles for immunosuppression. | International journal of pharmaceutics 20120117 |
| Activation of mTOR/p70S6 kinase by ANG II inhibits insulin-stimulated endothelial nitric oxide synthase and vasodilation. | American journal of physiology. Endocrinology and metabolism 20120115 |
| Leucine and arginine regulate trophoblast motility through mTOR-dependent and independent pathways in the preimplantation mouse embryo. | Developmental biology 20120115 |
| Impact of early conversion from tacrolimus to sirolimus on chronic allograft changes in kidney recipients on rapid steroid withdrawal. | Transplantation 20120115 |
| Rapamycin combined with TGF-β converts human invariant NKT cells into suppressive Foxp3+ regulatory cells. | Journal of immunology (Baltimore, Md. : 1950) 20120115 |
| Facial angiofibromas treated with topical rapamycin: an excellent choice with fast response. | Dermatology online journal 20120115 |
| Comparison of drug-eluting versus bare-metal stent implantation in ST-elevation myocardial infarction patients with renal insufficiency: results from the national registry in Korea. | International journal of cardiology 20120112 |
| Dual mTORC1/mTORC2 inhibition diminishes Akt activation and induces Puma-dependent apoptosis in lymphoid malignancies. | Blood 20120112 |
| CB2 cannabinoid receptors promote neural progenitor cell proliferation via mTORC1 signaling. | The Journal of biological chemistry 20120106 |
| Hyperpolarized 13C MR spectroscopic imaging can be used to monitor Everolimus treatment in vivo in an orthotopic rodent model of glioblastoma. | NeuroImage 20120102 |
| Rictor-dependent AKT activation and inhibition of urothelial carcinoma by rapamycin. | Urologic oncology 20120101 |
| mTOR pathway inhibition in renal cell carcinoma. | Urologic oncology 20120101 |
| An update on targeted therapy in metastatic renal cell carcinoma. | Urologic oncology 20120101 |
| Morphological and functional evaluation of the bioresorption of the bioresorbable everolimus-eluting vascular scaffold using IVUS, echogenicity and vasomotion testing at two year follow-up: a patient level insight into the ABSORB A clinical trial. | The international journal of cardiovascular imaging 20120101 |
| Reproducibility of Shin's method for necrotic core and calcium content in atherosclerotic coronary lesions treated with bioresorbable everolimus-eluting vascular scaffolds using volumetric intravascular ultrasound radiofrequency-based analysis. | The international journal of cardiovascular imaging 20120101 |
| Pharmacokinetics and pharmacodynamics of mycophenolate sodium (EC-MPS) co-administered with cyclosporine in the early-phase post-kidney transplantation. | Clinical transplantation 20120101 |
| Long-term effects on renal function of dose-reduced calcineurin inhibitor and sirolimus in cardiac transplant patients. | Clinical transplantation 20120101 |
| The effect of mTOR inhibition alone or combined with MEK inhibitors on brain metastasis: an in vivo analysis in triple-negative breast cancer models. | Breast cancer research and treatment 20120101 |
| A case of subacute thrombosis associated with clopidogrel resistance after implantation of a zotarolimus-eluting stent. | Heart and vessels 20120101 |
| Temsirolimus in combination with carboplatin and paclitaxel in patients with advanced solid tumors: a NCIC-CTG, phase I, open-label dose-escalation study (IND 179). | Annals of oncology : official journal of the European Society for Medical Oncology 20120101 |
| Third in-stent restenosis in sirolimus eluting stents: predictors of the next restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20120101 |
| Pathological features of in-stent restenosis after sirolimus-eluting stent versus bare metal stent placement. | Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology 20120101 |
| Rapamycin decreases survivin expression to induce NSCLC cell apoptosis under hypoxia through inhibiting HIF-1α induction. | Molecular biology reports 20120101 |
| Sirolimus-based regimen is associated with decreased expression of glomerular vascular endothelial growth factor. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120101 |
| Usefulness of preclinical models for assessing the efficacy of late-life interventions for sarcopenia. | The journals of gerontology. Series A, Biological sciences and medical sciences 20120101 |
| Evaluating rational non-cross-resistant combination therapy in advanced clear cell renal cell carcinoma: combined mTOR and AKT inhibitor therapy. | Cancer chemotherapy and pharmacology 20120101 |
| Safety and efficacy of temsirolimus in heavily pretreated patients with metastatic renal cell carcinoma. | Acta oncologica (Stockholm, Sweden) 20120101 |
| The use of sirolimus should be restricted in liver transplantation. | Journal of hepatology 20120101 |
| Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis Type 1. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20120101 |
| Caloric restriction and chronic inflammatory diseases. | Oral diseases 20120101 |
| Sirolimus--it doesn't deserve its bad Rap(a). | Journal of hepatology 20120101 |
| Rapamycin reduces oxidative stress in frataxin-deficient yeast cells. | Mitochondrion 20120101 |
| Is advanced hepatocellular carcinoma amenable of cure by liver transplantation with sorafenib as a neoadjuvant approach plus m-TOR inhibitors monotherapy? | Journal of surgical oncology 20120101 |
| Erythropoietin mediated bone formation is regulated by mTOR signaling. | Journal of cellular biochemistry 20120101 |
| S6K inhibition renders cardiac protection against myocardial infarction through PDK1 phosphorylation of Akt. | The Biochemical journal 20120101 |
| Neuronal and glia abnormalities in Tsc1-deficient forebrain and partial rescue by rapamycin. | Neurobiology of disease 20120101 |
| GADD34 mediates cytoprotective autophagy in mutant huntingtin expressing cells via the mTOR pathway. | Experimental cell research 20120101 |
| CD40 blockade combines with CTLA4Ig and sirolimus to produce mixed chimerism in an MHC-defined rhesus macaque transplant model. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120101 |
| Efficacy and safety of sorafenib in combination with mammalian target of rapamycin inhibitors for recurrent hepatocellular carcinoma after liver transplantation. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120101 |
| Everolimus-eluting stents for treatment of chronic total coronary occlusions. | Clinical research in cardiology : official journal of the German Cardiac Society 20120101 |
| Clinical long-term outcome after implantation of titanium nitride-oxide coated stents compared with paclitaxel- or sirolimus-eluting stents: propensity-score matched analysis. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101 |
| Four-year clinical follow-up of the ABSORB everolimus-eluting bioresorbable vascular scaffold in patients with de novo coronary artery disease: the ABSORB trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101 |
| Campylobacter jejuni induces colitis through activation of mammalian target of rapamycin signaling. | Gastroenterology 20120101 |
| Lack of amino acids in mouse hepatocytes in culture induces the selection of preneoplastic cells. | Cellular signalling 20120101 |
| Sirolimus-based immunosuppression in liver transplantation for hepatocellular carcinoma: a meta-analysis. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20120101 |
| Rapamycin causes upregulation of autophagy and impairs islets function both in vitro and in vivo. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120101 |
| Pharmacokinetic drug interaction between AEE788 and RAD001 causing thrombocytopenia in patients with glioblastoma. | Cancer chemotherapy and pharmacology 20120101 |
| Butyrolactone derivative 3-benzyl-5-((2-nitrophenoxy) methyl)-dihydrofuran-2(3H)-one protects against amyloid-β peptides-induced cytotoxicity in PC12 cells. | Journal of Alzheimer's disease : JAD 20120101 |
| A theoretical model to characterize the drug release behavior of drug-eluting stents with durable polymer matrix coating. | Journal of biomedical materials research. Part A 20120101 |
| Effective everolimus treatment of inoperable, life-threatening subependymal giant cell astrocytoma and intractable epilepsy in a patient with tuberous sclerosis complex. | European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society 20120101 |
| Impact of calcification on the long-term outcomes of sirolimus-eluting stent implantation: subanalysis of the Cypher Post-Marketing Surveillance Registry. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Production of 3-hydroxypropionic acid through propionaldehyde dehydrogenase PduP mediated biosynthetic pathway in Klebsiella pneumoniae. | Bioresource technology 20120101 |
| Differential regulation of simultaneous antitumor and alloreactive CD8(+) T-cell responses in the same host by rapamycin. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20120101 |
| Is there any place for macrolides in mood disorders? | Medical hypotheses 20120101 |
| Phase II trial of temsirolimus in children with high-grade glioma, neuroblastoma and rhabdomyosarcoma. | European journal of cancer (Oxford, England : 1990) 20120101 |
| Inhibition of mTOR by rapamycin in the amygdala or hippocampus impairs formation and reconsolidation of inhibitory avoidance memory. | Neurobiology of learning and memory 20120101 |
| Effect of early conversion from CNI to sirolimus on outcomes in kidney transplant recipients with allograft dysfunction. | Journal of nephrology 20120101 |
| Three-year follow-up of sirolimus-eluting stents vs. bare metal stents for acute myocardial infarction. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Rapamycin induces Bad phosphorylation in association with its resistance to human lung cancer cells. | Molecular cancer therapeutics 20120101 |
| The PTPN11 loss-of-function mutation Q510E-Shp2 causes hypertrophic cardiomyopathy by dysregulating mTOR signaling. | American journal of physiology. Heart and circulatory physiology 20120101 |
| Current development of the second generation of mTOR inhibitors as anticancer agents. | Chinese journal of cancer 20120101 |
| Rapamycin inhibiting Jurkat T cells viability through changing mRNA expression of serine/threonine protein phosphatase 2A. | Transplant immunology 20120101 |
| RhoA and Rho kinase mediate cyclosporine A and sirolimus-induced barrier tightening in renal proximal tubular cells. | The international journal of biochemistry & cell biology 20120101 |
| Phase II study of the mammalian target of rapamycin inhibitor ridaforolimus in patients with advanced bone and soft tissue sarcomas. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120101 |
| From node to pathway blockade: lessons learned from targeting mammalian target of rapamycin. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20120101 |
| Rapamycin inhibits osteoclast formation in giant cell tumor of bone through the C/EBPβ - MafB axis. | Journal of molecular medicine (Berlin, Germany) 20120101 |
| Temsirolimus, an mTOR inhibitor, in combination with lower-dose clofarabine as salvage therapy for older patients with acute myeloid leukaemia: results of a phase II GIMEMA study (AML-1107). | British journal of haematology 20120101 |
| The type 1 insulin-like growth factor receptor (IGF-IR) pathway is mandatory for the follistatin-induced skeletal muscle hypertrophy. | Endocrinology 20120101 |
| Acquired Omenn-like syndrome, a novel posttransplant autoaggression syndrome reversed by rapamycin. | Clinical and vaccine immunology : CVI 20120101 |
| Spatial distribution and temporal evolution of scattering centers by optical coherence tomography in the poly(L-lactide) backbone of a bioresorbable vascular scaffold. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| A randomized, dose-escalation study of subconjunctival and intravitreal injections of sirolimus in patients with diabetic macular edema. | Ophthalmology 20120101 |
| Exercise modulates microRNAs that affect the PTEN/mTOR pathway in rats after spinal cord injury. | Experimental neurology 20120101 |
| Mammalian target of rapamycin: a signaling kinase for every aspect of cellular life. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Biochemical and pharmacological inhibition of mTOR by rapamycin and an ATP-competitive mTOR inhibitor. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Evaluation of rapamycin-induced cell death. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Evaluation of mTOR-regulated mRNA translation. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| A genome-wide RNAi screen for polypeptides that alter rpS6 phosphorylation. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Quantitative visualization of autophagy induction by mTOR inhibitors. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Expanding human T regulatory cells with the mTOR-inhibitor rapamycin. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Rapamycin-induced enhancement of vaccine efficacy in mice. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Exploring functional in vivo consequences of the selective genetic ablation of mTOR signaling in T helper lymphocytes. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Evaluating the therapeutic potential of mTOR inhibitors using mouse genetics. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Inhibition of PI3K-Akt-mTOR signaling in glioblastoma by mTORC1/2 inhibitors. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Assessing the function of mTOR in human embryonic stem cells. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Tissue-specific ablation of Tsc1 in pancreatic beta-cells. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| A mouse model of diet-induced obesity and insulin resistance. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Rapamycin as immunosuppressant in murine transplantation model. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Development of ATP-competitive mTOR inhibitors. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Cre8™ coronary stent: preclinical in vivo assessment of a new generation polymer-free DES with Amphilimus™ formulation. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101 |
| Sirolimus-eluting stent vs. everolimus-eluting stent for coronary intervention in patients on chronic hemodialysis. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| In vivo optical coherence tomography of very late drug-eluting stent thrombosis compared with late in-stent restenosis. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Preconditioning donor with a combination of tacrolimus and rapamacyn to decrease ischaemia-reperfusion injury in a rat syngenic kidney transplantation model. | Clinical and experimental immunology 20120101 |
| Tacrolimus versus cyclosporine for early steroid withdrawal after renal transplantation. | Journal of nephrology 20120101 |
| mTOR inhibitor-associated proteinuria in kidney transplant recipients. | Transplantation reviews (Orlando, Fla.) 20120101 |
| Functional characterization of glycine N-methyltransferase and its interactive protein DEPDC6/DEPTOR in hepatocellular carcinoma. | Molecular medicine (Cambridge, Mass.) 20120101 |
| An unusual cause of cancer mimicry following liver transplantation. | Annals of hepatology 20120101 |
| Rapamycin activates autophagy in Hutchinson-Gilford progeria syndrome: implications for normal aging and age-dependent neurodegenerative disorders. | Autophagy 20120101 |
| Sex-specific benefits of sirolimus-eluting stent on long-term outcomes in patients with ST-elevation myocardial infarction undergoing primary percutaneous coronary intervention: insights from the Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarction Study trial. | American heart journal 20120101 |
| Drug-eluting stents at a crossroads: the good, the bad and the ugly. | Future cardiology 20120101 |
| A double whammy for aging? Rapamycin extends lifespan and inhibits cancer in inbred female mice. | Cell cycle (Georgetown, Tex.) 20120101 |
| Repetita iuvant (repeating helps): why another paper on a new stent is important. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101 |
| Five-year clinical follow-up from the MISSION! Intervention Study: sirolimus-eluting stent versus bare metal stent implantation in patients with ST-segment elevation myocardial infarction, a randomised controlled trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101 |
| Predictors of early and late outcomes after everolimus and paclitaxel-eluting coronary stents. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20120101 |
| Intravascular ultrasound assessment of postprocedural incomplete stent apposition. | The Journal of invasive cardiology 20120101 |
| mTOR as a target of everolimus in refractory/relapsed Hodgkin lymphoma. | Current medicinal chemistry 20120101 |
| The sirolimus-eluting Cypher Select coronary stent for the treatment of bare-metal and drug-eluting stent restenosis: insights from the e-SELECT (Multicenter Post-Market Surveillance) registry. | JACC. Cardiovascular interventions 20120101 |
| Validation of an LC-MS/MS method to determine five immunosuppressants with deuterated internal standards including MPA. | BMC clinical pharmacology 20120101 |
| [Drug-induced pneumonitis due to sirolimus: an interaction with atorvastatin?]. | Revue des maladies respiratoires 20120101 |
| Rapamycin-induced tumor vasculature remodeling in rhabdomyosarcoma xenografts increases the effectiveness of adjuvant ionizing radiation. | Journal of pediatric surgery 20120101 |
| A novel application of topical rapamycin formulation, an inhibitor of mTOR, for patients with hypomelanotic macules in tuberous sclerosis complex. | Archives of dermatology 20120101 |
| An adaptive group sequential phase II design to compare treatments for survival endpoints in rare patient entities. | Journal of biopharmaceutical statistics 20120101 |
| Reversible acute encephalopathy with mutism, induced by calcineurin inhibitors after renal transplantation. | Journal of nephrology 20120101 |
| HIV-1 promotes renal tubular epithelial cell protein synthesis: role of mTOR pathway. | PloS one 20120101 |
| [Immunosuppression in kidney donors with rapamycin and tacrolimus. Proinflammatory cytokine expression]. | Medicina 20120101 |
| Additive effectiveness of everolimus plus tamoxifen therapy in treatment of encapsulating peritoneal sclerosis. | Renal failure 20120101 |
| Randomized comparison of the efficacy and safety of zotarolimus-eluting stents vs. sirolimus-eluting stents for percutaneous coronary intervention in chronic total occlusion--CAtholic Total Occlusion Study (CATOS) trial. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Paclitaxel resistance is associated with switch from apoptotic to autophagic cell death in MCF-7 breast cancer cells. | Cell death & disease 20120101 |
| A new path to longevity. | Scientific American 20120101 |
| Everolimus with reduced-dose cyclosporine versus full-dose cyclosporine and mycophenolate in de novo renal transplant patients: a 2-year single-center experience. | Transplantation proceedings 20120101 |
| Sirolimus-induced pneumonitis after renal transplantation: a single-center experience. | Transplantation proceedings 20120101 |
| Trends in the use of immunosuppressive agents by outpatients after renal transplantation at a medical center in southern Taiwan. | Transplantation proceedings 20120101 |
| Trends in maintenance immunosuppressive drugs used in taiwanese kidney transplant recipients: an analysis of the national health insurance research database. | Transplantation proceedings 20120101 |
| Statins and stent thrombosis. | Swiss medical weekly 20120101 |
| First-in-man study of simvastatin-eluting stent in de novo coronary lesions: the SIMVASTENT study. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| TSC1/2 signaling complex is essential for peripheral naïve CD8+ T cell survival and homeostasis in mice. | PloS one 20120101 |
| Resveratrol inhibits inflammatory responses via the mammalian target of rapamycin signaling pathway in cultured LPS-stimulated microglial cells. | PloS one 20120101 |
| Short- and long-term major adverse cardiac events in patients undergoing percutaneous coronary intervention with stenting for acute myocardial infarction complicated by cardiogenic shock. | Cardiology 20120101 |
| Bullous pemphigoid in a transplant recipient: is this a sign of allograft rejection? | European journal of dermatology : EJD 20120101 |
| Impact of positive peri-stent vascular remodeling after sirolimus-eluting and paclitaxel-eluting stent implantation on 5-year clinical outcomes: intravascular ultrasound analysis from the Poststent Optimal Stent Expansion Trial multicenter randomized trial. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Steve Jobs's cancer. Pancreatic neuroendocrine tumors are becoming more common (the bad news) and also more treatable (the good news). | Harvard health letter 20120101 |
| Antitumor activities of ATP-competitive inhibitors of mTOR in colon cancer cells. | BMC cancer 20120101 |
| Delivering hydrophilic and hydrophobic chemotherapeutics simultaneously by magnetic mesoporous silica nanoparticles to inhibit cancer cells. | International journal of nanomedicine 20120101 |
| Effects of STAT3 gene silencing and rapamycin on apoptosis in hepatocarcinoma cells. | International journal of medical sciences 20120101 |
| Histological spectrum of pulmonary manifestations in kidney transplant recipients on sirolimus inclusive immunosuppressive regimens. | Diagnostic pathology 20120101 |
| Delayed mTOR inhibition with low dose of everolimus reduces TGFβ expression, attenuates proteinuria and renal damage in the renal mass reduction model. | PloS one 20120101 |
| Activation of PI3K/AKT and MAPK pathway through a PDGFRβ-dependent feedback loop is involved in rapamycin resistance in hepatocellular carcinoma. | PloS one 20120101 |
| Clinical outcomes after treatment of multiple lesions with zotarolimus-eluting versus sirolimus-eluting coronary stents (a SORT OUT III substudy). | BMC cardiovascular disorders 20120101 |
| [Metastatic breast cancer. Everolimus --a drug delays the progression of the tumor]. | Perspective infirmiere : revue officielle de l'Ordre des infirmieres et infirmiers du Quebec 20120101 |
| The 'Harmonizing Optimal Strategy for Treatment of coronary artery stenosis - sAfety & effectiveneSS of drug-elUting stents & antiplatelet REgimen' (HOST-ASSURE) trial: study protocol for a randomized controlled trial. | Trials 20120101 |
| A case of Takayasu arteritis with repeated coronary artery restenosis after drug-eluting stent implantation successfully treated with a combination of steroids. | Internal medicine (Tokyo, Japan) 20120101 |
| Conversion from everolimus with low-exposure cyclosporine to everolimus with mycophenolate sodium maintenance therapy in kidney transplant recipients: a randomized, open-label multicenter study. | Annals of transplantation 20120101 |
| Rapamycin ameliorates kidney fibrosis by inhibiting the activation of mTOR signaling in interstitial macrophages and myofibroblasts. | PloS one 20120101 |
| Targeting mTOR pathways in human malignancies. | Current pharmaceutical design 20120101 |
| Autophagy-lysosomal pathway is involved in lipid degradation in rat liver. | Physiological research 20120101 |
| Growth hormone improves growth retardation induced by rapamycin without blocking its antiproliferative and antiangiogenic effects on rat growth plate. | PloS one 20120101 |
| Ex-vivo expanded baboon CD4+ CD25 Hi Treg cells suppress baboon anti-pig T and B cell immune response. | Xenotransplantation 20120101 |
| Rapamycin conditioning of dendritic cells differentiated from human ES cells promotes a tolerogenic phenotype. | Journal of biomedicine & biotechnology 20120101 |
| Rapamycin sensitive ROS formation and Na(+)/H(+) exchanger activity in dendritic cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101 |
| Vascular compliance changes of the coronary vessel wall after bioresorbable vascular scaffold implantation in the treated and adjacent segments. | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Outcomes of patients treated with the everolimus-eluting stent versus the zotarolimus eluting stent in a consecutive cohort of patients at a tertiary medical center. | Vascular health and risk management 20120101 |
| Inflammation-driven reprogramming of CD4+ Foxp3+ regulatory T cells into pathogenic Th1/Th17 T effectors is abrogated by mTOR inhibition in vivo. | PloS one 20120101 |
| Novel synergistic antitumor effects of rapamycin with bortezomib on hepatocellular carcinoma cells and orthotopic tumor model. | BMC cancer 20120101 |
| [Neuroendocrine tumors: the age of targeted therapies]. | Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion 20120101 |
| Low dose rapamycin exacerbates autoimmune experimental uveitis. | PloS one 20120101 |
| Onychopathy induced by temsirolimus, a mammalian target of rapamycin inhibitor. | Dermatology (Basel, Switzerland) 20120101 |
| Preclinical evaluation of injectable sirolimus formulated with polymeric nanoparticle for cancer therapy. | International journal of nanomedicine 20120101 |
| Simultaneous determination of cyclosporine A, tacrolimus, sirolimus, and everolimus in whole-blood samples by LC-MS/MS. | TheScientificWorldJournal 20120101 |
| Drosophila poly suggests a novel role for the Elongator complex in insulin receptor-target of rapamycin signalling. | Open biology 20120101 |
| Genotype-dependent efficacy of a dual PI3K/mTOR inhibitor, NVP-BEZ235, and an mTOR inhibitor, RAD001, in endometrial carcinomas. | PloS one 20120101 |
| Sirolimus eluting coronary stent implantation in patients on maintenance hemodialysis: the OUCH study (outcome of cypher stent inhemodialysis patients). | Circulation journal : official journal of the Japanese Circulation Society 20120101 |
| Paradoxical effects of rapamycin on experimental house dust mite-induced asthma. | PloS one 20120101 |
| Preparation and in vivo evaluation of liposomal everolimus for lung carcinoma and thyroid carcinoma. | Biological & pharmaceutical bulletin 20120101 |
| Extensive gene-specific translational reprogramming in a model of B cell differentiation and Abl-dependent transformation. | PloS one 20120101 |
| BOLERO-2 - will this change practice in advanced breast cancer? | Breast cancer research : BCR 20120101 |
| Comparative vascular responses three months after paclitaxel and everolimus-eluting stent implantation in streptozotocin-induced diabetic porcine coronary arteries. | Cardiovascular diabetology 20120101 |
| Coronary artery aneurysm after implantation of an endothelial progenitor cell capturing stent. | Kardiologia polska 20120101 |
| Tumor growth effects of rapamycin on human biliary tract cancer cells. | European journal of medical research 20120101 |
| Inhibition of chondrosarcoma growth by mTOR inhibitor in an in vivo syngeneic rat model. | PloS one 20120101 |
| Simultaneous determination of cyclosporine, sirolimus, and tacrolimus in whole blood using liquid chromatography-tandem mass spectrometry. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Autophagy influences maternal mRNA degradation and apoptosis in porcine parthenotes developing in vitro. | The Journal of reproduction and development 20120101 |
| Everolimus enhances gemcitabine-induced cytotoxicity in bladder-cancer cell lines. | Journal of toxicology and environmental health. Part A 20120101 |
| Comparison of long-term clinical outcomes between sirolimus-eluting stents and paclitaxel-eluting stents following rotational atherectomy. | International heart journal 20120101 |
| Occurrence of late acquired peri-stent contrast staining: comparison between sirolimus-eluting stents and everolimus-eluting stents. | International heart journal 20120101 |
| Successful conversion to everolimus after cytomegalovirus infection in a heart transplant recipient. | International heart journal 20120101 |
| A case of pancreatic cancer after heart transplantation. | International heart journal 20120101 |
| Current status and perspectives of targeted therapy in well-differentiated neuroendocrine tumors. | Oncology 20120101 |
| Sunitinib and everolimus in pancreatic neuroendocrine tumors. | Tumori 20120101 |
| Protective role of p70S6K in intestinal ischemia/reperfusion injury in mice. | PloS one 20120101 |
| Sirolimus induced phosphaturia is not caused by inhibition of renal apical sodium phosphate cotransporters. | PloS one 20120101 |
| Mid-term clinical outcomes of ACS and non-ACS patients treated with everolimus-eluting stents. | International heart journal 20120101 |
| Nuclear-cytoplasmic trafficking of NTF2, the nuclear import receptor for the RanGTPase, is subjected to regulation. | PloS one 20120101 |
| BRAFV600E negatively regulates the AKT pathway in melanoma cell lines. | PloS one 20120101 |
| Outcomes with various drug eluting or bare metal stents in patients with diabetes mellitus: mixed treatment comparison analysis of 22,844 patient years of follow-up from randomised trials. | BMJ (Clinical research ed.) 20120101 |
| Rapamycin inhibits proliferation of hemangioma endothelial cells by reducing HIF-1-dependent expression of VEGF. | PloS one 20120101 |
| Impact of rapamycin on peritoneal fibrosis and transport function. | Blood purification 20120101 |
| Rapamycin regulates the expression and activity of Krüppel-like transcription factor 2 in human umbilical vein endothelial cells. | PloS one 20120101 |
| Tolerance induction by exosomes from immature dendritic cells and rapamycin in a mouse cardiac allograft model. | PloS one 20120101 |
| Impact of small molecules immunosuppressants on P-glycoprotein activity and T-cell function. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20120101 |
| Progress in strategies for dosage regimen individualization. | Current topics in medicinal chemistry 20120101 |
| Amino acids and TOR signaling promote prothoracic gland growth and the initiation of larval molts in the tobacco hornworm Manduca sexta. | PloS one 20120101 |
| The mTOR inhibitor rapamycin has limited acute anticonvulsant effects in mice. | PloS one 20120101 |
| [Comparing moderately late results of the application of stents coated with a medicinal antiproliferative agent for the treatment of patients with various forms of coronary heart disease: their efficacy and safety]. | Klinicheskaia meditsina 20120101 |
| The antitumor effect of GDC-0941 alone and in combination with rapamycin in breast cancer cells. | Chemotherapy 20120101 |
| Impact of CYP3A4*1B and CYP3A5*3 polymorphisms on the pharmacokinetics of cyclosporine and sirolimus in renal transplant recipients. | Annals of transplantation 20120101 |
| Inhibition of autophagy contributes to ischemic postconditioning-induced neuroprotection against focal cerebral ischemia in rats. | PloS one 20120101 |
| Flt3L combined with rapamycin promotes cardiac allograft tolerance by inducing regulatory dendritic cells and allograft autophagy in mice. | PloS one 20120101 |
| Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2. | PloS one 20120101 |
| Grape polyphenols inhibit Akt/mammalian target of rapamycin signaling and potentiate the effects of gefitinib in breast cancer. | Nutrition and cancer 20120101 |
| Low-dose oral sirolimus and the risk of menstrual-cycle disturbances and ovarian cysts: analysis of the randomized controlled SUISSE ADPKD trial. | PloS one 20120101 |
| Correcting overall survival for the impact of crossover via a rank-preserving structural failure time (RPSFT) model in the RECORD-1 trial of everolimus in metastatic renal-cell carcinoma. | Journal of biopharmaceutical statistics 20120101 |
| Simultaneous very late stent thrombosis in multiple coronary arteries. | Texas Heart Institute journal 20120101 |
| Everolimus and sirolimus in combination with cyclosporine have different effects on renal metabolism in the rat. | PloS one 20120101 |
| Involvement of phosphatidylinositol 3-kinase/Akt pathway in gemcitabine-induced apoptosis-like cell death in insulinoma cell line INS-1. | Biological & pharmaceutical bulletin 20120101 |
| Nitrogen-responsive regulation of GATA protein family activators Gln3 and Gat1 occurs by two distinct pathways, one inhibited by rapamycin and the other by methionine sulfoximine. | The Journal of biological chemistry 20111230 |
| Nutrient limitations alter cell division control and chromosome segregation through growth-related kinases and phosphatases. | Philosophical transactions of the Royal Society of London. Series B, Biological sciences 20111227 |
| Associations of ABCB1 3435C>T and IL-10-1082G>A polymorphisms with long-term sirolimus dose requirements in renal transplant patients. | Transplantation 20111227 |
| [Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: a 4-year prospective study]. | Zhonghua yi xue za zhi 20111227 |
| The cdk1-cyclin B complex is involved in everolimus triggered resistance in the PC3 prostate cancer cell line. | Cancer letters 20111226 |
| Defining the role of TORC1/2 in multiple myeloma. | Blood 20111222 |
| mTORC1 and mTORC2 differentially regulate homeostasis of neoplastic and non-neoplastic human mast cells. | Blood 20111222 |
| Tor complex 1 controls telomere length by affecting the level of Ku. | Current biology : CB 20111220 |
| Effect of recombinant human SDF-1a on re-endothelialization after sirolimus-eluting stent implantation in rabbit aorta abdominalis. | Life sciences 20111219 |
| Local persistent hypercoagulability after sirolimus-eluting stent implantation in patients with stable angina. | International journal of cardiology 20111215 |
| Rapamycin does not control hemophagocytic lymphohistiocytosis in LCMV-infected perforin-deficient mice. | Pediatric blood & cancer 20111215 |
| Rapamycin for life: a step to immortality. | Cell cycle (Georgetown, Tex.) 20111215 |
| Rapamycin increases lifespan and inhibits spontaneous tumorigenesis in inbred female mice. | Cell cycle (Georgetown, Tex.) 20111215 |
| Late-onset proteinuria after antithymocyte globulin induction and de novo sirolimus monotherapy in kidney transplant recipients. | Transplantation 20111215 |
| Targeting the mTOR/4E-BP pathway in endometrial cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111215 |
| Rapamycin-induced glucose intolerance: hunger or starvation diabetes. | Cell cycle (Georgetown, Tex.) 20111215 |
| Nano-sized drug-loaded micelles deliver payload to lymph node immune cells and prolong allograft survival. | Journal of controlled release : official journal of the Controlled Release Society 20111210 |
| mTOR inhibitor therapy for patients with carcinoid. | Lancet (London, England) 20111210 |
| Everolimus plus octreotide long-acting repeatable for the treatment of advanced neuroendocrine tumours associated with carcinoid syndrome (RADIANT-2): a randomised, placebo-controlled, phase 3 study. | Lancet (London, England) 20111210 |
| Fatty acids suppress autophagic turnover in β-cells. | The Journal of biological chemistry 20111209 |
| A critical role for GluN2B-containing NMDA receptors in cortical development and function. | Neuron 20111208 |
| Polymer drug-eluting stents: is the future biodegradable? | Lancet (London, England) 20111203 |
| Long-term clinical outcomes of biodegradable polymer biolimus-eluting stents versus durable polymer sirolimus-eluting stents in patients with coronary artery disease (LEADERS): 4 year follow-up of a randomised non-inferiority trial. | Lancet (London, England) 20111203 |
| Phosphorylation of eukaryotic translation initiation factor 4B (EIF4B) by open reading frame 45/p90 ribosomal S6 kinase (ORF45/RSK) signaling axis facilitates protein translation during Kaposi sarcoma-associated herpesvirus (KSHV) lytic replication. | The Journal of biological chemistry 20111202 |
| Efficacy of RAD001 (everolimus) against advanced gastric cancer with peritoneal dissemination. | Investigational new drugs 20111201 |
| Long-term stable disease in metastatic renal cell carcinoma: sorafenib sequenced to sunitinib and everolimus: a case study. | Medical oncology (Northwood, London, England) 20111201 |
| Reactivation of tuberculosis during temsirolimus therapy. | Investigational new drugs 20111201 |
| Long-term response with everolimus for metastatic renal cell carcinoma refractory to sunitinib. | Medical oncology (Northwood, London, England) 20111201 |
| Role of the mTOR pathway in LPS-activated monocytes: influence of hypertonic saline. | The Journal of surgical research 20111201 |
| [Immunosuppressive treatments: mechanisms of action and clinical use]. | Nephrologie & therapeutique 20111201 |
| Serial coronary angioscopic findings of drug-eluting stents implanted in a chronic totally occluded lesion. | International journal of cardiology 20111201 |
| Induction of autophagy promotes differentiation of glioma-initiating cells and their radiosensitivity. | International journal of cancer 20111201 |
| 3-Dimensional reconstruction of a bifurcation lesion with double wire after implantation of a second generation everolimus-eluting bioresorbable vascular scaffold. | International journal of cardiology 20111201 |
| Effect of complementary pathway blockade on efficacy of combination enzastaurin and rapamycin. | Head & neck 20111201 |
| Sirolimus for the treatment of complicated vascular anomalies in children. | Pediatric blood & cancer 20111201 |
| Stimulation of cardiomyogenesis of embryonic stem cells by nitric oxide downstream of AMP-activated protein kinase and mTOR signaling pathways. | Stem cells and development 20111201 |
| Sirolimus-eluting stent fracture and aneurysm formation in a young child with a coronary artery bypass graft. | Pediatric cardiology 20111201 |
| Very late stent thrombosis due to DES fracture: description of a case and review of potential causes. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201 |
| Comparison of pharmacokinetics of the limus-eluting stents in Japanese patients. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201 |
| Sirolimus for refractory vascular anomalies. | Pediatric blood & cancer 20111201 |
| Impact of sirolimus, tacrolimus and mycophenolate mofetil on osteoclastogenesis--implications for post-transplantation bone disease. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111201 |
| Immunological aspects of allogeneic and autologous mesenchymal stem cell therapies. | Human gene therapy 20111201 |
| Evaluation of the MassTrak Immunosuppressant XE Kit for the determination of everolimus and cyclosporin A in human whole blood employing isotopically labeled internal standards. | Clinical chemistry and laboratory medicine 20111201 |
| Steroid or tacrolimus withdrawal in renal transplant recipients using sirolimus. | International urology and nephrology 20111201 |
| Inhibitors of mTOR overcome drug resistance from topoisomerase II inhibitors in solid tumors. | Cancer letters 20111201 |
| m-TOR inhibitors: what role in liver transplantation? | Journal of hepatology 20111201 |
| Comparison of zotarolimus- versus everolimus-eluting stents in the treatment of coronary bifurcation lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201 |
| Sequence therapy in patients with metastatic renal cell carcinoma: comparison of common targeted treatment options following failure of receptor tyrosine kinase inhibitors. | European urology 20111201 |
| Inhibition of induced autophagy increases apoptosis of Nara-H cells. | International journal of oncology 20111201 |
| The activation state of the inositol 1,4,5-trisphosphate receptor regulates the velocity of intracellular Ca2+ waves in bovine aortic endothelial cells. | Journal of cellular biochemistry 20111201 |
| Combining mTor inhibitors with rapamycin-resistant T cells: a two-pronged approach to tumor elimination. | Molecular therapy : the journal of the American Society of Gene Therapy 20111201 |
| TGF-β1 mediates sirolimus and cyclosporine A-induced alteration of barrier function in renal epithelial cells via a noncanonical ERK1/2 signaling pathway. | American journal of physiology. Renal physiology 20111201 |
| Three-year clinical outcome with the Endeavor™ zotarolimus-eluting stent in primary percutaneous coronary intervention for ST elevation myocardial infarction: the Endeavor™ primary PCI study (E-PPCI). | Journal of interventional cardiology 20111201 |
| Renal function in children with heart transplantation after switching to CNI-free immunosuppression with everolimus. | Pediatric transplantation 20111201 |
| mTOR: A pathogenic signaling pathway in developmental brain malformations. | Trends in molecular medicine 20111201 |
| Therapeutic value of prenatal rapamycin treatment in a mouse brain model of tuberous sclerosis complex. | Human molecular genetics 20111201 |
| Multi-Link Vision stent vs. first-generation drug-eluting stents: systematic review and meta-analysis. | QJM : monthly journal of the Association of Physicians 20111201 |
| Everolimus in combination with pemetrexed in patients with advanced non-small cell lung cancer previously treated with chemotherapy: a phase I study using a novel, adaptive Bayesian dose-escalation model. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111201 |
| Involvement of the mammalian target of rapamycin signaling in the antidepressant-like effect of group II metabotropic glutamate receptor antagonists. | Neuropharmacology 20111201 |
| Rapamycin protects against middle cerebral artery occlusion induced focal cerebral ischemia in rats. | Behavioural brain research 20111201 |
| Preclinical testing of PI3K/AKT/mTOR signaling inhibitors in a mouse model of ovarian endometrioid adenocarcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111201 |
| Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease. | Journal of applied physiology (Bethesda, Md. : 1985) 20111201 |
| CNI induced Th17/Treg imbalance and susceptibility to renal dysfunction in renal transplantation. | International immunopharmacology 20111201 |
| Performance of everolimus-eluting versus paclitaxel-eluting coronary stents in small vessels: results from the SPIRIT III and SPIRIT IV clinical trials. | Journal of interventional cardiology 20111201 |
| Expression of yeast high mobility group protein HMO1 is regulated by TOR signaling. | Gene 20111201 |
| [Lymphangioleiomyomatosis: new therapeutic approaches]. | Archivos de bronconeumologia 20111201 |
| Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma. | The Journal of investigative dermatology 20111201 |
| Pregnancy under everolimus-based immunosuppression. | Transplant international : official journal of the European Society for Organ Transplantation 20111201 |
| SYNTAX score and Clinical SYNTAX score as predictors of very long-term clinical outcomes in patients undergoing percutaneous coronary interventions: a substudy of SIRolimus-eluting stent compared with pacliTAXel-eluting stent for coronary revascularization (SIRTAX) trial. | European heart journal 20111201 |
| Do wound complications or lymphoceles occur more often in solid organ transplant recipients on mTOR inhibitors? A systematic review of randomized controlled trials. | Transplant international : official journal of the European Society for Organ Transplantation 20111201 |
| Late withdrawal of calcineurin inhibitors and switch to mTOR inhibitors--beneficial or too late? | Pediatric transplantation 20111201 |
| Integration of diffusion-weighted MRI data and a simple mathematical model to predict breast tumor cellularity during neoadjuvant chemotherapy. | Magnetic resonance in medicine 20111201 |
| Comparison of zotarolimus-eluting stents versus sirolimus-eluting stents versus paclitaxel-eluting stents for primary percutaneous coronary intervention in patients with ST-elevation myocardial infarction: results from the Korean Multicentre Endeavor (KOMER) acute myocardial infarction (AMI) trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201 |
| Focused ultrasound-mediated drug delivery from microbubbles reduces drug dose necessary for therapeutic effect on neointima formation--brief report. | Arteriosclerosis, thrombosis, and vascular biology 20111201 |
| Enhanced delivery of rapamycin by V156K-apoA-I high-density lipoprotein inhibits cellular proatherogenic effects and senescence and promotes tissue regeneration. | The journals of gerontology. Series A, Biological sciences and medical sciences 20111201 |
| Air-liquid biofilm formation is dependent on ammonium depletion in a Saccharomyces cerevisiae flor strain. | Yeast (Chichester, England) 20111201 |
| Neuronal Nogo-A regulates glutamate receptor subunit expression in hippocampal neurons. | Journal of neurochemistry 20111201 |
| Chromogranin A and neuron-specific enolase as prognostic markers in patients with advanced pNET treated with everolimus. | The Journal of clinical endocrinology and metabolism 20111201 |
| Rapamycin reduces reactive oxygen species in cultured human corneal endothelial cells. | Current eye research 20111201 |
| Targeted therapy in sarcomas: mammalian target of rapamycin inhibitors from bench to bedside. | Expert opinion on investigational drugs 20111201 |
| Rapamycin attenuates airway hyperreactivity, goblet cells, and IgE in experimental allergic asthma. | Journal of immunology (Baltimore, Md. : 1950) 20111201 |
| The metabolic and toxicological considerations for mTOR inhibitors in the treatment of hepatocarcinoma. | Expert opinion on drug metabolism & toxicology 20111201 |
| Comprehensive intravascular ultrasound assessment of stent area and its impact on restenosis and adverse cardiac events in 403 patients with unprotected left main disease. | Circulation. Cardiovascular interventions 20111201 |
| Infantile hemangioma research: looking backward and forward. | The Journal of investigative dermatology 20111201 |
| Expression pattern and functions of autophagy-related gene atg5 in zebrafish organogenesis. | Autophagy 20111201 |
| Kinetic nomograms assist individualization of drug regimens. | Clinical pharmacokinetics 20111201 |
| Sirolimus in solid organ transplantation: current therapies and new frontiers. | Immunotherapy 20111201 |
| Is there a critical period for mossy fiber sprouting in a mouse model of temporal lobe epilepsy? | Epilepsia 20111201 |
| Autophagy in atherosclerosis: a potential drug target for plaque stabilization. | Arteriosclerosis, thrombosis, and vascular biology 20111201 |
| TFEB, a novel mTORC1 effector implicated in lysosome biogenesis, endocytosis and autophagy. | Cell cycle (Georgetown, Tex.) 20111201 |
| CDNA cloning and characterization of S6 kinase and its effect on yolk protein gene expression in the oriental fruit fly Bactrocera dorsalis (Hendel). | Archives of insect biochemistry and physiology 20111201 |
| Bifurcation stenting with a provisional T strategy: drug eluting stent type does matter. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20111201 |
| Rationale and design of the EXAMINATION trial: a randomised comparison between everolimus-eluting stents and cobalt-chromium bare-metal stents in ST-elevation myocardial infarction. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201 |
| Observations on enhanced port wine stain blanching induced by combined pulsed dye laser and rapamycin administration. | Lasers in surgery and medicine 20111201 |
| Anti-inflammatory and anti-fibrotic effects of sirolimus on bleomycin-induced pulmonary fibrosis in rats. | Clinical and investigative medicine. Medecine clinique et experimentale 20111201 |
| [Conversion from a calcineurin inhibitor to a sirolimus-based therapy after renal transplantation - An update of existing recommendations]. | Deutsche medizinische Wochenschrift (1946) 20111201 |
| Deoxyribose protects against rapamycin-induced cytotoxicity in colorectal cancer cells in vitro. | Nucleosides, nucleotides & nucleic acids 20111201 |
| [Antihormonal therapy in breast cancer and mTOR inhibitors]. | Bulletin du cancer 20111201 |
| Activation of mTOR signaling in medullary and aggressive papillary thyroid carcinomas. | Surgery 20111201 |
| Risk of target lesion failure in relationship to vessel angiographic geometry and stent conformability using the second generation of drug-eluting stents. | American heart journal 20111201 |
| Outcomes in patients undergoing multivessel percutaneous coronary intervention using sirolimus-eluting stents: a report from the e-SELECT registry. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111201 |
| Coronary pseudoaneurysm in a non-polymer drug-eluting stent: a rare entity. | Asian cardiovascular & thoracic annals 20111201 |
| Allosteric activation of kinases: design and application of RapR kinases. | Current protocols in cell biology 20111201 |
| Better actual 10-year renal transplant outcomes of 80% reduced cyclosporine exposure with sirolimus base therapy compared with full cyclosporine exposure without or with concomittant sirolimus treatment. | Transplantation proceedings 20111201 |
| Impact of the conversion of the immunosuppressive regimen from prograf to advagraf or to sirolimus in long-term stable liver transplant recipients: indications, safety, and outcome. | Transplantation proceedings 20111201 |
| Lipid profile changes during the first year after kidney transplantation: risk factors and influence of the immunosuppressive drug regimen. | Transplantation proceedings 20111201 |
| Oxidative stress indices in rats under immunosuppression. | Transplantation proceedings 20111201 |
| Stent area by intravascular ultrasound and outcomes in left main intervention with drug-eluting stents: small stents, more events. | Circulation. Cardiovascular interventions 20111201 |
| Head-to-head comparison of the neointimal response between metallic and bioresorbable everolimus-eluting scaffolds using optical coherence tomography. | JACC. Cardiovascular interventions 20111201 |
| Serial in vivo intravascular ultrasound-based echogenicity changes of everolimus-eluting bioresorbable vascular scaffold during the first 12 months after implantation insights from the ABSORB B trial. | JACC. Cardiovascular interventions 20111201 |
| A new era of prospective real-world safety evaluation primary report of XIENCE V USA (XIENCE V Everolimus Eluting Coronary Stent System condition-of-approval post-market study). | JACC. Cardiovascular interventions 20111201 |
| Mechanism of activation of AMPK and upregulation of OGG1 by rapamycin in cancer cells. | Oncotarget 20111201 |
| Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
| [What's new in dermatological therapy?]. | Annales de dermatologie et de venereologie 20111201 |
| Repetitive stent fractures with diffuse coronary artery microaneurysm formation--sirolimus eluting stent hypersensitivity? | Acta clinica Croatica 20111201 |
| Sirolimus and tacrolimus as immune prophylaxis compared to cyclosporine with or without methotrexate in patients undergoing allogeneic haematopoietic stem cell transplantation for non-malignant disorders. | European journal of haematology 20111201 |
| Combining an EGFR directed tyrosine kinase inhibitor with autophagy-inducing drugs: a beneficial strategy to combat non-small cell lung cancer. | Cancer letters 20111128 |
| Everolimus prevents endomyocardial remodeling after heart transplantation. | Transplantation 20111127 |
| Treatment of everolimus-resistant metastatic renal cell carcinoma with VEGF-targeted therapies. | British journal of cancer 20111122 |
| Small-molecule control of protein degradation using split adaptors. | ACS chemical biology 20111118 |
| Chemical tools for studying directed cell migration. | ACS chemical biology 20111118 |
| microRNA-101 is a potent inhibitor of autophagy. | The EMBO journal 20111116 |
| Phase 1/2 study of everolimus in advanced hepatocellular carcinoma. | Cancer 20111115 |
| Stent-related cardiac events beyond three years after implantation of the sirolimus-eluting stent (from the EVASTENT Patients). | The American journal of cardiology 20111115 |
| The role of skeletal muscle mTOR in the regulation of mechanical load-induced growth. | The Journal of physiology 20111115 |
| Nonobese diabetic natural killer cells: a barrier to allogeneic chimerism that can be reduced by rapamycin. | Transplantation 20111115 |
| Decreased lymphangiogenesis and lymph node metastasis by mTOR inhibition in head and neck cancer. | Cancer research 20111115 |
| Discovery and SAR exploration of a novel series of imidazo[4,5-b]pyrazin-2-ones as potent and selective mTOR kinase inhibitors. | Bioorganic & medicinal chemistry letters 20111115 |
| High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1. | Cell cycle (Georgetown, Tex.) 20111115 |
| Five-year outcomes of sirolimus-eluting versus paclitaxel-eluting stents: a propensity matched study: clinical evidence of late catch-up? | International journal of cardiology 20111103 |
| Turn motif phosphorylation negatively regulates activation loop phosphorylation in Akt. | Oncogene 20111103 |
| Nucleocytoplasmic localization of p70 S6K1, but not of its isoforms p85 and p31, is regulated by TSC2/mTOR. | Oncogene 20111103 |
| 'Sirolimus or paclitaxel drug eluting stent in left main disease: the winner is... '. | International journal of cardiology 20111103 |
| FRET detection of calmodulin binding to the cardiac RyR2 calcium release channel. | Biophysical journal 20111102 |
| Acute myocardial infarction related to very late sirolimus-eluting stent thrombosis 6 months after discontinuation of dual antiplatelet therapy. | Journal of cardiovascular medicine (Hagerstown, Md.) 20111101 |
| Effect of intravascular ultrasound-guided adjuvant high-pressure non-compliant balloon post-dilation after drug-eluting stent implantation. | Heart and vessels 20111101 |
| Utility of myocardial fractional flow reserve for prediction of restenosis following sirolimus-eluting stent implantation. | Heart and vessels 20111101 |
| Efficacy of paclitaxel-eluting stent implantation in hemodialysis patients. | Heart and vessels 20111101 |
| TGFβ- and bleomycin-induced extracellular matrix synthesis is mediated through Akt and mammalian target of rapamycin (mTOR). | Journal of cellular physiology 20111101 |
| [Association of post-transplant lymphoproliferative disease and visceral leishmaniasis after kidney transplantation]. | Nephrologie & therapeutique 20111101 |
| Low-dose sirolimus combined with angiotensin-converting enzyme inhibitor and statin stabilizes renal function and reduces glomerular proliferation in poor prognosis IgA nephropathy. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111101 |
| Influence of MRP2 on MPA pharmacokinetics in renal transplant recipients-results of the Pharmacogenomic Substudy within the Symphony Study. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111101 |
| Subconjunctival sirolimus in the treatment of diabetic macular edema. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20111101 |
| Autophagy induced by rapamycin and carbon-starvation have distinct proteome profiles in Aspergillus nidulans. | Biotechnology and bioengineering 20111101 |
| Chronic hypoxia-induced alterations of key enzymes of glucose oxidative metabolism in developing mouse liver are mTOR dependent. | Molecular and cellular biochemistry 20111101 |
| Differences in drug-eluting stents used in coronary artery disease. | The American journal of the medical sciences 20111101 |
| Activation of the phosphatidylinositol 3'-kinase/AKT pathway in neuroblastoma and its regulation by thioredoxin 1. | Human pathology 20111101 |
| mTOR signaling in polycystic kidney disease. | Trends in molecular medicine 20111101 |
| Identification of cancer stem cells in human gastrointestinal carcinoid and neuroendocrine tumors. | Gastroenterology 20111101 |
| Cytomegalovirus incidence between everolimus versus mycophenolate in de novo renal transplants: pooled analysis of three clinical trials. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101 |
| Hydrogel containing L-valine residues as a platform for cisplatin chemotherapy. | Colloids and surfaces. B, Biointerfaces 20111101 |
| The role of pre-conversion glomerular filtration rate in predicting long-term renal function after conversion to proliferation signal inhibitors in long-term heart transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20111101 |
| Global and threshold-free Transcriptional Regulatory Networks reconstruction through integrating ChIP-Chip and expression data. | Current protein & peptide science 20111101 |
| Multimodal biomarker investigation on efficacy and mechanism of action for the mammalian target of rapamycin inhibitor, temsirolimus, in a preclinical mammary carcinoma OncoMouse model: a translational medicine study in support for early clinical development. | The Journal of pharmacology and experimental therapeutics 20111101 |
| Comparison of angioscopic findings and three-year cardiac events between sirolimus-eluting stent and bare-metal stent in acute myocardial infarction. | The American journal of cardiology 20111101 |
| Monitoring of mycophenolic acid and kidney function during combined immunosuppressive therapy. | Clinical chemistry and laboratory medicine 20111101 |
| Hot-topic debate on hepatitis C virus: the type of immunosuppression matters. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20111101 |
| Outcome of sirolimus-eluting versus zotarolimus-eluting coronary stent implantation in patients with and without diabetes mellitus (a SORT OUT III Substudy). | The American journal of cardiology 20111101 |
| Rapamycin protects against dominant negative-HNF1A-induced apoptosis in INS-1 cells. | Apoptosis : an international journal on programmed cell death 20111101 |
| mTORC1 activation triggers the unfolded protein response in podocytes and leads to nephrotic syndrome. | Laboratory investigation; a journal of technical methods and pathology 20111101 |
| Elimination of norovirus in a chronic carrier under immunosuppression after heart transplantation--effect of everolimus. | Transplant international : official journal of the European Society for Organ Transplantation 20111101 |
| Rapamycin suppresses axon sprouting by somatostatin interneurons in a mouse model of temporal lobe epilepsy. | Epilepsia 20111101 |
| Calcineurin inhibitor minimization using sirolimus leads to improved renal function in pediatric heart transplant recipients. | Pediatric transplantation 20111101 |
| Calcineurin inhibitors in kidney transplantation: friend or foe? | Current opinion in nephrology and hypertension 20111101 |
| A phase I trial of liposomal doxorubicin, bevacizumab, and temsirolimus in patients with advanced gynecologic and breast malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111101 |
| Emerging roles for mammalian target of rapamycin inhibitors in the treatment of solid tumors and hematological malignancies. | Current opinion in oncology 20111101 |
| Systemic inhibition of the mammalian target of rapamycin (mTOR) pathway reduces neuropathic pain in mice. | Pain 20111101 |
| Immunosuppressant regimen based on sirolimus decreases aortic stiffness in renal transplant recipients in comparison to cyclosporine. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101 |
| Role of everolimus in pancreatic neuroendocrine tumors. | Expert review of anticancer therapy 20111101 |
| Sirolimus drug-eluting, hydrogel-impregnated polypropylene mesh reduces intra-abdominal adhesion formation in a mouse model. | Surgery 20111101 |
| Identifying inhibitors of epithelial-mesenchymal transition by connectivity map-based systems approach. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111101 |
| Limiting hepatitis C virus progression in liver transplant recipients using sirolimus-based immunosuppression. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101 |
| Sirolimus is coming of age. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20111101 |
| Clinical outcome of B2/C type isolated proximal LAD disease treated with drug-eluting stents. | Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20111101 |
| Inhibition of the mammalian target of rapamycin blocks epilepsy progression in NS-Pten conditional knockout mice. | Epilepsia 20111101 |
| Autophagy and the evasion of host defense: a new variation on the theme for Burkholderia cepacia? | Autophagy 20111101 |
| Autophagy stimulation by rapamycin suppresses lung inflammation and infection by Burkholderia cenocepacia in a model of cystic fibrosis. | Autophagy 20111101 |
| Sirolimus in pediatric renal transplantation. | Pediatric transplantation 20111101 |
| Sirolimus as renal and immunological rescue agent in pediatric liver transplant recipients. | Pediatric transplantation 20111101 |
| In situ quantitative imaging of cellular lipids using molecular sensors. | Nature chemistry 20111101 |
| The three year follow-up of the randomised 'all-comers' trial of a biodegradable polymer biolimus-eluting stent versus permanent polymer sirolimus-eluting stent (LEADERS). | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111101 |
| mTOR kinase inhibition results in oocyte loss characterized by empty follicles in human ovarian cortical strips cultured in vitro. | Fertility and sterility 20111101 |
| Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity. | Nature biotechnology 20111101 |
| [Second line AUO (Working Group Urological Oncology) study AB 35/09 on metastasized urothelial carcinoma. Phase II study with RAD001 in combination with paclitaxel for patients with metastasized urothelial carcinoma of the urinary bladder after failure of platinum-based chemotherapy (CRAD001)]. | Der Urologe. Ausg. A 20111101 |
| Successful treatment of a late presentation exercise-induced spontaneous left anterior descending artery dissection. | The Journal of invasive cardiology 20111101 |
| The Spanish experience with hand, forearm, and arm transplantation. | Hand clinics 20111101 |
| [Management of metastatic neuroendocrine tumors]. | Annales de pathologie 20111101 |
| Plant TOR signaling components. | Plant signaling & behavior 20111101 |
| Statistical analysis of noncommensurate multiple outcomes. | Circulation. Cardiovascular quality and outcomes 20111101 |
| Everolimus-induced loss of wound strength can be prevented by a short postoperative delay in its administration. | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20111101 |
| Long-term tissue coverage of a biodegradable polylactide polymer-coated biolimus-eluting stent: comparative sequential assessment with optical coherence tomography until complete resorption of the polymer. | American heart journal 20111101 |
| Mechanisms of very late stent thrombosis after drug-eluting stent implantation: findings from coronary angioscopy and optical coherence tomography. | JACC. Cardiovascular imaging 20111101 |
| Short-term immunossupressive treatment of the donor does not prevent ischemia-reperfusion kidney damage in the rat. | Transplantation proceedings 20111101 |
| De novo use of everolimus with elimination or minimization of cyclosporine in renal transplant recipients. | Transplantation proceedings 20111101 |
| Cost-effectiveness analysis of the early conversion of tacrolimus to mammalian target of rapamycin inhibitors in patients with renal transplantation. | Transplantation proceedings 20111101 |
| Impact of lesion length and vessel size on clinical outcomes after percutaneous coronary intervention with everolimus- versus paclitaxel-eluting stents pooled analysis from the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice) Randomized Trials. | JACC. Cardiovascular interventions 20111101 |
| Second-generation everolimus-eluting stents and the beat goes on? | JACC. Cardiovascular interventions 20111101 |
| Yeast-like chronological senescence in mammalian cells: phenomenon, mechanism and pharmacological suppression. | Aging 20111101 |
| The reverse, but coordinated, roles of Tor2 (TORC1) and Tor1 (TORC2) kinases for growth, cell cycle and separase-mediated mitosis in Schizosaccharomyces pombe. | Open biology 20111101 |
| Rapamycin passes the torch: a new generation of mTOR inhibitors. | Nature reviews. Drug discovery 20111031 |
| Unprotected left main stenting with a second-generation drug-eluting stent: one-year outcomes of the LEMAX Pilot study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20111030 |
| Rapamycin sensitive mTOR activation mediates nerve growth factor (NGF) induced cell migration and pro-survival effects against hydrogen peroxide in retinal pigment epithelial cells. | Biochemical and biophysical research communications 20111028 |
| Everolimus-eluting versus sirolimus-eluting stents in patients undergoing percutaneous coronary intervention: the EXCELLENT (Efficacy of Xience/Promus Versus Cypher to Reduce Late Loss After Stenting) randomized trial. | Journal of the American College of Cardiology 20111025 |
| Head-to-head randomized comparisons of limus-eluting coronary stents: pursuing excellence or flying too high? | Journal of the American College of Cardiology 20111025 |
| Autophagic degradation of farnesylated prelamin A as a therapeutic approach to lamin-linked progeria. | European journal of histochemistry : EJH 20111019 |
| Results of a prospective randomized trial of sirolimus conversion in kidney transplant recipients on early corticosteroid withdrawal. | Transplantation 20111015 |
| Switching from calcineurin inhibitors to Mammalian target of rapamycin inhibitors--finally caught the right wave? | Transplantation 20111015 |
| mTOR in podocyte function: is rapamycin good for diabetic nephropathy? | Cell cycle (Georgetown, Tex.) 20111015 |
| Impact of the everolimus-eluting stent on stent thrombosis: a meta-analysis of 13 randomized trials. | Journal of the American College of Cardiology 20111004 |
| Evaluation of the second generation of a bioresorbable everolimus-eluting vascular scaffold for the treatment of de novo coronary artery stenosis: 12-month clinical and imaging outcomes. | Journal of the American College of Cardiology 20111004 |
| The magic of disappearing stents. | Journal of the American College of Cardiology 20111004 |
| North Central Cancer Treatment Group Phase I trial N057K of everolimus (RAD001) and temozolomide in combination with radiation therapy in patients with newly diagnosed glioblastoma multiforme. | International journal of radiation oncology, biology, physics 20111001 |
| Assessment of the serial changes of vessel wall contents in atherosclerotic coronary lesion with bioresorbable everolimus-eluting vascular scaffolds using Shin's method: an IVUS study. | The international journal of cardiovascular imaging 20111001 |
| Weekly administration of temsirolimus for heavily pretreated patients with clear cell carcinoma of the ovary: a report of six cases. | International journal of clinical oncology 20111001 |
| In vivo therapeutic efficacy of intra-renal CD40 silencing in a model of humoral acute rejection. | Gene therapy 20111001 |
| Natural history, management and pharmacokinetics of everolimus-induced-oral ulcers: insights into compliance issues. | European journal of cancer (Oxford, England : 1990) 20111001 |
| Evaluation of the effects of the flavonoid apigenin on apoptotic pathway gene expression on the colon cancer cell line (HT29). | Journal of medicinal food 20111001 |
| Rapamycin and other longevity-promoting compounds enhance the generation of mouse induced pluripotent stem cells. | Aging cell 20111001 |
| Long-term response in advanced bladder cancer involving the use of temsirolimus and vinflunine after platin resistance. | Anti-cancer drugs 20111001 |
| Beclin 1-independent autophagy contributes to apoptosis in cortical neurons. | Autophagy 20111001 |
| Myxoma virus combined with rapamycin treatment enhances adoptive T cell therapy for murine melanoma brain tumors. | Cancer immunology, immunotherapy : CII 20111001 |
| Tissue coverage of a hydrophilic polymer-coated zotarolimus-eluting stent vs. a fluoropolymer-coated everolimus-eluting stent at 13-month follow-up: an optical coherence tomography substudy from the RESOLUTE All Comers trial. | European heart journal 20111001 |
| A topical combination of rapamycin and tacrolimus for the treatment of angiofibroma due to tuberous sclerosis complex (TSC): a pilot study of nine Japanese patients with TSC of different disease severity. | The British journal of dermatology 20111001 |
| Treatment of facial angiofibromas with topical application of oral rapamycin solution (1mgmL(-1) ) in two patients with tuberous sclerosis. | The British journal of dermatology 20111001 |
| Enhanced cellular uptake and in vivo pharmacokinetics of rapamycin-loaded cubic phase nanoparticles for cancer therapy. | Acta biomaterialia 20111001 |
| A ticking time bomb?: a case report of very late stent thrombosis more than 2 years after fracture of a Cypher stent. | Clinical research in cardiology : official journal of the German Cardiac Society 20111001 |
| Efficacy of re-challenging metastatic renal cell carcinoma with mTOR inhibitors. | Acta oncologica (Stockholm, Sweden) 20111001 |
| Phase II trial of the mTOR inhibitor, temsirolimus and evaluation of circulating tumor cells and tumor biomarkers in persistent and recurrent epithelial ovarian and primary peritoneal malignancies: a Gynecologic Oncology Group study. | Gynecologic oncology 20111001 |
| Leflunomide with low-dose everolimus for treatment of Kaposi's sarcoma in a renal allograft recipient. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20111001 |
| Sex differences in neointimal hyperplasia following endeavor zotarolimus-eluting stent implantation. | The American journal of cardiology 20111001 |
| Linking molecular feature space and disease terms for the immunosuppressive drug rapamycin. | Molecular bioSystems 20111001 |
| In vitro interaction of caspofungin and immunosuppressives against agents of mucormycosis. | The Journal of antimicrobial chemotherapy 20111001 |
| Serum levels after everolimus-stent implantation and paclitaxel-balloon angioplasty in an infant with recurrent pulmonary vein obstruction after repaired total anomalous pulmonary venous connection. | Pediatric cardiology 20111001 |
| Everolimus tablets for patients with subependymal giant cell astrocytoma. | Expert opinion on pharmacotherapy 20111001 |
| Antitumor activity of ridaforolimus and potential cell-cycle determinants of sensitivity in sarcoma and endometrial cancer models. | Molecular cancer therapeutics 20111001 |
| Inhibition of protein synthesis by TOR inactivation revealed a conserved regulatory mechanism of the BiP chaperone in Chlamydomonas. | Plant physiology 20111001 |
| De-novo calcineurin-inhibitor-free immunosuppression with sirolimus and mycophenolate mofetil after heart transplantation: 5-year results. | Current opinion in organ transplantation 20111001 |
| The TEA transcription factor Tec1 links TOR and MAPK pathways to coordinate yeast development. | Genetics 20111001 |
| Induction of autophagy with catalytic mTOR inhibitors reduces huntingtin aggregates in a neuronal cell model. | Journal of neurochemistry 20111001 |
| mTORC1 activity as a determinant of cancer risk--rationalizing the cancer-preventive effects of adiponectin, metformin, rapamycin, and low-protein vegan diets. | Medical hypotheses 20111001 |
| Role of biological targeted therapies in gastroenteropancreatic neuroendocrine tumours. | Endocrine 20111001 |
| Clinical presentation and management of mTOR inhibitor-associated stomatitis. | Oral oncology 20111001 |
| mTORC1- and mTORC2-interacting proteins keep their multifunctional partners focused. | IUBMB life 20111001 |
| Evaluation of zotarolimus-eluting metal stent in animal ureters. | Journal of endourology 20111001 |
| New target therapies for patients with neuroendocrine tumors of the pancreas. | Expert review of gastroenterology & hepatology 20111001 |
| Activation of protein kinase C-ζ in pancreatic β-cells in vivo improves glucose tolerance and induces β-cell expansion via mTOR activation. | Diabetes 20111001 |
| [The BASKET-PROVE study]. | Giornale italiano di cardiologia (2006) 20111001 |
| Vascular response to zotarolimus-coated balloons in injured superficial femoral arteries of the familial hypercholesterolemic Swine. | Circulation. Cardiovascular interventions 20111001 |
| Rapamycin induces differentiation of glioma stem/progenitor cells by activating autophagy. | Chinese journal of cancer 20111001 |
| ERas enhances resistance to CPT-11 in gastric cancer. | Anticancer research 20111001 |
| Sunitinib re-challenge in metastatic renal cell carcinoma treated sequentially with tyrosine kinase inhibitors and everolimus. | Anticancer research 20111001 |
| Alemtuzumab preconditioning allows steroid-calcineurin inhibitor-free regimen in live-donor kidney transplant. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20111001 |
| A meta-analysis of specifically designed randomized trials of sirolimus-eluting versus paclitaxel-eluting stents in diabetic patients with coronary artery disease. | American heart journal 20111001 |
| [Inflammation in tumor progression]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20111001 |
| Human peripheral blood CD8+ CD28- T cells of renal allograft recipients do not express FOXP3 protein. | Transplantation proceedings 20111001 |
| Long-term clinical and angiographic results of Sirolimus-Eluting Stent in Complex Coronary Chronic Total Occlusion Revascularization: the SECTOR registry. | Journal of interventional cardiology 20111001 |
| Erythematous patches and plaques on the chest with induration of the breasts. Metastatic papillary RCC in dermal lymphatics. | Archives of dermatology 20111001 |
| Bioresorbable polymeric vascular scaffolds: a cautionary tale. | Circulation. Cardiovascular interventions 20111001 |
| Vascular inflammation and repair: implications for re-endothelialization, restenosis, and stent thrombosis. | JACC. Cardiovascular interventions 20111001 |
| Assessing the temporal course of neointimal hyperplasia formation after different generations of drug-eluting stents. | JACC. Cardiovascular interventions 20111001 |
| Late vascular response following drug-eluting stent implantation. | JACC. Cardiovascular interventions 20111001 |
| Comparison of everolimus- and sirolimus-eluting stents in patients with long coronary artery lesions: a randomized LONG-DES-III (Percutaneous Treatment of LONG Native Coronary Lesions With Drug-Eluting Stent-III) Trial. | JACC. Cardiovascular interventions 20111001 |
| Comparison of everolimus- and paclitaxel-eluting stents in patients with acute and stable coronary syndromes: pooled results from the SPIRIT (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) and COMPARE (A Trial of Everolimus-Eluting Stents and Paclitaxel-Eluting Stents for Coronary Revascularization in Daily Practice) Trials. | JACC. Cardiovascular interventions 20111001 |
| Should everolimus-eluting stents be preferred in patients with acute and stable coronary syndromes? | JACC. Cardiovascular interventions 20111001 |
| Dual antiplatelet therapy duration and clinical outcomes following treatment with zotarolimus-eluting stents. | JACC. Cardiovascular interventions 20111001 |
| Will we ever know the optimal duration of dual antiplatelet therapy after drug-eluting stent implantation? | JACC. Cardiovascular interventions 20111001 |
| Three-dimensional reconstruction of the post-dilated ABSORB everolimus-eluting bioresorbable vascular scaffold in a true bifurcation lesion for flow restoration. | JACC. Cardiovascular interventions 20111001 |
| Two-year clinical outcomes of patients with long segments drug-eluting stents: comparison of sirolimus-eluting stent with paclitaxel-eluting stent. | Journal of Korean medical science 20111001 |
| Comparison of restenosis rate with sirolimus-eluting stent in STEMI patients with and without diabetes at 6-month angiographic follow-up. | Acta cardiologica 20111001 |
| Inactivation of mammalian target of rapamycin (mTOR) by rapamycin in a murine model of lipopolysaccharide-induced acute lung injury. | Chinese medical journal 20111001 |
| Real world clinical performance of the zotarolimus eluting coronary stent system in Chinese patients: a prospective, multicenter registry study. | Chinese medical journal 20111001 |
| Successful pregnancy complicated by persistent pneumothorax in a patient with lymphangioleiomyomatosis (LAM) on sirolimus. | Sarcoidosis, vasculitis, and diffuse lung diseases : official journal of WASOG 20111001 |
| [Effects of rapamycin on cholesterol homeostasis and secretory function of 3T3-L1 cells]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20111001 |
| Pediatric kidney transplantation followed by de novo therapy with everolimus, low-dose cyclosporine A, and steroid elimination: 3-year data. | Transplantation 20110927 |
| RNA polymerase II degradation in response to rapamycin is not mediated through ubiquitylation. | Biochemical and biophysical research communications 20110923 |
| Switching heterotrimeric G protein subunits with a chemical dimerizer. | Chemistry & biology 20110923 |
| Biodegradable polymer versus permanent polymer drug-eluting stents and everolimus- versus sirolimus-eluting stents in patients with coronary artery disease: 3-year outcomes from a randomized clinical trial. | Journal of the American College of Cardiology 20110920 |
| Drug-eluting versus bare-metal stents in saphenous vein graft lesions (ISAR-CABG): a randomised controlled superiority trial. | Lancet (London, England) 20110917 |
| Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling. | Antioxidants & redox signaling 20110915 |
| Rapamycin enhances the activity of oncolytic herpes simplex virus against tumor cells that are resistant to virus replication. | International journal of cancer 20110915 |
| A phase 1 study of everolimus and sorafenib for metastatic clear cell renal cell carcinoma. | Cancer 20110915 |
| Limitations in small intestinal neuroendocrine tumor therapy by mTor kinase inhibition reflect growth factor-mediated PI3K feedback loop activation via ERK1/2 and AKT. | Cancer 20110915 |
| An updated meta-analysis of randomized controlled trials of everolimus- versus paclitaxel-eluting stents. | International journal of cardiology 20110915 |
| Phase I trial of cixutumumab combined with temsirolimus in patients with advanced cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110915 |
| Using tandem mass spectrometry in targeted mode to identify activators of class IA PI3K in cancer. | Cancer research 20110915 |
| Combining EGFR and mTOR blockade for the treatment of epithelioid sarcoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110915 |
| Impact of de novo everolimus-based immunosuppression on incisional complications in heart transplantation. | Transplantation 20110915 |
| Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia. | Cell cycle (Georgetown, Tex.) 20110915 |
| Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors. | Cancer cell 20110913 |
| Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of a rapamycin analogue library. | ACS combinatorial science 20110912 |
| Salivary duct carcinoma: targeting the phosphatidylinositol 3-kinase pathway by blocking mammalian target of rapamycin with temsirolimus. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110910 |
| BCR-ABL suppresses autophagy through ATF5-mediated regulation of mTOR transcription. | Blood 20110908 |
| Small-molecule-based nanoassemblies as inducible nanoprobes for monitoring dynamic molecular interactions inside live cells. | Angewandte Chemie (International ed. in English) 20110905 |
| Acute cholecystitis in a patient with metastatic renal cell carcinoma treated with everolimus. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20110901 |
| Exaggerated inflammatory response following sirolimus-eluting stent fracture. | International journal of cardiology 20110901 |
| Rapamycin-induced posterior reversible encephalopathy in a kidney transplantation patient. | International urology and nephrology 20110901 |
| Optical coherence evaluation of everolimus-eluting stents 8 months after implantation. | Heart (British Cardiac Society) 20110901 |
| Combination of everolimus with calcineurin inhibitor medication resulted in post-transplant haemolytic uraemic syndrome in lung transplant recipients--a case series. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110901 |
| Combined inhibition of PI3K and mTOR exerts synergistic antiproliferative effect, but diminishes differentiative properties of rapamycin in acute myeloid leukemia cells. | Pathology oncology research : POR 20110901 |
| Lymphangioleiomyomatosis treatment with sirolimus. | Archivos de bronconeumologia 20110901 |
| Interaction of sirolimus and everolimus with hepatic and intestinal organic anion-transporting polypeptide transporters. | Xenobiotica; the fate of foreign compounds in biological systems 20110901 |
| Toxicity spectrum of inhibitors of mammalian target of rapamycin in organ transplantation: etiology, pathogenesis and treatment. | Expert opinion on drug safety 20110901 |
| [Metastatic renal cell cancer in Germany in 2010. Impact of different target therapies]. | Der Urologe. Ausg. A 20110901 |
| Sirolimus demonstrates activity in the primary therapy of acute graft-versus-host disease without systemic glucocorticoids. | Haematologica 20110901 |
| Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells. | Haematologica 20110901 |
| Intracellular angiotensin II activates rat myometrium. | American journal of physiology. Cell physiology 20110901 |
| Sirolimus-eluting stents vs. bare-metal stents for treatment of focal lesions in infrapopliteal arteries: a double-blind, multi-centre, randomized clinical trial. | European heart journal 20110901 |
| Assessment of the safety and biodistribution of a regulated AAV2 gene transfer vector after delivery to murine submandibular glands. | Toxicological sciences : an official journal of the Society of Toxicology 20110901 |
| New therapeutic options for metastatic malignant insulinomas. | Clinical endocrinology 20110901 |
| A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253. | Applied microbiology and biotechnology 20110901 |
| Paronychia and pyogenic granuloma induced by new anticancer mTOR inhibitors. | Acta dermato-venereologica 20110901 |
| Mesenchymal stem cells and carcinoma-associated fibroblasts sensitize breast cancer cells in 3D cultures to kinase inhibitors. | International journal of oncology 20110901 |
| Comparison of drug-eluting versus bare metal stents in cardiac allograft vasculopathy. | The American journal of cardiology 20110901 |
| Telmisartan reduces neointima volume and pulse wave velocity 8 months after zotarolimus-eluting stent implantation in hypertensive type 2 diabetic patients. | Heart (British Cardiac Society) 20110901 |
| The mTOR protein as a target in thyroid cancer. | Expert opinion on therapeutic targets 20110901 |
| Features of synergism between mesenchymal stem cells and immunosuppressive drugs in a murine heart transplantation model. | Transplant immunology 20110901 |
| Cystogenic potential of CD133+ progenitor cells of human polycystic kidneys. | The Journal of pathology 20110901 |
| Percutaneous coronary intervention in Takayasu's arteritis. | International journal of cardiology 20110901 |
| Influence of immunosuppressive agents on tryptophan degradation and neopterin production in human peripheral blood mononuclear cells. | Transplant immunology 20110901 |
| Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver. | Journal of lipid research 20110901 |
| Current management of lymphangioleiomyomatosis. | Current opinion in pulmonary medicine 20110901 |
| Sirolimus and growth. | Pediatric transplantation 20110901 |
| Identification of novel rapamycin derivatives as low-level impurities in active pharmaceutical ingredients. | The Journal of antibiotics 20110901 |
| Influence of low-dose aspirin (81 mg) on the incidence of definite stent thrombosis in patients receiving bare-metal and drug-eluting stents. | Clinical cardiology 20110901 |
| Azithromycin blocks autophagy and may predispose cystic fibrosis patients to mycobacterial infection. | The Journal of clinical investigation 20110901 |
| Randomized trial of immunosuppressive regimens in renal transplantation. | Journal of the American Society of Nephrology : JASN 20110901 |
| Managing refractory metastatic renal cell carcinoma: a RECORD spinning on a tilted AXIS. | Clinical genitourinary cancer 20110901 |
| Effects of immunosuppressive therapy after experimental small bowel transplantation in rats. | Transplant immunology 20110901 |
| Phase I trial of lenalidomide and CCI-779 in patients with relapsed multiple myeloma: evidence for lenalidomide-CCI-779 interaction via P-glycoprotein. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110901 |
| Editorial. | Current opinion in pulmonary medicine 20110901 |
| Sirolimus for acute pemphigus vulgaris: a case report and discussion of dualistic action providing for both immunosuppression and keratinocyte protection. | Journal of the American Academy of Dermatology 20110901 |
| Neuroendocrine regulation of autophagy by leptin. | Cell cycle (Georgetown, Tex.) 20110901 |
| The mTOR inhibitor RAD001 sensitizes tumor cells to the cytotoxic effect of carboplatin in breast cancer in vitro. | Anticancer research 20110901 |
| Involvement of Akt and mTOR in chemotherapeutic- and hormonal-based drug resistance and response to radiation in breast cancer cells. | Cell cycle (Georgetown, Tex.) 20110901 |
| Sirolimus-based immunosuppression for treatment of cutaneous warts in kidney transplant recipients. | Iranian journal of kidney diseases 20110901 |
| Graft-versus-host disease therapy: something else beyond glucocorticoids? | Haematologica 20110901 |
| Renal carcinoma with (6;11)(p21;q12) translocation: report of an adult case. | Pathology international 20110901 |
| Linear growth in pediatric renal transplant recipients receiving sirolimus. | Pediatric transplantation 20110901 |
| Persistent dyspnea in a 59-year-old woman receiving immunosuppressants. | Chest 20110901 |
| Long-term experience with everolimus in kidney transplantation in the United States. | Transplantation proceedings 20110901 |
| A retrospective 12-month study of conversion to everolimus in lung transplant recipients. | Transplantation proceedings 20110901 |
| Sirolimus-induced pneumonitis complicated by pentamidine-induced phospholipidosis in a renal transplant recipient: a case report. | Transplantation proceedings 20110901 |
| Everolimus and sunitinib: from mouse models to treatment of pancreatic neuroendocrine tumors. | Future oncology (London, England) 20110901 |
| IVUS and OCT: either or survivor …. | JACC. Cardiovascular imaging 20110901 |
| Hepatocellular carcinoma and liver transplantation: clinical perspective on molecular targeted strategies. | Medical molecular morphology 20110901 |
| Three-year outcome of sirolimus-eluting stent implantation in coronary bifurcation lesions: the provisional side branch stenting approach versus the elective two-stent approach. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901 |
| Implantation of the biodegradable polymer biolimus-eluting stent in patients with high SYNTAX score is associated with decreased cardiac mortality compared to a permanent polymer sirolimus-eluting stent: two year follow-up results from the 'all-comers' LEADERS trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901 |
| Bifurcation Optimisation Stent System (BiOSS Lim) with sirolimus elution: results from porcine coronary artery model. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110901 |
| Dramatic improvement of facial angiofibromas in tuberous sclerosis with topical rapamycin: optimizing a treatment protocol. | Archives of dermatology 20110901 |
| Impact of intravascular ultrasound imaging on early and late clinical outcomes following percutaneous coronary intervention with drug-eluting stents. | JACC. Cardiovascular interventions 20110901 |
| Sirolimus-eluting coronary stents in octogenarians: a 1-year analysis of the worldwide e-SELECT Registry. | JACC. Cardiovascular interventions 20110901 |
| Serial analysis of the malapposed and uncovered struts of the new generation of everolimus-eluting bioresorbable scaffold with optical coherence tomography. | JACC. Cardiovascular interventions 20110901 |
| Total aorto-ostial chronic occlusion of the right coronary artery successfully recanalized via retrograde approach. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110901 |
| [Synergistic cytotoxic effects of rapamycin and idarubicin on human acute T-cell lymphoblastic leukemia Jurkat cells]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20110901 |
| The successful management of diffuse lymphangiomatosis using sirolimus: a case report. | The Laryngoscope 20110901 |
| [Ryanodine downregulates the expression of p-eNOS (Thr495) and improves the functions of rapamycin treated endothelial outgrowth cells]. | Zhonghua xin xue guan bing za zhi 20110901 |
| [Basic efficiently of drug eluting stent 2011]. | Nihon rinsho. Japanese journal of clinical medicine 20110901 |
| [Sirolimis-eluting stent (SES)]. | Nihon rinsho. Japanese journal of clinical medicine 20110901 |
| [Zotarolimus-eluting stent]. | Nihon rinsho. Japanese journal of clinical medicine 20110901 |
| [Everolimus-eluting stent]. | Nihon rinsho. Japanese journal of clinical medicine 20110901 |
| [Biolimus eluting stent]. | Nihon rinsho. Japanese journal of clinical medicine 20110901 |
| [Effect of RAD001 or plus LBH589 on the proliferation, apoptosis and drug resistance in chemoresistant acute myeloid leukemic cells]. | Zhonghua yi xue za zhi 20110830 |
| Conversion of long-term kidney transplant recipients from calcineurin inhibitor therapy to everolimus: a randomized, multicenter, 24-month study. | Transplantation 20110827 |
| Role of S6K1 in regulation of SREBP1c expression in the liver. | Biochemical and biophysical research communications 20110826 |
| Localized ultrasound enhances delivery of rapamycin from microbubbles to prevent smooth muscle proliferation. | Journal of controlled release : official journal of the Controlled Release Society 20110825 |
| Safety and efficacy of everolimus, a mTOR inhibitor, as single agent in a phase 1/2 study in patients with myelofibrosis. | Blood 20110825 |
| Rapamycin and IL-2 reduce lethal acute graft-versus-host disease associated with increased expansion of donor type CD4+CD25+Foxp3+ regulatory T cells. | Blood 20110825 |
| Randomized comparison of everolimus-eluting stent versus sirolimus-eluting stent implantation for de novo coronary artery disease in patients with diabetes mellitus (ESSENCE-DIABETES): results from the ESSENCE-DIABETES trial. | Circulation 20110823 |
| Differential clinical responses to everolimus-eluting and Paclitaxel-eluting coronary stents in patients with and without diabetes mellitus. | Circulation 20110823 |
| Is diabetes the achilles' heel of limus-eluting stents? | Circulation 20110823 |
| Phase II study of temsirolimus in women with recurrent or metastatic endometrial cancer: a trial of the NCIC Clinical Trials Group. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110820 |
| Sirolimus- vs. paclitaxel-eluting stents for the treatment of unprotected left main coronary artery stenosis: complete 2-year follow-up of a two-center registry. | International journal of cardiology 20110818 |
| Regulation of TFEB and V-ATPases by mTORC1. | The EMBO journal 20110817 |
| Inhibition of mammalian target of rapamycin signaling by everolimus induces senescence in adult T-cell leukemia/lymphoma and apoptosis in peripheral T-cell lymphomas. | International journal of cancer 20110815 |
| Everolimus-eluting versus paclitaxel-eluting stents for treatment of bare metal stent restenosis. | The American journal of cardiology 20110815 |
| Therapeutic efficacy of polyclonal tregs does not require rapamycin in a low-dose irradiation bone marrow transplantation model. | Transplantation 20110815 |
| Lower malignancy rates in renal allograft recipients converted to sirolimus-based, calcineurin inhibitor-free immunotherapy: 24-month results from the CONVERT trial. | Transplantation 20110815 |
| Antagonistic control of muscle cell size by AMPK and mTORC1. | Cell cycle (Georgetown, Tex.) 20110815 |
| Everolimus and long-term outcomes in renal transplantation: seeking an optimal strategy for immunosuppression. | Transplantation 20110815 |
| Everolimus and long-term outcomes in renal transplantation. | Transplantation 20110815 |
| Phase I/II study of trastuzumab in combination with everolimus (RAD001) in patients with HER2-overexpressing metastatic breast cancer who progressed on trastuzumab-based therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110810 |
| Polymer-free sirolimus- and probucol-eluting versus new generation zotarolimus-eluting stents in coronary artery disease: the Intracoronary Stenting and Angiographic Results: Test Efficacy of Sirolimus- and Probucol-Eluting versus Zotarolimus-eluting Stents (ISAR-TEST 5) trial. | Circulation 20110802 |
| Human herpes virus type 8-associated Kaposi sarcoma in a pediatric liver transplant recipient. | Pediatric transplantation 20110801 |
| The mammalian target of rapamycin inhibitor everolimus (RAD001) in early breast cancer: results of a pre-operative study. | Breast cancer research and treatment 20110801 |
| Are we missing the mTOR target in breast cancer? | Breast cancer research and treatment 20110801 |
| Potent antifibrotic activity of mTOR inhibitors sirolimus and everolimus but not of cyclosporine A and tacrolimus in experimental liver fibrosis. | Journal of hepatology 20110801 |
| A phase 2 study of temsirolimus (CCI-779) in patients with soft tissue sarcomas: a study of the Mayo phase 2 consortium (P2C). | Cancer 20110801 |
| The management of subependymal giant cell tumors in tuberous sclerosis: a clinician's perspective. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110801 |
| Oral rapamycin in the treatment of patients with hamartoma syndromes and PTEN mutation. | Pediatric blood & cancer 20110801 |
| Conversion to everolimus in maintenance liver transplant patients: a multicenter, retrospective analysis. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20110801 |
| Angiographic outcomes with biodegradable polymer and permanent polymer drug-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110801 |
| The influence of co-solvents on the stability and bioavailability of rapamycin formulated in self-microemulsifying drug delivery systems. | Drug development and industrial pharmacy 20110801 |
| Low stent thrombosis risk with the XIENCE V® Everolimus-Eluting Coronary Stent: evidence from randomized and single-arm clinical trials. | Journal of interventional cardiology 20110801 |
| Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways. | British journal of pharmacology 20110801 |
| FKBPs in chromatin modification and cancer. | Current opinion in pharmacology 20110801 |
| Successful treatment of systemic de novo sarcoidosis with cyclosporine discontinuation and provision of rapamune after liver transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20110801 |
| A pulse rapamycin therapy for infantile spasms and associated cognitive decline. | Neurobiology of disease 20110801 |
| Hepatocyte growth factor-induced c-Src-phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway inhibits dendritic cell activation by blocking IκB kinase activity. | The international journal of biochemistry & cell biology 20110801 |
| Subsets of human CD4(+) regulatory T cells express the peripheral homing receptor CXCR3. | European journal of immunology 20110801 |
| Focus. | Journal of hepatology 20110801 |
| Induction of tolerance to factor VIII by transient co-administration with rapamycin. | Journal of thrombosis and haemostasis : JTH 20110801 |
| Sustained targeting of Bcr-Abl + leukemia cells by synergistic action of dual drug loaded nanoparticles and its implication for leukemia therapy. | Biomaterials 20110801 |
| Inhibition of the mTOR/p70S6K pathway is not involved in the insulin-sensitizing effect of AMPK on cardiac glucose uptake. | American journal of physiology. Heart and circulatory physiology 20110801 |
| A 3-in-1 polymeric micelle nanocontainer for poorly water-soluble drugs. | Molecular pharmaceutics 20110801 |
| Modulation of morphogenesis in Candida albicans by various small molecules. | Eukaryotic cell 20110801 |
| Cholesterol esters as growth regulators of lymphocytic leukaemia cells. | Cell proliferation 20110801 |
| Tilt balance towards regulation: evolving new strategy for treatment of hemophilia inhibitors. | Journal of thrombosis and haemostasis : JTH 20110801 |
| First clinical trial of nitinol self-expanding everolimus-eluting stent implantation for peripheral arterial occlusive disease. | Journal of vascular surgery 20110801 |
| The ORION study: comparison of two sirolimus-based regimens versus tacrolimus and mycophenolate mofetil in renal allograft recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801 |
| How to use mTOR inhibitors? The search goes on. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801 |
| Rapamycin-induced hypophosphatemia and insulin resistance are associated with mTORC2 activation and Klotho expression. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801 |
| Preclinical characterization of OSI-027, a potent and selective inhibitor of mTORC1 and mTORC2: distinct from rapamycin. | Molecular cancer therapeutics 20110801 |
| Direct activation of mTOR in B lymphocytes confers impairment in B-cell maturation andloss of marginal zone B cells. | European journal of immunology 20110801 |
| Combinatorial effects of lapatinib and rapamycin in triple-negative breast cancer cells. | Molecular cancer therapeutics 20110801 |
| The use of everolimus in pediatric liver transplant recipients: first experience in a single center. | Pediatric transplantation 20110801 |
| Sirolimus-eluting stent implantation for ostial left anterior descending coronary artery lesions: three-year outcome from the j-Cypher Registry. | Circulation. Cardiovascular interventions 20110801 |
| The mTOR/AKT inhibitor temsirolimus prevents deep infiltrating endometriosis in mice. | The American journal of pathology 20110801 |
| Evaluation of the Abbott ARCHITECT i2000 sirolimus assay and comparison with the Abbott IMx sirolimus assay and an established liquid chromatography-tandem mass spectrometry method. | Therapeutic drug monitoring 20110801 |
| Evaluation of performance of new, isotopically labeled internal standard ([13c2d4]RAD001) for everolimus using a novel high-performance liquid chromatography tandem mass spectrometry method. | Therapeutic drug monitoring 20110801 |
| TORCing up the importance of calcium signaling. | Journal of the American Society of Nephrology : JASN 20110801 |
| Skin cancer in solid organ transplant recipients: advances in therapy and management: part I. Epidemiology of skin cancer in solid organ transplant recipients. | Journal of the American Academy of Dermatology 20110801 |
| mTor plays an important role in odontoblast differentiation. | Journal of endodontics 20110801 |
| mTOR inhibitors in advanced renal cell carcinoma. | Hematology/oncology clinics of North America 20110801 |
| Quality of life and targeted treatment for metastatic renal cell carcinoma. | The oncologist 20110801 |
| How can we miss you, if you will never leave? Biodegradable stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110801 |
| Everolimus-eluting versus sirolimus-eluting stents: a meta-analysis of randomized trials. | Circulation. Cardiovascular interventions 20110801 |
| A phase II trial of bevacizumab plus everolimus for patients with refractory metastatic colorectal cancer. | The oncologist 20110801 |
| Efficacy and safety of early cyclosporine conversion to sirolimus with continued MMF-four-year results of the Postconcept study. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110801 |
| Impact of sirolimus-eluting stent fracture on 4-year clinical outcomes. | Circulation. Cardiovascular interventions 20110801 |
| Everolimus vs. rapamycin for treating diabetic nephropathy in diabetic mouse model. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110801 |
| Effects of rapamycin on expression of Bcl-2 and Bax in human lens epithelial cells and cell cycle in rats. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110801 |
| Comparison of six-year clinical outcome of sirolimus- and paclitaxel-eluting stents to bare-metal stents in patients with ST-segment elevation myocardial infarction: an analysis of the RESEARCH (rapamycin-eluting stent evaluated at Rotterdam cardiology hospital) and T-SEARCH (taxus stent evaluated at Rotterdam cardiology hospital) registries. | The Journal of invasive cardiology 20110801 |
| Long-term benefit using DES in STEMI patients. | The Journal of invasive cardiology 20110801 |
| Rapamycin as an antiaging therapeutic?: targeting mammalian target of rapamycin to treat Hutchinson-Gilford progeria and neurodegenerative diseases. | Rejuvenation research 20110801 |
| Meeting report: American Aging Association 40th Annual Meeting, Raleigh, North Carolina, June 3-6, 2011. | Rejuvenation research 20110801 |
| 2-year clinical follow-up from the randomized comparison of biolimus-eluting stents with biodegradable polymer and sirolimus-eluting stents with durable polymer in routine clinical practice. | JACC. Cardiovascular interventions 20110801 |
| Everolimus: an mTOR inhibitor for the treatment of tuberous sclerosis. | Expert review of anticancer therapy 20110801 |
| [Rapamycin for myeloid blast crisis in refractory chronic myeloid leukemia with imatinib-resistance]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110801 |
| A shining light in the darkness for the treatment of pancreatic neuroendocrine tumors. | Cancer discovery 20110801 |
| Use of remote film loading methodology to entrap sirolimus into liposomes: preparation, characterization and in vivo efficacy for treatment of restenosis. | International journal of pharmaceutics 20110729 |
| Controlled poly(l-lactide-co-trimethylene carbonate) delivery system of cyclosporine A and rapamycine--the effect of copolymer chain microstructure on drug release rate. | International journal of pharmaceutics 20110729 |
| Everolimus for cardiac allograft vasculopathy--every patient, at any time? | Transplantation 20110727 |
| Racial variation in the development of posttransplant lymphoproliferative disorders after renal transplantation. | Transplantation 20110727 |
| Effect of everolimus introduction on cardiac allograft vasculopathy--results of a randomized, multicenter trial. | Transplantation 20110727 |
| [Adverse effects of new oncologic therapies]. | Praxis 20110727 |
| PIK3CA mutation, but not PTEN loss of function, determines the sensitivity of breast cancer cells to mTOR inhibitory drugs. | Oncogene 20110721 |
| Efficacy and safety of sirolimus in lymphangioleiomyomatosis. | The New England journal of medicine 20110721 |
| Efficacy and safety of sirolimus in lymphangioleiomyomatosis. | The New England journal of medicine 20110721 |
| Phase I study of temsirolimus in pediatric patients with recurrent/refractory solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110720 |
| Fighting neurodegeneration with rapamycin: mechanistic insights. | Nature reviews. Neuroscience 20110720 |
| The role of autophagy emerging in postinfarction cardiac remodelling. | Cardiovascular research 20110715 |
| Transplant-associated thrombotic microangiopathy in pediatric patients treated with sirolimus and tacrolimus. | Pediatric blood & cancer 20110715 |
| Effect of pioglitazone on endothelial dysfunction after sirolimus-eluting stent implantation. | The American journal of cardiology 20110715 |
| mTORC2 protein complex-mediated Akt (Protein Kinase B) Serine 473 Phosphorylation is not required for Akt1 activity in human platelets [corrected]. | The Journal of biological chemistry 20110715 |
| CCI-779 inhibits cell-cycle G2-M progression and invasion of castration-resistant prostate cancer via attenuation of UBE2C transcription and mRNA stability. | Cancer research 20110715 |
| Inhibiting the mTOR pathway synergistically enhances cytotoxicity in ovarian cancer cells induced by etoposide through upregulation of c-Jun. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110715 |
| Insights into ALK-driven cancers revealed through development of novel ALK tyrosine kinase inhibitors. | Cancer research 20110715 |
| Everolimus- versus first generation drug-eluting stents: the never-ending story of searching for a winner in the 'limus family'. | International journal of cardiology 20110715 |
| The power of chemotherapeutic engineering: arresting cell cycle and suppressing senescence to protect from mitotic inhibitors. | Cell cycle (Georgetown, Tex.) 20110715 |
| Stents versus CABG for left main coronary artery disease. | The New England journal of medicine 20110714 |
| Stents versus CABG for left main coronary artery disease. | The New England journal of medicine 20110714 |
| 6-month clinical outcomes following implantation of the bioresorbable everolimus-eluting vascular scaffold in vessels smaller or larger than 2.5 mm. | Journal of the American College of Cardiology 20110712 |
| L-threonine regulates G1/S phase transition of mouse embryonic stem cells via PI3K/Akt, MAPKs, and mTORC pathways. | The Journal of biological chemistry 20110708 |
| Rapamycin (sirolimus) protects against hypoxic damage in primary heart cultures via Na+/Ca2+ exchanger activation. | Life sciences 20110704 |
| Comparison of chronic-stage histopathological findings among 3 coronary stents implanted in the same patient. | International journal of cardiology 20110701 |
| Rapamycin synergizes cisplatin sensitivity in basal-like breast cancer cells through up-regulation of p73. | Breast cancer research and treatment 20110701 |
| Temporal changes of coronary artery plaque located behind the struts of the everolimus eluting bioresorbable vascular scaffold. | The international journal of cardiovascular imaging 20110701 |
| Down-regulation of the ubiquitin-proteasome proteolysis system by amino acids and insulin involves the adenosine monophosphate-activated protein kinase and mammalian target of rapamycin pathways in rat hepatocytes. | Amino acids 20110701 |
| Long-term (≥2 years) follow-up optical coherence tomographic study after sirolimus- and paclitaxel-eluting stent implantation: comparison to 9-month follow-up results. | The international journal of cardiovascular imaging 20110701 |
| The mTOR pathway affects proliferation and chemosensitivity of urothelial carcinoma cells and is upregulated in a subset of human bladder cancers. | BJU international 20110701 |
| mTORC1 activation in childhood ependymoma and response to sirolimus. | Journal of neuro-oncology 20110701 |
| Serial angiographic and intravascular ultrasound evaluation to interrogate the presence of late 'catch-up' phenomenon after Cypher® sirolimus-eluting stent implantation. | The international journal of cardiovascular imaging 20110701 |
| Long-term outcome after sirolimus-eluting stents versus bare metal stents in patients with diabetes mellitus: a patient-level meta-analysis of randomized trials. | Clinical research in cardiology : official journal of the German Cardiac Society 20110701 |
| Twelve-month clinical outcomes of everolimus-eluting stent as compared to paclitaxel- and sirolimus-eluting stent in patients undergoing percutaneous coronary interventions. A meta-analysis of randomized clinical trials. | International journal of cardiology 20110701 |
| Percutaneous intervention of a thrombotic-occluded saphenous vein graft successfully treated using the undersized stent approach to prevent distal embolization. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701 |
| An investigator-driven study of everolimus in surgical lung biopsy confirmed idiopathic pulmonary fibrosis. | Respirology (Carlton, Vic.) 20110701 |
| Comparison of in vivo acute stent recoil between the bioresorbable everolimus-eluting coronary scaffolds (revision 1.0 and 1.1) and the metallic everolimus-eluting stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701 |
| Dual mTORC2/mTORC1 targeting results in potent suppressive effects on acute myeloid leukemia (AML) progenitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
| Primum non nocere: safety in clinical trials for IPF. | Respirology (Carlton, Vic.) 20110701 |
| A phase I study of sirolimus and bevacizumab in patients with advanced malignancies. | European journal of cancer (Oxford, England : 1990) 20110701 |
| Curcumin disrupts uterine leiomyosarcoma cells through AKT-mTOR pathway inhibition. | Gynecologic oncology 20110701 |
| Rapamycin inhibits formation of urethral stricture in rabbits. | The Journal of pharmacology and experimental therapeutics 20110701 |
| The serine/threonine kinase Pim-2 is a novel anti-apoptotic mediator in myeloma cells. | Leukemia 20110701 |
| Rapamycin-sensitive signals control TCR/CD28-driven Ifng, Il4 and Foxp3 transcription and promoter region methylation. | European journal of immunology 20110701 |
| Responses to liposomal Doxorubicin, bevacizumab, and temsirolimus in metaplastic carcinoma of the breast: biologic rationale and implications for stem-cell research in breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110701 |
| Relapse of aplastic anemia responsive to sirolimus combined with cyclosporine. | Pediatric blood & cancer 20110701 |
| Meta-analysis of everolimus-eluting stent as compared to sirolimus-eluting stent in patients undergoing percutaneous coronary interventions: an update. | International journal of cardiology 20110701 |
| Starvation and rapamycin differentially regulate host cell lysosome exocytosis and invasion by Trypanosoma cruzi metacyclic forms. | Cellular microbiology 20110701 |
| mTORC1 inhibition increases neurotensin secretion and gene expression through activation of the MEK/ERK/c-Jun pathway in the human endocrine cell line BON. | American journal of physiology. Cell physiology 20110701 |
| Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non-small-cell lung cancer cells. | Cancer science 20110701 |
| Phase I trial of capecitabine plus everolimus (RAD001) in patients with previously treated metastatic gastric cancer. | Cancer chemotherapy and pharmacology 20110701 |
| CD4(+)CD25(high)CD127(low) regulatory T cells in patients with stable angina and their dynamics after intracoronary sirolimus-eluting stent implantation. | Human immunology 20110701 |
| Continuing response to subsequent treatment lines with tyrosine kinase inhibitors in an adolescent with metastatic renal cell carcinoma. | Journal of pediatric hematology/oncology 20110701 |
| Rheb/mTOR activation and regulation in cancer: novel treatment strategies beyond rapamycin. | Current drug targets 20110701 |
| Role of ROS in the protective effect of silibinin on sodium nitroprusside-induced apoptosis in rat pheochromocytoma PC12 cells. | Free radical research 20110701 |
| High-throughput LC-MS/MS method for monitoring sirolimus and everolimus in the routine clinical laboratory. | Clinical chemistry and laboratory medicine 20110701 |
| Rapamycin partially mimics the anticancer effects of calorie restriction in a murine model of pancreatic cancer. | Cancer prevention research (Philadelphia, Pa.) 20110701 |
| Rapamycin-conditioned, alloantigen-pulsed myeloid dendritic cells present donor MHC class I/peptide via the semi-direct pathway and inhibit survival of antigen-specific CD8(+) T cells in vitro and in vivo. | Transplant immunology 20110701 |
| An adjusted indirect comparison of everolimus and sorafenib therapy in sunitinib-refractory metastatic renal cell carcinoma patients using repeated matched samples. | Expert opinion on pharmacotherapy 20110701 |
| Involvement of 4E-BP phosphorylation in embryonic development of the silkworm, Bombyx mori. | Journal of insect physiology 20110701 |
| Combination of PI3K/mTOR inhibitors: antitumor activity and molecular correlates. | Cancer research 20110701 |
| Restenosis after implantation of sirolimus-eluting stent begins suddenly, shows short term progression, and stops suddenly. | Journal of cardiology 20110701 |
| The activity of trabectedin as a single agent or in combination with everolimus for clear cell carcinoma of the ovary. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110701 |
| S6 kinase 1 is required for rapamycin-sensitive liver proliferation after mouse hepatectomy. | The Journal of clinical investigation 20110701 |
| mTOR and the differentiation of mesenchymal stem cells. | Acta biochimica et biophysica Sinica 20110701 |
| Temsirolimus and bevacizumab, or sunitinib, or interferon alfa and bevacizumab for patients with advanced renal cell carcinoma (TORAVA): a randomised phase 2 trial. | The Lancet. Oncology 20110701 |
| Combination therapy in metastatic renal cell carcinoma. | The Lancet. Oncology 20110701 |
| Structural identification of SAR-943 metabolites generated by human liver microsomes in vitro using mass spectrometry in combination with analysis of fragmentation patterns. | Journal of mass spectrometry : JMS 20110701 |
| Modulation of autophagy influences development and apoptosis in mouse embryos developing in vitro. | Molecular reproduction and development 20110701 |
| Testing the strength of biodegradable stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110701 |
| Cost-effectiveness of drug-eluting stents versus bare metal stents in clinical practice. | Circulation. Cardiovascular quality and outcomes 20110701 |
| [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. | Aktuelle Urologie 20110701 |
| [The influence of rapamycin on BTLA expression of human peripheral blood T lymphocytes]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20110701 |
| Monitoring ketamine treatment response in a depressed patient via peripheral mammalian target of rapamycin activation. | The American journal of psychiatry 20110701 |
| Successful stent implantation guided by intravascular ultrasound and a Doppler guidewire without contrast injection in a patient with allergy to iodinated contrast media. | The Journal of invasive cardiology 20110701 |
| Transient coronary aneurysm formation after Nevo™ stent implantation versus persistent coronary aneurysm after Cypher Select™ stent implantation. | The Journal of invasive cardiology 20110701 |
| Local delivery of rapamycin: a toxicity and efficacy study in an experimental malignant glioma model in rats. | Neuro-oncology 20110701 |
| Should stent selection in diabetic patients be considered as a special case? | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701 |
| Clinical and angiographic outcomes of elderly patients treated with everolimus-eluting versus paclitaxel-eluting stents: three-year results from the SPIRIT III randomised trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701 |
| Late lumen loss and intima hyperplasia after sirolimus-eluting and zotarolimus-eluting stent implantation in diabetic patients: the diabetes and drug-eluting stent (DiabeDES III) angiography and intravascular ultrasound trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110701 |
| Involvement of Akt-1 and mTOR in sensitivity of breast cancer to targeted therapy. | Oncotarget 20110701 |
| Ridaforolimus: a promising drug in the treatment of soft-tissue sarcoma and other malignancies. | Future oncology (London, England) 20110701 |
| Rapamycin is a potent inhibitor of skin tumor promotion by 12-O-tetradecanoylphorbol-13-acetate. | Cancer prevention research (Philadelphia, Pa.) 20110701 |
| Changes in reference vessel diameter in ST-segment elevation myocardial infarction after primary percutaneous coronary intervention: implications for appropriate stent sizing. | American heart journal 20110701 |
| Progeria, rapamycin and normal aging: recent breakthrough. | Aging 20110701 |
| Impact of drug release kinetics on vascular response to different zotarolimus-eluting stents implanted in patients with long coronary stenoses: the LongOCT study (Optical Coherence Tomography in Long Lesions). | JACC. Cardiovascular interventions 20110701 |
| Linking drug-eluting stent kinetics and clinical outcomes: insights from optical coherence tomography. | JACC. Cardiovascular interventions 20110701 |
| Development of a biodegradable sirolimus-eluting stent coated by ultrasonic atomizing spray. | Journal of nanoscience and nanotechnology 20110701 |
| An increase in basal BDNF provokes hyperactivation of the Akt-mammalian target of rapamycin pathway and deregulation of local dendritic translation in a mouse model of Down's syndrome. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110629 |
| Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells. | Science translational medicine 20110629 |
| 2-year follow-up of a randomized controlled trial of everolimus- and paclitaxel-eluting stents for coronary revascularization in daily practice. COMPARE (Comparison of the everolimus eluting XIENCE-V stent with the paclitaxel eluting TAXUS LIBERTÉ stent in all-comers: a randomized open label trial). | Journal of the American College of Cardiology 20110628 |
| Randomized comparison of everolimus- and paclitaxel-eluting stents. 2-year follow-up from the SPIRIT (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System) IV trial. | Journal of the American College of Cardiology 20110628 |
| Second-generation drug-eluting stents. Moving the field forward. | Journal of the American College of Cardiology 20110628 |
| Tacrolimus and sirolimus induce reproductive abnormalities in female rats. | Transplantation 20110627 |
| Five-year outcomes of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: are they equally good (or bad)? | Circulation 20110621 |
| Five-year clinical and angiographic outcomes of a randomized comparison of sirolimus-eluting and paclitaxel-eluting stents: results of the Sirolimus-Eluting Versus Paclitaxel-Eluting Stents for Coronary Revascularization LATE trial. | Circulation 20110621 |
| Summaries for patients. Sirolimus therapy in patients with lymphangioleiomyomatosis. | Annals of internal medicine 20110621 |
| Changes in lung function and chylous effusions in patients with lymphangioleiomyomatosis treated with sirolimus. | Annals of internal medicine 20110621 |
| Tuberous sclerosis complex and lymphangioleiomyomatosis: miles to go, promises to keep. | Annals of internal medicine 20110621 |
| Mammalian target of rapamycin: a central node of complex signaling cascades. | International journal of clinical and experimental pathology 20110620 |
| A proof of concept phase II non-inferiority criterion. | Statistics in medicine 20110615 |
| Outcomes after unrestricted use of everolimus-eluting stent compared to paclitaxel- and sirolimus-eluting stents. | The American journal of cardiology 20110615 |
| Sirolimus therapy for angiomyolipoma in tuberous sclerosis and sporadic lymphangioleiomyomatosis: a phase 2 trial. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110615 |
| Comparison of everolimus-eluting stent with paclitaxel-eluting stent in long chronic total occlusions. | The American journal of cardiology 20110615 |
| mTOR kinase inhibitor AZD8055 enhances the immunotherapeutic activity of an agonist CD40 antibody in cancer treatment. | Cancer research 20110615 |
| Persistent long-term synaptic plasticity requires activation of a new signaling pathway by additional stimuli. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110615 |
| Intestinal absorption and intestinal lymphatic transport of sirolimus from self-microemulsifying drug delivery systems assessed using the single-pass intestinal perfusion (SPIP) technique and a chylomicron flow blocking approach: linear correlation with oral bioavailabilities in rats. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110614 |
| [Role of rapamycin in cholangiocytes regeneration after liver transplantation]. | Zhonghua yi xue za zhi 20110614 |
| Cell signaling. New mTOR targets Grb attention. | Science (New York, N.Y.) 20110610 |
| The mTOR-regulated phosphoproteome reveals a mechanism of mTORC1-mediated inhibition of growth factor signaling. | Science (New York, N.Y.) 20110610 |
| Phosphoproteomic analysis identifies Grb10 as an mTORC1 substrate that negatively regulates insulin signaling. | Science (New York, N.Y.) 20110610 |
| Regulation of yeast chronological life span by TORC1 via adaptive mitochondrial ROS signaling. | Cell metabolism 20110608 |
| Late asymptomatic sirolimus-eluting stent fracture in a female with systemic lupus erythematosus. | International journal of cardiology 20110602 |
| Leucine promotes leptin receptor expression in mouse C2C12 myotubes through the mTOR pathway. | Molecular biology reports 20110601 |
| Thrombotic thrombocytopenic purpura associated with everolimus use in a renal transplant patient. | International urology and nephrology 20110601 |
| The selective VEGFR1-3 inhibitor axitinib (AG-013736) shows antitumor activity in human neuroblastoma xenografts. | International journal of cancer 20110601 |
| Retinoic acid induces autophagosome maturation through redistribution of the cation-independent mannose-6-phosphate receptor. | Antioxidants & redox signaling 20110601 |
| Four-year clinical follow-up of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT II trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110601 |
| Extended follow-up safety and effectiveness of the Endeavor zotarolimus-eluting stent in real-world clinical practice: two-year follow-up from the E-Five Registry. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110601 |
| Prophylaxis with sirolimus and tacrolimus ± antithymocyte globulin reduces the risk of acute graft-versus-host disease without an overall survival benefit following allogeneic stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110601 |
| Donor pre-treatment with everolimus or cyclosporine does not reduce ischaemia-reperfusion injury in a rat kidney transplant model. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110601 |
| Decrease in transient receptor potential melastatin 6 mRNA stability caused by rapamycin in renal tubular epithelial cells. | Biochimica et biophysica acta 20110601 |
| Expansion of CD4(+)CD25 (+) regulatory T cells from cord blood CD4(+) cells using the common γ-chain cytokines (IL-2 and IL-15) and rapamycin. | Annals of hematology 20110601 |
| Clinical and molecular insights into tuberous sclerosis complex renal disease. | Pediatric nephrology (Berlin, Germany) 20110601 |
| Endothelium-dependent coronary vasomotor response and neointimal coverage of zotarolimus-eluting stents 3 months after implantation. | Heart (British Cardiac Society) 20110601 |
| Poly(ethylene glycol)-block-poly(2-methyl-2-benzoxycarbonyl-propylene carbonate) micelles for rapamycin delivery: in vitro characterization and biodistribution. | Journal of pharmaceutical sciences 20110601 |
| Recent developments in drug-eluting stents. | Journal of molecular medicine (Berlin, Germany) 20110601 |
| Temsirolimus in advanced leiomyosarcomas: patterns of response and correlation with the activation of the mammalian target of rapamycin pathway. | Anti-cancer drugs 20110601 |
| Targeting glycolysis in leukemia: a novel inhibitor 3-BrOP in combination with rapamycin. | Leukemia research 20110601 |
| PDGF-induced vascular smooth muscle cell proliferation is associated with dysregulation of insulin receptor substrates. | American journal of physiology. Cell physiology 20110601 |
| Five-year experience using sirolimus-based, calcineurin inhibitor-free immunosuppression in pediatric renal transplantation. | Pediatric transplantation 20110601 |
| Growth of kidney-transplanted pediatric patients treated with sirolimus. | Pediatric nephrology (Berlin, Germany) 20110601 |
| Efficacy of ganitumab (AMG 479), alone and in combination with rapamycin, in Ewing's and osteogenic sarcoma models. | The Journal of pharmacology and experimental therapeutics 20110601 |
| Complete induction of autophagy is essential for cardioprotection in sepsis. | Annals of surgery 20110601 |
| Dramatic tumor response to everolimus for malignant epithelioid angiomyolipoma. | Japanese journal of clinical oncology 20110601 |
| mTOR complex 2 activation by reconstituted high-density lipoprotein prevents senescence in circulating angiogenic cells. | Arteriosclerosis, thrombosis, and vascular biology 20110601 |
| Autophagy protects against aminochrome-induced cell death in substantia nigra-derived cell line. | Toxicological sciences : an official journal of the Society of Toxicology 20110601 |
| mTOR inhibition, a potential novel approach for bronchial carcinoids. | Endocrine-related cancer 20110601 |
| The real world experience of the everolimus-eluting coronary stent system: audit of everolimus-eluting coronary stents. | Journal of interventional cardiology 20110601 |
| Effects of rapamycin and TOR on aging and memory: implications for Alzheimer's disease. | Journal of neurochemistry 20110601 |
| [Collecting duct renal cell carcinoma]. | Actas urologicas espanolas 20110601 |
| Impact of combined HDAC and mTOR inhibition on adhesion, migration and invasion of prostate cancer cells. | Clinical & experimental metastasis 20110601 |
| Adiponectin induces vascular smooth muscle cell differentiation via repression of mammalian target of rapamycin complex 1 and FoxO4. | Arteriosclerosis, thrombosis, and vascular biology 20110601 |
| The PTEN/PI3K/Akt pathway regulates stem-like cells in primary esophageal carcinoma cells. | Cancer biology & therapy 20110601 |
| Mammalian target of rapamycin expression in poorly differentiated endocrine carcinoma: clinical and therapeutic future challenges. | Targeted oncology 20110601 |
| Acid β-glucosidase mutants linked to Gaucher disease, Parkinson disease, and Lewy body dementia alter α-synuclein processing. | Annals of neurology 20110601 |
| Treatment of metastatic renal cell carcinoma and renal pelvic cancer. | Clinical and experimental nephrology 20110601 |
| Management of adverse events associated with the use of everolimus in patients with advanced renal cell carcinoma. | European journal of cancer (Oxford, England : 1990) 20110601 |
| Impaired autophagy: a link between neurodegenerative diseases and progressive myoclonus epilepsies. | Trends in molecular medicine 20110601 |
| Everolimus induces rapid plasma glucose normalization in insulinoma patients by effects on tumor as well as normal tissues. | The oncologist 20110601 |
| Ridaforolimus (AP23573; MK-8669), a potent mTOR inhibitor, has broad antitumor activity and can be optimally administered using intermittent dosing regimens. | Molecular cancer therapeutics 20110601 |
| Everolimus augments the effects of sorafenib in a syngeneic orthotopic model of hepatocellular carcinoma. | Molecular cancer therapeutics 20110601 |
| An intein-cassette integration approach used for the generation of a split TEV protease activated by conditional protein splicing. | Molecular bioSystems 20110601 |
| Chemotherapy-related bilateral dermatitis associated with eccrine squamous syringometaplasia: reappraisal of epidemiological, clinical, and pathological features. | Journal of the American Academy of Dermatology 20110601 |
| Common toxicities of mammalian target of rapamycin inhibitors. | Targeted oncology 20110601 |
| Bone healing after secondary surgery on hand allografts under sirolimus-based maintenance immunosuppression. | Annals of plastic surgery 20110601 |
| Predictive biomarkers for the activity of mammalian target of rapamycin (mTOR) inhibitors. | Targeted oncology 20110601 |
| Long-term outcomes of sirolimus-eluting stents vs. paclitaxel-eluting stents in unprotected left main coronary artery bifurcation lesions. | Clinical cardiology 20110601 |
| Clinical activity of mammalian target of rapamycin inhibitors in solid tumors. | Targeted oncology 20110601 |
| Targeting phosphatidylinositol 3 kinase (PI3K)-Akt beyond rapalogs. | Targeted oncology 20110601 |
| Generation and large-scale expansion of human inducible regulatory T cells that suppress graft-versus-host disease. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110601 |
| mTOR phosphorylates IMP2 to promote IGF2 mRNA translation by internal ribosomal entry. | Genes & development 20110601 |
| Impact of polymer formulations on neointimal proliferation after zotarolimus-eluting stent with different polymers: insights from the RESOLUTE trial. | Circulation. Cardiovascular interventions 20110601 |
| The role of sirolimus in the prevention of cutaneous squamous cell carcinoma in organ transplant recipients. | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20110601 |
| Role of mTOR in podocyte function and diabetic nephropathy in humans and mice. | The Journal of clinical investigation 20110601 |
| mTORC1 activation in podocytes is a critical step in the development of diabetic nephropathy in mice. | The Journal of clinical investigation 20110601 |
| The targeted podocyte. | The Journal of clinical investigation 20110601 |
| Hypoxia-induced ROS signaling is required for LOX up-regulation in endothelial cells. | Frontiers in bioscience (Elite edition) 20110601 |
| Sirolimus: not so sparing in the Spare-the-Nephron trial. | Kidney international 20110601 |
| Temsirolimus in relapsed and/or refractory mantle cell lymphoma†: profile report. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20110601 |
| Posttransplant distal limb syndrome. | The Journal of orthopaedic and sports physical therapy 20110601 |
| No role for early IGF-1 signalling in stimulating acute 'muscle building' responses. | The Journal of physiology 20110601 |
| The isomerase Rrd1 mediates rapid loss of the Sgs1 helicase in response to rapamycin. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20110601 |
| The possibility of delayed arterial healing 5 years after implantation of sirolimus-eluting stents: serial observations by coronary angioscopy. | American heart journal 20110601 |
| Aberrant CD8+ T-cell responses and memory differentiation upon viral infection of an ataxia-telangiectasia mouse model driven by hyper-activated Akt and mTORC1 signaling. | The American journal of pathology 20110601 |
| Are we ready to move away from nature?: the rapamycin story. | Targeted oncology 20110601 |
| Enhanced efficacy of sirolimus-eluting bioabsorbable magnesium alloy stents in the prevention of restenosis. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110601 |
| Commentary: Deliver the drug and disappear: is the bioabsorbable magnesium stent growing up or still shrinking? | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110601 |
| Sirolimus therapy predisposes to new-onset diabetes mellitus after renal transplantation: a long-term analysis of various treatment regimens. | Transplantation proceedings 20110601 |
| Vascular endothelial function of sirolimus maintenance regimen in renal transplant recipients. | Transplantation proceedings 20110601 |
| Laparoscopic incisional hernia repair after solid-organ transplantation. | Transplantation proceedings 20110601 |
| Everolimus plus dosage reduction of cyclosporine in cardiac transplant recipients with chronic kidney disease: a two-year follow-up study. | Transplantation proceedings 20110601 |
| Calcineurin inhibitor-free immunosuppression using everolimus (Certican) after heart transplantation: 2 years' follow-up from the University Hospital Münster. | Transplantation proceedings 20110601 |
| Efficacy and safety of sirolimus and everolimus in heart transplant patients: a retrospective analysis. | Transplantation proceedings 20110601 |
| Long-term maintenance therapy for post-cardiac transplant monoclonal lymphoproliferative disorder: caveat mammalian target of rapamycin. | Transplantation proceedings 20110601 |
| Local application of rapamycin inhibits vein graft restenosis in rabbits. | Transplantation proceedings 20110601 |
| Comparison of titanium-nitride-oxide-coated stents with zotarolimus-eluting stents for coronary revascularization a randomized controlled trial. | JACC. Cardiovascular interventions 20110601 |
| Paclitaxel-eluting balloons for sirolimus-eluting stent restenosis. | JACC. Cardiovascular interventions 20110601 |
| In-stent restenosis after revascularization of myocardium with drug-eluting stents is accompanied by elevated level of blood plasma eosinophil cationic protein. | Canadian journal of physiology and pharmacology 20110601 |
| Incidence, risk factors, and clinical sequelae of angiographic peri-stent contrast staining after sirolimus-eluting stent implantation. | Circulation 20110531 |
| The impact of patient and lesion complexity on clinical and angiographic outcomes after revascularization with zotarolimus- and everolimus-eluting stents: a substudy of the RESOLUTE All Comers Trial (a randomized comparison of a zotarolimus-eluting stent with an everolimus-eluting stent for percutaneous coronary intervention). | Journal of the American College of Cardiology 20110531 |
| Hormonally active vitamin D3 (1alpha,25-dihydroxycholecalciferol) triggers autophagy in human macrophages that inhibits HIV-1 infection. | The Journal of biological chemistry 20110527 |
| Prospective study of everolimus with calcineurin inhibitor-free immunosuppression in maintenance heart transplant patients: results at 2 years. | Transplantation 20110527 |
| Everolimus and minimization of cyclosporine in renal transplantation: 24-month follow-up of the EVEREST study. | Transplantation 20110527 |
| Genetic and clinical risk factors of new-onset diabetes after transplantation in Hispanic kidney transplant recipients. | Transplantation 20110527 |
| Long-term comparison of everolimus-eluting and sirolimus-eluting stents for coronary revascularization. | Journal of the American College of Cardiology 20110524 |
| Akt/mammalian target of rapamycin signaling pathway regulates neurite outgrowth in cerebellar granule neurons stimulated by methylcobalamin. | Neuroscience letters 20110520 |
| The long and winding road to rational treatment of cancer associated with LKB1/AMPK/TSC/mTORC1 signaling. | Oncogene 20110519 |
| Combination of direct and adjusted indirect comparisons of sirolimus- versus paclitaxel-eluting stents for ST-segment elevation myocardial infarction. | International journal of cardiology 20110519 |
| [Effects of sirolimus upon endothelial thrombotic function of human umbilical vein endothelial cells]. | Zhonghua yi xue za zhi 20110517 |
| Targeting the JNK signaling pathway potentiates the antiproliferative efficacy of rapamycin in LS174T colon cancer cells. | The Journal of surgical research 20110515 |
| Sirolimus and proteinuria in renal transplant patients: evidence for a dose-dependent effect on slit diaphragm-associated proteins. | Transplantation 20110515 |
| Successful pregnancy in a living-related kidney transplant recipient who received sirolimus throughout the whole gestation. | Transplantation 20110515 |
| Advances in pancreatic neuroendocrine tumor treatment. | The New England journal of medicine 20110512 |
| Everolimus- and temsirolimus-associated enteritis: report of three cases. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110510 |
| Phosphomimetic substitution of heterogeneous nuclear ribonucleoprotein A1 at serine 199 abolishes AKT-dependent internal ribosome entry site-transacting factor (ITAF) function via effects on strand annealing and results in mammalian target of rapamycin complex 1 (mTORC1) inhibitor sensitivity. | The Journal of biological chemistry 20110506 |
| Randomized trial of stents versus bypass surgery for left main coronary artery disease. | The New England journal of medicine 20110505 |
| Everolimus interferes with the inflammatory phase of healing in experimental colonic anastomoses. | The Journal of surgical research 20110501 |
| Biodegradable sirolimus-loaded poly(lactide) nanoparticles as drug delivery system for the prevention of in-stent restenosis in coronary stent application. | Journal of biomaterials applications 20110501 |
| Rapamycin suppresses ROS-dependent apoptosis caused by selenomethionine in A549 lung carcinoma cells. | Cancer chemotherapy and pharmacology 20110501 |
| Therapy of sclerodermatous chronic graft-versus-host disease with mammalian target of rapamycin inhibitors. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501 |
| Double umbilical cord blood transplantation with reduced intensity conditioning and sirolimus-based GVHD prophylaxis. | Bone marrow transplantation 20110501 |
| Strategies to prevent EBV reactivation and posttransplant lymphoproliferative disorders (PTLD) after allogeneic stem cell transplantation in high-risk patients. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20110501 |
| Evaluation of sphingolipid metabolism in renal cortex of rats with streptozotocin-induced diabetes and the effects of rapamycin. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110501 |
| The 5352 A allele of the pro-inflammatory caspase-1 gene predicts late-acquired stent malapposition in STEMI patients treated with sirolimus stents. | Heart and vessels 20110501 |
| Adoptive transfer of CD4+CD25+ regulatory cells combined with low-dose sirolimus and anti-thymocyte globulin delays acute rejection of renal allografts in Cynomolgus monkeys. | International immunopharmacology 20110501 |
| Generation of human regulatory T cells de novo with suppressive function prevent xenogeneic graft versus host disease. | International immunopharmacology 20110501 |
| Somatostatin analogues for treatment of polycystic liver disease. | Current opinion in gastroenterology 20110501 |
| Predictors of long-term renal function after conversion to proliferation signal inhibitors in long-term heart transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110501 |
| GSK3β inactivation in podocytes results in decreased phosphorylation of p70S6K accompanied by cytoskeletal rearrangements and inhibited motility. | American journal of physiology. Renal physiology 20110501 |
| Differential effects of rapamycin on rods and cones during light-induced stress in albino mice. | Investigative ophthalmology & visual science 20110501 |
| Costimulatory blockade with mTor inhibition abrogates effector T-cell responses allowing regulatory T-cell survival in renal transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20110501 |
| Visfatin exerts angiogenic effects on human umbilical vein endothelial cells through the mTOR signaling pathway. | Biochimica et biophysica acta 20110501 |
| Targeted inhibition of mTORC1 and mTORC2 by active-site mTOR inhibitors has cytotoxic effects in T-cell acute lymphoblastic leukemia. | Leukemia 20110501 |
| Lack of compensatory pAKT activation and eIF4E phosphorylation of lymphoma cells towards mTOR inhibitor, RAD001. | European journal of cancer (Oxford, England : 1990) 20110501 |
| Rapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardium. | American journal of physiology. Heart and circulatory physiology 20110501 |
| Rapamycin inhibits hydrogen peroxide-induced loss of vascular contractility. | American journal of physiology. Heart and circulatory physiology 20110501 |
| Temsirolimus inhibits malignant pleural mesothelioma growth in vitro and in vivo: synergism with chemotherapy. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110501 |
| AMPK and substrate availability regulate creatine transport in cultured cardiomyocytes. | American journal of physiology. Endocrinology and metabolism 20110501 |
| The antagonist of the JAK-1/STAT-1 signaling pathway improves the severity of cerulein-stimulated pancreatic injury via inhibition of NF-κB activity. | International journal of molecular medicine 20110501 |
| Five-year clinical follow-up after sirolimus-eluting stent implantation for the treatment of coronary in-stent restenosis. | Coronary artery disease 20110501 |
| Effects of mTOR inhibitor everolimus (RAD001) on bladder cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110501 |
| The mTOR-targeting drug temsirolimus enhances the growth-inhibiting effects of the cetuximab-bevacizumab-irradiation combination on head and neck cancer xenografts. | Oral oncology 20110501 |
| The potential benefits and risks of the use of dual antiplatelet therapy beyond 6 months following sirolimus-eluting stent implantation for low-risk patients. | Journal of cardiology 20110501 |
| Drug-related pneumonitis in patients with advanced renal cell carcinoma treated with temsirolimus. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110501 |
| Patient-reported outcomes in a phase iii study of everolimus versus placebo in patients with metastatic carcinoma of the kidney that has progressed on vascular endothelial growth factor receptor tyrosine kinase inhibitor therapy. | The oncologist 20110501 |
| Secreted factors from brain endothelial cells maintain glioblastoma stem-like cell expansion through the mTOR pathway. | EMBO reports 20110501 |
| Regression of a cardiac rhabdomyoma in a patient receiving everolimus. | Pediatrics 20110501 |
| Clinical outcomes by geographic region for patients implanted with the zotarolimus-eluting stent. | Arquivos brasileiros de cardiologia 20110501 |
| Everolimus for the treatment of advanced renal cell carcinoma. | Expert opinion on pharmacotherapy 20110501 |
| The cutaneous effects of post-transplant immunosuppression with cyclosporine in Muir-Torre syndrome. | Journal of the American Academy of Dermatology 20110501 |
| Efficacy and comparative effectiveness of sirolimus as an anticancer drug. | The Laryngoscope 20110501 |
| CD40-specific costimulation blockade enhances neonatal porcine islet survival in nonhuman primates. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110501 |
| Ex vivo transfer of adenovirus-mediated CTLA4Ig gene combined with a short course of rapamycin therapy prolongs free flap allograft survival. | Plastic and reconstructive surgery 20110501 |
| Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts. | Annals of vascular surgery 20110501 |
| Predictors of death or myocardial infarction, ischaemic-driven revascularisation, and major adverse cardiovascular events following everolimus-eluting or paclitaxel-eluting stent deployment: pooled analysis from the SPIRIT II, III, IV and COMPARE trials. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501 |
| PLATINUM QCA: a prospective, multicentre study assessing clinical, angiographic, and intravascular ultrasound outcomes with the novel platinum chromium thin-strut PROMUS Element everolimus-eluting stent in de novo coronary stenoses. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501 |
| Impact of drug-eluting stent type on periprocedural myocardial necrosis. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501 |
| Rationale and design of the clinical evaluation of the Resolute Zotarolimus-Eluting Coronary Stent System in the treatment of de novo lesions in native coronary arteries (the RESOLUTE US clinical trial). | American heart journal 20110501 |
| Late-term clinical outcomes with zotarolimus- and sirolimus-eluting stents. 5-year follow-up of the ENDEAVOR III (A Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions). | JACC. Cardiovascular interventions 20110501 |
| My stent is better than your stent...Or is it? | JACC. Cardiovascular interventions 20110501 |
| Usefulness of rotational atherectomy in preventing polymer damage of everolimus-eluting stent in calcified coronary artery. | JACC. Cardiovascular interventions 20110501 |
| Experimental study of the anticancer effect of gemcitabine combined with sirolimus on chemically induced urothelial lesions. | Anticancer research 20110501 |
| Once-a-day administration of everolimus is safe in de novo renal transplant recipients: 1-year results of a pilot study. | Transplantation proceedings 20110501 |
| University of Modena experience in HIV-positive patients undergoing liver transplantation. | Transplantation proceedings 20110501 |
| Causes of sirolimus discontinuation in 97 liver transplant recipients. | Transplantation proceedings 20110501 |
| Incisional hernia after simultaneous pancreas kidney tranplantation: a single-center experience from Budapest. | Transplantation proceedings 20110501 |
| Coactivation of receptor tyrosine kinases in malignant mesothelioma as a rationale for combination targeted therapy. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110501 |
| Optical coherence tomography (OCT) in PCI for in-stent restenosis (ISR): rationale and design of the SEDUCE (Safety and Efficacy of a Drug elUting balloon in Coronary artery rEstenosis) study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501 |
| Local drug delivery - the early Berlin experience: single drug administration versus sustained release. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501 |
| Paclitaxel and sirolimus differentially affect growth and motility of endothelial progenitor cells and coronary artery smooth muscle cells. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501 |
| A prospective randomised study using optical coherence tomography to assess endothelial coverage and neointimal proliferation at 6-months after implantation of a coronary everolimus-eluting stent compared with a bare metal stent postdilated with a paclitaxel-eluting balloon (OCTOPUS Trial): rationale, design and methods. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110501 |
| Patient organizations and research on rare diseases. | The New England journal of medicine 20110428 |
| Efficacy and safety of sirolimus in lymphangioleiomyomatosis. | The New England journal of medicine 20110428 |
| Clinical evaluation of the Resolute zotarolimus-eluting coronary stent system in the treatment of de novo lesions in native coronary arteries: the RESOLUTE US clinical trial. | Journal of the American College of Cardiology 20110426 |
| Isolation and structure of homotemsirolimuses A, B, and C. | Journal of natural products 20110425 |
| [Novelties in the treatment for advanced renal-cell cancer]. | Orvosi hetilap 20110424 |
| The inhibition of MAPK potentiates the anti-angiogenic efficacy of mTOR inhibitors. | Biochemical and biophysical research communications 20110422 |
| Inhibition of mTOR blocks the anti-inflammatory effects of glucocorticoids in myeloid immune cells. | Blood 20110421 |
| Leishmania repression of host translation through mTOR cleavage is required for parasite survival and infection. | Cell host & microbe 20110421 |
| Response of lymphangioleiomyomatosis to a mammalian target of rapamycin inhibitor (temsirolimus) -based treatment. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110420 |
| Recent studies show promise for treating rare pancreatic tumors. | Journal of the National Cancer Institute 20110420 |
| A prospective, randomized evaluation of a novel everolimus-eluting coronary stent: the PLATINUM (a Prospective, Randomized, Multicenter Trial to Assess an Everolimus-Eluting Coronary Stent System [PROMUS Element] for the Treatment of Up to Two de Novo Coronary Artery Lesions) trial. | Journal of the American College of Cardiology 20110419 |
| Glutamate N-methyl-D-aspartate receptor antagonists rapidly reverse behavioral and synaptic deficits caused by chronic stress exposure. | Biological psychiatry 20110415 |
| Comparison of three-year clinical outcomes after sirolimus-eluting stent implantation among insulin-treated diabetic, non-insulin-treated diabetic, and non-diabetic patients from j-Cypher registry. | The American journal of cardiology 20110415 |
| Rapamycin impairs proliferation of transplanted islet β cells. | Transplantation 20110415 |
| Generation of adaptive regulatory T cells by alloantigen is required for some but not all transplant tolerance protocols. | Transplantation 20110415 |
| Ex vivo rapamycin treatment of human cord blood CD34+ cells enhances their engraftment of NSG mice. | Blood cells, molecules & diseases 20110415 |
| Th17 cells in alemtuzumab-treated patients: the effect of long-term maintenance immunosuppressive therapy. | Transplantation 20110415 |
| Identification and elimination of ion suppression in the quantitative analysis of sirolimus in human blood by LC/ESI-MS/MS. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415 |
| An accurate quantitative LC/ESI-MS/MS method for sirolimus in human whole blood. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110415 |
| Clinical outcome, angiographic outcome, and coronary endothelial function after drug-eluting stent implantation. | Journal of the American College of Cardiology 20110412 |
| Unrestricted randomised use of two new generation drug-eluting coronary stents: 2-year patient-related versus stent-related outcomes from the RESOLUTE All Comers trial. | Lancet (London, England) 20110409 |
| Long-term safety and efficacy of drug-eluting stents. | Lancet (London, England) 20110409 |
| WIPI1 coordinates melanogenic gene transcription and melanosome formation via TORC1 inhibition. | The Journal of biological chemistry 20110408 |
| A phase II study of everolimus in combination with imatinib for previously treated advanced renal carcinoma. | Investigational new drugs 20110401 |
| Melanoma: from darkness to promise. | American journal of clinical oncology 20110401 |
| Complete fracture and migration of a coronary sirolimus-eluting stent. | Journal of cardiovascular medicine (Hagerstown, Md.) 20110401 |
| An investigation of reversal of imatinib resistance in the Bcr-Abl positive imatinib-resistant cell line K562r by dasatinib, nilotinib, rapamycin and bortezomib. | International journal of laboratory hematology 20110401 |
| The pharmacokinetics of Biolimus A9 after elution from the BioMatrix II stent in patients with coronary artery disease: the Stealth PK Study. | European journal of clinical pharmacology 20110401 |
| A high-throughput fluorescence chemical denaturation assay as a general screen for protein-ligand binding. | Analytical biochemistry 20110401 |
| Bfl-1/A1 acts as a negative regulator of autophagy in mycobacteria infected macrophages. | The international journal of biochemistry & cell biology 20110401 |
| Development and characterization of clinically relevant tumor models from patients with renal cell carcinoma. | European urology 20110401 |
| Hot topics in aging research: protein translation and TOR signaling, 2010. | Aging cell 20110401 |
| Autophagy regulates myeloid cell differentiation by p62/SQSTM1-mediated degradation of PML-RARα oncoprotein. | Autophagy 20110401 |
| Mycophenolate mofetil-based immunosuppression with sirolimus in renal transplantation: a randomized, controlled Spare-the-Nephron trial. | Kidney international 20110401 |
| Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis. | Autophagy 20110401 |
| Comparison of haemodialysis patients and non-haemodialysis patients with respect to clinical characteristics and 3-year clinical outcomes after sirolimus-eluting stent implantation: insights from the Japan multi-centre post-marketing surveillance registry. | European heart journal 20110401 |
| Late catch-up phenomenon associated with stent fracture after sirolimus-eluting stent implantation: incidence and outcome. | Journal of interventional cardiology 20110401 |
| Smooth muscle protein-22-mediated deletion of Tsc1 results in cardiac hypertrophy that is mTORC1-mediated and reversed by rapamycin. | Human molecular genetics 20110401 |
| Volumetric analysis of MRI data monitoring the treatment of polycystic kidney disease in a mouse model. | Magma (New York, N.Y.) 20110401 |
| Zymosan suppresses leukotriene C₄ synthase activity in differentiating monocytes: antagonism by aspirin and protein kinase inhibitors. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110401 |
| Oleate-mediated activation of phospholipase D and mammalian target of rapamycin (mTOR) regulates proliferation and rapamycin sensitivity of hepatocarcinoma cells. | Diabetologia 20110401 |
| Evaluation of QMS everolimus assay using Hitachi 917 Analyzer: comparison with liquid chromatography/mass spectrometry. | Therapeutic drug monitoring 20110401 |
| Targeting of active mTOR inhibits primary leukemia T cells and synergizes with cytotoxic drugs and signaling inhibitors. | Experimental hematology 20110401 |
| Secretion of three enzymes for fatty acid synthesis into mouse milk in association with fat globules, and rapid decrease of the secreted enzymes by treatment with rapamycin. | Archives of biochemistry and biophysics 20110401 |
| Rapamycin reverses splenomegaly and inhibits tumor development in a transgenic model of Epstein-Barr virus-related Burkitt's lymphoma. | Molecular cancer therapeutics 20110401 |
| The Akt-specific inhibitor MK2206 selectively inhibits thyroid cancer cells harboring mutations that can activate the PI3K/Akt pathway. | The Journal of clinical endocrinology and metabolism 20110401 |
| Microstructure and drug-release studies of sirolimus-containing poly(lactide-co-glycolide) films. | Journal of biomedical materials research. Part B, Applied biomaterials 20110401 |
| Inhibition by rapamycin of the lipoteichoic acid-induced granulocyte-colony stimulating factor expression in mouse macrophages. | Archives of biochemistry and biophysics 20110401 |
| The novel Raf inhibitor Raf265 decreases Bcl-2 levels and confers TRAIL-sensitivity to neuroendocrine tumour cells. | Endocrine-related cancer 20110401 |
| The identification of raptor as a substrate for p44/42 MAPK. | Endocrinology 20110401 |
| Targeting the mTOR kinase domain: the second generation of mTOR inhibitors. | Drug discovery today 20110401 |
| Imidazo[1,5-a]pyrazines: orally efficacious inhibitors of mTORC1 and mTORC2. | Bioorganic & medicinal chemistry letters 20110401 |
| Novel approaches for preventing or limiting events in diabetic patients (Naples-diabetes) trial: a randomized comparison of 3 drug-eluting stents in diabetic patients. | Circulation. Cardiovascular interventions 20110401 |
| Comparison of zotarolimus-eluting stents with sirolimus-eluting and paclitaxel-eluting stents: intimal hyperplasia and vascular changes assessed by volumetric intravascular ultrasound analysis. | Circulation. Cardiovascular interventions 20110401 |
| Rapamycin-mediated mTOR inhibition attenuates survivin and sensitizes glioblastoma cells to radiation therapy. | Acta biochimica et biophysica Sinica 20110401 |
| Intravascular ultrasound results from the NEVO ResElution-I trial: a randomized, blinded comparison of sirolimus-eluting NEVO stents with paclitaxel-eluting TAXUS Liberté stents in de novo native coronary artery lesions. | Circulation. Cardiovascular interventions 20110401 |
| The physiology and pathophysiology of rapamycin resistance: implications for cancer. | Cell cycle (Georgetown, Tex.) 20110401 |
| A brief history of TOR. | Biochemical Society transactions 20110401 |
| Differing effects of rapamycin and mTOR kinase inhibitors on protein synthesis. | Biochemical Society transactions 20110401 |
| Blocking the mTOR pathway: a drug discovery perspective. | Biochemical Society transactions 20110401 |
| Benefits of mTOR kinase targeting in oncology: pre-clinical evidence with AZD8055. | Biochemical Society transactions 20110401 |
| A critical role for non-coding RNA GAS5 in growth arrest and rapamycin inhibition in human T-lymphocytes. | Biochemical Society transactions 20110401 |
| Fragile X mental retardation protein regulates heterosynaptic plasticity in the hippocampus. | Learning & memory (Cold Spring Harbor, N.Y.) 20110401 |
| Temsirolimus and rituximab in patients with relapsed or refractory mantle cell lymphoma: a phase 2 study. | The Lancet. Oncology 20110401 |
| New combinations for mantle cell lymphoma: concerted action needed. | The Lancet. Oncology 20110401 |
| Paradoxical aspects of rapamycin immunobiology in transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110401 |
| Two drug interaction studies of sirolimus in combination with sorafenib or sunitinib in patients with advanced malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110401 |
| Can the nephron be spared? | Kidney international 20110401 |
| [Treatment of metastatic renal cell carcinoma]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20110401 |
| Next-generation mTOR inhibitors in clinical oncology: how pathway complexity informs therapeutic strategy. | The Journal of clinical investigation 20110401 |
| Vulnerable plaque inside stent. | JACC. Cardiovascular imaging 20110401 |
| Restenosis: delineating the numerous causes of drug-eluting stent restenosis. | Circulation. Cardiovascular interventions 20110401 |
| The prognostic utility of the SYNTAX score on 1-year outcomes after revascularization with zotarolimus- and everolimus-eluting stents: a substudy of the RESOLUTE All Comers Trial. | JACC. Cardiovascular interventions 20110401 |
| Randomized comparison of a polymer-free sirolimus-eluting stent versus a polymer-based paclitaxel-eluting stent in patients with diabetes mellitus: the LIPSIA Yukon trial. | JACC. Cardiovascular interventions 20110401 |
| Five-year outcomes of percutaneous coronary intervention compared to bypass surgery in patients with multivessel disease involving the proximal left anterior descending artery: an ARTS-II sub-study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110401 |
| Comparison between the first and second generation bioresorbable vascular scaffolds: a six month virtual histology study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110401 |
| [Late thrombosis of sirolimus-eluting stent occurring in the perioperative period]. | Masui. The Japanese journal of anesthesiology 20110401 |
| [Use of mTOR-inhibitors in solid tumors]. | Medizinische Monatsschrift fur Pharmazeuten 20110401 |
| Comparison of long-term clinical outcome after successful implantation of FIREBIRD and CYPHER sirolimus-eluting stents in daily clinical practice: analysis of a large single-center registry. | Chinese medical journal 20110401 |
| Technical difficulty in stenting Supralimus in radial artery graft. | Arquivos brasileiros de cardiologia 20110401 |
| [Effect of rapamycin combined with cisplatin on head and neck squamous cancer cells regulated by CCL19]. | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20110401 |
| mTOR inhibitors in the treatment of subependymal giant-cell astrocytomas associated with tuberous sclerosis. | Neurosurgery 20110401 |
| Ribosomal protein S6 is highly expressed in non-Hodgkin lymphoma and associates with mRNA containing a 5' terminal oligopyrimidine tract. | Oncogene 20110331 |
| Targeting the autophagy pathway using ectopic expression of Beclin 1 in combination with rapamycin in drug-resistant v-Ha-ras-transformed NIH 3T3 cells. | Molecules and cells 20110331 |
| Stent thrombosis and bleeding complications after implantation of sirolimus-eluting coronary stents in an unselected worldwide population: a report from the e-SELECT (Multi-Center Post-Market Surveillance) registry. | Journal of the American College of Cardiology 20110329 |
| Paclitaxel/sirolimus combination coated drug-eluting stent: in vitro and in vivo drug release studies. | Journal of pharmaceutical and biomedical analysis 20110325 |
| Drug-eluting or bare-metal stents in large coronary arteries. | The New England journal of medicine 20110324 |
| Chromophobe renal cell carcinoma with prolonged response to sequential sunitinib and everolimus. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110320 |
| Autophagy controls IL-1beta secretion by targeting pro-IL-1beta for degradation. | The Journal of biological chemistry 20110318 |
| Translational medicine: Cancer lessons from mice to humans. | Nature 20110317 |
| Long-term (three-year) safety and efficacy of everolimus-eluting stents compared to paclitaxel-eluting stents (from the SPIRIT III Trial). | The American journal of cardiology 20110315 |
| Three-year results of safety and efficacy of the everolimus-eluting coronary stent in women (from the SPIRIT III randomized clinical trial). | The American journal of cardiology 20110315 |
| MAP kinase-interacting kinase 1 regulates SMAD2-dependent TGF-β signaling pathway in human glioblastoma. | Cancer research 20110315 |
| Engineering the ABA plant stress pathway for regulation of induced proximity. | Science signaling 20110315 |
| [Rapamycin-mediated interaction of spleen γδT lymphocytes and lung macrophages in acute lung injury of mice induced by lipopolysaccharide]. | Zhonghua yi xue za zhi 20110315 |
| Sindbis virus replication, is insensitive to rapamycin and torin1, and suppresses Akt/mTOR pathway late during infection in HEK cells. | Biochemical and biophysical research communications 20110311 |
| Pancreatic neuroendocrine tumors: role of novel agents. Highlights from the '2011 ASCO Gastrointestinal Cancers Symposium'. San Francisco, CA, USA. January 20-22, 2011. | JOP : Journal of the pancreas 20110309 |
| Everolimus-based, calcineurin-inhibitor-free regimen in recipients of de-novo kidney transplants: an open-label, randomised, controlled trial. | Lancet (London, England) 20110305 |
| Immunosuppression without calcineurin inhibition: by ZEUS. | Lancet (London, England) 20110305 |
| Stent fracture and restenosis after zotarolimus-eluting stent implantation. | International journal of cardiology 20110303 |
| Long-term safety and efficacy of sirolimus- vs. paclitaxel-eluting stent implantation for acute ST-elevation myocardial infarction: 3-year follow-up of the PROSIT trial. | International journal of cardiology 20110303 |
| Autophagy modification augmented the treatment effects initiated by arsenic trioxide in NB4 cells. | Medical oncology (Northwood, London, England) 20110301 |
| Leucine supplementation in rats induced a delay in muscle IR/PI3K signaling pathway associated with overall impaired glucose tolerance. | The Journal of nutritional biochemistry 20110301 |
| Comparative assessment of mammalian target of rapamycin inhibitor-eluting stents in the treatment of coronary artery bifurcation lesions: the CASTOR-Bifurcation registry. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301 |
| Hypoxia-inducible factor and mammalian target of rapamycin pathway markers in urothelial carcinoma of the bladder: possible therapeutic implications. | BJU international 20110301 |
| Radiologic complete response with sirolimus and sorafenib in a hepatocellular carcinoma patient who relapsed after orthotopic liver transplantation. | Journal of gastrointestinal cancer 20110301 |
| Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic β-cells: protective role of p62-positive cytoplasmic inclusions. | Cell death and differentiation 20110301 |
| Leukemias induced by altered TRK-signaling are sensitive to mTOR inhibitors in preclinical models. | Annals of hematology 20110301 |
| Five-year clinical outcomes of sirolimus-eluting versus paclitaxel-eluting stents in high-risk patients. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301 |
| Zebrafish model of tuberous sclerosis complex reveals cell-autonomous and non-cell-autonomous functions of mutant tuberin. | Disease models & mechanisms 20110301 |
| Long-term angiographic outcomes of post-sirolimus-eluting stent restenosis in Japanese patients. | Heart and vessels 20110301 |
| mTOR and rapamycin in the kidney: signaling and therapeutic implications beyond immunosuppression. | Kidney international 20110301 |
| Rapamycin increases the yield and effector function of human γδ T cells stimulated in vitro. | Cancer immunology, immunotherapy : CII 20110301 |
| Angiographic late lumen loss at the site of overlap of multiple Cypher™ sirolimus-eluting stents: ALSOCE study. | Journal of cardiology 20110301 |
| Diaphragm rupture in a liver transplant patient under chronic immunosuppressive therapy with sirolimus: rare complication after liver transplantation. | Updates in surgery 20110301 |
| Pushing the envelope in the mTOR pathway: the second generation of inhibitors. | Molecular cancer therapeutics 20110301 |
| Heat stress enhances mTOR signaling after resistance exercise in human skeletal muscle. | The journal of physiological sciences : JPS 20110301 |
| The double-faced metabolic and inflammatory effects of standard drug therapy in patients after percutaneous treatment with drug-eluting stent. | Atherosclerosis 20110301 |
| mTOR inhibitors show promising in vitro activity in bladder cancer and head and neck squamous cell carcinoma. | Oncology reports 20110301 |
| mTOR couples cellular nutrient sensing to organismal metabolic homeostasis. | Trends in endocrinology and metabolism: TEM 20110301 |
| Regulatory T cells require mammalian target of rapamycin signaling to maintain both homeostasis and alloantigen-driven proliferation in lymphocyte-replete mice. | Journal of immunology (Baltimore, Md. : 1950) 20110301 |
| Current and future directions in mammalian target of rapamycin inhibitors development. | Expert opinion on investigational drugs 20110301 |
| Biolimus-eluting biodegradable polymer-coated stent versus bare metal stent in acute ST-elevation and non-ST elevation myocardial infarction: Justification for biodegradable polymer-coated stent in acute coronary syndrome (JANICE) registry. | Acute cardiac care 20110301 |
| Cyclosporin A, but not everolimus, inhibits DNA repair mediated by calcineurin: implications for tumorigenesis under immunosuppression. | Experimental dermatology 20110301 |
| The outcome of bifurcation lesion stenting using a biolimus-eluting stent with a bio-degradable polymer compared to a sirolimus-eluting stent with a durable polymer. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110301 |
| Rapamycin reverses hypertrophic cardiomyopathy in a mouse model of LEOPARD syndrome-associated PTPN11 mutation. | The Journal of clinical investigation 20110301 |
| Analytical and pharmacological aspects of therapeutic drug monitoring of mTOR inhibitors. | Current drug metabolism 20110301 |
| Sirolimus enhances the magnitude and quality of viral-specific CD8+ T-cell responses to vaccinia virus vaccination in rhesus macaques. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110301 |
| Weekly bortezomib in combination with temsirolimus in relapsed or relapsed and refractory multiple myeloma: a multicentre, phase 1/2, open-label, dose-escalation study. | The Lancet. Oncology 20110301 |
| If I've heard it once, I've heard it (not yet) a hundred times. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301 |
| Primary percutaneous coronary intervention of an unprotected left main using mini-crush drug-eluting stents facilitated by intracoronary reteplase. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110301 |
| Noninfectious pneumonitis in a patient with renal cell carcinoma treated with everolimus. | Oncology nursing forum 20110301 |
| Reduced VEGF production, angiogenesis, and vascular regrowth contribute to the antitumor properties of dual mTORC1/mTORC2 inhibitors. | Cancer research 20110301 |
| Ruptured-plaque-like appearance of restenotic tissue following sirolimus-eluting stent implantation: an optical coherence tomography case study. | The Journal of invasive cardiology 20110301 |
| CYP3A5 genotype does not influence everolimus in vitro metabolism and clinical pharmacokinetics in renal transplant recipients. | Transplantation 20110301 |
| Potential of mTOR inhibitors for the treatment of subependymal giant cell astrocytomas in tuberous sclerosis complex. | Aging 20110301 |
| A randomized comparison of sirolimus- versus paclitaxel-eluting stent implantation in patients with diabetes mellitus: 4-year clinical outcomes of DES-DIABETES (drug-eluting stent in patients with DIABETES mellitus) trial. | JACC. Cardiovascular interventions 20110301 |
| Prospective randomized comparison of sirolimus- or everolimus-eluting stent to treat bifurcated lesions by provisional approach. | JACC. Cardiovascular interventions 20110301 |
| Steroid and calcineurin inhibitor-sparing protocols in kidney transplantation. | Transplantation proceedings 20110301 |
| Conversion to low-dose tacrolimus or rapamycin 3 months after kidney transplantation: a prospective, protocol biopsy-guided study. | Transplantation proceedings 20110301 |
| Rapamycin prevents interstitial fibrosis in renal allografts through decreasing angiogenesis and inflammation. | Transplantation proceedings 20110301 |
| Exploring long-term protection of normal human fibroblasts and epithelial cells from chemotherapy in cell culture. | Oncotarget 20110301 |
| Future directions of mammalian target of rapamycin (mTOR) inhibitor therapy in renal cell carcinoma. | Targeted oncology 20110301 |
| Spatial distribution of neo-intimal hyperplasia 6 months after zotarolimus-eluting stent implantation, analysed by optical coherence tomography. | Archives of cardiovascular diseases 20110301 |
| Mammalian target of rapamycin as a target in hematological malignancies. | Targeted oncology 20110301 |
| A prospective multicenter parallel-controlled trial of TIVOLI biodegradable-polymer-based sirolimus-eluting stent compared to ENDEAVOR zotarolimus-eluting stent for the treatment of coronary artery disease: 8-month angiographic and 2-year clinical follow-up results. | Chinese medical journal 20110301 |
| Efficacy and safety of Firebird sirolimus-eluting stent in treatment of complex coronary lesions in Chinese patients: one-year clinical and eight-month angiographic outcomes from the FIREMAN registry. | Chinese medical journal 20110301 |
| Six-month clinical outcomes of Firebird 2TM sirolimus-eluting stent implantation in real-world patients with coronary artery diseases. | Chinese medical journal 20110301 |
| Long-term effects of biodegradable versus durable polymer-coated sirolimus-eluting stents on coronary arterial wall morphology assessed by virtual histology intravascular ultrasound. | Chinese medical journal 20110301 |
| Targeting the target of rapamycin (TOR): looking to mother nature. | Targeted oncology 20110301 |
| The emerging role of mammalian target of rapamycin inhibitors in the treatment of sarcomas. | Targeted oncology 20110301 |
| [Effect of daunorubicin and rapamycin combination on the proliferation of acute leukemia cells]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110301 |
| Mechanisms of mTOR inhibitor resistance in cancer therapy. | Targeted oncology 20110301 |
| [Current status in molecular-targeted therapy and IFNα for renal cell carcinoma in Japan]. | Hinyokika kiyo. Acta urologica Japonica 20110301 |
| [Determination of the content of zotarolimus on the drug eluting stents by HPLC]. | Zhongguo yi liao qi xie za zhi = Chinese journal of medical instrumentation 20110301 |
| Resveratrol enhances the anti-tumor activity of the mTOR inhibitor rapamycin in multiple breast cancer cell lines mainly by suppressing rapamycin-induced AKT signaling. | Cancer letters 20110227 |
| Embryonic pig pancreatic tissue for the treatment of diabetes: potential role of immune suppression with 'off-the-shelf' third-party regulatory T cells. | Transplantation 20110227 |
| Inhibitory effects of the HDAC inhibitor valproic acid on prostate cancer growth are enhanced by simultaneous application of the mTOR inhibitor RAD001. | Life sciences 20110227 |
| mTOR-dependent regulation of PHLPP expression controls the rapamycin sensitivity in cancer cells. | The Journal of biological chemistry 20110225 |
| A randomized clinical study comparing double kissing crush with provisional stenting for treatment of coronary bifurcation lesions: results from the DKCRUSH-II (Double Kissing Crush versus Provisional Stenting Technique for Treatment of Coronary Bifurcation Lesions) trial. | Journal of the American College of Cardiology 20110222 |
| mTOR inhibitor treatment of pancreatic cancer in a patient With Peutz-Jeghers syndrome. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20110220 |
| Use of drug-eluting stents for chronic total occlusions: a systematic review and meta-analysis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110215 |
| FOXO3a reactivation mediates the synergistic cytotoxic effects of rapamycin and cisplatin in oral squamous cell carcinoma cells. | Toxicology and applied pharmacology 20110215 |
| Combination mTOR and IGF-1R inhibition: phase I trial of everolimus and figitumumab in patients with advanced sarcomas and other solid tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110215 |
| Two-year safety and effectiveness of sirolimus-eluting stents (from a prospective registry). | The American journal of cardiology 20110215 |
| Temsirolimus, an mTOR inhibitor, enhances anti-tumour effects of heat shock protein cancer vaccines. | British journal of cancer 20110215 |
| Calcineurin inhibitor-free monotherapy in human leukocyte antigen–identical live donor renal transplantation. | Transplantation 20110215 |
| Perivascular sirolimus-delivery system. | International journal of pharmaceutics 20110214 |
| Everolimus for advanced pancreatic neuroendocrine tumors. | The New England journal of medicine 20110210 |
| Promising advances in the treatment of malignant pancreatic endocrine tumors. | The New England journal of medicine 20110210 |
| Everolimus and giant-cell astrocytomas in tuberous sclerosis. | The New England journal of medicine 20110210 |
| Everolimus and giant-cell astrocytomas in tuberous sclerosis. | The New England journal of medicine 20110210 |
| Spinal phosphinositide 3-kinase-Akt-mammalian target of rapamycin signaling cascades in inflammation-induced hyperalgesia. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110209 |
| Rapamycin suppresses mossy fiber sprouting but not seizure frequency in a mouse model of temporal lobe epilepsy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110209 |
| Sirolimus eluting stent restenosis: impact of angiographic patterns and the treatment factors on angiographic outcomes in contemporary practice. | International journal of cardiology 20110203 |
| Disrupting function of FK506-binding protein 1b/12.6 induces the Ca²+-dysregulation aging phenotype in hippocampal neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110202 |
| Early graft dysfunction in a child with renal transplantation. | Pediatric nephrology (Berlin, Germany) 20110201 |
| mTOR partly mediates insulin resistance by phosphorylation of insulin receptor substrate-1 on serine(307) residues after burn. | Burns : journal of the International Society for Burn Injuries 20110201 |
| Integrating bevacizumab, everolimus, and lapatinib into current neoadjuvant chemotherapy regimen for primary breast cancer. Safety results of the GeparQuinto trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20110201 |
| The PI3K/Akt/mTOR pathway is activated in murine lupus nephritis and downregulated by rapamycin. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110201 |
| Comparison of sirolimus with azathioprine in a tacrolimus-based immunosuppressive regimen in lung transplantation. | American journal of respiratory and critical care medicine 20110201 |
| National Cancer Institute pediatric preclinical testing program: model description for in vitro cytotoxicity testing. | Pediatric blood & cancer 20110201 |
| Increased risk of venous thromboembolism with a sirolimus-based immunosuppression regimen in lung transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20110201 |
| Aging and TOR: interwoven in the fabric of life. | Cellular and molecular life sciences : CMLS 20110201 |
| Comparison of blood sirolimus, tacrolimus and everolimus concentrations measured by LC-MS/MS, HPLC-UV and immunoassay methods. | Clinical biochemistry 20110201 |
| Rapamycin, but not resveratrol or simvastatin, extends life span of genetically heterogeneous mice. | The journals of gerontology. Series A, Biological sciences and medical sciences 20110201 |
| Beta cell function during rapamycin monotherapy in long-term type 1 diabetes. | Diabetologia 20110201 |
| Vertical inhibition of the mTORC1/mTORC2/PI3K pathway shows synergistic effects against melanoma in vitro and in vivo. | The Journal of investigative dermatology 20110201 |
| Antagonistic interactions between the cAMP-dependent protein kinase and Tor signaling pathways modulate cell growth in Saccharomyces cerevisiae. | Genetics 20110201 |
| A phase I study of bevacizumab (B) in combination with everolimus (E) and erlotinib (E) in advanced cancer (BEE). | Cancer chemotherapy and pharmacology 20110201 |
| Evidence for the involvement of mTOR inhibition and basal autophagy in familial Mediterranean fever phenotype. | Human immunology 20110201 |
| Caffeine induces apoptosis by enhancement of autophagy via PI3K/Akt/mTOR/p70S6K inhibition. | Autophagy 20110201 |
| Dissecting the dynamic turnover of GFP-LC3 in the autolysosome. | Autophagy 20110201 |
| mTOR inhibitors and sorafenib for recurrent heptocellular carcinoma after orthotopic liver transplantation. | Journal of hepatology 20110201 |
| Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders. | Trends in molecular medicine 20110201 |
| Combined targeting of the VEGFr/EGFr and the mammalian target of rapamycin (mTOR) signaling pathway delays cell cycle progression and alters adhesion behavior of prostate carcinoma cells. | Cancer letters 20110201 |
| A comparative assessment by optical coherence tomography of the performance of the first and second generation of the everolimus-eluting bioresorbable vascular scaffolds. | European heart journal 20110201 |
| Autophagy aids membrane expansion by neuropathic Schwann cells. | Autophagy 20110201 |
| A phase II trial of the oral mTOR inhibitor everolimus in relapsed aggressive lymphoma. | Leukemia 20110201 |
| Clinical safety and efficacy of everolimus-eluting stents compared to paclitaxel-eluting stents in patients with coronary artery disease. | Annals of medicine 20110201 |
| Loss of canonical insulin signaling accelerates vascular smooth muscle cell proliferation and migration through changes in p27Kip1 regulation. | Endocrinology 20110201 |
| Systemic influence of immunosuppressive drugs on small and large bowel transport and barrier function. | Transplant international : official journal of the European Society for Organ Transplantation 20110201 |
| Interpreting mammalian target of rapamycin and cell growth inhibition in a genetically engineered mouse model of Nf1-deficient astrocytes. | Molecular cancer therapeutics 20110201 |
| Influence of age on the clinical outcomes of coronary revascularisation for the treatment of patients with multivessel de novo coronary artery lesions: sirolimus-eluting stent vs. coronary artery bypass surgery and bare metal stent, insight from the multicentre randomised Arterial Revascularisation Therapy Study Part I (ARTS-I) and Part II (ARTS-II). | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110201 |
| Infected coronary artery pseudoaneurysm after repeated percutaneous coronary intervention. | The Annals of thoracic surgery 20110201 |
| Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling. | European journal of immunology 20110201 |
| The mTOR inhibitor rapamycin suppresses DNA double-strand break repair. | Radiation research 20110201 |
| Randomized comparison of percutaneous coronary intervention with sirolimus-eluting stents versus coronary artery bypass grafting in unprotected left main stem stenosis. | Journal of the American College of Cardiology 20110201 |
| Total recall of radiotherapy with mTOR inhibitors: a novel and potentially frequent side-effect? | Annals of oncology : official journal of the European Society for Medical Oncology 20110201 |
| Very late thrombosis of sirolimus-eluting stent despite dual antiplatelet therapy for 4 years in a patient with lung cancer. | Minerva cardioangiologica 20110201 |
| Tailoring immunosuppressive therapy for lung transplantation: moving beyond hand-me-down data. | American journal of respiratory and critical care medicine 20110201 |
| Procedural and clinical evaluation of the novel zotarolimus-eluting resolute stent in patients with unselected bifurcated coronary stenosis treated by provisional approach: a multicenter registry. | The Journal of invasive cardiology 20110201 |
| Resolute™ drug-eluting stent: a resolution for bifurcation lesions? | The Journal of invasive cardiology 20110201 |
| Primary everolimus-eluting stenting versus balloon angioplasty with bailout bare metal stenting of long infrapopliteal lesions for treatment of critical limb ischemia. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20110201 |
| Targeted therapies for the treatment of metastatic renal cell carcinoma: clinical evidence. | The oncologist 20110201 |
| Beyond traditional outcomes: improving quality of life in patients with renal cell carcinoma. | The oncologist 20110201 |
| Treatment-associated adverse event management in the advanced renal cell carcinoma patient treated with targeted therapies. | The oncologist 20110201 |
| Effectiveness of paclitaxel-eluting balloon catheter in patients with sirolimus-eluting stent restenosis. | JACC. Cardiovascular interventions 20110201 |
| The SPIRIT V study: a clinical evaluation of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions. | JACC. Cardiovascular interventions 20110201 |
| Signaling to the ribosome in cancer--It is more than just mTORC1. | IUBMB life 20110201 |
| [Types and characteristic features of drug-eluting stents]. | Nihon rinsho. Japanese journal of clinical medicine 20110201 |
| Ten-month laryngeal allograft survival with use of pulsed everolimus and anti-alphabeta T-cell receptor antibody immunosuppression. | The Annals of otology, rhinology, and laryngology 20110201 |
| Conversion from cyclosporine to sirolimus in chronic renal allograft dysfunction: a 4-year prospective study. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20110201 |
| Immunosuppressive therapy in children. | Journal of the Indian Medical Association 20110201 |
| Rapamycin treatment causes developmental delay, pigmentation defects, and gastrointestinal malformation on Xenopus embryogenesis. | Biochemical and biophysical research communications 20110128 |
| Allospecific regulatory effects of sirolimus and tacrolimus in the human mixed lymphocyte reaction. | Transplantation 20110127 |
| Light regulation of protein dimerization and kinase activity in living cells using photocaged rapamycin and engineered FKBP. | Journal of the American Chemical Society 20110126 |
| Coronary responses and differential mechanisms of late stent thrombosis attributed to first-generation sirolimus- and paclitaxel-eluting stents. | Journal of the American College of Cardiology 20110125 |
| Sirolimus- versus paclitaxel-eluting stents in patients with acute myocardial infarction: a meta-analysis of randomized trials. | International journal of cardiology 20110121 |
| Randomized study on provisional stenting with sirolimus-eluting stent vs. bare metal stent for the treatment of true coronary bifurcations: the PROSUMER (PROvisional with sirolimus-eluting vs. bare metal stents in truE bifuRcations) study. | International journal of cardiology 20110121 |
| Translation of 5' terminal oligopyrimidine tract (5'TOP) mRNAs in Aplysia Californica is regulated by the target of rapamycin (TOR). | Biochemical and biophysical research communications 20110121 |
| mTOR inhibitors and autosomal dominant polycystic kidney disease. | The New England journal of medicine 20110120 |
| mTOR inhibitors and autosomal dominant polycystic kidney disease. | The New England journal of medicine 20110120 |
| mTOR inhibitors and autosomal dominant polycystic kidney disease. | The New England journal of medicine 20110120 |
| Protective effect of immunosuppressive treatment before orthotopic kidney autotransplantation. | Transplant immunology 20110115 |
| Adoptive transfer of DNT cells induces long-term cardiac allograft survival and augments recipient CD4(+)Foxp3(+) Treg cell accumulation. | Transplant immunology 20110115 |
| Haplotypic arrangement in CYP3A locus is associated with side effects of proliferative signal inhibitors in renal transplant recipients. | Transplantation 20110115 |
| Mean glomerular volume after renal transplantation in patients receiving sirolimus and cyclosporine a compared with elimination of cyclosporine a at 3 months. | Transplantation 20110115 |
| Switching to sirolimus-based immune suppression after liver transplantation is safe and effective: a single-center experience. | Transplantation 20110115 |
| Multi-timescale dynamics study of FKBP12 along the rapamycin-mTOR binding coordinate. | Journal of molecular biology 20110114 |
| Inhibition of the mammalian target of rapamycin pathway by rapamycin blocks cocaine-induced locomotor sensitization. | Neuroscience 20110113 |
| Pipecolic acid derivatives as small-molecule inhibitors of the Legionella MIP protein. | Journal of medicinal chemistry 20110113 |
| A photocleavable rapamycin conjugate for spatiotemporal control of small GTPase activity. | Journal of the American Chemical Society 20110112 |
| Identification of FUSE-binding protein 1 as a regulatory mRNA-binding protein that represses nucleophosmin translation. | Oncogene 20110106 |
| α-TEA cooperates with MEK or mTOR inhibitors to induce apoptosis via targeting IRS/PI3K pathways. | British journal of cancer 20110104 |
| mTOR-mediated dedifferentiation of the retinal pigment epithelium initiates photoreceptor degeneration in mice. | The Journal of clinical investigation 20110104 |
| Coronary angiography and computed tomography angiography in the diagnosis of extrinsic compression of left internal mammary artery. | Journal of cardiovascular medicine (Hagerstown, Md.) 20110101 |
| The role of CYP3A5 genotypes in dose requirements of tacrolimus and everolimus after heart transplantation. | Clinical transplantation 20110101 |
| Inhibitors of phosphatidylinositol 3-kinase and mTOR but not Akt enhance replication of bovine ephemeral fever virus. | Veterinary journal (London, England : 1997) 20110101 |
| Randomized, double-blind, placebo-controlled, single intravenous dose-escalation study to evaluate the safety, tolerability, and pharmacokinetics of the novel coronary smooth muscle cell proliferation inhibitor Biolimus A9 in healthy individuals. | Journal of clinical pharmacology 20110101 |
| Inhibition of bladder tumour growth by sirolimus in an experimental carcinogenesis model. | BJU international 20110101 |
| Impressive response to temsirolimus in a patient with chemotherapy refractory diffuse large B-cell non-Hodgkin's lymphoma. | Annals of hematology 20110101 |
| Steroid minimization for sirolimus-treated renal transplant recipients. | Clinical transplantation 20110101 |
| First nine-month complete invasive assessment (angiography, IVUS, and OCT) of the novel NEVO sirolimus-eluting stent with biodegradable polymer. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101 |
| Sirolimus versus paclitaxel coronary stents in clinical practice. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101 |
| Everolimus and PTK/ZK show synergistic growth inhibition in the orthotopic BL16/BL6 murine melanoma model. | Cancer chemotherapy and pharmacology 20110101 |
| Temsirolimus in VEGF-refractory metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20110101 |
| Inhibition of mTOR with sirolimus does not attenuate progression of liver and kidney disease in PCK rats. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110101 |
| Calcineurin inhibitor sparing regimens using m-target of rapamycin inhibitors: an opportunity to improve cardiovascular risk following kidney transplantation? | Transplant international : official journal of the European Society for Organ Transplantation 20110101 |
| Regression of subependymal giant cell astrocytomas with RAD001 (Everolimus) in tuberous sclerosis complex. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20110101 |
| Activation of mTOR and RhoA is a major mechanism by which Ceramide 1-phosphate stimulates macrophage proliferation. | Cellular signalling 20110101 |
| Mammalian target of rapamycin (mTOR) phosphorylates inositol 1,4,5-trisphosphate receptor type 2 and increases its Ca(2+) release activity. | Cellular signalling 20110101 |
| Select nutrients in the ovine uterine lumen. VII. Effects of arginine, leucine, glutamine, and glucose on trophectoderm cell signaling, proliferation, and migration. | Biology of reproduction 20110101 |
| Differential modulation of the cytokine-induced MMP-9/TIMP-1 protease-antiprotease system by the mTOR inhibitor rapamycin. | Biochemical pharmacology 20110101 |
| Vitamin K3 attenuates cerulein-induced acute pancreatitis through inhibition of the autophagic pathway. | Pancreas 20110101 |
| Evaluation of the mTOR inhibitor, everolimus, in combination with cytotoxic antitumor agents using human tumor models in vitro and in vivo. | Anti-cancer drugs 20110101 |
| Angiographic and intravascular ultrasound follow up of paclitaxel- and sirolimus-eluting stent after poststent high-pressure balloon dilation: from the poststent optimal stent expansion trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101 |
| Oral sirolimus after bare metal stent implantation: a glimpse to the future. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101 |
| Activation of STAT1 is required for interferon-alpha-mediated cell death. | Experimental cell research 20110101 |
| mTORC1/2 and rapamycin in female Han:SPRD rats with polycystic kidney disease. | American journal of physiology. Renal physiology 20110101 |
| Enhanced sensitivity to rapamycin following long-term oestrogen deprivation in MCF-7, T-47-D and ZR-75-1 human breast cancer cells. | The Journal of endocrinology 20110101 |
| The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia. | Haematologica 20110101 |
| Sirolimus damages podocytes in rats with protein overload nephropathy. | Journal of nephrology 20110101 |
| Phase III trial of everolimus in metastatic renal cell carcinoma: subgroup analysis of Japanese patients from RECORD-1. | Japanese journal of clinical oncology 20110101 |
| Identification of clinically used drugs that activate pregnane X receptors. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
| Long-term outcome of sirolimus-eluting stent implantation for left main coronary artery stenosis in infancy. | Pediatric cardiology 20110101 |
| Antibacterial autophagy occurs at PI(3)P-enriched domains of the endoplasmic reticulum and requires Rab1 GTPase. | Autophagy 20110101 |
| Deciphering the signaling pathways of cancer stem cells of glioblastoma multiforme: role of Akt/mTOR and MAPK pathways. | Advances in enzyme regulation 20110101 |
| Partial graft recovery following eradication of hepatitis E virus infection after successful islet allograft transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20110101 |
| Assessment by optical coherence tomography of stent struts across side branch. -Comparison of bare-metal stents and drug-elution stents.-. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Age and sex differences in the effects of the immunosuppressants cyclosporine, sirolimus and everolimus on rat brain metabolism. | Neurotoxicology 20110101 |
| Albuminuria after renal transplantation: maintenance with sirolimus/low-dose tacrolimus vs. mycophenolate mofetil/high-dose tacrolimus. | Clinical transplantation 20110101 |
| Drug-eluting stents for the treatment of pulmonary vein stenosis after atrial fibrillation ablation. | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology 20110101 |
| Impact of cytochrome P450 2C19*2 polymorphism on intra-stent thrombus after drug-eluting stent implantation in Japanese patients receiving clopidogrel. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Predictors of stent fracture in patients treated with closed-cell design stents: sirolimus-eluting stent and its bare-metal counterpart, the BX velocity stent. | Coronary artery disease 20110101 |
| Phase I trial of oral mTOR inhibitor everolimus in combination with trastuzumab and vinorelbine in pre-treated patients with HER2-overexpressing metastatic breast cancer. | Breast cancer research and treatment 20110101 |
| Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2. | The FEBS journal 20110101 |
| Immunosuppression with belatacept-based, corticosteroid-avoiding regimens in de novo kidney transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20110101 |
| The relationship between late lumen loss and restenosis among various drug-eluting stents: a systematic review and meta-regression analysis of randomized clinical trials. | Atherosclerosis 20110101 |
| Mechanisms mediating the cardioprotective effects of rapamycin in ischaemia-reperfusion injury. | Clinical and experimental pharmacology & physiology 20110101 |
| Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway. | The FEBS journal 20110101 |
| AP-1 regulates cyclin D1 and c-MYC transcription in an AKT-dependent manner in response to mTOR inhibition: role of AIP4/Itch-mediated JUNB degradation. | Molecular cancer research : MCR 20110101 |
| Evaluation of the novel protein kinase C inhibitor sotrastaurin as immunosuppressive therapy after renal transplantation. | Expert opinion on drug metabolism & toxicology 20110101 |
| Retrospective comparison of clinical and angiographic outcomes after primary stenting using sirolimus-eluting and bare-metal stents in nonrandomized consecutive 568 patients with first ST-segment elevated myocardial infarctions. | Journal of cardiology 20110101 |
| Tolerability of everolimus-based immunosuppression in maintenance liver transplant recipients. | Clinical transplantation 20110101 |
| Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. | European journal of heart failure 20110101 |
| Control of carcinoid syndrome with everolimus. | Annals of oncology : official journal of the European Society for Medical Oncology 20110101 |
| Clinical and angiographic outcomes with sirolimus-eluting stent for coronary bifurcation lesions. The J-PMS study. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Drug-eluting stents vs. bare metal stents in saphenous vein graft disease. Insights from a meta-analysis of 7,090 patients. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Neointimal coverage over coronary stent struts crossing the side branch Ostia. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Prolonged survival in renal transplant recipient with advanced renal cell carcinoma by everolimus and sorafenib. | Nephrology (Carlton, Vic.) 20110101 |
| Everolimus: a new mammalian target of rapamycin inhibitor for the treatment of advanced renal cell carcinoma. | The Annals of pharmacotherapy 20110101 |
| Sirolimus- versus paclitaxel-eluting stents for unselected patients with coronary artery disease. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101 |
| Nevo stent: a successful stent makeover. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20110101 |
| Tuberous sclerosis complex: tumors and tumorigenesis. | International journal of dermatology 20110101 |
| Protein kinase B/Akt regulation in diabetic kidney disease. | Frontiers in bioscience (Scholar edition) 20110101 |
| Drug interaction between rifampicin and sirolimus in transplant patients. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20110101 |
| Medical management of skin disease: recent advances and future directions. | Journal of drugs in dermatology : JDD 20110101 |
| Sirolimus-eluting stent implantation versus beta-irradiation for the treatment of in-stent restenotic lesions: clinical and ultrasound results from a randomised trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110101 |
| Drug eluting stents for the treatment of bare metal in-stent restenosis: long-term outcomes in real world practice. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110101 |
| Clinical usefulness of drug-eluting stents in the treatment of dialysis patients with coronary artery disease. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20110101 |
| The mTOR kinase inhibitor rapamycin decreases iNOS mRNA stability in astrocytes. | Journal of neuroinflammation 20110101 |
| Clinical characteristics of coronary drug-eluting stent fracture: insights from a two-center des registry. | Journal of Korean medical science 20110101 |
| Therapeutic targeting the loss of the birt-hogg-dube suppressor gene. | Molecular cancer therapeutics 20110101 |
| Targeting the PI3K/mTOR pathway in murine endocrine cell lines: in vitro and in vivo effects on tumor cell growth. | The American journal of pathology 20110101 |
| Conditional depletion of nuclear proteins by the Anchor Away system. | Current protocols in molecular biology 20110101 |
| The final answer? For the treatment of saphenous vein graft disease, drug-eluting stents vs. bare-metal stents. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Two-dose-level confirmatory study of the pharmacokinetics and tolerability of everolimus in Chinese patients with advanced solid tumors. | Journal of hematology & oncology 20110101 |
| Two-year outcome of Turkish patients treated with Zotarolimus versus Paclitaxel eluting stents in an unselected population with coronary artery disease in the real world: a prospective non-randomized registry in southern Turkey. | International journal of medical sciences 20110101 |
| Selective inhibition of cyclooxygenase-2 suppresses metastatic disease without affecting primary tumor growth in a murine model of Ewing sarcoma. | Journal of pediatric surgery 20110101 |
| Good outcomes with cyclosporine very low exposure with everolimus high exposure in renal transplant patients. | Journal of nephrology 20110101 |
| Late stent thrombosis secondary to carbon monoxide poisoning. | Cardiovascular revascularization medicine : including molecular interventions 20110101 |
| Everolimus resolving hypoglycemia, producing hyperglycemia, and necessitating insulin use in a patient with diabetes and nonresectable malignant insulinoma. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20110101 |
| Four-year follow-up of TYPHOON (trial to assess the use of the CYPHer sirolimus-eluting coronary stent in acute myocardial infarction treated with BallOON angioplasty). | JACC. Cardiovascular interventions 20110101 |
| Very late stent thrombosis after primary percutaneous coronary intervention with bare-metal and drug-eluting stents for ST-segment elevation myocardial infarction: a 15-year single-center experience. | JACC. Cardiovascular interventions 20110101 |
| Long-term follow-up of drug-eluting stents placed in the setting of ST-segment elevation myocardial infarction. | JACC. Cardiovascular interventions 20110101 |
| Persistent coronary no flow after wire insertion is an early and readily available mortality risk factor despite successful mechanical intervention in acute myocardial infarction: a pooled analysis from the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial | JACC. Cardiovascular interventions 20110101 |
| Prediction of 1-year clinical outcomes using the SYNTAX score in patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: a substudy of the STRATEGY (Single High-Dose Bolus Tirofiban and Sirolimus-Eluting Stent Versus Abciximab and Bare-Metal Stent in Acute Myocardial Infarction) and MULTISTRATEGY (Multicenter Evaluation of Single High-Dose Bolus Tirofiban Versus Abciximab With Sirolimus-Eluting Stent or Bare-Metal Stent in Acute Myocardial Infarc | JACC. Cardiovascular interventions 20110101 |
| Late restenosis following sirolimus-eluting stent implantation. | JACC. Cardiovascular interventions 20110101 |
| Retinoic acid and rapamycin differentially affect and synergistically promote the ex vivo expansion of natural human T regulatory cells. | PloS one 20110101 |
| The impact of sirolimus on hepatitis C recurrence after liver transplantation. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20110101 |
| Rapamycin blocks production of KSHV/HHV8: insights into the anti-tumor activity of an immunosuppressant drug. | PloS one 20110101 |
| Initial experience with temsirolimus in 2nd-, 3rd- and 4th-line therapy for metastatic renal cell cancer: good clinical response. | Urologia internationalis 20110101 |
| Perifosine and CCI 779 co-operate to induce cell death and decrease proliferation in PTEN-intact and PTEN-deficient PDGF-driven murine glioblastoma. | PloS one 20110101 |
| Clinical evidence on the use of anti-mTOR drugs in renal transplantation. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101 |
| Temsirolimus in metastatic chromophobe renal cell carcinoma after interferon and sorafenib therapy. | Anticancer research 20110101 |
| Response to mTOR inhibition: activity of eIF4E predicts sensitivity in cell lines and acquired changes in eIF4E regulation in breast cancer. | Molecular cancer 20110101 |
| The incidence of cancer and potential role of sirolimus immunosuppression conversion on mortality among a single-center renal transplantation cohort of 1,816 patients. | Transplantation proceedings 20110101 |
| Sirolimus prevents short-term renal changes induced by ischemia-reperfusion injury in rats. | American journal of nephrology 20110101 |
| Retrospective analyses of patient characteristics having predictive impact on survival under everolimus. | Onkologie 20110101 |
| Preclinical modeling of combined phosphatidylinositol-3-kinase inhibition with endocrine therapy for estrogen receptor-positive breast cancer. | Breast cancer research : BCR 20110101 |
| The clinical evaluation of the Endeavor zotarolimus-eluting coronary stent in Japanese patients with de novo native coronary artery lesions: primary results and 3-year follow-up of the Endeavor Japan study. | Cardiovascular revascularization medicine : including molecular interventions 20110101 |
| Late regression of Cypher in-stent restenosis. | Cardiovascular revascularization medicine : including molecular interventions 20110101 |
| [Immunosuppressive agents in kidney transplantation]. | Nihon Jinzo Gakkai shi 20110101 |
| [Autosomal dominant polycystic kidney disease]. | Nihon Jinzo Gakkai shi 20110101 |
| Efficacy of paclitaxel-eluting stent in patients with impaired glucose tolerance--comparison with sirolimus-eluting stent. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Candesartan with pioglitazone protects against endothelial dysfunction and inflammatory responses in porcine coronary arteries implanted with sirolimus-eluting stents. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Angioscopic assessment of arterial repair following biodegradable polymer-coated biolimus A9-eluting stent implantation. - Comparison with durable polymer-coated sirolimus-eluting stent-. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Rapamycin potentiates cytotoxicity by docetaxel possibly through downregulation of Survivin in lung cancer cells. | Journal of experimental & clinical cancer research : CR 20110101 |
| Human TSC2-null fibroblast-like cells induce hair follicle neogenesis and hamartoma morphogenesis. | Nature communications 20110101 |
| Inverse probability weighting to control for censoring in a post hoc analysis of quality-adjusted survival data from a clinical trial of temsirolimus for renal cell carcinoma. | Journal of medical economics 20110101 |
| Conversion from sirolimus to everolimus in kidney transplant recipients receiving a calcineurin-free regimen. | Clinical transplantation 20110101 |
| Targeting FK506 binding proteins to fight malarial and bacterial infections: current advances and future perspectives. | Current medicinal chemistry 20110101 |
| Combined therapeutic strategy to improve vascular endothelial function after implantation of sirolimus-eluting stents. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Protective role of autophagy in AGE-induced early injury of human vascular endothelial cells. | Molecular medicine reports 20110101 |
| Regression of Kaposi's sarcoma in a Sudanese kidney transplant recipient after conversion to sirolimus: a focus on a common clinical problem. | Arab journal of nephrology and transplantation 20110101 |
| The impact of new generation drug-eluting stent implantation on patients with chronic kidney disease and a single lesion in the proximal segment of the left anterior descending artery. | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20110101 |
| Tuberous sclerosis complex-1 deficiency attenuates diet-induced hepatic lipid accumulation. | PloS one 20110101 |
| Retrospective comparison of clinical and angiographic outcomes after sirolimus-eluting and bare-metal stent implantation in 312 consecutive, nonrandomized severely calcified lesions using a rotablator. | International heart journal 20110101 |
| Switching to sirolimus monotherapy for de novo tumors after liver transplantation. A preliminary experience. | Hepato-gastroenterology 20110101 |
| Amino acid signaling in TOR activation. | Annual review of biochemistry 20110101 |
| Host-based Th2 cell therapy for prolongation of cardiac allograft viability. | PloS one 20110101 |
| Rapid estimation of whole blood everolimus concentrations using architect sirolimus immunoassay and mathematical equations: comparison with everolimus values determined by liquid chromatography/mass spectrometry. | Journal of clinical laboratory analysis 20110101 |
| Rapamycin-loaded nanoparticles for inhibition of neointimal hyperplasia in experimental vein grafts. | Journal of cardiothoracic surgery 20110101 |
| Antigen-independent IFN-γ production by human naïve CD4 T cells activated by IL-12 plus IL-18. | PloS one 20110101 |
| Rapamycin-induced impaired wound healing is associated with compromised tissue lactate accumulation and extracellular matrix remodeling. | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20110101 |
| Sex difference in long-term clinical outcome after sirolimus-eluting stent implantation. | Coronary artery disease 20110101 |
| [Breast cancer therapy with combination of endocrine and target drugs]. | Voprosy onkologii 20110101 |
| Is sirolimus a therapeutic option for patients with progressive pulmonary lymphangioleiomyomatosis? | Respiratory research 20110101 |
| Immunosuppressant cytoprotection correlates with HMGB1 suppression in primary astrocyte cultures exposed to combined oxygen-glucose deprivation. | Pharmacological reports : PR 20110101 |
| Efficacy of temsirolimus after previous treatment with sunitinib, sorafenib or everolimus in advanced renal cell cancer. | Oncology 20110101 |
| Rapamycin ameliorates dystrophic phenotype in mdx mouse skeletal muscle. | Molecular medicine (Cambridge, Mass.) 20110101 |
| Characterization of the metabolic phenotype of rapamycin-treated CD8+ T cells with augmented ability to generate long-lasting memory cells. | PloS one 20110101 |
| Drug-eluting stent: importance of clinico-pathological correlations. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| [Changes of content of regulatory lymphocytes and concentration of soluble interleukine-2 receptor in blood of patients with ischemic heart disease after coronary artery angioplasty with implantation of stents with rapamycin covering]. | Kardiologiia 20110101 |
| Morphological and quantitative analysis of vascular wall and neointimal hyperplasia after coronary stenting: comparison of bare-metal and sirolimus-eluting stents using optical coherence tomography. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Origin of restenosis after drug-eluting stent implantation in hyperglycemia is inflammatory cells and thrombus. | Journal of atherosclerosis and thrombosis 20110101 |
| The role of mTOR inhibitors in renal diseases. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101 |
| Effects of rapamycin on angiomyolipomas in patients with tuberous sclerosis. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101 |
| Monitoring sirolimus levels: how does it affect the immunoassay used? | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20110101 |
| Revascularization of left main coronary artery disease. | Cardiology in review 20110101 |
| Estimating the threshold surface density of Gp120-CCR5 complexes necessary for HIV-1 envelope-mediated cell-cell fusion. | PloS one 20110101 |
| Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin signaling network in cancer stem cells. | Current medicinal chemistry 20110101 |
| Targeting mTOR signaling pathway in ovarian cancer. | Current medicinal chemistry 20110101 |
| Comparative study of clinical grade human tolerogenic dendritic cells. | Journal of translational medicine 20110101 |
| Sirolimus may be associated with early recurrence of biliary obstruction in liver transplant patients undergoing endoscopic stenting of biliary strictures. | Annals of hepatology 20110101 |
| Effects of cyclosporine, tacrolimus and rapamycin on renal calcium transport and vitamin D metabolism. | American journal of nephrology 20110101 |
| The combination of RAD001 and NVP-BEZ235 exerts synergistic anticancer activity against non-small cell lung cancer in vitro and in vivo. | PloS one 20110101 |
| Mammalian target of rapamycin is a therapeutic target for murine ovarian endometrioid adenocarcinomas with dysregulated Wnt/β-catenin and PTEN. | PloS one 20110101 |
| Rapamycin-based inducible translocation systems for studying phagocytosis. | Methods in molecular biology (Clifton, N.J.) 20110101 |
| Calcineurin inhibitor-based and free regimens have distinct gene expression patterns in subclinical graft fibrosis. | Annals of transplantation 20110101 |
| Collapsing glomerulopathy in a renal transplant recipient: potential molecular mechanisms. | Annals of transplantation 20110101 |
| [Rapamycin effect on senescence and autophagy processes in human cell lines]. | Medicina 20110101 |
| mTOR controls ovarian follicle growth by regulating granulosa cell proliferation. | PloS one 20110101 |
| Determination of blood everolimus concentrations in kidney and liver transplant recipients using the sirolimus antibody conjugated magnetic immunoassay (ACMIA). | Clinical laboratory 20110101 |
| Comparison of paclitaxel-, sirolimus-, and zotarolimus-eluting stents in patients with acute ST-segment elevation myocardial infarction and metabolic syndrome. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Impact of acute gain on clinical outcomes of patients treated with sirolimus-eluting stent. - A sub-analysis study from the STLLR trial-. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Very late sirolimus-eluting stent thrombosis due to stent fracture and late-acquired incomplete stent apposition detected on multislice computed tomography. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| Direct microscopic observation of striations in a fractured section of a sirolimus-eluting stent (Cypher Bx Velocity®) indicates induction of stent fracture by continuous shear stress. | International heart journal 20110101 |
| Rapamycin inhibits the proliferation and apoptosis of gastric cancer cells by down regulating the expression of survivin. | Hepato-gastroenterology 20110101 |
| Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer. | Journal of translational medicine 20110101 |
| A periadventitial sirolimus-releasing mesh decreased intimal hyperplasia in a rabbit model. | Physiological research 20110101 |
| Involvement of mTOR signaling in sphingosylphosphorylcholine-induced hypopigmentation effects. | Journal of biomedical science 20110101 |
| Evolution of glomerular filtration rate, renal injury markers, anemia, and angiotensin blockers use after change from calcineurin inhibitors to sirolimus in transplant patients with neoplasia versus chronic allograft nephropathy. | Transplantation proceedings 20110101 |
| Everolimus in clinical practice in long-term liver transplantation: an observational study. | Transplantation proceedings 20110101 |
| Effectiveness and safety of everolimus in the treatment of autoimmune hepatitis related to anti-hepatitis C virus therapy after liver transplant: three case reports. | Transplantation proceedings 20110101 |
| Conversion to everolimus in liver transplant patients with renal dysfunction. | Transplantation proceedings 20110101 |
| Long-term use of everolimus in lung transplant patients. | Transplantation proceedings 20110101 |
| Cutaneous and mucosal aphthosis during temsirolimus therapy for advanced renal cell carcinoma: review of cutaneous and mucosal side effects of mTOR inhibitors. | Dermatology (Basel, Switzerland) 20110101 |
| SB202190-induced cell type-specific vacuole formation and defective autophagy do not depend on p38 MAP kinase inhibition. | PloS one 20110101 |
| Endothelial-like cells in chronic thromboembolic pulmonary hypertension: crosstalk with myofibroblast-like cells. | Respiratory research 20110101 |
| Molecular targeting of prostate cancer cells by a triple drug combination down-regulates integrin driven adhesion processes, delays cell cycle progression and interferes with the cdk-cyclin axis. | BMC cancer 20110101 |
| [Mass spectrometry-based quantitative analysis and biomarker discovery]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110101 |
| Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1. | PloS one 20110101 |
| Calcineurin inhibitor-induced and Ras-mediated overexpression of VEGF in renal cancer cells involves mTOR through the regulation of PRAS40. | PloS one 20110101 |
| The peptidyl prolyl isomerase Rrd1 regulates the elongation of RNA polymerase II during transcriptional stresses. | PloS one 20110101 |
| Inhibition of radiation induced migration of human head and neck squamous cell carcinoma cells by blocking of EGF receptor pathways. | BMC cancer 20110101 |
| c-Myc dependent expression of pro-apoptotic Bim renders HER2-overexpressing breast cancer cells dependent on anti-apoptotic Mcl-1. | Molecular cancer 20110101 |
| Chikungunya triggers an autophagic process which promotes viral replication. | Virology journal 20110101 |
| Molecular mechanisms of l-DOPA-induced dyskinesia. | International review of neurobiology 20110101 |
| Economic evaluation of everolimus versus sorafenib for the treatment of metastatic renal cell carcinoma after failure of first-line sunitinib. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20110101 |
| Multicenter phase 2 trial of sirolimus for tuberous sclerosis: kidney angiomyolipomas and other tumors regress and VEGF- D levels decrease. | PloS one 20110101 |
| Involvement of mTOR in CXCL12 mediated T cell signaling and migration. | PloS one 20110101 |
| The activation of the p53 pathway by the AMP mimetic AICAR is reduced by inhibitors of the ATM or mTOR kinases. | Mechanisms of ageing and development 20110101 |
| Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells. | PloS one 20110101 |
| The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation. | Molecular systems biology 20110101 |
| Ezetimibe in sirolimus-associated hyperlipidemia: to add or not to add to statins? | Annals of transplantation 20110101 |
| The combination of gefitinib and RAD001 inhibits growth of HER2 overexpressing breast cancer cells and tumors irrespective of trastuzumab sensitivity. | BMC cancer 20110101 |
| Temporal regulation of rapamycin on memory CTL programming by IL-12. | PloS one 20110101 |
| Anti-proliferation effects of Sirolimus sustained delivery film in rabbit glaucoma filtration surgery. | Molecular vision 20110101 |
| Inducing autophagy by rapamycin before, but not after, the formation of plaques and tangles ameliorates cognitive deficits. | PloS one 20110101 |
| Human glial-restricted progenitor transplantation into cervical spinal cord of the SOD1 mouse model of ALS. | PloS one 20110101 |
| Elimination of proliferating cells unmasks the shift from senescence to quiescence caused by rapamycin. | PloS one 20110101 |
| A mechanism for synergy with combined mTOR and PI3 kinase inhibitors. | PloS one 20110101 |
| Retrospective comparison of the clinical and angiographic outcomes of the sirolimus-eluting stent and the bare-metal stent in 2031 nonrandomized consecutive de novo native coronary lesions. | Internal medicine (Tokyo, Japan) 20110101 |
| Neoadjuvant chemotherapy and targeted therapies: a promising strategy. | Journal of the National Cancer Institute. Monographs 20110101 |
| Combined treatment with antioxidants and immunosuppressants on cytokine release by human peripheral blood mononuclear cells - chemically injured keratocyte reaction. | Molecular vision 20110101 |
| Mapping the interaction of Snf1 with TORC1 in Saccharomyces cerevisiae. | Molecular systems biology 20110101 |
| [Metastatic renal cell carcinoma treated with everolimus--data from the RENIS Clinical Registry]. | Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20110101 |
| Targeting notch pathway enhances rapamycin antitumor activity in pancreas cancers through PTEN phosphorylation. | Molecular cancer 20110101 |
| Concurrent HDAC and mTORC1 inhibition attenuate androgen receptor and hypoxia signaling associated with alterations in microRNA expression. | PloS one 20110101 |
| Everolimus and long acting octreotide as a volume reducing treatment of polycystic livers (ELATE): study protocol for a randomized controlled trial. | Trials 20110101 |
| S6K1 and 4E-BP1 are independent regulated and control cellular growth in bladder cancer. | PloS one 20110101 |
| Giant bilateral renal angiomyolipomas and lymphangioleiomyomatosis presenting after two successive pregnancies successfully treated with surgery and rapamycin. | TheScientificWorldJournal 20110101 |
| Phase I-II study of everolimus and low-dose oral cyclophosphamide in patients with metastatic renal cell cancer. | BMC cancer 20110101 |
| Evaluation of an AAV2-based rapamycin-regulated glial cell line-derived neurotrophic factor (GDNF) expression vector system. | PloS one 20110101 |
| Peroxisome proliferator-activated receptor-gamma agonists suppress tissue factor overexpression in rat balloon injury model with paclitaxel infusion. | PloS one 20110101 |
| Transient mTOR inhibition facilitates continuous growth of liver tumors by modulating the maintenance of CD133+ cell populations. | PloS one 20110101 |
| Therapy for aplastic anemia. | Hematology. American Society of Hematology. Education Program 20110101 |
| Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process. | International journal of nanomedicine 20110101 |
| Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation. | PloS one 20110101 |
| Two cases of everolimus-associated interstitial pneumonia in patients with renal cell carcinoma. | Internal medicine (Tokyo, Japan) 20110101 |
| Reversing melanoma cross-resistance to BRAF and MEK inhibitors by co-targeting the AKT/mTOR pathway. | PloS one 20110101 |
| Progressive lymphangiomatosis and Gorham's disease: case report and clinical implications. | Lymphatic research and biology 20110101 |
| Pulmonary embolism and reactivation of tuberculosis during everolimus therapy in a kidney transplant recipient. | Annals of transplantation 20110101 |
| Sensitivity of global translation to mTOR inhibition in REN cells depends on the equilibrium between eIF4E and 4E-BP1. | PloS one 20110101 |
| Rapamycin prevents endothelial cell migration by inhibiting the endothelial-to-mesenchymal transition and matrix metalloproteinase-2 and -9: an in vitro study. | Molecular vision 20110101 |
| Procedure for determination of immunosuppressive drugs in whole blood with liquid chromatography-isotope dilution mass spectrometry. | Clinical laboratory 20110101 |
| Resveratrol inhibits protein translation in hepatic cells. | PloS one 20110101 |
| Compassionate use of everolimus in a patient with a neuroendocrine tumor: a case report and discussion of the literature. | Oncology research 20110101 |
| Combination effects of paclitaxel with signaling inhibitors in endometrial cancer cells. | Asian Pacific journal of cancer prevention : APJCP 20110101 |
| [Efficiency of medical versus endovascular treatment using drug-eluting stents in coronary heart disease patients with extensive lesion of the coronary bed]. | Vestnik rentgenologii i radiologii 20110101 |
| [Post transplant lymphoproliferative disorder (PTLD)--10 years follow-up]. | Przeglad lekarski 20110101 |
| Acute thrombosis of drug eluting stent following protamine: a case report. | Indian heart journal 20110101 |
| Two-year outcomes in thoracic transplant recipients after conversion to everolimus with reduced calcineurin inhibitor within a multicenter, open-label, randomized trial. | Transplantation 20101227 |
| The International Registry on Hand and Composite Tissue Transplantation. | Transplantation 20101227 |
| Anti-BK virus mechanisms of sirolimus and leflunomide alone and in combination: toward a new therapy for BK virus infection. | Transplantation 20101227 |
| Hsp90 and environmental stress transform the adaptive value of natural genetic variation. | Science (New York, N.Y.) 20101224 |
| Chemical genomic screening reveals synergism between parthenolide and inhibitors of the PI-3 kinase and mTOR pathways. | Blood 20101223 |
| RAD001 shows activity against gastric cancer cells and overcomes 5-FU resistance by downregulating thymidylate synthase. | Cancer letters 20101218 |
| Development of a dot-blot assay for screening monoclonal antibodies to low-molecular-mass drugs. | Analytical biochemistry 20101215 |
| Treatment of childhood kaposiform hemangioendothelioma with sirolimus. | Pediatric blood & cancer 20101215 |
| Temsirolimus for metastatic desmoplastic small round cell tumor. | Pediatric blood & cancer 20101215 |
| Immunosuppression involving soluble CD83 induces tolerogenic dendritic cells that prevent cardiac allograft rejection. | Transplantation 20101215 |
| Prolidase-dependent regulation of TGF β (corrected) and TGF β receptor expressions in human skin fibroblasts. | European journal of pharmacology 20101215 |
| Unequal in the absence of death: a novel screen identifies cytotoxic compounds selective for cells with activated Akt. | Cancer biology & therapy 20101215 |
| Identification of Akt-selective cytotoxic compounds that enhance cytotoxic responses to rapamycin. | Cancer biology & therapy 20101215 |
| Zoledronic acid potentiates mTOR inhibition and abolishes the resistance of osteosarcoma cells to RAD001 (Everolimus): pivotal role of the prenylation process. | Cancer research 20101215 |
| Isolation and expansion of human natural T regulatory cells for cellular therapy. | Journal of immunological methods 20101215 |
| Mammalian target of rapamycin: biological function and target for novel anticancer agents. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20101215 |
| Increasing healthy lifespan by suppressing aging in our lifetime: preliminary proposal. | Cell cycle (Georgetown, Tex.) 20101215 |
| Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas. | Cancer research 20101215 |
| BRAF mutation-selective inhibition of thyroid cancer cells by the novel MEK inhibitor RDEA119 and genetic-potentiated synergism with the mTOR inhibitor temsirolimus. | International journal of cancer 20101215 |
| Outcomes in diabetic and nondiabetic patients treated with everolimus- or paclitaxel-eluting stents: results from the SPIRIT IV clinical trial (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System). | Journal of the American College of Cardiology 20101214 |
| An oscillatory switch in mTOR kinase activity sets regulatory T cell responsiveness. | Immunity 20101214 |
| C60(Nd) nanoparticles enhance chemotherapeutic susceptibility of cancer cells by modulation of autophagy. | Nanotechnology 20101210 |
| GVHD after haploidentical transplantation: a novel, MHC-defined rhesus macaque model identifies CD28- CD8+ T cells as a reservoir of breakthrough T-cell proliferation during costimulation blockade and sirolimus-based immunosuppression. | Blood 20101209 |
| Drug-eluting versus bare-metal stents in large coronary arteries. | The New England journal of medicine 20101209 |
| Combinations of mTORC1 inhibitor RAD001 with gemcitabine and paclitaxel for treating non-Hodgkin lymphoma. | Cancer letters 20101208 |
| Copper-doxorubicin as a nanoparticle cargo retains efficacy with minimal toxicity. | Molecular pharmaceutics 20101206 |
| Targeted drug delivery to lymphocytes: a route to site-specific immunomodulation? | Molecular pharmaceutics 20101206 |
| Rapamycin inhibits cytoskeleton reorganization and cell motility by suppressing RhoA expression and activity. | The Journal of biological chemistry 20101203 |
| Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells. | Nature 20101202 |
| Reflex sympathetic dystrophy in patients with metastatic renal cell carcinoma treated with everolimus. | Investigational new drugs 20101201 |
| TAE226-mediated inhibition of focal adhesion kinase interferes with tumor angiogenesis and vasculogenesis. | Investigational new drugs 20101201 |
| Pharmacodynamic evaluation of temsirolimus in patients with newly diagnosed advanced-stage head and neck squamous cell carcinoma. | Head & neck 20101201 |
| Mammalian target of rapamycin signaling in the spinal cord is required for neuronal plasticity and behavioral hypersensitivity associated with neuropathy in the rat. | The journal of pain : official journal of the American Pain Society 20101201 |
| Intrinsic and extrinsic mechanisms of oocyte loss. | Molecular human reproduction 20101201 |
| Quantitative determination of sirolimus in dog blood using liquid chromatography-tandem mass spectrometry, and its applications to pharmacokinetic studies. | Journal of pharmaceutical and biomedical analysis 20101201 |
| A phase 2 study of the oral mammalian target of rapamycin inhibitor, everolimus, in patients with recurrent endometrial carcinoma. | Cancer 20101201 |
| TORC1 kinase and the S-phase cyclin Clb5 collaborate to promote mitotic spindle assembly and DNA replication in S. cerevisiae. | Current genetics 20101201 |
| Sirolimus for calcineurin inhibitors in organ transplantation: contra. | Kidney international 20101201 |
| Dysregulation of epithelial Na+ absorption induced by inhibition of the kinases TORC1 and TORC2. | British journal of pharmacology 20101201 |
| Autosomal dominant polycystic kidney disease and mTOR inhibitors: the narrow road between hope and disappointment. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101201 |
| Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes. | Endocrine-related cancer 20101201 |
| Regulation of gastric hormones by systemic rapamycin. | Peptides 20101201 |
| Comparison of three-year clinical outcomes between sirolimus-versus paclitaxel-eluting stents in diabetic patients: prospective randomized multicenter trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201 |
| Mammalian target of rapamycin signaling activation patterns in neuroendocrine tumors of the lung. | Endocrine-related cancer 20101201 |
| Silymarin inhibits endothelial progenitor cells' senescence and protects against the antiproliferative activity of rapamycin: preliminary study. | Journal of cardiovascular pharmacology 20101201 |
| Curcumin inhibits carcinogen and nicotine-induced Mammalian target of rapamycin pathway activation in head and neck squamous cell carcinoma. | Cancer prevention research (Philadelphia, Pa.) 20101201 |
| mTOR inhibitor rapamycin suppresses striatal post-ischemic LTP. | Experimental neurology 20101201 |
| Crush stenting with drug-eluting stents: relevance of coronary bifurcation lesion location on angiographic and clinical outcomes. | Clinical cardiology 20101201 |
| Dual blocking of mTor and PI3K elicits a prodifferentiation effect on glioblastoma stem-like cells. | Neuro-oncology 20101201 |
| The potential benefits of rapamycin on renal function, tolerance, fibrosis, and malignancy following transplantation. | Kidney international 20101201 |
| Rapamycin inhibits cell proliferation in type I and type II endometrial carcinomas: a search for biomarkers of sensitivity to treatment. | Gynecologic oncology 20101201 |
| Third-line sorafenib after sequential therapy with sunitinib and mTOR inhibitors in metastatic renal cell carcinoma. | European urology 20101201 |
| Inhibition of voltage-gated K+ channels in dendritic cells by rapamycin. | American journal of physiology. Cell physiology 20101201 |
| mTOR-inhibition in metastatic renal cell carcinoma. Focus on temsirolimus: a review. | Minerva urologica e nefrologica = The Italian journal of urology and nephrology 20101201 |
| Mechanical stretch activates signaling events for protein translation initiation and elongation in C2C12 myoblasts. | Molecules and cells 20101201 |
| Phase I study of everolimus plus weekly paclitaxel and trastuzumab in patients with metastatic breast cancer pretreated with trastuzumab. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101201 |
| Cellular and molecular changes associated with inhibitory effect of pioglitazone on neointimal growth in patients with type 2 diabetes after zotarolimus-eluting stent implantation. | Arteriosclerosis, thrombosis, and vascular biology 20101201 |
| Determination of cyclosporine, tacrolimus, sirolimus and everolimus by liquid chromatography coupled to electrospray ionization and tandem mass spectrometry: assessment of matrix effects and assay performance. | Scandinavian journal of clinical and laboratory investigation 20101201 |
| mTORC1 inhibition via rapamycin promotes triacylglycerol lipolysis and release of free fatty acids in 3T3-L1 adipocytes. | Lipids 20101201 |
| Phase II study of everolimus (RAD001) in previously treated small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101201 |
| Six-month results of the NEVO Res-Elution I (NEVO RES-I) trial: a randomized, multicenter comparison of the NEVO sirolimus-eluting coronary stent with the TAXUS Liberté paclitaxel-eluting stent in de novo native coronary artery lesions. | Circulation. Cardiovascular interventions 20101201 |
| Lysosomal accumulation of mTOR is enhanced by rapamycin. | Histochemistry and cell biology 20101201 |
| Developmental pharmacogenetics of immunosuppressants in pediatric organ transplantation. | Therapeutic drug monitoring 20101201 |
| Development of a validated high-throughput LC-ESI-MS method for determination of sirolimus on dried blood spots. | Biomedical chromatography : BMC 20101201 |
| Protein kinase Mzeta is essential for the induction and maintenance of dopamine-induced long-term potentiation in apical CA1 dendrites. | Learning & memory (Cold Spring Harbor, N.Y.) 20101201 |
| The Kounis syndrome in everolimus-eluting stents and paclitaxel-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201 |
| Safety and efficacy of sirolimus-eluting stent implantation in patients with acute coronary syndrome in the real world. | The American journal of cardiology 20101201 |
| Effect of FKBP65, a putative elastin chaperone, on the coacervation of tropoelastin in vitro. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20101201 |
| High glycemic stenting menu. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101201 |
| Do mTOR inhibitors still have a future in ADPKD? | Nature reviews. Nephrology 20101201 |
| Sirolimus and kidney transplantation: unraveling an inflammatory affair. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101201 |
| Comparative transcriptional and phenotypic peripheral blood analysis of kidney recipients under cyclosporin A or sirolimus monotherapy. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101201 |
| Recurrent stent fracture: first reported image of everolimus-eluting stent fracture leading to recurrent restenosis in cardiac allograft vasculopathy. | The Journal of invasive cardiology 20101201 |
| Proteinuria among primarily sirolimus treated live-donor renal transplant recipients' long-term experience. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20101201 |
| Rapamycin inhibits anal carcinogenesis in two preclinical animal models. | Cancer prevention research (Philadelphia, Pa.) 20101201 |
| mTOR and its link to the picture of Dorian Gray - re-activation of mTOR promotes aging. | Aging 20101201 |
| Intracellular amino acid sensing and mTORC1-regulated growth: new ways to block an old target? | Current opinion in investigational drugs (London, England : 2000) 20101201 |
| Long-term outcome of very early cyclosporine minimization and de novo everolimus therapy in kidney transplant recipients: a pharmacokinetic guided approach. | Transplantation proceedings 20101201 |
| Conversion from calcineurin inhibitor to either mycophenolate mofetil or sirolimus improves renal function in liver transplant recipients with chronic kidney disease: results of a prospective randomized trial. | Transplantation proceedings 20101201 |
| Individualizing early use of sirolimus in renal transplantation. | Transplantation proceedings 20101201 |
| Potential use of rapamycin in HIV infection. | British journal of clinical pharmacology 20101201 |
| Unilateral upper limb lympatic obstruction and severe lymphoedema in a patient on long-term sirolimus. | Nephrology (Carlton, Vic.) 20101201 |
| [Effect of rapamycin on proliferation of acute myeloid leukemia cell lines HL-60 and HL-60/VCR]. | Zhongguo shi yan xue ye xue za zhi 20101201 |
| [mTOR, the mammalian target of rapamycin]. | Medecine sciences : M/S 20101201 |
| More than 4 years of progression-free survival in a patient with metastatic renal cell carcinoma treated sequentially with sunitinib, everolimus, sorafenib, and temsirolimus. | Anticancer research 20101201 |
| DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence. | Aging 20101201 |
| [A case report of very late thrombosis in two sirolimus-eluting stents]. | Zhonghua xin xue guan bing za zhi 20101201 |
| [Down-regulation of mTOR activity and survivin expression during tamoxifen-induced apoptosis in hepatoblastoma cells]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20101201 |
| Clinical follow-up 3 years after everolimus- and paclitaxel-eluting stents: a pooled analysis from the SPIRIT II (A Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Patients With De Novo Native Coronary Artery Lesions) and SPIRIT III (A Clinical Evaluation of the Investigational Device XIENCE V Everolimus Eluting Coronary Stent System [EECSS] in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) randomized trials. | JACC. Cardiovascular interventions 20101201 |
| Comparison of everolimus-eluting and paclitaxel-eluting coronary stents in patients undergoing multilesion and multivessel intervention: the SPIRIT III (A Clinical Evaluation of the Investigational Device XIENCE V Everolimus Eluting Coronary Stent System [EECSS] in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) and SPIRIT IV (Clinical Evaluation of the XIENCE V Everolimus Eluting Coronary Stent System in the Treatment of Subjects With De Novo Native Coronary Artery Lesions) randomize | JACC. Cardiovascular interventions 20101201 |
| Long-term clinical outcomes with zotarolimus-eluting versus bare-metal coronary stents. | JACC. Cardiovascular interventions 20101201 |
| Temsirolimus and mantle cell lymphoma. Highly toxic, limited efficacy. | Prescrire international 20101201 |
| High entrapment efficiency of chitosan/polylactic acid/tripolyphotspate nanosized microcapsules for rapamycin by an emulsion-evaporation approach. | Journal of biomedical nanotechnology 20101201 |
| The AXXESS™ self-expanding biolimus A9™ eluting stent system for coronary bifurcation lesions. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201 |
| Dedicated everolimus-eluting side branch access system: XIENCE SBA. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201 |
| Side branch occlusion with everolimus-eluting and paclitaxel-eluting stents: three-year results from the SPIRIT III randomised trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101201 |
| Intracoronary optical coherence tomography and histology at 1 month and 2, 3, and 4 years after implantation of everolimus-eluting bioresorbable vascular scaffolds in a porcine coronary artery model: an attempt to decipher the human optical coherence tomography images in the ABSORB trial. | Circulation 20101130 |
| Evaluation of the second generation of a bioresorbable everolimus drug-eluting vascular scaffold for treatment of de novo coronary artery stenosis: six-month clinical and imaging outcomes. | Circulation 20101130 |
| Activation of phosphatidylinositol 3-kinase/Akt-mammalian target of Rapamycin signaling pathway in the hippocampus is essential for the acquisition of morphine-induced place preference in rats. | Neuroscience 20101124 |
| Sirolimus plus sorafenib in treating HCC recurrence after liver transplantation: a case report. | World journal of gastroenterology 20101121 |
| Bevacizumab and everolimus in renal cancer: a rational way forward. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101120 |
| Sirolimus- vs. paclitaxel-eluting stents in patients undergoing off-label percutaneous coronary intervention. | International journal of cardiology 20101119 |
| Multiple cellular proteins modulate the dynamics of K-ras association with the plasma membrane. | Biophysical journal 20101117 |
| Roles of autophagy in cetuximab-mediated cancer therapy against EGFR. | Autophagy 20101116 |
| B55β-associated PP2A complex controls PDK1-directed myc signaling and modulates rapamycin sensitivity in colorectal cancer. | Cancer cell 20101116 |
| A collection of caged compounds for probing roles of local translation in neurobiology. | Bioorganic & medicinal chemistry 20101115 |
| Sex-specific outcomes following revascularization with zotarolimus-eluting stents: comparison of angiographic and late-term clinical results. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101115 |
| Combination of temsirolimus (CCI-779) with chemoradiation in newly diagnosed glioblastoma multiforme (GBM) (NCCTG trial N027D) is associated with increased infectious risks. | Clinical cancer research : an official journal of the American Association for Cancer Research 20101115 |
| Comparison of five-year outcome of octogenarians undergoing percutaneous coronary intervention with drug-eluting versus bare-metal stents (from the RESEARCH and T-SEARCH Registries). | The American journal of cardiology 20101115 |
| Impact of moderate renal insufficiency on restenosis and adverse clinical events after sirolimus-eluting and bare metal stent implantation (from the SIRIUS trials). | The American journal of cardiology 20101115 |
| Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of Apc and Pten in the mouse salivary gland: implications for human acinic cell carcinoma. | Cancer research 20101115 |
| Gender medicine and drug eluting coronary stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101115 |
| A stress-responsive system for mitochondrial protein degradation. | Molecular cell 20101112 |
| Akt and autophagy cooperate to promote survival of drug-resistant glioma. | Science signaling 20101109 |
| Sirolimus-eluting versus bare-metal stent implantation in patients with ostial lesions. | International journal of cardiology 20101105 |
| Everolimus for subependymal giant-cell astrocytomas in tuberous sclerosis. | The New England journal of medicine 20101104 |
| Precise control of protein concentration in living cells. | Angewandte Chemie (International ed. in English) 20101102 |
| Inducible somatic oocyte destruction in response to rapamycin requires wild-type regulation of follicle cell epithelial polarity. | Cell death and differentiation 20101101 |
| Cyclin D1 and cyclin D3 show divergent responses to distinct mitogenic stimulation. | Journal of cellular physiology 20101101 |
| Evidence for cell cycle-dependent, rapamycin-resistant phosphorylation of ribosomal protein S6 at S240/244. | Amino acids 20101101 |
| Bortezomib and sirolimus inhibit the chronic active antibody-mediated rejection in experimental renal transplantation in the rat. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101 |
| Supplementing L-leucine to a low-protein diet increases tissue protein synthesis in weanling pigs. | Amino acids 20101101 |
| Efficacy and safety of de novo or early everolimus with low cyclosporine in deceased-donor kidney transplant recipients at specified risk of delayed graft function: 12-month results of a randomized, multicenter trial. | Transplant international : official journal of the European Society for Organ Transplantation 20101101 |
| Evaluation of the effects of everolimus-eluting and paclitaxel-eluting stents on target lesions with jailed side branches: 2-year results from the SPIRIT III randomized trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101 |
| Comparative effects of sirolimus and cyclosporin on conduit arteries endothelial function in kidney recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20101101 |
| Posttranslational regulation of membrane type 1-matrix metalloproteinase (MT1-MMP) in mouse PTEN null prostate cancer cells: Enhanced surface expression and differential O-glycosylation of MT1-MMP. | Biochimica et biophysica acta 20101101 |
| Low-dose rapamycin reduces kidney volume angiomyolipomas and prevents the loss of renal function in a patient with tuberous sclerosis complex. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101 |
| Efficacy of everolimus eluting stent implantation in patients with calcified coronary culprit lesions: two-year angiographic and three-year clinical results from the SPIRIT II study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101 |
| Maintenance immunosuppressive therapy with everolimus preserves humoral immune responses. | Kidney international 20101101 |
| Sirolimus immunosuppression for graft-versus-host disease prophylaxis and therapy: an update. | Current opinion in hematology 20101101 |
| Usefulness of sirolimus-based immunosuppression in ameliorating pre-transplant renal dysfunction in patients with Chagas' heart disease. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20101101 |
| Concurrent involved field radiation therapy and temsirolimus in refractory mantle cell lymphoma (MCL). | American journal of hematology 20101101 |
| Efficacy and safety/toxicity study of recombinant vaccinia virus JX-594 in two immunocompetent animal models of glioma. | Molecular therapy : the journal of the American Society of Gene Therapy 20101101 |
| Lipids and renal cystic disease. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20101101 |
| Childhood rhabdomyosarcoma: new insight on biology and treatment. | Current oncology reports 20101101 |
| Maintenance and consolidation strategies in non-Hodgkin's lymphoma: A review of the data. | Current oncology reports 20101101 |
| Increased levels of p70S6 phosphorylation in the G93A mouse model of Amyotrophic Lateral Sclerosis and in valine-exposed cortical neurons in culture. | Experimental neurology 20101101 |
| Temsirolimus has activity in non-mantle cell non-Hodgkin's lymphoma subtypes: The University of Chicago phase II consortium. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101101 |
| An MHC-defined primate model reveals significant rejection of bone marrow after mixed chimerism induction despite full MHC matching. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101101 |
| Antitumor effect of temsirolimus against oral squamous cell carcinoma associated with bone destruction. | Molecular cancer therapeutics 20101101 |
| Comparisons of the effects of stent eccentricity on the neointimal hyperplasia between sirolimus-eluting stent versus paclitaxel-eluting stent. | Yonsei medical journal 20101101 |
| Repeated sirolimus-eluting stent implantation to treat sirolimus-eluting stent and bare-metal stent restenosis. | Circulation journal : official journal of the Japanese Circulation Society 20101101 |
| Comparison of vascular response to zotarolimus-eluting stent vs paclitaxel-eluting stent implantation: pooled IVUS results from the ZoMaxx I and II trials. | Circulation journal : official journal of the Japanese Circulation Society 20101101 |
| Distinct patterns of autophagy evoked by two benzoxazine derivatives in vascular endothelial cells. | Autophagy 20101101 |
| STAT3 transcriptional factor activated by reactive oxygen species induces IL6 in starvation-induced autophagy of cancer cells. | Autophagy 20101101 |
| Inhibition of the mammalian target of rapamycin promotes cyclic AMP-induced differentiation of NG108-15 cells. | Autophagy 20101101 |
| Three-month dual antiplatelet therapy after implantation of zotarolimus-eluting stents: the DATE (Duration of Dual Antiplatelet Therapy AfterImplantation of Endeavor Stent) registry. | Circulation journal : official journal of the Japanese Circulation Society 20101101 |
| The use of sirolimus as a rescue therapy in pediatric intestinal transplant recipients. | Pediatric transplantation 20101101 |
| Activation of Atg1 kinase in autophagy by regulated phosphorylation. | Autophagy 20101101 |
| Autophagy: a target for retinoic acids. | Autophagy 20101101 |
| Bevacizumab for metastatic renal cell carcinoma: a monoclonal antibody in a sea of small molecules. | Expert opinion on biological therapy 20101101 |
| Pharmacologic eigenvalues: beating the rap on bone marrow failure. | The Journal of clinical investigation 20101101 |
| Phase I study of the oral mammalian target of rapamycin inhibitor everolimus (RAD001) in Japanese patients with relapsed or refractory non-Hodgkin lymphoma. | International journal of hematology 20101101 |
| Warning: this report does not address heavily calcified coronary arteries. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101 |
| More openness and a little less strut: two good ideas for stents and the people who implant them. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20101101 |
| Mammalian target of rapamycin complex 1 is involved in differentiation of regenerating myofibers in vivo. | Muscle & nerve 20101101 |
| Transplantation: can sirolimus prevent skin cancer in transplant recipients? | Nature reviews. Nephrology 20101101 |
| Comparison of outcomes in patients with insulin-dependent versus non-insulin dependent diabetes mellitus receiving drug-eluting stents (from the first phase of the prospective multicenter German DES.DE registry). | The American journal of cardiology 20101101 |
| Lack of effect of oral beta-blocker therapy at discharge on long-term clinical outcomes of ST-segment elevation acute myocardial infarction after primary percutaneous coronary intervention. | The American journal of cardiology 20101101 |
| Could Paclitaxel-eluting stents be superior to sirolimus-eluting stents for the treatment of saphenous vein graft lesions? | The American journal of cardiology 20101101 |
| Conditionally controlling nuclear trafficking in yeast by chemical-induced protein dimerization. | Nature protocols 20101101 |
| Differing effects of systemically administered rapamycin on consolidation and reconsolidation of context vs. cued fear memories. | Learning & memory (Cold Spring Harbor, N.Y.) 20101101 |
| Impact of insulin-treated diabetes and hemodialysis on long-term clinical outcomes following sirolimus-eluting stent deployment. Insights from a sub-study of the Cypher Stent Japan Post-Marketing Surveillance(Cypher J-PMS) Registry. | Circulation journal : official journal of the Japanese Circulation Society 20101101 |
| Long-term follow-up of the randomised controlled trial to evaluate the safety and efficacy of the zotarolimus-eluting driver coronary stent in de novo native coronary artery lesions: five year outcomes in the ENDEAVOR II study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101101 |
| Strut tissue coverage and endothelial cell coverage: a comparison between bare metal stent platforms and platinum chromium stents with and without everolimus-eluting coating. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20101101 |
| A phase I dose-escalation study to evaluate safety and tolerability of sorafenib combined with sirolimus in patients with advanced solid cancer. | British journal of cancer 20101101 |
| The effect of shear stress on neointimal response following sirolimus- and paclitaxel-eluting stent implantation compared with bare-metal stents in humans. | JACC. Cardiovascular interventions 20101101 |
| A comparison of the conformability of everolimus-eluting bioresorbable vascular scaffolds to metal platform coronary stents. | JACC. Cardiovascular interventions 20101101 |
| In vivo assessment of local intravascular hemodynamics and arterial morphology to investigate vascular outcomes: a growing field coming of age. | JACC. Cardiovascular interventions 20101101 |
| Neovascular microchannels in sirolimus-eluting stent occlusion at late phase. | JACC. Cardiovascular interventions 20101101 |
| Low-dose calcineurin inhibitor regimen combined with mammalian target of rapamycin inhibitors preserves kidney functions in renal transplant recipients without allograft nephropathy. | Transplantation proceedings 20101101 |
| Malignancies after heart transplantation: incidence, risk factors, and effects of calcineurin inhibitor withdrawal. | Transplantation proceedings 20101101 |
| Common occurrence of everolimus-associated aphthous stomatitis in Japanese heart transplant recipients. | Transplantation proceedings 20101101 |
| Use of genetically modified allograft to deliver local immunomodulatory molecule with minimal systemic toxicity in a rat model of allogeneic skin flap transplantation. | Transplantation proceedings 20101101 |
| Recurrent non-melanoma skin cancer: remission of field cancerization after conversion from calcineurin inhibitor- to proliferation signal inhibitor-based immunosuppression in a cardiac transplant recipient. | Transplantation proceedings 20101101 |
| Immunoregulation and tolerance. | Transplantation proceedings 20101101 |
| Can we eliminate both calcineurin inhibitors and steroids? | Transplantation proceedings 20101101 |
| Rationale for using belatacept in combination with sirolimus. | Transplantation proceedings 20101101 |
| Can immunosuppressive strategies be used to reduce cancer risk in renal transplant patients? | Transplantation proceedings 20101101 |
| Clinical insights for cancer outcomes in renal transplant patients. | Transplantation proceedings 20101101 |
| Regression of left ventricular hypertrophy in kidney transplant recipients: the potential role for inhibition of mammalian target of rapamycin. | Transplantation proceedings 20101101 |
| Impact of mammalian target of rapamycin inhibition on autosomal-dominant polycystic kidney disease. | Transplantation proceedings 20101101 |
| The therapy of kidney cancer with biomolecular drugs. | Cancer treatment reviews 20101101 |
| Biological targeted therapies in patients with advanced enteropancreatic neuroendocrine carcinomas. | Cancer treatment reviews 20101101 |
| FK506 binding proteins as targets in anticancer therapy. | Anti-cancer agents in medicinal chemistry 20101101 |
| Ras homolog enriched in brain (Rheb) enhances apoptotic signaling. | The Journal of biological chemistry 20101029 |
| Descending serotonergic facilitation mediated by spinal 5-HT3 receptors engages spinal rapamycin-sensitive pathways in the rat. | Neuroscience letters 20101029 |
| Mammalian target of rapamycin controls dendritic cell development downstream of Flt3 ligand signaling. | Immunity 20101029 |
| mTOR inhibition by everolimus counteracts VEGF induction by sunitinib and improves anti-tumor activity against gastric cancer in vivo. | Cancer letters 20101028 |
| Assessment of efficacy and safety of FK778 in comparison with standard care in renal transplant recipients with untreated BK nephropathy. | Transplantation 20101027 |
| [New possibilities of targeted therapy in the treatment of hepatocellular carcinoma with the help of molecular biology]. | Orvosi hetilap 20101024 |
| Phase I studies of drug combinations. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020 |
| Phase IB study of the mTOR inhibitor ridaforolimus with capecitabine. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101020 |
| Generation of high rapamycin producing strain via rational metabolic pathway-based mutagenesis and further titer improvement with fed-batch bioprocess optimization. | Biotechnology and bioengineering 20101015 |
| Rapamycin suppresses the expansion and differentiation of porcine neonatal pancreas cell clusters. | Transplantation 20101015 |
| Combined administration of a mutant TGF-beta1/Fc and rapamycin promotes induction of regulatory T cells and islet allograft tolerance. | Journal of immunology (Baltimore, Md. : 1950) 20101015 |
| Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target of rapamycin and epidermal growth factor receptor in a preclinical model of pancreatic neuroendocrine carcinogenesis. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101010 |
| Small tumors, intermediate models, big hopes. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20101010 |
| Steady-state kinetic and inhibition studies of the mammalian target of rapamycin (mTOR) kinase domain and mTOR complexes. | Biochemistry 20101005 |
| Comparison of zotarolimus-eluting stents with sirolimus- and paclitaxel-eluting stents for coronary revascularization: the ZEST (comparison of the efficacy and safety of zotarolimus-eluting stent with sirolimus-eluting and paclitaxel-eluting stent for coronary lesions) randomized trial. | Journal of the American College of Cardiology 20101005 |
| Tacrolimus-eluting carbon-coated stents versus sirolimus-eluting stents for prevention of symptom-driven clinical end points. | Clinical research in cardiology : official journal of the German Cardiac Society 20101001 |
| Rapamycin sensitizes Akt inhibition in malignant human breast epithelial cells. | Cancer letters 20101001 |
| Autoimmune cytopaenia after paediatric intestinal transplantation: a case series. | Transplant international : official journal of the European Society for Organ Transplantation 20101001 |
| Early withdrawal of calcineurin inhibitors and everolimus monotherapy in de novo liver transplant recipients preserves renal function. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001 |
| A phase I-II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors. | Annals of oncology : official journal of the European Society for Medical Oncology 20101001 |
| Sirolimus oral ulcer with Cedecea davisae superinfection. | Transplant infectious disease : an official journal of the Transplantation Society 20101001 |
| Sirolimus addition to tacrolimus-based immunosuppression induces complete remission of post-transplant lymphoproliferative disorder in a liver transplant recipient. | Transplant international : official journal of the European Society for Organ Transplantation 20101001 |
| Amyloid-beta oligomers impair fear conditioned memory in a calcineurin-dependent fashion in mice. | Journal of neuroscience research 20101001 |
| Immunosuppressive therapy and infection after kidney transplantation. | Transplant infectious disease : an official journal of the Transplantation Society 20101001 |
| Pharmacological inhibition of the mammalian target of rapamycin pathway suppresses acquired epilepsy. | Neurobiology of disease 20101001 |
| Influence of combined treatment of low dose rapamycin and cyclosporin A on corneal allograft survival. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20101001 |
| Activation of mammalian target of rapamycin signaling in spatial learning. | Neuroscience research 20101001 |
| Gingival overgrowth in subjects under immunosuppressive regimens based on cyclosporine, tacrolimus, or sirolimus. | Journal of clinical periodontology 20101001 |
| Novel mechanism of reducing tumourigenesis: upregulation of the DNA repair enzyme OGG1 by rapamycin-mediated AMPK activation and mTOR inhibition. | European journal of cancer (Oxford, England : 1990) 20101001 |
| Evaluation of two sirolimus assays using the ARCHITECT-i1000(®) CMIA or RxL(®) ACMIA methods in comparison with the IMx(®) MEIA method. | Clinical chemistry and laboratory medicine 20101001 |
| β-Amyloid regulates leptin expression and tau phosphorylation through the mTORC1 signaling pathway. | Journal of neurochemistry 20101001 |
| Activation of the mammalian target of rapamycin signaling pathway in hepatocellular carcinoma. | Hepatology (Baltimore, Md.) 20101001 |
| Sirolimus attenuates disease progression in an orthologous mouse model of human autosomal dominant polycystic kidney disease. | Kidney international 20101001 |
| Short- and mid-term intravascular ultrasound analysis of the new zotarolimus-eluting stent with durable polymer – results from the RESOLUTE trial –. | Circulation journal : official journal of the Japanese Circulation Society 20101001 |
| Biological agents in kidney transplantation: belatacept is entering the field. | Expert opinion on biological therapy 20101001 |
| Angiographic, IVUS and OCT evaluation of the long-term impact of coronary disease severity at the site of overlapping drug-eluting and bare metal stents: a substudy of the ODESSA trial. | Heart (British Cardiac Society) 20101001 |
| Effect of rapamycin, an mTOR inhibitor, on radiation sensitivity of lung cancer cells having different p53 gene status. | International journal of oncology 20101001 |
| Use of sirolimus in liver transplant recipients with renal insufficiency: a systematic review and meta-analysis. | Hepatology (Baltimore, Md.) 20101001 |
| Autophagy-induced regression of hyaloid vessels in early ocular development. | Autophagy 20101001 |
| Late vascular responses from 2 to 4 years after implantation of sirolimus-eluting stents: serial observations by intracoronary optical coherence tomography. | Circulation. Cardiovascular interventions 20101001 |
| Temsirolimus: In relapsed and/or refractory mantle cell lymphoma. | Drugs 20101001 |
| De novo therapy with everolimus, low-dose ciclosporine A, basiliximab and steroid elimination in pediatric kidney transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001 |
| Loss of nephrin expression in glomeruli of kidney-transplanted patients under m-TOR inhibitor therapy. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001 |
| 18F-FLT PET as a surrogate marker of drug efficacy during mTOR inhibition by everolimus in a preclinical cisplatin-resistant ovarian tumor model. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20101001 |
| Intravascular ultrasound findings of stent fractures in patients with Sirolimus- and Paclitaxel-eluting stents. | The American journal of cardiology 20101001 |
| Monitoring molecular-specific pharmacodynamics of rapamycin in vivo with inducible Gal4->Fluc transgenic reporter mice. | Molecular cancer therapeutics 20101001 |
| Phase II trial of gefitinib and everolimus in advanced non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20101001 |
| Everolimus: a proliferation signal inhibitor with clinical applications in organ transplantation, oncology, and cardiology. | Pharmacotherapy 20101001 |
| Rapamycin regulates stearoyl CoA desaturase 1 expression in breast cancer. | Molecular cancer therapeutics 20101001 |
| Effect of sirolimus on renal injury induced by bile duct ligation in rats. | Acta cirurgica brasileira 20101001 |
| Diaphragm rupture in a liver transplant patient receiving chronic immunosuppressive therapy with sirolimus. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20101001 |
| Rapamycin as an alternative to surgical treatment of subependymal giant cell astrocytomas in a patient with tuberous sclerosis complex. | Journal of neurosurgery. Pediatrics 20101001 |
| Dramatic improvement in pulmonary hypertension with rapamycin. | Chest 20101001 |
| Does early (CNI) conversion lead to eternal (renal) salvation? | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20101001 |
| Rapid adoption of drug-eluting stents: clinical practices and outcomes from the early drug-eluting stent era. | American heart journal 20101001 |
| Serial angiographic findings and prognosis of stent fracture site without early restenosis after sirolimus-eluting stent implantation. | American heart journal 20101001 |
| Oct1 is required for mTOR-induced G1 cell cycle arrest via the control of p27(Kip1) expression. | Cell cycle (Georgetown, Tex.) 20101001 |
| Current status of the Xience V® everolimus-eluting coronary stent system. | Expert review of cardiovascular therapy 20101001 |
| Paclitaxel-coated balloons - Survey of preclinical data. | Minerva cardioangiologica 20101001 |
| Two-year clinical outcomes after large coronary stent (4.0 mm) placement: comparison of bare-metal stent versus drug-eluting stent. | Clinical cardiology 20101001 |
| Improved late clinical safety with zotarolimus-eluting stents compared with paclitaxel-eluting stents in patients with de novo coronary lesions: 3-year follow-up from the ENDEAVOR IV (Randomized Comparison of Zotarolimus- and Paclitaxel-Eluting Stents in Patients With Coronary Artery Disease) trial. | JACC. Cardiovascular interventions 20101001 |
| The unrestricted use of sirolimus- and paclitaxel-eluting stents results in better clinical outcomes during 6-year follow-up than bare-metal stents: an analysis of the RESEARCH (Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated At Rotterdam Cardiology Hospital) registries. | JACC. Cardiovascular interventions 20101001 |
| Different patterns of vascular response between patients with or without diabetes mellitus after drug-eluting stent implantation: optical coherence tomographic analysis. | JACC. Cardiovascular interventions 20101001 |
| Late conversion to mammalian target of rapamycin inhibitor/proliferation signal inhibitors in kidney transplant patients: clinical experience in the last 5 years. | Transplantation proceedings 20101001 |
| Proliferation signal inhibitors in heart transplantation: a 5-year experience. | Transplantation proceedings 20101001 |
| Temporal trends in the use of proliferation signal inhibitors in maintenance heart transplantation: a Spanish multicenter study. | Transplantation proceedings 20101001 |
| Evaluation of a fully automated method for the determination of sirolimus. | Transplantation proceedings 20101001 |
| Comparative analysis of adverse events requiring suspension of mTOR inhibitors: everolimus versus sirolimus. | Transplantation proceedings 20101001 |
| Pneumonitis associated with mammalian target of rapamycin inhibitors in renal transplant recipients: a single-center experience. | Transplantation proceedings 20101001 |
| Clinical outcomes and cost-utility after sirolimus-eluting versus bare metal stent implantation. | Chinese medical journal 20101001 |
| Androgen receptor-mTOR crosstalk is regulated by testosterone availability: implication for prostate cancer cell survival. | Anticancer research 20101001 |
| Antiproliferative effects of rapamycin and celecoxib in angiosarcoma cell lines. | Anticancer research 20101001 |
| Everolimus for the second-line treatment of advanced and/or metastatic renal cell cancer: a critique of the submission from Novartis. | Health technology assessment (Winchester, England) 20101001 |
| Modulation of ghrelin O-acyltransferase expression in pancreatic islets. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20101001 |
| Comment on 'Infantile spasms: a U.S. consensus report'. | Epilepsia 20101001 |
| Rapamycin protects heart from ischemia/reperfusion injury independent of autophagy by activating PI3 kinase-Akt pathway and mitochondria K(ATP) channel. | Die Pharmazie 20101001 |
| [Efficacy comparison of primary percutaneous coronary intervention with biodegradable polymer- and durable polymer-based sirolimus-eluting stents for patients with acute myocardial infarction]. | Zhonghua xin xue guan bing za zhi 20101001 |
| Combination therapy in patients with metastatic renal cell carcinoma. | Clinical advances in hematology & oncology : H&O 20101001 |
| Recent advances in the discovery of small molecule mTOR inhibitors. | Future medicinal chemistry 20101001 |
| Prolonging hormone sensitivity in prostate cancer xenografts through dual inhibition of AR and mTOR. | British journal of cancer 20100928 |
| Improvement in renal function after late conversion to sirolimus-based immunosuppression in composite tissue allotransplantation. | Transplantation 20100927 |
| Clinical outcomes after implantation of small diameter (=2.5 mm) sirolimus- versus paclitaxel-eluting stents. | International journal of cardiology 20100924 |
| Dual-color click beetle luciferase heteroprotein fragment complementation assays. | Chemistry & biology 20100924 |
| [Everolimus-associated pneumonitis in adult liver transplant recipient]. | Medicina clinica 20100918 |
| Phase 3 trial of everolimus for metastatic renal cell carcinoma : final results and analysis of prognostic factors. | Cancer 20100915 |
| Visceral Kaposi's sarcoma remission after intestinal transplant. First case report and systematic literature review. | Transplantation 20100915 |
| Effect of coronary target lesion revascularization on late cardiac events after insertion of sirolimus-eluting or bare metal stents. | The American journal of cardiology 20100915 |
| Safety and efficacy of the combination of erlotinib and sirolimus for the treatment of metastatic renal cell carcinoma after failure of sunitinib or sorafenib. | British journal of cancer 20100907 |
| Treatment of prostate and breast tumors employing mono- and bi-specific antisense oligonucleotides targeting apoptosis inhibitory proteins clusterin and bcl-2. | Medical oncology (Northwood, London, England) 20100901 |
| Spontaneous pyopneumothorax in patients treated with mTOR inhibitors for subpleural pulmonary metastases. | Medical oncology (Northwood, London, England) 20100901 |
| Targeted agents in metastatic Xp11 translocation/TFE3 gene fusion renal cell carcinoma (RCC): a report from the Juvenile RCC Network. | Annals of oncology : official journal of the European Society for Medical Oncology 20100901 |
| Combination of clopidogrel and everolimus dramatically reduced the development of transplant arteriosclerosis in murine aortic allografts. | Transplant international : official journal of the European Society for Organ Transplantation 20100901 |
| Phosphorylated mTOR expression is associated with poor prognosis for patients with esophageal squamous cell carcinoma. | Annals of surgical oncology 20100901 |
| Compensatory activation of Akt in response to mTOR and Raf inhibitors - a rationale for dual-targeted therapy approaches in neuroendocrine tumor disease. | Cancer letters 20100901 |
| Rapamycin-induced phosphaturia. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100901 |
| Cell-type- and cell-cycle-specific anti-mitogenesis by cicaprost. | Prostaglandins & other lipid mediators 20100901 |
| Severe sirolimus-induced acute hepatitis in a renal transplant recipient. | Transplant international : official journal of the European Society for Organ Transplantation 20100901 |
| Identification of p27/KIP1 expression level as a candidate biomarker of response to rapalogs therapy in human cancer. | Journal of molecular medicine (Berlin, Germany) 20100901 |
| Everolimus as a new potential antiproliferative agent in aggressive human bronchial carcinoids. | Endocrine-related cancer 20100901 |
| Rapamycin induces growth retardation by disrupting angiogenesis in the growth plate. | Kidney international 20100901 |
| Bevacizumab and everolimus in the treatment of patients with metastatic melanoma: a phase 2 trial of the Sarah Cannon Oncology Research Consortium. | Cancer 20100901 |
| Antiproliferation of cardamonin is involved in mTOR on aortic smooth muscle cells in high fructose-induced insulin resistance rats. | European journal of pharmacology 20100901 |
| Coronary microvascular endothelial function deteriorates late (12 months) after sirolimus-eluting stent implantation. | Journal of cardiology 20100901 |
| Choice of stenting strategy in true coronary artery bifurcation lesions. | Coronary artery disease 20100901 |
| Cutaneous T-cell lymphoma cells are sensitive to rapamycin. | Experimental dermatology 20100901 |
| Pilot study: rapamycin in advanced hepatocellular carcinoma. | Alimentary pharmacology & therapeutics 20100901 |
| Human chorionic gonadotropin stimulates theca-interstitial cell proliferation and cell cycle regulatory proteins by a cAMP-dependent activation of AKT/mTORC1 signaling pathway. | Molecular endocrinology (Baltimore, Md.) 20100901 |
| Everolimus: efficacy and safety in cardiac transplantation. | Expert opinion on drug safety 20100901 |
| Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens. | EMBO molecular medicine 20100901 |
| Autophagy induction with RAD001 enhances chemosensitivity and radiosensitivity through Met inhibition in papillary thyroid cancer. | Molecular cancer research : MCR 20100901 |
| Rapamycin and thalidomide treatment of a patient with refractory metastatic gastroesophageal adenocarcinoma: a case report. | The oncologist 20100901 |
| [Second line AUO study AB35/09 of metastasized urothelial cell carcinoma]. | Der Urologe. Ausg. A 20100901 |
| Can autophagy promote longevity? | Nature cell biology 20100901 |
| Updates of mTOR inhibitors. | Anti-cancer agents in medicinal chemistry 20100901 |
| Vulnerable disease may induce neointimal coverage after sirolimus-eluting stent implantation. | American heart journal 20100901 |
| Everolimus-eluting stents: insights from the SPIRIT IV and COMPARE trials. | Expert review of cardiovascular therapy 20100901 |
| Percutaneous coronary intervention for small-vessel coronary disease: highlight on the everolimus-eluting stent. | Expert review of cardiovascular therapy 20100901 |
| Bone disease in renal transplantation and pleotropic effects of vitamin D therapy. | Transplantation proceedings 20100901 |
| Sirolimus-induced isometric tubular vacuolization: a new sirolimus histopathologic manifestation. | Transplantation proceedings 20100901 |
| Timing of conversion to mammalian target of rapamycin inhibitors is crucial in liver transplant recipients with impaired renal function at transplantation. | Transplantation proceedings 20100901 |
| Sirolimus in liver transplant recipients: a large single-center experience. | Transplantation proceedings 20100901 |
| Influence of immunosuppressive drugs on the development of CD4(+)CD25(high) Foxp3(+) T cells in liver transplant recipients. | Transplantation proceedings 20100901 |
| Sirolimus is associated with impaired hematopoiesis in heart transplant patients? A retrospective analysis. | Transplantation proceedings 20100901 |
| American Society of Clinical Oncology 2010: report of selected studies from the CNS tumors section. | Expert review of anticancer therapy 20100901 |
| Comparison of sirolimus- and paclitaxel-eluting stents in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction: a meta-analysis of randomized trials. | Clinical cardiology 20100901 |
| mTOR pathway inhibitors in cancer therapy: moving past rapamycin. | Pharmacogenomics 20100901 |
| Rapamycin and MPA, but not CsA, impair human NK cell cytotoxicity due to differential effects on NK cell phenotype. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100901 |
| Comparison of everolimus-eluting and paclitaxel-eluting coronary stents in patients with two treated vessels: 2-year results from the SPIRIT III randomised trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901 |
| Three-year results of clinical follow-up after a bioresorbable everolimus-eluting scaffold in patients with de novo coronary artery disease: the ABSORB trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901 |
| Impact of arterial injury on neointimal hyperplasia after implantation of drug-eluting stents in coronary arteries: an intravascular ultrasound study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901 |
| Vascular response to a third generation everolimus-eluting stent. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100901 |
| Differential expression of mTOR signalling components in drug resistance in ovarian cancer. | Anticancer research 20100901 |
| Ridaforolimus. | Drugs in R&D 20100901 |
| Inflammation inhibitory effects of sirolimus and paclitaxel-eluting stents on interleukin-1β-induced coronary artery in-stent restenosis in pigs. | Chinese medical journal 20100901 |
| [Inhibition of cell growth by rapamycin through targeting mammalian target of rapamycin signaling pathway in nasopharyngeal carcinoma]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20100901 |
| Antihyperalgesic and antiallodynic effect of sirolimus in neuropathic pain and the role of cytokines in this effect. | Neuroscience letters 20100830 |
| Murine cytomegalovirus infection leads to increased levels of transplant arteriosclerosis in a murine aortic allograft model. | Transplantation 20100827 |
| Sirolimus and kidney growth in autosomal dominant polycystic kidney disease. | The New England journal of medicine 20100826 |
| Everolimus in patients with autosomal dominant polycystic kidney disease. | The New England journal of medicine 20100826 |
| mTOR inhibitors in polycystic kidney disease. | The New England journal of medicine 20100826 |
| Rapamycin activates autophagy and improves myelination in explant cultures from neuropathic mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100825 |
| Integrated preclinical and clinical development of mTOR inhibitors in pancreatic cancer. | British journal of cancer 20100824 |
| Dual inhibition of EGFR and mTOR pathways in small cell lung cancer. | British journal of cancer 20100824 |
| Regulation of the autophagy protein LC3 by phosphorylation. | The Journal of cell biology 20100823 |
| Resistance to mammalian target of rapamycin inhibitor therapy in perivascular epithelioid cell tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100820 |
| Neuroscience. A glutamate pathway to faster-acting antidepressants? | Science (New York, N.Y.) 20100820 |
| mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists. | Science (New York, N.Y.) 20100820 |
| Correlation of tissue drug concentrations with in vivo magnetic resonance images of polymer drug depot around arteriovenous graft. | Journal of controlled release : official journal of the Controlled Release Society 20100817 |
| Early and late effects of the immunosuppressants rapamycin and mycophenolate mofetil on UV carcinogenesis. | International journal of cancer 20100815 |
| Phase 1 and pharmacokinetic study of everolimus, a mammalian target of rapamycin inhibitor, in combination with docetaxel for recurrent/refractory nonsmall cell lung cancer. | Cancer 20100815 |
| Intermittent antibody-based combination therapy removes alloantibodies and achieves indefinite heart transplant survival in presensitized recipients. | Transplantation 20100815 |
| Cutting edge: Rapamycin augments pathogen-specific but not graft-reactive CD8+ T cell responses. | Journal of immunology (Baltimore, Md. : 1950) 20100815 |
| Manipulating signal delivery - plasma-membrane ERK activation in aPKC-dependent migration. | Journal of cell science 20100815 |
| Dvl2 promotes intestinal length and neoplasia in the ApcMin mouse model for colorectal cancer. | Cancer research 20100815 |
| Comparison of everolimus- versus paclitaxel-eluting stents implanted in patients with diabetes mellitus as evaluated by three-dimensional intravascular ultrasound analysis. | The American journal of cardiology 20100815 |
| Three-year outcomes following sirolimus- versus paclitaxel-eluting stent implantation in an unselected population with coronary artery disease (from the REWARDS Registry). | The American journal of cardiology 20100815 |
| A novel clinically relevant approach to tip the balance toward regulation in stringent transplant model. | Transplantation 20100815 |
| Revisiting the antagonistic pleiotropy theory of aging: TOR-driven program and quasi-program. | Cell cycle (Georgetown, Tex.) 20100815 |
| Altered VEGF mRNA stability following treatments with immunosuppressive agents: implications for cancer development. | The Journal of biological chemistry 20100813 |
| A novel Ca2+/calmodulin antagonist HBC inhibits angiogenesis and down-regulates hypoxia-inducible factor. | The Journal of biological chemistry 20100813 |
| MLK3 is critical for breast cancer cell migration and promotes a malignant phenotype in mammary epithelial cells. | Oncogene 20100805 |
| Deregulation of the PI3K and KRAS signaling pathways in human cancer cells determines their response to everolimus. | The Journal of clinical investigation 20100802 |
| PIK3CA and KRAS mutations predict for response to everolimus therapy: now that's RAD001. | The Journal of clinical investigation 20100802 |
| The activity of mTOR inhibitor RAD001 (everolimus) in nasopharyngeal carcinoma and cisplatin-resistant cell lines. | Investigational new drugs 20100801 |
| Large-scale expansion of pluripotent human embryonic stem cells in stirred-suspension bioreactors. | Tissue engineering. Part C, Methods 20100801 |
| Sirolimus attenuates reduced-size liver ischemia-reperfusion injury but impairs liver regeneration in rats. | Digestive diseases and sciences 20100801 |
| Enzastaurin (LY317615), a protein kinase C beta selective inhibitor, enhances antiangiogenic effect of radiation. | International journal of radiation oncology, biology, physics 20100801 |
| Effect of everolimus on skin cancers in calcineurin inhihitor-treated heart transplant recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20100801 |
| Fatal diffuse alveolar hemorrhage associated with sirolimus after allogeneic hematopoietic cell transplantation. | Bone marrow transplantation 20100801 |
| Sirolimus for treatment of steroid-refractory acute graft-versus-host disease. | Bone marrow transplantation 20100801 |
| Sirolimus in renal transplant recipients with tuberous sclerosis complex: clinical effectiveness and implications for innate immunity. | Transplant international : official journal of the European Society for Organ Transplantation 20100801 |
| Combination of tipifarnib and rapamycin synergistically inhibits the growth of leukemia cells and overcomes resistance to tipifarnib via alteration of cellular signaling pathways. | Leukemia research 20100801 |
| Metformin and rapamycin have distinct effects on the AKT pathway and proliferation in breast cancer cells. | Breast cancer research and treatment 20100801 |
| Noninfectious pneumonitis after everolimus therapy for advanced renal cell carcinoma. | American journal of respiratory and critical care medicine 20100801 |
| Neoadjuvant temsirolimus effectiveness in downstaging advanced non-clear cell renal cell carcinoma. | European urology 20100801 |
| IGFBP-2 expression in MCF-7 cells is regulated by the PI3K/AKT/mTOR pathway through Sp1-induced increase in transcription. | Growth factors (Chur, Switzerland) 20100801 |
| Surface characterization of poly(lactic acid)/everolimus and poly(ethylene vinyl alcohol)/everolimus stents. | Drug delivery 20100801 |
| Inhibition of mTORC1 by RAD001 (everolimus) potentiates the effects of 1,25-dihydroxyvitamin D(3) to induce growth arrest and differentiation of AML cells in vitro and in vivo. | Experimental hematology 20100801 |
| Loss of single immunoglobulin interlukin-1 receptor-related molecule leads to enhanced colonic polyposis in Apc(min) mice. | Gastroenterology 20100801 |
| A spectrophotometric assay for routine measurement of mammalian target of rapamycin activity in cell lysates. | Analytical biochemistry 20100801 |
| A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors. | Japanese journal of clinical oncology 20100801 |
| Drug-eluting stents ameliorate pulmonary vein stenotic changes in pigs in vivo. | Pediatric cardiology 20100801 |
| Sirolimus has a potential to influent viral recurrence in HCV positive liver transplant candidates. | International immunopharmacology 20100801 |
| Pulmonary alveolar proteinosis in a kidney transplant: a rare complication of sirolimus. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100801 |
| Endocrine control of oleic acid and glucose metabolism in rainbow trout (Oncorhynchus mykiss) muscle cells in culture. | American journal of physiology. Regulatory, integrative and comparative physiology 20100801 |
| Mammalian target of rapamycin signaling is crucial for joint destruction in experimental arthritis and is activated in osteoclasts from patients with rheumatoid arthritis. | Arthritis and rheumatism 20100801 |
| Treatment with rapamycin prevents fibrosis in tight-skin and bleomycin-induced mouse models of systemic sclerosis. | Arthritis and rheumatism 20100801 |
| Increased serum vWF and sVCAM-1 levels are associated with late or very late angiographic stent thrombosis after sirolimus-eluting stent implantation. | Coronary artery disease 20100801 |
| Intravascular ultrasound criteria for determination of optimal longitudinal positioning of sirolimus-eluting stents. | Circulation journal : official journal of the Japanese Circulation Society 20100801 |
| Liquid chromatography-tandem mass spectrometry outperforms fluorescence polarization immunoassay in monitoring everolimus therapy in renal transplantation. | Therapeutic drug monitoring 20100801 |
| Effective targeting of STAT5-mediated survival in myeloproliferative neoplasms using ABT-737 combined with rapamycin. | Leukemia 20100801 |
| Effects of sirolimus alone or in combination with cyclosporine A on renal ischemia/reperfusion injury. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100801 |
| Protein denaturation and protein:drugs interactions from intrinsic protein fluorescence measurements at the nanolitre scale. | Protein science : a publication of the Protein Society 20100801 |
| Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease. | Molecular genetics and metabolism 20100801 |
| Beclin 1 self-association is independent of autophagy induction by amino acid deprivation and rapamycin treatment. | Journal of cellular biochemistry 20100801 |
| Comparison of sirolimus-eluting and bare metal stent for treatment of patients with total coronary occlusions: results of the GISSOC II-GISE multicentre randomized trial. | European heart journal 20100801 |
| New inhibitors of the mammalian target of rapamycin signaling pathway for cancer. | Expert opinion on investigational drugs 20100801 |
| Sirolimus and mycophenolate as combination prophylaxis in corneal transplant recipients at high rejection risk. | American journal of ophthalmology 20100801 |
| TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation. | Development (Cambridge, England) 20100801 |
| The application of the National Institute of Clinical Excellence guidelines for treatment of metastatic renal cell carcinoma in the United Kingdom: friend or foe? | BJU international 20100801 |
| Biosynthesis of rapamycin and its regulation: past achievements and recent progress. | The Journal of antibiotics 20100801 |
| Differential proteome and phosphoproteome signatures in human T-lymphoblast cells induced by sirolimus. | Cell proliferation 20100801 |
| In vitro effects of everolimus and intravenous immunoglobulin on cell proliferation and apoptosis induction in the mixed lymphocyte reaction. | Transplant immunology 20100801 |
| Do drug elution components increase the risk of fracture of sirolimus-eluting stents? | Coronary artery disease 20100801 |
| Conversion to sirolimus in renal transplant recipients: a single-center experience. | Artificial organs 20100801 |
| Everolimus in the treatment of renal cell carcinoma and neuroendocrine tumors. | Advances in therapy 20100801 |
| Rapamycin-conditioned donor dendritic cells differentiate CD4CD25Foxp3 T cells in vitro with TGF-beta1 for islet transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100801 |
| Incidence and risk factors of late target lesion revascularization after sirolimus-eluting stent implantation (3-year follow-up of the j-Cypher Registry). | The American journal of cardiology 20100801 |
| Comparison of sirolimus-eluting stents with paclitaxel-eluting stents in saphenous vein graft intervention (from a multicenter Southern California Registry). | The American journal of cardiology 20100801 |
| The combination of multiple receptor tyrosine kinase inhibitor and mammalian target of rapamycin inhibitor overcomes erlotinib resistance in lung cancer cell lines through c-Met inhibition. | Molecular cancer research : MCR 20100801 |
| Progeria syndromes and ageing: what is the connection? | Nature reviews. Molecular cell biology 20100801 |
| Islet transplantation in type 1 diabetics using an immunosuppressive protocol based on the anti-LFA-1 antibody efalizumab. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100801 |
| Off-label prescribing: a matter of trust. | Nature reviews. Nephrology 20100801 |
| Elevated high sensitive C-reactive protein and apelin levels after percutaneous coronary intervention and drug-eluting stent implantation. | Journal of Zhejiang University. Science. B 20100801 |
| Very late thrombosis after subintimal sirolimus-eluting stent implantation during percutaneous coronary intervention for chronic total occlusion. | The Journal of invasive cardiology 20100801 |
| Primary use of sirolimus-eluting stents in the infrapopliteal arteries. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20100801 |
| Commentary: infrapopliteal angioplasty with drug-eluting stents: from heart to toe. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20100801 |
| Xenohormetic, hormetic and cytostatic selective forces driving longevity at the ecosystemic level. | Aging 20100801 |
| How does the mammalian target of rapamycin (mTOR) influence CD8 T cell differentiation? | Cell cycle (Georgetown, Tex.) 20100801 |
| Different patterns of BK and JC polyomavirus reactivation following renal transplantation. | Journal of clinical pathology 20100801 |
| Targeted therapy at the end of life for patients with lung cancer. | Journal of palliative medicine 20100801 |
| New drug-eluting stents: an overview on biodegradable and polymer-free next-generation stent systems. | Circulation. Cardiovascular interventions 20100801 |
| 3-Dimensional optical coherence tomography assessment of jailed side branches by bioresorbable vascular scaffolds: a proposal for classification. | JACC. Cardiovascular interventions 20100801 |
| Effect of oral sirolimus therapy on inflammatory biomarkers following coronary stenting. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20100801 |
| Arnold Lester Demain: a good friend, an outstanding scientist and a valuable professor. | The Journal of antibiotics 20100801 |
| Everolimus in renal cell carcinoma. | Drugs of today (Barcelona, Spain : 1998) 20100801 |
| Short and long term comparison (24 months) of an alternative sirolimus-coated stent with bioabsorbable polymer and a bare metal stent of similar design in chronic coronary occlusions: the CORACTO trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801 |
| Intravascular ultrasound, angioscopic and histopathological characterisation of heterogeneous patterns of restenosis after sirolimus-eluting stent implantation: insights into potential 'thromborestenosis' phenomenon. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801 |
| A quantitative coronary angiography-matched comparison between a prospective randomised multicentre cutting balloon angioplasty and bare metal stent trial (REDUCE III) and the Rapamycin-Eluting Stent Evaluation At Rotterdam Cardiology Hospital (RESEARCH) study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100801 |
| The combination of sirolimus and rosiglitazone produces a renoprotective effect on diabetic kidney disease in rats. | Life sciences 20100731 |
| Rapamycin promotes beta-amyloid production via ADAM-10 inhibition. | Biochemical and biophysical research communications 20100730 |
| Modulation of high-voltage activated Ca(2+) channels by membrane phosphatidylinositol 4,5-bisphosphate. | Neuron 20100729 |
| Renal function, efficacy, and safety of sirolimus and mycophenolate mofetil after short-term calcineurin inhibitor-based quadruple therapy in de novo renal transplant patients: one-year analysis of a randomized multicenter trial. | Transplantation 20100727 |
| Effect of sirolimus on calcineurin inhibitor-induced nephrotoxicity using renal expression of KLOTHO, an antiaging gene. | Transplantation 20100727 |
| The TOR complex 1 is distributed in endosomes and in retrograde vesicles that form from the vacuole membrane and plays an important role in the vacuole import and degradation pathway. | The Journal of biological chemistry 20100723 |
| Identification of Pep4p as the protease responsible for formation of the SAGA-related SLIK protein complex. | The Journal of biological chemistry 20100723 |
| [Chronic renal failure is associated with worse outcome after implantation of sirolimus eluting stent]. | Medicina clinica 20100717 |
| Selective induction of catalase-mediated autophagy by dihydrocapsaicin in lung cell lines. | Free radical biology & medicine 20100715 |
| Enteric-coated mycophenolate sodium versus mycophenolate mofetil maintenance immunosuppression: outcomes analysis of the United Network for Organ Sharing/Organ Procurement and Transplantation Network database. | Transplantation 20100715 |
| R1507, a fully human monoclonal antibody targeting IGF-1R, is effective alone and in combination with rapamycin in inhibiting growth of osteosarcoma xenografts. | Pediatric blood & cancer 20100715 |
| Optimal everolimus concentration is associated with risk reduction for acute rejection in de novo renal transplant recipients. | Transplantation 20100715 |
| mTORC1 signaling in Parkinson's disease and L-DOPA-induced dyskinesia: A sensitized matter. | Cell cycle (Georgetown, Tex.) 20100715 |
| The efficacy of the novel dual PI3-kinase/mTOR inhibitor NVP-BEZ235 compared with rapamycin in renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100715 |
| Comparison of zotarolimus-eluting and everolimus-eluting coronary stents. | The New England journal of medicine 20100708 |
| Sirolimus-eluting stent versus balloon angioplasty for sirolimus-eluting stent restenosis: Insights from the j-Cypher Registry. | Circulation 20100706 |
| Comparisons of baseline demographics, clinical presentation, and long-term outcome among patients with early, late, and very late stent thrombosis of sirolimus-eluting stents: Observations from the Registry of Stent Thrombosis for Review and Reevaluation (RESTART). | Circulation 20100706 |
| Sirolimus therapy for fibromatosis and multifocal renal cell carcinoma in a child with tuberous sclerosis complex. | Pediatric blood & cancer 20100701 |
| Effect of combination treatment of rapamycin and isoflavones on mTOR pathway in human glioblastoma (U87) cells. | Neurochemical research 20100701 |
| Antiangiogenic effects and transcriptional regulation of pigment epithelium-derived factor in diabetic retinopathy. | Microvascular research 20100701 |
| Inhibition of MEK/ERK signaling induces apoptosis of acute myelogenous leukemia cells via inhibition of eukaryotic initiation factor 4E-binding protein 1 and down-regulation of Mcl-1. | Apoptosis : an international journal on programmed cell death 20100701 |
| Inhibition of mTORC1 signaling reduces tumor growth but does not prevent cancer progression in a mouse model of thyroid cancer. | Carcinogenesis 20100701 |
| Four-year clinical outcome of sirolimus- and paclitaxel-eluting stents compared to bare-metal stents for the percutaneous treatment of stable coronary artery disease. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701 |
| In vitro and in vivo changes to PLGA/sirolimus coating on drug eluting stents. | Biomaterials 20100701 |
| MTOR downregulates iodide uptake in thyrocytes. | The Journal of endocrinology 20100701 |
| Gingival overgrowth in cyclosporine, tacrolimus, or sirolimus-based immunosuppressive regimens and the single nucleotide IL-6 (-174 G/C) gene polymorphism. | Archives of oral biology 20100701 |
| Regulation of the creatine transporter by AMP-activated protein kinase in kidney epithelial cells. | American journal of physiology. Renal physiology 20100701 |
| New developments in targeted therapy for soft tissue sarcoma. | Current oncology reports 20100701 |
| Sirolimus and everolimus reduce albumin endocytosis in proximal tubule cells via an angiotensin II-dependent pathway. | Transplant immunology 20100701 |
| New drugs in neuroendocrine tumors: rising of new therapeutic philosophies? | Current opinion in oncology 20100701 |
| Gene expression profiling of response to mTOR inhibitor everolimus in pre-operatively treated post-menopausal women with oestrogen receptor-positive breast cancer. | Breast cancer research and treatment 20100701 |
| cAMP-dependent activation of mammalian target of rapamycin (mTOR) in thyroid cells. Implication in mitogenesis and activation of CDK4. | Molecular endocrinology (Baltimore, Md.) 20100701 |
| Complete resolution of oral Kaposi's sarcoma achieved by changing immunosuppression: a case report. | Annals of the Royal College of Surgeons of England 20100701 |
| Hyperactivation of phosphatidylinositol-3 kinase promotes escape from hormone dependence in estrogen receptor-positive human breast cancer. | The Journal of clinical investigation 20100701 |
| Visualization of embryonic lymphangiogenesis advances the use of the zebrafish model for research in cancer and lymphatic pathologies. | Developmental dynamics : an official publication of the American Association of Anatomists 20100701 |
| Outcomes after differential use of drug-eluting stents in diabetic patients: 1-year results from the DES.DE (Drug-Eluting Stent.DEutschland) registry. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701 |
| Which DES for diabetics? Round 1: A draw. Round 2: Everolimus leading? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701 |
| An everolimus-eluting stent versus a paclitaxel-eluting stent in small vessel coronary artery disease: a pooled analysis from the SPIRIT II and SPIRIT III trials. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701 |
| Another small step for small vessels. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100701 |
| [Sirolimus-eluting stent in the prevention of restenosis in small coronary arteries]. | La Tunisie medicale 20100701 |
| Development and performance of the zotarolimus-eluting Endeavor coronary stent. | Expert review of medical devices 20100701 |
| Effectiveness and safety of drug-eluting stents in a cardiology clinic in Curitiba, PR, Brazil. | Arquivos brasileiros de cardiologia 20100701 |
| Recent advances in the development of selective, ATP-competitive inhibitors of mTOR. | Current opinion in drug discovery & development 20100701 |
| Efficacy and safety of rapamycin as compared to paclitaxel-eluting stents: a meta-analysis. | The Journal of invasive cardiology 20100701 |
| Long-term clinical outcome of sirolimus-eluting stent implantation in metabolic syndrome and diabetes. | The Journal of invasive cardiology 20100701 |
| Three-year outcome of sirolimus-eluting versus bare-metal stents for the treatment of ST-segment elevation myocardial infarction (from the MISSION! Intervention Study). | The American journal of cardiology 20100701 |
| SPIRIT III JAPAN versus SPIRIT III USA: a comparative intravascular ultrasound analysis of the everolimus-eluting stent. | The American journal of cardiology 20100701 |
| Therapeutic approaches to epileptogenesis--hope on the horizon. | Epilepsia 20100701 |
| Modeling new therapies for infantile spasms. | Epilepsia 20100701 |
| Clinical recommendations for the use of everolimus in heart transplantation. | Transplantation reviews (Orlando, Fla.) 20100701 |
| Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes. | Aging 20100701 |
| [Current impact of natural products in the discovery of anticancer drugs]. | Annales pharmaceutiques francaises 20100701 |
| Influence of immunosuppression on alloresponse, inflammation and contractile function of graft after intestinal transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100701 |
| Therapeutic mTOR inhibition in autosomal dominant polycystic kidney disease: What is the appropriate serum level? | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100701 |
| Topical rapamycin: a novel approach to facial angiofibromas in tuberous sclerosis. | Archives of dermatology 20100701 |
| Specific coronary drug-eluting stents interfere with distal microvascular function after single stent implantation in pigs. | JACC. Cardiovascular interventions 20100701 |
| [Subacute thrombosis of drug eluting stent immediately after off-pump coronary artery bypass grafting]. | Kyobu geka. The Japanese journal of thoracic surgery 20100701 |
| Temsirolimus: is improved survival the correct expression of drug activity? | The oncologist 20100701 |
| Combination therapy of 5-fluorouracil with rapamycin for hormone receptor-negative human breast cancer. | Anticancer research 20100701 |
| Rapamycin treatment suppresses epileptogenic activity in conditional Pten knockout mice. | Cell cycle (Georgetown, Tex.) 20100701 |
| Thymoglobulin induction and sirolimus versus tacrolimus in kidney transplant recipients receiving mycophenolate mofetil and steroids. | Transplantation 20100627 |
| Oxidative stress changes after stent implantation: a randomized comparative study of sirolimus-eluting and bare metal stents. | International journal of cardiology 20100625 |
| Design of selective, ATP-competitive inhibitors of Akt. | Journal of medicinal chemistry 20100624 |
| Mammalian target of rapamycin (mTOR) and S6 kinase down-regulate phospholipase D2 basal expression and function. | The Journal of biological chemistry 20100618 |
| Randomized trial of paclitaxel- versus sirolimus-eluting stents for treatment of coronary restenosis in sirolimus-eluting stents: the ISAR-DESIRE 2 (Intracoronary Stenting and Angiographic Results: Drug Eluting Stents for In-Stent Restenosis 2) study. | Journal of the American College of Cardiology 20100615 |
| Kinetics of FKBP12.6 binding to ryanodine receptors in permeabilized cardiac myocytes and effects on Ca sparks. | Circulation research 20100611 |
| Structure of the human mTOR complex I and its implications for rapamycin inhibition. | Molecular cell 20100611 |
| Chemically controlled protein assembly: techniques and applications. | Chemical reviews 20100609 |
| 2-year clinical and angiographic outcomes from a randomized trial of polymer-free dual drug-eluting stents versus polymer-based Cypher and Endeavor [corrected] drug-eluting stents. | Journal of the American College of Cardiology 20100608 |
| Distinct phosphatase requirements and GATA factor responses to nitrogen catabolite repression and rapamycin treatment in Saccharomyces cerevisiae. | The Journal of biological chemistry 20100604 |
| Mechanisms involved in the enhancement of mammalian target of rapamycin signalling and hypertrophy in skeletal muscle of myostatin-deficient mice. | FEBS letters 20100603 |
| Feasibility of sequential use of sunitinib and temsirolimus in advanced renal cell carcinoma. | Medical oncology (Northwood, London, England) 20100601 |
| Phase I, pharmacokinetic study of temsirolimus administered orally to patients with advanced cancer. | Investigational new drugs 20100601 |
| Mammalian target of rapamycin (mTOR) is involved in the survival of cells mediated by chemokine receptor 7 through PI3K/Akt in metastatic squamous cell carcinoma of the head and neck. | The British journal of oral & maxillofacial surgery 20100601 |
| Gonadal dysfunction and infertility in kidney transplant patients receiving sirolimus. | International urology and nephrology 20100601 |
| A model of chronic lung allograft rejection in the rat. | The European respiratory journal 20100601 |
| Rapamycin enhances chemotherapy-induced cytotoxicity by inhibiting the expressions of TS and ERK in gastric cancer cells. | International journal of cancer 20100601 |
| Phase Ib study of weekly mammalian target of rapamycin inhibitor ridaforolimus (AP23573; MK-8669) with weekly paclitaxel. | Annals of oncology : official journal of the European Society for Medical Oncology 20100601 |
| Sirolimus-associated acute interstitial nephritis in a renal allograft. | Transplant international : official journal of the European Society for Organ Transplantation 20100601 |
| FAK mediates the activation of cardiac fibroblasts induced by mechanical stress through regulation of the mTOR complex. | Cardiovascular research 20100601 |
| The role of mTOR signaling in controlling mammalian life span: what a fungicide teaches us about longevity. | The journals of gerontology. Series A, Biological sciences and medical sciences 20100601 |
| Correlation between circulating endothelial progenitor cell function and allograft rejection in heart transplant patients. | Transplant international : official journal of the European Society for Organ Transplantation 20100601 |
| Cyclosporine, tacrolimus and sirolimus retain their distinct toxicity profiles despite low doses in the Symphony study. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100601 |
| Switch to a sirolimus-based immunosuppression in long-term renal transplant recipients: reduced rate of (pre-)malignancies and nonmelanoma skin cancer in a prospective, randomized, assessor-blinded, controlled clinical trial. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601 |
| Phosphorylation of PRAS40 on Thr246 by PKB/AKT facilitates efficient phosphorylation of Ser183 by mTORC1. | Cellular signalling 20100601 |
| Long-term complication after LM bifurcation treatment. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601 |
| Proximal protection in recanalization of totally occluded saphenous vein grafts in acute coronary syndrome. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601 |
| Update on systemic therapies of metastatic renal cell carcinoma. | World journal of urology 20100601 |
| Reversible severe synovitis associated with everolimus. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20100601 |
| Central leptin treatment modulates brain glucosensing function and peripheral energy metabolism of rainbow trout. | Peptides 20100601 |
| Substitution of corticosteroid with everolimus after lung transplantation: a pediatric case report. | Pharmacy world & science : PWS 20100601 |
| Pharmacokinetic and pharmacodynamic interactions between the immunosuppressant sirolimus and the lipid-lowering drug ezetimibe in healthy volunteers. | Clinical pharmacology and therapeutics 20100601 |
| PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis. | Experimental eye research 20100601 |
| Sirolimus-based calcineurin inhibitor withdrawal immunosuppressive regimen in kidney transplantation: a single center experience. | Clinical and experimental nephrology 20100601 |
| Downregulation of Akt/mammalian target of rapamycin pathway in skeletal muscle is associated with increased REDD1 expression in response to chronic hypoxia. | American journal of physiology. Regulatory, integrative and comparative physiology 20100601 |
| Chronic rapamycin treatment causes glucose intolerance and hyperlipidemia by upregulating hepatic gluconeogenesis and impairing lipid deposition in adipose tissue. | Diabetes 20100601 |
| Benefit of early conversion from CNI-based to everolimus-based immunosuppression in heart transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20100601 |
| Rhabdomyolysis and acute kidney injury secondary to concomitant use of fluvastatin and rapamycin in a renal transplant recipient. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100601 |
| EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway. | Molecular pharmacology 20100601 |
| The protein kinase CaSch9p is required for the cell growth, filamentation and virulence in the human fungal pathogen Candida albicans. | FEMS yeast research 20100601 |
| A phase I study of weekly temsirolimus and topotecan in the treatment of advanced and/or recurrent gynecologic malignancies. | Gynecologic oncology 20100601 |
| Sirolimus inhibits endogenous cholesterol synthesis induced by inflammatory stress in human vascular smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20100601 |
| Luteinizing hormone stimulates mammalian target of rapamycin signaling in bovine luteal cells via pathways independent of AKT and mitogen-activated protein kinase: modulation of glycogen synthase kinase 3 and AMP-activated protein kinase. | Endocrinology 20100601 |
| The fate of incomplete stent apposition with drug-eluting stents: an optical coherence tomography-based natural history study. | European heart journal 20100601 |
| Late progression after sirolimus-eluting stent implantation for de novo lesions--comparison with bare metal stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20100601 |
| Does tacrolimus, in comparison with sirolimus, increase mycophenolic acid exposure in kidney transplant recipients? | Clinical pharmacology and therapeutics 20100601 |
| Mammalian target of rapamycin (mTOR) regulates cellular proliferation and tumor growth in urothelial carcinoma. | The American journal of pathology 20100601 |
| Emergent toxicities associated with the use of mTOR inhibitors in patients with advanced renal carcinoma. | Anti-cancer drugs 20100601 |
| Effects of vatalanib on tumor growth can be potentiated by mTOR blockade in vivo. | Cancer biology & therapy 20100601 |
| Rapamycin joins the aging fray: maybe Ponce de Leon visited Rapa Nui, not Florida. | The journals of gerontology. Series A, Biological sciences and medical sciences 20100601 |
| Randomized intervention studies in human polycystic kidney and liver disease. | Journal of the American Society of Nephrology : JASN 20100601 |
| Use of pharmacogenetics to optimize immunosuppressive therapy. | Therapeutic drug monitoring 20100601 |
| Development of a novel prohealing stent designed to deliver sirolimus from a biodegradable abluminal matrix. | Circulation. Cardiovascular interventions 20100601 |
| Everolimus plus reduced-exposure CsA versus mycophenolic acid plus standard-exposure CsA in renal-transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601 |
| Treatment of metastatic renal cell carcinoma. | Nature reviews. Urology 20100601 |
| [Treatment of adult patients with metastatic sarcoma: current shift in concepts]. | Bulletin du cancer 20100601 |
| Sirolimus therapy to halt the progression of ADPKD. | Journal of the American Society of Nephrology : JASN 20100601 |
| Optic nerve tumor in tuberous sclerosis complex is not responsive to sirolimus. | Pediatric neurology 20100601 |
| Twelve-month outcomes in patients with diabetes implanted with a zotarolimus-eluting stent: results from the E-Five Registry. | Heart (British Cardiac Society) 20100601 |
| PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer. | Proceedings of the National Academy of Sciences of the United States of America 20100601 |
| Regulation of insulin-like growth factor-mammalian target of rapamycin signaling by microRNA in childhood adrenocortical tumors. | Cancer research 20100601 |
| A pharmacodynamic study of rapamycin in men with intermediate- to high-risk localized prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100601 |
| Rapamycin reduces intrahepatic alpha-1-antitrypsin mutant Z protein polymers and liver injury in a mouse model. | Experimental biology and medicine (Maywood, N.J.) 20100601 |
| Rapamycin regulates Akt and ERK phosphorylation through mTORC1 and mTORC2 signaling pathways. | Molecular carcinogenesis 20100601 |
| Five-year long-term clinical follow-up of the XIENCE V everolimus eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT FIRST trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601 |
| Long-term follow-up of the First In Man experience with everolimus-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601 |
| Percutaneous UPLM revascularisation: the time has come. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100601 |
| Procedure-related myonecrosis after bare and drug-eluting stent implantation. | Asian cardiovascular & thoracic annals 20100601 |
| Current progress in pharmacogenetics and individualized immunosuppressive drug dosing in organ transplantation. | Current opinion in molecular therapeutics 20100601 |
| The TOR pathway modulates the structure of cell walls in Arabidopsis. | The Plant cell 20100601 |
| Rapamycin can inhibit the development of Chlamydia pneumoniae, which might partly contribute to the prevention of in-stent restenosis. | Cardiovascular drugs and therapy 20100601 |
| [mTOR inhibitors]. | Nihon rinsho. Japanese journal of clinical medicine 20100601 |
| The importance of skin cancer prevention in organ transplant patients an editorial to paper by Salgo: 'switch to sirolimus in long-term renal transplant recipients: reduced premalignancies and nonmelanoma skin cancer in a controlled, prospective, randomized, blinded study'. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100601 |
| Clinical and angiographic outcomes of drug-eluting stents in patients with large vessel and single coronary artery lesion. | Clinical cardiology 20100601 |
| A randomised comparison of novolimus-eluting and zotarolimus-eluting coronary stents: 9-month follow-up results of the EXCELLA II study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601 |
| The twelve-month outcomes of a biolimus eluting stent with a biodegradable polymer compared with a sirolimus eluting stent with a durable polymer. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601 |
| Coronary angioscopic findings eight months after sirolimus-eluting stent implantation: a comparison between ST-elevation myocardial infarction and stable angina pectoris. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100601 |
| Risk of diarrhoea in a long-term cohort of renal transplant patients given mycophenolate mofetil: the significant role of the UGT1A8 2 variant allele. | British journal of clinical pharmacology 20100601 |
| Targeting multiple angiogenic pathways for the treatment of neuroblastoma. | Journal of pediatric surgery 20100601 |
| Comparison of the safety and efficacy of cyclosporine minimization versus cyclosporine elimination in de novo renal allograft patients receiving sirolimus. | Transplantation proceedings 20100601 |
| Rapamycin promotes the expansion of CD4(+) Foxp3(+) regulatory T cells after liver transplantation. | Transplantation proceedings 20100601 |
| Relationship between everolimus blood concentration assessed using the Innofluor Certican Fluorescence Polarization Immunoassay and the Architect i System sirolimus chemiluminescent microparticle immunoassay. | Transplantation proceedings 20100601 |
| Rapamycin inhibits activator protein-1 but not nuclear factor-kappaB activity of mature bone marrow-derived dendritic cells. | Transplantation proceedings 20100601 |
| Posttransplantation therapeutic rapamycin concentration protects nitric oxide-related vascular endothelial function: comparative effects in rat thoracic aorta and coronary endothelial cell culture. | Transplantation proceedings 20100601 |
| Long-term clinical results following stenting of the left main stem: insights from RESEARCH (Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated at Rotterdam Cardiology Hospital) Registries. | JACC. Cardiovascular interventions 20100601 |
| Strut coverage and vessel wall response to zotarolimus-eluting and bare-metal stents implanted in patients with ST-segment elevation myocardial infarction: the OCTAMI (Optical Coherence Tomography in Acute Myocardial Infarction) Study. | JACC. Cardiovascular interventions 20100601 |
| A status report on drug-associated acne and acneiform eruptions. | Journal of drugs in dermatology : JDD 20100601 |
| The phosphatidylinositol 3-kinase/Akt/mTOR signaling network as a therapeutic target in acute myelogenous leukemia patients. | Oncotarget 20100601 |
| mTOR-mediated activation of p70 S6K induces differentiation of pluripotent human embryonic stem cells. | Cellular reprogramming 20100601 |
| Hyperglycemia induced by tacrolimus and sirolimus is reversible in normal sprague-dawley rats. | Endocrine 20100601 |
| Autism spectrum disorder is related to endoplasmic reticulum stress induced by mutations in the synaptic cell adhesion molecule, CADM1. | Cell death & disease 20100601 |
| Initial experience with an everolimus-eluting, second-generation drug-eluting stent for treatment of intracranial atherosclerosis. | Journal of neurointerventional surgery 20100601 |
| Involvement of heterogeneous ribonucleoprotein F in the regulation of cell proliferation via the mammalian target of rapamycin/S6 kinase 2 pathway. | The Journal of biological chemistry 20100528 |
| mTORC1-mediated cell proliferation, but not cell growth, controlled by the 4E-BPs. | Science (New York, N.Y.) 20100528 |
| Thrombotic microangiopathy after GVHD prophylaxis with tacrolimus/sirolimus: a call for use of consensus definition in reporting. | Blood 20100527 |
| Late airway anastomotic dehiscence associated with sirolimus and migratory staples in a lung transplant recipient. | Transplantation 20100527 |
| Smooth muscle cells orchestrate the endothelial cell response to flow and injury. | Circulation 20100525 |
| Phosphatidic acid is a leukocyte chemoattractant that acts through S6 kinase signaling. | The Journal of biological chemistry 20100521 |
| FOXO3a regulates glycolysis via transcriptional control of tumor suppressor TSC1. | The Journal of biological chemistry 20100521 |
| [18F]Fluorodeoxyglucose positron emission tomography for outcome prediction of mammalian target of rapamycin inhibitor therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100520 |
| Rapamycin and quasi-programmed aging: four years later. | Cell cycle (Georgetown, Tex.) 20100515 |
| Conversion to sirolimus in African American renal allograft recipients undergoing early steroid withdrawal: intermediate-term risks and benefits. | Transplantation 20100515 |
| Long-term vascular changes after drug-eluting stent implantation assessed by serial volumetric intravascular ultrasound analysis. | The American journal of cardiology 20100515 |
| Quality of life in patients with advanced renal cell carcinoma treated with temsirolimus or interferon-alpha. | British journal of cancer 20100511 |
| Single amino-acid changes that confer constitutive activation of mTOR are discovered in human cancer. | Oncogene 20100506 |
| Everolimus-eluting versus paclitaxel-eluting stents in coronary artery disease. | The New England journal of medicine 20100506 |
| Second-generation drug-eluting coronary stents. | The New England journal of medicine 20100506 |
| Mammalian target of rapamycin signaling modulates photic entrainment of the suprachiasmatic circadian clock. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100505 |
| Everolimus and pazopanib: two new drugs for renal cell cancer. | The Medical letter on drugs and therapeutics 20100503 |
| Late stent malapposition risk is higher after drug-eluting stent compared with bare-metal stent implantation and associates with late stent thrombosis. | European heart journal 20100501 |
| mTOR inhibitor RAD001 (Everolimus) enhances the effects of imatinib in chronic myeloid leukemia by raising the nuclear expression of c-ABL protein. | Leukemia research 20100501 |
| Combined treatment with cisplatin and sirolimus to enhance cell death in human mesothelioma. | The Journal of thoracic and cardiovascular surgery 20100501 |
| Sirolimus and everolimus clearance in maintenance kidney and liver transplant recipients: diagnostic efficiency of the concentration/dose ratio for the prediction of trough steady-state concentrations. | Upsala journal of medical sciences 20100501 |
| Effects of the novel protein kinase C inhibitor AEB071 (Sotrastaurin) on rat cardiac allograft survival using single agent treatment or combination therapy with cyclosporine, everolimus or FTY720. | Transplant international : official journal of the European Society for Organ Transplantation 20100501 |
| Identification of functional FKB protein in Echinococcus granulosus: its involvement in the protoscolicidal action of rapamycin derivates and in calcium homeostasis. | International journal for parasitology 20100501 |
| Intrarenal vascular resistance parameters in kidney transplant patients receiving calcineurin inhibitor-based or sirolimus-based regimens. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501 |
| Anaemia, microcytosis and sirolimus--is iron the missing link? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100501 |
| Methylglyoxal activates Gcn2 to phosphorylate eIF2alpha independently of the TOR pathway in Saccharomyces cerevisiae. | Applied microbiology and biotechnology 20100501 |
| IVUS radiofrequency analysis in the evaluation of the polymeric struts of the bioabsorbable everolimus-eluting device during the bioabsorption process. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100501 |
| Randomized comparison of everolimus- and paclitaxel-eluting stents: pooled analysis of the 2-year clinical follow-up from the SPIRIT II and III trials. | European heart journal 20100501 |
| Mammalian target of rapamycin regulates vascular endothelial growth factor-dependent liver cyst growth in polycystin-2-defective mice. | Hepatology (Baltimore, Md.) 20100501 |
| Histology of highly echolucent regions in optical coherence tomography images from two patients with sirolimus-eluting stent restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100501 |
| Sirolimus versus paclitaxel-eluting stents in small coronary vessels: long-term outcomes from a single-center registry. | Journal of cardiovascular medicine (Hagerstown, Md.) 20100501 |
| Regulation of the autophagic machinery in human neutrophils. | European journal of immunology 20100501 |
| Therapies for the medical management of persistent hypoglycaemia in two cases of inoperable malignant insulinoma. | European journal of endocrinology 20100501 |
| The treatment of recurrent/refractory chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL) with everolimus results in clinical responses and mobilization of CLL cells into the circulation. | Cancer 20100501 |
| Delayed re-endothelialization with rapamycin-coated stents is rescued by the addition of a glycogen synthase kinase-3beta inhibitor. | Cardiovascular research 20100501 |
| In vitro and in vivo performance of a dual drug-eluting stent (DDES). | Biomaterials 20100501 |
| Exendin-4 protects pancreatic beta cells from the cytotoxic effect of rapamycin by inhibiting JNK and p38 phosphorylation. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20100501 |
| Indications, tolerance and complications of a sirolimus and calcineurin inhibitor immunosuppression regimen: intermediate experience in pediatric heart transplantation recipients. | Pediatric transplantation 20100501 |
| Treatment with the mTOR inhibitor temsirolimus in patients with malignant PEComa. | Annals of oncology : official journal of the European Society for Medical Oncology 20100501 |
| Comparison by optical coherence tomography of paclitaxel-eluting stents with sirolimus-eluting stents implanted in one coronary artery in one procedure. - 6-month follow-up -. | Circulation journal : official journal of the Japanese Circulation Society 20100501 |
| Natural products in structure-assisted design of molecular cancer therapeutics. | Current pharmaceutical design 20100501 |
| A Phase II trial of the oral mTOR inhibitor everolimus in relapsed Hodgkin lymphoma. | American journal of hematology 20100501 |
| MCF-7 breast cancer cells selected for tamoxifen resistance acquire new phenotypes differing in DNA content, phospho-HER2 and PAX2 expression, and rapamycin sensitivity. | Cancer biology & therapy 20100501 |
| Papillary renal cell carcinoma with cutaneous metastases. | The American journal of the medical sciences 20100501 |
| Impact of angiographic and intravascular ultrasound features on clinical outcome after sirolimus-eluting stent implantation for de-novo lesions in nondiabetic and type 2 diabetic patients. | Coronary artery disease 20100501 |
| Transforming growth factor beta 1 (TGF-beta1) and rapamycin synergize to effectively suppress human T cell responses via upregulation of FoxP3+ Tregs. | Transplant immunology 20100501 |
| Giant warts in a kidney transplant patient: regression with sirolimus. | The British journal of dermatology 20100501 |
| Personalized molecular targeted therapy in advanced, recurrent hepatocellular carcinoma after liver transplantation: a proof of principle. | Journal of hepatology 20100501 |
| Predictor of subsequent target lesion revascularization in patients with drug-eluting stent restenosis undergoing percutaneous coronary intervention. | Journal of cardiology 20100501 |
| Rapamycin extends maximal lifespan in cancer-prone mice. | The American journal of pathology 20100501 |
| How to interpret phase II data for everolimus plus bevacizumab in renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501 |
| Phase II trial of bevacizumab and everolimus in patients with advanced renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100501 |
| The initial extent of malapposition in ST-elevation myocardial infarction treated with drug-eluting stent: the usefulness of optical coherence tomography. | Yonsei medical journal 20100501 |
| Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease. | Nature neuroscience 20100501 |
| Mutant protein kinase C gamma that causes spinocerebellar ataxia type 14 (SCA14) is selectively degraded by autophagy. | Genes to cells : devoted to molecular & cellular mechanisms 20100501 |
| A functional link between polo-like kinase 1 and the mammalian target-of-rapamycin pathway? | Cell cycle (Georgetown, Tex.) 20100501 |
| Preferential increase in memory and regulatory subsets during T-lymphocyte immune reconstitution after Thymoglobulin induction therapy with maintenance sirolimus vs cyclosporine. | Transplant immunology 20100501 |
| Calcineurin inhibitor-related cholestasis complicating lung transplantation. | The Annals of thoracic surgery 20100501 |
| Novel immunosuppressive agents in kidney transplantation. | Clinical nephrology 20100501 |
| Addition of induction therapy offsets the hazard of marked calcineurin minimization among renal transplant recipients treated with sirolimus. | Clinical nephrology 20100501 |
| True comparison of different stents in the same coronary artery. | Circulation journal : official journal of the Japanese Circulation Society 20100501 |
| Vascular response to overlapping everolimus-eluting stents. - Comparison with paclitaxel-eluting stents -. | Circulation journal : official journal of the Japanese Circulation Society 20100501 |
| Everolimus in relapsed Hodgkin's lymphoma: something exciting or a case of caveat mTOR? | American journal of hematology 20100501 |
| High incidence of thrombus formation at 18 months after paclitaxel-eluting stent implantation: angioscopic comparison with sirolimus-eluting stent. | American heart journal 20100501 |
| Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy. | Cell cycle (Georgetown, Tex.) 20100501 |
| Long-interval T2-weighted subtraction magnetic resonance imaging: a powerful new outcome measure in multiple sclerosis trials. | Annals of neurology 20100501 |
| Longer-term outcomes of paclitaxel stent implantation as an initial treatment strategy for sirolimus-eluting stent restenosis. | The Journal of invasive cardiology 20100501 |
| Sirolimus and tuberous sclerosis-associated renal angiomyolipomas. | Archives of disease in childhood 20100501 |
| [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. | Aktuelle Urologie 20100501 |
| [Gingival hyperplasia secondary to everolimus therapy]. | Actas dermo-sifiliograficas 20100501 |
| Paclitaxel- versus sirolimus-eluting stents for treatment of ST-segment elevation myocardial infarction: with analyses for diabetic and nondiabetic subpopulation. | JACC. Cardiovascular interventions 20100501 |
| Optical coherence tomography assessment of in vivo vascular response after implantation of overlapping bare-metal and drug-eluting stents. | JACC. Cardiovascular interventions 20100501 |
| 10-year follow-up of the first Cypher stent implanted in human: an invasive evaluation with angiography, intravascular ultrasound, and optical coherence tomography. | JACC. Cardiovascular interventions 20100501 |
| Calorie restriction: what recent results suggest for the future of ageing research. | European journal of clinical investigation 20100501 |
| Immunosuppressive agents and bone disease in renal transplant patients with hypercalcemia. | Transplantation proceedings 20100501 |
| De novo everolimus-based therapy in renal transplant recipients: effect on proteinuria and renal prognosis. | Transplantation proceedings 20100501 |
| Once-a-day administration of everolimus, cyclosporine, and steroid after renal transplantation: a review of the rationale. | Transplantation proceedings 20100501 |
| Once daily everolimus is safe and effective in de novo renal transplant recipients: six-month results of a pilot study. | Transplantation proceedings 20100501 |
| Conversion of stable kidney transplant recipients from a twice-daily to once-daily everolimus regimen. | Transplantation proceedings 20100501 |
| Conversion to rapamycin immunosuppression for malignancy after kidney transplantation. | Transplantation proceedings 20100501 |
| Effects of sirolimus on human mesangial cells. | Transplantation proceedings 20100501 |
| Liver transplantation due to iatrogenic injuries: two case reports. | Transplantation proceedings 20100501 |
| Liver resection associated with mini porto-caval shunt as salvage treatment in patients with progression of hepatocellular carcinoma before liver transplantation: a case report. | Transplantation proceedings 20100501 |
| Lower homocysteine levels in renal transplant recipients treated with everolimus: a possible link with a decreased cardiovascular risk? | Transplantation proceedings 20100501 |
| Eighteen-month clinical safety and efficacy outcomes of sirolimus-, paclitaxel- and zotarolimus-drug eluting stents in diabetic patients undergoing percutaneous coronary intervention for complex coronary artery stenosis. | Annals of the Academy of Medicine, Singapore 20100501 |
| The role of mTOR in memory CD8 T-cell differentiation. | Immunological reviews 20100501 |
| A randomised comparison between everolimus-eluting stent and sirolimus-eluting stent in chronic coronary total occlusions. Rationale and design of the CIBELES (non-acute Coronary occlusion treated by EveroLimus-Eluting Stent) trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100501 |
| Endothelial function rather than endothelial restoration is altered in paclitaxel- as compared to bare metal-, sirolimusand tacrolimus-eluting stents. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100501 |
| Neuroendocrine gastroenteropancreatic tumours: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. | Annals of oncology : official journal of the European Society for Medical Oncology 20100501 |
| Present state of target therapy for disseminated renal cell carcinoma. | Immunotherapy 20100501 |
| Regulation of survivin by PI3K/Akt/p70S6K1 pathway. | Biochemical and biophysical research communications 20100430 |
| mTOR inhibitor rapamycin alone or combined with cisplatin inhibits growth of esophageal squamous cell carcinoma in nude mice. | Cancer letters 20100428 |
| Impact of immunosuppressants on the therapeutic efficacy of in vitro-expanded CD4+CD25+Foxp3+ regulatory T cells in allotransplantation. | Transplantation 20100427 |
| Interaction between everolimus and tacrolimus in renal transplant recipients: a pharmacokinetic controlled trial. | Transplantation 20100427 |
| Molecular interplay between mammalian target of rapamycin (mTOR), amyloid-beta, and Tau: effects on cognitive impairments. | The Journal of biological chemistry 20100423 |
| Sirolimus- versus paclitaxel-eluting stents for the treatment of coronary bifurcations results: from the COBIS (Coronary Bifurcation Stenting) Registry. | Journal of the American College of Cardiology 20100420 |
| Rapamycin regulates endothelial cell migration through regulation of the cyclin-dependent kinase inhibitor p27Kip1. | The Journal of biological chemistry 20100416 |
| Ribosomal protein S6 kinase is a critical downstream effector of the target of rapamycin complex 1 for long-term facilitation in Aplysia. | The Journal of biological chemistry 20100416 |
| Long-term follow-up of patients with sirolimus-eluting stents for treatment of bare-metal in-stent restenosis. | International journal of cardiology 20100415 |
| Long-term outcome after drug eluting stenting in patients with ST-segment elevation myocardial infarction: data from the REAL registry. | International journal of cardiology 20100415 |
| Everolimus with reduced calcineurin inhibitor in thoracic transplant recipients with renal dysfunction: a multicenter, randomized trial. | Transplantation 20100415 |
| Sensitive quantification of sirolimus and everolimus by LC-MS/MS with online sample cleanup. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100415 |
| Comparison by meta-analysis of drug-eluting stents and bare metal stents for saphenous vein graft intervention. | The American journal of cardiology 20100415 |
| Multicenter phase II study of everolimus in patients with previously treated metastatic gastric cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100410 |
| Late and very late stent thrombosis after polymer-based sirolimus- or paclitaxel-eluting stent implantation in real-world clinical practice. | Chinese medical journal 20100405 |
| Gender difference in patients with acute myocardial infarction treated by primary percutaneous coronary intervention in drug-eluting stent era. | Chinese medical journal 20100405 |
| Absence of gender disparity in short-term clinical outcomes in patients with acute ST-segment elevation myocardial infarction undergoing sirolimus-eluting stent based primary coronary intervention: a report from Shanghai Acute Coronary Event (SACE) Registry. | Chinese medical journal 20100405 |
| Comparison of long-term clinical outcome after successful implantation of Firebird sirolimus- and Taxus paclitaxel-eluting stents in Chinese population: analysis of a large single center registry. | Chinese medical journal 20100405 |
| CD4+Foxp3+ regulatory T cells converted by rapamycin from peripheral CD4+CD25(-) naive T cells display more potent regulatory ability in vitro. | Chinese medical journal 20100405 |
| Everolimus-eluting versus paclitaxel-eluting stents. | Lancet (London, England) 20100403 |
| Everolimus-eluting versus paclitaxel-eluting stents. | Lancet (London, England) 20100403 |
| The autophagy-lysosome pathway: a novel mechanism involved in the processing of oxidized LDL in human vascular endothelial cells. | Biochemical and biophysical research communications 20100402 |
| Treatment of vertebral artery origin stenosis with anti-proliferative drug-eluting stents. | Journal of neuroimaging : official journal of the American Society of Neuroimaging 20100401 |
| Fracture of a paclitaxol-eluting stent implanted for in-stent restenosis at the site of sirolimus-eluting stent fracture. | International journal of cardiology 20100401 |
| Death caused by simultaneous subacute stent thrombosis of sirolimus-eluting stents in left anterior descending artery and left circumflex artery. | International journal of cardiology 20100401 |
| Rapamycin inhibits proliferation and migration of hepatoma cells in vitro. | The Journal of surgical research 20100401 |
| Rapamycin promotes the osteoblastic differentiation of human embryonic stem cells by blocking the mTOR pathway and stimulating the BMP/Smad pathway. | Stem cells and development 20100401 |
| Involvement of mTOR and survivin inhibition in tamoxifen-induced apoptosis in human hepatoblastoma cell line HepG2. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100401 |
| Increase in proteinuria >200 mg/g after late rejection is associated with poor graft survival. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100401 |
| Impact of Cyclin B2 and Cell division cycle 2 on tubular hyperplasia in progressive chronic renal failure rats. | American journal of physiology. Renal physiology 20100401 |
| Tuberous sclerosis complex: a brave new world? | Current opinion in neurology 20100401 |
| A clinical and angiographic study of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with multivessel coronary artery disease. Study design and rationale of the EXECUTIVE trial. | Journal of cardiovascular medicine (Hagerstown, Md.) 20100401 |
| Activation of mTOR signaling pathway contributes to survival of cervical cancer cells. | Gynecologic oncology 20100401 |
| Targeting of VEGF-dependent transendothelial migration of cancer cells by bevacizumab. | Molecular oncology 20100401 |
| Inhibition of target of rapamycin signaling and stress activate autophagy in Chlamydomonas reinhardtii. | Plant physiology 20100401 |
| Implication of RICTOR in the mTOR inhibitor-mediated induction of insulin-like growth factor-I receptor (IGF-IR) and human epidermal growth factor receptor-2 (Her2) expression in gastrointestinal cancer cells. | Biochimica et biophysica acta 20100401 |
| In vitro interaction of posaconazole with calcineurin inhibitors and sirolimus against zygomycetes. | The Journal of antimicrobial chemotherapy 20100401 |
| Inhibition of glycolysis enhances cisplatin-induced apoptosis in ovarian cancer cells. | American journal of obstetrics and gynecology 20100401 |
| A 3-year clinical outcome after percutaneous coronary intervention using sirolimus-eluting stent and off-pump coronary artery bypass grafting for the treatment of diabetic patients with multivessel disease. | Circulation journal : official journal of the Japanese Circulation Society 20100401 |
| Treating triple-negative breast cancer by a combination of rapamycin and cyclophosphamide: an in vivo bioluminescence imaging study. | European journal of cancer (Oxford, England : 1990) 20100401 |
| Activation of autophagy and Akt/CREB signaling play an equivalent role in the neuroprotective effect of rapamycin in neonatal hypoxia-ischemia. | Autophagy 20100401 |
| Sirolimus-based immunosuppression is associated with increased survival after liver transplantation for hepatocellular carcinoma. | Hepatology (Baltimore, Md.) 20100401 |
| 4-Substituted-7-azaindoles bearing a ureidobenzofuranone moiety as potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR). | Bioorganic & medicinal chemistry letters 20100401 |
| New drug-eluting stent concepts. | Nature reviews. Cardiology 20100401 |
| Long-term clinical outcome of chronic total occlusive lesions treated with drug-eluting stents: comparison of sirolimus-eluting and paclitaxel-eluting stents. | Circulation journal : official journal of the Japanese Circulation Society 20100401 |
| RAD001 offers a therapeutic intervention through inhibition of mTOR as a potential strategy for esophageal cancer. | Oncology reports 20100401 |
| Relevance of the mTOR signaling pathway in the pathophysiology of splenomegaly in rats with chronic portal hypertension. | Journal of hepatology 20100401 |
| mTOR signaling and drug development in cancer. | Nature reviews. Clinical oncology 20100401 |
| Real world, long-term outcomes comparison between paclitaxel-eluting and sirolimus-eluting stent platforms. | Journal of interventional cardiology 20100401 |
| Two-year clinical registry follow-up of endothelial progenitor cell capture stent versus sirolimus-eluting bioabsorbable polymer-coated stent versus bare metal stents in patients undergoing primary percutaneous coronary intervention for ST elevation myocardial infarction. | Journal of interventional cardiology 20100401 |
| Role of N-end rule ubiquitin ligases UBR1 and UBR2 in regulating the leucine-mTOR signaling pathway. | Genes to cells : devoted to molecular & cellular mechanisms 20100401 |
| FDA approval summary: temsirolimus as treatment for advanced renal cell carcinoma. | The oncologist 20100401 |
| Periadventitial rapamycin-eluting microbeads promote vein graft disease in long-term pig vein-into-artery interposition grafts. | Circulation. Cardiovascular interventions 20100401 |
| In-hospital and 12-month postprocedural clinical outcome of coronary bifurcational lesion treatment with the endeavor stent. | Journal of interventional cardiology 20100401 |
| Drug-eluting stents versus bare-metal stents in acute ST-segment elevation myocardial infarction. a single-center experience with long-term follow up. | The Journal of invasive cardiology 20100401 |
| Drug-eluting stent versus bare-metal stent in acute ST-segment elevation myocardial infarction: a word of caution. | The Journal of invasive cardiology 20100401 |
| Percutaneous interventions below the knee in patients with critical limb ischemia using drug eluting stents. | The Journal of cardiovascular surgery 20100401 |
| Drug eluting stents versus PTA with GP IIb/IIIa blockade below the knee in patients with current ulcers--The BELOW Study. | The Journal of cardiovascular surgery 20100401 |
| Missing data in repeated measures study. | Heart (British Cardiac Society) 20100401 |
| Increased restenosis rates 12 months after coronary implantation of the sirolimus-eluting YUKON-choice stent compared to the paclitaxel-eluting TAXUS Stent. | Clinical cardiology 20100401 |
| Thrombus in sirolimus-eluting stent identified by optical coherence tomography. | Clinical cardiology 20100401 |
| Palliative chemotherapy for pancreatic malignancies. | The Surgical clinics of North America 20100401 |
| Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma. | Molecular cancer therapeutics 20100401 |
| Evaluation of a rapamycin-regulated serotype 2 adeno-associated viral vector in macaque parotid glands. | Oral diseases 20100401 |
| Sirolimus- versus paclitaxel-eluting stents for the treatment of cardiac allograft vasculopathy. | JACC. Cardiovascular interventions 20100401 |
| Monitoring in vivo absorption of a drug-eluting bioabsorbable stent with intravascular ultrasound-derived parameters a feasibility study. | JACC. Cardiovascular interventions 20100401 |
| Catheter-induced stent occlusion: uncommon complication during diagnostic angiography. | JACC. Cardiovascular interventions 20100401 |
| Polymer-free biolimus a9-coated stent demonstrates more sustained intimal inhibition, improved healing, and reduced inflammation compared with a polymer-coated sirolimus-eluting cypher stent in a porcine model. | Circulation. Cardiovascular interventions 20100401 |
| A case of lipid core plaque progression and rupture at the edge of a coronary stent: elucidating the mechanisms of drug-eluting stent failure. | Circulation. Cardiovascular interventions 20100401 |
| [Effect of rapamycin on apoptosis in human myelodysplastic syndrome cell line MUTZ-1 and its possible mechanisms]. | Zhongguo shi yan xue ye xue za zhi 20100401 |
| Can cyclosporine blood level be reduced to half after heart transplantation? | Transplantation proceedings 20100401 |
| Combined sirolimus-calcineurin inhibitor immunosuppressive therapy in simultaneous heart and kidney transplantation: a retrospective analysis of a single hospital's experience. | Transplantation proceedings 20100401 |
| The survival of heart transplant recipients using cyclosporine and everolimus is not inferior to that using cyclosporine and mycophenolate. | Transplantation proceedings 20100401 |
| Sunitinib, sorafenib, temsirolimus or bevacizumab in the treatment of metastatic renal cell carcinoma: a review of health economic evaluations. | Journal of chemotherapy (Florence, Italy) 20100401 |
| [Mammalian target of rapamycin inhibitors for the targeted therapy of non-small cell lung cancer]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20100401 |
| [Neuroendocrine carcinoma of the lung: a diagnostic and therapeutic challenge]. | Medizinische Klinik (Munich, Germany : 1983) 20100401 |
| Effect and mechanism of panaxoside Rg1 on neovascularization in myocardial infarction rats. | Chinese journal of integrative medicine 20100401 |
| Stem cell marker upregulation in normal cutaneous vessels following pulsed-dye laser exposure and its abrogation by concurrent rapamycin administration: implications for treatment of port-wine stain birthmarks. | Journal of cutaneous pathology 20100401 |
| [Everolimus (RAD001/Afinitor) in the treatment of metastatic cell carcinoma]. | Revue medicale de Liege 20100401 |
| Paclitaxel and sirolimus eluting stents versus bare metal stents: long-term risk of stent thrombosis and other outcomes. From the Western Denmark Heart Registry. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401 |
| In vivo evaluation of stent strut distribution patterns in the bioabsorbable everolimus-eluting device: an OCT ad hoc analysis of the revision 1.0 and revision 1.1 stent design in the ABSORB clinical trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401 |
| Short- and long-term health related quality-of-life and anginal status of the Arterial Revascularisation Therapies Study part II, ARTS-II; sirolimus-eluting stents for the treatment of patients with multivessel coronary artery disease. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100401 |
| Identification of annexin A13 as a regulator of chemotherapy resistance using random homozygous gene perturbation. | Analytical and quantitative cytology and histology 20100401 |
| [Effect of sirolimus on capacity of splenic dendritic cells from traumatized mice in inducing T cell responses ex vivo]. | Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20100401 |
| Rapamycin inhibits relapsing experimental autoimmune encephalomyelitis by both effector and regulatory T cells modulation. | Journal of neuroimmunology 20100330 |
| First report on a series of HIV patients undergoing rapamycin monotherapy after liver transplantation. | Transplantation 20100327 |
| Comparing an early corticosteroid/late calcineurin-free immunosuppression protocol to a sirolimus-, cyclosporine A-, and prednisone-based regimen for pancreas-kidney transplantation. | Transplantation 20100327 |
| Efficacy and safety of zotarolimus-eluting and sirolimus-eluting coronary stents in routine clinical care (SORT OUT III): a randomised controlled superiority trial. | Lancet (London, England) 20100327 |
| Sorting out drug-eluting stents. | Lancet (London, England) 20100327 |
| Bafilomycins produced in culture by Streptomyces spp. isolated from marine habitats are potent inhibitors of autophagy. | Journal of natural products 20100326 |
| Letter by Virmani et al regarding article, 'Drug-eluting stents in animals and patients: where do we stand today?'. | Circulation 20100323 |
| An expeditious route to fluorinated rapamycin analogues by utilising mutasynthesis. | Chembiochem : a European journal of chemical biology 20100322 |
| Lesion complexity determines arterial drug distribution after local drug delivery. | Journal of controlled release : official journal of the Controlled Release Society 20100319 |
| Glycolysis inhibition sensitizes tumor cells to death receptors-induced apoptosis by AMP kinase activation leading to Mcl-1 block in translation. | Oncogene 20100318 |
| TSC1 loss synergizes with KRAS activation in lung cancer development in the mouse and confers rapamycin sensitivity. | Oncogene 20100318 |
| 5-year clinical outcomes of the ARTS II (Arterial Revascularization Therapies Study II) of the sirolimus-eluting stent in the treatment of patients with multivessel de novo coronary artery lesions. | Journal of the American College of Cardiology 20100316 |
| Immunosuppressant neurotoxicity in rat brain models: oxidative stress and cellular metabolism. | Chemical research in toxicology 20100315 |
| Comparison of outcomes between Zotarolimus- and sirolimus-eluting stents in patients with ST-segment elevation acute myocardial infarction. | The American journal of cardiology 20100315 |
| Rapamycin for Kaposi's sarcoma and graft-versus-host disease in bone marrow transplant recipient. | Transplantation 20100315 |
| Pregnancy restores the regenerative capacity of the aged liver via activation of an mTORC1-controlled hyperplasia/hypertrophy switch. | Genes & development 20100315 |
| mTOR Ser-2481 autophosphorylation monitors mTORC-specific catalytic activity and clarifies rapamycin mechanism of action. | The Journal of biological chemistry 20100312 |
| Rapamycin inhibits oncogenic intestinal ion channels and neoplasia in APC(Min/+) mice. | Oncogene 20100311 |
| Stem-cell transplantation for sickle cell disease. | The New England journal of medicine 20100311 |
| Phase II trial of the oral mammalian target of rapamycin inhibitor everolimus in relapsed or refractory Waldenstrom macroglobulinemia. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100310 |
| Nocardiopsins: new FKBP12-binding macrolide polyketides from an Australian marine-derived actinomycete, Nocardiopsis sp. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100308 |
| Neuroendocrine tumors of the pancreas: what's new. Highlights from the '2010 ASCO Gastrointestinal Cancers Symposium'. Orlando, FL, USA. January 22-24, 2010. | JOP : Journal of the pancreas 20100305 |
| Liquid chromatography-tandem mass spectrometry method for determination of Sirolimus coated drug eluting nano porous carbon stents. | Biomedical chromatography : BMC 20100301 |
| Rapamycin potentiates the effects of paclitaxel in endometrial cancer cells through inhibition of cell proliferation and induction of apoptosis. | International journal of cancer 20100301 |
| Comparative pharmacokinetics of RAD001 (everolimus) in normal and tumor-bearing rodents. | Cancer chemotherapy and pharmacology 20100301 |
| Increased frequency of regulatory T cells and selection of highly potent CD62L+ cells during treatment of human lung transplant recipients with rapamycin. | Transplant international : official journal of the European Society for Organ Transplantation 20100301 |
| Sirolimus monotherapy as maintenance immunosuppression: a multicenter experience. | Transplant international : official journal of the European Society for Organ Transplantation 20100301 |
| Rapamycin (sirolimus) in tuberous sclerosis associated pediatric central nervous system tumors. | Pediatric blood & cancer 20100301 |
| Rapamycin, unlike cyclosporine A, enhances suppressive functions of in vitro-induced CD4+CD25+ Tregs. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100301 |
| Autophagy is involved in starvation response and cell death in Blastocystis. | Microbiology (Reading, England) 20100301 |
| [Impact of immunotherapy in metastatic kidney cancer in Germany after introduction of new target therapy--results of a telephone survey of the German Society of Immuno- and Targeted Therapy (DGFIT)]. | Aktuelle Urologie 20100301 |
| Rapamycin and the transcription factor C/EBPbeta as a switch in osteoclast differentiation: implications for lytic bone diseases. | Journal of molecular medicine (Berlin, Germany) 20100301 |
| Sirolimus and cyclosporine A alter barrier function in renal proximal tubular cells through stimulation of ERK1/2 signaling and claudin-1 expression. | American journal of physiology. Renal physiology 20100301 |
| Dissecting the role of mTOR: lessons from mTOR inhibitors. | Biochimica et biophysica acta 20100301 |
| Cytocidal amino acid starvation of Saccharomyces cerevisiae and Candida albicans acetolactate synthase (ilv2{Delta}) mutants is influenced by the carbon source and rapamycin. | Microbiology (Reading, England) 20100301 |
| Rapamycin ameliorates PKD resulting from conditional inactivation of Pkd1. | Journal of the American Society of Nephrology : JASN 20100301 |
| AZD6244 (ARRY-142886) enhances the antitumor activity of rapamycin in mouse models of human hepatocellular carcinoma. | Cancer 20100301 |
| The release kinetics of drug eluting stents containing sirolimus as coated drug: role of release media. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20100301 |
| Fission yeast TORC1 regulates phosphorylation of ribosomal S6 proteins in response to nutrients and its activity is inhibited by rapamycin. | Journal of cell science 20100301 |
| Bioequivalence testing of immunosuppressants: concepts and misconceptions. | Kidney international. Supplement 20100301 |
| Effects of aging and gender on muscle mass and regulation of Akt-mTOR-p70s6k related signaling in the F344BN rat model. | Mechanisms of ageing and development 20100301 |
| Simulation of sirolimus exposures and population variability immediately post renal transplantation: importance of the patient's CYP3A5 genotype in tailoring treatment. | Biopharmaceutics & drug disposition 20100301 |
| Protection from rapamycin-induced apoptosis by insulin-like growth factor-I is partially dependent on protein kinase C signaling. | Cancer research 20100301 |
| Everolimus. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100301 |
| Recent advances and future directions in the management of metastatic renal cell carcinoma. | Anti-cancer agents in medicinal chemistry 20100301 |
| Restenosis rates following vertebral artery origin stenting: does stent type make a difference? | The Journal of invasive cardiology 20100301 |
| Conversion of cyclosporine to sirolimus before 12 months is associated with marked improvement in renal function and low proteinuria in a South African renal transplant population. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20100301 |
| [Recent progress in the molecular-targeting treatment of neuroendocrine tumors]. | Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20100301 |
| Molecular basis of different outcomes for drug-eluting stents that release sirolimus or tacrolimus. | Current opinion in drug discovery & development 20100301 |
| Treatment of non-left main bifurcation lesions using the sirolimus-eluting stent: A comparison of chronic outcomes of cross-over single stenting and crush stenting. | Journal of cardiology 20100301 |
| Rapamycin and tacrolimus differentially modulate acute graft-versus-host disease in rats after liver transplantation. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100301 |
| Does 'late catch-up' exist in drug-eluting stents: insights from a serial quantitative coronary angiography analysis of sirolimus versus paclitaxel-eluting stents. | American heart journal 20100301 |
| Long-term outcome of percutaneous catheter intervention for de novo coronary bifurcation lesions with drug-eluting stents or bare-metal stents. | American heart journal 20100301 |
| Everolimus (RAD001) in the treatment of advanced renal cell carcinoma: a review. | The oncologist 20100301 |
| Treatment strategies and clinical trial design in ADPKD. | Advances in chronic kidney disease 20100301 |
| Predictive value of C-reactive protein after drug-eluting stent implantation. | Future cardiology 20100301 |
| Use of tacrolimus and the development of posttransplant diabetes mellitus: a Brazilian single-center, observational study. | Transplantation proceedings 20100301 |
| Recovery of renal function in heart transplantation patients after conversion from a calcineurin inhibitor-based therapy to sirolimus. | Transplantation proceedings 20100301 |
| Cell phenotype evaluation at various sites after skin transplantation and FTY720 plus sirolimus therapy. | Transplantation proceedings 20100301 |
| Sirolimus in combination with FTY720: analysis of urinary and serum parameters. | Transplantation proceedings 20100301 |
| Rescue immunosuppression with mammalian target of rapamycin inhibitor drugs in liver transplantation. | Transplantation proceedings 20100301 |
| mTOR signaling: a central pathway to pathogenesis in systemic lupus erythematosus? | Discovery medicine 20100301 |
| Long-term clinical outcomes after sirolimus-eluting stent implantation in dialysis patients. | International heart journal 20100301 |
| Rapamycin-mediated FOXO1 inactivation reduces the anticancer efficacy of rapamycin. | Anticancer research 20100301 |
| [Recent advance in tuberous sclerosis-related genes and their expression]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20100301 |
| [Vessel response evaluation by optical coherence tomography after drug-eluting stent implantation in the left main coronary artery]. | Giornale italiano di cardiologia (2006) 20100301 |
| Sirolimus-induced severe hypertriglyceridemia in a lung transplant recipient. | Transplantation 20100227 |
| StatBite: FDA oncology drug product approvals in 2009. | Journal of the National Cancer Institute 20100224 |
| Maintenance of long-term clinical benefit with sirolimus-eluting stents in patients with ST-segment elevation myocardial infarction 3-year results of the SESAMI (sirolimus-eluting stent versus bare-metal stent in acute myocardial infarction) trial. | Journal of the American College of Cardiology 20100223 |
| Constitutively active AKT depletes hematopoietic stem cells and induces leukemia in mice. | Blood 20100218 |
| Rapid inactivation of proteins by rapamycin-induced rerouting to mitochondria. | Developmental cell 20100216 |
| Long-term effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis results of the TRUE (Tuscany Registry of sirolimus for unselected in-stent restenosis) registry at 4 years. | Journal of the American College of Cardiology 20100216 |
| Three-year outcome of drug-eluting stent implantation for coronary artery bifurcation lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215 |
| Comparison of 2-year clinical outcomes with sirolimus and paclitaxel-eluting stents for patients with diabetes: results of the Registro Regionale AngiopLastiche Emilia-Romagna Registry. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215 |
| Initiation of neuronal differentiation requires PI3-kinase/TOR signalling in the vertebrate neural tube. | Developmental biology 20100215 |
| Systemic rapamycin without loading dose for restenosis prevention after coronary bare metal stent implantation. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215 |
| Noninvasive detection of target modulation following phosphatidylinositol 3-kinase inhibition using hyperpolarized 13C magnetic resonance spectroscopy. | Cancer research 20100215 |
| Supplemental islet infusions restore insulin independence after graft dysfunction in islet transplant recipients. | Transplantation 20100215 |
| The impact of body mass index on the one year outcomes of patients treated by percutaneous coronary intervention with Biolimus- and Sirolimus-eluting stents (from the LEADERS Trial). | The American journal of cardiology 20100215 |
| Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapy. | Proceedings of the American Thoracic Society 20100215 |
| Systemic rapamycin to prevent restenosis: a glimpse to the past? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215 |
| Is diabetes a leveler of efficacy of DES types? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100215 |
| Sirolimus and temsirolimus for epithelioid angiomyolipoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210 |
| Clinical activity of mTOR inhibition with sirolimus in malignant perivascular epithelioid cell tumors: targeting the pathogenic activation of mTORC1 in tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100210 |
| A randomized comparison of the Endeavor zotarolimus-eluting stent versus the TAXUS paclitaxel-eluting stent in de novo native coronary lesions 12-month outcomes from the ENDEAVOR IV trial. | Journal of the American College of Cardiology 20100209 |
| Autophagy impairment inhibits differentiation of glioma stem/progenitor cells. | Brain research 20100208 |
| The rapamycin-derivative RAD001 (everolimus) inhibits cell viability and interacts with the Akt-mTOR-p70S6K pathway in human medullary thyroid carcinoma cells. | Molecular and cellular endocrinology 20100205 |
| p70 S6 kinase limits tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblast-like cells. | Molecular and cellular endocrinology 20100205 |
| Insulin-stimulated interaction with 14-3-3 promotes cytoplasmic localization of lipin-1 in adipocytes. | The Journal of biological chemistry 20100205 |
| Rapamycin enhances the susceptibility of both androgen-dependent and -independent prostate carcinoma cells to docetaxel. | Chinese medical journal 20100205 |
| A phase II pilot study of tacrolimus/sirolimus GVHD prophylaxis for sibling donor hematopoietic stem cell transplantation using 3 conditioning regimens. | Blood 20100204 |
| Steroid avoidance using sirolimus and cyclosporine in pediatric renal transplantation: one year analysis. | Pediatric transplantation 20100201 |
| Cost-effectiveness of immunosuppressive regimens in renal transplant recipients in Germany: a model approach. | The European journal of health economics : HEPAC : health economics in prevention and care 20100201 |
| Rapamycin-insensitive up-regulation of MMP2 and other genes in tuberous sclerosis complex 2-deficient lymphangioleiomyomatosis-like cells. | American journal of respiratory cell and molecular biology 20100201 |
| Metabolic control of antifungal drug resistance. | Fungal genetics and biology : FG & B 20100201 |
| Novel mechanism of rapamycin in GVHD: increase in interstitial regulatory T cells. | Bone marrow transplantation 20100201 |
| Lower incidence of cytomegalovirus infection with everolimus versus mycophenolate mofetil in de novo cardiac transplant recipients: a randomized, multicenter study. | Transplant infectious disease : an official journal of the Transplantation Society 20100201 |
| Rapamycin or tacrolimus alone fails to resist cardiac allograft accelerated rejection mediated by alloreactive CD4(+) memory T cells in mice. | Transplant immunology 20100201 |
| Multicentric outcome analysis of sirolimus-based immunosuppression in 252 liver transplant recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20100201 |
| Improved outcomes using tacrolimus/sirolimus for graft-versus-host disease prophylaxis with a reduced-intensity conditioning regimen for allogeneic hematopoietic cell transplant as treatment of myelofibrosis. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20100201 |
| Treatment of renal artery in-stent restenosis with sirolimus-eluting stents. | Vascular medicine (London, England) 20100201 |
| Rapamycin: the cure for all that ails. | Journal of molecular cell biology 20100201 |
| Clinical and angiographic outcomes with an everolimus-eluting stent in large coronary arteries: the SPIRIT III 4.0 mm registry. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100201 |
| Coronary stenting with the sirolimus-eluting stent in patients with restenosis after intracoronary brachytherapy: results from the prospective multicentre German Cypher Stent Registry. | Clinical research in cardiology : official journal of the German Cardiac Society 20100201 |
| Involvement of mTOR in globular adiponectin-induced generation of reactive oxygen species. | Free radical research 20100201 |
| Bim is the key mediator of glucocorticoid-induced apoptosis and of its potentiation by rapamycin in human myeloma cells. | Biochimica et biophysica acta 20100201 |
| Calcineurin inhibitors affect B cell antibody responses indirectly by interfering with T cell help. | Clinical and experimental immunology 20100201 |
| Rapamycin inhibits lung metastasis of B16 melanoma cells through down-regulating alphav integrin expression and up-regulating apoptosis signaling. | Cancer science 20100201 |
| Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle. | American journal of physiology. Cell physiology 20100201 |
| Tubular toxicity in sirolimus- and cyclosporine-based transplant immunosuppression strategies: an ancillary study from a randomized controlled trial. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20100201 |
| Delayed correlation of mRNA and protein expression in rapamycin-treated cells and a role for Ggc1 in cellular sensitivity to rapamycin. | Molecular & cellular proteomics : MCP 20100201 |
| Quantitative nuclear proteomics identifies mTOR regulation of DNA damage response. | Molecular & cellular proteomics : MCP 20100201 |
| Potential role of everolimus in inducing cholestasis. | Annals of oncology : official journal of the European Society for Medical Oncology 20100201 |
| Effect of everolimus on cell viability in nonfunctioning pituitary adenomas. | The Journal of clinical endocrinology and metabolism 20100201 |
| Coronary stenting with the sirolimus-eluting stent in clinical practice: final results from the prospective multicenter German Cypher Stent Registry. | Journal of interventional cardiology 20100201 |
| Ultra fast liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of cyclosporin A, tacrolimus, sirolimus, and everolimus in whole blood using deuterated internal standards for cyclosporin A and everolimus. | Therapeutic drug monitoring 20100201 |
| RAD 001 (everolimus) prevents mTOR and Akt late re-activation in response to imatinib in chronic myeloid leukemia. | Journal of cellular biochemistry 20100201 |
| Tubular epithelial cell and podocyte apoptosis with de novo sirolimus based immunosuppression in renal allograft recipients with DGF. | Histology and histopathology 20100201 |
| Comparison of neointimal coverage of sirolimus-eluting stents and paclitaxel-eluting stents using optical coherence tomography at 9 months after implantation. | Circulation journal : official journal of the Japanese Circulation Society 20100201 |
| Drug-eluting stent fracture: incidence, contributing factors, and clinical implications. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20100201 |
| MYC activity mitigates response to rapamycin in prostate cancer through 4EBP1-mediated inhibition of autophagy. | Autophagy 20100201 |
| Experience with everolimus (RAD001), an oral mammalian target of rapamycin inhibitor, in patients with systemic mastocytosis. | Leukemia & lymphoma 20100201 |
| Pharmacokinetic sub-study in the SPIRIT III Randomized and Controlled Trial of XIENCE V everolimus eluting coronary stent system. | Journal of interventional cardiology 20100201 |
| Clinical predictors of proteinuria after conversion to sirolimus in kidney transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100201 |
| Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor. | Nature medicine 20100201 |
| A link between mir-100 and FRAP1/mTOR in clear cell ovarian cancer. | Molecular endocrinology (Baltimore, Md.) 20100201 |
| Broadening the therapeutic scope for rapamycin treatment. | Autophagy 20100201 |
| New Drugs2010, PART 1. | Nursing 20100201 |
| Resveratrol and rapamycin: are they anti-aging drugs? | BioEssays : news and reviews in molecular, cellular and developmental biology 20100201 |
| Surgical biology for the clinician: vascular effects of immunosuppression. | Canadian journal of surgery. Journal canadien de chirurgie 20100201 |
| Major adverse cardiac events in patients with moderate to severe renal insufficiency treated with first-generation drug-eluting stents. | The American journal of cardiology 20100201 |
| Augmentation of autophagy by mTOR-inhibition in myocardial infarction: When size matters. | Autophagy 20100201 |
| Rapamycin inhibits cholangiocyte regeneration by blocking interleukin-6-induced activation of signal transducer and activator of transcription 3 after liver transplantation. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20100201 |
| Rapid improvement of nephrogenic systemic fibrosis with rapamycin therapy: possible role of phospho-70-ribosomal-S6 kinase. | Journal of the American Academy of Dermatology 20100201 |
| Why do patients develop proteinuria with sirolimus? Do we have the answer? | American journal of kidney diseases : the official journal of the National Kidney Foundation 20100201 |
| Paclitaxel-eluting versus sirolimus-eluting stents in diabetes mellitus: a report from the National Heart, Lung, and Blood Institute Dynamic Registry. | Circulation. Cardiovascular interventions 20100201 |
| Dependence on phosphoinositide 3-kinase and RAS-RAF pathways drive the activity of RAF265, a novel RAF/VEGFR2 inhibitor, and RAD001 (Everolimus) in combination. | Molecular cancer therapeutics 20100201 |
| Outcomes of unselected recipients of sirolimus-eluting stents: the Cypher stent U.S. post-marketing surveillance registry. | The Journal of invasive cardiology 20100201 |
| Outcomes of overlapping bare-metal stents with sirolimus-eluting stents for long lesions in small coronary vessels. | The Journal of invasive cardiology 20100201 |
| Diffuse alveolar hemorrhage induced by everolimus. | Chest 20100201 |
| Sotrastaurin and everolimus pharmacokinetics after single-dose coadministration. | International journal of clinical pharmacology and therapeutics 20100201 |
| A pooled gender based analysis comparing the XIENCE V(R) everolimus-eluting stent and the TAXUS paclitaxel-eluting stent in male and female patients with coronary artery disease, results of the SPIRIT II and SPIRIT III studies: two-year analysis. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201 |
| Cost-effectiveness of the Endeavor stent in de novo native coronary artery lesions updated with contemporary data. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201 |
| A comparison of clinical presentations, angiographic patterns and outcomes of in-stent restenosis between bare metal stents and drug eluting stents. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201 |
| Effect of drug-eluting stents in patients with acute ST-segment elevation myocardial infarction undergoing percutaneous coronary intervention: a meta-analysis of randomised trials and an adjusted indirect comparison. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201 |
| Comments on the article by Routledge et al 'Three-year clinical outcome of percutaneous treatment of bifurcation lesions in multivessel coronary artery disease with the sirolimus-eluting stent: insights from the Arterial Revascularisation Therapies Study, part II (ARTS II)'. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20100201 |
| Rapamycin inhibits VEGF-induced microvascular hyperpermeability in vivo. | Microcirculation (New York, N.Y. : 1994) 20100201 |
| Long-term blood vessel removal with combined laser and topical rapamycin antiangiogenic therapy: implications for effective port wine stain treatment. | Lasers in surgery and medicine 20100201 |
| Impact of multiple and long sirolimus-eluting stent implantation on 3-year clinical outcomes in the j-Cypher Registry. | JACC. Cardiovascular interventions 20100201 |
| Impact of drug-eluting stent length on outcomes less is more...more or less. | JACC. Cardiovascular interventions 20100201 |
| Difference of neointimal formational pattern and incidence of thrombus formation among 3 kinds of stents: an angioscopic study. | JACC. Cardiovascular interventions 20100201 |
| [Effects of rapamycin-loaded poly(lactic-co-glycolic) acid nanoparticles on distribution of cell cycle, expression of p27 protein, and proliferation of human umbilical arterial vascular smooth muscle cell in vitro]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20100201 |
| Comparison of long-term results of drug-eluting stent and bare metal stent implantation in heart transplant recipients with coronary artery disease. | Kardiologia polska 20100201 |
| Influence of drug-eluting stent on inflammation during restenosis in a porcine coronary model. | Acta cardiologica 20100201 |
| The pathophysiology of tuberous sclerosis complex. | Epilepsia 20100201 |
| [Intravascular ultrasound evaluation on the efficacy of national made Firebird stents comparing with Cypher stents]. | Zhonghua xin xue guan bing za zhi 20100201 |
| [Treatment of locally advanced renal tumors]. | Actas urologicas espanolas 20100201 |
| Sirolimus-eluting stents versus paclitaxel-eluting stents in patients with chronic renal insufficiency. | Journal of interventional cardiology 20100201 |
| Resolvin E1 receptor activation signals phosphorylation and phagocytosis. | The Journal of biological chemistry 20100129 |
| Effect of different immunosuppressive schedules on recurrence-free survival after liver transplantation for hepatocellular carcinoma. | Transplantation 20100127 |
| Cyclosporine lowering with everolimus or mycophenolate to preserve renal function in heart recipients: a randomized study. | Transplantation 20100127 |
| Sirolimus-eluting stent implantation in small coronary arteries: a three dimensional intravascular ultrasound study from the SIRIUS trial. | International journal of cardiology 20100121 |
| Rapamycin protects against neuron death in in vitro and in vivo models of Parkinson's disease. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100120 |
| [mTOR and non-small cell lung cancer]. | Zhongguo fei ai za zhi = Chinese journal of lung cancer 20100120 |
| Second-generation everolimus-eluting and paclitaxel-eluting stents in real-life practice (COMPARE): a randomised trial. | Lancet (London, England) 20100116 |
| Everolimus or paclitaxel stents in real life: go COMPARE. | Lancet (London, England) 20100116 |
| Preclinical in vivo evaluation of rapamycin in human malignant peripheral nerve sheath explant xenograft. | International journal of cancer 20100115 |
| Omega-3 polyunsaturated fatty acids affect sirolimus exposure in kidney transplant recipients on calcineurin inhibitor-free regimen. | Transplantation 20100115 |
| Myxoma virus virotherapy for glioma in immunocompetent animal models: optimizing administration routes and synergy with rapamycin. | Cancer research 20100115 |
| The somatostatin analogue octreotide confers sensitivity to rapamycin treatment on pituitary tumor cells. | Cancer research 20100115 |
| Beyond rapalog therapy: preclinical pharmacology and antitumor activity of WYE-125132, an ATP-competitive and specific inhibitor of mTORC1 and mTORC2. | Cancer research 20100115 |
| Outcome of undersized drug-eluting stents for percutaneous coronary intervention of saphenous vein graft lesions. | The American journal of cardiology 20100115 |
| Hybrid inhibitors of phosphatidylinositol 3-kinase (PI3K) and the mammalian target of rapamycin (mTOR): design, synthesis, and superior antitumor activity of novel wortmannin-rapamycin conjugates. | Journal of medicinal chemistry 20100114 |
| Dysregulation of mTOR signaling in fragile X syndrome. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20100113 |
| Mechanisms of life span extension by rapamycin in the fruit fly Drosophila melanogaster. | Cell metabolism 20100106 |
| Depletion of mammalian target of rapamycin (mTOR) via siRNA mediated knockdown leads to stabilization of beta-catenin and elicits distinct features of cardiomyocyte hypertrophy. | FEBS letters 20100104 |
| Oral ulcers after a transplant. | The British journal of oral & maxillofacial surgery 20100101 |
| Everolimus-induced pneumonitis: report of the first case in a liver transplant recipient and review of treatment options. | Transplant international : official journal of the European Society for Organ Transplantation 20100101 |
| Phase 2 trial of erlotinib plus sirolimus in adults with recurrent glioblastoma. | Journal of neuro-oncology 20100101 |
| Rapamycin promotes arterial thrombosis in vivo: implications for everolimus and zotarolimus eluting stents. | European heart journal 20100101 |
| Celecoxib reduces the effects of acute and chronic UVB exposure in mice treated with therapeutically relevant immunosuppressive drugs. | International journal of cancer 20100101 |
| Late conversion of tacrolimus to sirolimus in a prednisone-free immunosuppression regimen in renal transplant patients. | Clinical transplantation 20100101 |
| mTOR inhibitor everolimus ameliorates progressive tubular dysfunction in chronic renal failure rats. | Biochemical pharmacology 20100101 |
| The PI3K/Akt and mTOR/P70S6K signaling pathways in human uveal melanoma cells: interaction with B-Raf/ERK. | Investigative ophthalmology & visual science 20100101 |
| Acute rejection after paediatric heart transplantation: far less common and less severe. | Transplant international : official journal of the European Society for Organ Transplantation 20100101 |
| Repeat renal allografts treated with sirolimus, cyclosporine, anti-thymocyte globulin induction and continuous steroids achieve similar immunosuppressive efficacy as primary transplants. | Clinical transplantation 20100101 |
| Long-term results after conversion from calcineurin inhibitors to sirolimus in renal transplant patients. | Clinical transplantation 20100101 |
| Acute rejection in low-toxicity regimens: clinical impact and risk factors in the Symphony study. | Clinical transplantation 20100101 |
| Phase I clinical and pharmacokinetic study of RAD001 (everolimus) administered daily to Japanese patients with advanced solid tumors. | Japanese journal of clinical oncology 20100101 |
| The sensing of essential amino acid deficiency in the anterior piriform cortex, that requires the uncharged tRNA/GCN2 pathway, is sensitive to wortmannin but not rapamycin. | Pharmacology, biochemistry, and behavior 20100101 |
| Cost-effectiveness of temsirolimus for first line treatment of advanced renal cell carcinoma. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20100101 |
| Rapamycin inhibits yeast nucleotide excision repair independently of tor kinases. | Toxicological sciences : an official journal of the Society of Toxicology 20100101 |
| Rapamycin impairs metabolism-secretion coupling in rat pancreatic islets by suppressing carbohydrate metabolism. | The Journal of endocrinology 20100101 |
| Mammalian target of rapamycin (mTOR) inhibition as a potential antiepileptogenic therapy: From tuberous sclerosis to common acquired epilepsies. | Epilepsia 20100101 |
| Glucocorticoids increase NPY gene expression in the arcuate nucleus by inhibiting mTOR signaling in rat hypothalamic organotypic cultures. | Peptides 20100101 |
| Rapamycin and CCI-779 inhibit the mammalian target of rapamycin signalling in hepatocellular carcinoma. | Liver international : official journal of the International Association for the Study of the Liver 20100101 |
| Noncanonical TGF-beta pathways, mTORC1 and Abl, in renal interstitial fibrogenesis. | American journal of physiology. Renal physiology 20100101 |
| Preliminary characterization of oral lesions associated with inhibitors of mammalian target of rapamycin in cancer patients. | Cancer 20100101 |
| Aortic dissection in a patient treated by sunitinib for metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20100101 |
| A novel mTOR activating protein protects dopamine neurons against oxidative stress by repressing autophagy related cell death. | Journal of neurochemistry 20100101 |
| Expression of metabolically targeted biomarkers in endometrial carcinoma. | Gynecologic oncology 20100101 |
| Systemic drugs for restenosis prevention: old idea, new drugs. | Cardiology 20100101 |
| Preventing restenosis after implantation of bare stents with oral rapamycin: a randomized angiographic and intravascular ultrasound study with a 5-year clinical follow-up. | Cardiology 20100101 |
| Failed rescue therapy with rapamycin after paraquat intoxication. | Clinical toxicology (Philadelphia, Pa.) 20100101 |
| An optical coherence tomography study of a biodegradable vs. durable polymer-coated limus-eluting stent: a LEADERS trial sub-study. | European heart journal 20100101 |
| Transcription factor GATA4 inhibits doxorubicin-induced autophagy and cardiomyocyte death. | The Journal of biological chemistry 20100101 |
| The application of electrostatic dry powder deposition technology to coat drug-eluting stents. | Pharmaceutical research 20100101 |
| A role for p38 stress-activated protein kinase in regulation of cell growth via TORC1. | Molecular and cellular biology 20100101 |
| Sirolimus-induced signaling modifications in Kaposi's sarcoma with resolution in a liver transplant recipient. | Clinical transplantation 20100101 |
| Proteinuria after conversion to sirolimus in kidney transplant recipients: impact of pre-existing proteinuria, graft function, and angiotensin-converting enzyme inhibitors/angiotensin-receptor antagonists. | Clinical transplantation 20100101 |
| Unravelling the endovascular microenvironment by optical coherence tomography. | European heart journal 20100101 |
| Daily oral everolimus activity in patients with metastatic pancreatic neuroendocrine tumors after failure of cytotoxic chemotherapy: a phase II trial. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100101 |
| Pharmacological modification of dendritic cells to promote their tolerogenicity in transplantation. | Methods in molecular biology (Clifton, N.J.) 20100101 |
| Recent progress in percutaneous coronary intervention: evolution of the drug-eluting stents, focus on the XIENCE V drug-eluting stent. | Coronary artery disease 20100101 |
| Treatment of mild-moderate calcified coronary lesions with sirolimus-eluting stent: real world data from a single center. | Coronary artery disease 20100101 |
| The impact of sirolimus on hepatocyte proliferation after living donor liver transplantation. | Clinical transplantation 20100101 |
| Anthropogenic factors and the risk of highly pathogenic avian influenza H5N1: prospects from a spatial-based model. | Veterinary research 20100101 |
| Influence of selective immunosuppressive drugs on the healing of exposed dogs' dental pulp capped with mineral trioxide aggregate. | Journal of endodontics 20100101 |
| Autophagy induction reduces mutant ataxin-3 levels and toxicity in a mouse model of spinocerebellar ataxia type 3. | Brain : a journal of neurology 20100101 |
| Pharmacological inhibition of phosphoinositide 3 and TOR kinases improves survival of Drosophila melanogaster. | Rejuvenation research 20100101 |
| Mammalian target of rapamycin (mTOR) induces proliferation and de-differentiation responses to three coordinate pathophysiologic stimuli (mechanical strain, hypoxia, and extracellular matrix remodeling) in rat bladder smooth muscle. | The American journal of pathology 20100101 |
| Drug-eluting stents for the treatment of acute myocardial infarction: the view to the HORIZONS. | Heart, lung & circulation 20100101 |
| Bevacizumab, sorafenib tosylate, sunitinib and temsirolimus for renal cell carcinoma: a systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20100101 |
| The role of the Akt/mTOR pathway in tobacco carcinogen-induced lung tumorigenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100101 |
| Vorinostat enhances the activity of temsirolimus in renal cell carcinoma through suppression of survivin levels. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100101 |
| Small-molecule inhibitors of phosphatidylinositol 3-kinase/Akt signaling inhibit Wnt/beta-catenin pathway cross-talk and suppress medulloblastoma growth. | Cancer research 20100101 |
| Early (fifth day) vs. late (sixth month) steroid withdrawal in renal transplant recipients treated with Neoral(®) plus Rapamune(®): four-yr results of a randomized monocenter study. | Clinical transplantation 20100101 |
| Reduction of cyclosporine following the introduction of everolimus in maintenance heart transplant recipients: a pilot study. | Transplant international : official journal of the European Society for Organ Transplantation 20100101 |
| Stage 2 combination testing of rapamycin with cytotoxic agents by the Pediatric Preclinical Testing Program. | Molecular cancer therapeutics 20100101 |
| The ATM inhibitor KU-55933 suppresses cell proliferation and induces apoptosis by blocking Akt in cancer cells with overactivated Akt. | Molecular cancer therapeutics 20100101 |
| Management of chronic allograft dysfunction by switch over to rapamycin. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20100101 |
| Temsirolimus. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20100101 |
| Quantitation of sirolimus using liquid chromatography-tandem mass spectrometry (LC-MS-MS). | Methods in molecular biology (Clifton, N.J.) 20100101 |
| Persistent effects of everolimus on strength of experimental wounds in intestine and fascia. | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20100101 |
| Progress in the management of advanced renal cell carcinoma (RCC). | Aktuelle Urologie 20100101 |
| Long-term laryngeal allograft survival using low-dose everolimus. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20100101 |
| Lingual angioedema associated with everolimus. | Acta oncologica (Stockholm, Sweden) 20100101 |
| Effect of rapamycin on lifespan in Drosophila. | Geriatrics & gerontology international 20100101 |
| Meta-analysis of five randomized clinical trials comparing sirolimus- versus paclitaxel-eluting stents in patients with diabetes mellitus. | The American journal of cardiology 20100101 |
| Sirolimus-eluting stent implantation for ostial stenosis of left main coronary artery after Bentall operation in aortitis syndrome. | Journal of cardiology 20100101 |
| Incidence and predictors of very late (>or=4 years) major cardiac adverse events in the DESIRE (Drug-Eluting Stents in the Real World)-Late registry. | JACC. Cardiovascular interventions 20100101 |
| First clinical experience of 'flower petal stenting': a novel technique for the treatment of coronary bifurcation lesions. | JACC. Cardiovascular interventions 20100101 |
| The artisan approach for stenting bifurcation lesions. | JACC. Cardiovascular interventions 20100101 |
| Anti-CD34 antibodies immobilized on the surface of sirolimus-eluting stents enhance stent endothelialization. | JACC. Cardiovascular interventions 20100101 |
| Drug-eluting stent endothelium: presence or dysfunction. | JACC. Cardiovascular interventions 20100101 |
| Increased restenosis rate after implantation of drug-eluting stents in patients with elevated serum activity of matrix metalloproteinase-2 and -9. | JACC. Cardiovascular interventions 20100101 |
| Regulation of gene expression in hepatic cells by the mammalian Target of Rapamycin (mTOR). | PloS one 20100101 |
| Lkb1 inactivation is sufficient to drive endometrial cancers that are aggressive yet highly responsive to mTOR inhibitor monotherapy. | Disease models & mechanisms 20100101 |
| [Stromal progenitor cells and blood leukocytes after implantation of drug-eluting stents]. | Kardiologiia 20100101 |
| Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors. | Journal of translational medicine 20100101 |
| [First-line therapy of metastatic renal cell carcinoma--update 2009]. | Onkologie 20100101 |
| [Current aspects of second-line and sequence therapy of metastatic renal cell carcinoma]. | Onkologie 20100101 |
| [Outlook: Future therapy of renal cell carcinoma]. | Onkologie 20100101 |
| Thrombotic microangiopathy following intestinal transplantation: a single center experience. | Transplantation proceedings 20100101 |
| Effects of immunosuppressive drugs on rat renal ischemia reperfusion injury. | Transplantation proceedings 20100101 |
| Everolimus versus azathioprine in a cyclosporine and ketoconazole-based immunosuppressive therapy in kidney transplant: 3-year follow-up of an open-label, prospective, cohort, comparative clinical trial. | Transplantation proceedings 20100101 |
| Results of the conversion to everolimus in renal transplant recipients with posttransplantation malignancies. | Transplantation proceedings 20100101 |
| Effectiveness and cost of replacing a calcineurin inhibitor with sirolimus to slow the course of chronic kidney disease in renal allografts. | Transplantation proceedings 20100101 |
| Conversion to sirolimus allows preservation of renal function in kidney and kidney-pancreas allograft recipients. | Transplantation proceedings 20100101 |
| South American Heart Transplantation Registry of patients receiving everolimus in their immunosuppressive regimens. | Transplantation proceedings 20100101 |
| Everolimus in lung transplantation in Chile. | Transplantation proceedings 20100101 |
| Sirolimus in kidney transplant donors and clinical and histologic improvement in recipients: rat model. | Transplantation proceedings 20100101 |
| In vitro and in vivo characterization of novel biodegradable polymers for application as drug-eluting stent coatings. | Journal of biomaterials science. Polymer edition 20100101 |
| mTOR inhibitor-associated dermatologic and mucosal problems. | Clinical transplantation 20100101 |
| Toxic tacrolimus blood levels with rifampin administration in a renal transplant recipient. | Annals of transplantation 20100101 |
| Sirolimus-eluting stent fractures leading to restenosis in cardiac allograft vasculopathy. | Cardiovascular revascularization medicine : including molecular interventions 20100101 |
| Rapamycin induces autophagy and exacerbates metabolism associated complications in a mouse model of type 1 diabetes. | Indian journal of experimental biology 20100101 |
| New therapeutic strategies for renal cell carcinoma. | Urologic nursing 20100101 |
| Evaluation of the firebird sirololimus eluting stent in all comers with coronary artery stenosis. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100101 |
| [Toxic effect of immunosuppression agent Everolimus on insuloma cells and pancreatic islets of SD rat]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100101 |
| Inhibition of mTOR by rapamycin abolishes cognitive deficits and reduces amyloid-beta levels in a mouse model of Alzheimer's disease. | PloS one 20100101 |
| A therapeutic exploratory study to determine the efficacy and safety of calcineurin-inhibitor-free de-novo immunosuppression after liver transplantation: CILT. | BMC surgery 20100101 |
| VEGF secretion by neuroendocrine tumor cells is inhibited by octreotide and by inhibitors of the PI3K/AKT/mTOR pathway. | Neuroendocrinology 20100101 |
| Sirolimus-based immunosuppression in kidney transplantation for type 2 diabetic nephropathy. | Urologia internationalis 20100101 |
| Pulmonary toxicity associated with sirolimus following kidney transplantation: computed tomography findings. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101 |
| Rapamycin inhibits re-endothelialization after percutaneous coronary intervention by impeding the proliferation and migration of endothelial cells and inducing apoptosis of endothelial progenitor cells. | Texas Heart Institute journal 20100101 |
| [Renal cell carcinoma management and therapies in 2010]. | Bulletin du cancer 20100101 |
| [mTOR inhibitors: temsirolimus and everolimus in the treatment of renal cell carcinoma]. | Bulletin du cancer 20100101 |
| [Targeted therapies: sequential and combined treatments]. | Bulletin du cancer 20100101 |
| [Management of side effects associated with antiangiogenic treatment in renal cell carcinoma]. | Bulletin du cancer 20100101 |
| [Advanced renal carcinomas with special situations. How to treat them?]. | Bulletin du cancer 20100101 |
| [Signalling pathways in renal-cell carcinoma: from the molecular biology to the future therapy]. | Bulletin du cancer 20100101 |
| Epidermal growth factor induces HCCR expression via PI3K/Akt/mTOR signaling in PANC-1 pancreatic cancer cells. | BMC cancer 20100101 |
| Anti-CD154 mAb and rapamycin induce T regulatory cell mediated tolerance in rat-to-mouse islet transplantation. | PloS one 20100101 |
| A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma. | BMC cancer 20100101 |
| Severe aphthous stomatitis associated with oral calcineurin and mTOR inhibitors. | International journal of dermatology 20100101 |
| Significant sirolimus and dronedarone interaction in a kidney transplant recipient. | The Annals of pharmacotherapy 20100101 |
| Different immunosuppressive combinations on T-cell regulation in renal transplant recipients. | American journal of nephrology 20100101 |
| Rapamycin inhibits IGF-1 stimulated cell motility through PP2A pathway. | PloS one 20100101 |
| Accelerated wound healing by mTOR activation in genetically defined mouse models. | PloS one 20100101 |
| [Change in regulations for dispensing immunosuppressants to patients who have undergone a kidney transplant]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101 |
| Xenotransplantation of hepatocytes in rats with acute liver failure using sirolimus for immunosuppression. | The Journal of international medical research 20100101 |
| mTOR regulates the invasive properties of synovial fibroblasts in rheumatoid arthritis. | Molecular medicine (Cambridge, Mass.) 20100101 |
| Rationale and design of a randomized clinical comparison of everolimus-eluting (Xience v/Promus) and sirolimus-eluting (cypher select+) coronary stents in unselected patients with coronary heart disease. | Cardiology 20100101 |
| mTOR signaling in cancer cell motility and tumor metastasis. | Critical reviews in eukaryotic gene expression 20100101 |
| Rapamycin pharmacokinetic and pharmacodynamic relationships in osteosarcoma: a comparative oncology study in dogs. | PloS one 20100101 |
| Drug-eluting stent thrombosis 1,659 days after stent deployment: case report and literature review. | Texas Heart Institute journal 20100101 |
| New inhibitors of the PI3K-Akt-mTOR pathway: insights into mTOR signaling from a new generation of Tor Kinase Domain Inhibitors (TORKinibs). | Current topics in microbiology and immunology 20100101 |
| Q-TWiST analysis of patients receiving temsirolimus or interferon alpha for treatment of advanced renal cell carcinoma. | PharmacoEconomics 20100101 |
| Rapamycin in combination with donor-specific CD4+CD25+Treg cells amplified in vitro might be realize the immune tolerance in clinical organ transplantation. | Cellular immunology 20100101 |
| Choice of immunosuppression influences cytomegalovirus DNAemia in cynomolgus monkey (Macaca fascicularis) islet allograft recipients. | Cell transplantation 20100101 |
| Comparison of the effect of preinterventional arterial remodeling on intimal hyperplasia after implantation of a sirolimus- or paclitaxel-eluting stent. | Cardiology 20100101 |
| Efficacy of sirolimus-eluting stents compared with paclitaxel-eluting stents in an unselected population with coronary artery disease: 24-month outcomes of patients in a prospective non-randomized registry in Southern Turkey. | International journal of medical sciences 20100101 |
| [Percutaneous copronary intervention using sirolimus-eluting stents may improve long-term prognosis of elderly women]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20100101 |
| Development of encapsulating peritoneal sclerosis in a renal transplant recipient on sirolimus immunotherapy. | Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20100101 |
| Inhibition of the mammalian target of rapamycin (mTOR) in advanced pancreatic cancer: results of two phase II studies. | BMC cancer 20100101 |
| Peripheral blood T regulatory cell counts may not predict transplant rejection. | BMC immunology 20100101 |
| Combination of rapamycin and IL-2 do not affect antigen presentation ability of rat B cell and could promote Tregs proliferation and inhibitory activity. | Cellular immunology 20100101 |
| [Interstitial pneumonitis from everolimus]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20100101 |
| HIV-1 inhibits autophagy in bystander macrophage/monocytic cells through Src-Akt and STAT3. | PloS one 20100101 |
| Severe stomatitis complicating immune-suppressive switch after cardiac transplantation. | Acta chirurgica Belgica 20100101 |
| Similar early complication rate in simultaneous pancreas and kidney recipients on tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus immunosuppressive regimens. | Transplantation proceedings 20100101 |
| Calcineurin inhibitors in renal transplantation still needed but in reduced doses: a review. | Transplantation proceedings 20100101 |
| Antivascular endothelial growth factor in diabetic retinopathy. | Developments in ophthalmology 20100101 |
| Mammalian target of rapamycin (mTOR) regulates TLR3 induced cytokines in human oral keratinocytes. | Molecular immunology 20100101 |
| The effects of rapamycin on lens epithelial cell proliferation, migration, and matrix formation: an in vitro study. | Molecular vision 20100101 |
| Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphoma. | Journal of hematology & oncology 20100101 |
| Study protocol: a pilot study to determine the safety and efficacy of induction-therapy, de novo MPA and delayed mTOR-inhibition in liver transplant recipients with impaired renal function. PATRON-study. | BMC nephrology 20100101 |
| Asymptomatic migration of a sirolimus-eluting stent into the aorta. | Internal medicine (Tokyo, Japan) 20100101 |
| A randomized pilot study of systemic immunosuppression in the treatment of age-related macular degeneration with choroidal neovascularization. | Retina (Philadelphia, Pa.) 20100101 |
| Metabolic engineering of resveratrol and other longevity boosting compounds. | BioFactors (Oxford, England) 20100101 |
| Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging. | BioFactors (Oxford, England) 20100101 |
| The DTH effector response and IL-2 are unaffected by cyclosporine A in autoimmune B6D2F1 mice. | Cellular immunology 20100101 |
| Rationale and design of EXPLORE: a randomized, prospective, multicenter trial investigating the impact of recanalization of a chronic total occlusion on left ventricular function in patients after primary percutaneous coronary intervention for acute ST-elevation myocardial infarction. | Trials 20100101 |
| Antitumour activity of a potent MEK inhibitor RDEA119/BAY 869766 combined with rapamycin in human orthotopic primary pancreatic cancer xenografts. | BMC cancer 20100101 |
| Activated mammalian target of rapamycin is a potential therapeutic target in gastric cancer. | BMC cancer 20100101 |
| Thrombogenicity of sirolimus-eluting stents and bare metal stents: evaluation in the early phase after stent implantation. | In vivo (Athens, Greece) 20100101 |
| Rapamycin therapy for renal, brain, and skin lesions in a tuberous sclerosis patient. | Renal failure 20100101 |
| Pretreatment with intraluminal rapamycin nanoparticle perfusion inhibits neointimal hyperplasia in a rabbit vein graft model. | International journal of nanomedicine 20100101 |
| Small coronary vessel angioplasty: outcomes and technical considerations. | Vascular health and risk management 20100101 |
| Rapamycin sensitizes T-ALL cells to dexamethasone-induced apoptosis. | Journal of experimental & clinical cancer research : CR 20100101 |
| Improved outcome after 'bottom-up' immunosuppression in liver transplant recipients with preoperative renal impairment. | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20100101 |
| Targeted therapy in lymphoma. | Journal of hematology & oncology 20100101 |
| Rrd1 isomerizes RNA polymerase II in response to rapamycin. | BMC molecular biology 20100101 |
| Teaching an old drug new tricks: metformin as a targeted therapy for lung cancer. | Seminars in thoracic and cardiovascular surgery 20100101 |
| A comprehensive map of the mTOR signaling network. | Molecular systems biology 20100101 |
| Primary PCI for acute anterior wall MI with pulmonary edema and left anterior descending artery ostial stenosis. | Indian heart journal 20100101 |
| Preclinical evaluation of KIT/PDGFRA and mTOR inhibitors in gastrointestinal stromal tumors using small animal FDG PET. | Journal of experimental & clinical cancer research : CR 20100101 |
| Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition. | PloS one 20100101 |
| Clinical studies with sirolimus, zotarolimus, everolimus, and biolimus A9 drug-eluting stent systems. | Current pharmaceutical design 20100101 |
| Sirolimus and its analogs and its effects on vascular diseases. | Current pharmaceutical design 20100101 |
| The Drosophila FoxA ortholog Fork head regulates growth and gene expression downstream of Target of rapamycin. | PloS one 20100101 |
| Is it possible to optimize the use of targeted therapies in the treatment of renal cell carcinoma? | Tumori 20100101 |
| Perspectives in the development of novel treatment approaches. | Tumori 20100101 |
| Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy. | Cell death & disease 20100101 |
| [Financial justification of investments into special diet for patients with phenylketonuria]. | Medicinski pregled 20100101 |
| [Long-term follow-up use of 'cypher' sirolimus-eluting stents in patients with coronary heart disease after coronary artery bypass grafting with occlusive lesions of the coronary artery]. | Vestnik rentgenologii i radiologii 20100101 |
| Rapamycin increases the p53/MDM2 protein ratio and p53-dependent apoptosis by translational inhibition of mdm2 in cancer cells. | Cancer letters 20091228 |
| Impact of reduced nephron mass on cyclosporine- and/or sirolimus-induced nephrotoxicity. | Transplantation 20091227 |
| Bortezomib can suppress activation of rapamycin-resistant memory T cells without affecting regulatory T-cell viability in non-human primates. | Transplantation 20091227 |
| A chemical genetic screen for mTOR pathway inhibitors based on 4E-BP-dependent nuclear accumulation of eIF4E. | Chemistry & biology 20091224 |
| Coronary aneurysm and very late stent thrombosis formation associated with sirolimus-eluting stent implantation. | Chinese medical journal 20091220 |
| Cardiac-specific deletion of LKB1 leads to hypertrophy and dysfunction. | The Journal of biological chemistry 20091218 |
| Breakthrough of the year. The runners-up. | Science (New York, N.Y.) 20091218 |
| [Autosomal dominant polycystic kidney disease (ADPKD): rapamycin as a new treatment option]. | Praxis 20091216 |
| Pharmacologic induction of CD8+ T cell memory: better living through chemistry. | Science translational medicine 20091216 |
| Three-dimensional time-of-flight secondary ion mass spectrometry imaging of a pharmaceutical in a coronary stent coating as a function of elution time. | Analytical chemistry 20091215 |
| TOR-driven aging: speeding car without brakes. | Cell cycle (Georgetown, Tex.) 20091215 |
| Pseudo-DNA damage response in senescent cells. | Cell cycle (Georgetown, Tex.) 20091215 |
| Histopathology of clinical coronary restenosis in drug-eluting versus bare metal stents. | The American journal of cardiology 20091215 |
| Prolonged survival of composite facial allografts in non-human primates associated with posttransplant lymphoproliferative disorder. | Transplantation 20091215 |
| EGFR signaling through an Akt-SREBP-1-dependent, rapamycin-resistant pathway sensitizes glioblastomas to antilipogenic therapy. | Science signaling 20091215 |
| Beneficial effects of Mammalian target of rapamycin inhibition on left ventricular remodeling after myocardial infarction. | Journal of the American College of Cardiology 20091215 |
| Assimilating the current clinical data of fully bioabsorbable stents. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215 |
| Novel fully bioabsorbable salicylate-based sirolimus-eluting stent. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215 |
| OrbusNeich fully absorbable coronary stent platform incorporating dual partitioned coatings. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215 |
| NEVO™: a new generation of sirolimus-eluting coronary stent. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215 |
| Everolimus-eluting bioabsorbable stent--Abbot Vascular programme. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091215 |
| Allogeneic hematopoietic stem-cell transplantation for sickle cell disease. | The New England journal of medicine 20091210 |
| Hematopoietic stem-cell transplantation for adults with sickle cell disease. | The New England journal of medicine 20091210 |
| Structural identification and characterization of potential degradants of zotarolimus on zotarolimus-coated drug-eluting stents. | Journal of pharmaceutical and biomedical analysis 20091205 |
| Blockade of Hsp20 phosphorylation exacerbates cardiac ischemia/reperfusion injury by suppressed autophagy and increased cell death. | Circulation research 20091204 |
| Limited sampling strategies for sirolimus after pediatric renal transplantation. | Pediatric transplantation 20091201 |
| Optical coherence tomography evaluation of zotarolimus-eluting stents at 9-month follow-up: comparison with sirolimus-eluting stents. | Heart (British Cardiac Society) 20091201 |
| Phosphorylation of translation factors in response to anoxia in turtles, Trachemys scripta elegans: role of the AMP-activated protein kinase and target of rapamycin signalling pathways. | Molecular and cellular biochemistry 20091201 |
| Rapid regression of lymphadenopathy upon rapamycin treatment in a child with autoimmune lymphoproliferative syndrome. | Pediatric blood & cancer 20091201 |
| Treatment with sirolimus ameliorates tacrolimus-induced autoimmune cytopenias after solid organ transplant. | Pediatric blood & cancer 20091201 |
| Quantitative coronary angiography in the current era: principles and applications. | Journal of interventional cardiology 20091201 |
| Rapamycin impairs trabecular bone acquisition from high-dose but not low-dose intermittent parathyroid hormone treatment. | Journal of cellular physiology 20091201 |
| Rapamycin induces the TGFbeta1/Smad signaling cascade in renal mesangial cells upstream of mTOR. | Cellular signalling 20091201 |
| Transfer from ciclosporin to mycophenolate-sirolimus immunosuppression for chronic renal disease after heart transplantation: safety and efficacy of two regimens. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201 |
| Rapamycin has dual opposing effects on proteinuric experimental nephropathies: is it a matter of podocyte damage? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201 |
| Rapamycin protects against rotenone-induced apoptosis through autophagy induction. | Neuroscience 20091201 |
| Quality of life in patients with metastatic renal cell carcinoma: the importance of patient-reported outcomes. | Cancer treatment reviews 20091201 |
| The carina angle-new geometrical parameter associated with periprocedural side branch compromise and the long-term results in coronary bifurcation lesions with main vessel stenting only. | Journal of interventional cardiology 20091201 |
| Emerging drugs for coronary restenosis: the role of systemic oral agents the in stent era. | Expert opinion on emerging drugs 20091201 |
| A phase I/II study of the safety and efficacy of the addition of sirolimus to tacrolimus/methotrexate graft versus host disease prophylaxis after allogeneic haematopoietic cell transplantation in paediatric acute lymphoblastic leukaemia (ALL). | British journal of haematology 20091201 |
| CDKs as therapeutic targets for the human genetic disease tuberous sclerosis? | European journal of clinical investigation 20091201 |
| Five-year clinical outcomes after coronary stenting of chronic total occlusion using sirolimus-eluting stents: insights from the rapamycin-eluting stent evaluated at Rotterdam Cardiology Hospital-(Research) Registry. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201 |
| Exploring mammalian target of rapamycin (mTOR) inhibition for treatment of mantle cell lymphoma and other hematologic malignancies. | Leukemia & lymphoma 20091201 |
| Rapamycin enhances lifespan: at last, an advantage for transplant recipients? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201 |
| Pulse mTOR inhibitor treatment effectively controls cyst growth but leads to severe parenchymal and glomerular hypertrophy in rat polycystic kidney disease. | American journal of physiology. Renal physiology 20091201 |
| The multifunctional role of mTOR in innate immunity: implications for transplant immunity. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20091201 |
| Long-term follow-up of neointimal coverage of sirolimus-eluting stents--evaluation with optical coherence tomography. | Circulation journal : official journal of the Japanese Circulation Society 20091201 |
| Lack of clinical benefit of improved angiographic results with sirolimus-eluting stents compared with paclitaxel and zotarolimus-eluting stents in patients with acute myocardial infarction undergoing percutaneous coronary intervention. | Circulation journal : official journal of the Japanese Circulation Society 20091201 |
| Effect of itraconazole on the pharmacokinetics of everolimus administered by different routes in rats. | Biopharmaceutics & drug disposition 20091201 |
| mTOR regulates skeletal muscle regeneration in vivo through kinase-dependent and kinase-independent mechanisms. | American journal of physiology. Cell physiology 20091201 |
| Effects of chronic overload on muscle hypertrophy and mTOR signaling in young adult and aged rats. | The journals of gerontology. Series A, Biological sciences and medical sciences 20091201 |
| Significance and management of proteinuria in kidney transplant recipients. | Journal of the American Society of Nephrology : JASN 20091201 |
| Five-year clinical follow-up after implantation of the Endeavor zotarolimus-eluting stent: ENDEAVOR I, first-in-human study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201 |
| TOR complex 2: a signaling pathway of its own. | Trends in biochemical sciences 20091201 |
| Characterization of p70 S6 kinase 1 in early development of mouse embryos. | Developmental dynamics : an official publication of the American Association of Anatomists 20091201 |
| Mammalian target of rapamycin is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats. | Hypertension (Dallas, Tex. : 1979) 20091201 |
| The rationale for mTOR inhibition in epithelial ovarian cancer. | Expert opinion on investigational drugs 20091201 |
| Low toxicity regimens in renal transplantation: a country subset analysis of the Symphony study. | Transplant international : official journal of the European Society for Organ Transplantation 20091201 |
| Evaluation of in vivo antineoplastic effects of rapamycin in patients with chemotherapy-refractory AML. | European journal of internal medicine 20091201 |
| Pharmacological retention of oral mucosa progenitor/stem cells. | Journal of dental research 20091201 |
| Oral rapamycin attenuates atherosclerosis without affecting the arterial responsiveness of resistance vessels in apolipoprotein E-deficient mice. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20091201 |
| Targeting mTOR globally in cancer: thinking beyond rapamycin. | Cell cycle (Georgetown, Tex.) 20091201 |
| Emerging treatment combinations: integrating therapy into clinical practice. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20091201 |
| Targeting translation in acute myeloid leukemia: a new paradigm for therapy? | Cell cycle (Georgetown, Tex.) 20091201 |
| Impact of sirolimus on the recurrence of hepatocellular carcinoma after liver transplantation. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091201 |
| Improvement of renal function after the switch from a calcineurin inhibitor to everolimus in liver transplant recipients with chronic renal dysfunction. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091201 |
| Delayed neointimalization on drug-eluting stents--speculation from optical coherence tomography. | Circulation journal : official journal of the Japanese Circulation Society 20091201 |
| Metastatic renal cell carcinoma: current standards of care. | Clinical journal of oncology nursing 20091201 |
| Management of mTOR inhibitor side effects. | Clinical journal of oncology nursing 20091201 |
| The role of mTOR in bladder cancer. | Cancer biology & therapy 20091201 |
| Comparison of sirolimus and paclitaxel-eluting stents for complex coronary lesions: an intravascular ultrasound study. | The Korean journal of internal medicine 20091201 |
| Rapamycin versus methotrexate in early diffuse systemic sclerosis: results from a randomized, single-blind pilot study. | Arthritis and rheumatism 20091201 |
| Intravesical delivery of rapamycin suppresses tumorigenesis in a mouse model of progressive bladder cancer. | Cancer prevention research (Philadelphia, Pa.) 20091201 |
| The molecular, the bad, and the ugly: preventing bladder cancer via mTOR inhibition. | Cancer prevention research (Philadelphia, Pa.) 20091201 |
| Are we totally clear? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201 |
| The long-term results of the 'Endeavor' stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091201 |
| Rationale and design of the Patient Related OuTcomes with Endeavor versus Cypher stenting Trial (PROTECT): randomized controlled trial comparing the incidence of stent thrombosis and clinical events after sirolimus or zotarolimus drug-eluting stent implantation. | American heart journal 20091201 |
| Clinical and angiographic comparison of everolimus-eluting and paclitaxel-eluting stents in small coronary arteries: a post hoc analysis of the SPIRIT III randomized trial. | American heart journal 20091201 |
| Clinical development of temsirolimus, a novel mTOR inhibitor, for treatment of advanced malignancies. | Seminars in oncology 20091201 |
| Intravenous temsirolimus in cancer patients: clinical pharmacology and dosing considerations. | Seminars in oncology 20091201 |
| Clinical trial experience with temsirolimus in patients with advanced renal cell carcinoma. | Seminars in oncology 20091201 |
| Mammalian target of rapamycin: discovery of rapamycin reveals a signaling pathway important for normal and cancer cell growth. | Seminars in oncology 20091201 |
| Temsirolimus in mantle cell lymphoma and other non-Hodgkin lymphoma subtypes. | Seminars in oncology 20091201 |
| Evaluating temsirolimus activity in multiple tumors: a review of clinical trials. | Seminars in oncology 20091201 |
| Preprocedural inflammation does not affect neointimal hyperplasia following everolimus-eluting stent implantation. | The Journal of invasive cardiology 20091201 |
| Late-acquired stent malapposition after sirolimus-eluting stent implantation following acute coronary syndrome: angiographic, IVUS, OCT and coronary angioscopic observation. | The Journal of invasive cardiology 20091201 |
| Chinese 'Firebird' brand sirolimus-eluting stent fracture. | The Journal of invasive cardiology 20091201 |
| Very late subacute thrombosis of a sirolimus-eluting stent after 57 months. | The Journal of invasive cardiology 20091201 |
| Translational modulation of proteins expressed from bicistronic vectors. | Molecular imaging 20091201 |
| Effects of delayed rapamycin treatment on renal fibrosis and inflammation in experimental ischemia reperfusion injury. | Transplantation proceedings 20091201 |
| Potential differences in kidney allograft outcomes between ethnicities when converting to sirolimus base immunosuppression. | Transplantation proceedings 20091201 |
| Renal function outcomes in kidney transplant recipients after conversion to everolimus-based immunosuppression regimen with CNI reduction or elimination. | Transplantation proceedings 20091201 |
| Improved 24-hour blood pressure control with sirolimus versus calcineurin inhibitor based immunosuppression in renal transplant recipients. | Transplantation proceedings 20091201 |
| Immunosuppression using the mammalian target of rapamycin (mTOR) inhibitor everolimus: pilot study shows significant cognitive and affective improvement. | Transplantation proceedings 20091201 |
| Three year follow-up of the sirolimus-eluting stent and the paclitaxel-eluting stent in daily practice. | Clinical cardiology 20091201 |
| Prognostic values of C-reactive protein levels on clinical outcome after implantation of sirolimus-eluting stents in patients on hemodialysis. | Circulation. Cardiovascular interventions 20091201 |
| In-hospital and mid-term clinical outcomes after percutaneous coronary intervention with the use of sirolimus- or paclitaxel-eluting stents. | Kardiologia polska 20091201 |
| Inhibition of mammalian target of rapamycin as a therapeutic strategy in the management of bladder cancer. | Cancer biology & therapy 20091201 |
| [Benefits of proliferation signal inhibitors beyond immunosuppression. Vascular protection and experience in heart transplantation]. | Nephrologie & therapeutique 20091201 |
| [Proliferation signal inhibitors: what therapeutic protocols are followed in 2009?]. | Nephrologie & therapeutique 20091201 |
| [Replacing calcineurin inhibitors with proliferation signal inhibitors after kidney transplantation: indications, results, and disadvantages]. | Nephrologie & therapeutique 20091201 |
| The first-generation drug-eluting stents and coronary endothelial dysfunction. | JACC. Cardiovascular interventions 20091201 |
| 3-year clinical follow-up of the XIENCE V everolimus-eluting coronary stent system in the treatment of patients with de novo coronary artery lesions: the SPIRIT II trial (Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions). | JACC. Cardiovascular interventions 20091201 |
| Long-term clinical and economic analysis of the Endeavor zotarolimus-eluting stent versus the cypher sirolimus-eluting stent: 3-year results from the ENDEAVOR III trial (Randomized Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Cypher Sirolimus-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions). | JACC. Cardiovascular interventions 20091201 |
| Late safety, efficacy, and cost-effectiveness of a zotarolimus-eluting stent compared with a paclitaxel-eluting stent in patients with de novo coronary lesions: 2-year follow-up from the ENDEAVOR IV trial (Randomized, Controlled Trial of the Medtronic Endeavor Drug [ABT-578] Eluting Coronary Stent System Versus the Taxus Paclitaxel-Eluting Coronary Stent System in De Novo Native Coronary Artery Lesions). | JACC. Cardiovascular interventions 20091201 |
| Clinical outcomes after unrestricted implantation of everolimus-eluting stents. | JACC. Cardiovascular interventions 20091201 |
| Safety and effectiveness of the Endeavor zotarolimus-eluting stent in real-world clinical practice: 12-month data from the E-Five registry. | JACC. Cardiovascular interventions 20091201 |
| Evaluation in 3 months duration of neointimal coverage after zotarolimus-eluting stent implantation by optical coherence tomography: the ENDEAVOR OCT trial. | JACC. Cardiovascular interventions 20091201 |
| Progression of late stent malapposition beyond 2 years after sirolimus-eluting stent implantation. | JACC. Cardiovascular interventions 20091201 |
| Quantifying pharmacologic suppression of cellular senescence: prevention of cellular hypertrophy versus preservation of proliferative potential. | Aging 20091201 |
| [Are stents eluting sirolimus and paclitaxel equally efficacious?]. | Kardiologia polska 20091201 |
| Rationale and design for the PAINT randomized trial. | Arquivos brasileiros de cardiologia 20091201 |
| Temsirolimus for the treatment of mantle cell lymphoma. | Expert review of hematology 20091201 |
| Drug repositioning using in silico compound profiling. | Future medicinal chemistry 20091201 |
| Cyclin D1 induction by benzo[a]pyrene-7,8-diol-9,10-epoxide via the phosphatidylinositol 3-kinase/Akt/MAPK- and p70s6k-dependent pathway promotes cell transformation and tumorigenesis. | The Journal of biological chemistry 20091127 |
| Fibrogenesis in kidney transplantation: potential targets for prevention and therapy. | Transplantation 20091127 |
| Everolimus with very low-exposure cyclosporine a in de novo kidney transplantation: a multicenter, randomized, controlled trial. | Transplantation 20091127 |
| Discovery of potent and selective inhibitors of the mammalian target of rapamycin (mTOR) kinase. | Journal of medicinal chemistry 20091126 |
| A rapamycin-sensitive signaling pathway is essential for the full expression of persistent pain states. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20091125 |
| Regulation of SREBP1c expression by mTOR signaling in hepatocytes. | The Kobe journal of medical sciences 20091124 |
| If mammalian target of metformin indirectly is mammalian target of rapamycin, then the insulin-like growth factor-1 receptor axis will audit the efficacy of metformin in cancer clinical trials. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091120 |
| The role of mTORC1 pathway in intestinal tumorigenesis. | Cell cycle (Georgetown, Tex.) 20091115 |
| Clinical outcomes after sirolimus-eluting, paclitaxel-eluting, and bare metal stents (from the first phase of the prospective multicenter German DES.DE Registry). | The American journal of cardiology 20091115 |
| Comparison of the efficacy and safety of zotarolimus-, sirolimus-, and paclitaxel-eluting stents in patients with ST-elevation myocardial infarction. | The American journal of cardiology 20091115 |
| Rapamycin for refractory acute graft-versus-host disease. | Transplantation 20091115 |
| [The effect of the different immunosuppression therapy on CD4(+)Foxp3(+) Treg cells in kidney recipients]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20091115 |
| Three-year outcomes after sirolimus-eluting stent implantation for unprotected left main coronary artery disease: insights from the j-Cypher registry. | Circulation 20091110 |
| The 5-year clinical outcomes after a randomized comparison of sirolimus-eluting versus bare-metal stent implantation in patients with ST-segment elevation myocardial infarction. | Journal of the American College of Cardiology 20091110 |
| Differential healing after sirolimus, paclitaxel, and bare metal stent placement in combination with peroxisome proliferator-activator receptor gamma agonists: requirement for mTOR/Akt2 in PPARgamma activation. | Circulation research 20091106 |
| Conversion to sirolimus of patients with chronic allograft nephropathy--a retrospective analysis of outcome and influencing factors. | Langenbeck's archives of surgery 20091101 |
| Therapeutic drug monitoring of everolimus using the dried blood spot method in combination with liquid chromatography-mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20091101 |
| Variations in the effects on synthesis of amyloid beta protein in modulated autophagic conditions. | Neurological research 20091101 |
| Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis. | American journal of respiratory cell and molecular biology 20091101 |
| Phase II trial of temsirolimus in patients with relapsed or refractory multiple myeloma. | Leukemia research 20091101 |
| Safety and tolerability of sirolimus treatment in patients with autosomal dominant polycystic kidney disease. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091101 |
| Gender-based evaluation of the XIENCE V everolimus-eluting coronary stent system: clinical and angiographic results from the SPIRIT III randomized trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091101 |
| Response to imatinib plus sirolimus in advanced chordoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20091101 |
| Involvement of mTOR kinase in cytokine-dependent microglial activation and cell proliferation. | Biochemical pharmacology 20091101 |
| Tumour flare during interruption of temsirolimus treatment for metastatic renal cell cancer. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20091101 |
| Randomized evaluation of two drug-eluting stents with identical metallic platform and biodegradable polymer but different agents (paclitaxel or sirolimus) compared against bare stents: 1-year results of the PAINT trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20091101 |
| Critical roles for the TSC-mTOR pathway in β-cell function. | American journal of physiology. Endocrinology and metabolism 20091101 |
| Rapamycin selectively inhibits expression of an inducible keratin (K6a) in human keratinocytes and improves symptoms in pachyonychia congenita patients. | Journal of dermatological science 20091101 |
| Predictors and prognosis of stent fracture after sirolimus-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20091101 |
| Cryptosporidiosis in paediatric renal transplantation. | Pediatric nephrology (Berlin, Germany) 20091101 |
| Spreading of mesothelioma cells is rapamycin-sensitive and requires continuing translation. | Journal of cellular biochemistry 20091101 |
| Insulin resistance without elevated mammalian target of rapamycin complex 1 activity in muscles of mice fed a high-fat diet. | Journal of applied physiology (Bethesda, Md. : 1985) 20091101 |
| Characterization of pneumonitis in patients with advanced non-small cell lung cancer treated with everolimus (RAD001). | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20091101 |
| Distinct subsets of Sit4 holophosphatases are required for inhibition of Saccharomyces cerevisiae growth by rapamycin and zymocin. | Eukaryotic cell 20091101 |
| Clinical outcomes of sirolimus-eluting stenting after rotational atherectomy. | Circulation journal : official journal of the Japanese Circulation Society 20091101 |
| Development and validation of a semi-automated assay for the highly sensitive quantification of Biolimus A9 in human whole blood using high-performance liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20091101 |
| Morbus Crohn--a disease of failing macroautophagy in the immune system? | International immunology 20091101 |
| Everolimus but not mycophenolate mofetil therapy is associated with soluble HLA-G expression in heart transplant patients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20091101 |
| Sirolimus-eluting stent placement for refractory renal artery in-stent restenosis: sustained patency and clinical benefit at 24 months. | Vascular medicine (London, England) 20091101 |
| The stent-eluting drugs sirolimus and paclitaxel suppress healing of the endothelium by induction of autophagy. | The American journal of pathology 20091101 |
| Balancing needs and means: the dilemma of the beta-cell in the modern world. | Diabetes, obesity & metabolism 20091101 |
| Downregulation of 18F-FDG uptake in PET as an early pharmacodynamic effect in treatment of non-small cell lung cancer with the mTOR inhibitor everolimus. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20091101 |
| Interstitial fibrosis quantification in renal transplant recipients randomized to continue cyclosporine or convert to sirolimus. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20091101 |
| A phase I study of the mammalian target of rapamycin inhibitor sirolimus and MEC chemotherapy in relapsed and refractory acute myelogenous leukemia. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091101 |
| Transplantation: time to rethink immunosuppression by mTOR inhibitors? | Nature reviews. Nephrology 20091101 |
| HOTLINE II, ISAR-TEST-4 trial, biodegradable stent coatings show promise. | European heart journal 20091101 |
| Covered stent for the treatment of coronary aneurysm after sirolimus-eluting stent implantation in a patient with Takayasu's arteritis. | The Journal of invasive cardiology 20091101 |
| Sirolimus therapy for patients with adult polycystic kidney disease: a pilot study. | Transplantation proceedings 20091101 |
| Rapamycin as a therapy of choice after renal transplantation in a patient with tuberous sclerosis complex. | Transplantation proceedings 20091101 |
| Usefulness of sirolimus as rescue therapy in heart transplant recipients with renal failure: analysis of the Spanish Multicenter Observational Study (RAPACOR). | Transplantation proceedings 20091101 |
| [Conversion to rapamycin in liver transpant recipients with renal insufficiency]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20091101 |
| Sirolimus: a novel immunosuppressive drug in heart transplantation. | Recent patents on cardiovascular drug discovery 20091101 |
| Long-term risk of adverse outcomes and new malignancies in patients treated with oral sirolimus for prevention of restenosis. | JACC. Cardiovascular interventions 20091101 |
| No association of chromosome 9p21.3 variation with clinical and angiographic outcomes after placement of drug-eluting stents. | JACC. Cardiovascular interventions 20091101 |
| Comparison of long-term outcomes following sirolimus-eluting stent vs paclitaxel-eluting stent implantation in patients with long calcified coronary lesions. | Clinical cardiology 20091101 |
| Cost analysis of sirolimus-eluting stents in the Japanese health insurance system. | International heart journal 20091101 |
| Long-term effects of novel biodegradable, polymer-coated, sirolimus-eluting stents on neointimal formation in a porcine coronary model. | International heart journal 20091101 |
| [Indications of mTOR inhibitors in liver transplantation]. | Gastroenterologie clinique et biologique 20091101 |
| Everolimus de novo in liver transplantation. | Gastroenterologie clinique et biologique 20091101 |
| [Minimize kidney failure in transplantation patients with proliferation signal inhibitors]. | Gastroenterologie clinique et biologique 20091101 |
| [Liver transplantation for hepatocellular carcinoma and potential application of PSI]. | Gastroenterologie clinique et biologique 20091101 |
| [Antitumoral effect of proliferation signal inhibitors]. | Gastroenterologie clinique et biologique 20091101 |
| [Side effects of proliferation signal inhibitors and their management]. | Gastroenterologie clinique et biologique 20091101 |
| Impact of sirolimus-eluting stent implantation compared to bare-metal stent implantation for acute myocardial infarction on coronary plaque composition at nine months follow-up: a Virtual Histology intravascular ultrasound analysis. Results from the Leiden MISSION! intervention study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091101 |
| How should I treat a complex Post-CABG patient? | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20091101 |
| Prospective observational study of sirolimus as primary immunosuppression after renal transplantation. | Transplantation 20091027 |
| Everolimus: in advanced renal cell carcinoma. | Drugs 20091022 |
| Synergistic anti-cancer effects of immunotoxin and cyclosporin in vitro and in vivo. | British journal of cancer 20091020 |
| Preparation and in vitro release profiles of drug-eluting controlled biodegradable polymer coating stents. | Colloids and surfaces. B, Biointerfaces 20091015 |
| A novel PTEN-dependent link to ubiquitination controls FLIPS stability and TRAIL sensitivity in glioblastoma multiforme. | Cancer research 20091015 |
| Gastric cancer: trastuzumab trial results spur search for other targets. | Journal of the National Cancer Institute 20091007 |
| mTOR signaling in epileptogenesis: too much of a good thing? | The Journal of neuroscience : the official journal of the Society for Neuroscience 20091007 |
| Recurrent acute myocardial infarction after 32 months: very late stent thrombosis after sirolimus-eluting stent implantation. | Chinese medical journal 20091005 |
| Specification of neuronal polarity regulated by local translation of CRMP2 and Tau via the mTOR-p70S6K pathway. | The Journal of biological chemistry 20091002 |
| Rapamycin rescues TDP-43 mislocalization and the associated low molecular mass neurofilament instability. | The Journal of biological chemistry 20091002 |
| Cell signaling. Aging is RSKy business. | Science (New York, N.Y.) 20091002 |
| Antitumoral activity of rapamycin mediated through inhibition of HIF-1alpha and VEGF in hepatocellular carcinoma. | Digestive diseases and sciences 20091001 |
| Pathological finding of sirolimus-eluting stent (SES) restenosis lesion with black hole appearance on intravascular ultrasound. | Circulation journal : official journal of the Japanese Circulation Society 20091001 |
| Activation of the mammalian target of rapamycin signalling pathway in prostate cancer and its association with patient clinicopathological characteristics. | BJU international 20091001 |
| Inhibition of mammalian target of rapamycin (mTOR) signalling in C2C12 myoblasts prevents myogenic differentiation without affecting the hyperphosphorylation of 4E-BP1. | Cellular signalling 20091001 |
| Distribution of angiographic measures of restenosis after drug-eluting stent implantation. | Heart (British Cardiac Society) 20091001 |
| Growth failure associated with sirolimus: case report. | Pediatric nephrology (Berlin, Germany) 20091001 |
| Rapamycin-treated mature dendritic cells have a unique cytokine secretion profile and impaired allostimulatory capacity. | Transplant international : official journal of the European Society for Organ Transplantation 20091001 |
| Inhibition of mammalian target of rapamycin signaling potentiates the effects of all-trans retinoic acid to induce growth arrest and differentiation of human acute myelogenous leukemia cells. | International journal of cancer 20091001 |
| Role of the novel mTOR inhibitor RAD001 (everolimus) in anaplastic thyroid cancer. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20091001 |
| Efficacy of everolimus (RAD001) in patients with advanced NSCLC previously treated with chemotherapy alone or with chemotherapy and EGFR inhibitors. | Annals of oncology : official journal of the European Society for Medical Oncology 20091001 |
| Targeting the mammalian target of Rapamycin to inhibit VEGF and cytokines for the treatment of primary effusion lymphoma. | Leukemia 20091001 |
| Multi-site analytical evaluation of a chemiluminescent magnetic microparticle immunoassay (CMIA) for sirolimus on the Abbott ARCHITECT analyzer. | Clinical biochemistry 20091001 |
| Effective treatment of advanced colorectal cancer by rapamycin and 5-FU/oxaliplatin monitored by TIMP-1. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20091001 |
| Mammalian target of rapamycin is activated in association with myometrial proliferation during pregnancy. | Endocrinology 20091001 |
| Mechanical properties, drug eluting characteristics and in vivo performance of a genipin-crosslinked chitosan polymeric stent. | Biomaterials 20091001 |
| Signal transducer and activator of transcription 3 is required for abnormal proliferation and survival of TSC2-deficient cells: relevance to pulmonary lymphangioleiomyomatosis. | Molecular pharmacology 20091001 |
| Increased mycophenolic acid exposure in stable kidney transplant recipients on tacrolimus as compared with those on sirolimus: implications for pharmacokinetics. | Clinical pharmacology and therapeutics 20091001 |
| Effects of prostaglandin D2 on Na-dependent phosphate transport activity and its intracellular signaling mechanism in osteoblast-like cells. | Prostaglandins, leukotrienes, and essential fatty acids 20091001 |
| Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes. | American journal of physiology. Renal physiology 20091001 |
| The short-term effect on restenosis and thrombosis of a cobalt-chromium stent eluting two drugs in a porcine coronary artery model. | Journal of interventional cardiology 20091001 |
| Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy. | Biomaterials 20091001 |
| Inhibition of mTOR attenuates store-operated Ca2+ entry in cells from endarterectomized tissues of patients with chronic thromboembolic pulmonary hypertension. | American journal of physiology. Lung cellular and molecular physiology 20091001 |
| AMP-activated protein kinase enhances the expression of muscle-specific ubiquitin ligases despite its activation of IGF-1/Akt signaling in C2C12 myotubes. | Journal of cellular biochemistry 20091001 |
| Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2. | Blood 20091001 |
| Identification of novel autophagy regulators by a luciferase-based assay for the kinetics of autophagic flux. | Autophagy 20091001 |
| Cyclosporine and sirolimus pharmacokinetics and drug-to-drug interactions in kidney transplant recipients. | Fundamental & clinical pharmacology 20091001 |
| Rosiglitazone prevents sirolimus-induced hypomagnesemia, hypokalemia, and downregulation of NKCC2 protein expression. | American journal of physiology. Renal physiology 20091001 |
| Ras pathway activation in hepatocellular carcinoma and anti-tumoral effect of combined sorafenib and rapamycin in vivo. | Journal of hepatology 20091001 |
| Immunosuppressive drugs and Tregs: a critical evaluation! | Clinical journal of the American Society of Nephrology : CJASN 20091001 |
| Expression and mechanism of mammalian target of rapamycin in age-related renal cell senescence and organ aging. | Mechanisms of ageing and development 20091001 |
| Long-term clinical outcomes and stent thrombosis of sirolimus-eluting versus bare metal stents in patients with end-stage renal disease: results of Korean multicenter angioplasty team (KOMATE) Registry. | Journal of interventional cardiology 20091001 |
| Significant association of coronary artery calcification in stent delivery route with restenosis after sirolimus-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20091001 |
| Percutaneous treatment with drug-eluting stent vs bypass surgery in patients suffering from chronic stable angina with multivessel disease involving significant proximal stenosis in left anterior descending artery. | Circulation journal : official journal of the Japanese Circulation Society 20091001 |
| Randomized, non-inferiority trial of three limus agent-eluting stents with different polymer coatings: the Intracoronary Stenting and Angiographic Results: Test Efficacy of 3 Limus-Eluting Stents (ISAR-TEST-4) Trial. | European heart journal 20091001 |
| Sirolimus-containing graft-versus-host disease prophylaxis in patients with lymphoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091001 |
| Dual inhibition of mitogen-activated protein kinase kinase and mammalian target of rapamycin in differentiated and anaplastic thyroid cancer. | The Journal of clinical endocrinology and metabolism 20091001 |
| Involvement of mTORC1 and mTORC2 in regulation of glioblastoma multiforme growth and motility. | International journal of oncology 20091001 |
| Red blood cells carry out T cell growth and survival bioactivities that are sensitive to cyclosporine A. | Cellular and molecular life sciences : CMLS 20091001 |
| Focal brain malformations: seizures, signaling, sequencing. | Epilepsia 20091001 |
| Animal models of focal cortical dysplasia and tuberous sclerosis complex: recent progress toward clinical applications. | Epilepsia 20091001 |
| Combined Bcl-2/mammalian target of rapamycin inhibition leads to enhanced radiosensitization via induction of apoptosis and autophagy in non-small cell lung tumor xenograft model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091001 |
| MYC activity mitigates response to rapamycin in prostate cancer through eukaryotic initiation factor 4E-binding protein 1-mediated inhibition of autophagy. | Cancer research 20091001 |
| Benefits of drug-eluting stents as compared to bare metal stent in ST-segment elevation myocardial infarction: four year results of the PaclitAxel or Sirolimus-Eluting stent vs bare metal stent in primary angiOplasty (PASEO) randomized trial. | American heart journal 20091001 |
| SPIRIT IV trial design: a large-scale randomized comparison of everolimus-eluting stents and paclitaxel-eluting stents in patients with coronary artery disease. | American heart journal 20091001 |
| Significantly lower incidence of early definite stent thrombosis of drug-eluting stents after unrestricted use in Japan using ticlopidine compared to western countries using clopidogrel: a retrospective comparison with western mega-studies. | Journal of cardiology 20091001 |
| A combined, rational approach towards inhibition of the MEK-ERK and mTOR pathways in pancreatic ductal adenocarcinoma: promise or deja vu? | Cancer biology & therapy 20091001 |
| Regulation by FK506 and rapamycin of Ca2+ release from the sarcoplasmic reticulum in vascular smooth muscle: the role of FK506 binding proteins and mTOR. | British journal of pharmacology 20091001 |
| The insulin-like growth factor-1 receptor-targeting antibody, CP-751,871, suppresses tumor-derived VEGF and synergizes with rapamycin in models of childhood sarcoma. | Cancer research 20091001 |
| Conversion from a calcineurin inhibitor to everolimus therapy in maintenance liver transplant recipients: a prospective, randomized, multicenter trial. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091001 |
| Rapamycin inhibits hepatic fibrosis in rats by attenuating multiple profibrogenic pathways. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20091001 |
| Long-term safety and efficacy of sirolimus-eluting stents in Japanese patients: a single-center cohort study. | The Journal of invasive cardiology 20091001 |
| Rotational atherectomy is useful to treat restenosis lesions due to crushing of a sirolimus-eluting stent implanted in severely calcified lesions: experimental study and initial clinical experience. | The Journal of invasive cardiology 20091001 |
| Pentagalloylglucose induces autophagy and caspase-independent programmed deaths in human PC-3 and mouse TRAMP-C2 prostate cancer cells. | Molecular cancer therapeutics 20091001 |
| Relationship between expression of mutant type glutathione S-transferase theta-1 gene and reactivity of rapamycin in myelodysplastic syndrome. | Hematology (Amsterdam, Netherlands) 20091001 |
| Clinical and angiographic outcomes in diabetics from the ENDEAVOR IV trial: randomized comparison of zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease. | JACC. Cardiovascular interventions 20091001 |
| Clinical and angiographic results with the next-generation resolute stent system: a prospective, multicenter, first-in-human trial. | JACC. Cardiovascular interventions 20091001 |
| A generation 2.5 drug-eluting stent? | JACC. Cardiovascular interventions 20091001 |
| Optimal stent-sizing with intravascular ultrasound contributes to complete neointimal coverage after sirolimus-eluting stent implantation assessed by angioscopy. | JACC. Cardiovascular interventions 20091001 |
| Optimal stent expansion and complete neointimal coverage: does this association make sense? | JACC. Cardiovascular interventions 20091001 |
| Current approaches to the use of sirolimus in renal transplantation. | Transplantation proceedings 20091001 |
| Conversion from calcineurin inhibitors to sirolimus in kidney transplant recipients: a retrospective cohort study. | Transplantation proceedings 20091001 |
| Human mesenchymal stem cells and immunosuppressive drug interactions in allogeneic responses: an in vitro study using human cells. | Transplantation proceedings 20091001 |
| [Recent progress in the diagnosis and treatment of aplastic anemia in children]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20091001 |
| [The role of intracellular signal pathway of mTOR/S6 in CD3+ T lymphocytes of refractory/relapsed aplastic anemia patients]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20091001 |
| Effects of combined inhibition of MEK and mTOR on downstream signaling and tumor growth in pancreatic cancer xenograft models. | Cancer biology & therapy 20091001 |
| Treatment of acute myocardial infarction with sirolimus-eluting stents results in chronic endothelial dysfunction in the infarct-related coronary artery. | Circulation. Cardiovascular interventions 20091001 |
| Frontline therapy in mantle cell lymphoma: the role of high-dose therapy and integration of new agents. | Current hematologic malignancy reports 20091001 |
| DISC1 regulates new neuron development in the adult brain via modulation of AKT-mTOR signaling through KIAA1212. | Neuron 20090924 |
| Pore-filling nanoporous templates from degradable block copolymers for nanoscale drug delivery. | ACS nano 20090922 |
| Randomized phase II study comparing two schedules of everolimus in patients with recurrent/metastatic breast cancer: NCIC Clinical Trials Group IND.163. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090920 |
| Triple antiplatelet therapy for clopidogrel resistance with stent malapposition: a case report. | Chinese medical journal 20090920 |
| Genetic alterations in the phosphoinositide 3-kinase/Akt signaling pathway confer sensitivity of thyroid cancer cells to therapeutic targeting of Akt and mammalian target of rapamycin. | Cancer research 20090915 |
| Long-Term outcome of drug-eluting stents compared with bare metal stents in ST-segment elevation myocardial infarction: results of the paclitaxel- or sirolimus-eluting stent versus bare metal stent in Primary Angioplasty (PASEO) Randomized Trial. | Circulation 20090915 |
| Renal cell carcinoma with an emphasis on drug therapy of advanced disease, part 2. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090915 |
| mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells. | Cancer research 20090915 |
| Inhibition of tumor growth progression by antiandrogens and mTOR inhibitor in a Pten-deficient mouse model of prostate cancer. | Cancer research 20090915 |
| Mammalian target of rapamycin inhibition prevents glomerular hypertrophy in a model of renal mass reduction. | Transplantation 20090915 |
| Outcomes with conversion from calcineurin inhibitors to sirolimus after renal transplantation in the context of steroid withdrawal or steroid continuation. | Transplantation 20090915 |
| [Effects of Rapamycin on angiogenesis and tumor progression in human hepatocellular carcinoma implantation mice]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20090915 |
| Sirolimus, bevacizumab, 5-Fluorouracil and irinotecan for advanced colorectal cancer: a pilot study. | World journal of gastroenterology 20090914 |
| Impact of drug-eluting stent selection on long-term clinical outcomes in patients treated for unprotected left main coronary artery disease: the sirolimus vs paclitaxel drug-eluting stent for left main registry (SP-DELFT). | International journal of cardiology 20090911 |
| The Vam6 GEF controls TORC1 by activating the EGO complex. | Molecular cell 20090911 |
| Mutation of a phosphorylatable residue in Put3p affects the magnitude of rapamycin-induced PUT1 activation in a Gat1p-dependent manner. | The Journal of biological chemistry 20090904 |
| mTOR mediates Wnt-induced epidermal stem cell exhaustion and aging. | Cell stem cell 20090904 |
| Ribavirin enhances interferon signaling via stimulation of mTOR and p53 activities. | FEBS letters 20090903 |
| Silent very late thrombotic occlusion of sirolimus-eluting stent confirmed by directional coronary atherectomy. | Circulation journal : official journal of the Japanese Circulation Society 20090901 |
| Effective inhibition of xenografts of hepatocellular carcinoma (HepG2) by rapamycin and bevacizumab in an intrahepatic model. | Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20090901 |
| The effect of rapamycin on bone growth in rabbits. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20090901 |
| Calcineurin inhibitor minimization in pediatric liver allograft recipients. | Pediatric transplantation 20090901 |
| Novel and evolving therapies in the treatment of malignant phaeochromocytoma: experience with the mTOR inhibitor everolimus (RAD001). | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090901 |
| Everolimus restores gefitinib sensitivity in resistant non-small cell lung cancer cell lines. | Biochemical pharmacology 20090901 |
| Molecular mechanisms of pancreatic dysfunction induced by protein malnutrition. | Gastroenterology 20090901 |
| Oral rapamycin reduces tumour burden and vascularization in Lkb1(+/-) mice. | The Journal of pathology 20090901 |
| Monotherapy rapamycin allows an increase of CD4 CD25 FoxP3 T cells in renal recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20090901 |
| S6 kinase 1 knockout inhibits uninephrectomy- or diabetes-induced renal hypertrophy. | American journal of physiology. Renal physiology 20090901 |
| Synergistic effect of rapamycin and cisplatin in endometrial cancer cells. | Cancer 20090901 |
| Sirolimus-related dyspnoea, airway obstruction and pleural effusion after lung transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20090901 |
| Long-term administration of rapamycin reduces adiposity, but impairs glucose tolerance in high-fat diet-fed KK/HlJ mice. | Basic & clinical pharmacology & toxicology 20090901 |
| Calcineurin-mediated GABA(A) receptor dephosphorylation in rats after kainic acid-induced status epilepticus. | Seizure 20090901 |
| Combined targeted treatment to eliminate tumorigenic cancer stem cells in human pancreatic cancer. | Gastroenterology 20090901 |
| Twenty-four months clinical outcomes of sirolimus-eluting stents for the treatment of small coronary arteries: the long-term SES-SMART clinical study. | European heart journal 20090901 |
| Mammalian target of rapamycin inhibitors rapamycin and RAD001 (everolimus) induce anti-proliferative effects in GH-secreting pituitary tumor cells in vitro. | Endocrine-related cancer 20090901 |
| Inhibition of PKHD1 may cause S-phase entry via mTOR signaling pathway. | Cell biology international 20090901 |
| Management of sorafenib, sunitinib, and temsirolimus toxicity in metastatic renal cell carcinoma. | Current opinion in supportive and palliative care 20090901 |
| Rapamycin inhibits hepatectomy-induced stimulation of metastatic tumor growth by reduction of angiogenesis, microvascular blood perfusion, and tumor cell proliferation. | Annals of surgical oncology 20090901 |
| An imbalance in Akt/mTOR is involved in the apoptotic and acantholytic processes in a mouse model of pemphigus vulgaris. | Experimental dermatology 20090901 |
| Successful control of intractable hypoglycemia using rapamycin in an 86-year-old man with a pancreatic insulin-secreting islet cell tumor and metastases. | The Journal of clinical endocrinology and metabolism 20090901 |
| The growing importance of mTORC1-S6K1 signaling in kidney. | American journal of physiology. Renal physiology 20090901 |
| Rapamycin by itself and additively in combination with carboplatin inhibits the growth of ovarian cancer cells. | Gynecologic oncology 20090901 |
| Prophylactic immune tolerance induced by changing the ratio of antigen-specific effector to regulatory T cells. | Journal of thrombosis and haemostasis : JTH 20090901 |
| Rapamycin, the mTOR kinase inhibitor, sensitizes acute myeloid leukemia cells, HL-60 cells, to the cytotoxic effect of arabinozide cytarabine. | Anti-cancer drugs 20090901 |
| Randomised trial of three rapamycin-eluting stents with different coating strategies for the reduction of coronary restenosis: 2-year follow-up results. | Heart (British Cardiac Society) 20090901 |
| A small GTPase, human Rab32, is required for the formation of autophagic vacuoles under basal conditions. | Cellular and molecular life sciences : CMLS 20090901 |
| Quantification of nuclear protein transport using induced heterodimerization. | Traffic (Copenhagen, Denmark) 20090901 |
| Infrapopliteal application of sirolimus-eluting versus bare metal stents for critical limb ischemia: analysis of long-term angiographic and clinical outcome. | Journal of vascular and interventional radiology : JVIR 20090901 |
| Three-year prognosis of Japanese patients with ST-elevation myocardial infarction treated with sirolimus-eluting stents. | Coronary artery disease 20090901 |
| Posttransplantation hypomagnesemia and its relation with immunosuppression as predictors of new-onset diabetes after transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090901 |
| Influence of sirolimus on cyclosporine-induced pancreas islet dysfunction in rats. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090901 |
| Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells. | Journal of autoimmunity 20090901 |
| Rapamycin enhances platelet aggregation induced by adenosine diphosphate in vitro. | Platelets 20090901 |
| Systematic gene expression profile of hypothalamus in calorie-restricted mice implicates the involvement of mTOR signaling in neuroprotective activity. | Mechanisms of ageing and development 20090901 |
| Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signaling. | Nature neuroscience 20090901 |
| CCR5 blockade in combination with rapamycin prolongs cardiac allograft survival in mice. | Clinical and experimental immunology 20090901 |
| Advanced neointimal growth is not associated with a low risk of in-stent thrombus. Optical coherence tomographic findings after first-generation drug-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20090901 |
| CD137 ligand-mediated reverse signals increase cell viability and cytokine expression in murine myeloid cells: involvement of mTOR/p70S6 kinase and Akt. | European journal of immunology 20090901 |
| Increasing longevity through caloric restriction or rapamycin feeding in mammals: common mechanisms for common outcomes? | Aging cell 20090901 |
| Rapamycin activation of 4E-BP prevents parkinsonian dopaminergic neuron loss. | Nature neuroscience 20090901 |
| mTOR is a promising therapeutic target both in cisplatin-sensitive and cisplatin-resistant clear cell carcinoma of the ovary. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090901 |
| Insulin-like growth factor-1 receptor inhibition induces a resistance mechanism via the epidermal growth factor receptor/HER3/AKT signaling pathway: rational basis for cotargeting insulin-like growth factor-1 receptor and epidermal growth factor receptor in hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090901 |
| Concurrent and sequential administration of chemotherapy and the Mammalian target of rapamycin inhibitor temsirolimus in human cancer cells and xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090901 |
| 5-year clinical outcomes after sirolimus-eluting stent implantation insights from a patient-level pooled analysis of 4 randomized trials comparing sirolimus-eluting stents with bare-metal stents. | Journal of the American College of Cardiology 20090901 |
| Rapamycin--rather than FK506--might promote allograft tolerance induced by CD4+CD25+ regulatory T cells. | Surgery 20090901 |
| Images in cardiovascular medicine: Late abnormal vessel wall reaction 3 years after sirolimus-eluting stent implantation. | Circulation 20090901 |
| Very late stent thrombosis of sirolimus-eluting stent combined with late stent malapposition and aneurysm formation. | The Journal of invasive cardiology 20090901 |
| Long-term follow-up after drug eluting stent implantation in left main trifurcations. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901 |
| Bifurcation stenting with drug-eluting stents: a systematic review and meta-analysis of randomised trials. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901 |
| Scanning electron microscopic assessment of the biodegradable coating on expanded biolimus-eluting stents. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090901 |
| Proliferation signal inhibitors for the treatment of refractory autoimmune rheumatic diseases: a new therapeutic option. | Annals of the New York Academy of Sciences 20090901 |
| Early sirolimus therapy in renal transplant recipients at high risk: is it justified? | Transplantation proceedings 20090901 |
| Conversion to sirolimus for chronic allograft nephropathy and calcineurin inhibitor toxicity and the adverse effects of sirolimus after conversion. | Transplantation proceedings 20090901 |
| Impact of vessel size on angiographic and clinical outcomes of revascularization with biolimus-eluting stent with biodegradable polymer and sirolimus-eluting stent with durable polymer the LEADERS trial substudy. | JACC. Cardiovascular interventions 20090901 |
| Effect of balloon inflation time on expansion of sirolimus-eluting stent. | Heart and vessels 20090901 |
| Resolution of late sirolimus-eluting stent thrombosis after tirofiban treatment. | Heart and vessels 20090901 |
| [Bemusement and strategy on the efficacy of clinical application of targeted anticancer drugs]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20090901 |
| [Effect of signal transduction inhibitors on human endometrial carcinoma cells with differential PTEN gene expression]. | Zhonghua fu chan ke za zhi 20090901 |
| [Clinical study of application of sirolimus with dose-reduced or discontinued cyclosporine A for prevention of acute rejection after kidney transplantation]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20090901 |
| Cell signaling. Blocking Akt-ivity. | Science (New York, N.Y.) 20090828 |
| Indirect antitumor effects of mammalian target of rapamycin inhibitors against Kaposi sarcoma in transplant patients. | Transplantation 20090827 |
| Long-term clinical outcomes of sirolimus- versus paclitaxel-eluting stents for patients with unprotected left main coronary artery disease: analysis of the MAIN-COMPARE (revascularization for unprotected left main coronary artery stenosis: comparison of percutaneous coronary angioplasty versus surgical revascularization) registry. | Journal of the American College of Cardiology 20090825 |
| Letter by Movahed regarding article, 'Randomized Study of the Crush Technique Versus Provisional Side-Branch Stenting in True Coronary Bifurcations: The CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study'. | Circulation 20090825 |
| Protein synthesis is resistant to rapamycin and constitutes a promising therapeutic target in acute myeloid leukemia. | Blood 20090820 |
| Sirolimus-eluting stent treatment at high-volume centers confers lower mortality at 6-month follow-up: results from the prospective multicenter German Cypher Registry. | Circulation 20090818 |
| Regulation of autophagy by a beclin 1-targeted microRNA, miR-30a, in cancer cells. | Autophagy 20090816 |
| Targeted inhibition of mammalian target of rapamycin for the treatment of advanced renal cell carcinoma. | Cancer 20090815 |
| Analysis of PTEN and HIF-1alpha and correlation with efficacy in patients with advanced renal cell carcinoma treated with temsirolimus versus interferon-alpha. | Cancer 20090815 |
| Pirfenidone inhibits T-cell activation, proliferation, cytokine and chemokine production, and host alloresponses. | Transplantation 20090815 |
| Minimization of maintenance immunosuppression early after renal transplantation: an interim analysis. | Transplantation 20090815 |
| Increased interleukin-10 production without expansion of CD4+CD25+ T-regulatory cells in early stable renal transplant patients on calcineurin inhibitors. | Transplantation 20090815 |
| Is the intracellular ATP concentration of CD4+ T-Cells a predictive biomarker of immune status in stable transplant recipients? | Transplantation 20090815 |
| Characterization of the rapamycin-sensitive phosphoproteome reveals that Sch9 is a central coordinator of protein synthesis. | Genes & development 20090815 |
| A Rab escort protein integrates the secretion system with TOR signaling and ribosome biogenesis. | Genes & development 20090815 |
| Opposing role of condensin and radiation-sensitive gene RAD52 in ribosomal DNA stability regulation. | The Journal of biological chemistry 20090814 |
| Rapamycin inhibits poly(ADP-ribosyl)ation in intact cells. | Biochemical and biophysical research communications 20090814 |
| Phase III study to evaluate temsirolimus compared with investigator's choice therapy for the treatment of relapsed or refractory mantle cell lymphoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090810 |
| The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesis. | Proceedings of the National Academy of Sciences of the United States of America 20090804 |
| Use of a novel anti-proliferative compound coated on a biopolymer to mitigate platelet-derived growth factor-induced proliferation in human aortic smooth muscle cells: comparison with sirolimus. | Glycoconjugate journal 20090801 |
| Participation of mammalian target of rapamycin complex 1 in Toll-like receptor 2- and 4-induced neutrophil activation and acute lung injury. | American journal of respiratory cell and molecular biology 20090801 |
| Short and long-term benefits of sirolimus-eluting stent in ST-segment elevation myocardial infarction: a meta-analysis of randomized trials. | Journal of thrombosis and thrombolysis 20090801 |
| Sorafenib and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma. | Journal of cellular and molecular medicine 20090801 |
| Rapamycin for focal segmental glomerulosclerosis: a report of 3 cases. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801 |
| Long-term rapamycin therapy in the Han:SPRD rat model of polycystic kidney disease (PKD). | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090801 |
| Clinical impact of sirolimus-eluting stent in ST-segment elevation myocardial infarction: a meta-analysis of randomized clinical trials. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090801 |
| Therapeutic role of sirolimus in non-transplant kidney disease. | Pharmacology & therapeutics 20090801 |
| Everolimus, a promising medical therapy for coronary heart disease? | Medical hypotheses 20090801 |
| Clinical and angiographic outcomes following percutaneous coronary intervention with sirolimus-eluting stents versus bare-metal stents in hemodialysis patients. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801 |
| Gastric mammalian target of rapamycin signaling regulates ghrelin production and food intake. | Endocrinology 20090801 |
| The role of MTOR in mouse uterus during embryo implantation. | Reproduction (Cambridge, England) 20090801 |
| Rapamycin inhibition of the Akt/mTOR pathway blocks select stages of VEGF-A164-driven angiogenesis, in part by blocking S6Kinase. | Arteriosclerosis, thrombosis, and vascular biology 20090801 |
| In vitro interactions between antifungals and immunosuppressive drugs against zygomycetes. | Antimicrobial agents and chemotherapy 20090801 |
| Autophagy is required for extension of yeast chronological life span by rapamycin. | Autophagy 20090801 |
| Effect of rapamycin on cue-induced drug craving in abstinent heroin addicts. | European journal of pharmacology 20090801 |
| Testosterone induces cardiomyocyte hypertrophy through mammalian target of rapamycin complex 1 pathway. | The Journal of endocrinology 20090801 |
| Rapamycin prevents concanavalin A-induced liver injury by inhibiting lymphocyte activation. | Journal of gastroenterology and hepatology 20090801 |
| Clinical grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene: authors' reponse. | The journal of gene medicine 20090801 |
| Posttransplant anemia: the role of sirolimus. | Kidney international 20090801 |
| Infusion of mesenchymal stem cells and rapamycin synergize to attenuate alloimmune responses and promote cardiac allograft tolerance. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090801 |
| Performance of the new mycophenolate assay based on IMPDH enzymatic activity for pharmacokinetic investigations and setup of Bayesian estimators in different populations of allograft recipients. | Therapeutic drug monitoring 20090801 |
| Biochemical, cellular, and in vivo activity of novel ATP-competitive and selective inhibitors of the mammalian target of rapamycin. | Cancer research 20090801 |
| Enhanced interaction between Hsp90 and raptor regulates mTOR signaling upon T cell activation. | Molecular immunology 20090801 |
| Quiz page August 2009: Respiratory distress 5 years after kidney transplantation. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20090801 |
| Are drug-eluting stents safe?: Definitely! Or probably... possibly? Or maybe not yet... | Clinical pharmacology and therapeutics 20090801 |
| A spontaneous acinar cell carcinoma model for monitoring progression of pancreatic lesions and response to treatment through noninvasive bioluminescence imaging. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090801 |
| Comparison of radiosensitizing effects of the mammalian target of rapamycin inhibitor CCI-779 to cisplatin in experimental models of head and neck squamous cell carcinoma. | Molecular cancer therapeutics 20090801 |
| A fractured sirolimus-eluting stent with a coronary aneurysm. | The Annals of thoracic surgery 20090801 |
| Mid-term angiographic benefit of sirolimus-eluting stents compared with paclitaxel-eluting stents in patients with acute myocardial infarction. | Journal of cardiology 20090801 |
| Coronary aneurysm associated with coronary perforation after sirolimus-eluting stents implantation: close follow-up exceeding 2 years by coronary 3-dimensional computed tomography. | Journal of cardiology 20090801 |
| A case of a newly developed yellow neointima at stent implanted site 1 year after sirolimus-eluting stent placement: angioscopic findings. | Journal of cardiology 20090801 |
| Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage. | Hepatology (Baltimore, Md.) 20090801 |
| SES for AMI: moving in the right direction. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090801 |
| Black hole phenomenon observed on IVUS after late restenosis following sirolimus-eluting stent implantation. | The Journal of invasive cardiology 20090801 |
| The effects of sirolimus on urothelial lesions chemically induced in ICR mice by BBN. | Anticancer research 20090801 |
| [Effects of rapamycin on prostate cancer PC-3 cells]. | Ai zheng = Aizheng = Chinese journal of cancer 20090801 |
| Incomplete stent apposition after coronary stent implantation: myth or reality? | Journal of interventional cardiology 20090801 |
| Predictive factors of re-restenosis after repeated sirolimus-eluting stent implantation for SES restenosis and clinical outcomes after percutaneous coronary intervention for SES restenosis. | Journal of interventional cardiology 20090801 |
| Eosinophilic rash secondary to temsirolimus. | Clinical genitourinary cancer 20090801 |
| In-hospital and 1-year outcomes among unselected percutaneous coronary intervention patients treated with either sirolimus- or paclitaxel-eluting stents: results from the EVENT (Evaluation of Drug Eluting Stents and Ischemic Events) registry. | JACC. Cardiovascular interventions 20090801 |
| Angiographic restenosis and clinical recurrence after sirolimus- and paclitaxel-eluting stent implantation. | JACC. Cardiovascular interventions 20090801 |
| Intravascular ultrasound results from the ENDEAVOR IV trial: randomized comparison between zotarolimus- and paclitaxel-eluting stents in patients with coronary artery disease. | JACC. Cardiovascular interventions 20090801 |
| Stent expansion at the segment with thrombus. | JACC. Cardiovascular interventions 20090801 |
| [Effect of rapamycin on leukemia cell lines]. | Zhongguo shi yan xue ye xue za zhi 20090801 |
| Effect of coadministered HIV-protease inhibitors on tacrolimus and sirolimus blood concentrations in a kidney transplant recipient. | Fundamental & clinical pharmacology 20090801 |
| Live fast, die young: new lessons in mammalian longevity. | Rejuvenation research 20090801 |
| Biolimus-eluting biodegradable polymer versus sirolimus-eluting permanent polymer stent performance in long lesions: results from the LEADERS multicentre trial substudy. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090801 |
| Angiographic and intravascular ultrasound findings following implantation of the Endeavor zotarolimus-eluting stents in patients from the real-world clinical practice. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090801 |
| Immunosuppressants: JC virus encephalopathy. Rare but fatal. | Prescrire international 20090801 |
| Novel role for the Saccharomyces cerevisiae oligopeptide transporter Opt2 in drug detoxification. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20090801 |
| [Bronchiolitis obliterans with organizing pneumonia associated with sirolimus in a patient after liver transplantation]. | Revista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva 20090801 |
| Comparison of temsirolimus pharmacokinetics in patients with renal cell carcinoma not receiving dialysis and those receiving hemodialysis: a case series. | Clinical therapeutics 20090801 |
| Two-year clinical, angiographic, and intravascular ultrasound follow-up of the XIENCE V everolimus-eluting stent in the treatment of patients with de novo native coronary artery lesions: the SPIRIT II trial. | Circulation. Cardiovascular interventions 20090801 |
| Contrast enhanced sonography shows superior microvascular renal allograft perfusion in patients switched from cyclosporine A to everolimus. | Transplantation 20090727 |
| The use of intra-coronary optical coherence tomography for the assessment of sirolimus-eluting stent fracture. | International journal of cardiology 20090724 |
| Infectious tolerance via the consumption of essential amino acids and mTOR signaling. | Proceedings of the National Academy of Sciences of the United States of America 20090721 |
| Extracellular matrix binding mixed micelles for drug delivery applications. | Journal of controlled release : official journal of the Controlled Release Society 20090720 |
| Different edge effects of paclitaxel- and sirolimus-eluting stents on proximal and distal edges in patients with unstable angina: serial intravascular ultrasound analysis. | Chinese medical journal 20090720 |
| Rapamycin fed late in life extends lifespan in genetically heterogeneous mice. | Nature 20090716 |
| Ageing: A midlife longevity drug? | Nature 20090716 |
| Comparison of rapamycin- and paclitaxel-eluting stents in patients undergoing primary percutaneous coronary intervention for ST-elevation myocardial infarction. | The American journal of cardiology 20090715 |
| Incidence of delayed graft function and wound healing complications after deceased-donor kidney transplantation is not affected by de novo everolimus. | Transplantation 20090715 |
| Everolimus with reduced cyclosporine versus MMF with standard cyclosporine in de novo heart transplant recipients. | Transplantation 20090715 |
| Comparison of inflammatory response after implantation of sirolimus- and paclitaxel-eluting stents in porcine coronary arteries. | Circulation 20090714 |
| The everolimus-eluting stent in real-world patients: 6-month follow-up of the X-SEARCH (Xience V Stent Evaluated at Rotterdam Cardiac Hospital) registry. | Journal of the American College of Cardiology 20090714 |
| The mTOR pathway is highly activated in diabetic nephropathy and rapamycin has a strong therapeutic potential. | Biochemical and biophysical research communications 20090710 |
| Sirolimus can reverse resistance to gemcitabine, capecitabine and docetaxel combination therapy in pancreatic cancer. | JOP : Journal of the pancreas 20090706 |
| mTOR regulates memory CD8 T-cell differentiation. | Nature 20090702 |
| Immunology: A metabolic switch to memory. | Nature 20090702 |
| RAD001 (everolimus) inhibits tumour growth in xenograft models of human hepatocellular carcinoma. | Journal of cellular and molecular medicine 20090701 |
| Disposition of desipramine, a sensitive cytochrome P450 2D6 substrate, when coadministered with intravenous temsirolimus. | Cancer chemotherapy and pharmacology 20090701 |
| Phospho-mTOR and phospho-4EBP1 in endometrial adenocarcinoma: association with stage and grade in vivo and link with response to rapamycin treatment in vitro. | Journal of cancer research and clinical oncology 20090701 |
| Rapamycin-induced proteinuria following allogeneic hematopoietic stem cell transplantation. | Bone marrow transplantation 20090701 |
| Amniotic membrane transplantation induces apoptosis in T lymphocytes in murine corneas with experimental herpetic stromal keratitis. | Investigative ophthalmology & visual science 20090701 |
| Microarray analyses of the effects of NF-kappaB or PI3K pathway inhibitors on the LPS-induced gene expression profile in RAW264.7 cells: synergistic effects of rapamycin on LPS-induced MMP9-overexpression. | Cellular signalling 20090701 |
| Performance characteristics of a no-pretreatment, random access sirolimus assay for the Dimension RxL clinical chemistry system. | Clinical biochemistry 20090701 |
| Sirolimus-eluting stents, bare metal stents or coronary artery bypass grafting for patients with multivessel disease including involvement of the proximal left anterior descending artery: analysis of the Arterial Revascularization Therapies study part 2 (ARTS-II). | Heart (British Cardiac Society) 20090701 |
| A novel role for the Drosophila epsin (lqf): involvement in autophagy. | Autophagy 20090701 |
| An insight into the mechanistic role of p53-mediated autophagy induction in response to proteasomal inhibition-induced neurotoxicity. | Autophagy 20090701 |
| The pharmacokinetics of mycophenolate mofetil in renal transplant recipients receiving standard-dose or low-dose cyclosporine, low-dose tacrolimus or low-dose sirolimus: the Symphony pharmacokinetic substudy. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701 |
| Long-term clinical and angiographic outcomes after implantation of sirolimus-eluting stents with a 'modified mini-crush' technique in coronary bifurcation lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090701 |
| The incidence and predictors of postprocedural incomplete stent apposition after angiographically successful drug-eluting stent implantation. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090701 |
| RAD001 (Everolimus) induces autophagy in acute lymphoblastic leukemia. | Autophagy 20090701 |
| Practical recommendations for the early use of m-TOR inhibitors (sirolimus) in renal transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20090701 |
| Optimal management of metastatic renal cell carcinoma: an algorithm for treatment. | BJU international 20090701 |
| Rapamycin inhibits mTORC1, but not completely. | Autophagy 20090701 |
| Improved long-term prognosis of elderly women in the era of sirolimus-eluting stents. | Circulation journal : official journal of the Japanese Circulation Society 20090701 |
| Regulation and function of proline oxidase under nutrient stress. | Journal of cellular biochemistry 20090701 |
| Late progression of renal pathology and cyst enlargement is reduced by rapamycin in a mouse model of nephronophthisis. | Kidney international 20090701 |
| Rapamycin enhances LPS induction of tissue factor and tumor necrosis factor-alpha expression in macrophages by reducing IL-10 expression. | Molecular immunology 20090701 |
| FK506 and rapamycin neuroprotect erection and involve different immunophilins in a rat model of cavernous nerve injury. | The journal of sexual medicine 20090701 |
| The impact of everolimus versus mycophenolate on blood and lymphocyte cyclosporine exposure in heart-transplant recipients. | European journal of clinical pharmacology 20090701 |
| Limited sampling strategies for the estimation of sirolimus daily exposure in kidney transplant recipients on a calcineurin inhibitor-free regimen. | Journal of clinical pharmacology 20090701 |
| Rapamycin enhances aplaviroc anti-HIV activity: implications for the clinical development of novel CCR5 antagonists. | Antiviral research 20090701 |
| Effect of autophagy on multiple myeloma cell viability. | Molecular cancer therapeutics 20090701 |
| Considerations in sirolimus use in the early and late post-transplant periods. | Expert opinion on drug safety 20090701 |
| (18)F-FDG and (18)F-FLT uptake early after cyclophosphamide and mTOR inhibition in an experimental lymphoma model. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20090701 |
| The 'mini-crush' technique for managing bifurcation lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090701 |
| Comparison of Tacrolimus and Sirolimus (Tac/Sir) versus Tacrolimus, Sirolimus, and mini-methotrexate (Tac/Sir/MTX) as acute graft-versus-host disease prophylaxis after reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090701 |
| Sirolimus as primary treatment of acute graft-versus-host disease following allogeneic hematopoietic cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090701 |
| Relationship between severity of renal impairment and 2-year outcomes after sirolimus-eluting stent implantation. | American heart journal 20090701 |
| Relationship between neointimal coverage of sirolimus-eluting stents and lesion characteristics: a study with serial coronary angioscopy. | American heart journal 20090701 |
| Transplantation: To convert or not to convert: lessons from the CONVERT trial. | Nature reviews. Nephrology 20090701 |
| 'Rapping' on the door of drug resistance. | Leukemia & lymphoma 20090701 |
| Targeting mammalian target of rapamycin to both downregulate and disable the P-glycoprotein pump in multidrug-resistant B-cell lymphoma cell lines. | Leukemia & lymphoma 20090701 |
| [Renal epithelioid angiomyolipoma]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20090701 |
| Everolimus. | Nature reviews. Drug discovery 20090701 |
| Long-term outcomes comparison of different types of DES in elderly patients from a real-world experience. | The Journal of invasive cardiology 20090701 |
| Defining the optimal treatment for elderly patients: lessons from real-world data. | The Journal of invasive cardiology 20090701 |
| Alefacept promotes co-stimulation blockade based allograft survival in nonhuman primates. | Nature medicine 20090701 |
| [Mammalian target of rapamycin, its mode of action and clinical response in metastatic clear cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20090701 |
| Late stent malapposition with marked positive vascular remodeling observed only at the site of drug-eluting stents after multivessel coronary stenting. | Heart and vessels 20090701 |
| Different vascular response to concurrent implantation of sirolimus- and zotarolimus-eluting stents in the same vessel. | Heart and vessels 20090701 |
| Impact of sex on 3-year outcome after percutaneous coronary intervention using bare-metal and drug-eluting stents in previously untreated coronary artery disease: insights from the RESEARCH (Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital) and T-SEARCH (Taxus-Stent Evaluated at Rotterdam Cardiology Hospital) Registries. | JACC. Cardiovascular interventions 20090701 |
| The efficacy of drug-eluting stents in women: a window of opportunity. | JACC. Cardiovascular interventions 20090701 |
| Population pharmacokinetics of sirolimus in de novo Chinese adult renal transplant patients. | British journal of clinical pharmacology 20090701 |
| [The mTOR inhibitor enhances chemosensitivity of androgen-independent prostate cancer cell line]. | Zhonghua nan ke xue = National journal of andrology 20090701 |
| Use of a cocktail regimen consisting of soluble galectin-1, rapamycin and histone deacetylase inhibitor may effectively prevent type 1 diabetes. | Archives of medical research 20090701 |
| New mTOR inhibitor for renal cell cancer. | Oncology (Williston Park, N.Y.) 20090701 |
| The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1. | Aging 20090701 |
| Overproduction of cyclin D1 is dependent on activated mTORC1 signal in nasopharyngeal carcinoma: implication for therapy. | Cancer letters 20090628 |
| A novel accelerated in vitro release method for biodegradable coating of drug eluting stents: Insight to the drug release mechanisms. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090628 |
| Mesenchymal stem cell and immunosuppressive drug interactions. | Transplantation 20090627 |
| Distribution pattern of neointimal hyperplasia following sirolimus-eluting stent implantation assessed by 3-dimensional intravascular ultrasound. | International journal of cardiology 20090626 |
| GOLPH3 modulates mTOR signalling and rapamycin sensitivity in cancer. | Nature 20090625 |
| Inhibition of the mammalian target of rapamycin signaling pathway suppresses dentate granule cell axon sprouting in a rodent model of temporal lobe epilepsy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090624 |
| Randomized comparison of minimally invasive direct coronary artery bypass surgery versus sirolimus-eluting stenting in isolated proximal left anterior descending coronary artery stenosis. | Journal of the American College of Cardiology 20090623 |
| Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells. | Biochemical and biophysical research communications 20090619 |
| m(en)TOR(ing) differentiating T helper cells. | Immunity 20090619 |
| Sirolimus and everolimus induce endothelial cellular senescence via sirtuin 1 down-regulation: therapeutic implication of cilostazol after drug-eluting stent implantation. | Journal of the American College of Cardiology 20090616 |
| Aging-suppressants: cellular senescence (hyperactivation) and its pharmacologic deceleration. | Cell cycle (Georgetown, Tex.) 20090615 |
| Rapamycin decelerates cellular senescence. | Cell cycle (Georgetown, Tex.) 20090615 |
| Forever young, slim and fit: rapamycin to the rescue. | Cell cycle (Georgetown, Tex.) 20090615 |
| Pharmacologic inhibition of MEK and PI-3K converges on the mTOR/S6 pathway to decelerate cellular senescence. | Cell cycle (Georgetown, Tex.) 20090615 |
| TORC1 controls degradation of the transcription factor Stp1, a key effector of the SPS amino-acid-sensing pathway in Saccharomyces cerevisiae. | Journal of cell science 20090615 |
| Tacrolimus/sirolimus versus tacrolimus/mycophenolate in kidney transplantation: improved 3-year graft and patient survival in recent era. | Transplantation 20090615 |
| Fluvastatin accelerates re-endothelialization impaired by local sirolimus treatment. | European journal of pharmacology 20090610 |
| Biphasic activation of the mTOR pathway in the gustatory cortex is correlated with and necessary for taste learning. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090610 |
| Deregulation of mTOR signaling is involved in thymic lymphoma development in Atm-/- mice. | Biochemical and biophysical research communications 20090605 |
| FDG uptake is a surrogate marker for defining the optimal biological dose of the mTOR inhibitor everolimus in vivo. | British journal of cancer 20090602 |
| Comparison of inflammatory markers and angiographic outcomes after implantation of sirolimus and paclitaxel-eluting stents. | Heart (British Cardiac Society) 20090601 |
| Apoptosis of CD4(+)CD25(high) T cells in response to Sirolimus requires activation of T cell receptor and is modulated by IL-2. | Cancer immunology, immunotherapy : CII 20090601 |
| Polylactide-glycoli acid and rapamycin coating intraocular lens prevent posterior capsular opacification in rabbit eyes. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20090601 |
| Monitoring kidney and renal cyst volumes applying MR approaches on a rapamycin treated mouse model of ADPKD. | Magma (New York, N.Y.) 20090601 |
| High prevalence of ovarian cysts in premenopausal women receiving sirolimus and tacrolimus after clinical islet transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20090601 |
| Rapamycin, but not cyclosporine A, inhibits vascularization and incorporation of implanted surgical meshes. | Transplant international : official journal of the European Society for Organ Transplantation 20090601 |
| Combined inhibition of Dnmt and mTOR signaling inhibits formation and growth of colorectal cancer. | International journal of colorectal disease 20090601 |
| Combination of immunosuppressive drugs leaves specific 'fingerprint' on gene expression in vitro. | Immunopharmacology and immunotoxicology 20090601 |
| Generation of high-yield rapamycin-producing strains through protoplasts-related techniques. | Applied microbiology and biotechnology 20090601 |
| Lung cavitation due to Mycobacterium xenopi in a renal transplant recipient. | Transplant infectious disease : an official journal of the Transplantation Society 20090601 |
| Sirolimus-associated lymphoedema: eight new cases and a proposed mechanism. | The British journal of dermatology 20090601 |
| Intracellular parasitism with Toxoplasma gondii stimulates mammalian-target-of-rapamycin-dependent host cell growth despite impaired signalling to S6K1 and 4E-BP1. | Cellular microbiology 20090601 |
| A phase 2 study with a daily regimen of the oral mTOR inhibitor RAD001 (everolimus) in patients with metastatic clear cell renal cell cancer. | Cancer 20090601 |
| Mammalian target of rapamycin inhibitors and their potential role in therapy in leukaemia and other haematological malignancies. | British journal of haematology 20090601 |
| Rapamycin selectively reduces the association of transcripts containing complex 5' UTRs with ribosomes in C4-2B prostate cancer cells. | Journal of cellular biochemistry 20090601 |
| Immunosuppressive therapy in lung transplantation: state of the art. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20090601 |
| Severe multivessel coronary spasm after sirolimus-eluting stent implantation. | Journal of cardiovascular medicine (Hagerstown, Md.) 20090601 |
| Intervention for jailed diagonal branch is not necessary while stenting the left anterior descending artery. | Journal of interventional cardiology 20090601 |
| Delayed neointimalization on sirolimus-eluting stents: 6-month and 12-month follow up by optical coherence tomography. | Circulation journal : official journal of the Japanese Circulation Society 20090601 |
| Assessment of sirolimus-eluting coronary stent implantation with aspirin plus low dose ticlopidine administration: one year results from CYPHER Stent Japan Post-Marketing Surveillance Registry (J-PMS). | Circulation journal : official journal of the Japanese Circulation Society 20090601 |
| Comparison of low vs moderate dose of atorvastatin in clopidogrel resistance after coronary stenting in Korean patients with acute coronary syndrome. | Circulation journal : official journal of the Japanese Circulation Society 20090601 |
| Phase II randomized study of neoadjuvant everolimus plus letrozole compared with placebo plus letrozole in patients with estrogen receptor-positive breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601 |
| [18F]fluorodeoxyglucose positron emission tomography correlates with Akt pathway activity but is not predictive of clinical outcome during mTOR inhibitor therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090601 |
| Sirolimus as primary immunosuppression is associated with improved coronary vasomotor function compared with calcineurin inhibitors in stable cardiac transplant recipients. | European heart journal 20090601 |
| Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling. | American journal of physiology. Endocrinology and metabolism 20090601 |
| Antagonism of the mammalian target of rapamycin selectively mediates metabolic effects of epidermal growth factor receptor inhibition and protects human malignant glioma cells from hypoxia-induced cell death. | Brain : a journal of neurology 20090601 |
| Expression of mTOR pathway proteins in human amniotic fluid stem cells. | International journal of molecular medicine 20090601 |
| The methylation of the TSC2 promoter underlies the abnormal growth of TSC2 angiomyolipoma-derived smooth muscle cells. | The American journal of pathology 20090601 |
| Black and white: rapamycin as a regulator of cardiac mTOR signaling. | Cell cycle (Georgetown, Tex.) 20090601 |
| Let it be, let it be. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090601 |
| Strategies for drug-eluting stent treatment of bifurcation coronary artery disease in the United States: insights from the e-Cypher S.T.L.L.R.trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090601 |
| Combined inhibition of MEK and mammalian target of rapamycin abolishes phosphorylation of cyclin-dependent kinase 4 in glioblastoma cell lines and prevents their proliferation. | Cancer research 20090601 |
| Improved cardiac function after sirolimus-eluting stent placement in diabetic patients by pioglitazone: combination therapy with statin. | Journal of cardiology 20090601 |
| Absence of proteinuria predicts improvement in renal function after conversion to sirolimus-based immunosuppressive regimens in lung transplant survivors with chronic kidney disease. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090601 |
| Adverse effects of nicotine and immunosuppression on proximal tubular epithelial cell viability, tissue repair and oxidative stress gene expression. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090601 |
| Rapamycin down-regulates inducible nitric oxide synthase by inducing proteasomal degradation. | Biological & pharmaceutical bulletin 20090601 |
| Overexpression of thymosin beta4 increases pseudopodia formation in LNCaP prostate cancer cells. | Biological & pharmaceutical bulletin 20090601 |
| Long-term clinical follow-up after sirolimus-eluting stent versus bare metal stent implantation in patients with acute coronary syndrome. | Journal of interventional cardiology 20090601 |
| Everolimus (RAD001): an mTOR inhibitor for the treatment of metastatic renal cell carcinoma. | Expert review of anticancer therapy 20090601 |
| First-in-man use of polymer-free valsartan-eluting stents in small coronary vessels: a comparison to polymer-free rapamycin (2%)-eluting stents. | Journal of the renin-angiotensin-aldosterone system : JRAAS 20090601 |
| Validation of the type 1 insulin-like growth factor receptor as a therapeutic target in renal cancer. | Molecular cancer therapeutics 20090601 |
| Simultaneous blockade of the epidermal growth factor receptor/mammalian target of rapamycin pathway by epidermal growth factor receptor inhibitors and rapamycin results in reduced cell growth and survival in biliary tract cancer cells. | Molecular cancer therapeutics 20090601 |
| Cyclooxygenase 2 mediates the antiangiogenic effect of rapamycin in Ewing sarcoma. | Journal of pediatric surgery 20090601 |
| Infarct size is increased in female post-MI rats treated with rapamycin. | Canadian journal of physiology and pharmacology 20090601 |
| Impact of stent length on restenosis in patients with acute myocardial infarction treated with primary percutaneous coronary intervention: analysis based on data from the Trial to Assess the Use of the Cypher Stent in Acute Myocardial Infarction Treated with Balloon Angioplasty (TYPHOON). | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601 |
| Reproducibility of quantitative optical coherence tomography for stent analysis. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601 |
| Treatment of refractory chronic urticaria with sirolimus. | Archives of dermatology 20090601 |
| Conversion from calcineurin inhibitors to sirolimus reduces vascularization and thickness of post-transplant cutaneous squamous cell carcinomas. | Anticancer research 20090601 |
| Inhibition of IGF-I receptor signaling in combination with rapamycin or temsirolimus increases MYC-N phosphorylation. | Anticancer research 20090601 |
| The role of antiangiogenesis therapy: bevacizumab and beyond. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20090601 |
| Efficacy of combined inhibition of mTOR and ERK/MAPK pathways in treating a tuberous sclerosis complex cell model. | Journal of genetics and genomics = Yi chuan xue bao 20090601 |
| Impact of target lesion and nontarget lesion cardiac events on 5-year clinical outcomes after sirolimus-eluting or bare-metal stenting. | JACC. Cardiovascular interventions 20090601 |
| The PASEO (PaclitAxel or Sirolimus-Eluting Stent Versus Bare Metal Stent in Primary Angioplasty) Randomized Trial. | JACC. Cardiovascular interventions 20090601 |
| The risk of stent thrombosis in patients with acute coronary syndromes treated with bare-metal and drug-eluting stents. | JACC. Cardiovascular interventions 20090601 |
| Clinical impact of polymorphisms of transport proteins and enzymes involved in the metabolism of immunosuppressive drugs. | Transplantation proceedings 20090601 |
| Long-term follow-up of 100 high-risk renal transplant recipients converted from calcineurin inhibitors to sirolimus: a single center experience. | Transplantation proceedings 20090601 |
| The effect of Malononitrilamides (FK778) on phenotypic properties of human peripheral dendritic cells. | Transplantation proceedings 20090601 |
| Effect of cyclosporine and sirolimus on fatty acid desaturase activities in cultured HEPG2 cells. | Transplantation proceedings 20090601 |
| [Effects of sirolimus on the growth of transplanted hepatocellular carcinoma]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090601 |
| Two-year outcomes of the sirolimus-eluting stent according to unprotected left main lesion. | Clinical cardiology 20090601 |
| [The MULTISTRATEGY study]. | Giornale italiano di cardiologia (2006) 20090601 |
| Decreased acute rejection and improved renal allograft survival using sirolimus and low-dose calcineurin inhibitors without induction therapy. | The International journal of artificial organs 20090601 |
| [Combined rapamycin eye drop in nanometer vector and poly (lactic acid) wafers of cyclosporine A effectively prevents high-risk corneal allograft rejection in rabbits]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20090601 |
| Randomized comparison of the Nobori Biolimus A9-eluting coronary stent with the Taxus Liberté paclitaxel-eluting coronary stent in patients with stenosis in native coronary arteries: the NOBORI 1 trial--Phase 2. | Circulation. Cardiovascular interventions 20090601 |
| Bioabsorbable coronary stents. | Circulation. Cardiovascular interventions 20090601 |
| 'Intracoronary whirling current phenomenon' and thrombus formation after sirolimus-eluting stent implantation visualized by optical coherence tomography. | Circulation. Cardiovascular interventions 20090601 |
| Inhibition of mammalian S6 kinase by resveratrol suppresses autophagy. | Aging 20090601 |
| Three-year clinical outcome of percutaneous treatment of bifurcation lesions in multivessel coronary artery disease with the sirolimus-eluting stent: insights from the Arterial Revascularisation Therapies Study, part II (ARTS II). | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601 |
| Long-term outcome after the V stenting technique in de novo bifurcation lesions using drug-eluting stents. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601 |
| Percutaneous coronary intervention with oral sirolimus and bare metal stents has comparable safety and efficacy to treatment with drug eluting stents, but with significant cost saving: long-term follow-up results from the randomised, controlled ORAR III (Oral Rapamycin in ARgentina) study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090601 |
| Impact of plasma and whole-blood anticoagulant counter ion choice on drug stability and matrix effects during bioanalysis. | Bioanalysis 20090601 |
| Impressive sirolimus-eluting stent fracture immediately after stent implantation: a case report. | International journal of cardiology 20090529 |
| Changes in sodium pump expression dictate the effects of ouabain on cell growth. | The Journal of biological chemistry 20090529 |
| Mammalian target of rapamycin complex 1 (mTORC1) activity is associated with phosphorylation of raptor by mTOR. | The Journal of biological chemistry 20090529 |
| Akt signals through the mammalian target of rapamycin pathway to regulate CNS myelination. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527 |
| The mammalian target of rapamycin signaling pathway mediates epileptogenesis in a model of temporal lobe epilepsy. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090527 |
| [Monitoring and adjustment of immunosuppression after heart transplantation]. | Revue medicale suisse 20090527 |
| Fluorescent probes to characterise FK506-binding proteins. | Chembiochem : a European journal of chemical biology 20090525 |
| Multimodal dynamic imaging of therapeutic biomedical coatings in aqueous medium. | Langmuir : the ACS journal of surfaces and colloids 20090519 |
| Chemopreventive efficacy of rapamycin on Peutz-Jeghers syndrome in a mouse model. | Cancer letters 20090518 |
| Acute myocardial infarction as a consequence of stent fracture and plaque rupture after sirolimus-eluting stent implantation. | International journal of cardiology 20090515 |
| Various optical coherence tomographic findings in restenotic lesions after sirolimus-eluting stent implantation. | International journal of cardiology 20090515 |
| Use of multiple overlapping sirolimus-eluting stents for treatment of long coronary artery lesions: results from a single-center registry in 318 consecutive patients. | International journal of cardiology 20090515 |
| Targeting mTOR in renal cell carcinoma. | Cancer 20090515 |
| Acute liver transplant rejection upon immunosuppression withdrawal in a tolerance induction trial: potential role of IFN-gamma-secreting CD8+ T cells. | Transplantation 20090515 |
| Long-term treatment of sirolimus but not cyclosporine ameliorates diabetic nephropathy in the rat. | Transplantation 20090515 |
| The challenge of achieving target drug concentrations in clinical trials: experience from the Symphony study. | Transplantation 20090515 |
| Disposition of everolimus in mdr1a-/1b- mice and after a pre-treatment of lapatinib in Swiss mice. | Biochemical pharmacology 20090515 |
| Predictors of heightened platelet reactivity despite dual-antiplatelet therapy in patients undergoing percutaneous coronary intervention. | The American journal of cardiology 20090515 |
| Rapamycin prevents early onset of tumorigenesis in an oral-specific K-ras and p53 two-hit carcinogenesis model. | Cancer research 20090515 |
| Paclitaxel- versus sirolimus-eluting stents for unprotected left main coronary artery disease. | Journal of the American College of Cardiology 20090512 |
| Left main coronary artery stenting: crossing the Rubicon. | Journal of the American College of Cardiology 20090512 |
| Regulation of RNA polymerase III transcription involves SCH9-dependent and SCH9-independent branches of the target of rapamycin (TOR) pathway. | The Journal of biological chemistry 20090508 |
| XAP2 inhibits glucocorticoid receptor activity in mammalian cells. | FEBS letters 20090506 |
| A prospective, randomized, 6-month comparison of the coronary vasomotor response associated with a zotarolimus- versus a sirolimus-eluting stent: differential recovery of coronary endothelial dysfunction. | Journal of the American College of Cardiology 20090505 |
| Differences in restenosis rate with different drug-eluting stents in patients with and without diabetes mellitus: a report from the SCAAR (Swedish Angiography and Angioplasty Registry). | Journal of the American College of Cardiology 20090505 |
| Successful treatment of a child having generalized Kaposi's sarcoma after living donor liver transplantation with conversion to sirolimus. | Pediatric transplantation 20090501 |
| Experiences and practical conclusions concerning temsirolimus use and adverse event management in advanced renal cell carcinoma within a compassionate use program in Germany. | Cancer chemotherapy and pharmacology 20090501 |
| Sirolimus inhibits the growth and metastatic progression of hepatocellular carcinoma. | Journal of cancer research and clinical oncology 20090501 |
| PTEN deficiency is a common defect in juvenile myelomonocytic leukemia. | Leukemia research 20090501 |
| Calcineurin inhibitor-free GVHD prophylaxis with sirolimus, mycophenolate mofetil and ATG in Allo-SCT for leukemia patients with high relapse risk: an observational cohort study. | Bone marrow transplantation 20090501 |
| Decrease in sirolimus-induced proteinuria after switch to everolimus in a liver transplant recipient with diabetic nephropathy. | Transplant international : official journal of the European Society for Organ Transplantation 20090501 |
| Impact of clopidogrel resistance on thrombotic events after percutaneous coronary intervention with drug-eluting stent. | Thrombosis research 20090501 |
| Induction of iodide uptake in transformed thyrocytes: a compound screening in cell lines. | European journal of nuclear medicine and molecular imaging 20090501 |
| Suppression of mTOR complex 2-dependent AKT phosphorylation in melanoma cells by combined treatment with rapamycin and LY294002. | The British journal of dermatology 20090501 |
| Ready for a comeback of natural products in oncology. | Biochemical pharmacology 20090501 |
| Differential effects of immunosuppressive drugs on COX-2 activity in vitro and in kidney transplant patients in vivo. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090501 |
| Assaying autophagic activity in transgenic GFP-Lc3 and GFP-Gabarap zebrafish embryos. | Autophagy 20090501 |
| Novel agents for renal cell carcinoma require novel selection paradigms to optimise first-line therapy. | Cancer treatment reviews 20090501 |
| The eIF4E-binding proteins are modifiers of cytoplasmic eIF4E relocalization during the heat shock response. | American journal of physiology. Cell physiology 20090501 |
| LKB1 and AMP-activated protein kinase control of mTOR signalling and growth. | Acta physiologica (Oxford, England) 20090501 |
| Tolerability of first-line therapy for metastatic renal cell carcinoma. | Cancer treatment reviews 20090501 |
| Recent advances in molecular targeted therapy for metastatic renal cell carcinoma. | International journal of urology : official journal of the Japanese Urological Association 20090501 |
| [Targeted therapies and their indications in solid neoplasias]. | La Revue de medecine interne 20090501 |
| Quantitation of selective autophagic protein aggregate degradation in vitro and in vivo using luciferase reporters. | Autophagy 20090501 |
| Comparative healing response after sirolimus- and paclitaxel-eluting stent implantation in a pig model of restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090501 |
| Targeting of mTOR is associated with decreased growth and decreased VEGF expression in acute myeloid leukaemia cells. | European journal of clinical investigation 20090501 |
| Long-term small molecule and protein elution from TiO2 nanotubes. | Nano letters 20090501 |
| Rapamycin reduces high-amplitude, mechanical stretch-induced apoptosis in pulmonary microvascular endothelial cells. | Microvascular research 20090501 |
| Targeting the mTOR signaling network for cancer therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090501 |
| Progress in the treatment of neuroendocrine tumors. | Current oncology reports 20090501 |
| Targeted therapies in metastatic renal cancer in 2009. | BJU international 20090501 |
| Early and limited use of tacrolimus to avoid rejection in an alemtuzumab and sirolimus regimen for kidney transplantation: clinical results and immune monitoring. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090501 |
| Ultra-performance hydrophilic interaction liquid chromatography/tandem mass spectrometry for the determination of everolimus in mouse plasma. | Rapid communications in mass spectrometry : RCM 20090501 |
| Re-restenosis and target lesion revascularization after treatment of sirolimus-eluting stent restenosis: retrospective analysis of 4 Japanese hospitals. | Circulation journal : official journal of the Japanese Circulation Society 20090501 |
| Adenovirus-mediated eukaryotic initiation factor 4E binding protein-1 in combination with rapamycin inhibits tumor growth of pancreatic ductal adenocarcinoma in vivo. | International journal of oncology 20090501 |
| Atg17 recruits Atg9 to organize the pre-autophagosomal structure. | Genes to cells : devoted to molecular & cellular mechanisms 20090501 |
| Efficacy of Xience/promus versus Cypher in rEducing Late Loss after stENTing (EXCELLENT) trial: study design and rationale of a Korean multicenter prospective randomized trial. | American heart journal 20090501 |
| Relationship of deregulated signaling converging onto mTOR with prognosis and classification of lung adenocarcinoma shown by two independent in silico analyses. | Cancer research 20090501 |
| Transplantation: sirolimus plus calcineurin inhibitors in transplantation. | Nature reviews. Nephrology 20090501 |
| New oral treatment for kidney cancer approved. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20090501 |
| Combination of C-reactive protein and cardiac troponin I for predicting adverse cardiac events after sirolimus-eluting stent implantation. | Coronary artery disease 20090501 |
| Recent advances in the chemistry, biosynthesis and pharmacology of rapamycin analogs. | Natural product reports 20090501 |
| Significant response after treatment with the mTOR inhibitor sirolimus in combination with carboplatin and paclitaxel in metastatic melanoma patients. | Journal of the American Academy of Dermatology 20090501 |
| PTEN deficiency is fully penetrant for prostate adenocarcinoma in C57BL/6 mice via mTOR-dependent growth. | The American journal of pathology 20090501 |
| Comparison of medium-term outcomes obtained with drug-eluting stents and coronary artery bypass grafts in an unselected population of diabetic patients with multivessel coronary disease. Propensity score analysis. | Revista espanola de cardiologia 20090501 |
| Beyond monoclonal antibodies: new therapeutic agents in non-Hodgkin's lymphomas. | The oncologist 20090501 |
| Intravascular ultrasound guidance of multiple drug-eluting stent implantation in lesions associated with coronary aneurysms. | The Journal of invasive cardiology 20090501 |
| Percutaneous revascularization of chronic total occlusion of left anterior descending artery using contralateral injection via isolated conus artery. | The Journal of invasive cardiology 20090501 |
| Dual targeting of AKT and mammalian target of rapamycin: a potential therapeutic approach for malignant peripheral nerve sheath tumor. | Molecular cancer therapeutics 20090501 |
| Xience V everolimus-eluting coronary stent. | Expert review of medical devices 20090501 |
| Efficacy on renal function of early conversion from cyclosporine to sirolimus 3 months after renal transplantation: concept study. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090501 |
| The applicability of mTOR inhibition in solid tumors. | Current cancer drug targets 20090501 |
| Atherosclerotic and thrombogenic neointima formed over sirolimus drug-eluting stent: an angioscopic study. | JACC. Cardiovascular imaging 20090501 |
| One step forward and two steps back with drug-eluting-stents: from preventing restenosis to causing late thrombosis and nouveau atherosclerosis. | JACC. Cardiovascular imaging 20090501 |
| Prospective clinical trial comparing two immunosuppressive regimens, tacrolimus and mycophenolate mofetil versus everolimus and low-dose cyclosporine, in de novo renal transplant recipients: results at 6 months follow-up. | Transplantation proceedings 20090501 |
| Cardiovascular risk profile in kidney transplant recipients treated with two immunosuppressive regimens: tacrolimus and mycophenolate mofetil versus everolimus and low-dose cyclosporine. | Transplantation proceedings 20090501 |
| Immunosuppressive agents and metabolic factors of cardiovascular risk in renal transplant recipients. | Transplantation proceedings 20090501 |
| Posttransplant proteinuria associated with everolimus. | Transplantation proceedings 20090501 |
| Immunosuppressive switch to sirolimus in renal dysfunction after liver transplantation. | Transplantation proceedings 20090501 |
| The impact of everolimus on renal function in maintenance liver transplantation. | Transplantation proceedings 20090501 |
| Does everolimus associated with a low dose of cyclosporine in long-term cardiac transplant recipients improve renal function? Initial experience. | Transplantation proceedings 20090501 |
| Rapamycin reduces proteinuria and renal damage in the rat remnant kidney model. | Transplantation proceedings 20090501 |
| 1-year results of the hydroxyapatite polymer-free sirolimus-eluting stent for the treatment of single de novo coronary lesions: the VESTASYNC I trial. | JACC. Cardiovascular interventions 20090501 |
| A randomized optical coherence tomography study of coronary stent strut coverage and luminal protrusion with rapamycin-eluting stents. | JACC. Cardiovascular interventions 20090501 |
| Incomplete stent apposition and delayed tissue coverage are more frequent in drug-eluting stents implanted during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction than in drug-eluting stents implanted for stable/unstable angina: insights from optical coherence tomography. | JACC. Cardiovascular interventions 20090501 |
| Local determinants of thrombus formation following sirolimus-eluting stent implantation assessed by optical coherence tomography. | JACC. Cardiovascular interventions 20090501 |
| From a foggy sight to a clear vision. | JACC. Cardiovascular interventions 20090501 |
| Biodegradable polymer films for releasing nanovehicles containing sirolimus. | Drug delivery 20090501 |
| [Drug-eluting stents - new standard of restenosis treatment]. | Kardiologia polska 20090501 |
| Combined therapy of CD4(+)CD25(+) regulatory T cells with low-dose sirolimus, but not calcineurin inhibitors, preserves suppressive function of regulatory T cells and prolongs allograft survival in mice. | International immunopharmacology 20090501 |
| In vitro induced CD4(+)CD25(+)Foxp3(+) Tregs attenuate hepatic ischemia-reperfusion injury. | International immunopharmacology 20090501 |
| [Intravascular ultrasound assessment of sirolimus-eluting stent restenosis or thrombosis after stent implantation]. | Zhonghua xin xue guan bing za zhi 20090501 |
| Five-year follow-up after sirolimus-eluting stent implantation results of the SIRIUS (Sirolimus-Eluting Stent in De-Novo Native Coronary Lesions) Trial. | Journal of the American College of Cardiology 20090428 |
| Sirolimus in kidney transplantation indications and practical guidelines: de novo sirolimus-based therapy without calcineurin inhibitors. | Transplantation 20090427 |
| Sirolimus-based therapy for kidney transplantation from expanded criteria donors. | Transplantation 20090427 |
| Minimizing the risk of posttransplant malignancy. | Transplantation 20090427 |
| Management of side effects of sirolimus therapy. | Transplantation 20090427 |
| Inhibitors of the mammalian target of rapamycin and transplant tolerance. | Transplantation 20090427 |
| Review of symposium. Sirolimus in kidney transplantation. | Transplantation 20090427 |
| Protocol conversion from a calcineurin inhibitor based therapy to sirolimus. | Transplantation 20090427 |
| Rapamycin-eluting stents in the arterial duct: experimental observations in the pig model. | Circulation 20090421 |
| Focus Issue: demystifying mTOR signaling. | Science signaling 20090421 |
| The pharmacology of mTOR inhibition. | Science signaling 20090421 |
| Immune regulation by rapamycin: moving beyond T cells. | Science signaling 20090421 |
| Frequency, predictors and outcome of stent fracture after sirolimus-eluting stent implantation. | International journal of cardiology 20090417 |
| Gene expression patterns in mismatch repair-deficient colorectal cancers highlight the potential therapeutic role of inhibitors of the phosphatidylinositol 3-kinase-AKT-mammalian target of rapamycin pathway. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090415 |
| Efficacy of systemically administered oncolytic vaccinia virotherapy for malignant gliomas is enhanced by combination therapy with rapamycin or cyclophosphamide. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090415 |
| Serial intravascular ultrasound analysis of peri-stent remodeling and proximal and distal edge effects after sirolimus-eluting or paclitaxel-eluting stent implantation in patients with diabetes mellitus. | The American journal of cardiology 20090415 |
| Activating transcription factor 4 and CCAAT/enhancer-binding protein-beta negatively regulate the mammalian target of rapamycin via Redd1 expression in response to oxidative and endoplasmic reticulum stress. | Free radical biology & medicine 20090415 |
| Sirolimus to replace calcineurin inhibitors? Too early yet. | Lancet (London, England) 20090411 |
| Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia. | Blood 20090402 |
| The role of mTOR in the management of solid tumors: an overview. | Cancer treatment reviews 20090401 |
| Comparison of changes in early inflammatory markers between sirolimus- and paclitaxel-eluting stent implantation. | Cardiovascular drugs and therapy 20090401 |
| Safe conversion of mycophenolate mofetil to azathioprine in kidney transplant recipients with sirolimus-based immunosuppression. | Nephrology (Carlton, Vic.) 20090401 |
| The evaluation of primary stenting of sirolimus-eluting versus bare-metal stents in the treatment of atherosclerotic lesions of crural arteries. | European radiology 20090401 |
| S6K1 is involved in polyploidization through its phosphorylation at Thr421/Ser424. | Journal of cellular physiology 20090401 |
| Early systemic inflammatory response to drug-eluting stents implantation: the heart of the difference? Editorial to: 'Comparison of changes in early inflammatory markers between sirolimus- and paclitaxel-eluting stent implantation' by Li et al. | Cardiovascular drugs and therapy 20090401 |
| Role of the Botrytis cinerea FKBP12 ortholog in pathogenic development and in sulfur regulation. | Fungal genetics and biology : FG & B 20090401 |
| Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice. | Diabetes 20090401 |
| Rapamycin reduces seizure frequency in tuberous sclerosis complex. | Journal of child neurology 20090401 |
| Everolimus and sirolimus antagonize tacrolimus based calcineurin inhibition via competition for FK-binding protein 12. | Biochemical pharmacology 20090401 |
| Autophagy in coxsackievirus-infected neurons. | Autophagy 20090401 |
| Relevance of cytotoxic alloreactivity under different immunosuppressive regimens in clinical islet cell transplantation. | Clinical and experimental immunology 20090401 |
| Uremic cardiac hypertrophy is reversed by rapamycin but not by lowering of blood pressure. | Kidney international 20090401 |
| The prolyl isomerase Pin1 interacts with a ribosomal protein S6 kinase to enhance insulin-induced AP-1 activity and cellular transformation. | Carcinogenesis 20090401 |
| Correlation between quantitative angiographic and intravascular ultrasound parameters in patients treated with sirolimus analogous-eluting stents. | The international journal of cardiovascular imaging 20090401 |
| Rapamycin administration in humans blocks the contraction-induced increase in skeletal muscle protein synthesis. | The Journal of physiology 20090401 |
| Both tacrolimus and sirolimus decrease Th1/Th2 ratio, and increase regulatory T lymphocytes in the liver after ischemia/reperfusion. | Laboratory investigation; a journal of technical methods and pathology 20090401 |
| Amino acid-sensing mTOR signaling is involved in modulation of lipolysis by chronic insulin treatment in adipocytes. | American journal of physiology. Endocrinology and metabolism 20090401 |
| PI3K and mTOR inhibitors: a new generation of targeted anticancer agents. | Current opinion in cell biology 20090401 |
| Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome. | British journal of haematology 20090401 |
| Differential control of allo-antigen-specific regulatory T cells and effector T cells by anti-CD4 and other agents in establishing transplantation tolerance. | International immunology 20090401 |
| Tubers and tumors: rapamycin therapy for benign and malignant tumors. | Current opinion in cell biology 20090401 |
| A polymer-free dual drug-eluting stent in patients with coronary artery disease: a randomized trial vs. polymer-based drug-eluting stents. | European heart journal 20090401 |
| Myeloma cell growth inhibition is augmented by synchronous inhibition of the insulin-like growth factor-1 receptor by NVP-AEW541 and inhibition of mammalian target of rapamycin by Rad001. | Anti-cancer drugs 20090401 |
| Comparison of the systemic levels of inflammatory markers after percutaneous coronary intervention with bare metal versus sirolimus-eluting stents. | Journal of interventional cardiology 20090401 |
| Repetitive stretch suppresses denervation-induced atrophy of soleus muscle in rats. | Muscle & nerve 20090401 |
| Targeting mTOR with rapamycin: one dose does not fit all. | Cell cycle (Georgetown, Tex.) 20090401 |
| Combining sirolimus-eluting stents and external irradiation in cholesterol-fed rabbits increased incomplete stent apposition and decreased re-endothelialization. | Journal of cardiovascular pharmacology 20090401 |
| Novel neointimal formation over sirolimus-eluting stents identified by coronary angioscopy and optical coherence tomography. | Journal of cardiology 20090401 |
| A qualitative and quantitative angiographic analysis of stent fracture late following sirolimus-eluting stent implantation. | The American journal of cardiology 20090401 |
| One-year outcomes from the TAXUS express stent versus cypher stent. | The American journal of cardiology 20090401 |
| Sirolimus and mTORC1: centre stage in the story of what makes muscles bigger? | The Journal of physiology 20090401 |
| Management of chronic allograft nephropathy: a systematic review. | Clinical journal of the American Society of Nephrology : CJASN 20090401 |
| No major neurologic complications with sirolimus use in heart transplant recipients. | Mayo Clinic proceedings 20090401 |
| The HER-2 receptor and breast cancer: ten years of targeted anti-HER-2 therapy and personalized medicine. | The oncologist 20090401 |
| Neuroendocrine tumors: nursing implications for oral targeted agents and patient management: Part II. | Clinical journal of oncology nursing 20090401 |
| Critical role for hypothalamic mTOR activity in energy balance. | Cell metabolism 20090401 |
| The toxicities of modern targeted therapies: learning from the price of progress. | Targeted oncology 20090401 |
| Zotarolimus for the treatment of coronary artery disease: pathophysiology, DES design, clinical evaluation and future perspective. | Expert opinion on pharmacotherapy 20090401 |
| Increased AKT S473 phosphorylation after mTORC1 inhibition is rictor dependent and does not predict tumor cell response to PI3K/mTOR inhibition. | Molecular cancer therapeutics 20090401 |
| Targeting melanoma with dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitors. | Molecular cancer research : MCR 20090401 |
| Rapamycin protects against high fat diet-induced obesity in C57BL/6J mice. | Journal of pharmacological sciences 20090401 |
| Prospects for mTOR targeting in adult T cell leukemia. | Leukemia & lymphoma 20090401 |
| Rapamycin and curcumin induce apoptosis in primary resting B chronic lymphocytic leukemia cells. | Leukemia & lymphoma 20090401 |
| mTOR inhibition and adult T-cell leukemia. | Leukemia & lymphoma 20090401 |
| Targeting the mTOR pathway using deforolimus in cancer therapy. | Future oncology (London, England) 20090401 |
| Hypertension induced by immunosuppressive drugs: a comparative analysis between sirolimus and cyclosporine. | Transplantation proceedings 20090401 |
| Sirolimus in pediatric liver transplantation: a single-center experience. | Transplantation proceedings 20090401 |
| Sirolimus-induced drug fever in a renal transplant patient: a case report. | Transplantation proceedings 20090401 |
| Mucosa-associated lymphoid tissue gastric lymphoma regression in a renal transplant patient after conversion of the immunosuppression to sirolimus: a case report. | Transplantation proceedings 20090401 |
| Safety of an immunosuppressant protocol based on sirolimus in liver transplant recipients with malignancies or high risk of tumor recurrence. | Transplantation proceedings 20090401 |
| Right adrenal metastases of hepatocarcinoma after liver transplantation: case report and literature review. | Transplantation proceedings 20090401 |
| mTOR in renal cell cancer: modulator of tumor biology and therapeutic target. | Expert review of molecular diagnostics 20090401 |
| Novel side branch ostial stent. | Journal of interventional cardiology 20090401 |
| [Effect of rapamycin on proliferation, apoptosis and regulation of chemokine receptor CXCR4 in RPMI8226 cells]. | Zhongguo shi yan xue ye xue za zhi 20090401 |
| The emerging safety profile of mTOR inhibitors, a novel class of anticancer agents. | Targeted oncology 20090401 |
| Drug-eluting stents versus bare-metal stents in diabetic patients with ST-segment elevation acute myocardial infarction: a pooled analysis of individual patient data from seven randomized trials. | Revista espanola de cardiologia 20090401 |
| RAD001 (Everolimus) Can prevent tamoxifen-related endometrial and stromal hyperplasia. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090401 |
| Rapamycin effects on mTOR signaling in benign, premalignant and malignant human breast epithelial cells. | Anticancer research 20090401 |
| Treatment for the recurrence of hepatocellular carcinoma following liver transplantation: what is the best strategy? | Cancer biology & therapy 20090401 |
| Cost-effectiveness of the real-world use of drug-eluting stents at 9-month follow-up: results from the Sicilian DES Registry. | Journal of cardiovascular medicine (Hagerstown, Md.) 20090401 |
| Lowering the dose of sirolimus, released from a nonpolymeric hydroxyapatite coated coronary stent, reduces signs of delayed healing. | JACC. Cardiovascular interventions 20090401 |
| Durability of antirestenotic efficacy in drug-eluting stents with and without permanent polymer. | JACC. Cardiovascular interventions 20090401 |
| Temporal course of neointimal formation after drug-eluting stent placement: is our understanding of restenosis changing? | JACC. Cardiovascular interventions 20090401 |
| Safety and efficacy of biodegradable polymer-coated sirolimus-eluting stents in 'real-world' practice: 18-month clinical and 9-month angiographic outcomes. | JACC. Cardiovascular interventions 20090401 |
| The excel stent: a good DES, but can we really stop clopidogrel after 6 months? | JACC. Cardiovascular interventions 20090401 |
| Rare diseases offer insights into autism spectrum disorders. Preliminary laboratory studies suggest new biological targets for intervention. | The Harvard mental health letter 20090401 |
| Drug-eluting coronary stents: many meta-analyses, little benefit. | Prescrire international 20090401 |
| Frequency and clinical consequences associated with sidebranch occlusion during stent implantation using zotarolimus-eluting and paclitaxel-eluting coronary stents. | Circulation. Cardiovascular interventions 20090401 |
| Sfp1 interaction with TORC1 and Mrs6 reveals feedback regulation on TOR signaling. | Molecular cell 20090327 |
| 9-month clinical, angiographic, and intravascular ultrasound results of a prospective evaluation of the Axxess self-expanding biolimus A9-eluting stent in coronary bifurcation lesions: the DIVERGE (Drug-Eluting Stent Intervention for Treating Side Branches Effectively) study. | Journal of the American College of Cardiology 20090324 |
| Molecular events in the activation of B cells and macrophages by a non-microbial TLR4 agonist, G1-4A from Tinospora cordifolia. | Immunology letters 20090324 |
| mTORC1 activation regulates beta-cell mass and proliferation by modulation of cyclin D2 synthesis and stability. | The Journal of biological chemistry 20090320 |
| An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1. | The Journal of biological chemistry 20090320 |
| Evaluation of neointimal coverage of overlapping sirolimus-eluting stents by optical coherence tomography. | Chinese medical journal 20090320 |
| Long-term clinical outcomes after bioabsorbable polymer- and durable polymer-based sirolimus-eluting stents implantation: two-year follow-up results from a large single-center database. | Chinese medical journal 20090320 |
| Obesity increases vascular senescence and susceptibility to ischemic injury through chronic activation of Akt and mTOR. | Science signaling 20090317 |
| Aberrant hyperactivation of akt and Mammalian target of rapamycin complex 1 signaling in sporadic chordomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090315 |
| CDC25B mediates rapamycin-induced oncogenic responses in cancer cells. | Cancer research 20090315 |
| A novel JAK3 inhibitor, R348, attenuates chronic airway allograft rejection. | Transplantation 20090315 |
| Mycophenolate and sirolimus as calcineurin inhibitor-free immunosuppression improves renal function better than calcineurin inhibitor-reduction in late cardiac transplant recipients with chronic renal failure. | Transplantation 20090315 |
| A bioabsorbable everolimus-eluting coronary stent system (ABSORB): 2-year outcomes and results from multiple imaging methods. | Lancet (London, England) 20090314 |
| Clinical outcome of patients with chronic total occlusion treated with drug-eluting stents. | International journal of cardiology 20090306 |
| S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation. | The Journal of biological chemistry 20090306 |
| Rapamycin induces transactivation of the EGFR and increases cell survival. | Oncogene 20090305 |
| Targeting mTOR: something old, something new. | Journal of the National Cancer Institute 20090304 |
| A randomized comparison of sirolimus- versus paclitaxel-eluting stent implantation in patients with diabetes mellitus 2-year clinical outcomes of the DES-DIABETES trial. | Journal of the American College of Cardiology 20090303 |
| Nanoscale mechanical measurement determination of the glass transition temperature of poly(lactic acid)/everolimus coated stents in air and dissolution media. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090302 |
| Phosphorylation of p70S6 kinase predicts overall survival in patients with clear margin-resected hepatocellular carcinoma. | Liver international : official journal of the International Association for the Study of the Liver 20090301 |
| The effect of switching from calcineurin inhibitor to sirolimus on the incidence of skin cancers in kidney transplant recipients. | Journal of the European Academy of Dermatology and Venereology : JEADV 20090301 |
| Activation of interleukin-6/STAT3 in rat cholangiocyte proliferation induced by lipopolysaccharide. | Digestive diseases and sciences 20090301 |
| A pilot trial of the mTOR (mammalian target of rapamycin) inhibitor RAD001 in patients with advanced B-CLL. | Annals of hematology 20090301 |
| Sirolimus as a potential radiosensitizer in squamous cell cancer of the head and neck. | Head & neck 20090301 |
| Negative vascular remodelling after implantation of bioabsorbable magnesium alloy stents in porcine coronary arteries: a randomised comparison with bare-metal and sirolimus-eluting stents. | Heart (British Cardiac Society) 20090301 |
| Hypersensitivity of Ph-positive lymphoid cell lines to rapamycin: Possible clinical application of mTOR inhibitor. | Leukemia research 20090301 |
| Liquid chromatographic method for the determination of sirolimus in blood using electrochemical detection. | Biomedical chromatography : BMC 20090301 |
| A pilot study of everolimus and gefitinib in the treatment of recurrent glioblastoma (GBM). | Journal of neuro-oncology 20090301 |
| Factors associated with proteinuria in renal transplant recipients treated with sirolimus. | Transplant international : official journal of the European Society for Organ Transplantation 20090301 |
| Conversion to everolimus monotherapy in maintenance liver transplantation: feasibility, safety, and impact on renal function. | Transplant international : official journal of the European Society for Organ Transplantation 20090301 |
| Sirolimus monotherapy effectiveness in liver transplant recipients with renal dysfunction due to calcineurin inhibitors. | Journal of clinical gastroenterology 20090301 |
| Rapamycin inhibits in vitro growth and release of angiogenetic factors in human bladder cancer. | Urology 20090301 |
| Nitrogen catabolite repression-sensitive transcription as a readout of Tor pathway regulation: the genetic background, reporter gene and GATA factor assayed determine the outcomes. | Genetics 20090301 |
| Immunoregulatory profiles in liver transplant recipients on different immunosuppressive agents. | Human immunology 20090301 |
| Stimulation of skeletal muscle myofibrillar protein synthesis, p70 S6 kinase phosphorylation, and ribosomal protein S6 phosphorylation by inhibition of myostatin in mature mice. | American journal of physiology. Endocrinology and metabolism 20090301 |
| Angiographic patterns of restenosis after sirolimus-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20090301 |
| Everolimus attenuates neointimal hyperplasia in cultured human saphenous vein grafts. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20090301 |
| Treatment of severe aplastic anemia with a combination of horse antithymocyte globulin and cyclosporine, with or without sirolimus: a prospective randomized study. | Haematologica 20090301 |
| Combined inhibition of MEK and mTOR signaling inhibits initiation and progression of colorectal cancer. | Cancer investigation 20090301 |
| Effects of oral posaconazole on the pharmacokinetics of sirolimus. | Current medical research and opinion 20090301 |
| Low-dose oral sirolimus reduces atherogenesis, vascular inflammation and modulates plaque composition in mice lacking the LDL receptor. | British journal of pharmacology 20090301 |
| Trypanosome TOR complex 2 functions in cytokinesis. | Cell cycle (Georgetown, Tex.) 20090301 |
| mTOR inhibitor RAD001 (everolimus) has antiangiogenic/vascular properties distinct from a VEGFR tyrosine kinase inhibitor. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090301 |
| Phospho-p70S6K/p85S6K and cdc2/cdk1 are novel targets for diffuse large B-cell lymphoma combination therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090301 |
| Percutaneous coronary intervention for a right coronary artery stent occlusion using retrograde delivery of a sirolimus-eluting stent via a septal perforator. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090301 |
| Value of drug-eluting stents in cardiac transplant recipients. | The American journal of cardiology 20090301 |
| Oral rapamycin attenuates inflammation and enhances stability of atherosclerotic plaques in rabbits independent of serum lipid levels. | British journal of pharmacology 20090301 |
| Determination of blood sirolimus concentrations in liver and kidney transplant recipients using the Innofluor fluorescence polarization immunoassay: comparison with the microparticle enzyme immunoassay and high-performance liquid chromatography-ultraviolet method. | Upsala journal of medical sciences 20090301 |
| Immunosuppressive treatment for aplastic anemia: are we hitting the ceiling? | Haematologica 20090301 |
| Autophagy enhances the efficacy of BCG vaccine by increasing peptide presentation in mouse dendritic cells. | Nature medicine 20090301 |
| Recommendations from the Spanish Oncology Genitourinary Group for the treatment of metastatic renal cancer. | Cancer chemotherapy and pharmacology 20090301 |
| ID2-VEGF-related pathways in the pathogenesis of Kaposi's sarcoma: a link disrupted by rapamycin. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090301 |
| Using the stochastic collocation method for the uncertainty quantification of drug concentration due to depot shape variability. | IEEE transactions on bio-medical engineering 20090301 |
| Recent advances in the systemic treatment of metastatic papillary renal cancer. | Expert review of anticancer therapy 20090301 |
| Inhibition of Janus kinase 2 and signal transduction and activator of transcription 3 protect against cecal ligation and puncture-induced multiple organ damage and mortality. | The Journal of trauma 20090301 |
| Drug exposure and perceived adverse drug events reported by liver-transplant patients. | International journal of clinical pharmacology and therapeutics 20090301 |
| Safety and efficacy of 2.5-mm sirolimus-eluting stent implantation at lower deployment pressures in very small vessels (<2.5 mm). | Coronary artery disease 20090301 |
| Prolonged dual antiplatelet therapy improves clinical outcomes in high-risk patients implanted with sirolimus-eluting stents. | Clinical cardiology 20090301 |
| Late conversion from calcineurin inhibitor-based to sirolimus-based immunosuppression due to chronic toxicity: a prospective study with protocol biopsy amendment. | Transplantation proceedings 20090301 |
| [Prevention of hepatic tumor growth and metastasis in rats with rapamycin]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090301 |
| Incidence of stent thrombosis in patients with drug eluting stents and short-term dual antiplatelet therapy. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090301 |
| Re-examining minimal luminal diameter relocation and quantitative coronary angiography--intravascular ultrasound correlations in stented saphenous vein grafts: methodological insights from the randomised RRISC trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090301 |
| Advances in the pathogenesis and treatment of polycystic kidney disease. | Current opinion in nephrology and hypertension 20090301 |
| Mini-crush versus T-provisional techniques in bifurcation lesions: clinical and angiographic long-term outcome after implantation of drug-eluting stents. | JACC. Cardiovascular interventions 20090301 |
| [Lymphoproliferative disorders after renal transplantation in a child]. | Revista medica de Chile 20090301 |
| Paclitaxel versus sirolimus stents in diabetic and nondiabetic patients. | Circulation. Cardiovascular quality and outcomes 20090301 |
| Validation of anti-aging drugs by treating age-related diseases. | Aging 20090301 |
| Target of rapamycin (TOR) mediates the transduction of nutritional signals into juvenile hormone production. | The Journal of biological chemistry 20090227 |
| Progression of renal dysfunction in cardiac transplantation after the introduction of everolimus in the immunosuppressive regime. | Transplantation 20090227 |
| Antiplatelet therapy and stent thrombosis after sirolimus-eluting stent implantation. | Circulation 20090224 |
| 2-year clinical outcomes after implantation of sirolimus-eluting, paclitaxel-eluting, and bare-metal coronary stents: results from the WDHR (Western Denmark Heart Registry). | Journal of the American College of Cardiology 20090224 |
| Paclitaxel versus sirolimus: the battle is still ongoing. | Journal of the American College of Cardiology 20090224 |
| Highly diastereoselective desymmetrisation of cyclic meso-anhydrides and derivatisation for use in natural product synthesis. | Organic & biomolecular chemistry 20090221 |
| Zebrafish Tsc1 reveals functional interactions between the cilium and the TOR pathway. | Human molecular genetics 20090215 |
| T cell dependence on mTOR signaling. | Cell cycle (Georgetown, Tex.) 20090215 |
| Evaluation of mTOR function by a gain-of-function approach. | Cell cycle (Georgetown, Tex.) 20090215 |
| Marked activity of irinotecan and rapamycin combination toward colon cancer cells in vivo and in vitro is mediated through cooperative modulation of the mammalian target of rapamycin/hypoxia-inducible factor-1alpha axis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090215 |
| Not all substrates are treated equally: implications for mTOR, rapamycin-resistance and cancer therapy. | Cell cycle (Georgetown, Tex.) 20090215 |
| Activation of mammalian target of rapamycin controls the loss of TCRzeta in lupus T cells through HRES-1/Rab4-regulated lysosomal degradation. | Journal of immunology (Baltimore, Md. : 1950) 20090215 |
| Long-term outcomes of left main coronary intervention with drug-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090215 |
| Long-term clinical outcomes after drug-eluting stent implantation in unprotected left main coronary artery disease. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090215 |
| AKT/mTOR pathway activation and BCL-2 family proteins modulate the sensitivity of human small cell lung cancer cells to RAD001. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090215 |
| A phase I trial to determine the safety, tolerability, and maximum tolerated dose of deforolimus in patients with advanced malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090215 |
| Pharmacological inhibition of mTORC1 suppresses anatomical, cellular, and behavioral abnormalities in neural-specific Pten knock-out mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090211 |
| Delivery of rapamycin to dendritic cells using degradable microparticles. | Journal of controlled release : official journal of the Controlled Release Society 20090210 |
| Randomized comparison of everolimus-eluting and paclitaxel-eluting stents: two-year clinical follow-up from the Clinical Evaluation of the Xience V Everolimus Eluting Coronary Stent System in the Treatment of Patients with de novo Native Coronary Artery Lesions (SPIRIT) III trial. | Circulation 20090210 |
| Coronary stent strut fracture after drug-eluting stent implantation: a newly recognized complication. | International journal of cardiology 20090206 |
| Investigation of the regulation of transcriptional changes in Ancylostoma caninum larvae following serum activation, with a focus on the insulin-like signalling pathway. | Veterinary parasitology 20090205 |
| Characterization of sirolimus metabolites in pediatric solid organ transplant recipients. | Pediatric transplantation 20090201 |
| Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells. | European journal of medicinal chemistry 20090201 |
| Complex functions of phosphatidylinositol 4,5-bisphosphate in regulation of TRPC5 cation channels. | Pflugers Archiv : European journal of physiology 20090201 |
| Rapamycin in islet transplantation: friend or foe? | Transplant international : official journal of the European Society for Organ Transplantation 20090201 |
| Adenovirus-mediated FKBP12.6 overexpression induces hypertrophy and apoptosis in cultured neonatal cardiomyocytes. | Clinical and experimental pharmacology & physiology 20090201 |
| Sirolimus interacts with pathways essential for podocyte integrity. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201 |
| The pre-clinical assessment of rapamycin-eluting, durable polymer-free stent coating concepts. | Biomaterials 20090201 |
| Sphingosine-1-phosphate induced mTOR-activation is mediated by the E3-ubiquitin ligase PAM. | Cellular signalling 20090201 |
| IGF-I, EGF, and sex steroids regulate autophagy in bovine mammary epithelial cells via the mTOR pathway. | European journal of cell biology 20090201 |
| Activation of the mammalian target of rapamycin signalling pathway in epidermal tumours and its correlation with cyclin-dependent kinase 2. | The British journal of dermatology 20090201 |
| mTOR regulates expression of slit diaphragm proteins and cytoskeleton structure in podocytes. | American journal of physiology. Renal physiology 20090201 |
| Inhibitory effect of rapamycin and dexamethasone on production of IL-17 and IFN-gamma in Vogt-Koyanagi-Harada patients. | The British journal of ophthalmology 20090201 |
| Everolimus inhibits monocyte/macrophage migration in vitro and their accumulation in carotid lesions of cholesterol-fed rabbits. | The Journal of pharmacology and experimental therapeutics 20090201 |
| Recent advances in neurobiology of Tuberous Sclerosis Complex. | Brain & development 20090201 |
| The autophagic induction in Helicobacter pylori-infected macrophage. | Experimental biology and medicine (Maywood, N.J.) 20090201 |
| Robust, high-throughput LC-MS/MS method for therapeutic drug monitoring of cyclosporine, tacrolimus, everolimus, and sirolimus in whole blood. | Therapeutic drug monitoring 20090201 |
| Preventing the unfolded protein response via aberrant activation of 4E-binding protein 1 by versipelostatin. | Cancer science 20090201 |
| mTOR regulates vascular smooth muscle cell differentiation from human bone marrow-derived mesenchymal progenitors. | Arteriosclerosis, thrombosis, and vascular biology 20090201 |
| Blocking eukaryotic initiation factor 4F complex formation does not inhibit the mTORC1-dependent activation of protein synthesis in cardiomyocytes. | American journal of physiology. Heart and circulatory physiology 20090201 |
| Impact of a prolonged delivery inflation time for optimal drug-eluting stent expansion. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090201 |
| Targeting heat-shock protein 90 improves efficacy of rapamycin in a model of hepatocellular carcinoma in mice. | Hepatology (Baltimore, Md.) 20090201 |
| LPS-induced autophagy is mediated by oxidative signaling in cardiomyocytes and is associated with cytoprotection. | American journal of physiology. Heart and circulatory physiology 20090201 |
| Belatacept as maintenance immunosuppression for postrenal transplant de novo drug-induced thrombotic microangiopathy. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090201 |
| Amino acid limitation regulates the expression of genes involved in several specific biological processes through GCN2-dependent and GCN2-independent pathways. | The FEBS journal 20090201 |
| Pretreatment with insulin before ischaemia reduces infarct size in Langendorff-perfused rat hearts. | Acta physiologica (Oxford, England) 20090201 |
| Metallothionein: a new soldier in the fight against chronic renal hypoxia? | Kidney international 20090201 |
| Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways. | International journal of oncology 20090201 |
| Laminar and compartmental regulation of dendritic growth in mature cortex. | Nature neuroscience 20090201 |
| Inflation time and drug-eluting stent: the longer, the better.. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090201 |
| Cost-effectiveness of drug-eluting stents including the economic impact of late stent thrombosis. | The American journal of cardiology 20090201 |
| Comparison of the sirolimus-eluting versus paclitaxel-eluting coronary stent in patients with diabetes mellitus: the diabetes and drug-eluting stent (DiabeDES) randomized angiography trial. | The American journal of cardiology 20090201 |
| In early-stage diabetic retinopathy, risk of cardiac events after implantation of sirolimus-eluting stent is higher than after coronary artery bypass surgery. | Journal of cardiology 20090201 |
| Inhibition of class I phosphoinositide 3-kinase activity impairs proliferation and triggers apoptosis in acute promyelocytic leukemia without affecting atra-induced differentiation. | Cancer research 20090201 |
| The protein kinase Tor1 regulates adhesin gene expression in Candida albicans. | PLoS pathogens 20090201 |
| Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2. | PLoS biology 20090201 |
| Common variable immunodeficiency with regulatory T-cell deficiency treated with rapamycin. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20090201 |
| Activation of the AKT and mammalian target of rapamycin pathways and the inhibitory effects of rapamycin on those pathways in canine malignant melanoma cell lines. | American journal of veterinary research 20090201 |
| Multiple spontaneous coronary artery dissection associated with a left main coronary artery lesion treated by stenting. Late multiple stent fractures detected by multislice CT. | Revista espanola de cardiologia 20090201 |
| FKBP12 depletion leads to loss of sarcoplasmic reticulum Ca(2+) stores in rat vas deferens. | Journal of pharmacological sciences 20090201 |
| mTOR-blocking agents in advanced renal cancer: an emerging therapeutic option. | Expert opinion on investigational drugs 20090201 |
| Interaction with phosphoinositides confers adaptation onto the TRPV1 pain receptor. | PLoS biology 20090201 |
| Tacrolimus pharmacokinetic drug interactions: effect of prednisone, mycophenolic acid or sirolimus. | Fundamental & clinical pharmacology 20090201 |
| Optical coherence tomography to diagnose under-expansion of a drug-eluting stent. | JACC. Cardiovascular imaging 20090201 |
| Clinical and angiographic outcomes with sirolimus-eluting stents in total coronary occlusions: the ACROSS/TOSCA-4 (Approaches to Chronic Occlusions With Sirolimus-Eluting Stents/Total Occlusion Study of Coronary Arteries-4) trial. | JACC. Cardiovascular interventions 20090201 |
| [The effect of rapamycin liposome gutta inhibiting rat corneal neovascularization]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20090201 |
| Randomized comparison of coronary bifurcation stenting with the crush versus the culotte technique using sirolimus eluting stents: the Nordic stent technique study. | Circulation. Cardiovascular interventions 20090201 |
| Novel role of the CXC chemokine receptor 3 in inflammatory response to arterial injury: involvement of mTORC1. | Circulation research 20090130 |
| The Rheb-mTOR pathway is upregulated in reactive astrocytes of the injured spinal cord. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090128 |
| Safety and pharmacokinetics of paclitaxel and the oral mTOR inhibitor everolimus in advanced solid tumours. | British journal of cancer 20090127 |
| Temozolomide- and fotemustine-induced apoptosis in human malignant melanoma cells: response related to MGMT, MMR, DSBs, and p53. | British journal of cancer 20090127 |
| What does the CONVERT trial really tell us about conversion from calcineurin inhibitors to sirolimus? | Transplantation 20090127 |
| Conversion from calcineurin inhibitors to sirolimus maintenance therapy in renal allograft recipients: 24-month efficacy and safety results from the CONVERT trial. | Transplantation 20090127 |
| A systematic approach to minimizing wound problems for de novo sirolimus-treated kidney transplant recipients. | Transplantation 20090127 |
| LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition. | British journal of cancer 20090127 |
| One year clinical and six month angiographic results of drug eluting stents for ST elevation acute myocardial infarction: 'real world' comparison between sirolimus- and paclitaxel-eluting stents. | International journal of cardiology 20090124 |
| Rapamycin-induced Gln3 dephosphorylation is insufficient for nuclear localization: Sit4 and PP2A phosphatases are regulated and function differently. | The Journal of biological chemistry 20090123 |
| [SORT OUT II--a randomized study of drug-eluting coronary stents--secondary publication]. | Ugeskrift for laeger 20090119 |
| Three-year survival following multivessel percutaneous coronary intervention with bare-metal or drug-eluting stents in unselected patients. | The American journal of cardiology 20090115 |
| Inhibition of mTOR radiosensitizes soft tissue sarcoma and tumor vasculature. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090115 |
| Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20090110 |
| Clinical characteristics of stent fracture after sirolimus-eluting stent implantation. | International journal of cardiology 20090109 |
| Biomedicine. A new view on--and hope for--an old disease. | Science (New York, N.Y.) 20090109 |
| Biomedicine. A discriminating killer. | Science (New York, N.Y.) 20090109 |
| New uracil dimers showing erythroid differentiation inducing activities. | Journal of medicinal chemistry 20090108 |
| Glycemic control in patients with insulinoma treated with everolimus. | The New England journal of medicine 20090108 |
| Randomized study of the crush technique versus provisional side-branch stenting in true coronary bifurcations: the CACTUS (Coronary Bifurcations: Application of the Crushing Technique Using Sirolimus-Eluting Stents) Study. | Circulation 20090106 |
| SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression. | FEBS letters 20090105 |
| Rapamycin instead of mycophenolate mofetil or azathioprine in treatment of post-renal transplantation urothelial carcinoma. | Chinese medical journal 20090105 |
| Clinical outcomes of serolimus-eluting stents versus bare metal stents in ST-segment elevation myocardial infarction patients: a meta-analysis. | Chinese medical journal 20090105 |
| [Current concepts and treatment advances in systemic mastocytosis]. | La Revue de medecine interne 20090101 |
| Rapamycin and mTOR-independent autophagy inducers ameliorate toxicity of polyglutamine-expanded huntingtin and related proteinopathies. | Cell death and differentiation 20090101 |
| Moderate-severe renal insufficiency is a risk factor for sirolimus-eluting stent thrombosis. The RIFT study. | Cardiology 20090101 |
| Multigene targeting of signal transduction pathways for the treatment of breast and prostate tumors: comparison between combination therapies employing bispecific oligonucleotides with either Rapamycin or Paclitaxel. | Medical oncology (Northwood, London, England) 20090101 |
| Minimization protocols in pancreas transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20090101 |
| Immunosuppression without calcineurin inhibition: optimization of renal function in expanded criteria donor renal transplantation. | Clinical transplantation 20090101 |
| Metabolic control of T cell activation and death in SLE. | Autoimmunity reviews 20090101 |
| Steroid withdrawal five days after renal transplantation allows for the prevention of wound-healing complications associated with sirolimus therapy. | Clinical transplantation 20090101 |
| Influence of HLA disparity, immunosuppressive regimen used, and type of kidney allograft on production of anti-HLA class-I antibodies after transplant and occurrence of rejection. | Immunopharmacology and immunotoxicology 20090101 |
| Activation of HIF-1alpha in exponentially growing cells via hypoxic stimulation is independent of the Akt/mTOR pathway. | Journal of cellular physiology 20090101 |
| Different profile of gene expression of cytokines in peripheral blood mononuclear cells of transplant recipients treated with m-TOR inhibitor and calcineurin inhibitor. | Transplant immunology 20090101 |
| The characteristics and in vivo suppression of neointimal formation with sirolimus-eluting polymeric stents. | Biomaterials 20090101 |
| The tuberous sclerosis proteins regulate formation of the primary cilium via a rapamycin-insensitive and polycystin 1-independent pathway. | Human molecular genetics 20090101 |
| Rapamycin attenuates the severity of murine adriamycin nephropathy. | American journal of nephrology 20090101 |
| Calcineurin-inhibitor minimization protocols in heart transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20090101 |
| Portal venous donor-specific transfusion in conjunction with sirolimus prolongs renal allograft survival in nonhuman primates. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20090101 |
| Mechanisms behind the synergistic effect of sirolimus and imatinib in preventing restenosis after intimal injury. | Journal of vascular research 20090101 |
| Regulation of placental amino acid transporter activity by mammalian target of rapamycin. | American journal of physiology. Cell physiology 20090101 |
| Treatment of refractory oral erosive lichen planus with topical rapamycin: 7 cases. | Dermatology (Basel, Switzerland) 20090101 |
| Significant association of coronary stent fracture with in-stent restenosis in sirolimus-eluting stents. | Coronary artery disease 20090101 |
| Limited utility of rapamycin in severe, refractory Wegener's granulomatosis. | The Journal of rheumatology 20090101 |
| Impact of direct sirolimus-eluting stent implantation on the early systemic inflammatory response compared with complementary stent implantation. | Coronary artery disease 20090101 |
| Use of rapamycin in the induction of tolerogenic dendritic cells. | Handbook of experimental pharmacology 20090101 |
| Inhibition of human immunodeficiency virus (HIV-1) infection in human peripheral blood leucocytes-SCID reconstituted mice by rapamycin. | Clinical and experimental immunology 20090101 |
| Three-year clinical outcome after primary stenting of totally occluded native coronary arteries: a randomized comparison of bare-metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions (Primary Stenting of Totally Occluded Native Coronary Arteries [PRISON] II study). | American heart journal 20090101 |
| Multicenter international registry of unprotected left main coronary artery percutaneous coronary intervention with drug-eluting stents in patients with myocardial infarction. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101 |
| Percutaneous revascularization of the 'unprotected' left main during acute myocardial infarction: 'Dare to struggle! Dare to win!'. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101 |
| Analysis of left main coronary artery bifurcation lesions treated with biolimus-eluting DEVAX AXXESS plus nitinol self-expanding stent: intravascular ultrasound results of the AXXENT trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101 |
| Treating the left main bifurcation lesion: the 'three stent solution'. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101 |
| Multiple stent fractures at the site of coronary artery bypass insertion. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101 |
| Coronary stent fracture: the hidden truth of a problem more common than stent thrombosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101 |
| Assessment with optical coherence tomography of a new strategy for bifurcational lesion treatment: the Tryton Side-Branch Stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101 |
| Step-by-step StentBoost-guided small vessel stenting using the self-expandable Sparrow stent-in-wire. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20090101 |
| Urine metabolites reflect time-dependent effects of cyclosporine and sirolimus on rat kidney function. | Chemical research in toxicology 20090101 |
| Sirolimus treatment for recurrent lymphangioleiomyomatosis after lung transplantation. | The Annals of thoracic surgery 20090101 |
| Characterization of the effects and functions of sumoylation through rapamycin-mediated heterodimerization. | Methods in molecular biology (Clifton, N.J.) 20090101 |
| San Antonio Breast Cancer Symposium. | The Lancet. Oncology 20090101 |
| Distinct roles for mammalian target of rapamycin complexes in the fibroblast response to transforming growth factor-beta. | Cancer research 20090101 |
| Therapeutic strategy targeting the mTOR-HIF-1alpha-VEGF pathway in ovarian clear cell adenocarcinoma. | Pathology international 20090101 |
| Photodynamic therapy targets the mTOR signaling network in vitro and in vivo. | Molecular pharmaceutics 20090101 |
| [Effect of Rapamycin and Cyclosporin A on the expression of TLR5 and Foxp3 in allorejection]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20090101 |
| Effect of sirolimus on urinary bladder cancer T24 cell line. | Journal of experimental & clinical cancer research : CR 20090101 |
| Sera from patients with diabetes do not alter the effect of mammalian target of rapamycin inhibition on smooth muscle cell proliferation. | Journal of cardiovascular pharmacology 20090101 |
| Everolimus-associated pneumonitis in 3 heart transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20090101 |
| Graft-versus-host disease prophylaxis with everolimus and tacrolimus is associated with a high incidence of sinusoidal obstruction syndrome and microangiopathy: results of the EVTAC trial. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20090101 |
| Rapamycin for chemoprevention of upper aerodigestive tract cancers. | Cancer prevention research (Philadelphia, Pa.) 20090101 |
| Targeting mammalian target of rapamycin by rapamycin prevents tumor progression in an oral-specific chemical carcinogenesis model. | Cancer prevention research (Philadelphia, Pa.) 20090101 |
| Regulation of D-cyclin translation inhibition in myeloma cells treated with mammalian target of rapamycin inhibitors: rationale for combined treatment with extracellular signal-regulated kinase inhibitors and rapamycin. | Molecular cancer therapeutics 20090101 |
| Bone growth during rapamycin therapy in young rats. | BMC pediatrics 20090101 |
| mTOR in growth and protection of hypertrophying myocardium. | Cardiovascular & hematological agents in medicinal chemistry 20090101 |
| Recent patents and patent applications relating to mTOR pathway. | Recent patents on DNA & gene sequences 20090101 |
| Inhibition of autophagy causes tau proteolysis by activating calpain in rat brain. | Journal of Alzheimer's disease : JAD 20090101 |
| Conditional nuclear import and export of yeast proteins using a chemical inducer of dimerization. | Cell biochemistry and biophysics 20090101 |
| The pharmacodynamic effect of sirolimus: individual variation of cytokine mRNA expression profiles in human whole blood samples. | Immunobiology 20090101 |
| Comparison of bare metal stent with pioglitazone versus sirolimus-eluting stent for percutaneous coronary intervention in patients with Type 2 diabetes mellitus. | Cardiovascular revascularization medicine : including molecular interventions 20090101 |
| Extremely late drug-eluting stent thrombosis: 2037 days after deployment. | Cardiovascular revascularization medicine : including molecular interventions 20090101 |
| [Assessment of the course of ischemic heart disease after placement of stents with drug covering and uncovered metal stents: data of 3 years follow-up]. | Kardiologiia 20090101 |
| Temsirolimus in patients with advanced renal cell carcinoma: an overview. | Advances in therapy 20090101 |
| Metastatic renal cell cancer treatments: an indirect comparison meta-analysis. | BMC cancer 20090101 |
| [Interdisciplinary recommendations for the treatment of metastatic renal cell carcinoma]. | Aktuelle Urologie 20090101 |
| Sirolimus-based rescue therapy after rejection in liver transplantation. | Clinical transplantation 20090101 |
| Cyclosporin A, but not everolimus, inhibits DNA repair in human fibroblasts and lymphoblasts. | International journal of clinical pharmacology and therapeutics 20090101 |
| Total synthesis of rapamycin. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090101 |
| Conversion to sirolimus with calcineurin inhibitor elimination vs. dose minimization and renal outcome in heart and lung transplant recipients. | Clinical transplantation 20090101 |
| [Topics in mTOR pathway and its inhibitors]. | Bulletin du cancer 20090101 |
| Temsirolimus-induced glomerulopathy. | Oncology 20090101 |
| Phase I study combining treatment with temsirolimus and sunitinib malate in patients with advanced renal cell carcinoma. | Clinical genitourinary cancer 20090101 |
| Chest pain without significant coronary stenosis after implantation of sirolimus-eluting stents. | Internal medicine (Tokyo, Japan) 20090101 |
| Effect of temsirolimus versus interferon-alpha on outcome of patients with advanced renal cell carcinoma of different tumor histologies. | Medical oncology (Northwood, London, England) 20090101 |
| Depletion of kinesin 5B affects lysosomal distribution and stability and induces peri-nuclear accumulation of autophagosomes in cancer cells. | PloS one 20090101 |
| No in vivo infection of triple immunosuppressed non-human primates after inoculation with high titers of porcine endogenous retroviruses. | Xenotransplantation 20090101 |
| Survival benefit in heart transplant recipients who have coronary artery disease confirmed using angiography and are receiving sirolimus. | Transplantation proceedings 20090101 |
| Rapamycin induces autophagy in islets: relevance in islet transplantation. | Transplantation proceedings 20090101 |
| Effects of systemic immunosuppression on islet engraftment and function into a subcutaneous biocompatible device. | Transplantation proceedings 20090101 |
| Effect of low-dose rapamycin on tumor growth in two human hepatocellular cancer cell lines. | Transplantation proceedings 20090101 |
| Effect of liver regeneration on the pharmacokinetics of immunosuppressive drugs. | Transplantation proceedings 20090101 |
| Rapamycin promotes the enrichment of CD4(+)CD25(hi)FoxP3(+) T regulatory cells from naïve CD4(+) T cells of baboon that suppress antiporcine xenogenic response in vitro. | Transplantation proceedings 20090101 |
| Sirolimus for rescue of steroid and anti-thymocyte globulin-resistant recurrent acute rejection after liver transplantation: report of one case. | Transplantation proceedings 20090101 |
| Late conversion to everolimus complicated with necrotizing glomerulonephritis in a renal allograft recipient: case report. | Transplantation proceedings 20090101 |
| Activated mammalian target of rapamycin is associated with T regulatory cell insufficiency in nasal polyps. | Respiratory research 20090101 |
| [A case of Kaposi's sarcoma in the rapamycin era]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20090101 |
| Low coronary flow velocity and shear stress predict restenosis after sirolimus-eluting stent implantation. | Scandinavian cardiovascular journal : SCJ 20090101 |
| Everolimus in liver and lung transplantation. | Drugs of today (Barcelona, Spain : 1998) 20090101 |
| The gender paradox. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101 |
| Observational studies of drug-eluting stents--some are more equal than others. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101 |
| Assessment of the absorption process following bioabsorbable everolimus-eluting stent implantation: temporal changes in strain values and tissue composition using intravascular ultrasound radiofrequency data analysis. A substudy of the ABSORB clinical trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101 |
| Long-term follow-up of percutaneous coronary intervention of unprotected left main lesions with drug eluting stents: predictors of clinical outcome. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101 |
| The relative safety and efficacy of bare-metal and drug-eluting stents in low and high-risk patient subsets. An epidemiological analysis of three sequential cohorts of consecutive all comers (n = 6129). | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101 |
| Effect of gender differences on early and mid-term clinical outcome after percutaneous or surgical coronary revascularisation in patients with multivessel coronary artery disease: insights from ARTS I and ARTS II. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101 |
| In vivo evaluation of a biolimus eluting nickel titanium self expanding stent with overlapping balloon expandable drug eluting and bare metal stents in a porcine coronary model. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20090101 |
| Metabolic profiles in urine reflect nephrotoxicity of sirolimus and cyclosporine following rat kidney transplantation. | Nephron. Experimental nephrology 20090101 |
| Conditional protein stabilization via the small molecules Shld-1 and rapamycin increases the signal-to-noise ratio with tet-inducible gene expression. | BioTechniques 20090101 |
| Glucose amplifies fatty acid-induced endoplasmic reticulum stress in pancreatic beta-cells via activation of mTORC1. | PloS one 20090101 |
| A rapid HPLC-MS/MS method for the simultaneous quantification of cyclosporine A, tacrolimus, sirolimus and everolimus in human blood samples. | Nature protocols 20090101 |
| A central role for Foxp3+ regulatory T cells in K-Ras-driven lung tumorigenesis. | PloS one 20090101 |
| Testing intravitreal toxicity of rapamycin in rabbit eyes. | Arquivos brasileiros de oftalmologia 20090101 |
| Rapamycin weekly maintenance dosing and the potential efficacy of combination sorafenib plus rapamycin but not atorvastatin or doxycycline in tuberous sclerosis preclinical models. | BMC pharmacology 20090101 |
| Ligand-regulated peptide aptamers. | Methods in molecular biology (Clifton, N.J.) 20090101 |
| Systemic chemoprevention. | Cancer treatment and research 20090101 |
| Larger dosage required for everolimus than sirolimus to maintain same blood concentration in two pancreatic islet transplant patients with tacrolimus. | Drug metabolism and pharmacokinetics 20090101 |
| Fibrocyte CXCR4 regulation as a therapeutic target in pulmonary fibrosis. | The international journal of biochemistry & cell biology 20090101 |
| [Targeting of the AKT-mTOR pathway in head and neck and lung cancer]. | Bulletin du cancer 20090101 |
| Diabetes mellitus: a prothrombotic state implications for outcomes after coronary revascularization. | Vascular health and risk management 20090101 |
| Interferon-alpha-induced mTOR activation is an anti-hepatitis C virus signal via the phosphatidylinositol 3-kinase-Akt-independent pathway. | Journal of gastroenterology 20090101 |
| Rapamycin inhibits growth of cholangiocarcinoma cells. | Hepato-gastroenterology 20090101 |
| A kinase-dead knock-in mutation in mTOR leads to early embryonic lethality and is dispensable for the immune system in heterozygous mice. | BMC immunology 20090101 |
| Sirolimus-eluting stents or vascular brachytherapy for in-stent restenosis after 3-year follow-up of the SISR (Sirolimus-Eluting Stent Versus Vascular Brachytherapy for In-Stent Restenosis) trial: a call for caution? | JACC. Cardiovascular interventions 20090101 |
| Rapamycin suppresses seizures and neuronal hypertrophy in a mouse model of cortical dysplasia. | Disease models & mechanisms 20090101 |
| Combining the receptor tyrosine kinase inhibitor AEE788 and the mammalian target of rapamycin (mTOR) inhibitor RAD001 strongly inhibits adhesion and growth of renal cell carcinoma cells. | BMC cancer 20090101 |
| Relationship between renal resistance index and renal function in liver transplant recipients after cessation of calcineurin inhibitor. | Clinical transplantation 20090101 |
| The influence of commonly used immunosuppressive drugs on the small bowel functions - a comparative experimental study. | Annals of transplantation 20090101 |
| Current status and challenges associated with targeting mTOR for cancer therapy. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20090101 |
| Management of metabolic cytochrome P450 3A4 drug-drug interaction between everolimus and azole antifungals in a renal transplant patient. | Clinical drug investigation 20090101 |
| Formalin-induced behavioural hypersensitivity and neuronal hyperexcitability are mediated by rapid protein synthesis at the spinal level. | Molecular pain 20090101 |
| Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets. | Cell transplantation 20090101 |
| Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis. | Molecular cancer 20090101 |
| [Long-term results of coronary endovascular revascularisation with sirolimus-eluting stents in patients with ischemic heart disease comorbid with type-2 diabetes mellitus: data from 18-month prospective study]. | Terapevticheskii arkhiv 20090101 |
| Differential responses of human regulatory T cells (Treg) and effector T cells to rapamycin. | PloS one 20090101 |
| New approach for local delivery of rapamycin by bioadhesive PLGA-carbopol nanoparticles. | Drug delivery 20090101 |
| Noninvasive evaluation of coronary endothelial function following sirolimus-eluting stent implantation by using positron emission tomography. | Cardiology 20090101 |
| There is a choice for immunosuppressive drug nephrotoxicity: Is it time to change? | Journal of nephrology 20090101 |
| Cost effectiveness of sirolimus-eluting stents compared with bare metal stents in acute myocardial infarction: insights from the TYPHOON trial. | Applied health economics and health policy 20090101 |
| Methods for analysis of brain tumor stem cell and neural stem cell self-renewal. | Methods in molecular biology (Clifton, N.J.) 20090101 |
| Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells. | Molecular pharmaceutics 20090101 |
| Human protein phosphatase PP6 regulatory subunits provide Sit4-dependent and rapamycin-sensitive sap function in Saccharomyces cerevisiae. | PloS one 20090101 |
| [Economic evaluation and budget impact analysis of the Endeavor drug-eluting stent in Spain]. | Gaceta sanitaria 20090101 |
| Optimizing immunosuppression with sirolimus in the first year posttransplantation: experience in the United States. | Transplantation proceedings 20090101 |
| Where did we leave off in 2008? Conclusions from the 8th International Symposium. | Transplantation proceedings 20090101 |
| Reducing the risk of left ventricular hypertrophy in kidney transplant recipients: the potential role of mammalian target of rapamycin. | Transplantation proceedings 20090101 |
| New approaches to de novo immunosuppression and steroid elimination. | Transplantation proceedings 20090101 |
| De novo immunosuppression with mammalian target of rapamycin inhibitors and posttransplantation malignancy in focus. | Transplantation proceedings 20090101 |
| [Association between late incomplete stent apposition after sirolimus eluting stent implantation and clinical outcomes in patients with acute coronary syndrome]. | Zhonghua xin xue guan bing za zhi 20090101 |
| Timing of sirolimus conversion influences recovery of renal function in liver transplant recipients. | Clinical transplantation 20090101 |
| Combination of everolimus and tacrolimus in kidney transplant patients with intolerance to mycophenolate mofetil/mycophenolic acid. | Transplantation proceedings 20090101 |
| De novo kidney transplant recipients need higher doses of Advagraf compared with Prograf to get therapeutic levels. | Transplantation proceedings 20090101 |
| Conversion to everolimus in kidney transplant recipients with decreased renal function. | Transplantation proceedings 20090101 |
| Evaluation of the efficacy and safety of conversion to sirolimus in 85 renal transplant recipients. | Transplantation proceedings 20090101 |
| Sirolimus and everolimus induced pneumonitis in adult renal allograft recipients: experience in a center. | Transplantation proceedings 20090101 |
| Indications and management of everolimus after liver transplantation. | Transplantation proceedings 20090101 |
| Efficacy, tolerance, and safety of mammalian target of rapamycin inhibitors as rescue immunosuppressants in liver transplantation. | Transplantation proceedings 20090101 |
| Everolimus represents an advance in immunosuppression for patients who have developed cancer after renal transplantation. | Transplantation proceedings 20090101 |
| Switching to sirolimus in renal transplant recipients with hepatitis C virus: a safe option. | Transplantation proceedings 20090101 |
| Similar lipid profile but improved long-term outcomes with sirolimus after cyclosporine withdrawal compared to sirolimus with continuous cyclosporine. | Transplantation proceedings 20090101 |
| Complete switch to everolimus in long-term kidney transplants: evolution of the renal function. | Transplantation proceedings 20090101 |
| Clinical implications of proteinuria in renal transplant recipients switching to rapamycin for chronic allograft dysfunction. | Transplantation proceedings 20090101 |
| Monotherapy rapamycin in renal transplant recipients with lymphoma successfully treated with rituximab. | Transplantation proceedings 20090101 |
| FTY720 and everolimus in de novo renal transplant patients at risk for delayed graft function: results of an exploratory one-yr multicenter study. | Clinical transplantation 20090101 |
| Chronic allograft nephropathy--a clinical syndrome: early detection and the potential role of proliferation signal inhibitors. | Clinical transplantation 20090101 |
| Stent thrombosis four and a half years after implantation of a sirolimus-eluting stent. | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20090101 |
| Post-transplantation malignancy: a cell autonomous mechanism with implications for therapy. | Transactions of the American Clinical and Climatological Association 20090101 |
| Interstitial pneumonitis in the transplant patient: consider sirolimus-associated pulmonary toxicity. | The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20090101 |
| The rapamycin-regulated gene expression signature determines prognosis for breast cancer. | Molecular cancer 20090101 |
| Comparative analysis of neointimal coverage with paclitaxel and zotarolimus drug-eluting stents, using optical coherence tomography 6 months after implantation. | Archives of cardiovascular diseases 20090101 |
| New therapeutic approaches in the management of metastatic renal cell carcinoma. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20090101 |
| Can proliferation signal inhibitor-induced Tregs really reflect transplantation tolerance in clinical solid organ transplantation? | International reviews of immunology 20090101 |
| Effects of everolimus on cytokines, oxidative stress, and renal histology in ischemia-reperfusion injury of the kidney. | Renal failure 20090101 |
| Multiple coronary artery aneurysm formation one year and four years after sirolimus-eluting coronary stent implantation. | Cardiovascular revascularization medicine : including molecular interventions 20090101 |
| Rapamycin response in tumorigenic and non-tumorigenic hepatic cell lines. | PloS one 20090101 |
| Limited sampling models and Bayesian estimation for mycophenolic acid area under the curve prediction in stable renal transplant patients co-medicated with ciclosporin or sirolimus. | Clinical pharmacokinetics 20090101 |
| [Pneumonitis caused by sirolimus: improvement after switching to everolimus]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101 |
| [The influence of coronary stenting with rapamycin-eluting stents on the number of circulating CD4+CD25high+regulatory T-cells]. | Terapevticheskii arkhiv 20090101 |
| Rapid modification of proteins using a rapamycin-inducible tobacco etch virus protease system. | PloS one 20090101 |
| Malignant epithelioid angiomyolipoma in the kidney and liver of a patient with pulmonary lymphangioleiomyomatosis: lack of response to sirolimus. | Internal medicine (Tokyo, Japan) 20090101 |
| Development and characterization of liposomal formulations for rapamycin delivery and investigation of their antiproliferative effect on MCF7 cells. | Journal of liposome research 20090101 |
| Induction of granzyme B expression in T-cell receptor/CD28-stimulated human regulatory T cells is suppressed by inhibitors of the PI3K-mTOR pathway. | BMC immunology 20090101 |
| Conversion from cyclosporin A to sirolimus retards the progression of chronic allograft nephropathy in the long term in a rat kidney transplantation model. | The Journal of international medical research 20090101 |
| mTOR regulation and therapeutic rejuvenation of aging hematopoietic stem cells. | Science signaling 20090101 |
| [Acute renal failure in a patient with renal carcinoma treated with temsirolimus]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20090101 |
| Adherence must always be considered: is everolimus really ineffective as a treatment for atopic dermatitis? | The Journal of dermatological treatment 20090101 |
| Severe atopic dermatitis treated with everolimus. | The Journal of dermatological treatment 20090101 |
| Repeated plaque prolapse after sirolimus-eluting stent implantation in the treatment of chronic total occlusion lesion. | Acute cardiac care 20090101 |
| Inhibition of mTOR Activates the MAPK Pathway in Glioblastoma Multiforme. | Cancer genomics & proteomics 20090101 |
| Controversies in breast cancer: the mammalian target of rapamycin as a target for breast cancer therapy. | Breast cancer research : BCR 20090101 |
| Update on the everolimus-eluting coronary stent system: results and implications from the SPIRIT clinical trial program. | Vascular health and risk management 20090101 |
| Combined effect of rapamycin and cisplatin on survival of Hep-2 cells in vitro. | Oncology research 20090101 |
| Fracture of zotarolimus-eluting stent after implantation. | Texas Heart Institute journal 20090101 |
| Mycophenolate mofetil versus Rapamycin in Han: SPRD rats with Polycystic Kidney Disease. | Biological research 20090101 |
| Extension of chronological life span by reduced TOR signaling requires down-regulation of Sch9p and involves increased mitochondrial OXPHOS complex density. | Aging 20090101 |
| Rapamycin does not adversely affect intrahepatic islet engraftment in mice and improves early islet engraftment in humans. | Islets 20090101 |
| Islet transplantation with alemtuzumab induction and calcineurin-free maintenance immunosuppression results in improved short- and long-term outcomes. | Transplantation 20081227 |
| Safety and efficacy of statin therapy in patients switched from cyclosporine a to sirolimus after cardiac transplantation. | Transplantation 20081227 |
| Rapamycin reverses TLR4 signaling-triggered tumor apoptosis resistance by disrupting Akt-mediated Bcl-xL upregulation. | International immunopharmacology 20081220 |
| Acute coronary syndrome is an independent risk factor for late incomplete stent apposition after sirolimus-eluting stent implantation. | Chinese medical journal 20081220 |
| Treatment of diffuse in-stent restenosis with drug-eluting stents vs. intracoronary beta-radiation therapy: INDEED Study. | International journal of cardiology 20081217 |
| Endothelialization and late stent thrombosis in diabetics. | Journal of the American College of Cardiology 20081216 |
| mTOR complex 2 (mTORC2) controls hydrophobic motif phosphorylation and activation of serum- and glucocorticoid-induced protein kinase 1 (SGK1). | The Biochemical journal 20081215 |
| Mass balance in rapamycin autoxidation. | Journal of pharmaceutical and biomedical analysis 20081215 |
| Overview of the 2007 Food and Drug Administration Circulatory System Devices Panel meeting on the Xience V Everolimus-Eluting Coronary Stent. | The American journal of cardiology 20081215 |
| Inhibition of Mammalian target of rapamycin by rapamycin causes the regression of carcinogen-induced skin tumor lesions. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081215 |
| Deconstructing feedback-signaling networks to improve anticancer therapy with mTORC1 inhibitors. | Cell cycle (Georgetown, Tex.) 20081215 |
| Differential dependence of hypoxia-inducible factors 1 alpha and 2 alpha on mTORC1 and mTORC2. | The Journal of biological chemistry 20081212 |
| Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis after allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081210 |
| Multivessel coronary revascularization in patients with and without diabetes mellitus: 3-year follow-up of the ARTS-II (Arterial Revascularization Therapies Study-Part II) trial. | Journal of the American College of Cardiology 20081209 |
| Akt determines replicative senescence and oxidative or oncogenic premature senescence and sensitizes cells to oxidative apoptosis. | Cancer cell 20081209 |
| Recovery of tacrolimus-associated brachial neuritis after conversion to everolimus in a pediatric renal transplant recipient--case report and review of the literature. | Pediatric transplantation 20081201 |
| Involvement of the TGF-beta and mTOR/p70S6Kinase pathways in the transformation process induced by v-ErbA. | Leukemia research 20081201 |
| Induction of HIF-1alpha expression by intermittent hypoxia: involvement of NADPH oxidase, Ca2+ signaling, prolyl hydroxylases, and mTOR. | Journal of cellular physiology 20081201 |
| Low viral load post-transplant lymphoproliferative disease localized within the tongue. | Transplant infectious disease : an official journal of the Transplantation Society 20081201 |
| Sirolimus in unmanipulated haploidentical cell transplantation. | Bone marrow transplantation 20081201 |
| Rheb activates protein synthesis and growth in adult rat ventricular cardiomyocytes. | Journal of molecular and cellular cardiology 20081201 |
| Genome-wide expression analysis reveals TORC1-dependent and -independent functions of Sch9. | FEMS yeast research 20081201 |
| Protective role of autophagy in neonatal hypoxia-ischemia induced brain injury. | Neurobiology of disease 20081201 |
| Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation. | Blood 20081201 |
| Blockade of mTOR signaling potentiates the ability of histone deacetylase inhibitor to induce growth arrest and differentiation of acute myelogenous leukemia cells. | Leukemia 20081201 |
| Exploring the role of novel agents in the treatment of renal cell carcinoma. | Cancer treatment reviews 20081201 |
| ERK and p38 pathways regulate amino acid signalling. | Biochimica et biophysica acta 20081201 |
| Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells. | Carcinogenesis 20081201 |
| Ethylenecarbodiimide-coupled allogeneic antigen presenting cells induce human CD4+ regulatory T cells. | Clinical immunology (Orlando, Fla.) 20081201 |
| Randomized trial on routine vs. provisional T-stenting in the treatment of de novo coronary bifurcation lesions. | European heart journal 20081201 |
| The effect of sirolimus on prostate-specific antigen (PSA) levels in male renal transplant recipients without prostate cancer. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081201 |
| CD8+ T-Cell depletion and rapamycin synergize with combined coreceptor/stimulation blockade to induce robust limb allograft tolerance in mice. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081201 |
| ABT-869, a multi-targeted tyrosine kinase inhibitor, in combination with rapamycin is effective for subcutaneous hepatocellular carcinoma xenograft. | Journal of hepatology 20081201 |
| Laryngeal transplantation in the setting of cancer: a rat model. | The Laryngoscope 20081201 |
| Identification of the rapamycin-sensitive phosphorylation sites within the Ser/Thr-rich domain of the yeast Npr1 protein kinase. | Rapid communications in mass spectrometry : RCM 20081201 |
| Temsirolimus in patients with renal cancer on hemodialysis. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081201 |
| Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy. | Cancer biology & therapy 20081201 |
| Ocular toxicity and distribution of subconjunctival and intravitreal rapamycin in horses. | Journal of veterinary pharmacology and therapeutics 20081201 |
| Culotte stenting technique in coronary bifurcation disease: angiographic follow-up using dedicated quantitative coronary angiographic analysis and 12-month clinical outcomes. | European heart journal 20081201 |
| Deforolimus (AP23573) a novel mTOR inhibitor in clinical development. | Expert opinion on investigational drugs 20081201 |
| Regulation of adiponectin secretion by insulin and amino acids in 3T3-L1 adipocytes. | Metabolism: clinical and experimental 20081201 |
| The pharmacokinetics of Biolimus A9 after elution from the Nobori stent in patients with coronary artery disease: the NOBORI PK study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081201 |
| Inhibition of the alloimmune response through the generation of regulatory T cells by a MHC class II-derived peptide. | Journal of immunology (Baltimore, Md. : 1950) 20081201 |
| CD40-induced signaling in human endothelial cells results in mTORC2- and Akt-dependent expression of vascular endothelial growth factor in vitro and in vivo. | Journal of immunology (Baltimore, Md. : 1950) 20081201 |
| Insulin-like growth factor stimulation increases radiosensitivity of a pancreatic cancer cell line through endoplasmic reticulum stress under hypoxic conditions. | Cancer science 20081201 |
| LC3-I conversion to LC3-II does not necessarily result in complete autophagy. | International journal of molecular medicine 20081201 |
| Is there a preferable DES in diabetic patients? A critical appraisal of the evidence. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081201 |
| Sirolimus ameliorated post lung transplant chylothorax in lymphangioleiomyomatosis. | The Annals of thoracic surgery 20081201 |
| Treatment for genetic diseases. | Current opinion in pediatrics 20081201 |
| Incidence of bleeding and compliance on prolonged dual antiplatelet therapy (aspirin + thienopyridine) following drug-eluting stent implantation. | The American journal of cardiology 20081201 |
| Very late thrombosis of sirolimus-eluting stent due to late malapposition: serial observations with optical coherence tomography. | Journal of cardiology 20081201 |
| A whole-animal microplate assay for metabolic rate using zebrafish. | Journal of biomolecular screening 20081201 |
| Autophagy-induced tumor dormancy in ovarian cancer. | The Journal of clinical investigation 20081201 |
| The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells. | The Journal of clinical investigation 20081201 |
| Rapamycin shows anticancer activity in primary chronic lymphocytic leukemia cells in vitro, as single agent and in drug combination. | Leukemia & lymphoma 20081201 |
| Formalin can alter the intracellular localization of some transcription factors in Saccharomyces cerevisiae. | FEMS yeast research 20081201 |
| Endothelialization of sirolimus-eluting stents with slow and extended drug release in the porcine overstretch model. | The Journal of invasive cardiology 20081201 |
| Proliferation signal inhibitor-induced decrease of vascular endothelial cadherin expression and increase of endothelial permeability in vitro are prevented by an anti-oxidant. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081201 |
| Epstein-Barr virus, rapamycin, and host immune responses. | Current opinion in organ transplantation 20081201 |
| In vivo characterization of a polymeric nanoparticle platform with potential oral drug delivery capabilities. | Molecular cancer therapeutics 20081201 |
| Re: 'midterm results of a sirolimus-eluting stent implanted for recurrent carotid in-stent restenosis'. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20081201 |
| [Everolimus (RAD001) and solid tumours: a 2008 summary]. | Bulletin du cancer 20081201 |
| Therapeutic effect of Tripterygium wilfordii on proteinuria associated with sirolimus in renal transplant recipients. | Transplantation proceedings 20081201 |
| Sirolimus-based immunosuppression therapy in liver transplantation for patients with hepatocellular carcinoma exceeding the Milan criteria. | Transplantation proceedings 20081201 |
| Conversion to sirolimus in kidney-pancreas and pancreas transplantation. | Transplantation proceedings 20081201 |
| A combination of donor specific transfusion and rapamycin prolongs cardiac allograft survival in mice. | Transplantation proceedings 20081201 |
| Treatment of chronic allograft nephropathy at late stages using everolimus or FTY720 in combination with cyclosporine. | Transplantation proceedings 20081201 |
| Severe sirolimus-related inflammatory state anemia in an HIV+ liver transplant patient with calcineurin inhibitor renal insufficiency: a case report. | Transplantation proceedings 20081201 |
| Fifteen years of clinical studies and clinical practice in renal transplantation: reviewing outcomes with de novo use of sirolimus in combination with cyclosporine. | Transplantation proceedings 20081201 |
| Modern approaches to combining sirolimus with calcineurin inhibitors. | Transplantation proceedings 20081201 |
| Reviewing the evidence for de novo immunosuppression with sirolimus. | Transplantation proceedings 20081201 |
| Optimizing early de novo immunosuppression with sirolimus. | Transplantation proceedings 20081201 |
| The impact of mTOR inhibitors on the development of malignancy. | Transplantation proceedings 20081201 |
| Temsirolimus in renal cell carcinoma. | Transplantation proceedings 20081201 |
| Minimizing the risk of posttransplant malignancy. | Transplantation proceedings 20081201 |
| New approaches to de novo immunosuppression and steroid elimination. | Transplantation proceedings 20081201 |
| Stratifying risk and targeting immunosuppressive strategies. | Transplantation proceedings 20081201 |
| Treatment of saphenous vein graft lesions with paclitaxel- and sirolimus-eluting stents: comparison of short- and long-term clinical outcomes. | Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology 20081201 |
| Rapamycin inhibits growth factor-induced cell cycle regulation in pancreatic beta cells. | Journal of investigative medicine : the official publication of the American Federation for Clinical Research 20081201 |
| [Outcome of patients implanted with bioabsorbable polymer sirolimus-eluting stent (Excel) and the durable polymer sirolimus-eluting stent (Cypher)]. | Zhonghua xin xue guan bing za zhi 20081201 |
| Comparison of vasa vasorum after intravascular stent placement with sirolimis drug-eluting and bare metal stents. | Journal of medical imaging and radiation oncology 20081201 |
| Effects of rapamycin on intracellular cholesterol homeostasis of glomerular mesangial cell in the presence of interleukin-1 beta. | Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20081201 |
| [Expression of mammalian target of rapamycin and p70 S6 kinase in rabbit periodontal tissues remodeling during orthodontic tooth movement]. | Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20081201 |
| Temsirolimus: new drug. Metastatic kidney cancer: more assessment needed. | Prescrire international 20081201 |
| Common corruption of the mTOR signaling network in human tumors. | Oncogene 20081201 |
| Interference of drug-eluting stents with endothelium-dependent coronary vasomotion: evidence for device-specific responses. | Circulation. Cardiovascular interventions 20081201 |
| Inhibition of apoptosis through localized delivery of rapamycin-loaded nanoparticles prevented neointimal hyperplasia and reendothelialized injured artery. | Circulation. Cardiovascular interventions 20081201 |
| Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival. | Oncogene 20081127 |
| Sirolimus as primary immunosuppressant reduces left ventricular mass and improves diastolic function of the cardiac allograft. | Transplantation 20081127 |
| Comparison of sirolimus plus tacrolimus versus sirolimus plus cyclosporine in high-risk renal allograft recipients: results from an open-label, randomized trial. | Transplantation 20081115 |
| Susceptibility of human mesenchymal stem cells to tacrolimus, mycophenolic acid, and rapamycin. | Transplantation 20081115 |
| Effects of immunosuppressive drugs on purified human B cells: evidence supporting the use of MMF and rapamycin. | Transplantation 20081115 |
| Serial angiographic and intravascular ultrasound analysis of late stent strut fracture of sirolimus-eluting stents in native coronary arteries. | International journal of cardiology 20081112 |
| Fracture of a sirolimus-eluting stent with migration. | International journal of cardiology 20081112 |
| Thrombus causes fluctuations in arterial drug delivery from intravascular stents. | Journal of controlled release : official journal of the Controlled Release Society 20081112 |
| Late stent recoil of the bioabsorbable everolimus-eluting coronary stent and its relationship with plaque morphology. | Journal of the American College of Cardiology 20081111 |
| Long-term clinical benefit of sirolimus-eluting stents in patients with in-stent restenosis results of the RIBS-II (Restenosis Intra-stent: Balloon angioplasty vs. elective sirolimus-eluting Stenting) study. | Journal of the American College of Cardiology 20081111 |
| A mathematical model for predicting drug release from a biodurable drug-eluting stent coating. | Journal of biomedical materials research. Part A 20081101 |
| Tacrolimus withdrawal and conversion to sirolimus at three months post-pediatric renal transplantation. | Pediatric transplantation 20081101 |
| Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR. | Cerebral cortex (New York, N.Y. : 1991) 20081101 |
| Cyclin B synthesis and rapamycin-sensitive regulation of protein synthesis during starfish oocyte meiotic divisions. | Molecular reproduction and development 20081101 |
| [Primary chronic autoimmune neutropenia successfully treated with sirolimus]. | La Revue de medecine interne 20081101 |
| Reactive oxygen species in tumor necrosis factor-alpha-activated primary human keratinocytes: implications for psoriasis and inflammatory skin disease. | The Journal of investigative dermatology 20081101 |
| mTOR mediates survival signals in malignant mesothelioma grown as tumor fragment spheroids. | American journal of respiratory cell and molecular biology 20081101 |
| Conversion to sirolimus for chronic renal allograft dysfunction: risk factors for graft loss and severe side effects. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081101 |
| Restoration of renal function in zebrafish models of ciliopathies. | Pediatric nephrology (Berlin, Germany) 20081101 |
| Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism. | Amino acids 20081101 |
| Dentritic cell derived IL-18 production is inhibited by rapamycin and sanglifehrin A, but not cyclosporine A. | Transplant immunology 20081101 |
| Differential promotion of hematopoietic chimerism and inhibition of alloreactive T cell proliferation by combinations of anti-CD40Ligand, anti-LFA-1, everolimus, and deoxyspergualin. | Transplant immunology 20081101 |
| Rapamycin reverses NPM-ALK-induced glucocorticoid resistance in lymphoid tumor cells by inhibiting mTOR signaling pathway, enhancing G1 cell cycle arrest and apoptosis. | Leukemia 20081101 |
| [Molecular basis of targeted therapy in metastatic renal cancer]. | Der Pathologe 20081101 |
| Rapamycin does not improve insulin sensitivity despite elevated mammalian target of rapamycin complex 1 activity in muscles of ob/ob mice. | American journal of physiology. Regulatory, integrative and comparative physiology 20081101 |
| Comparison of four different immunosuppression protocols without long-term steroid therapy in kidney recipients monitored by surveillance biopsy: five-year outcomes. | Transplant immunology 20081101 |
| Sirolimus affects cardiomyocytes to reduce left ventricular mass in heart transplant recipients. | European heart journal 20081101 |
| Sirolimus-based, calcineurin-inhibitor sparing immunotherapy, long-term (6-year) results. | Transplant immunology 20081101 |
| Prolonged insulin independence after islet allotransplants in recipients with type 1 diabetes. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20081101 |
| Pharmacokinetic interaction between everolimus and antifungal triazoles in a liver transplant patient. | The Annals of pharmacotherapy 20081101 |
| Targeting the mammalian target of rapamycin in myxoid chondrosarcoma. | Anti-cancer drugs 20081101 |
| Neointimal hyperplasia after sirolimus-eluting and paclitaxel-eluting stent implantation in diabetic patients: the Randomized Diabetes and Drug-Eluting Stent (DiabeDES) Intravascular Ultrasound Trial. | European heart journal 20081101 |
| [Myocardial revascularization: the point in 2008]. | Presse medicale (Paris, France : 1983) 20081101 |
| Immediate and long-term results of treatment of complex lesions of the left anterior descending coronary artery involving a large diagonal branch with drug-eluting stents. | Journal of cardiovascular medicine (Hagerstown, Md.) 20081101 |
| Switch of immunosuppression from cyclosporine A to everolimus: impact on pulse wave velocity in stable de-novo renal allograft recipients. | Journal of hypertension 20081101 |
| Mechanism of action of rapalogues: the antiangiogenic hypothesis. | Expert opinion on investigational drugs 20081101 |
| Drug-eluting stents for the treatment of ostial coronary lesions: comparison of sirolimus-eluting stent with paclitaxel-eluting stent. | Coronary artery disease 20081101 |
| Minimization of immunosuppression: transplant immunology. | Transplant immunology 20081101 |
| Sirolimus treatment of left ventricular hypertrophy: who, and when? | European heart journal 20081101 |
| Comparison of sirolimus-eluting stent and paclitaxel-eluting stent for long-term cardiac adverse events in diabetic patients: the Korean Multicenter Angioplasty Team (KOMATE) Registry. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081101 |
| Clinical presentation of patients with late target lesion revascularization. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081101 |
| Growth stimulation leads to cellular senescence when the cell cycle is blocked. | Cell cycle (Georgetown, Tex.) 20081101 |
| A randomized comparison of sirolimus-eluting versus bare metal stents in the treatment of diabetic patients with native coronary artery lesions: the DECODE study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081101 |
| Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma post-lung transplantation with rapamycin treatment. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081101 |
| Gingival status of Brazilian renal transplant recipients under sirolimus-based regimens. | Journal of periodontology 20081101 |
| Intractable Prinzmetal's angina three months after implantation of sirolimus-eluting stent. | The Journal of invasive cardiology 20081101 |
| Systemic immunosuppressive therapy with oral Sirolimus after bare metal stent implantation: the missing alternative in the prevention of coronary restenosis after percutaneous coronary interventions. | Recent patents on cardiovascular drug discovery 20081101 |
| Systemic therapy for metastatic renal cell carcinoma. | The Urologic clinics of North America 20081101 |
| [Treatment of drug-eluting stent restenosis with another drug-eluting stent: do not fail the second time!]. | Revista espanola de cardiologia 20081101 |
| [Treatment of Paclitaxel-eluting stent restenosis with sirolimus-eluting stent implantation: angiographic and clinical outcomes]. | Revista espanola de cardiologia 20081101 |
| [67-year-old patient with speech disorder and dysphagia]. | Deutsche medizinische Wochenschrift (1946) 20081101 |
| Tolerance profile of the proliferation signal inhibitors everolimus and sirolimus in heart transplantation. | Transplantation proceedings 20081101 |
| Preliminary experience with conversion from calcineurin inhibitors to everolimus in cardiac transplantation maintenance therapy. | Transplantation proceedings 20081101 |
| Conversion to rapamycin in a renal transplant patient with von Hippel-Lindau disease: encouraging results-a case report. | Transplantation proceedings 20081101 |
| Use of everolimus in de novo renal recipients: initial experience in the Greek population. | Transplantation proceedings 20081101 |
| Metabolic changes following conversion from an anticalcineurin-based therapy to an everolimus-based one: a single-center experience. | Transplantation proceedings 20081101 |
| Adipose-specific knockout of raptor results in lean mice with enhanced mitochondrial respiration. | Cell metabolism 20081101 |
| [Oral ulcers in kidney allograft recipients treated with sirolimus]. | Annales de dermatologie et de venereologie 20081101 |
| Percutaneous coronary implantation of sirolimus-eluting stents in unselected patients and lesions: clinical results and multiple outcome predictors. | American heart journal 20081101 |
| Long-term coronary endothelial function after zotarolimus-eluting stent implantation. A 9 month comparison between zotarolimus-eluting and sirolimus-eluting stents. | International heart journal 20081101 |
| Four-year safety and efficacy of the unrestricted use of sirolimus- and paclitaxel-eluting stents in coronary artery bypass grafts. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20081101 |
| Very late thrombosis in acute myocardial infarction: drug-eluting versus uncoated stents. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20081101 |
| Long-term safety and efficacy are observed after implantation of Zotarolimus-Eluting stent in real-world clinical practice. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20081101 |
| [Benefit-risk ratio of coronary drug-eluting stents: 2nd part: evaluation in the diabetic population]. | Revue medicale de Liege 20081101 |
| The changing face of angiographic patterns of restenosis after drug-eluting stent placement: sirolimus versus paclitaxel-eluting stent. | International journal of cardiology 20081030 |
| Simultaneous subacute stent thrombosis of two sirolimus-eluting stents in a patient treated by ReoPro, thrombus aspiration and triple anti-platelet agents. | International journal of cardiology 20081030 |
| Rapamycin downregulates the inhibitory receptors ILT2, ILT3, ILT4 on human dendritic cells and yet induces T cell hyporesponsiveness independent of FoxP3 induction. | Immunology letters 20081030 |
| One year follow-up of steroid-free immunosuppression plus everolimus in isolated pancreas transplantation. | Transplantation 20081027 |
| mTORC1 inhibitors: is temsirolimus in renal cancer telling us how they really work? | British journal of cancer 20081021 |
| [Effects of constant magnetic fields on proliferation and migration of endothelial progenitor cells under rapamycin intervention: experiment with rats]. | Zhonghua yi xue za zhi 20081021 |
| [Sirolimus inhibits the expression of type I collagen and fibronectin in cultured renal cortical myofibroblasts]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20081018 |
| Metabolic stress induces the lysosomal degradation of neuropilin-1 but not neuropilin-2. | The Journal of biological chemistry 20081017 |
| Melatonin prevents ischemic brain injury through activation of the mTOR/p70S6 kinase signaling pathway. | Neuroscience letters 20081017 |
| The TSC-mTOR signaling pathway regulates the innate inflammatory response. | Immunity 20081017 |
| Dual inhibition of PI3Kalpha and mTOR as an alternative treatment for Kaposi's sarcoma. | Cancer research 20081015 |
| Shp2 negatively regulates growth in cardiomyocytes by controlling focal adhesion kinase/Src and mTOR pathways. | Circulation research 20081010 |
| Very late stent fracture associated with a sirolimus-eluting stent. | Heart, lung & circulation 20081001 |
| An investigation of adhesion in drug-eluting stent layers. | Journal of biomedical materials research. Part A 20081001 |
| Lack of antileukemic activity of rapamycin in elderly patients with acute myeloid leukemia evolving from a myelodysplastic syndrome. | Leukemia research 20081001 |
| Sirolimus reduces the incidence and progression of UVB-induced skin cancer in SKH mice even with co-administration of cyclosporine A. | The Journal of investigative dermatology 20081001 |
| Different renal toxicity profiles in the association of cyclosporine and tacrolimus with sirolimus in rats. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001 |
| Thrombin induces osteoprotegerin synthesis via phosphatidylinositol 3'-kinase/mammalian target of rapamycin pathway in human periodontal ligament cells. | Journal of periodontal research 20081001 |
| [Value of targeted therapy for prostate cancer]. | Der Urologe. Ausg. A 20081001 |
| [Value of targeted therapies for renal cell cancer]. | Der Urologe. Ausg. A 20081001 |
| Effects of peroxisome proliferator-activated receptor alpha (PPARalpha) agonists on leucine-induced phosphorylation of translational targets in C2C12 cells. | Biochimica et biophysica acta 20081001 |
| Mechanisms of Disease: survival benefit of temsirolimus validates a role for mTOR in the management of advanced RCC. | Nature clinical practice. Oncology 20081001 |
| Cytoplasmic and nuclear distribution of the protein complexes mTORC1 and mTORC2: rapamycin triggers dephosphorylation and delocalization of the mTORC2 components rictor and sin1. | Human molecular genetics 20081001 |
| Phospho-proteomic approach to identify new targets of leucine deprivation in muscle cells. | Analytical biochemistry 20081001 |
| Simultaneous islet and kidney transplantation in seven patients with type 1 diabetes and end-stage renal disease using a glucocorticoid-free immunosuppressive regimen with alemtuzumab induction. | Diabetes 20081001 |
| Randomized comparison of early inflammatory response after sirolimus-eluting stent vs bare metal stent implantation in native coronary lesions. | Clinica chimica acta; international journal of clinical chemistry 20081001 |
| Neuroprotection of rapamycin in lactacystin-induced neurodegeneration via autophagy enhancement. | Neurobiology of disease 20081001 |
| Prolonged response to temsirolimus in a pre-treated patient with metastatic renal cell carcinoma and poor performance status. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20081001 |
| Kaposi sarcoma in transplantation. | Transplantation reviews (Orlando, Fla.) 20081001 |
| Effect of mTOR inhibitor on body weight: from an experimental rat model to human transplant patients. | Transplant international : official journal of the European Society for Organ Transplantation 20081001 |
| Severe everolimus-associated pneumonitis in a renal transplant recipient. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001 |
| Bioabsorbable drug-eluting stents: the future of coronary angioplasty? | Nature clinical practice. Cardiovascular medicine 20081001 |
| Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation. | American journal of physiology. Endocrinology and metabolism 20081001 |
| [Targeted therapy - point blank or single shot]. | Der Urologe. Ausg. A 20081001 |
| Prolongation of corneal allograft survival by topical application of everolimus in experimental keratoplasty. | Ophthalmic research 20081001 |
| Everolimus- and zotarolimus-eluting stents for bare metal stent in-stent restenosis treatment: a prospective study. | Journal of interventional cardiology 20081001 |
| Morphological and biochemical characterization of basal and starvation-induced autophagy in isolated adult rat cardiomyocytes. | American journal of physiology. Heart and circulatory physiology 20081001 |
| Impact of current transplantation management on the development of cytomegalovirus disease after renal transplantation. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081001 |
| TOR regulates the subcellular distribution of DIM2, a KH domain protein required for cotranscriptional ribosome assembly and pre-40S ribosome export. | RNA (New York, N.Y.) 20081001 |
| Toll-like receptor-mediated induction of type I interferon in plasmacytoid dendritic cells requires the rapamycin-sensitive PI(3)K-mTOR-p70S6K pathway. | Nature immunology 20081001 |
| Prevention of cancer by inhibiting aging. | Cancer biology & therapy 20081001 |
| Persistent clinical impact of cytomegalovirus in organ transplantation. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20081001 |
| Sirolimus: a potential chemopreventive agent. | The Journal of investigative dermatology 20081001 |
| Insulin induces monocytic CXCL8 secretion by the mitogenic signalling pathway. | Cytokine 20081001 |
| Impact of mammalian target of rapamycin inhibition on lymphoid homing and tolerogenic function of nanoparticle-labeled dendritic cells following allogeneic hematopoietic cell transplantation. | Journal of immunology (Baltimore, Md. : 1950) 20081001 |
| Suboptimal percutaneous coronary intervention. | The American journal of cardiology 20081001 |
| Prognostic value of lesion classification for the clinical outcome after stent placement. | The American journal of cardiology 20081001 |
| Novel drugs for renal cell carcinoma. | Expert opinion on investigational drugs 20081001 |
| Complete versus incomplete revascularization in patients with multivessel disease undergoing percutaneous coronary intervention with drug-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001 |
| Sirolimus-eluting stents versus bare-metal stents in patients with in-stent restenosis: results of a pooled analysis of two randomized studies. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001 |
| Letter by Kounis et al regarding article, 'sirolimus-eluting stents suppress neointimal formation irrespective of metallic allergy'. | Circulation journal : official journal of the Japanese Circulation Society 20081001 |
| 'Neither horseshoes nor hand grenades'--does close count in percutaneous coronary revascularization? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001 |
| Repetita iuvant. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20081001 |
| [Systemic therapy of metastasizing renal cell carcinoma]. | Der Urologe. Ausg. A 20081001 |
| Recent advances in the treatment of renal cell carcinoma and the role of targeted therapies. | European journal of cancer (Oxford, England : 1990) 20081001 |
| Unprotected left main coronary artery bifurcation stenosis: impact of plaque debulking prior to single sirolimus-eluting stent implantation. | The Journal of invasive cardiology 20081001 |
| [Recent therapeutic progress in non-Hodgkin lymphoma: focusing on diffuse large B-cell lymphoma and follicular lymphoma]. | [Rinsho ketsueki] The Japanese journal of clinical hematology 20081001 |
| Targeted therapies for metastatic renal cell carcinoma: an overview of toxicity and dosing strategies. | The oncologist 20081001 |
| Robust and systematic drug screening method using chemical arrays and the protein library: identification of novel inhibitors of carbonic anhydrase II. | Bioscience, biotechnology, and biochemistry 20081001 |
| ABT-263 and rapamycin act cooperatively to kill lymphoma cells in vitro and in vivo. | Molecular cancer therapeutics 20081001 |
| Size matters (but so does time), and it's OK to be different. | Developmental cell 20081001 |
| The TOR pathway couples nutrition and developmental timing in Drosophila. | Developmental cell 20081001 |
| Systemic exposure of everolimus after stent implantation: a pharmacokinetic study. | American heart journal 20081001 |
| Avoidance of calcineurin inhibitors with use of proliferation signal inhibitors in de novo heart transplantation with renal failure. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20081001 |
| Heart transplantation under cyclosporine or tacrolimus combined with mycophenolate mofetil or everolimus. | Transplantation proceedings 20081001 |
| Rapamycin-induced cytotoxic signal transduction pathway. | Transplantation proceedings 20081001 |
| Rapamycin and cyclosporine have different effects on expression of Ang-1 and Ang-2 and Tie2 in rat renal allograft with chronic allograft nephropathy. | Transplantation proceedings 20081001 |
| Sirolimus-eluting and paclitaxel-eluting stents for the treatment of coronary bifurcations. | American heart journal 20081001 |
| Regression of subependymal giant cell astrocytoma with rapamycin in tuberous sclerosis complex. | Journal of child neurology 20081001 |
| [Effect of chemotherapy with cisplatin and rapamycin against Hep-2 cells in vitro]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20081001 |
| Combination treatment with plasmapheresis and sirolimus does not seem to benefit nephrogenic systemic fibrosis. | The International journal of artificial organs 20081001 |
| mTOR inhibition reverses acquired endocrine therapy resistance of breast cancer cells at the cell proliferation and gene-expression levels. | Cancer science 20081001 |
| Status of drug-eluting coronary stents. | Medicine and health, Rhode Island 20081001 |
| Out with the old, in with the new: immunosuppression minimization in children. | Current opinion in organ transplantation 20081001 |
| Therapies for interstitial lung disease: past, present and future. | Therapeutic advances in respiratory disease 20081001 |
| [Blockage of mTOR signaling pathway by rapamycin contributes to inhibition of tumor cell proliferation in ALK-positive lymphoid cell strains]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20081001 |
| A randomized, controlled, multicenter trial to evaluate the safety and efficacy of zotarolimus- versus paclitaxel-eluting stents in de novo occlusive lesions in coronary arteries The ZoMaxx I trial. | JACC. Cardiovascular interventions 20081001 |
| The process of bringing new drug-eluting stents to market will they see the light of day? | JACC. Cardiovascular interventions 20081001 |
| Differential healing responses in polymer- and nonpolymer-based sirolimus-eluting stents. | JACC. Cardiovascular interventions 20081001 |
| Preliminary results of the hydroxyapatite nonpolymer-based sirolimus-eluting stent for the treatment of single de novo coronary lesions a first-in-human analysis of a third-generation drug-eluting stent system. | JACC. Cardiovascular interventions 20081001 |
| Tissue sirolimus levels of distal vessel, stented myocardium, and distal myocardium. | JACC. Cardiovascular interventions 20081001 |
| Primary percutaneous coronary intervention with drug-eluting stents: another chapter in the stent controversy. | Circulation. Cardiovascular interventions 20081001 |
| Primary percutaneous coronary intervention for acute myocardial infarction: long-term outcome after bare metal and drug-eluting stent implantation. | Circulation. Cardiovascular interventions 20081001 |
| Incidence and correlates of drug-eluting stent thrombosis in routine clinical practice. 4-year results from a large 2-institutional cohort study. | Journal of the American College of Cardiology 20080930 |
| Biolimus-eluting stent with biodegradable polymer versus sirolimus-eluting stent with durable polymer for coronary revascularisation (LEADERS): a randomised non-inferiority trial. | Lancet (London, England) 20080927 |
| Drug-eluting stents: is new necessarily better? | Lancet (London, England) 20080927 |
| Calcineurin inhibitor sparing in renal transplantation. | Transplantation 20080927 |
| The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes. | Molecular cell 20080926 |
| Angioscopic findings of delayed healing at sites of sirolimus-eluting stent overlap after 21-month implantation. | International journal of cardiology 20080916 |
| Translational control of c-MYC by rapamycin promotes terminal myeloid differentiation. | Blood 20080915 |
| Defects in skin gamma delta T cell function contribute to delayed wound repair in rapamycin-treated mice. | Journal of immunology (Baltimore, Md. : 1950) 20080915 |
| Safety of drug-eluting stents in patients with left ventricular dysfunction undergoing percutaneous coronary intervention. | The American journal of cardiology 20080915 |
| Enhancing mammalian target of rapamycin (mTOR)-targeted cancer therapy by preventing mTOR/raptor inhibition-initiated, mTOR/rictor-independent Akt activation. | Cancer research 20080915 |
| FBXW7 targets mTOR for degradation and cooperates with PTEN in tumor suppression. | Science (New York, N.Y.) 20080912 |
| Efficacy of RAD001 (everolimus) and octreotide LAR in advanced low- to intermediate-grade neuroendocrine tumors: results of a phase II study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080910 |
| Rapamycin down-regulates LDL-receptor expression independently of SREBP-2. | Biochemical and biophysical research communications 20080905 |
| CCL2 protects prostate cancer PC3 cells from autophagic death via phosphatidylinositol 3-kinase/AKT-dependent survivin up-regulation. | The Journal of biological chemistry 20080905 |
| Long-term efficacy and safety of Chinese made sirolimus eluting stents: results, including off label usage, from two centres over three years. | Chinese medical journal 20080905 |
| Inhibition of mTOR restores cisplatin sensitivity through down-regulation of growth and anti-apoptotic proteins. | European journal of pharmacology 20080904 |
| Anti-tumor effect of honokiol alone and in combination with other anti-cancer agents in breast cancer. | European journal of pharmacology 20080904 |
| Rapamycin reduces VEGF expression in retinal pigment epithelium (RPE) and inhibits RPE-induced sprouting angiogenesis in vitro. | FEBS letters 20080903 |
| Major treatment improvements encourage kidney cancer researchers to seek further gains. | Journal of the National Cancer Institute 20080903 |
| SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth. | Cell metabolism 20080903 |
| Inhibition of mTORC1 leads to MAPK pathway activation through a PI3K-dependent feedback loop in human cancer. | The Journal of clinical investigation 20080902 |
| The impact of lesion length and vessel size on outcomes after sirolimus-eluting stent implantation for in-stent restenosis. | Heart (British Cardiac Society) 20080901 |
| Introducing the first polymer-free leflunomide eluting stent. | Atherosclerosis 20080901 |
| Combination antifungal therapy involving amphotericin B, rapamycin and 5-fluorocytosine using PEG-phospholipid micelles. | Pharmaceutical research 20080901 |
| Rapamycin attenuates the severity of established nephritis in lupus-prone NZB/W F1 mice. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080901 |
| Use of sirolimus in IPEX and IPEX-like children. | Journal of clinical immunology 20080901 |
| Kaposi's sarcoma and mTOR: a crossroad between viral infection neoangiogenesis and immunosuppression. | Transplant international : official journal of the European Society for Organ Transplantation 20080901 |
| The alpha4-containing form of protein phosphatase 2A in liver and hepatic cells. | Journal of cellular biochemistry 20080901 |
| Rapamycin monotherapy in patients with type 1 diabetes modifies CD4+CD25+FOXP3+ regulatory T-cells. | Diabetes 20080901 |
| Maternal protein restriction during early lactation induces GLUT4 translocation and mTOR/Akt activation in adipocytes of adult rats. | American journal of physiology. Endocrinology and metabolism 20080901 |
| Lifetime cost-effectiveness of calcineurin inhibitor withdrawal after de novo renal transplantation. | Journal of the American Society of Nephrology : JASN 20080901 |
| Late and very late stent thrombosis following drug-eluting stent implantation in unprotected left main coronary artery: a multicentre registry. | European heart journal 20080901 |
| Autophagy-inducing agents augment the antitumor effect of telerase-selve oncolytic adenovirus OBP-405 on glioblastoma cells. | Gene therapy 20080901 |
| Mammalian target of rapamycin (mTOR) is involved in the neuronal differentiation of neural progenitors induced by insulin. | Molecular and cellular neurosciences 20080901 |
| Huntington's disease: degradation of mutant huntingtin by autophagy. | The FEBS journal 20080901 |
| A GSK-3/TSC2/mTOR pathway regulates glucose uptake and GLUT1 glucose transporter expression. | American journal of physiology. Cell physiology 20080901 |
| Late drug-eluting stent thrombosis in unprotected left main coronary artery lesions--sometimes possible, but rarely definite or probable. | European heart journal 20080901 |
| Targeted therapy in renal cell carcinoma. | Current opinion in urology 20080901 |
| Positive reasons for publishing negative findings. | The American journal of gastroenterology 20080901 |
| A multicenter, randomized, double-blind trial of everolimus versus azathioprine and placebo to maintain steroid-induced remission in patients with moderate-to-severe active Crohn's disease. | The American journal of gastroenterology 20080901 |
| Strut fracture: a further concern with drug-eluting stents. | Journal of cardiovascular medicine (Hagerstown, Md.) 20080901 |
| Small molecule enhancers of autophagy for neurodegenerative diseases. | Molecular bioSystems 20080901 |
| Everolimus (RAD001) and anti-angiogenic cyclophosphamide show long-term control of gastric cancer growth in vivo. | Cancer biology & therapy 20080901 |
| Sirolimus-induced aphthous ulcers which disappeared with conversion to everolimus. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20080901 |
| Use of sirolimus (rapamycin) to treat refractory Crohn's disease. | Gut 20080901 |
| Ras-mediated up-regulation of survivin expression in cytokine-dependent murine pro-B lymphocytic cells. | The Tohoku journal of experimental medicine 20080901 |
| One-year clinical outcomes of dialysis patients after implantation with sirolimus-eluting coronary stents. | Circulation journal : official journal of the Japanese Circulation Society 20080901 |
| Urothelial carcinoma in kidney transplant recipients: conversion from calcineurin inhibitor to proliferation signal inhibitor? | American journal of kidney diseases : the official journal of the National Kidney Foundation 20080901 |
| Involvement of insulin in early development of mouse one-cell stage embryos. | Science in China. Series C, Life sciences 20080901 |
| Pharmacodynamic-guided modified continuous reassessment method-based, dose-finding study of rapamycin in adult patients with solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080901 |
| Chemoprevention and treatment of experimental Cowden's disease by mTOR inhibition with rapamycin. | Cancer research 20080901 |
| Safety of drug-coated stents. | Expert opinion on drug safety 20080901 |
| Late unilateral pulmonary edema in single lung transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080901 |
| mTOR inhibitors and unilateral edema. | Revista espanola de cardiologia 20080901 |
| Novel therapeutic options in metastatic renal cancer - review and post ASCO 2007 update. | Reviews on recent clinical trials 20080901 |
| Symptomatic pulmonary allograft Kaposi's sarcoma in two lung transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080901 |
| Impact of variability of sirolimus trough level on chronic allograft nephropathy. | Transplantation proceedings 20080901 |
| De novo sirolimus-based regimen in Thai renal transplant recipients. | Transplantation proceedings 20080901 |
| Sirolimus conversion experience in a single center. | Transplantation proceedings 20080901 |
| Everolimus with reduced-dose cyclosporine in de novo renal transplant recipients: Philippine experience. | Transplantation proceedings 20080901 |
| Possible mechanism by which rapamycin increases cyclosporine nephrotoxicity. | Transplantation proceedings 20080901 |
| Sirolimus does not absolutely abolish the occurrence/recurrence of urothelial carcinoma in renal transplant recipients. | Transplantation proceedings 20080901 |
| Late spontaneous kidney graft decapsulation after administration of sirolimus in a recipient with chronic hepatitis B and C infection: a case report. | Transplantation proceedings 20080901 |
| Sirolimus used during pregnancy in a living related renal transplant recipient: a case report. | Transplantation proceedings 20080901 |
| Long-term efficacy and safety of sirolimus-eluting vs bare-metal stents. | Connecticut medicine 20080901 |
| [Renal cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20080901 |
| Pilot study of rapamycin in patients with hormone-refractory prostate cancer. | Clinical genitourinary cancer 20080901 |
| NCCN Task Force Report: mTOR inhibition in solid tumors. | Journal of the National Comprehensive Cancer Network : JNCCN 20080901 |
| Clinical investigations in T-cell and NK-cell non-Hodgkin lymphoma. | Clinical advances in hematology & oncology : H&O 20080901 |
| Use of sirolimus in a case of severe paraquat poisoning. | Clinical toxicology (Philadelphia, Pa.) 20080901 |
| Complete fracture and restenosis of sirolimus-eluting stent in ostial saphenous vein graft. | International journal of cardiology 20080829 |
| Drug eluting stents in patients with diabetes. | BMJ (Clinical research ed.) 20080829 |
| Rapamycin inhibits F-actin reorganization and phosphorylation of focal adhesion proteins. | Oncogene 20080828 |
| Reduction in erythropoietin resistance after conversion from sirolimus to enteric coated mycophenolate sodium. | Transplantation 20080827 |
| Improved renal function, with similar proteinuria, after two years of early tacrolimus withdrawal from a regimen of sirolimus plus tacrolimus. | Transplantation 20080827 |
| A randomized comparison of sirolimus- versus Paclitaxel-eluting stent implantation in patients with diabetes mellitus. | Journal of the American College of Cardiology 20080826 |
| Angioscopic comparison of neointimal coverage between zotarolimus- and sirolimus-eluting stents. | Journal of the American College of Cardiology 20080826 |
| Heterogeneous nuclear ribonucleoprotein A1 regulates cyclin D1 and c-myc internal ribosome entry site function through Akt signaling. | The Journal of biological chemistry 20080822 |
| Firebird and cypher sirolimus-eluting stents and bare metal stents in treatment of very long coronary lesions. | Chinese medical journal 20080820 |
| Quantitation of autophagy by luciferase release assay. | Autophagy 20080816 |
| Frequency modulation of synchronized Ca(2+) spikes in cultured hippocampal networks through mTOR. | Neuroscience letters 20080815 |
| Effect of rapamycin alone and in combination with sorafenib in an orthotopic model of human hepatocellular carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080815 |
| Prolongation of cardiac allograft survival by rapamycin and the invariant natural killer T cell glycolipid agonist OCH. | Transplantation 20080815 |
| S6K1 plays a key role in glial transformation. | Cancer research 20080815 |
| Tumorigenic activity and therapeutic inhibition of Rheb GTPase. | Genes & development 20080815 |
| Watchdog set to reject four drugs for kidney cancer on the NHS. | BMJ (Clinical research ed.) 20080814 |
| Progression-free survival as endpoint in metastatic RCC? | Lancet (London, England) 20080809 |
| Efficacy of everolimus in advanced renal cell carcinoma: a double-blind, randomised, placebo-controlled phase III trial. | Lancet (London, England) 20080809 |
| A strategy to offset the extra cost of sirolimus-eluting stent in patients undergoing intervention for acute myocardial infarction. | International journal of cardiology 20080801 |
| Activation of the mTOR signaling pathway in breast cancer and its correlation with the clinicopathologic variables. | Breast cancer research and treatment 20080801 |
| Everolimus in patients with rheumatoid arthritis receiving concomitant methotrexate: a 3-month, double-blind, randomised, placebo-controlled, parallel-group, proof-of-concept study. | Annals of the rheumatic diseases 20080801 |
| Sirolimus and regression of Kaposi's sarcoma in immunosuppressed transplant patient. | Journal of the European Academy of Dermatology and Venereology : JEADV 20080801 |
| Antineoplastic effect of rapamycin is potentiated by inhibition of IRS-1 signaling in prostate cancer cells xenografts. | Journal of cancer research and clinical oncology 20080801 |
| Combined inhibition of MAPK and mTOR signaling inhibits growth, induces cell death, and abrogates invasive growth of melanoma cells. | The Journal of investigative dermatology 20080801 |
| The PI 3-kinase and mTOR signaling pathways are important modulators of epithelial tubule formation. | Journal of cellular physiology 20080801 |
| Temsirolimus safety profile and management of toxic effects in patients with advanced renal cell carcinoma and poor prognostic features. | Annals of oncology : official journal of the European Society for Medical Oncology 20080801 |
| Hypoxia-inducible factor-2alpha: effect on radiation sensitivity and differential regulation by an mTOR inhibitor. | BJU international 20080801 |
| The macrolide everolimus forms an unusual metabolite in animals and humans: identification of a phosphocholine ester. | Drug metabolism and disposition: the biological fate of chemicals 20080801 |
| mTOR in squamous cell carcinoma of the oesophagus: a potential target for molecular therapy? | Journal of clinical pathology 20080801 |
| Differential effects of rapamycin in anti-GBM glomerulonephritis. | Journal of the American Society of Nephrology : JASN 20080801 |
| Stimulation of autophagy suppresses the intracellular survival of Burkholderia pseudomallei in mammalian cell lines. | Autophagy 20080801 |
| What controls TOR? | IUBMB life 20080801 |
| Localization of autophagy-related proteins in yeast using a versatile plasmid-based resource of fluorescent protein fusions. | Autophagy 20080801 |
| Temsirolimus in metastatic renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20080801 |
| mTOR inhibitor monotherapy is insufficient to suppress viremia and disease progression in Epstein-Barr virus-driven lymphoproliferative disorders (EBV-LPD). | American journal of hematology 20080801 |
| Low-dose, single-agent temsirolimus for relapsed mantle cell lymphoma: a phase 2 trial in the North Central Cancer Treatment Group. | Cancer 20080801 |
| The mTOR inhibitor rapamycin significantly improves facial angiofibroma lesions in a patient with tuberous sclerosis. | The British journal of dermatology 20080801 |
| Randomized trial of three rapamycin-eluting stents with different coating strategies for the reduction of coronary restenosis. | European heart journal 20080801 |
| The potential clinical utility of intravascular ultrasound guidance in patients undergoing percutaneous coronary intervention with drug-eluting stents. | European heart journal 20080801 |
| The effect of rapamycin on DNA synthesis in multiple tissues from late gestation fetal and postnatal rats. | American journal of physiology. Cell physiology 20080801 |
| Vascular endothelial growth factor protein levels and gene expression in peripheral monocytes after stenting: a randomized comparative study of sirolimus-eluting and bare-metal stents. | European heart journal 20080801 |
| Patient selection critical for calcineurin inhibitor withdrawal in pediatric kidney transplantation. | Pediatric transplantation 20080801 |
| Hepatic translation control in the late-gestation fetal rat. | American journal of physiology. Regulatory, integrative and comparative physiology 20080801 |
| Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis. | Nature medicine 20080801 |
| Effect of sirolimus on left ventricular hypertrophy in kidney transplant recipients: a 1-year nonrandomized controlled trial. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20080801 |
| Biodegradable coating for drug-eluting stents--more than a facelift? | European heart journal 20080801 |
| Combination of rapamycin and 17-allylamino-17-demethoxygeldanamycin abrogates Akt activation and potentiates mTOR blockade in breast cancer cells. | Anti-cancer drugs 20080801 |
| In-vitro synergism of m-TOR inhibitors, statins, and classical chemotherapy: potential implications in acute leukemia. | Anti-cancer drugs 20080801 |
| Sirolimus-eluting stent implantation for bare-metal in-stent restenosis: is there any evidence for a late catch-up phenomenon? | Journal of cardiovascular medicine (Hagerstown, Md.) 20080801 |
| Clinical-grade preparation of human natural regulatory T-cells encoding the thymidine kinase suicide gene as a safety gene. | The journal of gene medicine 20080801 |
| The MAP kinase-activated protein kinase Rck2p plays a role in rapamycin sensitivity in Saccharomyces cerevisiae and Candida albicans. | FEMS yeast research 20080801 |
| Nutrient content of diet affects the signaling activity of the insulin/target of rapamycin/p70 S6 kinase pathway in the African malaria mosquito Anopheles gambiae. | Journal of insect physiology 20080801 |
| Two-year outcome of patients treated with sirolimus- versus paclitaxel-eluting stents in an unselected population with coronary artery disease (from the REWARDS Registry). | The American journal of cardiology 20080801 |
| Intravascular ultrasound evaluation of optimal drug-eluting stent expansion after poststent balloon dilation using a noncompliant balloon versus a semicompliant balloon (from the Poststent Optimal Stent Expansion Trial [POET]). | The American journal of cardiology 20080801 |
| Angiographic patterns of drug-eluting stent restenosis and one-year outcomes after treatment with repeated percutaneous coronary intervention. | The American journal of cardiology 20080801 |
| Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080801 |
| Sirolimus in combination with tacrolimus in allogeneic stem cell transplantation--timing and conditioning regimen may be crucial. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080801 |
| Development of a predictive limited sampling strategy for estimation of mycophenolic acid area under the concentration time curve in patients receiving concomitant sirolimus or cyclosporine. | Therapeutic drug monitoring 20080801 |
| Biodegradable polymers--are they the answer to late stent thrombosis? Too early to tell. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801 |
| Novel bioabsorbable salicylate-based polymer as a drug-eluting stent coating. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801 |
| Early days of an ingenious aspirin and sirolimus-eluting stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801 |
| Long-term clinical, angiographic, and intravascular ultrasound outcomes of biodegradable polymer-coated sirolimus-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801 |
| Optical coherence tomography: high resolution intravascular imaging to evaluate vascular healing after coronary stenting. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080801 |
| Sirolimus amelioration of clinical symptoms of recurrent lymphangioleiomyomatosis after living-donor lobar lung transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080801 |
| Evaluation of a deuterium-labeled internal standard for the measurement of sirolimus by high-throughput HPLC electrospray ionization tandem mass spectrometry. | Clinical chemistry 20080801 |
| Corneal permeation studies of everolimus microemulsion. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080801 |
| A small molecule-directed approach to control protein localization and function. | Yeast (Chichester, England) 20080801 |
| Evaluation of the mammalian target of rapamycin pathway and the effect of rapamycin on target expression and cellular proliferation in osteosarcoma cells from dogs. | American journal of veterinary research 20080801 |
| Temsirolimus, an mTOR inhibitor for treatment of patients with advanced renal cell carcinoma. | Clinical journal of oncology nursing 20080801 |
| Two-year intravascular ultrasound observations in diabetic patients treated with single and double dose sirolimus-eluting stents: results of the double dose diabetes (3D) study. | The Journal of invasive cardiology 20080801 |
| Coexistent in-stent restenosis, late incomplete stent apposition and mural thrombus in a zotarolimus-eluting stent. | The Journal of invasive cardiology 20080801 |
| 'Black hole' restenosis after sirolimus-eluting stent implantation. | The Journal of invasive cardiology 20080801 |
| Oral sirolimus for prevention of recurrent infrainguinal arterial obstructions after surgical and endovascular revascularizations. | VASA. Zeitschrift fur Gefasskrankheiten 20080801 |
| Rapamycin modulates the maturation of rat bone marrow-derived dendritic cells. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20080801 |
| [Can defective TGF-Beta signaling be an Achilles heel in human cancer?]. | Ai zheng = Aizheng = Chinese journal of cancer 20080801 |
| In-stent restenosis in bare metal stents versus sirolimus-eluting stents after primary coronary intervention for acute myocardial infarction and subsequent transcoronary transplantation of autologous stem cells. | Clinical cardiology 20080801 |
| Aging, stem cells, and mammalian target of rapamycin: a prospect of pharmacologic rejuvenation of aging stem cells. | Rejuvenation research 20080801 |
| Cotylenin A, a new differentiation inducer, and rapamycin cooperatively inhibit growth of cancer cells through induction of cyclin G2. | Cancer science 20080801 |
| Inference of protein complex activities from chemical-genetic profile and its applications: predicting drug-target pathways. | PLoS computational biology 20080801 |
| What the similarities of specific polycystic liver and kidney diseases can teach us about both. | Nephrology news & issues 20080801 |
| Conversion from sirolimus to everolimus in maintenance renal transplant recipients within a calcineurin inhibitor-free regimen: results of a 6-month pilot study. | Clinical nephrology 20080801 |
| [Effect of rapamycin in inducing naïve murine effector T cell convert to regulatory T cell]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20080801 |
| [Rapamycin-loaded poly (lactic-co-glycolic) acid nanoparticles for intraarterial local drug delivery: preparation, characterization, and in vitro/in vivo release]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20080801 |
| Clinical outcomes of sirolimus with eluting stent implantation in coronary artery disease. | JPMA. The Journal of the Pakistan Medical Association 20080801 |
| One year results of a new in situ length-adjustable stent platform with a biodegradable biolimus A9 eluting polymer: results of the CUSTOM-II trial. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801 |
| Safety in simple versus complex stenting of coronary artery bifurcation lesions. The nordic bifurcation study 14-month follow-up results. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801 |
| Elective implantation of sirolimus-eluting stents for bifurcated and non-bifurcated unprotected left main coronary artery lesions: clinical outcomes at one year. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080801 |
| 3-year follow-up of the SISR (Sirolimus-Eluting Stents Versus Vascular Brachytherapy for In-Stent Restenosis) trial. | JACC. Cardiovascular interventions 20080801 |
| Lack of association between large angiographic late loss and low risk of in-stent thrombus: angioscopic comparison between paclitaxel- and sirolimus-eluting stents. | Circulation. Cardiovascular interventions 20080801 |
| Antidepressive-like effects of rapamycin in animal models: Implications for mTOR inhibition as a new target for treatment of affective disorders. | Brain research bulletin 20080730 |
| Endothelial cell recovery between comparator polymer-based drug-eluting stents. | Journal of the American College of Cardiology 20080729 |
| Beneficial effect of omega-3 fatty acids on sirolimus- or everolimus-induced hypertriglyceridemia in heart transplant recipients. | Transplantation 20080727 |
| Clinical trials probe new therapies for some difficult-to-treat cancers. | JAMA 20080723 |
| Anti-proinflammatory effects of sirolimus on human islet preparations. | Transplantation 20080715 |
| Chronic kidney disease--a common and serious complication after intestinal transplantation. | Transplantation 20080715 |
| Prolongation of cardiac and islet allograft survival by a blocking hamster anti-mouse CXCR3 monoclonal antibody. | Transplantation 20080715 |
| Sirolimus (rapamycin) induced proteinuria in a patient undergoing allogeneic hematopoietic stem cell transplant. | Transplantation 20080715 |
| Sirolimus in metatastic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080710 |
| [Effects of sirolimus-eluting stent and the paclitaxel-eluting stent: a three-year follow-up study]. | Zhonghua yi xue za zhi 20080708 |
| Simultaneous subacute stent thrombosis after implantation of sirolimus-eluting stent and bare-metal stent. | International journal of cardiology 20080704 |
| Suppression of PTEN function increases breast cancer chemotherapeutic drug resistance while conferring sensitivity to mTOR inhibitors. | Oncogene 20080703 |
| Localization of polypyrimidine-tract-binding protein is involved in the regulation of albumin synthesis by branched-chain amino acids in HepG2 cells. | The Journal of nutritional biochemistry 20080701 |
| Antiproliferative effects of rapamycin as a single agent and in combination with carboplatin and paclitaxel in head and neck cancer cell lines. | Cancer chemotherapy and pharmacology 20080701 |
| Sirolimus enhances the effect of apoptotic cell infusion on hematopoietic engraftment and tolerance induction. | Leukemia 20080701 |
| Incisional surgical site infection in kidney transplantation. | Urology 20080701 |
| Systemic inhibition of mammalian target of rapamycin inhibits fear memory reconsolidation. | Neurobiology of learning and memory 20080701 |
| Treatment of in-stent restenosis with sirolimus-eluting-stents: results from the prospective German Cypher stent registry. | Clinical research in cardiology : official journal of the German Cardiac Society 20080701 |
| Introduction: new insights, treatments, and management strategies for ADPKD. | Clinical journal of the American Society of Nephrology : CJASN 20080701 |
| Sirolimus is associated with new-onset diabetes in kidney transplant recipients. | Journal of the American Society of Nephrology : JASN 20080701 |
| Prospective randomized comparison of sirolimus- versus paclitaxel-eluting stents for the treatment of acute ST-elevation myocardial infarction: pROSIT trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080701 |
| Fluvastatin synergistically improves the antiproliferative effect of everolimus on rat smooth muscle cells by altering p27Kip1/cyclin E expression. | Molecular pharmacology 20080701 |
| Autophagy upregulation by inhibitors of caspase-3 and mTOR enhances radiotherapy in a mouse model of lung cancer. | Autophagy 20080701 |
| Caveolin-1 increases basal and TGF-beta1-induced expression of type I procollagen through PI-3 kinase/Akt/mTOR pathway in human dermal fibroblasts. | Cellular signalling 20080701 |
| Leucine induces phosphorylation and activation of p70S6K in cortical neurons via the system L amino acid transporter. | Journal of neurochemistry 20080701 |
| Rapamycin affects early fracture healing in mice. | British journal of pharmacology 20080701 |
| Phase I, pharmacokinetic and pharmacodynamic study of the anti-insulinlike growth factor type 1 Receptor monoclonal antibody CP-751,871 in patients with multiple myeloma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080701 |
| Inhibition of mTOR in combination with doxorubicin in an experimental model of hepatocellular carcinoma. | Journal of hepatology 20080701 |
| Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma. | Journal of hepatology 20080701 |
| Glibenclamide activates translation in rat pancreatic beta cells through calcium-dependent mTOR, PKA and MEK signalling pathways. | Diabetologia 20080701 |
| Multivariate analysis applied to the study of spatial distributions found in drug-eluting stent coatings by confocal Raman microscopy. | Analytical chemistry 20080701 |
| Mammalian target of rapamycin inhibitor dyslipidemia in kidney transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080701 |
| Sirolimus may reduce fertility in male renal transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080701 |
| Caffeine extends yeast lifespan by targeting TORC1. | Molecular microbiology 20080701 |
| Evaluation of the variables characterized by significant discriminating power in the application of SIMCA classification method to proteomic studies. | Journal of proteome research 20080701 |
| Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model. | The Journal of clinical investigation 20080701 |
| Sirolimus-associated pneumonitis in heart transplant recipients. | The Annals of pharmacotherapy 20080701 |
| Drug-eluting stents in ST elevation myocardial infarction: In light of the PROSIT trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080701 |
| IL-1beta-driven ST2L expression promotes maturation resistance in rapamycin-conditioned dendritic cells. | Journal of immunology (Baltimore, Md. : 1950) 20080701 |
| Intravascular ultrasound assessment of expansion of the sirolimus-eluting (cypher select) and paclitaxel-eluting (Taxus Express-2) stent in patients with diabetes mellitus. | The American journal of cardiology 20080701 |
| Comparison of neointimal coverage by optical coherence tomography of a sirolimus-eluting stent versus a bare-metal stent three months after implantation. | The American journal of cardiology 20080701 |
| Safety and efficacy of sirolimus-eluting stent in patients with acute coronary syndrome undergoing emergency procedure. | Circulation journal : official journal of the Japanese Circulation Society 20080701 |
| Very late stent thrombosis associated with multiple stent fractures and peri-stent aneurysm formation after sirolimus-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20080701 |
| Diabetes after transplantation and sirolimus: what's the connection? | Journal of the American Society of Nephrology : JASN 20080701 |
| De-novo [corrected] post renal transplantation inflammatory bowel disease. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20080701 |
| New drugs08, part 2. | Nursing 20080701 |
| Everolimus-related pulmonary toxicity in heart transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080701 |
| Renal cell carcinoma: the translation of molecular biology into new treatments, new patient outcomes, and nursing implications. | Oncology nursing forum 20080701 |
| Corticosteroid interactions with cyclosporine, tacrolimus, mycophenolate, and sirolimus: fact or fiction? | The Annals of pharmacotherapy 20080701 |
| [Targeted therapy for locally advanced and/or metastatic bladder cancer]. | Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20080701 |
| Genetic interactions of MAF1 identify a role for Med20 in transcriptional repression of ribosomal protein genes. | PLoS genetics 20080701 |
| Angiographic time course of in-stent restenosis with zotarolimus drug-eluting stents. | The Canadian journal of cardiology 20080701 |
| Formation of tissue factor-factor VIIa-factor Xa complex induces activation of the mTOR pathway which regulates migration of human breast cancer cells. | Thrombosis and haemostasis 20080701 |
| Variability in the prevalence of acute bronchoresponsiveness in different populations of patients with lymphangioleiomyomatosis. | Chest 20080701 |
| Favorable results of concomitant tacrolimus and sirolimus therapy in Taiwanese renal transplant recipients at 12 months. | Journal of the Formosan Medical Association = Taiwan yi zhi 20080701 |
| [Effeet of rapamycin on mTOR and eIF-4E expression in coxsackievirus B3-induced rat myocardial cells]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20080701 |
| Drug eluting stents: friend or foe? A review of cellular mechanisms behind the effects of Paclitaxel and sirolimus eluting stents. | Current drug metabolism 20080701 |
| Oral everolimus inhibits neointimal proliferation in prosthetic pulmonary valved stents in pigs. | The Journal of heart valve disease 20080701 |
| [Comparison of different drug-eluting stents in the treatment of coronary artery disease: a single center four-year clinical follow-up]. | Zhonghua nei ke za zhi 20080701 |
| Comparison of vascular response after sirolimus-eluting stent implantation between patients with unstable and stable angina pectoris: a serial optical coherence tomography study. | JACC. Cardiovascular imaging 20080701 |
| Does underlying plaque morphology play a role in vessel healing after drug-eluting stent implantation? | JACC. Cardiovascular imaging 20080701 |
| Cyclosporine A and Rapamycin induce in vitro cholesteryl ester transfer protein activity, and suppress lipoprotein lipase activity in human plasma. | International journal of pharmaceutics 20080624 |
| Clinical efficacy of drug-eluting stents in diabetic patients: a meta-analysis. | Journal of the American College of Cardiology 20080624 |
| Novel genetically encoded biosensors using firefly luciferase. | ACS chemical biology 20080620 |
| Delivery of rapamycin-loaded nanoparticle down regulates ICAM-1 expression and maintains an immunosuppressive profile in human CD34+ progenitor-derived dendritic cells. | Journal of biomedical materials research. Part A 20080615 |
| Development of a novel biocompatible polymer system for extended drug release in a next-generation drug-eluting stent. | Journal of biomedical materials research. Part A 20080615 |
| Impact of stent deployment procedural factors on long-term effectiveness and safety of sirolimus-eluting stents (final results of the multicenter prospective STLLR trial). | The American journal of cardiology 20080615 |
| Protein phosphatase 2A and rapamycin regulate the nuclear localization and activity of the transcription factor GLI3. | Cancer research 20080615 |
| PTEN loss does not predict for response to RAD001 (Everolimus) in a glioblastoma orthotopic xenograft test panel. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080615 |
| The forgotten player of in-stent restenosis: endothelial dysfunction. | International journal of cardiology 20080606 |
| Reduced exposure to calcineurin inhibitors in renal transplantation. | The New England journal of medicine 20080605 |
| Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus. | British journal of cancer 20080603 |
| Differential effects of drug-eluting stents on local endothelium-dependent coronary vasomotion. | Journal of the American College of Cardiology 20080603 |
| Sirolimus-induced vascular dysfunction. Increased mitochondrial and nicotinamide adenosine dinucleotide phosphate oxidase-dependent superoxide production and decreased vascular nitric oxide formation. | Journal of the American College of Cardiology 20080603 |
| Endothelial dysfunction associated with drug-eluting stents what, where, when, and how? | Journal of the American College of Cardiology 20080603 |
| Contribution of organized thrombus to in-stent restenosis after sirolimus-eluting stent implantation: optical coherence tomography findings. | European heart journal 20080601 |
| Sirolimus and intraoperative hyperthermic peritoneal chemoperfusion with mitomycin-C do not impair healing of bowel anastomoses. | Transplant international : official journal of the European Society for Organ Transplantation 20080601 |
| In human endothelial cells rapamycin causes mTORC2 inhibition and impairs cell viability and function. | Cardiovascular research 20080601 |
| Immunosuppressive medications, clinical and metabolic parameters in new-onset diabetes mellitus after kidney transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20080601 |
| Everolimus for refractory Crohn's disease: a case report. | Inflammatory bowel diseases 20080601 |
| Inhibition of mTOR by sirolimus induces remission of post-transplant lymphoproliferative disorders. | Transplant international : official journal of the European Society for Organ Transplantation 20080601 |
| Combination of rapamycin and IL-2 increases de novo induction of human CD4(+)CD25(+)FOXP3(+) T cells. | Journal of autoimmunity 20080601 |
| Response of human renal tubular cells to cyclosporine and sirolimus: a toxicogenomic study. | Toxicology and applied pharmacology 20080601 |
| Long-term efficacy and safety of a calcineurin inhibitor-free regimen in live-donor renal transplant recipients. | Journal of the American Society of Nephrology : JASN 20080601 |
| Effect of Paclitaxel-eluting versus sirolimus-eluting stents on coronary restenosis in Korean diabetic patients. | Journal of interventional cardiology 20080601 |
| Graft rejection: pharmacogenetic analysis or drug anamnesis? | British journal of clinical pharmacology 20080601 |
| Simultaneous quantification of cyclosporine, tacrolimus, sirolimus and everolimus in whole blood by liquid chromatography-electrospray mass spectrometry. | Clinical biochemistry 20080601 |
| RAD001 (Everolimus) inhibits growth of prostate cancer in the bone and the inhibitory effects are increased by combination with docetaxel and zoledronic acid. | The Prostate 20080601 |
| Lithium-mediated suppression of morphogenesis and growth in Candida albicans. | FEMS yeast research 20080601 |
| Difficult stent delivery: use of an aspiration catheter as a 'sheath'. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601 |
| Comparison of Akt/mTOR signaling in primary breast tumors and matched distant metastases. | Cancer 20080601 |
| Long-term clinical outcomes of real-world experience using sirolimus-eluting stents in saphenous vein graft disease. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601 |
| Safety of drug-eluting stents. | Nature clinical practice. Cardiovascular medicine 20080601 |
| Rapamycin conditionally inhibits Hsp90 but not Hsp70 mRNA translation in Drosophila: implications for the mechanisms of Hsp mRNA translation. | Cell stress & chaperones 20080601 |
| Regulated insulin delivery from human epidermal cells reverses hyperglycemia. | Molecular therapy : the journal of the American Society of Gene Therapy 20080601 |
| Rapamycin treatment for a child with germline PTEN mutation. | Nature clinical practice. Oncology 20080601 |
| Pharmacodynamic effects of everolimus on anti-CD3 antibody-stimulated T-lymphocyte proliferation and interleukin-10 synthesis in stable kidney-transplant patients. | Cytokine 20080601 |
| Expression of c-Kit isoforms in multiple myeloma: differences in signaling and drug sensitivity. | Haematologica 20080601 |
| An Epstein-Barr virus positive natural killer lymphoma xenograft derived for drug testing. | Leukemia & lymphoma 20080601 |
| Autophagy activation by rapamycin eliminates mouse Mallory-Denk bodies and blocks their proteasome inhibitor-mediated formation. | Hepatology (Baltimore, Md.) 20080601 |
| Multicenter trial of everolimus in pediatric renal transplant recipients: results at three year. | Pediatric transplantation 20080601 |
| Study comparing the double kissing (DK) crush with classical crush for the treatment of coronary bifurcation lesions: the DKCRUSH-1 Bifurcation Study with drug-eluting stents. | European journal of clinical investigation 20080601 |
| Impact of body mass index on the one-year clinical outcome of patients undergoing multivessel revascularization with sirolimus-eluting stents (from the Arterial Revascularization Therapies Study Part II). | The American journal of cardiology 20080601 |
| Comparison of effectiveness and safety of sirolimus-eluting stents versus bare-metal stents in patients with diabetes mellitus (from the Italian Multicenter Randomized DESSERT Study). | The American journal of cardiology 20080601 |
| Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt. | Journal of immunology (Baltimore, Md. : 1950) 20080601 |
| Drug reactions - new observations. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20080601 |
| Drug-eluting stent in saphenous vein graft lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601 |
| Platelet glycoprotein IIb/IIIa receptor inhibitors: is their future as bright as their past? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601 |
| Impact of platelet glycoprotein IIb/IIIa receptor inhibitors on outcomes of diabetic patients undergoing percutaneous coronary interventions using sirolimus-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080601 |
| Angiographic and clinical outcomes after sirolimus-eluting stent implantation to de novo ostial lesion of the right coronary artery: a retrospective study. | Circulation journal : official journal of the Japanese Circulation Society 20080601 |
| Sirolimus-eluting stents suppress neointimal formation irrespective of metallic allergy. | Circulation journal : official journal of the Japanese Circulation Society 20080601 |
| Concurrent administration of sirolimus and voriconazole: a pilot study assessing safety and approaches to appropriate management. | Pharmacotherapy 20080601 |
| Preliminary study of the use of drug-eluting stents in atherosclerotic renal artery stenoses 4 mm in diameter or smaller. | Journal of vascular and interventional radiology : JVIR 20080601 |
| Safety and efficacy of overlapping sirolimus-eluting versus paclitaxel-eluting stents. | American heart journal 20080601 |
| Akt-dependent regulation of NF-{kappa}B is controlled by mTOR and Raptor in association with IKK. | Genes & development 20080601 |
| Human melanoma cytolysis by combined inhibition of mammalian target of rapamycin and vascular endothelial growth factor/vascular endothelial growth factor receptor-2. | Cancer research 20080601 |
| Changes in tumor metabolism as readout for Mammalian target of rapamycin kinase inhibition by rapamycin in glioblastoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080601 |
| Combination strategy targeting the hypoxia inducible factor-1 alpha with mammalian target of rapamycin and histone deacetylase inhibitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080601 |
| Very late sirolimus-eluting stent displaced fracture in the mid-left anterior descending artery. | The Journal of invasive cardiology 20080601 |
| Midterm results of a sirolimus-eluting stent implanted for recurrent carotid in-stent restenosis. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20080601 |
| A novel bioengineered small-caliber vascular graft incorporating heparin and sirolimus: excellent 6-month patency. | The Journal of thoracic and cardiovascular surgery 20080601 |
| Failure of immunosuppressive drug levels to predict T-cell reactivity in pediatric transplant patients. | Journal of pediatric surgery 20080601 |
| Mammalian target of rapamycin inhibition as a therapeutic strategy in the management of urologic malignancies. | Molecular cancer therapeutics 20080601 |
| Intrinsically lower AKT, mammalian target of rapamycin, and hypoxia-inducible factor activity correlates with increased sensitivity to 2-deoxy-D-glucose under hypoxia in lung cancer cell lines. | Molecular cancer therapeutics 20080601 |
| Reduced risk of cytomegalovirus infection in solid organ transplant recipients treated with sirolimus: a pooled analysis of clinical trials. | Transplantation proceedings 20080601 |
| Observation of efficacy and safety of converting the calcineurin inhibitor to sirolimus in renal transplant recipients with chronic allograft nephropathy. | Transplantation proceedings 20080601 |
| The impact of conversion from mycophenolate mofetil to mycophenolate sodium among renal transplant recipients on a sirolimus-based regimen. | Transplantation proceedings 20080601 |
| Sirolimus-based immunosuppressive therapy in liver transplant recipient with tacrolimus-related chronic renal insufficiency. | Transplantation proceedings 20080601 |
| Demyelinating sensorimotor polyneuropathy associated with the use of sirolimus: a case report. | Transplantation proceedings 20080601 |
| Rapamycin, mycophenolate mofetil, methylprednisolone, and cytotoxic T-lymphocyte-associated antigen 4 immunoglobulin-based conditioning regimen to induce partial tolerance to hind limb allografts without cytoreductive conditioning. | Transplantation proceedings 20080601 |
| Antiproliferative and overadditive effects of rapamycin and FTY720 in pancreatic cancer cells in vitro. | Transplantation proceedings 20080601 |
| Case report: successful treatment of posttransplant lymphoproliferative disorder and quiescence of dermatomyositis with rituximab and sirolimus. | Transplantation proceedings 20080601 |
| Chylous ascites in a renal transplant recipient under sirolimus (rapamycin) treatment. | Transplantation proceedings 20080601 |
| Everolimus: an update on the mechanism of action, pharmacokinetics and recent clinical trials. | Expert opinion on drug metabolism & toxicology 20080601 |
| Short-term Efficacy of Topical Immunosuppressive Agents on the Survival of Cultivated Allo-Conjunctival Equivalents. | Korean journal of ophthalmology : KJO 20080601 |
| A retrospective study of conversion from tacrolimus-based to sirolimus-based immunosuppression in orthotopic liver transplant recipients. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20080601 |
| [Recent progress in the study on antitumor drugs targeting hypoxia-inducible factor-1]. | Yao xue xue bao = Acta pharmaceutica Sinica 20080601 |
| [Side branch occlusion rate at sites of overlapping sirolimus- or paclitaxel-eluting stents for treating long coronary lesions]. | Zhonghua xin xue guan bing za zhi 20080601 |
| Abnormal vasomotor function of porcine coronary arteries distal to sirolimus-eluting stents. | JACC. Cardiovascular interventions 20080601 |
| AMP-activated protein kinase is essential for survival in chronic hypoxia. | Biochemical and biophysical research communications 20080530 |
| Randomized trial of single-dose versus divided-dose rabbit anti-thymocyte globulin induction in renal transplantation: an interim report. | Transplantation 20080527 |
| Long-term outcome in patients treated with sirolimus-eluting stents in complex coronary artery lesions: 3-year results of the SCANDSTENT (Stenting Coronary Arteries in Non-Stress/Benestent Disease) trial. | Journal of the American College of Cardiology 20080527 |
| Aminoacyl-tRNA synthetase inhibitors as potent and synergistic immunosuppressants. | Journal of medicinal chemistry 20080522 |
| DTCA for PTCA--crossing the line in consumer health education? | The New England journal of medicine 20080522 |
| Response of a neuronal model of tuberous sclerosis to mammalian target of rapamycin (mTOR) inhibitors: effects on mTORC1 and Akt signaling lead to improved survival and function. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080521 |
| Mammalian target of rapamycin contributes to the acquired apoptotic resistance of human mesothelioma multicellular spheroids. | The Journal of biological chemistry 20080509 |
| Synthesis and drug release properties of poly(ethylene oxide) segmented polysulfone copolymers. | Journal of controlled release : official journal of the Controlled Release Society 20080508 |
| [Drug-eluting stent-associated thrombosis: clinical relevance of impaired vessel-wall healing]. | Postepy higieny i medycyny doswiadczalnej (Online) 20080508 |
| Study power in the SORT OUT II trial. | JAMA 20080507 |
| Epstein Barr virus induced lymphoma in a child with IPEX syndrome. | Pediatric blood & cancer 20080501 |
| Low dose rapamycin does not modulate p-glycoprotein function in acute myeloid leukaemia. | Leukemia research 20080501 |
| Neointimal coverage of bare-metal and sirolimus-eluting stents evaluated with optical coherence tomography. | Heart (British Cardiac Society) 20080501 |
| Prevention of atherosclerosis by the mTOR inhibitor everolimus in LDLR-/- mice despite severe hypercholesterolemia. | Atherosclerosis 20080501 |
| Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt. | Lung cancer (Amsterdam, Netherlands) 20080501 |
| Inhibitors of mammalian target of rapamycin downregulate MYCN protein expression and inhibit neuroblastoma growth in vitro and in vivo. | Oncogene 20080501 |
| Insulin-like growth factor-1 (IGF-1) and leucine activate pig myogenic satellite cells through mammalian target of rapamycin (mTOR) pathway. | Molecular reproduction and development 20080501 |
| Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma. | European urology 20080501 |
| Effects of stem cell therapy with G-CSF on coronary artery after drug-eluting stent implantation in patients with acute myocardial infarction. | Heart (British Cardiac Society) 20080501 |
| Accuracy and variability of equations to estimate glomerular filtration rates in renal transplant patients receiving sirolimus and/or calcineurin inhibitor immunosuppression. | Transplant international : official journal of the European Society for Organ Transplantation 20080501 |
| Nitric oxide mediates NMDA-induced persistent inhibition of protein synthesis through dephosphorylation of eukaryotic initiation factor 4E-binding protein 1 and eukaryotic initiation factor 4G proteolysis. | The Biochemical journal 20080501 |
| Autophagy plays a protective role during zVAD-induced necrotic cell death. | Autophagy 20080501 |
| Combined treatment with triptolide and rapamycin prolongs graft survival in a mouse model of cardiac transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20080501 |
| Induction of transplantation tolerance by combining non-myeloablative conditioning with delivery of alloantigen by T cells. | Clinical immunology (Orlando, Fla.) 20080501 |
| Intramural delivery of rapamycin with alphavbeta3-targeted paramagnetic nanoparticles inhibits stenosis after balloon injury. | Arteriosclerosis, thrombosis, and vascular biology 20080501 |
| Sirolimus-based immunosuppression following liver transplantation for hepatocellular carcinoma. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080501 |
| Rapamycin suppresses TLR4-triggered IL-6 and PGE(2) production of colon cancer cells by inhibiting TLR4 expression and NF-kappaB activation. | Molecular immunology 20080501 |
| Renal cell carcinoma. | Current opinion in oncology 20080501 |
| Novel targets for Huntington's disease in an mTOR-independent autophagy pathway. | Nature chemical biology 20080501 |
| Impact of rapamycin on liver regeneration. | Virchows Archiv : an international journal of pathology 20080501 |
| Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis. | Current opinion in clinical nutrition and metabolic care 20080501 |
| Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080501 |
| Incidence of PTLD in pediatric renal transplant recipients receiving basiliximab, calcineurin inhibitor, sirolimus and steroids. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080501 |
| Amelioration of protein misfolding disease by rapamycin: translation or autophagy? | Autophagy 20080501 |
| Nanomedicine captures cardiovascular disease. | Arteriosclerosis, thrombosis, and vascular biology 20080501 |
| Cutting edge: Foxp3-mediated induction of pim 2 allows human T regulatory cells to preferentially expand in rapamycin. | Journal of immunology (Baltimore, Md. : 1950) 20080501 |
| Constitutive activation of p70 S6 kinase is associated with intrinsic resistance to cisplatin. | International journal of oncology 20080501 |
| Islet transplantation in patients with autoimmune diabetes induces homeostatic cytokines that expand autoreactive memory T cells. | The Journal of clinical investigation 20080501 |
| Sirolimus conversion for renal preservation in liver transplantation: not so fast. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080501 |
| Sirolimus in liver transplant recipients with renal dysfunction offers no advantage over low-dose calcineurin inhibitor regimens. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20080501 |
| Overproduction of non-translatable mRNA silences. The transcription of Ty1 retrotransposons in S. cerevisiae via functional inactivation of the nuclear cap-binding complex and subsequent hyperstimulation of the TORC1 pathway. | Yeast (Chichester, England) 20080501 |
| Outcomes after sirolimus- and paclitaxel-eluting stent implantation in patients with insulin-treated diabetes mellitus. | The American journal of cardiology 20080501 |
| Effect of rapamycin therapy on coronary artery physiology early after cardiac transplantation. | American heart journal 20080501 |
| Sirolimus for lymphangioleiomyomatosis lesions. | The New England journal of medicine 20080501 |
| Loss of tuberous sclerosis complex-2 function and activation of mammalian target of rapamycin signaling in endometrial carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080501 |
| A phase 2 clinical trial of deforolimus (AP23573, MK-8669), a novel mammalian target of rapamycin inhibitor, in patients with relapsed or refractory hematologic malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080501 |
| Coronary aneurysm formation in a patient early after everolimus-eluting stent implantation. | The Journal of invasive cardiology 20080501 |
| [Coronary artery bypass grafting for simultaneous subacute stent thrombosis after sirolimus-eluting stent implantation]. | Kyobu geka. The Japanese journal of thoracic surgery 20080501 |
| Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors. | Molecular cancer therapeutics 20080501 |
| Kaposi's sarcoma resolves after sirolimus therapy in a patient with pemphigus vulgaris. | Archives of dermatology 20080501 |
| Classic Mediterranean Kaposi's sarcoma regression with sirolimus treatment. | Archives of dermatology 20080501 |
| Molecular target therapies in endometrial cancer: from the basic research to the clinic. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20080501 |
| Polycystic kidney disease: will it become treatable? | Polskie Archiwum Medycyny Wewnetrznej 20080501 |
| [Use of Sirolimus in five pediatric patients undergoing solid organ transplantation]. | Revista medica de Chile 20080501 |
| EXCELLA First-in-Man (FIM) study: safety and efficacy of novolimus-eluting stent in de novo coronary lesions. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501 |
| Biodegradable-polymer-based, sirolimus-eluting Supralimus stent: 6-month angiographic and 30-month clinical follow-up results from the series I prospective study. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501 |
| Novel drug eluting stent system for customised treatment of coronary lesions: CUSTOM I feasibility trial 24 month results. | EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology 20080501 |
| Kidney transplant histology after one year of continuous therapy with sirolimus compared with tacrolimus. | Transplantation 20080427 |
| The incidence and clinical impact of stent strut fractures developed after drug-eluting stent implantation. | International journal of cardiology 20080425 |
| Safety and efficacy of the CYPHER Select Sirolimus-eluting stent in the 'Real World'--clinical and angiographic results from the China CYPHER Select registry. | International journal of cardiology 20080425 |
| Comparison of an everolimus-eluting stent and a paclitaxel-eluting stent in patients with coronary artery disease: a randomized trial. | JAMA 20080423 |
| Next-generation drug-eluting stents: a spirited step forward or more of the same. | JAMA 20080423 |
| Four-year clinical follow-up of the rapamycin-eluting stent evaluated at Rotterdam Cardiology Hospital registry. | The American journal of cardiology 20080415 |
| Carcinoma 'en Cuirasse' from cutaneous squamous cell carcinoma in a renal transplant patient. | Transplantation 20080415 |
| Bile acid exposure up-regulates tuberous sclerosis complex 1/mammalian target of rapamycin pathway in Barrett's-associated esophageal adenocarcinoma. | Cancer research 20080415 |
| A new pharmacologic action of CCI-779 involves FKBP12-independent inhibition of mTOR kinase activity and profound repression of global protein synthesis. | Cancer research 20080415 |
| Tor pathway control of the nitrogen-responsive DAL5 gene bifurcates at the level of Gln3 and Gat1 regulation in Saccharomyces cerevisiae. | The Journal of biological chemistry 20080404 |
| The PtdIns(4,5)P2 ligand itself influences the localization of PKCalpha in the plasma membrane of intact living cells. | Journal of molecular biology 20080404 |
| Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program. | Pediatric blood & cancer 20080401 |
| Quantitative spatial distribution of sirolimus and polymers in drug-eluting stents using confocal Raman microscopy. | Journal of biomedical materials research. Part A 20080401 |
| mTOR is activated in the majority of malignant melanomas. | The Journal of investigative dermatology 20080401 |
| Drug-eluting stents in renal artery stenosis. | European radiology 20080401 |
| GLN3 encodes a global regulator of nitrogen metabolism and virulence of C. albicans. | Fungal genetics and biology : FG & B 20080401 |
| Assessment of potential relationship between wall shear stress and arterial wall response after bare metal stent and sirolimus-eluting stent implantation in patients with diabetes mellitus. | The international journal of cardiovascular imaging 20080401 |
| [Renal cell carcinoma and antiangiogenic therapies]. | Presse medicale (Paris, France : 1983) 20080401 |
| Evaluation of the dedicated Frontier coronary bifurcation stent: A matched pair analysis with drug-eluting and bare metal stents. | Clinical research in cardiology : official journal of the German Cardiac Society 20080401 |
| Sirolimus-eluting stents in the treatment of chronic total coronary occlusions: results from the prospective multi-center German Cypher Stent Registry. | Clinical research in cardiology : official journal of the German Cardiac Society 20080401 |
| Rapamycin modulates the eNOS vs. shear stress relationship. | Cardiovascular research 20080401 |
| mTOR inhibition by rapamycin prevents beta-cell adaptation to hyperglycemia and exacerbates the metabolic state in type 2 diabetes. | Diabetes 20080401 |
| The itinerary of autophagosomes: from peripheral formation to kiss-and-run fusion with lysosomes. | Traffic (Copenhagen, Denmark) 20080401 |
| Modulation of Na+-Ca2+ exchanger expression by immunosuppressive drugs is isoform-specific. | Molecular pharmacology 20080401 |
| Rapamycin inhibits polyglutamine aggregation independently of autophagy by reducing protein synthesis. | Molecular pharmacology 20080401 |
| Roles of autophagy and mTOR signaling in neuronal differentiation of mouse neuroblastoma cells. | Cellular signalling 20080401 |
| Hypoxia stimulus: An adaptive immune response during dendritic cell maturation. | Kidney international 20080401 |
| Strategies to induce marked prolongation of secondary skin allograft survival in alloantigen-primed mice. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401 |
| Development of proteinuria after switch to sirolimus-based immunosuppression in long-term cardiac transplant patients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401 |
| CD4+ CD25+ FOXP3+ regulatory T cells increase de novo in kidney transplant patients after immunodepletion with Campath-1H. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080401 |
| Long-term effects of rapamycin treatment on insulin mediated phosphorylation of Akt/PKB and glycogen synthase activity. | Experimental cell research 20080401 |
| Trends in adult post-kidney transplant immunosuppressive use in Australia, 1991-2005. | Nephrology (Carlton, Vic.) 20080401 |
| Long-term clinical outcomes after sirolimus-eluting stent implantation for treatment of restenosis within bare-metal versus drug-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401 |
| Identifying optimal biologic doses of everolimus (RAD001) in patients with cancer based on the modeling of preclinical and clinical pharmacokinetic and pharmacodynamic data. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401 |
| Dose- and schedule-dependent inhibition of the mammalian target of rapamycin pathway with everolimus: a phase I tumor pharmacodynamic study in patients with advanced solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401 |
| Phase I pharmacokinetic and pharmacodynamic study of the oral mammalian target of rapamycin inhibitor everolimus in patients with advanced solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080401 |
| Evaluation and management of steroid-unresponsive nephrotic syndrome. | Current opinion in pediatrics 20080401 |
| Very very late thrombosis of a sirolimus-eluting stent: does suboptimal stent expansion take its toll even after three years? | Journal of cardiovascular medicine (Hagerstown, Md.) 20080401 |
| Simultaneous subacute coronary drug-eluting stent thrombosis in two different vessels of a patient with factor V Leiden mutation. | Journal of cardiovascular medicine (Hagerstown, Md.) 20080401 |
| Short-period hypoxia increases mouse embryonic stem cell proliferation through cooperation of arachidonic acid and PI3K/Akt signalling pathways. | Cell proliferation 20080401 |
| Acute allograft rejection and immunosuppression: influence on endogenous melatonin secretion. | Journal of pineal research 20080401 |
| Temsirolimus downregulates p21 without altering cyclin D1 expression and induces autophagy and synergizes with vorinostat in mantle cell lymphoma. | Experimental hematology 20080401 |
| Activation and function of the mTORC1 pathway in mast cells. | Journal of immunology (Baltimore, Md. : 1950) 20080401 |
| Antiproliferative effect of rapamycin on human T-cell leukemia cell line Jurkat by cell cycle arrest and telomerase inhibition. | Acta pharmacologica Sinica 20080401 |
| Long-term (>3 Years) outcome and predictors of clinical events after insertion of sirolimus-eluting stent in one or more native coronary arteries (from the Israeli arm of the e-Cypher registry). | The American journal of cardiology 20080401 |
| Rapamycin and tuberous sclerosis complex: from Easter Island to epilepsy. | Annals of neurology 20080401 |
| Treatment of drug-eluting stent restenosis: a sandwich may not be the best combo. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401 |
| Stent fracture, an incidental finding or a significant marker of clinical in-stent restenosis? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401 |
| Stent strut fracture: seeing is believing. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401 |
| Survival advantage in Medicare patients receiving drug-eluting stents compared with bare metal stents: real or artefactual? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401 |
| DES editorial. Is there a survival benefit? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080401 |
| Effect of lumen narrowing within sirolimus-eluting stents on proximal and distal vessel segments. | Circulation journal : official journal of the Japanese Circulation Society 20080401 |
| Pharmacokinetics of mycophenolate mofetil and sirolimus in children. | Therapeutic drug monitoring 20080401 |
| Role of pharmacogenetics of immunosuppressive drugs in organ transplantation. | Therapeutic drug monitoring 20080401 |
| Toxicodynamic therapeutic drug monitoring of immunosuppressants: promises, reality, and challenges. | Therapeutic drug monitoring 20080401 |
| The effect of drug-eluting stents on intermediate angiographic and clinical outcomes in diabetic patients: insights from randomized clinical trials. | American heart journal 20080401 |
| P70 S6 kinase negatively regulates fibroblast growth factor 2-stimulated interleukin-6 synthesis in osteoblasts: function at a point downstream from protein kinase C. | The Journal of endocrinology 20080401 |
| Effects of cyclosporine, tacrolimus and sirolimus on vascular changes related to immune response. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080401 |
| Regression of pulmonary lymphangioleiomyomatosis (PLAM)-associated retroperitoneal angiomyolipoma post-lung transplantation with rapamycin treatment. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080401 |
| Mammalian target of rapamycin and S6 kinase 1 positively regulate 6-thioguanine-induced autophagy. | Cancer research 20080401 |
| Rapamycin prevents epilepsy in a mouse model of tuberous sclerosis complex. | Annals of neurology 20080401 |
| Rapid activation of Akt2 is sufficient to stimulate GLUT4 translocation in 3T3-L1 adipocytes. | Cell metabolism 20080401 |
| Treatment options for metastatic renal cell carcinoma: a review. | The Canadian journal of urology 20080401 |
| Rapamycin prevents the development of nephritis in lupus-prone NZB/W F1 mice. | Lupus 20080401 |
| Preclinical evidences suggest new treatment options for endocrine disorders: Pasireotide (SOM230) and Everolimus (RAD001). | Annales d'endocrinologie 20080401 |
| Conversion therapy to everolimus in renal transplant recipients: results after one year. | Transplantation proceedings 20080401 |
| Drug-eluting stents: present and future. | Cardiovascular & hematological agents in medicinal chemistry 20080401 |
| Polypyrimidine tract-binding protein is involved in regulation of albumin synthesis in response to food intake. | Journal of nutritional science and vitaminology 20080401 |
| Results of provisional stenting with a Sirolimus-eluting stent for bifurcation lesion: multicenter study in Japan. | Journal of cardiology 20080401 |
| [Coronary angioplasty in the real world: the RESTEM registry. Outcome of patients treated with sirolimus-eluting stents]. | Giornale italiano di cardiologia (2006) 20080401 |
| mToR inhibitors-induced proteinuria: mechanisms, significance, and management. | Transplantation reviews (Orlando, Fla.) 20080401 |
| Drug-eluting versus bare-metal stents in the treatment of patients with ST-segment elevation myocardial infarction. | JACC. Cardiovascular interventions 20080401 |
| Should we routinely use drug-eluting stents for acute myocardial infarction? Let's wait and see. | JACC. Cardiovascular interventions 20080401 |
| Stent malapposition after sirolimus-eluting and bare-metal stent implantation in patients with ST-segment elevation myocardial infarction: acute and 9-month intravascular ultrasound results of the MISSION! intervention study. | JACC. Cardiovascular interventions 20080401 |
| Drug essentials mTOR inhibitors. | Oncology (Williston Park, N.Y.) 20080401 |
| Human immunodeficiency virus type-1 infection inhibits autophagy. | AIDS (London, England) 20080330 |
| Intravascular ultrasound findings in patients with restenosis of sirolimus- and paclitaxel-eluting stents. | International journal of cardiology 20080328 |
| Impact of significant chronic kidney disease on long-term clinical outcomes after drug-eluting stent versus bare metal stent implantation. | International journal of cardiology 20080328 |
| Impact of immunosuppressive drugs on CD4+CD25+FOXP3+ regulatory T cells: does in vitro evidence translate to the clinical setting? | Transplantation 20080327 |
| Multicenter, randomized study of the use of everolimus with tacrolimus after renal transplantation demonstrates its effectiveness. | Transplantation 20080327 |
| Asymmetric dimethylarginine and cardiac allograft vasculopathy progression: modulation by sirolimus. | Transplantation 20080327 |
| Novel immunosuppression: R348, a JAK3- and Syk-inhibitor attenuates acute cardiac allograft rejection. | Transplantation 20080327 |
| Overview of the 2007 Food and Drug Administration Circulatory System Devices Panel meeting on the endeavor zotarolimus-eluting coronary stent. | Circulation 20080325 |
| Sirolimus-eluting cobalt-chromium stents: two-year clinical results from first-in-man study on the Firebird 2 stent. | Chinese medical journal 20080320 |
| Neointimal coverage of sirolimus-eluting stents 6 months and 12 months after implantation: evaluation by optical coherence tomography. | Chinese medical journal 20080320 |
| Crush stenting in treating coronary bifurcate lesions: paclitaxel eluting stents versus sirolimus eluting stents. | Chinese medical journal 20080320 |
| Inflammatory response, drug-eluting stent and restenosis. | Chinese medical journal 20080320 |
| Delivery of rapamycin by PLGA nanoparticles enhances its suppressive activity on dendritic cells. | Journal of biomedical materials research. Part A 20080315 |
| Effectiveness of drug-eluting stent implantation for patients with unprotected left main coronary artery stenosis. | The American journal of cardiology 20080315 |
| Mammalian target of rapamycin repression by 3,3'-diindolylmethane inhibits invasion and angiogenesis in platelet-derived growth factor-D-overexpressing PC3 cells. | Cancer research 20080315 |
| Biodegradable drug-eluting stents: promises and pitfalls. | Lancet (London, England) 20080315 |
| Decision time for pancreatic islet-cell transplantation. | Lancet (London, England) 20080315 |
| A bioabsorbable everolimus-eluting coronary stent system for patients with single de-novo coronary artery lesions (ABSORB): a prospective open-label trial. | Lancet (London, England) 20080315 |
| Loss of the tuberous sclerosis complex tumor suppressors triggers the unfolded protein response to regulate insulin signaling and apoptosis. | Molecular cell 20080314 |
| Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs. | British journal of cancer 20080311 |
| Drug-eluting stent thrombosis: results from the multicenter Spanish registry ESTROFA (Estudio ESpañol sobre TROmbosis de stents FArmacoactivos). | Journal of the American College of Cardiology 20080311 |
| Long-term follow-up evaluation after sirolimus-eluting stent implantation by optical coherence tomography: do uncovered struts persist? | Journal of the American College of Cardiology 20080304 |
| Chemical imaging of drug eluting coatings: combining surface analysis and confocal Raman microscopy. | Journal of controlled release : official journal of the Controlled Release Society 20080303 |
| Impact of late incomplete stent apposition after sirolimus-eluting stent implantation on 4-year clinical events: intravascular ultrasound analysis from the multicentre, randomised, RAVEL, E-SIRIUS and SIRIUS trials. | Heart (British Cardiac Society) 20080301 |
| Subversion of cellular autophagy by Anaplasma phagocytophilum. | Cellular microbiology 20080301 |
| Components of the Vid30c are needed for the rapamycin-induced degradation of the high-affinity hexose transporter Hxt7p in Saccharomyces cerevisiae. | FEMS yeast research 20080301 |
| On the participation of mTOR in recognition memory. | Neurobiology of learning and memory 20080301 |
| Mitogen-stimulated and rapamycin-sensitive glucose transporter 12 targeting and functional glucose transport in renal epithelial cells. | Endocrinology 20080301 |
| Sirolimus ameliorates the enhanced expression of metalloproteinases in a rat model of autosomal dominant polycystic kidney disease. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080301 |
| Immunosuppression and tumor development in organ transplant recipients: the emerging dualistic role of rapamycin. | Transplant international : official journal of the European Society for Organ Transplantation 20080301 |
| Synergistic effect of mTOR inhibitor rapamycin and fluorouracil in inducing apoptosis and cell senescence in hepatocarcinoma cells. | Cancer biology & therapy 20080301 |
| Targeting 14-3-3 sensitizes native and mutant BCR-ABL to inhibition with U0126, rapamycin and Bcl-2 inhibitor GX15-070. | Leukemia 20080301 |
| Interferon beta augments tuberous sclerosis complex 2 (TSC2)-dependent inhibition of TSC2-null ELT3 and human lymphangioleiomyomatosis-derived cell proliferation. | Molecular pharmacology 20080301 |
| Phospho-S6 ribosomal protein: a potential new predictive sarcoma marker for targeted mTOR therapy. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20080301 |
| Synergic antiproliferative and antiangiogenic effects of EGFR and mTor inhibitors on pancreatic cancer cells. | Biochemical pharmacology 20080301 |
| Sirolimus reduces polycystic liver volume in ADPKD patients. | Journal of the American Society of Nephrology : JASN 20080301 |
| Pharmacokinetics of sirolimus (rapamycin) in subjects with severe hepatic impairment. | Journal of clinical pharmacology 20080301 |
| Delta-24-RGD in combination with RAD001 induces enhanced anti-glioma effect via autophagic cell death. | Molecular therapy : the journal of the American Society of Gene Therapy 20080301 |
| Human herpesvirus-8 (HHV-8)-associated primary effusion lymphoma in two renal transplant recipients receiving rapamycin. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20080301 |
| mTOR signaling contributes to chondrocyte differentiation. | Developmental dynamics : an official publication of the American Association of Anatomists 20080301 |
| STAT5-signaling cytokines regulate the expression of FOXP3 in CD4+CD25+ regulatory T cells and CD4+CD25- effector T cells. | International immunology 20080301 |
| Two-year clinical outcome after implantation of sirolimus-eluting and paclitaxel-eluting stents in diabetic patients. | European heart journal 20080301 |
| Late incomplete stent apposition after drug-eluting stent implantation: a true risk factor or 'an innocent bystander'? | Heart (British Cardiac Society) 20080301 |
| Luminal narrowing after sirolimus-eluting stent implantation for in-stent restenosis using intravascular ultrasound. | American heart journal 20080301 |
| Immediate and long-term outcomes of drug-eluting stent implantation for unprotected left main coronary artery disease: comparison with bare-metal stent implantation. | American heart journal 20080301 |
| Biological action of rapamycin in renal transplantation. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20080301 |
| Clinical safety of drug-eluting stents in the Korea acute myocardial infarction registry. | Circulation journal : official journal of the Japanese Circulation Society 20080301 |
| Inflammation and delayed endothelization with overlapping drug-eluting stents in a porcine model of in-stent restenosis. | Circulation journal : official journal of the Japanese Circulation Society 20080301 |
| Higher incidence and serum levels of minor cardiac biomarker elevation in sirolimus-eluting stent (Cypher) than bare metal stent implantations. | Coronary artery disease 20080301 |
| Differential outcomes after sirolimus-eluting stent implantation: comparing on-label versus off-label patients in the 'real world'. | Coronary artery disease 20080301 |
| Exploiting the mammalian target of rapamycin pathway in hematologic malignancies. | Current opinion in hematology 20080301 |
| Vascular endothelial growth factor protein levels and gene expression in peripheral monocytes after stenting: a randomized comparative study of sirolimus: eluting and bare metal stents. | European heart journal 20080301 |
| Unprotected left main disease managed with drug-eluting stents: long-term outcome of 100 patients with increased surgical risk. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301 |
| Outcomes of nonagenarians who undergo percutaneous coronary intervention with drug-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301 |
| Percutaneous coronary intervention in nonagenarians: age before beauty? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301 |
| Stenting unprotected left main: the outcome is not always favorable. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080301 |
| Antitumor activity of rapamycin and octreotide as single agents or in combination in neuroendocrine tumors. | Endocrine-related cancer 20080301 |
| Temsirolimus, an inhibitor of mammalian target of rapamycin. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080301 |
| Preclinical cancer therapy in a mouse model of neurofibromatosis-1 optic glioma. | Cancer research 20080301 |
| Damage to polymer of undelivered sirolimus-eluting stents. | The Journal of invasive cardiology 20080301 |
| Intervention of stenosed right coronary artery and anomalous left main coronary artery: single main coronary trunk. | The Journal of invasive cardiology 20080301 |
| FK506 binding protein mediates glioma cell growth and sensitivity to rapamycin treatment by regulating NF-kappaB signaling pathway. | Neoplasia (New York, N.Y.) 20080301 |
| A new trick for an old drug: mTOR inhibitor rapamycin augments the effect of fluorouracil on hepatocellular carcinoma by inducing cell senescence. | Cancer biology & therapy 20080301 |
| Pharmacological characterization of purified recombinant mTOR FRB-kinase domain using fluorescence-based assays. | Journal of biomolecular screening 20080301 |
| [Rapamycin combined with donor bone marrow-derived immature dendritic cells induces mouse skin allograft tolerance]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080301 |
| Therapeutic interventions for autosomal dominant polycystic kidney disease. | Nephrology news & issues 20080301 |
| Rapamycin impairs beta-cell proliferation in vivo. | Transplantation proceedings 20080301 |
| Influence of rapamycin on rat macrophage viability and chemotaxis toward allogenic pancreatic islet supernates. | Transplantation proceedings 20080301 |
| Can we maintain immunosuppression avoiding nephrotoxic agents in pancreas transplantation? | Transplantation proceedings 20080301 |
| Effects of drug-eluting stents on systemic inflammatory response in patients with unstable angina pectoris undergoing percutaneous coronary intervention. | Heart and vessels 20080301 |
| Impact of sirolimus treatment in kidney allograft recipients with prolonged cold ischemia times: 5-year outcomes. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20080301 |
| Fourteen month follow-up angioscopic findings of a sirolimus-eluting stent implanted in a 15-year-old saphenous vein graft. | International heart journal 20080301 |
| Successful percutaneous treatment of an intraprocedural left main stent thrombosis with the support of an automatic mechanical chest compression device. | International journal of cardiology 20080227 |
| Poor tolerance of sirolimus in a steroid avoidance regimen for renal transplantation. | Transplantation 20080227 |
| Pericardial effusion coincident with sirolimus therapy: a review of Wyeth's safety database. | Transplantation 20080227 |
| Safety and effectiveness of sirolimus-eluting stent implantation for in-stent restenosis of the unprotected left main coronary artery. | International journal of cardiology 20080220 |
| Two-year clinical outcomes with drug-eluting stents for diabetic patients with de novo coronary lesions: results from a real-world multicenter registry. | Circulation 20080219 |
| Safe use of raltegravir and sirolimus in an HIV-infected patient with renal impairment after orthotopic liver transplantation. | AIDS (London, England) 20080219 |
| [Angiogenesis inhibitors for the systemic treatment of metastatic renal cell carcinoma: sunitinib, sorafenib, bevacizumab and temsirolimus]. | Nederlands tijdschrift voor geneeskunde 20080216 |
| Late target lesion revascularization after implantation of sirolimus-eluting stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215 |
| IL-2- and IL-15-induced activation of the rapamycin-sensitive mTORC1 pathway in malignant CD4+ T lymphocytes. | Blood 20080215 |
| A critical role for Lyn in acute myeloid leukemia. | Blood 20080215 |
| A retroinhibition approach reveals a tumor cell-autonomous response to rapamycin in head and neck cancer. | Cancer research 20080215 |
| Suppression of Peutz-Jeghers polyposis by targeting mammalian target of rapamycin signaling. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080215 |
| Comparison of a polymer-free rapamycin-eluting stent (YUKON) with a polymer-based paclitaxel-eluting stent (TAXUS) in real-world coronary artery lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215 |
| Late target lesion revascularization following drug-eluting stents - looking back and forward to success. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215 |
| Drug for a while, polymer for life: Is it a good solution? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215 |
| Drug-eluting stenting of unprotected left main coronary artery stenosis in patients with orthotopic heart transplantation: Initial clinical experience. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20080215 |
| Prospective comparison of the use of sirolimus and cyclosporine in recipients of a kidney from an expanded criteria donor. | Transplantation 20080215 |
| Prognostic value of the modified American College of Cardiology/American Heart Association lesion morphology classification for clinical outcome after sirolimus-eluting stent placement (results of the prospective multicenter German Cypher Registry). | The American journal of cardiology 20080215 |
| Defective TGF-beta signaling sensitizes human cancer cells to rapamycin. | Oncogene 20080214 |
| Regulation of cyclin D1 expression by mTORC1 signaling requires eukaryotic initiation factor 4E-binding protein 1. | Oncogene 20080214 |
| Preparation of rapamycin-loaded chitosan/PLA nanoparticles for immunosuppression in corneal transplantation. | International journal of pharmaceutics 20080212 |
| 'Off-label' stent therapy 2-year comparison of drug-eluting versus bare-metal stents. | Journal of the American College of Cardiology 20080212 |
| Sirolimus-eluting stents versus bare-metal stents in patients with ST-segment elevation myocardial infarction: 9-month angiographic and intravascular ultrasound results and 12-month clinical outcome results from the MISSION! Intervention Study. | Journal of the American College of Cardiology 20080212 |
| Development of Kaposi's sarcoma under sirolimus-based immunosuppression and successful treatment with imiquimod. | Transplant infectious disease : an official journal of the Transplantation Society 20080201 |
| Rhodococcus lung abscess complicating kidney transplantation: successful management by combination antibiotic therapy. | Transplant infectious disease : an official journal of the Transplantation Society 20080201 |
| Rapamycin inhibits osteoblast proliferation and differentiation in MC3T3-E1 cells and primary mouse bone marrow stromal cells. | Journal of cellular biochemistry 20080201 |
| Angiographic and 3D intravascular ultrasound assessment of overlapping bare metal stent and three different formulations of drug-eluting stents in patients with diabetes mellitus. | The international journal of cardiovascular imaging 20080201 |
| Pulmonary lymphangioleiomyomatosis (LAM): progress and current challenges. | Journal of cellular biochemistry 20080201 |
| Role of ICOS pathway in autoimmune and alloimmune responses in NOD mice. | Clinical immunology (Orlando, Fla.) 20080201 |
| A randomized exploratory trial of steroid avoidance in renal transplant patients treated with everolimus and low-dose cyclosporine. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080201 |
| Mechanical stimuli of skeletal muscle: implications on mTOR/p70s6k and protein synthesis. | European journal of applied physiology 20080201 |
| Activation or inactivation of cardiac Akt/mTOR signaling diverges physiological from pathological hypertrophy. | Journal of cellular physiology 20080201 |
| Dasatinib, a small-molecule protein tyrosine kinase inhibitor, inhibits T-cell activation and proliferation. | Blood 20080201 |
| Renal cortex neuronal nitric oxide synthase in response to rapamycin in kidney transplantation. | Nitric oxide : biology and chemistry 20080201 |
| Amplification at 7q22 targets cyclin-dependent kinase 6 in T-cell lymphoma. | Leukemia 20080201 |
| Induction of autophagy promotes fusion of multivesicular bodies with autophagic vacuoles in k562 cells. | Traffic (Copenhagen, Denmark) 20080201 |
| Conversion to sirolimus for chronic allograft dysfunction: long-term results confirm predictive value of proteinuria. | Transplant international : official journal of the European Society for Organ Transplantation 20080201 |
| Effect of calcineurin inhibitors on posaconazole blood levels as measured by the MVista microbiological assay. | Antimicrobial agents and chemotherapy 20080201 |
| EMAP-II downregulation contributes to the beneficial effects of rapamycin after vascular injury. | Cardiovascular research 20080201 |
| mTORC1 signaling can regulate growth factor activation of p44/42 mitogen-activated protein kinases through protein phosphatase 2A. | The Journal of biological chemistry 20080201 |
| Sirolimus eluting stent (Cypher) in patients with diabetes mellitus: results from the German Cypher Stent Registry. | Clinical research in cardiology : official journal of the German Cardiac Society 20080201 |
| Coronary in-stent restenosis in diabetic patients after implantation of sirolimus or paclitaxel drug-eluting coronary stents. | Diabetes & metabolism 20080201 |
| Reduced positive affect (anhedonia) predicts major clinical events following implantation of coronary-artery stents. | Journal of internal medicine 20080201 |
| The effects of sirolimus on wound healing in dermatologic surgery. | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20080201 |
| Low-dose mTOR inhibition by rapamycin attenuates progression in anti-thy1-induced chronic glomerulosclerosis of the rat. | American journal of physiology. Renal physiology 20080201 |
| Rapamycin-conditioned, alloantigen-pulsed dendritic cells promote indefinite survival of vascularized skin allografts in association with T regulatory cell expansion. | Transplant immunology 20080201 |
| The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. | The Journal of clinical investigation 20080201 |
| Three-dimensional compositional analysis of drug eluting stent coatings using cluster secondary ion mass spectrometry. | Analytical chemistry 20080201 |
| Lentiviral vectors mediate nonimmunosuppressive rapamycin analog-induced production of secreted therapeutic factors in the brain: regulation at the level of transcription and exocytosis. | Human gene therapy 20080201 |
| Transplantation: it may take two to tango and to treat. | Immunology and cell biology 20080201 |
| Upregulation of tissue factor expression and thrombogenic activity in human aortic smooth muscle cells by irradiation, rapamycin and paclitaxel. | International immunopharmacology 20080201 |
| Sicilian DES Registry: prospective in-hospital and 9-month clinical and angiographic follow-up in selected high restenosis risk patients. | Journal of cardiovascular medicine (Hagerstown, Md.) 20080201 |
| Recurrent restenosis after implantation of sirolimus-eluting stents in aorto-ostial lesions: successful treatment with polytetrafluoroethylene-covered stents. | Journal of cardiovascular medicine (Hagerstown, Md.) 20080201 |
| Sirolimus-based triple immunosupression with antithymocyte globulin induction in expanded criteria donor kidney transplantation. | Nephrology (Carlton, Vic.) 20080201 |
| Antiproliferative and proapoptotic effects of rapamycin and celecoxib in malignant melanoma cell lines. | Oncology reports 20080201 |
| Sirolimus associated pneumonitis after nonmyeloablative peripheral blood stem cell transplant for sickle cell disease. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20080201 |
| Incidence of premature discontinuation of antiplatelet therapy after sirolimus-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20080201 |
| Everolimus exposure in cardiac transplant recipients is influenced by concomitant calcineurin inhibitor. | Therapeutic drug monitoring 20080201 |
| Inhibition of the mammalian target of rapamycin (mTOR) in a case of refractory primary cutaneous anaplastic large cell lymphoma. | Leukemia & lymphoma 20080201 |
| Effects of rapamycin in liver transplantation. | Hepatobiliary & pancreatic diseases international : HBPD INT 20080201 |
| Increased expression of the glioma-associated antigen ARF4L after loss of the tumor suppressor PTEN. Laboratory investigation. | Journal of neurosurgery 20080201 |
| Antiangiogenic therapy with mammalian target of rapamycin inhibitor RAD001 (Everolimus) increases radiosensitivity in solid cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080201 |
| Lymphangioleiomyomatosis: a clinical update. | Chest 20080201 |
| Pulmonary complications of novel antineoplastic agents for solid tumors. | Chest 20080201 |
| Multidisciplinary insights on clinical guidance for the use of proliferation signal inhibitors in heart transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080201 |
| Cyclosporine reduction in the presence of everolimus: 3-month data from a Canadian pilot study of maintenance cardiac allograft recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20080201 |
| Expression of signaling mediators downstream of EGF-receptor predict sensitivity to small molecule inhibitors directed against the EGF-receptor pathway. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080201 |
| The potential role of mTOR inhibitors in non-small cell lung cancer. | The oncologist 20080201 |
| Effects of the mTOR inhibitor sirolimus in patients with hepatocellular and cholangiocellular cancer. | International journal of clinical oncology 20080201 |
| Drug-eluting stents: a review of current evidence on clinical effectiveness and late complications. | Scottish medical journal 20080201 |
| Towards defining the role of drug eluting stents. | Minerva cardioangiologica 20080201 |
| Sirolimus, Tacrolimus and Zotarolimus eluting stents to treat bifurcated lesions: a 7-month clinical outcome comparison. | Minerva cardioangiologica 20080201 |
| Percutaneous coronary intervention with everolimus-eluting stents (Xience V): systematic review and direct-indirect comparison meta-analyses with paclitaxel-eluting stents (Taxus) and sirolimus-eluting stents (Cypher). | Minerva cardioangiologica 20080201 |
| Future stent drug delivery systems. | Minerva cardioangiologica 20080201 |
| Primary and mid-term outcome of sirolimus-eluting stent implantation with angiographic guidance alone. | Journal of cardiology 20080201 |
| Medial necrosis due to sirolimus-eluting stent implantation in human coronary artery. | Journal of cardiology 20080201 |
| Late giant coronary aneurysm associated with a fracture of sirolimus eluting stent: a case report. | Journal of cardiology 20080201 |
| Next-generation drug-eluting stents in coronary artery disease: focus on everolimus-eluting stent (Xience V). | Vascular health and risk management 20080201 |
| Advances in immunosuppression for pancreas transplantation. | Current opinion in organ transplantation 20080201 |
| [Long-term efficacy of sirolimus-eluting stents (Cypher) versus bare metal stents for patients with ST-segment elevation myocardial infarction]. | Zhonghua xin xue guan bing za zhi 20080201 |
| [Effects of mTOR inhibitor rapamycin on Smad 3 protein and collagen type I expression in rat myocardial fibroblasts infected with coxsackie virus B 3]. | Zhonghua xin xue guan bing za zhi 20080201 |
| Six-month comparison of coronary endothelial dysfunction associated with sirolimus-eluting stent versus Paclitaxel-eluting stent. | JACC. Cardiovascular interventions 20080201 |
| Comparison of paclitaxel- and sirolimus-eluting stents in everyday clinical practice: the SORT OUT II randomized trial. | JAMA 20080130 |
| Effectiveness of drug-eluting stents in real-world patients. | JAMA 20080130 |
| Long-term survival of limb allografts induced by pharmacologically conditioned, donor alloantigen-pulsed dendritic cells without maintenance immunosuppression. | Transplantation 20080127 |
| Comparison of sirolimus alone with sirolimus plus tacrolimus in type 1 diabetic recipients of cultured islet cell grafts. | Transplantation 20080127 |
| Sympathetic dystrophy associated with sirolimus therapy. | Transplantation 20080127 |
| Angioplasty for the late stent thrombosis, the new technical challenge: a single centre experience. | International journal of cardiology 20080124 |
| Structural characterization of the interaction of mTOR with phosphatidic acid and a novel class of inhibitor: compelling evidence for a central role of the FRB domain in small molecule-mediated regulation of mTOR. | Oncogene 20080124 |
| Concerns in the SESAMI trial. | Journal of the American College of Cardiology 20080122 |
| mTOR: the mammalian target of replication. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080120 |
| Phase I trial of the novel mammalian target of rapamycin inhibitor deforolimus (AP23573; MK-8669) administered intravenously daily for 5 days every 2 weeks to patients with advanced malignancies. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080120 |
| Kidney-targeted Birt-Hogg-Dube gene inactivation in a mouse model: Erk1/2 and Akt-mTOR activation, cell hyperproliferation, and polycystic kidneys. | Journal of the National Cancer Institute 20080116 |
| Surface immobilization of chondroitin 6-sulfate/heparin multilayer on stainless steel for developing drug-eluting coronary stents. | Colloids and surfaces. B, Biointerfaces 20080115 |
| A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycin. | Human molecular genetics 20080115 |
| Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival. | Blood 20080115 |
| Rapamycin inhibits PAI-1 expression and reduces interstitial fibrosis and glomerulosclerosis in chronic allograft nephropathy. | Transplantation 20080115 |
| Rapamycin, but not cyclosporine or FK506, alters natural killer cell function. | Transplantation 20080115 |
| Mammalian target of rapamycin is the key effector of phosphatidylinositol-3-OH-initiated proliferative signals in the thyroid follicular epithelium. | Cancer research 20080115 |
| Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway. | The Journal of biological chemistry 20080111 |
| Sirolimus for angiomyolipoma in tuberous sclerosis complex or lymphangioleiomyomatosis. | The New England journal of medicine 20080110 |
| Efficacy of sirolimus in treating tuberous sclerosis and lymphangioleiomyomatosis. | The New England journal of medicine 20080110 |
| Sirolimus therapy in tuberous sclerosis or sporadic lymphangioleiomyomatosis. | The New England journal of medicine 20080110 |
| TORC1 is essential for NF1-associated malignancies. | Current biology : CB 20080108 |
| Effects of sirolimus-eluting stent on calcified coronary lesions. | Chinese medical journal 20080105 |
| Coupling of mammalian target of rapamycin with phosphoinositide 3-kinase signaling pathway regulates protein phosphatase 2A- and glycogen synthase kinase-3 -dependent phosphorylation of Tau. | The Journal of biological chemistry 20080104 |
| Refeeding and insulin activate the AKT/p70S6 kinase pathway without affecting IRS1 tyrosine phosphorylation in chicken muscle. | Domestic animal endocrinology 20080101 |
| Pharmacometrics and delivery of novel nanoformulated PEG-b-poly(epsilon-caprolactone) micelles of rapamycin. | Cancer chemotherapy and pharmacology 20080101 |
| Can mTOR inhibitors reduce the risk of late kidney allograft failure? | Transplant international : official journal of the European Society for Organ Transplantation 20080101 |
| Plasticity of ovarian cancer cell SKOV3ip and vasculogenic mimicry in vivo. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20080101 |
| Are impaired endothelial progenitor cells involved in the processes of late in-stent thrombosis and re-endothelialization of drug-eluting stents? | Medical hypotheses 20080101 |
| Mammalian target of rapamycin (mTOR) inhibition activates phosphatidylinositol 3-kinase/Akt by up-regulating insulin-like growth factor-1 receptor signaling in acute myeloid leukemia: rationale for therapeutic inhibition of both pathways. | Blood 20080101 |
| Adjuvant conversion to sirolimus in liver transplant patients with recurrent hepatocellular carcinoma - preliminary results. | Transplant international : official journal of the European Society for Organ Transplantation 20080101 |
| The role of cell signaling in poxvirus tropism: the case of the M-T5 host range protein of myxoma virus. | Biochimica et biophysica acta 20080101 |
| Head-to-head comparison of sirolimus- and paclitaxel-eluting stent in the same diabetic patient with multiple coronary artery lesions: a prospective, randomized, multicenter study. | Diabetes care 20080101 |
| Role of mTOR in physiology and pathology of the nervous system. | Biochimica et biophysica acta 20080101 |
| Association study of ABCB1 and CYP3A5 gene polymorphisms with sirolimus trough concentration and dose requirements in Chinese renal transplant recipients. | Biopharmaceutics & drug disposition 20080101 |
| Translational activation of 5'-TOP mRNA in pressure overload myocardium. | Basic research in cardiology 20080101 |
| Neointimal expression of rapamycin receptor FK506-binding protein FKBP12: postinjury animal and human in-stent restenosis tissue characteristics. | Journal of vascular research 20080101 |
| Differential impact of mammalian target of rapamycin inhibition on CD4+CD25+Foxp3+ regulatory T cells compared with conventional CD4+ T cells. | Blood 20080101 |
| Simultaneous hybrid coronary revascularization using totally endoscopic left internal mammary artery bypass grafting and placement of rapamycin eluting stents in the same interventional session. The COMBINATION pilot study. | Cardiology 20080101 |
| Myxoma virus oncolysis of primary and metastatic B16F10 mouse tumors in vivo. | Molecular therapy : the journal of the American Society of Gene Therapy 20080101 |
| Octreotide and the mTOR inhibitor RAD001 (everolimus) block proliferation and interact with the Akt-mTOR-p70S6K pathway in a neuro-endocrine tumour cell Line. | Neuroendocrinology 20080101 |
| The oral mTOR inhibitor RAD001 (everolimus) in combination with letrozole in patients with advanced breast cancer: results of a phase I study with pharmacokinetics. | European journal of cancer (Oxford, England : 1990) 20080101 |
| Novel methods for tracking long-term maintenance immunosuppression regimens. | Clinical journal of the American Society of Nephrology : CJASN 20080101 |
| Comparison of vascular response to zotarolimus-eluting stent versus sirolimus-eluting stent: intravascular ultrasound results from ENDEAVOR III. | American heart journal 20080101 |
| Insulin and IGF-1 enhance the expression of the neuronal monocarboxylate transporter MCT2 by translational activation via stimulation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin pathway. | The European journal of neuroscience 20080101 |
| Restenosis of the CYPHER-Select, TAXUS-Express, and Polyzene-F nanocoated cobalt-chromium stents in the minipig coronary artery model. | Cardiovascular and interventional radiology 20080101 |
| Ex vivo rapamycin generates apoptosis-resistant donor Th2 cells that persist in vivo and prevent hemopoietic stem cell graft rejection. | Journal of immunology (Baltimore, Md. : 1950) 20080101 |
| Huge right atrial thrombus 6 years after heart transplantation. | The Annals of thoracic surgery 20080101 |
| Clinical outcomes after heterogeneous overlap stenting with drug-eluting stents and bare-metal stents for de novo coronary artery narrowings. | The American journal of cardiology 20080101 |
| Short- and long-term outcomes after stent-assisted percutaneous treatment of saphenous vein grafts in the drug-eluting stent era. | The American journal of cardiology 20080101 |
| Results of percutaneous coronary intervention of the unprotected left main coronary artery in 143 patients and comparison of 30-day mortality to results of coronary artery bypass grafting. | The American journal of cardiology 20080101 |
| Sirolimus-eluting stents vs bare metal stents for coronary intervention in Japanese patients with renal failure on hemodialysis. | Circulation journal : official journal of the Japanese Circulation Society 20080101 |
| Late stent thrombosis in patients receiving ticlopidine and aspirin after sirolimus-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20080101 |
| Evaluation of antileukaemic effects of rapamycin in patients with imatinib-resistant chronic myeloid leukaemia. | European journal of clinical investigation 20080101 |
| Changes in CCR2 chemokine receptor expression and plasma MCP-1 concentration after the implantation of bare metal stents versus sirolimus-eluting stents in patients with stable angina. | Internal medicine (Tokyo, Japan) 20080101 |
| Sirolimus-induced inflammatory papules with acquired reactive perforating collagenosis. | Dermatology (Basel, Switzerland) 20080101 |
| San Antonio Breast Cancer Symposium. | The Lancet. Oncology 20080101 |
| Impact of lesion calcification on clinical and angiographic outcome after sirolimus-eluting stent implantation in real-world patients. | Cardiovascular revascularization medicine : including molecular interventions 20080101 |
| Drug-eluting stents are associated with similar cardiovascular outcomes when compared to bare metal stents in the setting of acute myocardial infarction. | Cardiovascular revascularization medicine : including molecular interventions 20080101 |
| Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma. | PLoS medicine 20080101 |
| Incorporating molecular tools into early-stage clinical trials. | PLoS medicine 20080101 |
| Calcineurin inhibitor-sparing regimens in solid organ transplantation: focus on improving renal function and nephrotoxicity. | Clinical transplantation 20080101 |
| A sensitive high-throughput HPLC assay for simultaneous determination of everolimus and clobetasol propionate. | Journal of chromatographic science 20080101 |
| Can the wound healing response of human skin be modulated after laser treatment and the effects of exposure extended? Implications on the combined use of the pulsed dye laser and a topical angiogenesis inhibitor for treatment of port wine stain birthmarks. | Lasers in surgery and medicine 20080101 |
| Tuberous sclerosis: a primary pathology of astrocytes? | Epilepsia 20080101 |
| Topical rapamycin inhibits tuberous sclerosis tumor growth in a nude mouse model. | BMC dermatology 20080101 |
| [Molecular targeted therapy for renal cell carcinoma]. | Hinyokika kiyo. Acta urologica Japonica 20080101 |
| The effect of sirolimus in the development of chronic allograft nephropathy. | Transplantation proceedings 20080101 |
| The mTOR inhibitor everolimus attenuates the time course of chronic anti-Thy1 nephritis in the rat. | Nephron. Experimental nephrology 20080101 |
| Hsf1 activation inhibits rapamycin resistance and TOR signaling in yeast revealed by combined proteomic and genetic analysis. | PloS one 20080101 |
| Comparison of long-term angiographic follow-up after sirolimus-eluting stent and bare-metal stent implantation. | Internal medicine (Tokyo, Japan) 20080101 |
| Obesity following kidney transplantation and steroid avoidance immunosuppression. | Clinical transplantation 20080101 |
| Early, abrupt conversion of de novo renal transplant patients from cyclosporine to everolimus: results of a pilot study. | Clinical transplantation 20080101 |
| mTOR inhibitors and calcineurin inhibitors do not affect adhesion molecule expression of human macro- and microvascular endothelial cells. | Journal of vascular research 20080101 |
| SIRT1 overexpression antagonizes cellular senescence with activated ERK/S6k1 signaling in human diploid fibroblasts. | PloS one 20080101 |
| Mycophenolate mofetil vs. sirolimus in kidney transplant recipients receiving tacrolimus-based immunosuppressive regimen. | Clinical transplantation 20080101 |
| Use of low dose tacrolimus, mycophenolate mofetil and maintenance IL-2 receptor blockade in an islet transplant recipient. | Clinical transplantation 20080101 |
| Generalized lymphedema in a sirolimus-treated renal transplant patient. | Clinical transplantation 20080101 |
| The combination of sirolimus and cyclosporine does not delay initial renal graft function recovery. | Renal failure 20080101 |
| [Rapamycin and lymphangiogenesis: side effect or treatment result?]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101 |
| Solution structure of the Legionella pneumophila Mip-rapamycin complex. | BMC structural biology 20080101 |
| Pathobiology and prognosis of chromophobe renal cell carcinoma. | Urologic oncology 20080101 |
| Temsirolimus: in advanced renal cell carcinoma. | Drugs 20080101 |
| The PI-3kinase pathway in hematopoietic stem cells and leukemia-initiating cells: a mechanistic difference between normal and cancer stem cells. | Blood cells, molecules & diseases 20080101 |
| Crush stenting with paclitaxel-eluting or sirolimus-eluting stents for the treatment of coronary bifurcation lesions. | Angiology 20080101 |
| Characterization of the Rheb-mTOR signaling pathway in mammalian cells: constitutive active mutants of Rheb and mTOR. | Methods in enzymology 20080101 |
| Total synthesis studies on macrocyclic pipecolic acid natural products: FK506, the antascomicins and rapamycin. | Progress in drug research. Fortschritte der Arzneimittelforschung. Progres des recherches pharmaceutiques 20080101 |
| Drug-eluting stents - what should be improved? | Annals of medicine 20080101 |
| Persistent peritoneal dialysis catheter exit-site leak in a patient receiving maintenance immunosuppression with sirolimus. | Clinical transplantation 20080101 |
| The evolution of immunosuppressant therapy in renal transplantation. | Drugs 20080101 |
| Malignancy in kidney transplant recipients. | Drugs 20080101 |
| Mechanisms and management of proteinuria in kidney transplant patients. | Drugs 20080101 |
| Sirolimus use in recipients of expanded criteria donor kidneys. | Drugs 20080101 |
| Better understanding of ADPKD results in potential new treatment options: ready for the cure? | Journal of nephrology 20080101 |
| Comparison of bare-metal and sirolimus- or paclitaxel-eluting stents for aorto-ostial coronary disease. | Cardiology 20080101 |
| A preliminary experience report: Drug-eluting stents versus coronary artery bypass surgery in patients with a single lesion in the proximal left anterior descending artery suffering from diabetes mellitus and chronic stable angina. | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20080101 |
| The mTOR signaling network: insights from its role during embryonic development. | Current medicinal chemistry 20080101 |
| Pharmacokinetics of mycophenolic acid, tacrolimus and sirolimus after gastric bypass surgery in end-stage renal disease and transplant patients: a pilot study. | Clinical transplantation 20080101 |
| Neovascular age-related macular degeneration: potential therapies. | Drugs 20080101 |
| Successful treatment of a coronary cameral fistula secondary to elective sirolimus-eluting stent implantation. | Cardiovascular revascularization medicine : including molecular interventions 20080101 |
| Efficacy and safety of drug-eluting stents in long-term follow-up. | Internal medicine (Tokyo, Japan) 20080101 |
| Stability of sirolimus and everolimus measured by immunoassay techniques in whole blood samples from kidney transplant patients. | International journal of immunopathology and pharmacology 20080101 |
| Activation of the mammalian target of rapamycin complex 1 is both necessary and sufficient to stimulate eukaryotic initiation factor 2Bvarepsilon mRNA translation and protein synthesis. | The international journal of biochemistry & cell biology 20080101 |
| Resistance exercise biology: manipulation of resistance exercise programme variables determines the responses of cellular and molecular signalling pathways. | Sports medicine (Auckland, N.Z.) 20080101 |
| Sirolimus induced dyslipidemia in tacrolimus based vs. tacrolimus free immunosuppressive regimens in renal transplant recipients. | Annals of transplantation 20080101 |
| Meta-analysis shows similar risk of thrombosis after drug-eluting stent, bare-metal stent, or angioplasty. | Endothelium : journal of endothelial cell research 20080101 |
| Rapamycin delays growth of Wnt-1 tumors in spite of suppression of host immunity. | BMC cancer 20080101 |
| On the action of cyclosporine A, rapamycin and tacrolimus on M. avium including subspecies paratuberculosis. | PloS one 20080101 |
| Effect of rifampicin to inhibit rapamycin-induced autophagy via the suppression of protein phosphatase 2A activity. | Immunopharmacology and immunotoxicology 20080101 |
| An update on the medical therapy of advanced metastatic renal cell carcinoma. | Scandinavian journal of urology and nephrology 20080101 |
| Comparison between a liquid chromatography-tandem mass spectrometry assay and a fluorescent polarization immunoassay to measure whole blood everolimus concentration in heart and renal transplantations. | Journal of clinical laboratory analysis 20080101 |
| IGF-I receptor inhibition combined with rapamycin or temsirolimus inhibits neuroblastoma cell growth. | Anticancer research 20080101 |
| Nonimmunosuppressive effects of mammalian target of rapamycin inhibitors. | Transplantation reviews (Orlando, Fla.) 20080101 |
| Deciphering downstream gene targets of PI3K/mTOR/p70S6K pathway in breast cancer. | BMC genomics 20080101 |
| Negative inotropic effect of rapamycin on isolated human cardiomyocytes. | The Journal of international medical research 20080101 |
| Mammalian target of rapamycin as a target in hematological malignancies. | Current problems in cancer 20080101 |
| Selective corticosteroid and calcineurin-inhibitor withdrawal after pancreas-kidney transplantation utilizing thymoglobulin induction and sirolimus maintenance therapy. | Clinical transplantation 20080101 |
| [To stay immature: the first step to tolerate?]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101 |
| Effects of everolimus monotherapy on hematological parameters and iron homeostasis in de novo liver transplant recipients: preliminary results. | Transplantation proceedings 20080101 |
| Sirolimus therapy in liver transplant patients: an initial experience at a single center. | Transplantation proceedings 20080101 |
| [Role of PTEN protein in multidrug resistance of prostate cancer cells]. | Molekuliarnaia biologiia 20080101 |
| Current management of tuberous sclerosis complex. | Paediatric drugs 20080101 |
| TOR signaling in fission yeast. | Critical reviews in biochemistry and molecular biology 20080101 |
| Drug eluting and bare metal stents in people with and without diabetes: collaborative network meta-analysis. | BMJ (Clinical research ed.) 20080101 |
| The South African branch of the Crossroads Institute celebrates it second birthday. | Cardiovascular journal of Africa 20080101 |
| [Tirofiban or abciximab and sirolimus-eluting or bare metal uncoated stents in primary percutaneous coronary intervention for acute myocardial infarction: results of MULTISTRATEGY trial]. | Kardiologiia 20080101 |
| Clinical results of drug eluting stents compared to bare metal stents for patients with ST elevation acute myocardial infarction. | Acute cardiac care 20080101 |
| Influence of interactions between immunosuppressive drugs on therapeutic drug monitoring. | Annals of transplantation 20080101 |
| Orally administered rapamycin, dacarbazine or both for treatment of human melanoma evaluated in severe combined immunodeficiency mice. | Pharmacology 20080101 |
| Monotherapy with anti-LFA-1 monoclonal antibody promotes long-term survival of rat islet xenografts. | Cell transplantation 20080101 |
| Quantification of sirolimus and everolimus by immunoassay techniques: test specificity and cross-reactivity evaluation. | International journal of immunopathology and pharmacology 20080101 |
| Signaling inhibitors in metastatic renal cell carcinoma. | Cancer journal (Sudbury, Mass.) 20080101 |
| From Easter Island to coated coronary stents: a remarkable saga. | Journal of the Medical Association of Georgia 20080101 |
| A rapid liquid chromatography-tandem mass spectrometry analysis of whole blood sirolimus using turbulent flow technology for online extraction. | Clinical chemistry and laboratory medicine 20080101 |
| TOR regulates cell death induced by telomere dysfunction in budding yeast. | PloS one 20080101 |
| Efficacy of rapamycin in scleroderma: a case study. | Lymphatic research and biology 20080101 |
| Effects of everolimus as an antiproliferative agent on regression of encapsulating peritoneal sclerosis in a rat model. | Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20080101 |
| Failure of systematic error detection with internal quality control program. | Annals of clinical and laboratory science 20080101 |
| [Chronic allograft dysfunction: role of immunosuppressive treatment]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20080101 |
| Prolyl isomerase Pin1 is highly expressed in Her2-positive breast cancer and regulates erbB2 protein stability. | Molecular cancer 20080101 |
| [ASCO 2008. Bevacizumab in advanced renal carcinoma]. | Tumori 20080101 |
| PTEN and rapamycin inhibiting the growth of K562 cells through regulating mTOR signaling pathway. | Journal of experimental & clinical cancer research : CR 20080101 |
| Effect of intestinal and hepatic first-pass extraction on the pharmacokinetics of everolimus in rats. | Drug metabolism and pharmacokinetics 20080101 |
| [Experience with primary coronary angioplasty in management of patients suffering from acute myocardial infarction]. | Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101 |
| [Problem of restenosis inside stents with an antiproliferative coating]. | Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101 |
| Methods to investigate autophagy during starvation and regeneration in hydra. | Methods in enzymology 20080101 |
| mTOR inhibition sensitizes gastric cancer to alkylating chemotherapy in vivo. | Anticancer research 20080101 |
| A case of complete revascularization with nine sirolimus eluting stents. | Indian heart journal 20080101 |
| Sirolimus-loaded polyurethane graft for hemodialysis access in sheep. | Vascular 20080101 |
| Two-year (mid-term) results for unprotected left main coronary artery percutaneous interventions with drug-eluting stents. | Indian heart journal 20080101 |
| Preclinical and early clinical experience with a biodegradable polymer-based, rapamycin-eluting, Indian drug-eluting coronary stent: the BIO-RAPID study. | Indian heart journal 20080101 |
| [Experience in using stents with an antiproliferative coating in treatment of stenoses and occlusions of coronary arteries. Review of the literature]. | Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20080101 |
| Chemically induced and light-independent cryptochrome photoreceptor activation. | Molecular plant 20080101 |
| Rapamycin impairs in vivo proliferation of islet beta-cells. | Transplantation 20071227 |
| Long-term limb allograft survival using a short course of anti-CD45RB monoclonal antibody, LF 15-0195, and rapamycin in a mouse model. | Transplantation 20071227 |
| Apoptosis and autophagy as mechanisms of dinoflagellate symbiont release during cnidarian bleaching: every which way you lose. | Proceedings. Biological sciences 20071222 |
| Targeted drugs for metastatic renal cell carcinoma. | Lancet (London, England) 20071222 |
| Safety of drug-eluting stents: demystifying network meta-analysis. | Lancet (London, England) 20071222 |
| The pancreatitis-induced vacuole membrane protein 1 triggers autophagy in mammalian cells. | The Journal of biological chemistry 20071221 |
| Reduced exposure to calcineurin inhibitors in renal transplantation. | The New England journal of medicine 20071220 |
| Balancing efficacy and toxicity in kidney-transplant immunosuppression. | The New England journal of medicine 20071220 |
| Advancing the knowledge base on the efficacy-safety ratio with drug-eluting stents contributions from the European Society of Cardiology Congress, Vienna, Austria, September 1-5, 2007. | Journal of the American College of Cardiology 20071218 |
| Temsirolimus (Torisel) for advanced renal cell carcinoma. | The Medical letter on drugs and therapeutics 20071217 |
| Angiographic and intravascular ultrasound study of the effects of overlapping sirolimus- and paclitaxel-eluting stents: comparison with same drug-eluting overlapping stents. | International journal of cardiology 20071215 |
| Comparison of bypass surgery with drug-eluting stents for diabetic patients with multivessel disease. | International journal of cardiology 20071215 |
| Determination of the rate constants for the FK506 binding protein/rapamycin interaction using surface plasmon resonance: an alternative sensor surface for Ni2+-nitrilotriacetic acid immobilization of His-tagged proteins. | Analytical biochemistry 20071215 |
| The selectivity of protein kinase inhibitors: a further update. | The Biochemical journal 20071215 |
| Rapamycin inhibits differentiation of Th17 cells and promotes generation of FoxP3+ T regulatory cells. | International immunopharmacology 20071215 |
| A lower incidence of cytomegalovirus infection in de novo heart transplant recipients randomized to everolimus. | Transplantation 20071215 |
| The mTOR inhibitor everolimus induces proteinuria and renal deterioration in the remnant kidney model in the rat. | Transplantation 20071215 |
| Pharmacokinetic and tumor distribution characteristics of temsirolimus in patients with recurrent malignant glioma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071215 |
| Rapamycin promotes vascular smooth muscle cell differentiation through insulin receptor substrate-1/phosphatidylinositol 3-kinase/Akt2 feedback signaling. | The Journal of biological chemistry 20071207 |
| Minor contribution of an internal ribosome entry site in the 5'-UTR of ornithine decarboxylase mRNA on its translation. | Biochemical and biophysical research communications 20071207 |
| Sirolimus-induced drug fever and ciclosporin-induced leukencephalopathia with seizures in one liver transplant recipient. | World journal of gastroenterology 20071207 |
| Conversion to sirolimus as primary immunosuppression attenuates the progression of allograft vasculopathy after cardiac transplantation. | Circulation 20071204 |
| Sirolimus and cardiac transplantation: is it the 'magic bullet'? | Circulation 20071204 |
| Decreased levels of hypoxic cells in gefitinib treated ER+ HER-2 overexpressing MCF-7 breast cancer tumors are associated with hyperactivation of the mTOR pathway: therapeutic implications for combination therapy with rapamycin. | Breast cancer research and treatment 20071201 |
| Pharmacokinetics, safety, and efficacy of mycophenolate mofetil in combination with sirolimus or ciclosporin in renal transplant patients. | British journal of clinical pharmacology 20071201 |
| Sirolimus (rapamycin): from the soil of Easter Island to a bright future. | Journal of the American Academy of Dermatology 20071201 |
| Pneumonitis associated with sirolimus: clinical characteristics, risk factors and outcome--a single-centre experience and review of the literature. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071201 |
| Efficacy of reduced-dose sirolimus-eluting stents in the human coronary artery: serial IVUS analysis of neointimal hyperplasia and luminal dimension. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071201 |
| Long-term clinical follow-up of sirolimus-eluting (CYPHER) coronary stents in the treatment of instent restenosis in an unselected population. | Heart, lung & circulation 20071201 |
| Functional and phenotypic characteristics of CD4+CD25highFoxp3+ Treg clones obtained from peripheral blood of patients with cancer. | International journal of cancer 20071201 |
| Proteinuria after kidney transplantation, relationship to allograft histology and survival. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201 |
| Clinically relevant immunosuppressants influence UVB-induced tumor size through effects on inflammation and angiogenesis. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201 |
| Immunosuppressant pharmacokinetics and dosing modifications in HIV-1 infected liver and kidney transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071201 |
| Genetically encoded molecules for inducibly inactivating CaV channels. | Nature chemical biology 20071201 |
| Effects of rapamycin on gene expression, morphology, and electrophysiological properties of rat hippocampal neurons. | Epilepsy research 20071201 |
| Immunosuppressive agents: effects on glucose and lipid metabolism. | Endocrinology and metabolism clinics of North America 20071201 |
| Regulation of elongation phase of mRNA translation in diabetic nephropathy: amelioration by rapamycin. | The American journal of pathology 20071201 |
| Serial long-term evaluation of neointimal stent coverage and thrombus after sirolimus-eluting stent implantation by use of coronary angioscopy. | Heart (British Cardiac Society) 20071201 |
| Strut fracture of a sirolimus-eluting stent at the ostium of the right coronary artery. | Heart (British Cardiac Society) 20071201 |
| Impact of metabolic syndrome on clinical and angiographic outcome after sirolimus-eluting stent implantation. | Coronary artery disease 20071201 |
| RESTEM: a percutaneous coronary intervention 'real world' registry in the drug-eluting stent era. | Coronary artery disease 20071201 |
| Chemical genetic modification of Ca2+ channel activity. | Nature chemical biology 20071201 |
| Cost-effectiveness of sirolimus-eluting stents compared with vascular brachytherapy for the treatment of in-stent restenosis. | American heart journal 20071201 |
| Comparison of effects of telmisartan and valsartan on late lumen loss and inflammatory markers after sirolimus-eluting stent implantation in hypertensive patients. | The American journal of cardiology 20071201 |
| Long-term clinical benefit of sirolimus-eluting stents compared to bare metal stents in the treatment of saphenous vein graft disease. | Journal of interventional cardiology 20071201 |
| Crossreactivity of isolated everolimus metabolites with the Innofluor Certican immunoassay for therapeutic drug monitoring of everolimus. | Therapeutic drug monitoring 20071201 |
| A randomized controlled trial of late conversion from calcineurin inhibitor (CNI)-based to sirolimus-based immunosuppression in liver transplant recipients with impaired renal function. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20071201 |
| Analysis of bifurcation lesions treated with novel drug-eluting dedicated bifurcation stent system: intravascular ultrasound results of the AXXESS PLUS trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071201 |
| Percutaneous coronary intervention in the 21st century - making surgeons irrelevant? | Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine 20071201 |
| Targeting protein translation in human non small cell lung cancer via combined MEK and mammalian target of rapamycin suppression. | Cancer research 20071201 |
| Pravastatin induces rat aortic endothelial cell proliferation and migration via activation of PI3K/Akt/mTOR/p70 S6 kinase signaling. | Journal of pharmacological sciences 20071201 |
| Small-molecule and antibody approaches to molecular chemotherapy of primary brain tumors. | Current opinion in investigational drugs (London, England : 2000) 20071201 |
| Sirolimus-eluting versus bare-metal stents for the reduction of coronary restenosis: 18-month angiographic results from the GERSHWIN Study. | Herz 20071201 |
| Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits. | Genes to cells : devoted to molecular & cellular mechanisms 20071201 |
| [mTOR signal pathway and its inhibitors in antitumor therapy: a review]. | Ai zheng = Aizheng = Chinese journal of cancer 20071201 |
| [Rapamycin affects eIF- 4E expression in rat myocardial fibroblasts infected by Coxsackievirus B3]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20071201 |
| Proliferation signal inhibitors in transplantation: questions at the cutting edge of everolimus therapy. | Transplantation proceedings 20071201 |
| Statins benefit outcomes of renal transplant recipients on a sirolimus-cyclosporine regimen. | Transplantation proceedings 20071201 |
| Posttransplantation conversion to sirolimus-based immunosuppression: a single center experience. | Transplantation proceedings 20071201 |
| Economic evaluation of everolimus and mycophenolate mofetil versus azathioprine in de novo heart transplantation. | Transplantation proceedings 20071201 |
| Anti-CD25 mAb, anti-IL2 mAb, and IL2 block tolerance induction through anti-CD154 mAb and rapamycin in xenogeneic islet transplantation. | Transplantation proceedings 20071201 |
| An unusual presentation of sirolimus associated cough in a renal transplant recipient. | Transplantation proceedings 20071201 |
| Interstitial pneumonitis associated with sirolimus in liver transplantation: a case report. | Transplantation proceedings 20071201 |
| Switch to everolimus for sirolimus-induced pneumonitis in a liver transplant recipient--not all proliferation signal inhibitors are the same: a case report. | Transplantation proceedings 20071201 |
| [Therapeutic effect of sirolimus against chronic allograft nephropathy in kidney transplant recipients]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071201 |
| Acute thrombosis of a mesenteric artery drug-eluting stent following clopidogrel cessation. | Vascular and endovascular surgery 20071201 |
| Characterization of late incomplete stent apposition: a comparison among bare-metal stents, intracoronary radiation and sirolimus-eluting stents. | The Journal of invasive cardiology 20071201 |
| The Cairo kidney center protocol for rapamycin-based sequential immunosuppression in kidney transplant recipients: 2-year outcomes. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20071201 |
| New strategies for the treatment of metastatic bone disease. | Clinical breast cancer 20071201 |
| [Synergistic effect of rapamycin (RPM) and PD98059 on cell cycle and mTOR signal transduction in human colorectal cancer cells]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20071201 |
| Clinically significant proteinuria following the administration of sirolimus to renal transplant recipients. | Drug metabolism letters 20071201 |
| mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex. | Nature 20071129 |
| Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53. | The EMBO journal 20071128 |
| Gender-specific outcomes after sirolimus-eluting stent implantation. | Journal of the American College of Cardiology 20071127 |
| Peeling-off labels mounting evidence for benefit of drug-eluting stents with off-label use. | Journal of the American College of Cardiology 20071120 |
| Sirolimus-eluting stent treatment as buffer for inflamed lesions identified by serum marker estimation. The STABILISE pilot study. | International journal of cardiology 20071115 |
| Steroid-free maintenance immunosuppression with rapamune and low-dose neoral in pancreas transplant recipients. | Transplantation 20071115 |
| Drug eluting stents versus coronary artery bypass surgery in patients with isolated proximal lesion in left anterior descending artery suffering from chronic stable angina. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071115 |
| Cell signaling. mTOR, unleashed. | Science (New York, N.Y.) 20071109 |
| Rheb activates mTOR by antagonizing its endogenous inhibitor, FKBP38. | Science (New York, N.Y.) 20071109 |
| Intravascular drug release kinetics dictate arterial drug deposition, retention, and distribution. | Journal of controlled release : official journal of the Controlled Release Society 20071106 |
| Cost-effectiveness of drug-eluting stents in patients at high or low risk of major cardiac events in the Basel Stent KostenEffektivitäts Trial (BASKET): an 18-month analysis. | Lancet (London, England) 20071103 |
| Sirolimus blocks the accumulation of hyaluronan (HA) by arterial smooth muscle cells and reduces monocyte adhesion to the ECM. | Atherosclerosis 20071101 |
| Preparation and characterization of rapamycin-loaded PLGA coating stent. | Journal of materials science. Materials in medicine 20071101 |
| Blockade of chronic graft-versus-host disease by alloantigen-induced CD4+CD25+Foxp3+ regulatory T cells in nonlymphopenic hosts. | Journal of leukocyte biology 20071101 |
| A plant triterpenoid, avicin D, induces autophagy by activation of AMP-activated protein kinase. | Cell death and differentiation 20071101 |
| Everolimus-associated interstitial pneumonitis in a patient with a heart transplant. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20071101 |
| Sirolimus versus cyclosporine in kidney recipients receiving thymoglobulin, mycophenolate mofetil and a 6-month course of steroids. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071101 |
| Molecular targeted therapy of head and neck cancer: review and clinical development challenges. | European journal of cancer (Oxford, England : 1990) 20071101 |
| Sirolimus in chronic allograft nephropathy in pediatric recipients. | Pediatric transplantation 20071101 |
| Pharmacokinetic profile of temsirolimus with concomitant administration of cytochrome p450-inducing medications. | Journal of clinical pharmacology 20071101 |
| Randomized trial of rapamycin- and paclitaxel-eluting stents with identical biodegradable polymeric coating and design. | European heart journal 20071101 |
| RyR1-specific requirement for depolarization-induced Ca2+ sparks in urinary bladder smooth muscle. | Journal of cell science 20071101 |
| Implantation of sirolimus-eluting stents in saphenous vein grafts is associated with high clinical follow-up event rates compared with treatment of native vessels. | Coronary artery disease 20071101 |
| Serial long-term evaluation of neointimal stent coverage and thrombus after sirolimus-eluting stent implantation by use of coronary angioscopy. | Heart (British Cardiac Society) 20071101 |
| Distinctive expression and functional regulation of the maize (Zea mays L.) TOR kinase ortholog. | Molecular bioSystems 20071101 |
| Impact of the metabolic syndrome on angiographic and clinical events after coronary intervention using bare-metal or sirolimus-eluting stents. | The American journal of cardiology 20071101 |
| Post-renal transplant hemolytic uremic syndrome following combination therapy with tacrolimus and everolimus. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20071101 |
| Successful treatment of post-renal transplant gastric and pulmonary Kaposi's sarcoma with conversion to rapamycin treatment. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20071101 |
| TOR signalling regulates mitotic commitment through the stress MAP kinase pathway and the Polo and Cdc2 kinases. | Nature cell biology 20071101 |
| Coronary artery bypass grafting versus coronary implantation of sirolimus-eluting stents in patients with diabetic retinopathy. | The Annals of thoracic surgery 20071101 |
| Three-year clinical outcomes after coronary stenting of chronic total occlusion using sirolimus-eluting stents: insights from the rapamycin-eluting stent evaluated at Rotterdam cardiology hospital-(RESEARCH) registry. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071101 |
| Why do DES not alter long-term outcomes? Why would they, after all, it's a chronic disease. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071101 |
| Sirolimus inhibits human pancreatic carcinoma cell proliferation by a mechanism linked to the targeting of mTOR/HIF-1 alpha/VEGF signaling. | IUBMB life 20071101 |
| Laparoscopic incisional hernia repair after liver transplantation. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20071101 |
| A randomized, phase II trial of two dose levels of temsirolimus (CCI-779) in patients with extensive-stage small-cell lung cancer who have responding or stable disease after induction chemotherapy: a trial of the Eastern Cooperative Oncology Group (E1500). | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20071101 |
| Treatment of restenotic drug-eluting stents: an intravascular ultrasound analysis. | The Journal of invasive cardiology 20071101 |
| The influence of immuosuppressive therapy on the development of CD4+CD25+ T cells after renal transplantation. | Transplantation proceedings 20071101 |
| Anticancer effect of sirolimus in renal allograft recipients with de novo malignancies. | Transplantation proceedings 20071101 |
| Comparison of long-term results of drug-eluting stent and bare metal stent implantation in heart transplant recipients with coronary artery disease. | Transplantation proceedings 20071101 |
| Bevacizumab and rapamycin inhibit tumor growth in peritoneal model of human ovarian cancer. | Molecular cancer therapeutics 20071101 |
| Autophagy in cardiovascular disease. | Trends in molecular medicine 20071101 |
| Cancer after renal transplantation. | Current opinion in nephrology and hypertension 20071101 |
| Comparison of long-term clinical outcome after sirolimus-eluting stent implantation in patients with and without hemodialysis. | International heart journal 20071101 |
| Late multiple stent fractures following deployment of sirolimus-eluting stents for diffuse right coronary artery stenosis. | International heart journal 20071101 |
| Temsirolimus for advanced renal cell carcinoma. | Clinical advances in hematology & oncology : H&O 20071101 |
| A randomized phase II study of pemetrexed or RAD001 as second-line treatment of advanced non-small-cell lung cancer in elderly patients: treatment rationale and protocol dynamics. | Clinical lung cancer 20071101 |
| [Clinical features of late stent thrombosis after successful sirolimus-eluting stent implantation]. | Zhonghua xin xue guan bing za zhi 20071101 |
| Sirolimus versus cyclosporine therapy increases circulating regulatory T cells, but does not protect renal transplant patients given alemtuzumab induction from chronic allograft injury. | Transplantation 20071027 |
| Sirolimus modifies cholesterol homeostasis in hepatic cells: a potential molecular mechanism for sirolimus-associated dyslipidemia. | Transplantation 20071027 |
| One-year results of the SCORPIUS study: a German multicenter investigation on the effectiveness of sirolimus-eluting stents in diabetic patients. | Journal of the American College of Cardiology 20071023 |
| Features and parameters of drug-eluting stent deployment discoverable by intravascular ultrasound. | The American journal of cardiology 20071022 |
| The significance of preclinical evaluation of sirolimus-, paclitaxel-, and zotarolimus-eluting stents. | The American journal of cardiology 20071022 |
| Zotarolimus-eluting stents in patients with native coronary artery disease: clinical and angiographic outcomes in 1,317 patients. | The American journal of cardiology 20071022 |
| Four-year clinical follow-up after implantation of the endeavor zotarolimus-eluting stent: ENDEAVOR I, the first-in-human study. | The American journal of cardiology 20071022 |
| The relation between clinical features, angiographic findings, and the target lesion revascularization rate in patients receiving the endeavor zotarolimus-eluting stent for treatment of native coronary artery disease: an analysis of ENDEAVOR I, ENDEAVOR II, ENDEAVOR II Continued Access Registry, and ENDEAVOR III. | The American journal of cardiology 20071022 |
| Intravascular ultrasound findings in ENDEAVOR II and ENDEAVOR III. | The American journal of cardiology 20071022 |
| Real-world safety and efficacy of the endeavor zotarolimus-eluting stent: early data from the E-Five Registry. | The American journal of cardiology 20071022 |
| Phase I study of everolimus in pediatric patients with refractory solid tumors. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020 |
| Basal activation of p70S6K results in adipose-specific insulin resistance in protein-tyrosine phosphatase 1B -/- mice. | The Journal of biological chemistry 20071019 |
| Rapamycin regulates the phosphorylation of rictor. | Biochemical and biophysical research communications 20071019 |
| Normal phase and reverse phase HPLC-UV-MS analysis of process impurities for rapamycin analog ABT-578: application to active pharmaceutical ingredient process development. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015 |
| Comparison of outcomes using sirolimus-eluting stenting in diabetic versus nondiabetic patients with comparison of insulin versus non-insulin therapy in the diabetic patients. | The American journal of cardiology 20071015 |
| Thymic stromal-derived lymphopoietin induces proliferation of pre-B leukemia and antagonizes mTOR inhibitors, suggesting a role for interleukin-7Ralpha signaling. | Cancer research 20071015 |
| Sirolimus-related pulmonary toxicity mimicking 'asthma like' symptoms. | World journal of gastroenterology 20071014 |
| Posttransplant Epstein-Barr virus related lymphoproliferative disorder with a primary cutaneous presentation. | Dermatology online journal 20071013 |
| S6K1-mediated disassembly of mitochondrial URI/PP1gamma complexes activates a negative feedback program that counters S6K1 survival signaling. | Molecular cell 20071012 |
| [Impact of sirolimus on collagen synthesis in vascular smooth muscle cells: experiment with rat]. | Zhonghua yi xue za zhi 20071009 |
| mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70(S6k). | FEBS letters 20071002 |
| Long-term clinical outcomes with sirolimus-eluting coronary stents: five-year results of the RAVEL trial. | Journal of the American College of Cardiology 20071002 |
| Sirolimus-eluting stent implantation aggravates endothelial vasomotor dysfunction in the infarct-related coronary artery in patients with acute myocardial infarction. | Journal of the American College of Cardiology 20071002 |
| A meta-analysis of 16 randomized trials of sirolimus-eluting stents versus paclitaxel-eluting stents in patients with coronary artery disease. | Journal of the American College of Cardiology 20071002 |
| The Emperor's new clothes: another cypher versus taxus post-hoc meta-analysis. | Journal of the American College of Cardiology 20071002 |
| Reduced systemic inflammatory response to implantation of sirolimus-eluting stents in patients with stable coronary artery disease. | Atherosclerosis 20071001 |
| PIM-2 is an independent regulator of chondrocyte survival and autophagy in the epiphyseal growth plate. | Journal of cellular physiology 20071001 |
| Multiple sirolimus eluting stent fractures. | European heart journal 20071001 |
| Comparison of in vivo acute stent recoil between the bioabsorbable everolimus-eluting coronary stent and the everolimus-eluting cobalt chromium coronary stent: insights from the ABSORB and SPIRIT trials. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001 |
| Late vascular response at the edges of sirolimus analogous-eluting stents in diabetic patients: An intravascular ultrasound study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001 |
| Comparison of a treatment strategy combining CCI-779 plus DTIC versus DTIC monotreatment in human melanoma in SCID mice. | The Journal of investigative dermatology 20071001 |
| Steroid and oxygen effects on eIF4F complex, mTOR, and ENaC translation in fetal lung epithelia. | American journal of respiratory cell and molecular biology 20071001 |
| Determination of sirolimus in rabbit arteries using liquid chromatography separation and tandem mass spectrometric detection. | Biomedical chromatography : BMC 20071001 |
| Modulation of tolerance to the transgene product in a nonhuman primate model of AAV-mediated gene transfer to liver. | Blood 20071001 |
| The application of ink-jet technology for the coating and loading of drug-eluting stents. | Annals of biomedical engineering 20071001 |
| Translational control of nrf2 protein in activation of antioxidant response by oxidants. | Molecular pharmacology 20071001 |
| Reversal of portal hypertension and hyperdynamic splanchnic circulation by combined vascular endothelial growth factor and platelet-derived growth factor blockade in rats. | Hepatology (Baltimore, Md.) 20071001 |
| Initial clinical impact of drug eluting stents on coronary artery bypass graft surgery. | Interactive cardiovascular and thoracic surgery 20071001 |
| Early experience with conversion to sirolimus in a pediatric renal transplant population. | Pediatric nephrology (Berlin, Germany) 20071001 |
| Statin therapy, alone or with rapamycin, does not reverse monocrotaline pulmonary arterial hypertension: the rapamcyin-atorvastatin-simvastatin study. | American journal of physiology. Lung cellular and molecular physiology 20071001 |
| Methanol-associated matrix effects in electrospray ionization tandem mass spectrometry. | Clinical chemistry 20071001 |
| Azoospermia in a renal transplant recipient during sirolimus (rapamycin) treatment. | Andrologia 20071001 |
| Rapamycin: something old, something new, sometimes borrowed and now renewed. | Clinical pharmacology and therapeutics 20071001 |
| Mammalian target of rapamycin inhibition halts the progression of proteinuria in a rat model of reduced renal mass. | Journal of the American Society of Nephrology : JASN 20071001 |
| Sirolimus-associated infertility: case report and literature review of possible mechanisms. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20071001 |
| Three-year health-related quality-of-life outcomes for sirolimus-treated kidney transplant patients after elimination of cyclosporine. | Transplant international : official journal of the European Society for Organ Transplantation 20071001 |
| The role of mTOR inhibition in augmenting radiation induced autophagy. | Technology in cancer research & treatment 20071001 |
| Effects of ciclosporin A, tacrolimus and sirolimus on cytokine production in neonatal immune cells. | Acta paediatrica (Oslo, Norway : 1992) 20071001 |
| Comparison of triple versus dual antiplatelet therapy after drug-eluting stent implantation (from the DECLARE-Long trial). | The American journal of cardiology 20071001 |
| Rapamycin reduces CCR5 mRNA levels in macaques: potential applications in HIV-1 prevention and treatment. | AIDS (London, England) 20071001 |
| Sirolimus-eluting stent treatment for unprotected versus protected left main coronary artery disease in widespread clinical routine: 6-month and 3-year clinical follow-up results from the prospective multicentre German Cypher Registry. | Heart (British Cardiac Society) 20071001 |
| Outcome in the elderly undergoing percutaneous coronary intervention with sirolimus-eluting stents: results from the prospective multicenter German Cypher Stent Registry. | American heart journal 20071001 |
| Impact of diabetes mellitus on long-term outcomes in the drug-eluting stent era. | American heart journal 20071001 |
| Impact of drug-eluting stents on clinical and angiographic outcomes in dialysis patients. | Circulation journal : official journal of the Japanese Circulation Society 20071001 |
| Polymeric stents: degradable but strong. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001 |
| The SIRIUS-DIRECT trial: a multi-center study of direct stenting using the sirolimus-eluting stent in patients with de novo native coronary artery lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001 |
| Direct stenting in the DES era: Can we do better? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001 |
| The pros and cons of living on the edge. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20071001 |
| Identification of everolimus metabolite patterns in trough blood samples of kidney transplant patients. | Therapeutic drug monitoring 20071001 |
| Internal standard selection for the high-performance liquid chromatography tandem mass spectroscopy assay of everolimus in blood. | Therapeutic drug monitoring 20071001 |
| Aging increases pulmonary veins arrhythmogenesis and susceptibility to calcium regulation agents. | Heart rhythm 20071001 |
| Utility of sirolimus-eluting Cypher stents to reduce 12-month target vessel revascularization in saphenous vein graft stenoses: results of a multicenter 350-patient case-control study. | The Journal of invasive cardiology 20071001 |
| Spontaneous coronary artery perforation secondary to a sirolimus-eluting stent infection. | The Journal of invasive cardiology 20071001 |
| Preclinical testing of clinically applicable strategies for overcoming trastuzumab resistance caused by PTEN deficiency. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071001 |
| Sirolimus-based immunosuppression after cardiac transplantation: predictors of recovery from calcineurin inhibitor-induced renal dysfunction. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20071001 |
| Treatment of unprotected left main coronary artery stenosis in a 5-year-old heart transplant patient using a sirolimus-eluting stent. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20071001 |
| Sirolimus: efficacy in liver transplant patients with nephrotoxicity and renal insufficiency. | Transplantation proceedings 20071001 |
| Drug-eluting stent implantation results in effective treatment of small coronary artery disease (DESIRE Small CAD). | Connecticut medicine 20071001 |
| Sirolimus-associated diffuse alveolar hemorrhage in a renal transplant recipient on long-term anticoagulation. | Clinical nephrology 20071001 |
| Immune responses to gene product of inducible promoters. | Current gene therapy 20071001 |
| Anti-inflammatory effect of abciximab-coated stent in a porcine coronary restenosis model. | Journal of Korean medical science 20071001 |
| Temsirolimus. | Drugs of today (Barcelona, Spain : 1998) 20071001 |
| [Long-term clinical benefits of using active stents in diabetic patients: two year follow-up of a consecutive series of 122 patients]. | Archives des maladies du coeur et des vaisseaux 20071001 |
| Cancer and transplantation intersect at the mammalian target of rapamycin. | Transplantation 20070927 |
| Use of everolimus as a rescue immunosuppressive therapy in liver transplant patients with neoplasms. | Transplantation 20070927 |
| Comparative clinical outcomes of paclitaxel- and sirolimus-eluting stents: results from a large prospective multicenter registry--STENT Group. | Journal of the American College of Cardiology 20070925 |
| Detecting binding interactions using microarrays of natural product extracts. | Journal of the American Chemical Society 20070919 |
| Impact of vessel size on outcome after implantation of sirolimus-eluting and paclitaxel-eluting stents: a subgroup analysis of the SIRTAX trial. | Journal of the American College of Cardiology 20070918 |
| Drug-eluting stent update 2007: part III: Technique and unapproved/unsettled indications (left main, bifurcations, chronic total occlusions, small vessels and long lesions, saphenous vein grafts, acute myocardial infarctions, and multivessel disease). | Circulation 20070918 |
| Low-dose arsenic trioxide sensitizes glucocorticoid-resistant acute lymphoblastic leukemia cells to dexamethasone via an Akt-dependent pathway. | Blood 20070915 |
| Quantification of cyclosporine A in peripheral blood mononuclear cells by liquid chromatography-electrospray mass spectrometry using a column-switching approach. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070915 |
| Safety of drug-eluting stents in the coronary artery in ST-elevation myocardial infarction at a single high-volume medical center. | The American journal of cardiology 20070915 |
| Correlates of clinical restenosis following intracoronary implantation of drug-eluting stents. | The American journal of cardiology 20070915 |
| Drug-eluting stents and late stent thrombosis. | Lancet (London, England) 20070915 |
| Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis. | Lancet (London, England) 20070915 |
| Targeting human medulloblastoma: oncolytic virotherapy with myxoma virus is enhanced by rapamycin. | Cancer research 20070915 |
| Expansion of human T regulatory type 1 cells in the microenvironment of cyclooxygenase 2 overexpressing head and neck squamous cell carcinoma. | Cancer research 20070915 |
| Interferon-gamma induces human vascular smooth muscle cell proliferation and intimal expansion by phosphatidylinositol 3-kinase dependent mammalian target of rapamycin raptor complex 1 activation. | Circulation research 20070914 |
| Interferon-gamma and intimal hyperplasia. | Circulation research 20070914 |
| D-glucosamine inhibits proliferation of human cancer cells through inhibition of p70S6K. | Biochemical and biophysical research communications 20070907 |
| RB1CC1 insufficiency causes neuronal atrophy through mTOR signaling alteration and involved in the pathology of Alzheimer's diseases. | Brain research 20070907 |
| Temsirolimus for advanced renal-cell carcinoma. | The New England journal of medicine 20070906 |
| Temsirolimus for advanced renal-cell carcinoma. | The New England journal of medicine 20070906 |
| Coronary stent fracture and restenosis in the drug-eluting stent era: do we have clues of management? | International journal of cardiology 20070903 |
| Cardiogenic shock caused by simultaneous subacute stent thrombosis after implantation of sirolimus-eluting stents. | International journal of cardiology 20070903 |
| Comparison of angiographic patterns of in-stent restenosis between sirolimus- and paclitaxel-eluting stent. | International journal of cardiology 20070903 |
| Understanding the drug-eluting stent trials. | The American journal of cardiology 20070903 |
| Expansion and characteristics of human T regulatory type 1 cells in co-cultures simulating tumor microenvironment. | Cancer immunology, immunotherapy : CII 20070901 |
| Specific mTOR inhibitor rapamycin enhances cytotoxicity induced by alkylating agent 1-(4-amino-2-methyl-5-pyrimidinyl)methyl-3-(2-chloroethyl)-3-nitrosourea (ACNU) in human U251 malignant glioma cells. | Journal of neuro-oncology 20070901 |
| Telomere 3' overhang-specific DNA oligonucleotides induce autophagy in malignant glioma cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070901 |
| Genetic and pharmacologic evidence implicating the p85 alpha, but not p85 beta, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloid leukemia and systemic mastocytosis. | Blood 20070901 |
| Improved blood compatibility of rapamycin-eluting stent by incorporating curcumin. | Colloids and surfaces. B, Biointerfaces 20070901 |
| In vitro metabolic study of temsirolimus: preparation, isolation, and identification of the metabolites. | Drug metabolism and disposition: the biological fate of chemicals 20070901 |
| Incidence of anemia in sirolimus-treated renal transplant recipients: the importance of preserving renal function. | Transplant international : official journal of the European Society for Organ Transplantation 20070901 |
| Predictors of long-term outcome following liver transplantation for hepatocellular carcinoma: a single-center experience. | Transplant international : official journal of the European Society for Organ Transplantation 20070901 |
| Reflex sympathetic dystrophy in a renal transplant patient treated with sirolimus. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070901 |
| Golgi manganese transport is required for rapamycin signaling in Saccharomyces cerevisiae. | Genetics 20070901 |
| Prevention of TGF-beta-induced apoptosis by interlukin-4 through Akt activation and p70S6K survival signaling pathways. | Apoptosis : an international journal on programmed cell death 20070901 |
| Serotonin induces memory-like, rapamycin-sensitive hyperexcitability in sensory axons of aplysia that contributes to injury responses. | Journal of neurophysiology 20070901 |
| Treatment options in steroid-refractory acute graft-versus-host disease following hematopoietic stem cell transplantation. | The Annals of pharmacotherapy 20070901 |
| Use of sirolimus-eluting stents for treatment of in-stent restenosis: long-term follow-up. | Journal of cardiovascular medicine (Hagerstown, Md.) 20070901 |
| Treatment of restenosis after bare-metal and drug-eluting stenting of an aorto-ostial lesion: challenges associated with excessive stent overhang. | Journal of cardiovascular medicine (Hagerstown, Md.) 20070901 |
| Noble gases without anesthetic properties protect myocardium against infarction by activating prosurvival signaling kinases and inhibiting mitochondrial permeability transition in vivo. | Anesthesia and analgesia 20070901 |
| A randomized comparison of sirolimus-eluting stent implantation with zotarolimus-eluting stent implantation for the treatment of total coronary occlusions: rationale and design of the PRImary Stenting of Occluded Native coronary arteries III (PRISON III) study. | American heart journal 20070901 |
| A comparison of mortality, myocardial infarction, and repeated revascularization for sirolimus-eluting and paclitaxel-eluting coronary stents. | American heart journal 20070901 |
| Nonrandomized comparison of coronary stenting under intravascular ultrasound guidance of direct stenting without predilation versus conventional predilation with a semi-compliant balloon versus predilation with a new scoring balloon. | The American journal of cardiology 20070901 |
| Detailed intravascular ultrasound analysis of Zotarolimus-eluting phosphorylcholine-coated cobalt-chromium alloy stent in de novo coronary lesions (results from the ENDEAVOR II trial). | The American journal of cardiology 20070901 |
| Stent thrombosis after sirolimus- and paclitaxel-eluting stent implantation in daily clinical practice: analysis of a single center registry. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070901 |
| Sirolimus-eluting stent implantation for treatment of proximal left anterior descending coronary artery lesions: long-term outcome and predictors of adverse cardiac events. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070901 |
| Treatment options in renal cell carcinoma: past, present and future. | Annals of oncology : official journal of the European Society for Medical Oncology 20070901 |
| Phase I/II trial of temsirolimus combined with interferon alfa for advanced renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070901 |
| The combination of novel low molecular weight inhibitors of RAF (LBT613) and target of rapamycin (RAD001) decreases glioma proliferation and invasion. | Molecular cancer therapeutics 20070901 |
| Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle. | Cell metabolism 20070901 |
| Fatal Epstein-Barr virus-associated lymphoproliferative disorder following treatment with a novel mTOR inhibitor for relapsed chronic lymphocytic leukemia leukemia cells. | Haematologica 20070901 |
| Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070901 |
| Outlook of drug-eluting stent implantation for unprotected left main disease: insights on long-term clinical predictors. | The Journal of invasive cardiology 20070901 |
| Sirolimus-eluting stent thrombosis several years after clopidogrel discontinuation. | The Journal of invasive cardiology 20070901 |
| Sirolimus monotherapy as maintenance immunosuppression: single-center experience in 50 kidney transplant patients. | Transplantation proceedings 20070901 |
| mTOR inhibitors: do they help preserve renal function? | Transplantation proceedings 20070901 |
| Conversion from calcineurin inhibitors to sirolimus in kidney transplant patients reduces the urinary transforming growth factor-beta1 concentration. | Transplantation proceedings 20070901 |
| Pharmacogenetics of tacrolimus and sirolimus in renal transplant patients: from retrospective analyses to prospective studies. | Transplantation proceedings 20070901 |
| Evaluation of the efficacy and safety of the conversion from a calcineurin inhibitor to an everolimus-based therapy in maintenance renal transplant patients. | Transplantation proceedings 20070901 |
| Early sirolimus use with cyclosporine elimination does not induce progressive proteinuria. | Transplantation proceedings 20070901 |
| Use of the new proliferation signal inhibitor everolimus in renal transplant patients in Spain: preliminary results of the EVERODATA registry. | Transplantation proceedings 20070901 |
| Study of anemia after late introduction of everolimus in the immunosuppressive treatment of renal transplant patients. | Transplantation proceedings 20070901 |
| Conversion to sirolimus in posttransplant renal neoplasms. | Transplantation proceedings 20070901 |
| mTOR inhibitors and their secondary effects in cardiac transplant recipients: a descriptive study. | Transplantation proceedings 20070901 |
| Impact on renal function of the use of sirolimus in cardiac transplantation. | Transplantation proceedings 20070901 |
| Sirolimus in renal transplantation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070901 |
| Sirolimus for visceral and cutaneous Kaposi's sarcoma in a renal-transplant recipient. | Clinical and experimental nephrology 20070901 |
| New techniques and developments of stenting for infrainguinal arterial occlusive disease: are the results any better than balloon angioplasty alone? | Perspectives in vascular surgery and endovascular therapy 20070901 |
| [Relationship between plasma C-reactive protein level and neointimal hyperplasia volume in patients with zotarolimus-eluting stents. Volumetric analysis by three-dimensional intracoronary ultrasound]. | Revista espanola de cardiologia 20070901 |
| Sunitinib, sorafenib and mTOR inhibitors in renal cancer. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20070901 |
| Etanercept therapy for severe plaque psoriasis in a patient who underwent a liver transplant. | Cutis 20070901 |
| Metastatic renal cell carcinoma: role of mammalian target of rapamycin inhibitors. | Clinical genitourinary cancer 20070901 |
| Potential histologic and molecular predictors of response to temsirolimus in patients with advanced renal cell carcinoma. | Clinical genitourinary cancer 20070901 |
| [3/3 Inhibitors of mTOR (sirolimus and everolimus)]. | Soins; la revue de reference infirmiere 20070901 |
| Drug-eluting stent implantation could be associated with long-term coronary endothelial dysfunction. | International heart journal 20070901 |
| Very late stent thrombosis in late stent malapposition after sirolimus-eluting stent implantation. | International heart journal 20070901 |
| Chemical control over protein-protein interactions: beyond inhibitors. | Combinatorial chemistry & high throughput screening 20070901 |
| siRNA screening of the kinome identifies ULK1 as a multidomain modulator of autophagy. | The Journal of biological chemistry 20070831 |
| Replacement of calcineurin-inhibitors with sirolimus as primary immunosuppression in stable cardiac transplant recipients. | Transplantation 20070827 |
| PRAS40 is a target for mammalian target of rapamycin complex 1 and is required for signaling downstream of this complex. | The Journal of biological chemistry 20070824 |
| Off-label use of drug-eluting stents. | JAMA 20070822 |
| Serial angioscopic evidence of incomplete neointimal coverage after sirolimus-eluting stent implantation: comparison with bare-metal stents. | Circulation 20070821 |
| An activated mTOR/p70S6K signaling pathway in esophageal squamous cell carcinoma cell lines and inhibition of the pathway by rapamycin and siRNA against mTOR. | Cancer letters 20070818 |
| Inhibition of mammalian target of rapamycin signaling by 2-(morpholin-1-yl)pyrimido[2,1-alpha]isoquinolin-4-one. | The Journal of biological chemistry 20070817 |
| Oncogenic tyrosine kinase NPM/ALK induces activation of the rapamycin-sensitive mTOR signaling pathway. | Oncogene 20070816 |
| Intravascular ultrasound parameters associated with stent thrombosis after drug-eluting stent deployment. | The American journal of cardiology 20070815 |
| Sequential quadruple immunosuppression including sirolimus in extended criteria and nonheartbeating donor kidney transplantation. | Transplantation 20070815 |
| Incidence and predictors of drug-eluting stent thrombosis during and after discontinuation of thienopyridine treatment. | Circulation 20070814 |
| Drug-eluting stents: dual antiplatelet therapy for every survivor? | Circulation 20070814 |
| The effects of mTOR-Akt interactions on anti-apoptotic signaling in vascular endothelial cells. | The Journal of biological chemistry 20070810 |
| Risk factors for stent thrombosis after implantation of sirolimus-eluting stents in diabetic and nondiabetic patients: the EVASTENT Matched-Cohort Registry. | Journal of the American College of Cardiology 20070807 |
| [Lymphocele and kidney transplantation]. | Orvosi hetilap 20070805 |
| Structure of TOR and its complex with KOG1. | Molecular cell 20070803 |
| PI 3-K signaling pathway suppresses PMA-induced expression of p21WAF1/Cip1 in human leukemia cells. | Molecular and cellular biochemistry 20070801 |
| Snare extraction of a fractured coronary stent in a saphenous vein graft. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801 |
| Bifurcation stenting with a dedicated biolimus-eluting stent: X-ray visual enhancement of the final angiographic result with 'StentBoost Subtract'. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801 |
| Late drug-eluting stent thrombosis and erythropoietin: cause and effect? | Heart, lung & circulation 20070801 |
| Sirolimus and paclitaxel provoke different vascular pathological responses after local delivery in a murine model for restenosis on underlying atherosclerotic arteries. | Heart (British Cardiac Society) 20070801 |
| Influence of sirolimus on proteinuria in de novo kidney transplantation with expanded criteria donors: comparison of two CNI-free protocols. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801 |
| S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover. | American journal of physiology. Cell physiology 20070801 |
| Mammalian target of rapamycin: master regulator of cell growth in the nervous system. | Histology and histopathology 20070801 |
| Comparison between sirolimus- and paclitaxel-eluting stents in complex patient and lesions subsets. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801 |
| The Sirolimus-eluting coronary stent in daily routine practice in Germany: trends in indications over the years. Results from the prospective multi-centre German Cypher Stent Registry. | Clinical research in cardiology : official journal of the German Cardiac Society 20070801 |
| Myocardial ischaemia-reperfusion injury is attenuated by intact glucagon like peptide-1 (GLP-1) in the in vitro rat heart and may involve the p70s6K pathway. | Cardiovascular drugs and therapy 20070801 |
| Late-phase, protein synthesis-dependent long-term potentiation in hippocampal CA1 pyramidal neurones with destabilized microtubule networks. | British journal of pharmacology 20070801 |
| Renoprotective effects of sirolimus in non-immune initiated focal segmental glomerulosclerosis. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070801 |
| Combination of the oncolytic adenovirus ICOVIR-5 with chemotherapy provides enhanced anti-glioma effect in vivo. | Cancer gene therapy 20070801 |
| Long-term clinical benefit of sirolimus-eluting stent implantation in diabetic patients with de novo coronary stenoses: long-term results of the DIABETES trial. | European heart journal 20070801 |
| Phase 1 trial of everolimus and gefitinib in patients with advanced nonsmall-cell lung cancer. | Cancer 20070801 |
| The effect of sirolimus therapy on vaccine responses in transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070801 |
| Increased iNOS-expressing macrophage in long-term surviving rat small-bowel grafts. | American journal of surgery 20070801 |
| Three-year follow-up of the first prospective randomized comparison between paclitaxel and sirolimus stents: the TAXi-LATE trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801 |
| What kind of stent for you today and how would you like it prepared? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070801 |
| Tuberous sclerosis complex: advances in diagnosis, genetics, and management. | Journal of the American Academy of Dermatology 20070801 |
| Vascular pathology as a result of drug-eluting stents. | Heart (British Cardiac Society) 20070801 |
| Parallel stenting using two sirolimus-eluting stents in an ectatic coronary artery stenosis. | Heart (British Cardiac Society) 20070801 |
| Shared signaling networks active in B cells isolated from genetically distinct mouse models of lupus. | The Journal of clinical investigation 20070801 |
| Culotte versus T-stenting in bifurcation lesions: immediate clinical and angiographic results and midterm clinical follow-up. | American heart journal 20070801 |
| Neointimal progression and luminal narrowing in sirolimus-eluting stent treatment for bare metal in-stent restenosis: a quantitative intravascular ultrasound analysis. | American heart journal 20070801 |
| Drug-eluting stents vs bare metal stents for the treatment of large coronary vessels. | American heart journal 20070801 |
| External application of rapamycin-eluting film at anastomotic sites inhibits neointimal hyperplasia in a canine model. | The Annals of thoracic surgery 20070801 |
| Modulation of cholesterol homeostasis by antiproliferative drugs in human pterygium fibroblasts. | Investigative ophthalmology & visual science 20070801 |
| Predictors of target lesion revascularization and documented stent thrombosis beyond 30 days after sirolimus-eluting stent implantation: retrospective analysis in consecutive 1,070 angiographic follow-up lesions. | Circulation journal : official journal of the Japanese Circulation Society 20070801 |
| Comparison of six-month angiographic and three-year outcomes after sirolimus-eluting stent implantation versus brachytherapy for bare metal in-stent restenosis. | The American journal of cardiology 20070801 |
| Long-term clinical and angiographic outcomes of treatment of unprotected left main coronary artery stenosis with sirolimus-eluting stents. | The American journal of cardiology 20070801 |
| Monitoring biological action of rapamycin in renal transplantation. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20070801 |
| Analysis of programmed cell death in mouse fetal oocytes. | Reproduction (Cambridge, England) 20070801 |
| Direct stenting limits sirolimus-eluting stent edge neointimal thickening. | Journal of vascular surgery 20070801 |
| American Society of Clinical Oncology--43rd annual meeting. Translating research into practice. | IDrugs : the investigational drugs journal 20070801 |
| Rationale for a phase I trial of erlotinib and the mammalian target of rapamycin inhibitor everolimus (RAD001) for patients with relapsed non small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070801 |
| An improved bioluminescence resonance energy transfer strategy for imaging intracellular events in single cells and living subjects. | Cancer research 20070801 |
| [The relationship of mTOR signaling pathway and histone acetylation in human gastric cancer cell lines]. | Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics 20070801 |
| Sirolimus as primary immunosuppressant for calcineurin inhibitor-related renal insufficiency after liver transplantation. | Hepatobiliary & pancreatic diseases international : HBPD INT 20070801 |
| mTOR in tuberous sclerosis and other neurological disorders. | Epilepsia 20070801 |
| Akt-induced endocrine therapy resistance is reversed by inhibition of mTOR signaling. | Annals of oncology : official journal of the European Society for Medical Oncology 20070801 |
| Sirolimus-eluting versus bare-metal low-profile stent for renal artery treatment (GREAT Trial): angiographic follow-up after 6 months and clinical outcome up to 2 years. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20070801 |
| Rapamycin inhibits multiple stages of c-Neu/ErbB2 induced tumor progression in a transgenic mouse model of HER2-positive breast cancer. | Molecular cancer therapeutics 20070801 |
| Usefulness of drug eluting stent in percutaneous coronary intervention--a single center experience in Taiwan. | Journal of the Formosan Medical Association = Taiwan yi zhi 20070801 |
| Short- and long-term clinical outcomes of coronary drug-eluting stent recipients presenting with chronic renal disease. | The Journal of invasive cardiology 20070801 |
| Phase I trial of sirolimus combined with radiation and cisplatin in non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070801 |
| The biology behind mTOR inhibition in sarcoma. | The oncologist 20070801 |
| [Frequency and characteristics of incomplete stent apposition during and after sirolimus-eluting stent implantation]. | Journal of cardiology 20070801 |
| Economic analysis of the use of drug-eluting stents from the perspective of Belgian health care. | Acta cardiologica 20070801 |
| [Comparison of effects between China made sirolimus-eluting stents and bare stents for treating patients with acute myocardial infarction]. | Zhonghua xin xue guan bing za zhi 20070801 |
| Drug eluting stents: focus on Cypher sirolimus-eluting coronary stents in the treatment of patients with bifurcation lesions. | Vascular health and risk management 20070801 |
| Update on stents: recent studies on the TAXUS stent system in small vessels. | Vascular health and risk management 20070801 |
| Mechanisms of mammalian target of rapamycin inhibition in sarcoma: present and future. | Expert review of anticancer therapy 20070801 |
| Release profiles in drug-eluting stents: issues and uncertainties. | Journal of controlled release : official journal of the Controlled Release Society 20070731 |
| Human WIPI-1 puncta-formation: a novel assay to assess mammalian autophagy. | FEBS letters 20070724 |
| Increased late mortality after sirolimus-eluting stents versus bare-metal stents in diseased saphenous vein grafts: results from the randomized DELAYED RRISC Trial. | Journal of the American College of Cardiology 20070717 |
| 'Crying fire in a theater' or a 'confirmatory sighting?'. | Journal of the American College of Cardiology 20070717 |
| Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: a cohort analysis. | Blood 20070715 |
| BK virus-associated nephropathy in sirolimus-treated renal transplant patients: incidence, course, and clinical outcomes. | Transplantation 20070715 |
| RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070715 |
| Hypoxia-inducible factor 1alpha is regulated by the mammalian target of rapamycin (mTOR) via an mTOR signaling motif. | The Journal of biological chemistry 20070713 |
| Subacute stent thrombosis happening at discharge. | International journal of cardiology 20070710 |
| Two-year clinical follow-up after sirolimus-eluting versus bare-metal stent implantation assisted by systematic glycoprotein IIb/IIIa Inhibitor Infusion in patients with myocardial infarction: results from the STRATEGY study. | Journal of the American College of Cardiology 20070710 |
| Does the use of paclitaxel or rapamycin-eluting stent decrease further need for coronary-artery bypass grafting when compared with bare-metal stent? | Sao Paulo medical journal = Revista paulista de medicina 20070705 |
| Differential effects of the immunosuppressive agents cyclosporin A, tacrolimus and sirolimus on drug transport by multidrug resistance proteins. | Cancer chemotherapy and pharmacology 20070701 |
| Clinical impact of in-stent late loss after drug-eluting coronary stent implantation. | European heart journal 20070701 |
| Rapamycin together with herceptin significantly increased anti-tumor efficacy compared to either alone in ErbB2 over expressing breast cancer cells. | International journal of cancer 20070701 |
| Rapamycin retards growth and causes marked alterations in the growth plate of young rats. | Pediatric nephrology (Berlin, Germany) 20070701 |
| Isolated left pulmonary artery: interventional stenting of a persistent fifth aortic arch. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701 |
| Insulin potentiates Ca2+ signaling and phosphatidylinositol 4,5-bisphosphate hydrolysis induced by Gq protein-coupled receptor agonists through an mTOR-dependent pathway. | Endocrinology 20070701 |
| Rapamycin blunts nutrient stimulation of eIF4G, but not PKCepsilon phosphorylation, in skeletal muscle. | American journal of physiology. Endocrinology and metabolism 20070701 |
| Rapamycin prevents thyroid hormone-induced cardiac hypertrophy. | Endocrinology 20070701 |
| The effect of sirolimus- or cyclosporine-based immunosuppression effects on T-cell subsets in vivo. | Kidney international 20070701 |
| The acute phase protein alpha2-macroglobulin induces rat ventricular cardiomyocyte hypertrophy via ERK1,2 and PI3-kinase/Akt pathways. | Cardiovascular research 20070701 |
| Subclinical rejection and sirolimus associated edema in renal allograft recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20070701 |
| Transient sirolimus serum levels after implantation of a sirolimus eluting stent in an infant. | Clinical research in cardiology : official journal of the German Cardiac Society 20070701 |
| Mammalian target of rapamycin in the human placenta regulates leucine transport and is down-regulated in restricted fetal growth. | The Journal of physiology 20070701 |
| Vascular endothelial growth factor as a survival factor for human islets: effect of immunosuppressive drugs. | Diabetologia 20070701 |
| Removal of FKBP12/12.6 from endothelial ryanodine receptors leads to an intracellular calcium leak and endothelial dysfunction. | Arteriosclerosis, thrombosis, and vascular biology 20070701 |
| Rapamycin reduces CCR5 density levels on CD4 T cells, and this effect results in potentiation of enfuvirtide (T-20) against R5 strains of human immunodeficiency virus type 1 in vitro. | Antimicrobial agents and chemotherapy 20070701 |
| Vascular responses to drug eluting stents: importance of delayed healing. | Arteriosclerosis, thrombosis, and vascular biology 20070701 |
| Contrasting effects of cyclosporine and rapamycin in de novo generation of alloantigen-specific regulatory T cells. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070701 |
| Inhibition of endogenous MHC class II-restricted antigen presentation by tacrolimus (FK506) via FKBP51. | European journal of immunology 20070701 |
| The localization of nuclear exporters of the importin-beta family is regulated by Snf1 kinase, nutrient supply and stress. | Biochimica et biophysica acta 20070701 |
| Treatment of patients with advanced soft tissue sarcoma: disappointment or challenge? | Current opinion in oncology 20070701 |
| Insulin-like growth factor-I has different effects on myogenin induction and cell cycle progression in human alveolar and embryonal rhabdomyosarcoma cells. | International journal of oncology 20070701 |
| Molecular impacts of rapamycin-based drug combinations: combining rapamycin with gemcitabine or imatinib mesylate (Gleevec) in a human leiomyosarcoma model. | International journal of oncology 20070701 |
| Possible involvement of persistent activity of the mammalian target of rapamycin pathway in the cisplatin resistance of AFP-producing gastric cancer cells. | Cancer biology & therapy 20070701 |
| Confined late stent thrombosis following clopidogrel withdrawal in a patient with multi-segment sirolimus-eluting stent implants. | Journal of cardiovascular medicine (Hagerstown, Md.) 20070701 |
| Tumour-derived fibroblast growth factor-2 exerts lymphangiogenic effects through Akt/mTOR/p70S6kinase pathway in rat lymphatic endothelial cells. | European journal of cancer (Oxford, England : 1990) 20070701 |
| One pathway, many products. | Nature chemical biology 20070701 |
| Risk of stent thrombosis after sirolimus or paclitaxel eluting coronary stent implantation. | British journal of clinical pharmacology 20070701 |
| Revascularization for ischemic LV dysfunction: stents or surgery? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701 |
| Comparison of drug-eluting stents with bare metal stents in unselected patients with acute myocardial infarction. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701 |
| Treatment of drug-eluting stent restenosis with the same versus different drug-eluting stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701 |
| Two-by-two factorial comparison of high-bolus-dose tirofiban followed by standard infusion versus abciximab and sirolimus-eluting versus bare-metal stent implantation in patients with acute myocardial infarction: design and rationale for the MULTI-STRATEGY trial. | American heart journal 20070701 |
| Sirolimus-eluting stents compared with standard stents in the treatment of patients with primary angioplasty. | American heart journal 20070701 |
| Revascularization in severe left ventricular dysfunction: outcome comparison of drug-eluting stent implantation versus coronary artery by-pass grafting. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701 |
| Modified T-stenting with intentional protrusion of the side-branch stent within the main vessel stent to ensure ostial coverage and facilitate final kissing balloon: the T-stenting and small protrusion technique (TAP-stenting). Report of bench testing and first clinical Italian-Korean two-centre experience. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070701 |
| The role of mTOR inhibitors for treatment of sarcomas. | Current oncology reports 20070701 |
| Uneventful thoracic healing with everolimus after aortic valve replacement. | The Annals of thoracic surgery 20070701 |
| Therapeutics of vein graft intimal hyperplasia: 100 years on. | The Annals of thoracic surgery 20070701 |
| Duration of clopidogrel therapy after placement of drug-eluting intracoronary stent. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070701 |
| Late restenosis following sirolimus-eluting stent implantation. | The American journal of cardiology 20070701 |
| Long-term clinical outcomes and thrombosis rates of sirolimus-eluting versus paclitaxel-eluting stents in an unselected population with coronary artery disease (REWARDS registry). | The American journal of cardiology 20070701 |
| Intravascular ultrasound comparison of sirolimus-eluting stent versus bare metal stent implantation in diseased saphenous vein grafts (from the RRISC [Reduction of Restenosis In Saphenous Vein Grafts With Cypher Sirolimus-Eluting Stent] trial). | The American journal of cardiology 20070701 |
| Combined therapeutic effects of vinblastine and rapamycin on human neuroblastoma growth, apoptosis, and angiogenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070701 |
| Interleukin-17 and airway inflammation: a longitudinal airway biopsy study after lung transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070701 |
| Observational study with everolimus (Certican) in combination with low-dose cyclosporine in de novo heart transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070701 |
| Bronchial and peripheral murine lung carcinomas induced by T790M-L858R mutant EGFR respond to HKI-272 and rapamycin combination therapy. | Cancer cell 20070701 |
| Angiographic and histological assessment of successfully treated late acute stent thrombosis secondary to a sirolimus-eluting stent. | European heart journal 20070701 |
| Sensitizing HER2-overexpressing cancer cells to luteolin-induced apoptosis through suppressing p21(WAF1/CIP1) expression with rapamycin. | Molecular cancer therapeutics 20070701 |
| The influence of low (81 mg) versus high (325 mg) doses of ASA on the incidence of sirolimus-eluting stent thrombosis. | The Journal of invasive cardiology 20070701 |
| A three-dimensional intravascular ultrasound comparison between the new zotarolimus-eluting stent (ZoMaxx) and the non-drug-eluting TriMaxx stent. | The Journal of invasive cardiology 20070701 |
| Temsirolimus in the treatment of advanced renal cell carcinoma. | Annals of oncology : official journal of the European Society for Medical Oncology 20070701 |
| Sirolimus toxicity and vascular endothelial growth factor release from islet and renal cell lines. | Transplantation 20070627 |
| Long-term safety and efficacy of drug-eluting stents: two-year results of the REAL (REgistro AngiopLastiche dell'Emilia Romagna) multicenter registry. | Circulation 20070626 |
| Stress-responsive Gln3 localization in Saccharomyces cerevisiae is separable from and can overwhelm nitrogen source regulation. | The Journal of biological chemistry 20070622 |
| [Present circumstance around percutaneous coronary intervention (PCI): before and after drug eluting stent (DES) introduction]. | Nihon Hoshasen Gijutsu Gakkai zasshi 20070620 |
| Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis. | Journal of the American College of Cardiology 20070619 |
| Comparable clinical outcomes with paclitaxel- and sirolimus-eluting stents in unrestricted contemporary practice. | Journal of the American College of Cardiology 20070619 |
| Phosphorylation of ribosomal p70 S6 kinase and rapamycin sensitivity in human colorectal cancer. | Cancer letters 20070618 |
| Bystin in human cancer cells: intracellular localization and function in ribosome biogenesis. | The Biochemical journal 20070615 |
| Six-month clinical and angiographic results of a dedicated drug-eluting stent for the treatment of coronary bifurcation narrowings. | The American journal of cardiology 20070615 |
| The effects of granulocyte-colony stimulating factor in bare stent and sirolimus-eluting stent in pigs following myocardial infarction. | International journal of cardiology 20070612 |
| Drug eluting stent implantation for the treatment of symptomatic myocardial bridging is associated with favorable peri-procedural results and short-term outcomes. | International journal of cardiology 20070612 |
| Sch9 is a major target of TORC1 in Saccharomyces cerevisiae. | Molecular cell 20070608 |
| Sirolimus-induced posterior reversible encephalopathy. | Neurology 20070605 |
| Coronary artery stent fracture. | The international journal of cardiovascular imaging 20070601 |
| Stent fracture: an unusual cause of late restenosis after sirolimus-eluting stent placement. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070601 |
| Target lesion revascularisation in patients treated with a sirolimus-eluting or paclitaxel-eluting stent. | Heart (British Cardiac Society) 20070601 |
| The rapid activation of protein synthesis by growth hormone requires signaling through mTOR. | American journal of physiology. Endocrinology and metabolism 20070601 |
| Long-term outcomes of bifurcation lesions after implantation of drug-eluting stents with the 'mini-crush technique'. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070601 |
| Identification and characterization of a functional Candida albicans homolog of the Saccharomyces cerevisiae TCO89 gene. | FEMS yeast research 20070601 |
| Anti-atherosclerotic effects of sirolimus on human vascular smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20070601 |
| The Mammalian target of rapamycin pathway regulates nutrient-sensitive glucose uptake in man. | Diabetes 20070601 |
| Caerulein-induced intracellular pancreatic zymogen activation is dependent on calcineurin. | American journal of physiology. Gastrointestinal and liver physiology 20070601 |
| Rapamycin-induced hypokalaemic nephropathy in a middle-aged hypertensive male. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070601 |
| Late experimental amebic liver abscess in hamster is inhibited by cyclosporine and N-acetylcysteine. | Experimental and molecular pathology 20070601 |
| An antibody delivery system for regulated expression of therapeutic levels of monoclonal antibodies in vivo. | Molecular therapy : the journal of the American Society of Gene Therapy 20070601 |
| Rapamycin stimulates arginine influx through CAT2 transporters in human endothelial cells. | Biochimica et biophysica acta 20070601 |
| Comparison of the CEDIA and MEIA assays for the measurement of sirolimus in organ transplant recipients. | Clinical biochemistry 20070601 |
| Physiologically based pharmacokinetic (PBPK) modeling of everolimus (RAD001) in rats involving non-linear tissue uptake. | Journal of pharmacokinetics and pharmacodynamics 20070601 |
| The influence of cyclosporin A on lymphocyte attenuator expression. | Journal of autoimmunity 20070601 |
| mTOR-inhibitors simultaneously inhibit proliferation and basal IL-6 synthesis of human coronary artery endothelial cells. | International immunopharmacology 20070601 |
| Late incomplete apposition after drug-eluting stent implantation: incidence and potential for adverse clinical outcomes. | European heart journal 20070601 |
| Small molecules enhance autophagy and reduce toxicity in Huntington's disease models. | Nature chemical biology 20070601 |
| Is there delayed restenosis in patients with coronary artery disease treated with sirolimus-eluting stent? | Coronary artery disease 20070601 |
| Severe intimal hyperplasia after sirolimus eluting stent deployment: evaluation by optical coherence tomography. | Heart (British Cardiac Society) 20070601 |
| Stimulating the cell's appetite for itself. | Nature chemical biology 20070601 |
| Assessment and validation of the MS/MS fragmentation patterns of the macrolide immunosuppressant everolimus. | Journal of mass spectrometry : JMS 20070601 |
| Antigenic disparity impacts outcome of agonism but not blockade of costimulatory pathways in experimental transplant models. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070601 |
| Early withdrawal of calcineurin inhibitors and rescue immunosuppression with sirolimus-based therapy in renal transplant recipients with moderate to severe renal dysfunction. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070601 |
| Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T cells, but enrich for antigen-specific Foxp3+ T regulatory cells and promote organ transplant tolerance. | Journal of immunology (Baltimore, Md. : 1950) 20070601 |
| Compared effect of immunosuppressive drugs cyclosporine A and rapamycin on cholesterol homeostasis key enzymes CYP27A1 and HMG-CoA reductase. | Basic & clinical pharmacology & toxicology 20070601 |
| Stent fracture-unusual cause of DES restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070601 |
| Sirolimus as part of immunosuppressive therapy for refractory chronic graft-versus-host disease. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20070601 |
| Sirolimus-induced pneumonitis following liver transplantation. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20070601 |
| Subclavian-vertebral artery bifurcation stenting using drug-eluting stents: a report of two cases using different techniques. | The Journal of invasive cardiology 20070601 |
| Prevention of acute rejection and allograft vasculopathy by everolimus in cardiac transplants recipients: a 24-month analysis. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601 |
| Low-dose tacrolimus/sirolimus and steroid withdrawal in heart recipients is highly efficacious. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601 |
| Sirolimus-induced alveolar hemorrhage. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601 |
| Possible everolimus-induced, severe, reversible encephalopathy after cardiac transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070601 |
| Endothelial Akt signaling is rate-limiting for rapamycin inhibition of mouse mammary tumor progression. | Cancer research 20070601 |
| Comparative characterization of cellular and molecular anti-restenotic profiles of paclitaxel and sirolimus. Implications for local drug delivery. | Thrombosis and haemostasis 20070601 |
| Sirolimus and liver transplantation: clinical implications for hepatocellular carcinoma. | Expert opinion on pharmacotherapy 20070601 |
| Is sirolimus a nephrotoxic drug? A report of five cases. | Transplantation proceedings 20070601 |
| Protective effects of sirolimus by attenuating connective tissue growth factor expression in human chronic allograft nephropathy. | Transplantation proceedings 20070601 |
| Lack of hepatotoxicity upon sirolimus addition to a calcineurin inhibitor-based regimen in hepatitis virus-positive renal transplant recipients. | Transplantation proceedings 20070601 |
| Rejection episodes and 3-year graft survival under sirolimus and tacrolimus treatment after adult intestinal transplantation. | Transplantation proceedings 20070601 |
| Comparison of stent graft, sirolimus stent, and bare metal stent implanted in patients with acute coronary syndrome: clinical and angiographic follow-up. | Croatian medical journal 20070601 |
| Formulation of sirolimus eye drops and corneal permeation studies. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20070601 |
| Progressive multifocal leukoencephalopathy: a case study. | Progress in transplantation (Aliso Viejo, Calif.) 20070601 |
| Use and long-term outcome of bare metal stent implantation in the drug-eluting stent era. | Journal of cardiology 20070601 |
| Impact of highly asymmetric stent expansion after sirolimus-eluting stent implantation on twelve-month clinical outcomes. | Journal of cardiology 20070601 |
| [Limitation on efficacy of sirolimus-eluting stent implantation in patients on hemodialysis]. | Journal of cardiology 20070601 |
| Restenosis developing over one year after implantation with a sirolimus-eluting stent: two case reports. | Journal of cardiology 20070601 |
| Rational use of drug-eluting stents: a comparison of different policies. | Critical pathways in cardiology 20070601 |
| [Pilot study of a cell membrane like biomimetic drug-eluting coronary stent]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20070601 |
| Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. | The New England journal of medicine 20070531 |
| Long-term renal transplant function in recipient of simultaneous kidney and pancreas transplant maintained with two prednisone-free maintenance immunosuppressive combinations: tacrolimus/mycophenolate mofetil versus tacrolimus/sirolimus. | Transplantation 20070527 |
| Sirolimus conversion in liver transplant recipients with renal dysfunction: a prospective, randomized, single-center trial. | Transplantation 20070527 |
| Firebird sirolimus eluting stent versus bare mental stent in patients with ST-segment elevation myocardial infarction. | Chinese medical journal 20070520 |
| Sirolimus eluting stent fracture following angioplasty of diffuse in-stent restenosis in the right coronary artery. | International journal of cardiology 20070516 |
| Complete fracture of sirolimus-eluting stent detected by multislice computed tomography. | International journal of cardiology 20070516 |
| Overlapping hybrid stenting with a sirolimus-eluting stent and a bare metal stent. | International journal of cardiology 20070516 |
| Engineering small molecule specificity in nearly identical cellular environments. | Bioorganic & medicinal chemistry letters 20070515 |
| Meta-analysis of randomized trials of drug-eluting stents versus bare metal stents in patients with diabetes mellitus. | The American journal of cardiology 20070515 |
| Percutaneous coronary revascularization using a trilayer metal phosphorylcholine-coated zotarolimus-eluting stent. | The American journal of cardiology 20070515 |
| De novo sirolimus-based immunosuppression after liver transplantation for hepatocellular carcinoma: long-term outcomes and side effects. | Transplantation 20070515 |
| CD154 blockade, sirolimus, and donor-specific transfusion prevents renal allograft rejection in cynomolgus monkeys despite homeostatic T-cell activation. | Transplantation 20070515 |
| Late introduction of sirolimus induces anemia in renal transplant recipients. | Transplantation 20070515 |
| Randomized trial of Sirolimus-Eluting Stent Versus Bare-Metal Stent in Acute Myocardial Infarction (SESAMI). | Journal of the American College of Cardiology 20070515 |
| Drug-eluting stents for acute myocardial infarction. | Journal of the American College of Cardiology 20070515 |
| Outcomes and complications associated with off-label and untested use of drug-eluting stents. | JAMA 20070509 |
| Clinical outcomes and stent thrombosis following off-label use of drug-eluting stents. | JAMA 20070509 |
| The enigma of drug-eluting stents: hope, hype, humility, and advancing patient care. | JAMA 20070509 |
| Pathological correlates of late drug-eluting stent thrombosis: strut coverage as a marker of endothelialization. | Circulation 20070508 |
| What to do about late incomplete stent apposition? | Circulation 20070508 |
| Incomplete stent apposition and very late stent thrombosis after drug-eluting stent implantation. | Circulation 20070508 |
| The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain. | The Journal of biological chemistry 20070504 |
| CYPHER versus TAXUS stent for bifurcation lesions beyond 30 days-long-term follow-up results. | International journal of cardiology 20070502 |
| Longitudinal inhibition of PI3K/Akt/mTOR signaling by LY294002 and rapamycin induces growth arrest of adult T-cell leukemia cells. | Leukemia research 20070501 |
| Calcineurin-independent inhibition of KV1.3 by FK-506 (tacrolimus): a novel pharmacological property. | American journal of physiology. Cell physiology 20070501 |
| Impact of renal insufficiency on clinical and angiographic outcomes following percutaneous coronary intervention with sirolimus-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501 |
| Factors predictive of cardiac events and restenosis after sirolimus-eluting stent implantation in small coronary arteries. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501 |
| Diagnosis of de novo localized thrombotic microangiopathy by surveillance biopsy. | Pediatric nephrology (Berlin, Germany) 20070501 |
| Simultaneous LC-MS-MS determination of cyclosporine A, tacrolimus, and sirolimus in whole blood as well as mycophenolic acid in plasma using common pretreatment procedure. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501 |
| Rapamycin-regulated control of antiangiogenic tumor therapy following rAAV-mediated gene transfer. | Molecular therapy : the journal of the American Society of Gene Therapy 20070501 |
| Kidney function after islet transplant alone in type 1 diabetes: impact of immunosuppressive therapy on progression of diabetic nephropathy. | Diabetes care 20070501 |
| Randomized comparative trial of a thin-strut bare metal cobalt-chromium stent versus a sirolimus-eluting stent for coronary revascularization. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501 |
| Sirolimus-eluting biodegradable poly-L-lactide stent for peripheral vascular application: a preliminary study in porcine carotid arteries. | The Journal of surgical research 20070501 |
| Comparison of fluorescent polarization immunoassay (FPIA) versus HPLC to measure everolimus blood concentrations in clinical transplantation. | Clinica chimica acta; international journal of clinical chemistry 20070501 |
| Vascular remodeling and antitumoral effects of mTOR inhibition in a rat model of hepatocellular carcinoma. | Journal of hepatology 20070501 |
| Incidence and predictors of target vessel revascularization after sirolimus-eluting stent treatment for proximal left anterior descending artery stenoses among 2274 patients from the prospective multicenter German Cypher Stent Registry. | Clinical research in cardiology : official journal of the German Cardiac Society 20070501 |
| Rapamycin, not cyclosporine, permits thymic generation and peripheral preservation of CD4+ CD25+ FoxP3+ T cells. | Bone marrow transplantation 20070501 |
| The role of proliferation signal inhibitors in post-transplant malignancies. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501 |
| Restenosis following thin-strut bare-metal stents versus thick-strut drug-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501 |
| Posterior reversible encephalopathy syndrome due to sirolimus. | Bone marrow transplantation 20070501 |
| Sirolimus impairs wound healing. | Langenbeck's archives of surgery 20070501 |
| Stent thrombosis with drug-eluting stents: a re-examination of the evidence. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070501 |
| An in vitro cytologic assay for evaluation of the KIT signaling pathway in gastrointestinal stromal tumors. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20070501 |
| Rapamycin, a specific inhibitor of the mammalian target of rapamycin, suppresses lymphangiogenesis and lymphatic metastasis. | Cancer science 20070501 |
| Influence of the UGT2B7 promoter region and exon 2 polymorphisms and comedications on Acyl-MPAG production in vitro and in adult renal transplant patients. | Pharmacogenetics and genomics 20070501 |
| Reversal of loss of glomerular filtration rate in children with transplant nephropathy after switch to everolimus and low-dose cyclosporine A. | Pediatric transplantation 20070501 |
| Reversal of tacrolimus-related hypertrophic cardiomyopathy after conversion to rapamycin in a pediatric liver transplant recipient. | Pediatric transplantation 20070501 |
| Sirolimus is not always responsible for new-onset proteinuria after conversion for chronic allograft nephropathy. | Pediatric transplantation 20070501 |
| Therapeutic effect of a new immunosuppressive agent, everolimus, on interleukin-10 gene-deficient mice with colitis. | Clinical and experimental immunology 20070501 |
| Calcineurin inhibitors and rapamycin: cancer protection or promotion? | Experimental dermatology 20070501 |
| mTOR as a potential therapeutic target for treatment of keloids and excessive scars. | Experimental dermatology 20070501 |
| Meta-analysis of clinical trials on use of drug-eluting stents for treatment of acute myocardial infarction. | American heart journal 20070501 |
| Pretransplant HLA antibodies are associated with reduced graft survival after clinical islet transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070501 |
| Kaposi's sarcoma in renal transplant recipients--the impact of proliferation signal inhibitors. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501 |
| Use of proliferation signal inhibitors in non-melanoma skin cancer following renal transplantation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501 |
| Post-transplant lymphoproliferative disorder--the potential of proliferation signal inhibitors. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501 |
| Use of proliferation signal inhibitors in the management of post-transplant malignancies--clinical guidance. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501 |
| Conversion to sirolimus-based immunosuppression in maintenance liver transplantation patients. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20070501 |
| Costimulation blockade--what will the future bring? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070501 |
| Do the results of the new trials change the standard treatment of metastatic renal cell cancer? | Onkologie 20070501 |
| Sirolimus treatment for pulmonary lymphangioleiomyomatosis. | Annals of internal medicine 20070501 |
| Uncertainty. | Nature clinical practice. Gastroenterology & hepatology 20070501 |
| Impact of the Food and Drug Administration's Public Health Notification on the adoption of drug-eluting stents. | The American journal of cardiology 20070501 |
| The Akt/mammalian target of rapamycin signal transduction pathway is activated in high-risk myelodysplastic syndromes and influences cell survival and proliferation. | Cancer research 20070501 |
| Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth. | Cancer research 20070501 |
| Targeted therapies for soft-tissue sarcomas. | Expert review of anticancer therapy 20070501 |
| A pharmacokinetic interaction between clarithromycin and sirolimus in kidney transplant recipient. | Current drug metabolism 20070501 |
| Effect of rapamycin on wound healing: an experimental study. | Transplantation proceedings 20070501 |
| An assay for the determination of sirolimus levels in the lymphocyte of transplant patients. | Transplantation proceedings 20070501 |
| Lymphedema: an unusual complication of sirolimus therapy. | Transplantation proceedings 20070501 |
| Optimization of immunosuppressive drug monitoring in children. | Transplantation proceedings 20070501 |
| Complete regression of cutaneous B-cell lymphoma in a renal transplant patient after conversion from cyclosporin to sirolimus. | Transplantation proceedings 20070501 |
| Retinal injury as an early manifestation of posttransplant thrombotic microangiopathy: recovery with plasma exchanges and conversion to sirolimus--case report and review of the literature. | Transplantation proceedings 20070501 |
| Stent fracture and restenosis after placement of a drug-eluting device in the vertebral artery origin and treatment with the stent-in-stent technique. Report of two cases. | Journal of neurosurgery 20070501 |
| Conversion to combined therapy with sirolimus and mycophenolate mofetil improved renal function in stable renal transplant recipients. | Journal of the Formosan Medical Association = Taiwan yi zhi 20070501 |
| Sirolimus-eluting stents in real-world patients with ST-segment elevation acute myocardial infarction. | International heart journal 20070501 |
| Two cases of very late stent thrombosis after implantation of a sirolimus-eluting stent presenting as AMI. | International heart journal 20070501 |
| [Angioplasty stenting with Sirolimus (rapamycin) eluting stents in type 2 diabetic patients]. | Revista medica de Chile 20070501 |
| Clinical development of mTOR inhibitors: a focus on lymphoma. | Reviews on recent clinical trials 20070501 |
| Rapamycin enhances the number of alloantigen-induced human CD103+CD8+ regulatory T cells in vitro. | Transplantation 20070427 |
| Rapamycin inhibits proliferation of Epstein-Barr virus-positive B-cell lymphomas through modulation of cell-cycle protein expression. | Transplantation 20070427 |
| Regulation of survivin expression by IGF-1/mTOR signaling. | Oncogene 20070426 |
| Clopidogrel and long-term outcomes after drug-eluting stent implantation. | JAMA 20070425 |
| Clopidogrel and long-term outcomes after drug-eluting stent implantation. | JAMA 20070425 |
| Clopidogrel and long-term outcomes after drug-eluting stent implantation. | JAMA 20070425 |
| Clopidogrel and long-term outcomes after drug-eluting stent implantation. | JAMA 20070425 |
| [Late stent thrombosis with drug eluting stents: disturbing signals on the radar]. | Ugeskrift for laeger 20070423 |
| p21-activated kinase 1 is activated through the mammalian target of rapamycin/p70 S6 kinase pathway and regulates the replication of hepatitis C virus in human hepatoma cells. | The Journal of biological chemistry 20070420 |
| Distinct EBV and CMV reactivation patterns following antibody-based immunosuppressive regimens in patients with severe aplastic anemia. | Blood 20070415 |
| Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML. | Blood 20070415 |
| Mammalian target of rapamycin is activated in human gastric cancer and serves as a target for therapy in an experimental model. | International journal of cancer 20070415 |
| PI3K(p110alpha) inhibitors as anti-cancer agents: minding the heart. | Cell cycle (Georgetown, Tex.) 20070415 |
| Comparison of three-year clinical outcome of sirolimus- and paclitaxel-eluting stents versus bare metal stents in patients with ST-segment elevation myocardial infarction (from the RESEARCH and T-SEARCH Registries). | The American journal of cardiology 20070415 |
| Evaluation by optical coherence tomography of neointimal coverage of sirolimus-eluting stent three months after implantation. | The American journal of cardiology 20070415 |
| Analysis of 36 reported cases of late thrombosis in drug-eluting stents placed in coronary arteries. | The American journal of cardiology 20070415 |
| Safety of sirolimus-eluting stenting and its effect on restenosis in patients with unstable angina pectoris (a SIRIUS substudy). | The American journal of cardiology 20070415 |
| Cyphering the complexity of coronary artery disease using the syntax score to predict clinical outcome in patients with three-vessel lumen obstruction undergoing percutaneous coronary intervention. | The American journal of cardiology 20070415 |
| Therapeutic effect of rapamycin on gallbladder cancer in a transgenic mouse model. | Cancer research 20070415 |
| Kidney transplantation with sirolimus and mycophenolate mofetil-based immunosuppression: 5-year results of a randomized prospective trial compared to calcineurin inhibitor drugs. | Transplantation 20070415 |
| Sirolimus-eluting stent showed better one-year outcomes than paclitaxel-eluting stent in a real life setting of coronary intervention in Koreans. | International journal of cardiology 20070412 |
| AKT activity regulates the ability of mTOR inhibitors to prevent angiogenesis and VEGF expression in multiple myeloma cells. | Oncogene 20070405 |
| Late stent thrombosis: a not negligible issue after drug-eluting stent implantation. | Chinese medical journal 20070405 |
| Sirolimus-eluting cobalt alloyed stents in treating patients with coronary artery disease: six-month angiographic and one-year clinical follow-up result. A prospective, historically controlled, multi-center clinical study. | Chinese medical journal 20070405 |
| Long-term outcomes following drug-eluting stent implantation in unprotected left main bifurcation lesions. | Chinese medical journal 20070405 |
| Drug-eluting stent for the treatment of small coronary lesion: comparison between sirolimus- and paclitaxel-eluting stent. | Chinese medical journal 20070405 |
| A comparison of clinical and angiographic outcomes after Excel bioabsorbable polymer versus Firebird durable polymer rapamycin-eluting stent for the treatment of coronary artery disease in a 'real world' setting: six-month follow-up results. | Chinese medical journal 20070405 |
| Type-D personality predicts chronic anxiety following percutaneous coronary intervention in the drug-eluting stent era. | Journal of affective disorders 20070401 |
| A HPLC-mass spectrometric method suitable for the therapeutic drug monitoring of everolimus. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070401 |
| Neointimal coverage of sirolimus-eluting stents at 6-month follow-up: evaluated by optical coherence tomography. | European heart journal 20070401 |
| Extended follow-up of methotrexate-free immunosuppression using sirolimus and tacrolimus in related and unrelated donor peripheral blood stem cell transplantation. | Blood 20070401 |
| Mechanism of apoptosis induced by IFN-alpha in human myeloma cells: role of Jak1 and Bim and potentiation by rapamycin. | Cellular signalling 20070401 |
| A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling. | The Biochemical journal 20070401 |
| Rapamycin is a neuroprotective treatment for traumatic brain injury. | Neurobiology of disease 20070401 |
| Rapamycin: brain excitability studied in vitro. | Epilepsia 20070401 |
| Ssh4, Rcr2 and Rcr1 affect plasma membrane transporter activity in Saccharomyces cerevisiae. | Genetics 20070401 |
| Chronic alcohol consumption alters mammalian target of rapamycin (mTOR), reduces ribosomal p70s6 kinase and p4E-BP1 levels in mouse cerebral cortex. | Experimental neurology 20070401 |
| Accurate determination of an immunosuppressant in stented swine tissues with LC-MS/MS. | Analytical and bioanalytical chemistry 20070401 |
| Inhibition of the mammalian target of rapamycin impedes lymphangiogenesis. | Kidney international 20070401 |
| Mutasynthesis - uniting chemistry and genetics for drug discovery. | Trends in biotechnology 20070401 |
| Gonadal impact of target of rapamycin inhibitors (sirolimus and everolimus) in male patients: an overview. | Transplant international : official journal of the European Society for Organ Transplantation 20070401 |
| Hemolytic uremic syndrome following Campath-1H induction. | Transplant international : official journal of the European Society for Organ Transplantation 20070401 |
| No recurrence of Kaposi's sarcoma in a case of renal retransplantation under a calcineurin inhibitor free immunosuppressive regimen: first report. | Transplant international : official journal of the European Society for Organ Transplantation 20070401 |
| Differential modulation of mitogen driven proliferation and homeostasis driven proliferation of T cells by rapamycin, Ly294002 and chlorophyllin. | Molecular immunology 20070401 |
| The effect of immunosuppressive drug rapamycin on regulatory CD4+CD25+Foxp3+T cells in mice. | Transplant immunology 20070401 |
| Rapamycin inhibits cell growth by induction of apoptosis on hepatocellular carcinoma cells in vitro. | Transplant immunology 20070401 |
| Effect of sirolimus treatment on gene expression in renal transplant patients. | World journal of surgery 20070401 |
| PI3K/AKT/mTOR hypersignaling in autoimmune lymphoproliferative disease engendered by the epistatic interplay of Sle1b and FASlpr. | International immunology 20070401 |
| Limitation by p70 S6 kinase of platelet-derived growth factor-BB-induced interleukin 6 synthesis in osteoblast-like MC3T3-E1 cells. | Metabolism: clinical and experimental 20070401 |
| Drug-eluting stent-induced left anterior descending coronary artery aneurysm: repair by pericardial patch--where are we headed? | The Annals of thoracic surgery 20070401 |
| Incidence of side-effects of ticlopidine after sirolimus-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20070401 |
| Effects of immunosuppressive drugs on in vitro neogenesis of human islets: mycophenolate mofetil inhibits the proliferation of ductal cells. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070401 |
| Diabetic retinopathy and coronary implantation of sirolimus-eluting stents. | Journal of interventional cardiology 20070401 |
| Potential therapeutic applications of autophagy. | Nature reviews. Drug discovery 20070401 |
| Recommendations for the use of everolimus (Certican) in heart transplantation: results from the second German-Austrian Certican Consensus Conference. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070401 |
| Identification of a highly effective rapamycin schedule that markedly reduces the size, multiplicity, and phenotypic progression of tobacco carcinogen-induced murine lung tumors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070401 |
| Comparison of vessel response following sirolimus-eluting stent implantation as assessed by serial 3-D intravascular ultrasound study. | The Journal of invasive cardiology 20070401 |
| Sirolimus-eluting stents for the treatment of bare-metal in-stent restenosis: long-term clinical follow up. | The Journal of invasive cardiology 20070401 |
| Late stent thrombosis associated with coronary aneurysm formation after sirolimus-eluting stent implantation. | The Journal of invasive cardiology 20070401 |
| Activation of mitogen-activated protein kinase by hepatocyte growth factor is stimulated by both alpha1- and beta2-adrenergic agonists in primary cultures of adult rat hepatocytes. | Journal of pharmacological sciences 20070401 |
| [Effect of Rapamycin on CD4(+) CD25(+) regulatory T cells in allo-transplantation tolerance model]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20070401 |
| How to control lymphangiogenesis: a novel role for rapamycin. | Kidney international 20070401 |
| [Induction effect of rapamycin combined paclitaxel on apoptosis of ovarian cancer cell lines A2780 and SKOV3 and the molecular mechanism]. | Ai zheng = Aizheng = Chinese journal of cancer 20070401 |
| Drug-eluting stents show delayed healing: paclitaxel more pronounced than sirolimus. | European heart journal 20070401 |
| Zotarolimus, a novel sirolimus analogue with potent anti-proliferative activity on coronary smooth muscle cells and reduced potential for systemic immunosuppression. | Journal of cardiovascular pharmacology 20070401 |
| Conversion from a calcineurin inhibitor-based immunosuppressive regimen to everolimus in renal transplant recipients: effect on renal function and proteinuria. | Transplantation proceedings 20070401 |
| Case report of a kidney transplant recipient converted to everolimus due to malignancy: resolution of bronchiolitis obliterans organizing pneumonia without everolimus discontinuation. | Transplantation proceedings 20070401 |
| Sirolimus-eluting versus bare stents after suboptimal infrapopliteal angioplasty for critical limb ischemia: enduring 1-year angiographic and clinical benefit. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20070401 |
| Participation of phosphatidyl inositol 3-kinase/protein kinase B and ERK1/2 pathways in interleukin-1beta stimulation of lactate production in Sertoli cells. | Reproduction (Cambridge, England) 20070401 |
| Cost-effectiveness of sirolimus-eluting stents in percutaneous coronary interventions in Brazil. | Arquivos brasileiros de cardiologia 20070401 |
| Sirolimus-eluting coronary stents: a review. | Vascular health and risk management 20070401 |
| [Procedural success and 10-month outcome between Cypher and TAXUS drug-eluting stents for the treatment of in-stent restenosis]. | Zhonghua xin xue guan bing za zhi 20070401 |
| [Very late stent thrombosis after implantation of sirolimus eluting coronary stents]. | Zhonghua xin xue guan bing za zhi 20070401 |
| [Re-occurred acute myocardial infarction caused by very late thrombosis 36 months after implantation of sirolimus eluting stent: a case report]. | Zhonghua xin xue guan bing za zhi 20070401 |
| Does addition of estradiol improve the efficacy of a rapamycin-eluting stent? Results of the ISAR-PEACE randomized trial. | Journal of the American College of Cardiology 20070327 |
| Epithelial-to-mesenchymal transition of human proximal tubular epithelial cells: effects of rapamycin, mycophenolate, cyclosporin, azathioprine, and methylprednisolone. | Transplantation 20070327 |
| Dual EGFR and mTOR targeting in squamous cell carcinoma models, and development of early markers of efficacy. | British journal of cancer 20070326 |
| Silencing mammalian target of rapamycin signaling by small interfering RNA enhances rapamycin-induced autophagy in malignant glioma cells. | Oncogene 20070322 |
| Rapamycin induces feedback activation of Akt signaling through an IGF-1R-dependent mechanism. | Oncogene 20070322 |
| For organ transplant recipients, cancer threatens long-term survival. | Journal of the National Cancer Institute 20070321 |
| Age-based clinical and angiographic outcomes after sirolimus-eluting stent implantation in patients with coronary artery disease. | Chinese medical journal 20070320 |
| Target of rapamycin (TOR) signaling controls epithelial morphogenesis in the vertebrate intestine. | Developmental biology 20070315 |
| Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II). | Human molecular genetics 20070315 |
| Results and predictors of angiographic restenosis and long-term adverse cardiac events after drug-eluting stent implantation for aorto-ostial coronary artery disease. | The American journal of cardiology 20070315 |
| Frequency of coronary arterial late angiographic stent thrombosis (LAST) in the first six months: outcomes with drug-eluting stents versus bare metal stents. | The American journal of cardiology 20070315 |
| In vivo and in vitro effect of sirolimus on insulin secretion. | Transplantation 20070315 |
| Rapamycin promotes emergence of IL-10-secreting donor lymphocyte infusion-derived T cells without compromising their graft-versus-leukemia reactivity. | Transplantation 20070315 |
| RAD001 (Everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer. | Cancer research 20070315 |
| [Pharmacodynamics of China-made rapamycin-polylactide-co-glycolide peripheral arterial eluting stent membrane: in vitro experiment]. | Zhonghua yi xue za zhi 20070313 |
| AKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitro. | The Journal of biological chemistry 20070309 |
| Stent thrombosis in randomized clinical trials of drug-eluting stents. | The New England journal of medicine 20070308 |
| Long-term outcomes with drug-eluting stents versus bare-metal stents in Sweden. | The New England journal of medicine 20070308 |
| Analysis of 14 trials comparing sirolimus-eluting stents with bare-metal stents. | The New England journal of medicine 20070308 |
| Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents. | The New England journal of medicine 20070308 |
| A pooled analysis of data comparing sirolimus-eluting stents with bare-metal stents. | The New England journal of medicine 20070308 |
| Unanswered questions--drug-eluting stents and the risk of late thrombosis. | The New England journal of medicine 20070308 |
| Late thrombosis of a drug-eluting stent overlapped in the in-stent restenotic lesion of a bare metal stent. | International journal of cardiology 20070302 |
| Regulation of translation factors eIF4GI and 4E-BP1 during recovery of protein synthesis from inhibition by p53. | Cell death and differentiation 20070301 |
| The YCR079w gene confers a rapamycin-resistant function and encodes the sixth type 2C protein phosphatase in Saccharomyces cerevisiae. | FEMS yeast research 20070301 |
| Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling. | Blood 20070301 |
| Rapamycin inhibits proliferation of estrogen-receptor-positive breast cancer cells. | The Journal of surgical research 20070301 |
| mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets. | Blood 20070301 |
| Metabolism of sirolimus in the presence or absence of cyclosporine by genotyped human liver microsomes and recombinant cytochromes P450 3A4 and 3A5. | Drug metabolism and disposition: the biological fate of chemicals 20070301 |
| In vivo inhibition of human hepatocellular carcinoma related angiogenesis by vinblastine and rapamycin. | Histology and histopathology 20070301 |
| Sirolimus causes relaxation of human vascular smooth muscle: a novel action of sirolimus mediated via ATP-sensitive potassium channels. | The Journal of pharmacology and experimental therapeutics 20070301 |
| Modeling of degradation and drug release from a biodegradable stent coating. | Journal of biomedical materials research. Part A 20070301 |
| Role of protein tyrosine phosphatases in the regulation of interferon-{gamma}-induced macrophage nitric oxide generation: implication of ERK pathway and AP-1 activation. | Journal of leukocyte biology 20070301 |
| Opposite effects of tor1 and tor2 on nitrogen starvation responses in fission yeast. | Genetics 20070301 |
| Negative regulation by p70 S6 kinase of FGF-2-stimulated VEGF release through stress-activated protein kinase/c-Jun N-terminal kinase in osteoblasts. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070301 |
| Utility of three-dimensional reconstruction of coronary angiography to guide percutaneous coronary intervention. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070301 |
| One-year results with extended-release tacrolimus/MMF, tacrolimus/MMF and cyclosporine/MMF in de novo kidney transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301 |
| Mycophenolate mofetil/sirolimus compared to other common immunosuppressive regimens in kidney transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301 |
| Calcineurin inhibitor-free protocols: risks and benefits. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20070301 |
| Mycotic pseudoaneurysm of the left circumflex coronary artery: a fatal complication following drug-eluting stent implantation. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070301 |
| Clobetasol ameliorates aphthous ulceration in renal transplant patients on sirolimus. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070301 |
| A clickable inhibitor reveals context-dependent autoactivation of p90 RSK. | Nature chemical biology 20070301 |
| FK506 binding protein 12/12.6 depletion increases endothelial nitric oxide synthase threonine 495 phosphorylation and blood pressure. | Hypertension (Dallas, Tex. : 1979) 20070301 |
| Proliferation signal inhibitors in cardiac transplantation. | Current opinion in cardiology 20070301 |
| New advances in antirejection therapy. | Current opinion in cardiology 20070301 |
| Regulatory T cells and T cell depletion: role of immunosuppressive drugs. | Journal of the American Society of Nephrology : JASN 20070301 |
| Pulmonary alveolar proteinosis: a rare pulmonary toxicity of sirolimus. | Transplant international : official journal of the European Society for Organ Transplantation 20070301 |
| Chemical rescue of cleft palate and midline defects in conditional GSK-3beta mice. | Nature 20070301 |
| Rapamycin-mediated G1 arrest involves regulation of the Cdk inhibitor Sic1 in Saccharomyces cerevisiae. | Molecular microbiology 20070301 |
| The treatment of multifocal choroiditis associated choroidal neovascularization with sirolimus (rapamycin). | Acta ophthalmologica Scandinavica 20070301 |
| Repeated drug-eluting stent implantation for drug-eluting stent restenosis: the same or a different stent. | American heart journal 20070301 |
| Angiographic analysis of pattern of late luminal loss in sirolimus- and paclitaxel-eluting stents. | The American journal of cardiology 20070301 |
| Comparison of effectiveness of bare metal stents versus drug-eluting stents in large (> or =3.5 mm) coronary arteries. | The American journal of cardiology 20070301 |
| An anti-aging drug today: from senescence-promoting genes to anti-aging pill. | Drug discovery today 20070301 |
| Mammalian target of rapamycin inhibitors as possible adjuvant therapy for microscopic residual disease in head and neck squamous cell cancer. | Cancer research 20070301 |
| Monitoring antitumor efficacy of rapamycin in Kaposi sarcoma. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20070301 |
| Islet transplantation. | The New England journal of medicine 20070301 |
| In-stent pseudo-restenosis due to an organized thrombus six months after implantation of a sirolimus-eluting stent. | The Journal of invasive cardiology 20070301 |
| Sirolimus-eluting stent implantation outside a previous stent. | The Journal of invasive cardiology 20070301 |
| Sirolimus-associated chronic pyogenic periungual infection. | Kidney international 20070301 |
| Reduced progression of endometrial hyperplasia with oral mTOR inhibition in the Pten heterozygote murine model. | American journal of obstetrics and gynecology 20070301 |
| Calcineurin inhibitor-free immunosuppression using everolimus (Certican) in maintenance heart transplant recipients: 6 months' follow-up. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070301 |
| Acute sirolimus pulmonary toxicity in an infant heart transplant recipient: case report and literature review. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20070301 |
| [Gene therapy for osteoarticular disorders]. | Medecine sciences : M/S 20070301 |
| The role of immunosuppressive drugs in aggravating renal ischemia and reperfusion injury. | Transplantation proceedings 20070301 |
| A role for HO-1 in renal function impairment in animals subjected to ischemic and reperfusion injury and treated with immunosuppressive drugs. | Transplantation proceedings 20070301 |
| Proteinuria in transplant patients associated with sirolimus. | Transplantation proceedings 20070301 |
| The effects of rapamycin in the progression of renal fibrosis. | Transplantation proceedings 20070301 |
| Five-year follow-up after late conversion from calcineurin inhibitors to sirolimus in patients with chronic renal allograft dysfunction. | Transplantation proceedings 20070301 |
| Is the malononitrilamide FK778 better for the prevention of acute or chronic rejection? | Transplantation proceedings 20070301 |
| Upstream signaling inhibition enhances rapamycin effect on growth of kidney cancer cells. | Urology 20070301 |
| Left main coronary artery stenosis: state-of-the-art. | Current problems in cardiology 20070301 |
| In-stent restenosis: 3 novel solutions show promise for heart patients. Stopping regrowth of plaque inside stents is a priority in reducing the need for repeat revascularizations. | DukeMedicine healthnews 20070301 |
| Initial and long-term outcomes of sirolimus-eluting stents for calcified lesions compared with bare-metal stents. | International heart journal 20070301 |
| Chemokines and chemokine receptors in renal transplantation--from bench to bedside. | Acta physiologica Hungarica 20070301 |
| [Treatment of intrastent restenosis by drug eluting stents: experience from one cardiology centre]. | Archives des maladies du coeur et des vaisseaux 20070301 |
| [Analysis of the mechanisms of thrombosis after implantation of drug-eluting stents]. | Zhonghua nei ke za zhi 20070301 |
| [Short and long-term therapeutic efficacy of drug-eluting stents (Firebird) for the treatment of coronary artery disease]. | Zhonghua xin xue guan bing za zhi 20070301 |
| Immunosuppression strategies in kidney transplantation. | Medicine and health, Rhode Island 20070301 |
| Sirolimus: defining nephrotoxicity in the renal transplant recipient. | Clinical journal of the American Society of Nephrology : CJASN 20070301 |
| High sirolimus levels may induce focal segmental glomerulosclerosis de novo. | Clinical journal of the American Society of Nephrology : CJASN 20070301 |
| Nanomedicines in renal transplant rejection--focus on sirolimus. | International journal of nanomedicine 20070301 |
| Effects of everolimus on cellular and humoral immune processes leading to chronic allograft nephropathy in a rat model with sensitized recipients. | Transplantation 20070227 |
| [Expression of connective tissue growth factor in renal interstitial fibrosis after ureteral obstruction and effects of rapamycin thereupon: experiment with rats]. | Zhonghua yi xue za zhi 20070227 |
| Early and late coronary stent thrombosis of sirolimus-eluting and paclitaxel-eluting stents in routine clinical practice: data from a large two-institutional cohort study. | Lancet (London, England) 20070224 |
| Trehalose, a novel mTOR-independent autophagy enhancer, accelerates the clearance of mutant huntingtin and alpha-synuclein. | The Journal of biological chemistry 20070223 |
| A novel mechanism for Bcr-Abl action: Bcr-Abl-mediated induction of the eIF4F translation initiation complex and mRNA translation. | Oncogene 20070222 |
| [Drug eluting stents: long term results in clinical practice. Comparison between rapamycin and paclitaxel eluting stents]. | Medicina clinica 20070217 |
| Rottlerin inhibits human T cell responses. | Biochemical pharmacology 20070215 |
| Incidence and clinical impact of coronary stent fracture after sirolimus-eluting stent implantation. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215 |
| Stent fracture associated with drug-eluting stents: clinical characteristics and implications. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215 |
| Detection of vascular endothelial growth factor (VEGF) and VEGF receptors Flt-1 and KDR in canine mastocytoma cells. | Veterinary immunology and immunopathology 20070215 |
| Treatment of recurrent pulmonary vein stenoses with endovascular stenting and adjuvant oral sirolimus. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070215 |
| A role for mammalian target of rapamycin in regulating T cell activation versus anergy. | Journal of immunology (Baltimore, Md. : 1950) 20070215 |
| Long-term graft outcomes after steroid withdrawal in African American kidney transplant recipients receiving sirolimus and tacrolimus. | Transplantation 20070215 |
| TSC1 sets the rate of ribosome export and protein synthesis through nucleophosmin translation. | Cancer research 20070215 |
| Akt/TSC/mTOR activation by the KSHV G protein-coupled receptor: emerging insights into the molecular oncogenesis and treatment of Kaposi's sarcoma. | Cell cycle (Georgetown, Tex.) 20070215 |
| Selective clearance of macrophages in atherosclerotic plaques by autophagy. | Journal of the American College of Cardiology 20070213 |
| Amino acid limitation induces expression of ATF5 mRNA at the post-transcriptional level. | Life sciences 20070206 |
| Randomized comparison of sirolimus and paclitaxel drug-eluting stents for long lesions in the left anterior descending artery: an intravascular ultrasound study. | Journal of the American College of Cardiology 20070206 |
| Effectiveness of drug-eluting stents in patients with bare-metal in-stent restenosis: meta-analysis of randomized trials. | Journal of the American College of Cardiology 20070206 |
| Development of coronary aneurysm after drug-eluting stent implantation. | Annals of internal medicine 20070206 |
| ER stress (PERK/eIF2alpha phosphorylation) mediates the polyglutamine-induced LC3 conversion, an essential step for autophagy formation. | Cell death and differentiation 20070201 |
| Case report: Corticosteroid-resistant nephrotic syndrome: treatment with rapamune. | Pediatric nephrology (Berlin, Germany) 20070201 |
| mTOR signaling in the hippocampus is necessary for memory formation. | Neurobiology of learning and memory 20070201 |
| Rapamycin inhibits the growth and muscle-sparing effects of clenbuterol. | Journal of applied physiology (Bethesda, Md. : 1985) 20070201 |
| Antiproliferative activity of RAD001 (everolimus) as a single agent and combined with other agents in mantle cell lymphoma. | Leukemia 20070201 |
| Antiproliferative agents alter vascular plasminogen activator inhibitor-1 expression: a potential prothrombotic mechanism of drug-eluting stents. | Arteriosclerosis, thrombosis, and vascular biology 20070201 |
| Aspects of mTOR biology and the use of mTOR inhibitors in non-Hodgkin's lymphoma. | Cancer treatment reviews 20070201 |
| Is late stent thrombosis in drug-eluting stents a real clinical issue? A single-center experience and review of the literature. | Clinical research in cardiology : official journal of the German Cardiac Society 20070201 |
| Short- and long-term effects of cytochalasin D, paclitaxel and rapamycin on wall thickening in experimental porcine vein grafts. | Cardiovascular research 20070201 |
| [Coronary stents and anaesthesia: it is time to have national data]. | Annales francaises d'anesthesie et de reanimation 20070201 |
| Relocation of minimal luminal diameter after bare metal and drug-eluting stent implantation: incidence and impact on angiographic late loss. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070201 |
| CYP3A5 genotype markedly influences the pharmacokinetics of tacrolimus and sirolimus in kidney transplant recipients. | Clinical pharmacology and therapeutics 20070201 |
| Effectiveness and safety of the sirolimus-eluting stents coated with bioabsorbable polymer coating in human coronary arteries. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070201 |
| Late restenosis following placement of a sirolimus eluting stent for in-stent restenosis. | Heart, lung & circulation 20070201 |
| Combining an mTOR antagonist and receptor tyrosine kinase inhibitors for the treatment of prostate cancer. | Cancer biology & therapy 20070201 |
| Severe psoriasis treated with a new macrolide: everolimus. | The British journal of dermatology 20070201 |
| Pharmacodynamics of T-cell function for monitoring immunosuppression. | Cell proliferation 20070201 |
| Switching from tacrolimus to sirolimus halts the appearance of new sebaceous neoplasms in Muir-Torre syndrome. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070201 |
| Emerging thrombotic effects of drug eluting stents. | Arteriosclerosis, thrombosis, and vascular biology 20070201 |
| Evaluation of the efficacy and safety of a slow conversion from calcineurin inhibitor- to sirolimus-based therapies in maintenance renal-transplant patients presenting with moderate renal insufficiency. | Transplant international : official journal of the European Society for Organ Transplantation 20070201 |
| Induction of chimerism in rhesus macaques through stem cell transplant and costimulation blockade-based immunosuppression. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070201 |
| Further delineation of the continuous human neoplastic enterochromaffin cell line, KRJ-I, and the inhibitory effects of lanreotide and rapamycin. | Journal of molecular endocrinology 20070201 |
| Impaired endothelial vasomotor function after sirolimus-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20070201 |
| Late angiographic stent thrombosis after sirolimus-eluting stent implantation. | Circulation journal : official journal of the Japanese Circulation Society 20070201 |
| Novel bioengineered small caliber vascular graft with excellent one-month patency. | The Annals of thoracic surgery 20070201 |
| Impact of pharmacometric reviews on new drug approval and labeling decisions--a survey of 31 new drug applications submitted between 2005 and 2006. | Clinical pharmacology and therapeutics 20070201 |
| Comparison of drug-eluting versus bare metal stents on later frequency of acute myocardial infarction and death. | The American journal of cardiology 20070201 |
| Outcome of overlapping heterogenous drug-eluting stents and of overlapping drug-eluting and bare metal stents. | The American journal of cardiology 20070201 |
| Sirolimus therapy of focal segmental glomerulosclerosis is associated with nephrotoxicity. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20070201 |
| The clinical outcome of percutaneous treatment of bifurcation lesions in multivessel coronary artery disease with the sirolimus-eluting stent: insights from the Arterial Revascularization Therapies Study part II (ARTS II). | European heart journal 20070201 |
| Bivalirudin versus heparin plus glycoprotein IIb/IIIa inhibitors in drug-eluting stent implantations in the absence of acute myocardial infarction: clinical and economic results. | The Journal of invasive cardiology 20070201 |
| Bivalirudin and DES: a PCI strategy that pays. | The Journal of invasive cardiology 20070201 |
| Fractured DES with a patent coronary artery: clinical implications. | The Journal of invasive cardiology 20070201 |
| Targeting mammalian target of rapamycin (mTOR) for health and diseases. | Drug discovery today 20070201 |
| Interplay of PI3K and cAMP/PKA signaling, and rapamycin-hypersensitivity in TGFbeta1 enhancement of FSH-stimulated steroidogenesis in rat ovarian granulosa cells. | The Journal of endocrinology 20070201 |
| American Society of Hematology--48th Annual Meeting and Exposition. Treatments for leukemia and lymphoma. 9-12 December 2006 Orlando, FL, USA. | IDrugs : the investigational drugs journal 20070201 |
| American Society of Hematology--48th Annual Meeting and Exposition. Updates on therapies. 9-12 December 2006 Orlando, FL, USA. | IDrugs : the investigational drugs journal 20070201 |
| Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions. Clinical and angiographic results of the ENDEAVOR II Trial. | Minerva cardioangiologica 20070201 |
| Keeping a high standard in quantitative analyses, meta-analyses, and systematic reviews. | European heart journal 20070201 |
| TCT Daily: Cypher more effective for long lesions. | Journal of interventional cardiology 20070201 |
| TCT Daily: ZOMAXX I--mixed results with zotarolimus-eluting stent. | Journal of interventional cardiology 20070201 |
| Adverse clinical events in patients treated with sirolimus-eluting stents: the impact of Type D personality. | European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 20070201 |
| Validation of immunological biomarkers for the pharmacodynamic monitoring of immunosuppressive drugs in humans. | Therapeutic drug monitoring 20070201 |
| Serum sickness-like reactions after placement of sirolimus-eluting stents. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20070201 |
| Requirements of phosphatidylinositol-3 kinase and mammalian target of rapamycin for estrogen-induced proliferation in uterine leiomyoma- and myometrium-derived cell lines. | American journal of obstetrics and gynecology 20070201 |
| Optimizing the development of targeted agents in pancreatic cancer: tumor fine-needle aspiration biopsy as a platform for novel prospective ex vivo drug sensitivity assays. | Molecular cancer therapeutics 20070201 |
| Combination of sublethal concentrations of epidermal growth factor receptor inhibitor and microtubule stabilizer induces apoptosis of glioblastoma cells. | Molecular cancer therapeutics 20070201 |
| Symptomatic failure after sirolimus-eluting stent implantation: a rare but challenging condition. | The Canadian journal of cardiology 20070201 |
| Orally administered rapamycin does not modify rat aortic vascular tone. | Journal of cardiovascular pharmacology 20070201 |
| [Progress on reasech of drug-coated stent]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20070201 |
| Thrombotic microangiopathy in a sirolimus-treated renal transplant patient receiving gemcitabine for lung cancer. | Clinical nephrology 20070201 |
| [Janus tacrolimus-eluting carbostent. Immediate and medium-term clinical results]. | Revista espanola de cardiologia 20070201 |
| The Development of rapamycin as an orphan drug. | Clinical advances in hematology & oncology : H&O 20070201 |
| Possible predictors of target lesion revascularization after drug-eluting stent implantation. | Journal of cardiology 20070201 |
| Proximal left anterior descending coronary artery revascularization with drug-eluting stents. | Arquivos brasileiros de cardiologia 20070201 |
| Impact of stable versus unstable coronary artery disease on 1-year outcome in elective patients undergoing multivessel revascularization with sirolimus-eluting stents: a subanalysis of the ARTS II trial. | Journal of the American College of Cardiology 20070130 |
| Unilateral upper extremity edema associated with sirolimus in a heart transplant patient. | Transplantation 20070127 |
| Ligand-regulated peptide aptamers that inhibit the 5'-AMP-activated protein kinase. | Journal of molecular biology 20070126 |
| A 'silent' polymorphism in the MDR1 gene changes substrate specificity. | Science (New York, N.Y.) 20070126 |
| Nutrient starvation promotes condensin loading to maintain rDNA stability. | The EMBO journal 20070124 |
| [Comparison of stenting with sirolimus eluting stent and spot stenting with small vessel stent in treatment of small vessels with long lesions]. | Zhonghua yi xue za zhi 20070123 |
| Phorbol 12-myristate 13-acetate and serum synergize to promote rapamycin-insensitive cell proliferation via protein kinase C-eta. | Oncogene 20070118 |
| Coronary artery stenting in a patient with angina pectoris caused by coronary artery dissection after blunt chest trauma. | International journal of cardiology 20070118 |
| Dilemma of drug-eluting stent implantation in a patient with systemic lupus erythematosus. | International journal of cardiology 20070118 |
| Long-term outcomes after management of restenosis or thrombosis of drug-eluting stents. | Journal of the American College of Cardiology 20070116 |
| Overexpression of the mTOR alpha4 phosphoprotein activates protein phosphatase 2A and increases Stat1alpha binding to PIAS1. | Molecular and cellular endocrinology 20070115 |
| Evaluating the activity of temsirolimus in neuroendocrine cancer. | British journal of cancer 20070115 |
| Sirolimus does not reduce receptor-mediated endocytosis of albumin in proximal tubule cells. | Transplantation 20070115 |
| [Drug-eluting or bare-metal stents in interventional cardiology. Theory and practice]. | Medizinische Klinik (Munich, Germany : 1983) 20070115 |
| The role of mammalian target of rapamycin inhibitors in the treatment of advanced renal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070115 |
| Clopidogrel use and long-term clinical outcomes after drug-eluting stent implantation. | JAMA 20070110 |
| Does clopidogrel each day keep stent thrombosis away? | JAMA 20070110 |
| Direct and indirect comparison meta-analysis demonstrates the superiority of sirolimus- versus paclitaxel-eluting stents across 5854 patients. | International journal of cardiology 20070102 |
| Coronary collateral function long after drug-eluting stent implantation. | Journal of the American College of Cardiology 20070102 |
| Attenuated coronary collateral function after drug-eluting stent implantation: a new downside of drug-eluting stents? | Journal of the American College of Cardiology 20070102 |
| Reactive oxygen species regulate insulin-induced VEGF and HIF-1alpha expression through the activation of p70S6K1 in human prostate cancer cells. | Carcinogenesis 20070101 |
| Rapamycin at subimmunosuppressive levels inhibits mesangial cell proliferation and extracellular matrix production. | American journal of physiology. Renal physiology 20070101 |
| A kinetically trapped intermediate of FK506 binding protein forms in vitro: chaperone machinery dominates protein folding in vivo. | Protein expression and purification 20070101 |
| Intramural delivery of Sirolimus prevents vascular remodeling following balloon injury. | Biochimica et biophysica acta 20070101 |
| Effects of rapamycin on cell proliferation and phosphorylation of mTOR and p70(S6K) in HepG2 and HepG2 cells overexpressing constitutively active Akt/PKB. | Biochimica et biophysica acta 20070101 |
| Acetaldehyde promotes rapamycin-dependent activation of p70(S6K) and glucose uptake despite inhibition of Akt and mTOR in dopaminergic SH-SY5Y human neuroblastoma cells. | Experimental neurology 20070101 |
| mTOR pathway as a target in tissue hypertrophy. | Annual review of pharmacology and toxicology 20070101 |
| In silico prediction of pregnane X receptor activators by machine learning approaches. | Molecular pharmacology 20070101 |
| Determination of everolimus in whole blood using the Abbott IMx sirolimus microparticle enzyme immunoassay. | Clinical biochemistry 20070101 |
| The pharmacodynamic effects of sirolimus and sirolimus-calcineurin inhibitor combinations on macrophage scavenger and nuclear hormone receptors. | Journal of pharmaceutical sciences 20070101 |
| Inhibition of restenosis development after mechanical injury: a new field of application for malononitrilamides? | Cardiology 20070101 |
| Constitutive activation of mTOR signaling pathway in post-transplant lymphoproliferative disorders. | Laboratory investigation; a journal of technical methods and pathology 20070101 |
| Mycophenolate acid inhibits endothelial NAD(P)H oxidase activity and superoxide formation by a Rac1-dependent mechanism. | Hypertension (Dallas, Tex. : 1979) 20070101 |
| A current problem in cardiology: very late thrombosis after implantation of sirolimus eluting stent. | Cardiology 20070101 |
| Persistent donor-specific alloreactivity may portend delayed liver rejection during drug minimization in children. | Frontiers in bioscience : a journal and virtual library 20070101 |
| The long-term value of sirolimus- and paclitaxel-eluting stents over bare metal stents in patients with diabetes mellitus. | European heart journal 20070101 |
| Epithelial-mesenchymal interactions in keloid pathogenesis modulate vascular endothelial growth factor expression and secretion. | The Journal of pathology 20070101 |
| Concurrent implantation of sirolimus- and paclitaxel-eluting stents in the same vessel. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101 |
| Intracoronary radiation therapy for multi-drug resistant in-stent restenosis: initial clinical experience. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101 |
| First-in-human implantation of a fully bioabsorbable drug-eluting stent: the BVS poly-L-lactic acid everolimus-eluting coronary stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101 |
| Incidence and predictors of recurrent restenosis following implantation of drug-eluting stents for in-stent restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101 |
| Two-year clinical outcome after coronary stenting of small vessels using 2.25-mm sirolimus- and paclitaxel-eluting stents: insight into the RESEARCH and T-SEARCH registries. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20070101 |
| Everolimus is a potent inducer of erythroid differentiation and gamma-globin gene expression in human erythroid cells. | Acta haematologica 20070101 |
| Total synthesis of rapamycin. | Angewandte Chemie (International ed. in English) 20070101 |
| Response of U87 glioma xenografts treated with concurrent rapamycin and fractionated radiotherapy: possible role for thrombosis. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070101 |
| Sirolimus-associated desquamative interstitial pneumonia. | Respiration; international review of thoracic diseases 20070101 |
| Drug-eluting stents: preventing restenosis. | Cardiology in review 20070101 |
| Shining a light on protein expression in living organisms. | Nature chemical biology 20070101 |
| Drug-eluting stents for the treatment of bifurcation lesions: a randomized comparison between paclitaxel and sirolimus stents. | American heart journal 20070101 |
| No robust conclusions to be drawn from clinical trials in the absence of an adequate control group. | Transplant international : official journal of the European Society for Organ Transplantation 20070101 |
| 12-month safety and efficacy of everolimus with reduced exposure cyclosporine in de novo renal transplant recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20070101 |
| Selective survival of naturally occurring human CD4+CD25+Foxp3+ regulatory T cells cultured with rapamycin. | Journal of immunology (Baltimore, Md. : 1950) 20070101 |
| Success rate of implantation and mid-term outcomes of the sirolimus-eluting stent. | Circulation journal : official journal of the Japanese Circulation Society 20070101 |
| XIENCE V everolimus-eluting coronary stent system: a novel second generation drug-eluting stent. | Expert review of medical devices 20070101 |
| Sirolimus promotes tolerance for donor and recipient antigens after MHC class II disparate bone marrow transplantation in rats. | Experimental hematology 20070101 |
| Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin. | The American journal of pathology 20070101 |
| Phosphatase targets in TOR signaling. | Methods in molecular biology (Clifton, N.J.) 20070101 |
| Effect of rapamycin on hepatocyte function and proliferation induced by growth factors. | Chemotherapy 20070101 |
| Everolimus-induced mTOR inhibition selectively depletes macrophages in atherosclerotic plaques by autophagy. | Autophagy 20070101 |
| Sirolimus improves early microcirculation, but impairs regeneration after pancreatic ischemia-reperfusion injury. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101 |
| Changes in renal function after clinical islet transplantation: four-year observational study. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20070101 |
| Very late restenosis of a sirolimus-eluting stent after left main coronary artery stenting. | The Canadian journal of cardiology 20070101 |
| Rapamycin as an inhibitor of osteogenic differentiation in bone marrow-derived mesenchymal stem cells. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20070101 |
| Chronic allograft nephropathy score before sirolimus rescue predicts allograft function in renal transplant patients. | Transplantation proceedings 20070101 |
| Four cases of sirolimus-associated interstitial pneumonitis: identification of risk factors. | Transplantation proceedings 20070101 |
| New immunosuppresor strategies in the treatment of murine lupus nephritis. | Lupus 20070101 |
| [Hemolytic uremic syndrome due to sirolimus in a heart transplant recipient. Case report]. | Revista espanola de cardiologia 20070101 |
| Drug-eluting stent implantation in ST-elevation acute myocardial infarction: 'real world' 30-day and mid-term results. | Cardiovascular revascularization medicine : including molecular interventions 20070101 |
| The ups and downs of sirolimus in kidney transplantation, and the importance of reporting negative findings. | The Netherlands journal of medicine 20070101 |
| Inferior results with basis immunosuppression with sirolimus in kidney transplantation. | The Netherlands journal of medicine 20070101 |
| Drug-eluting stent implantation in bifurcated lesions with balloon-crushing technique and 6 fr guiding catheter: immediate and mid-term results. | The Journal of invasive cardiology 20070101 |
| Treatment of a double-bifurcation lesion with sirolimus-eluting stents using the 'sleeve technique'. | The Journal of invasive cardiology 20070101 |
| Attenuation of PTEN increases p21 stability and cytosolic localization in kidney cancer cells: a potential mechanism of apoptosis resistance. | Molecular cancer 20070101 |
| How to treat recurrences of in-stent restenosis? | Internal medicine (Tokyo, Japan) 20070101 |
| Early steroid withdrawal therapy in renal transplant recipients: a steroid-free sirolimus and CellCept-based calcineurin inhibitor-minimization protocol. | Clinical transplantation 20070101 |
| The novel mTOR inhibitor RAD001 (everolimus) induces antiproliferative effects in human pancreatic neuroendocrine tumor cells. | Neuroendocrinology 20070101 |
| New therapeutics for soft-tissue sarcomas in adults. | Oncology (Williston Park, N.Y.) 20070101 |
| Rapamycin attenuates hypoxia-induced pulmonary vascular remodeling and right ventricular hypertrophy in mice. | Respiratory research 20070101 |
| Use of sirolimus in solid organ transplantation. | Drugs 20070101 |
| [Percutaneous coronary intervention for the elderly patients]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20070101 |
| Newly approved therapies for RCC and their effect on the standard of care. | Clinical advances in hematology & oncology : H&O 20070101 |
| A novel immunosuppressive agent, sirolimus, in the treatment of Kaposi's sarcoma in a renal transplant recipient. | Renal failure 20070101 |
| Do the benefits outweigh the risks with drug-eluting stents? | Scandinavian cardiovascular journal : SCJ 20070101 |
| Amino acids and insulin act additively to regulate components of the ubiquitin-proteasome pathway in C2C12 myotubes. | BMC molecular biology 20070101 |
| Angioedema in renal transplant recipients on sirolimus. | Dermatology (Basel, Switzerland) 20070101 |
| CCI-779 plus cisplatin is highly effective against human melanoma in a SCID mouse xenotranplantation model. | Pharmacology 20070101 |
| A potential screening tool for IPEX syndrome. | Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 20070101 |
| Angiographic and clinical outcome following sirolimus-eluting stent (Cypher) implantation. A single center experience. | International heart journal 20070101 |
| Molecularly targeted therapy for Kaposi's sarcoma in a kidney transplant patient: case report, 'what worked and what did not'. | BMC nephrology 20070101 |
| [Late localized aneurysmal dilations after sirolimus-eluting stents in 4 patients]. | Zhonghua xin xue guan bing za zhi 20070101 |
| Incidence of late stent thrombosis with bare-metal, sirolimus, and paclitaxel stents. | Reviews in cardiovascular medicine 20070101 |
| Rapamycin-induced inhibition of HTLV-I LTR activity is rescued by c-Myb. | Retrovirology 20070101 |
| [Stents in interventional cardiology]. | Medicina (Kaunas, Lithuania) 20070101 |
| Control of apoptosis in human multiple myeloma by insulin-like growth factor I (IGF-I). | Advances in cancer research 20070101 |
| Mechanisms of TSC-mediated control of synapse assembly and axon guidance. | PloS one 20070101 |
| Manipulating regulatory T cells. | Cytotherapy 20070101 |
| Rapamycin enriches for CD4(+) CD25(+) CD27(+) Foxp3(+) regulatory T cells in ex vivo-expanded CD25-enriched products from healthy donors and patients with multiple sclerosis. | Cytotherapy 20070101 |
| [Pro- and antitumor effects of the main immunosuppressive drugs used in the clinical practice of transplantation]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20070101 |
| Calcineurin inhibitor substitution with sirolimus vs. reduced-dose calcineurin inhibitor plus sirolimus is associated with improved renal dysfunction in heart transplant patients. | Clinical transplantation 20070101 |
| Factors influencing glomerular filtration rate in renal transplantation after cyclosporine withdrawal using sirolimus-based therapy: a multivariate analysis of results at five years. | Clinical transplantation 20070101 |
| Effects of sirolimus vs. calcineurin inhibitors on renal dysfunction after orthotopic liver transplantation. | Clinical transplantation 20070101 |
| Sirolimus inhibits key events of restenosis in vitro/ex vivo: evaluation of the clinical relevance of the data by SI/MPL- and SI/DES-ratios. | BMC cardiovascular disorders 20070101 |
| The next generation of drug-eluting stents: what's on the horizon? | American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101 |
| Rapamycin for treatment of refractory dysthyroid compressive optic neuropathy. | Ophthalmic plastic and reconstructive surgery 20070101 |
| Engineering aspects of stents design and their translation into clinical practice. | Annali dell'Istituto superiore di sanita 20070101 |
| Surgical wound-healing complications in heart transplant recipients treated with rapamycin. | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20070101 |
| Saccharomyces cerevisiae FKBP12 binds Arabidopsis thaliana TOR and its expression in plants leads to rapamycin susceptibility. | BMC plant biology 20070101 |
| Immunosuppression on the horizon. | Heart failure clinics 20070101 |
| When is retransplantation a viable option? | Heart failure clinics 20070101 |
| Advanced renal cell carcinoma: current and emerging management strategies. | Drugs 20070101 |
| Neointimal hyperplasia persists at six months after sirolimus-eluting stent implantation in diabetic porcine. | Cardiovascular diabetology 20070101 |
| The making of a queen: TOR pathway is a key player in diphenic caste development. | PloS one 20070101 |
| Effects of rapamycin on active Heymann nephritis. | American journal of nephrology 20070101 |
| Successful surgical treatment of an infected right coronary artery aneurysm-to-right ventricle fistula after sirolimus-eluting stent implantation. | Internal medicine (Tokyo, Japan) 20070101 |
| mTOR inhibitors (rapamycin and its derivatives) and nitrogen containing bisphosphonates: bi-functional compounds for the treatment of bone tumours. | Current medicinal chemistry 20070101 |
| The search for endothelium friendly stents. | Medical device technology 20070101 |
| Regulation of hepatic oval cell proliferation by adenoviral mediated hepatocyte growth factor gene transfer and signal transduction inhibitors. | Hepato-gastroenterology 20070101 |
| Everolimus retards cyst growth and preserves kidney function in a rodent model for polycystic kidney disease. | Kidney & blood pressure research 20070101 |
| Roles of mTOR and STAT3 in autophagy induced by telomere 3' overhang-specific DNA oligonucleotides. | Autophagy 20070101 |
| The role of targeted therapy in metastatic renal cell carcinoma. | TheScientificWorldJournal 20070101 |
| Beclin 1-independent pathway of damage-induced mitophagy and autophagic stress: implications for neurodegeneration and cell death. | Autophagy 20070101 |
| Cytotoxic effect of 5-aminoimidazole-4-carboxamide-1-beta-4-ribofuranoside (AICAR) on childhood acute lymphoblastic leukemia (ALL) cells: implication for targeted therapy. | Molecular cancer 20070101 |
| Risk factors for impaired wound healing in sirolimus-treated renal transplant recipients. | Clinical transplantation 20070101 |
| Sirolimus exposure during the early post-transplant period reduces the risk of CMV infection relative to tacrolimus in renal allograft recipients. | Clinical transplantation 20070101 |
| Clinical outcomes of renal transplant recipients treated with enteric-coated mycophenolic acid vs. mycophenolate mofetil as a switch agent using a primary steroid-free rapamune and microemulsion cyclosporine protocol. | Clinical transplantation 20070101 |
| Comparison of sirolimus and everolimus in their effects on blood lipid profiles and haematological parameters in heart transplant recipients. | Clinical transplantation 20070101 |
| [Effect of angiogenesis inhibitors on renal cell carcinoma]. | Magyar onkologia 20070101 |
| Immunosuppression for lung transplantation: evidence to date. | Drugs 20070101 |
| Rapamycin prevents early steps of the development of diabetic nephropathy in rats. | American journal of nephrology 20070101 |
| Targeting the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin module for acute myelogenous leukemia therapy: from bench to bedside. | Current medicinal chemistry 20070101 |
| Higher incidence of acute rejection in renal transplant recipients with low everolimus exposure. | Transplantation proceedings 20070101 |
| Sirolimus monotherapy in liver transplantation. | Transplantation proceedings 20070101 |
| Possible role of everolimus in improving renal function in long-term heart transplantation. | Transplantation proceedings 20070101 |
| Conversion to rapamycin immunosuppression for malignancy after kidney transplantation: case reports. | Transplantation proceedings 20070101 |
| Peritoneal leiomyosarcoma in a kidney transplant patient: a case report. | Transplantation proceedings 20070101 |
| Everolimus and mycophenolate mofetil sensitize human pancreatic cancer cells to gemcitabine in vitro: a novel adjunct to standard chemotherapy? | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20070101 |
| T-cell function monitoring in stable renal transplant patients treated with sirolimus monotherapy. | Molecular diagnosis & therapy 20070101 |
| Roles of cytokines in the pathogenesis and therapy of type 1 diabetes. | Cell biochemistry and biophysics 20070101 |
| Small molecule enhancers of rapamycin-induced TOR inhibition promote autophagy, reduce toxicity in Huntington's disease models and enhance killing of mycobacteria by macrophages. | Autophagy 20070101 |
| Immunoassay determination of rapamycin: reliability of the method with respect to liquid chromatography mass spectrometric quantification. | Clinical transplantation 20070101 |
| The use of sirolimus in ganciclovir-resistant cytomegalovirus infections in renal transplant recipients. | Clinical transplantation 20070101 |
| Promising new targeted agents in head and neck cancer. | International journal of radiation oncology, biology, physics 20070101 |
| New drugs: ambrisentan, temsirolimus, and eculizumab. | Journal of the American Pharmacists Association : JAPhA 20070101 |
| Clinical proof-of-concept trial to assess the therapeutic effect of sirolimus in patients with autosomal dominant polycystic kidney disease: SUISSE ADPKD study. | BMC nephrology 20070101 |
| Prevention of murine lupus disease in (NZBxNZW)F1 mice by sirolimus treatment. | Lupus 20070101 |
| Hematopoietic stem cell transplantation across major genetic barriers. | Immunologic research 20070101 |
| Molecule of the month. Temsirolimus. | Drug news & perspectives 20070101 |
| Effects of controlled-released sirolimus from polymer matrices on human coronary artery smooth muscle cells. | Journal of biomaterials science. Polymer edition 20070101 |
| [Angiogenesis targeting in renal carcinomas]. | Bulletin du cancer 20070101 |
| RAD inhibition of sarcoma growth: implications for laryngeal transplantation. | American journal of otolaryngology 20070101 |
| Tuberous sclerosis preclinical studies: timing of treatment, combination of a rapamycin analog (CCI-779) and interferon-gamma, and comparison of rapamycin to CCI-779. | BMC pharmacology 20070101 |
| Coupled down-regulation of mTOR and telomerase activity during fluorouracil-induced apoptosis of hepatocarcinoma cells. | BMC cancer 20070101 |
| [Clinical implications of coronary stents coated with drugs]. | Terapevticheskii arkhiv 20070101 |
| [Lymphangioleiomyomatosis and translational medicine]. | Medicina 20070101 |
| Development of an ultra-performance liquid chromatography technique coupled with mass spectrometry for the measurement of tacrolimus in micro-samples of whole blood, and its application on a pharmacokiinetic trial. | Arzneimittel-Forschung 20070101 |
| Clinical use of sirolimus-eluting stents. | Cardiovascular drug reviews 20070101 |
| Transcriptome of angiopoietin 1-activated human umbilical vein endothelial cells. | Endothelium : journal of endothelial cell research 20070101 |
| Conditional transgenesis using Dimerizable Cre (DiCre). | PloS one 20070101 |
| Unprotected left main coronary artery intervention for acute myocardial infarction and cardiogenic shock. | Texas Heart Institute journal 20070101 |
| Rapamycin enhances the anti-tumor effect of gemcitabine in pancreatic cancer cells. | Hepato-gastroenterology 20070101 |
| [Revascularization of the myocardium in patients with ischemic heart disease. Experience of the use of sirolimus eluting stents]. | Kardiologiia 20070101 |
| [Drug-eluting stent thrombosis and its pharmacological prevention]. | Kardiologiia 20070101 |
| [An experience of the use of stents with drug coating in patients with long and diffuse coronary artery lesions]. | Kardiologiia 20070101 |
| One-sided limb lymphedema in a liver transplant recipient receiving sirolimus. | Acta gastro-enterologica Belgica 20070101 |
| [Glioblastomas are resistant to apoptosis but less resistant to the autophagic process]. | Bulletin et memoires de l'Academie royale de medecine de Belgique 20070101 |
| [Sirolimus: mechanism of action, use in combined chemotherapy of cancer]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101 |
| Delayed stent fracture and aneurysm formation after sirolimus eluting stent. | Indian heart journal 20070101 |
| Pathology of drug-eluting stents: implications for coronary intervention. | Indian heart journal 20070101 |
| Taxus vs. Cypher: making sense of the 'evidence-based' data. | Indian heart journal 20070101 |
| Newer stents: looking at the horizon. | Indian heart journal 20070101 |
| Diabetic multivessel disease: stenting vs. coronary artery bypass grafting. | Indian heart journal 20070101 |
| Revascularizing diabetics: the CARDia trial. | Indian heart journal 20070101 |
| Pregnancy outcomes in solid organ transplant recipients with exposure to mycophenolate mofetil or sirolimus. | Transplantation 20061227 |
| Conversion to sirolimus in renal transplant recipients with skin cancer. | Transplantation 20061227 |
| Comparative analysis of calcineurin inhibition by complexes of immunosuppressive drugs with human FK506 binding proteins. | Biochemistry 20061226 |
| Combination treatment of low dose Anti-Thymocyte Globulin (ATG), Rituximab and high dose Sirolimus as induction agents in immune-conditioned recipients. | International immunopharmacology 20061220 |
| Affects of immunosuppression on circulating dendritic cells: an adjunct to therapeutic drug monitoring after heart transplantation. | International immunopharmacology 20061220 |
| Reccurence of Kaposi's sarcoma after increased exposure to sirolimus. | International immunopharmacology 20061220 |
| Randomized double-blind comparison of sirolimus-eluting stent versus bare-metal stent implantation in diseased saphenous vein grafts: six-month angiographic, intravascular ultrasound, and clinical follow-up of the RRISC Trial. | Journal of the American College of Cardiology 20061219 |
| Comparison of zotarolimus-eluting and sirolimus-eluting stents in patients with native coronary artery disease: a randomized controlled trial. | Journal of the American College of Cardiology 20061219 |
| Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents. | Journal of the American College of Cardiology 20061219 |
| Drug eluting stents. | BMJ (Clinical research ed.) 20061216 |
| Rapamycin promotes expansion of functional CD4+CD25+FOXP3+ regulatory T cells of both healthy subjects and type 1 diabetic patients. | Journal of immunology (Baltimore, Md. : 1950) 20061215 |
| Volumetric intravascular ultrasound assessment of neointimal hyperplasia and nonuniform stent strut distribution in sirolimus-eluting stent restenosis. | The American journal of cardiology 20061215 |
| Comparison of clinical outcomes of overlapping sirolimus- versus paclitaxel-eluting stents in patients undergoing percutaneous coronary intervention. | The American journal of cardiology 20061215 |
| Everolimus interferes with healing of experimental intestinal anastomoses. | Transplantation 20061215 |
| Targeting von Hippel-Lindau pathway in renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061215 |
| Translational control via the mammalian target of rapamycin pathway is critical for the formation and stability of long-term fear memory in amygdala neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20061213 |
| Targeted therapy for metastatic renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061210 |
| Saccharomyces cerevisiae Sit4 phosphatase is active irrespective of the nitrogen source provided, and Gln3 phosphorylation levels become nitrogen source-responsive in a sit4-deleted strain. | The Journal of biological chemistry 20061208 |
| Drug-eluting stents in primary PCI. | The New England journal of medicine 20061207 |
| Drug-eluting stents in primary PCI. | The New England journal of medicine 20061207 |
| Drug-eluting stents in primary PCI. | The New England journal of medicine 20061207 |
| Rapamycin decreases leukocyte migration in vivo and effectively reduces experimentally induced chronic colitis. | International journal of colorectal disease 20061201 |
| Sirolimus accelerates senescence of endothelial progenitor cells through telomerase inactivation. | Atherosclerosis 20061201 |
| Requirement of androgen-dependent activation of protein kinase Czeta for androgen-dependent cell proliferation in LNCaP Cells and its roles in transition to androgen-independent cells. | Molecular endocrinology (Baltimore, Md.) 20061201 |
| Everolimus drug interactions: application of a classification system for clinical decision making. | Biopharmaceutics & drug disposition 20061201 |
| Microwave expedited synthesis of 5-aminocamptothecin analogs: Inhibitors of hypoxia inducible factor HIF-1alpha. | Bioorganic & medicinal chemistry letters 20061201 |
| Rapid chemically induced changes of PtdIns(4,5)P2 gate KCNQ ion channels. | Science (New York, N.Y.) 20061201 |
| Autophagy for cancer therapy through inhibition of pro-apoptotic proteins and mammalian target of rapamycin signaling. | The Journal of biological chemistry 20061201 |
| Helicobacter pylori VacA toxin inhibits human immunodeficiency virus infection of primary human T cells. | Journal of virology 20061201 |
| Mortality in randomized controlled trials comparing drug-eluting vs. bare metal stents in coronary artery disease: a meta-analysis. | European heart journal 20061201 |
| Low-dose oral rapamycin treatment reduces fibrogenesis, improves liver function, and prolongs survival in rats with established liver cirrhosis. | Journal of hepatology 20061201 |
| Comparison of the Innofluor certican assay with HPLC-UV for the determination of everolimus concentrations in heart transplantation. | Clinical biochemistry 20061201 |
| Differential effects of immunosuppressive drugs on T-cell motility. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061201 |
| Blocking of Akt/NF-kappaB signaling by pentoxifylline inhibits platelet-derived growth factor-stimulated proliferation in Brown Norway rat airway smooth muscle cells. | Pediatric research 20061201 |
| Sirolimus as the main immunosuppressant in the early postoperative period following liver transplantation: a report of six cases and review of the literature. | Transplant international : official journal of the European Society for Organ Transplantation 20061201 |
| Sirolimus-eluting stents and calcified coronary lesions: clinical outcomes of patients treated with and without rotational atherectomy. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061201 |
| Sirolimus pharmacokinetic differences between children and adults. | Pediatric transplantation 20061201 |
| Sirolimus pharmacokinetics in pediatric renal transplant recipients receiving calcineurin inhibitor co-therapy. | Pediatric transplantation 20061201 |
| Premature discontinuation of antiplatelet therapy in patients with drug-eluting coronary stents. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20061201 |
| Cypher versus Taxus: the stent war. | Expert opinion on investigational drugs 20061201 |
| Cause of death with bare metal and sirolimus-eluting stents. | European heart journal 20061201 |
| Increased mortality after implantation of first generation drug-eluting stents: seeing the smoke, where is the fire? | European heart journal 20061201 |
| Cost-effectiveness of the unrestricted use of sirolimus-eluting stents vs. bare metal stents at 1 and 2-year follow-up: results from the RESEARCH Registry. | European heart journal 20061201 |
| Drug-eluting stents and stent thrombosis: a cause for concern? | Coronary artery disease 20061201 |
| Late stent thrombosis in drug-eluting stents: return of the 'VB syndrome'. | Nature clinical practice. Cardiovascular medicine 20061201 |
| Drug-eluting stent thrombosis: it's never too late. | Nature clinical practice. Cardiovascular medicine 20061201 |
| Revascularization of left anterior descending artery with drug-eluting stents: comparison with minimally invasive direct coronary artery bypass surgery. | The Annals of thoracic surgery 20061201 |
| Comparison with conventional therapies of repeated sirolimus-eluting stent implantation for the treatment of drug-eluting coronary stent restenosis. | The American journal of cardiology 20061201 |
| Safety and efficacy of the 2.25-mm sirolimus-eluting Bx Velocity stent in the treatment of patients with de novo native coronary artery lesions: the SIRIUS 2.25 trial. | The American journal of cardiology 20061201 |
| Comparison of the efficacy of direct coronary stenting with sirolimus-eluting stents versus stenting with predilation by intravascular ultrasound imaging (from the DIRECT trial). | The American journal of cardiology 20061201 |
| Conversion to sirolimus: a useful strategy for recalcitrant cutaneous viral warts in liver transplant recipient. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061201 |
| Rapamycin-mediated inhibition of mammalian target of rapamycin in skeletal muscle cells reduces glucose utilization and increases fatty acid oxidation. | Metabolism: clinical and experimental 20061201 |
| Brief review: coronary drug-eluting stents and anesthesia. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20061201 |
| Late thrombosis of drug-eluting stents: a meta-analysis of randomized clinical trials. | The American journal of medicine 20061201 |
| The evolving impact of microfabrication and nanotechnology on stent design. | Journal of vascular surgery 20061201 |
| Lipid oxidation and autophagy in yeast. | Free radical biology & medicine 20061201 |
| Targeting the AIB1 oncogene through mammalian target of rapamycin inhibition in the mammary gland. | Cancer research 20061201 |
| Drug-eluting and bare nitinol stents for the treatment of atherosclerotic lesions in the superficial femoral artery: long-term results from the SIROCCO trial. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20061201 |
| Comparison of sirolimus-eluting and bare metal stents in coronary bifurcation lesions: subgroup analysis of the Stenting Coronary Arteries in Non-Stress/Benestent Disease Trial (SCANDSTENT). | American heart journal 20061201 |
| Predictors of death or myocardial infarction during follow-up after coronary stenting with the sirolimus-eluting stent. Results from the prospective multicenter German Cypher Stent Registry. | American heart journal 20061201 |
| Angioscopic evaluation of neointima coverage: sirolimus drug-eluting stent versus bare metal stent. | American heart journal 20061201 |
| The role of therapeutic drug monitoring in individualizing immunosuppressive drug therapy: recent developments. | Therapeutic drug monitoring 20061201 |
| 12-hour area under the curve cyclosporine concentrations determined by a validated liquid chromatography-mass spectrometry procedure compared with fluorescence polarization immunoassay reveals sirolimus effect on cyclosporine pharmacokinetics. | Therapeutic drug monitoring 20061201 |
| [The role of caspase-3 in rapamycin-induced apoptosis of hepatocellular carcinoma BEL-7402 cells]. | Ai zheng = Aizheng = Chinese journal of cancer 20061201 |
| Farnesyltransferase inhibitors and rapamycin in the treatment of multiple myeloma. | Current pharmaceutical biotechnology 20061201 |
| Plumbagin induces G2-M arrest and autophagy by inhibiting the AKT/mammalian target of rapamycin pathway in breast cancer cells. | Molecular cancer therapeutics 20061201 |
| Changes in abdominal wounds following treatment with sirolimus and steroids in a rat model. | Transplantation proceedings 20061201 |
| Differential pharmacokinetic interaction of tacrolimus and cyclosporine on everolimus. | Transplantation proceedings 20061201 |
| Short-term results under three different immunosuppressive regimens at one center. | Transplantation proceedings 20061201 |
| Results of a calcineurin-inhibitor-free immunosuppressive protocol in renal transplant recipients of expanded criteria deceased donors. | Transplantation proceedings 20061201 |
| Sirolimus attenuates the rate of progression of early chronic allograft nephropathy. | Transplantation proceedings 20061201 |
| Proteinuria after conversion to sirolimus in renal transplant recipients. | Transplantation proceedings 20061201 |
| Post-rapamycin proteinuria: incidence, evolution, and therapeutic handling at a single center. | Transplantation proceedings 20061201 |
| Exposure-efficacy relationships of a fingolimod-everolimus regimen in kidney transplant patients at risk for delayed graft function. | Transplantation proceedings 20061201 |
| Risk factors for wound healing complications in sirolimus-treated renal transplant recipients. | Transplantation proceedings 20061201 |
| Characteristics of neoplasm occurrence and the therapeutic effect of sirolimus in South Chinese kidney transplant recipients. | Transplantation proceedings 20061201 |
| Predictors of decline in renal function after lung transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20061201 |
| Molecularly targeted therapy in renal cell carcinoma: where do we go from here? | Expert review of anticancer therapy 20061201 |
| Targeted therapies in metastatic renal cell carcinoma: the light at the end of the tunnel. | Expert review of anticancer therapy 20061201 |
| Effects of sirolimus on proteinuria and renal function in focal segmental glomerulonephritis. | International journal of clinical pharmacology and therapeutics 20061201 |
| Successful mobilization of peripheral blood stem cells by use of granulocyte-colony stimulating factor and their transcoronary transplantation in a patient after cardiogenic shock due to acute myocardial infarction. | The Journal of invasive cardiology 20061201 |
| Late stent thrombosis mimicking focal restenosis after sirolimus stent implantation: angiographic and intravascular ultrasound appraisal. | The Journal of invasive cardiology 20061201 |
| [Pulmonary toxicity associated with sirolimus therapy in liver transplantation]. | Gastroenterologia y hepatologia 20061201 |
| Apparent clearance of sirolimus in heart transplant recipients: impact of primary diagnosis and serum lipids. | Therapeutic drug monitoring 20061201 |
| Effects of tacrolimus or sirolimus on proliferation of vascular smooth muscle and endothelial cells. | Journal of cardiovascular pharmacology 20061201 |
| Temporal decline in sirolimus elimination immediately after pancreatic islet transplantation. | Drug metabolism and pharmacokinetics 20061201 |
| Renal function and histology in kidney transplant patients receiving tacrolimus and sirolimus or mycophenolate mofetil. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20061201 |
| [Initial and mid-term effects of > or = 30 mm long sirolimus-eluting stents in patients with diffuse long coronary lesions: comparison with bare metal stents]. | Journal of cardiology 20061201 |
| The growing role of mTOR in neuronal development and plasticity. | Molecular neurobiology 20061201 |
| [The clinical efficacy of sirolimus-eluting stents versus paclitaxel-eluting stents in complex and diffuse coronary lesions]. | Zhonghua nei ke za zhi 20061201 |
| Effect of rapamycin on the fate of P23H opsin associated with retinitis pigmentosa (an American Ophthalmological Society thesis). | Transactions of the American Ophthalmological Society 20061201 |
| The influence of copolymer chain microstructure on cyclosporine a (CyA) and Sirolimus prolonged and sustained release from PLA/TMC and PLA/PCL matrices. | Journal of controlled release : official journal of the Controlled Release Society 20061128 |
| Use of the organotypic culture method to investigate drug-loaded CSF shunt. | Journal of controlled release : official journal of the Controlled Release Society 20061128 |
| Ethoxyethyl methacrylate-based copolymers--a novel platform for drug-eluting stent coatings. | Journal of controlled release : official journal of the Controlled Release Society 20061128 |
| Generating rapamycin analogues by directed biosynthesis: starter acid substrate specificity of mono-substituted cyclohexane carboxylic acids. | Organic & biomolecular chemistry 20061121 |
| Newly identified c-KIT receptor tyrosine kinase ITD in childhood AML induces ligand-independent growth and is responsive to a synergistic effect of imatinib and rapamycin. | Blood 20061115 |
| Conversion from calcineurin inhibitors to sirolimus for chronic renal allograft dysfunction: a systematic review of the evidence. | Transplantation 20061115 |
| Combined transcriptional and translational targeting of EWS/FLI-1 in Ewing's sarcoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061115 |
| Combination mammalian target of rapamycin inhibitor rapamycin and HSP90 inhibitor 17-allylamino-17-demethoxygeldanamycin has synergistic activity in multiple myeloma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061115 |
| Early- and medium-term outcomes after paclitaxel-eluting stent implantation for sirolimus-eluting stent failure. | The American journal of cardiology 20061115 |
| Outcomes of 6906 patients undergoing percutaneous coronary intervention in the era of drug-eluting stents: report of the DEScover Registry. | Circulation 20061114 |
| Sirolimus-eluting stent versus paclitaxel-eluting stent for patients with long coronary artery disease. | Circulation 20061114 |
| Images in cardiovascular medicine. Damage to polymer of a sirolimus-eluting stent. | Circulation 20061114 |
| Recurrent restenosis in a patient with cardiac allograft vasculopathy: after angioplasty and sirolimus, paclitaxel saves the day. | International journal of cardiology 20061110 |
| Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways. | Oncogene 20061109 |
| Trading restenosis for thrombosis? New questions about drug-eluting stents. | The New England journal of medicine 20061109 |
| Connecting the dots using gene-expression profiles. | The New England journal of medicine 20061109 |
| A phase II clinical and pharmacodynamic study of temsirolimus in advanced neuroendocrine carcinomas. | British journal of cancer 20061106 |
| Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent? | The Journal of biological chemistry 20061103 |
| Targeting survivin via PI3K but not c-akt/PKB by anticancer drugs in immature neutrophils. | Oncogene 20061102 |
| Safety, tolerability, and efficacy of everolimus in de novo liver transplant recipients: 12- and 36-month results. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061101 |
| Regression of post-transplant Kaposi's sarcoma using sirolimus. | International journal of clinical practice 20061101 |
| Inclusion of MPA and in a rapid multi-drug LC-tandem mass spectrometric method for simultaneous determination of immunosuppressants. | Clinica chimica acta; international journal of clinical chemistry 20061101 |
| Controlled release of sirolimus from a multilayered PLGA stent matrix. | Biomaterials 20061101 |
| A downstream kinase of the mammalian target of rapamycin, p70S6K1, regulates human double minute 2 protein phosphorylation and stability. | Journal of cellular physiology 20061101 |
| Use of a stringent dimerizer-regulated gene expression system for controlled BMP2 delivery. | Molecular therapy : the journal of the American Society of Gene Therapy 20061101 |
| Cyclosporine withdrawal improves renal function in heart transplant patients on reduced-dose cyclosporine therapy. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061101 |
| Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients. | European journal of haematology 20061101 |
| Increase of proteinuria after conversion from calcineurin inhibitor to sirolimus-based treatment in kidney transplant patients with chronic allograft dysfunction. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061101 |
| The immunosuppressant rapamycin exacerbates neurotoxicity of Abeta peptide. | Journal of neuroscience research 20061101 |
| Nitrogen availability and TOR regulate the Snf1 protein kinase in Saccharomyces cerevisiae. | Eukaryotic cell 20061101 |
| Antiangiogenic and immunomodulatory effects of rapamycin on islet endothelium: relevance for islet transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20061101 |
| PTEN in the haematopoietic system and its therapeutic indications. | Trends in molecular medicine 20061101 |
| The role of heme oxygenase 1 in rapamycin-induced renal dysfunction after ischemia and reperfusion injury. | Kidney international 20061101 |
| Outcomes at 3 years of a prospective pilot study of Campath-1H and sirolimus immunosuppression for renal transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20061101 |
| Outcome in the real-world of coronary high-risk intervention with drug-eluting stents (ORCHID) -- a single-center study comparing Cypher sirolimus-eluting with Taxus paclitaxel-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101 |
| Randomized trial versus registry data--comparing apples and ORCHIDs. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101 |
| Stent thrombosis following the STAR technique in a complex RCA chronic total occlusion. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101 |
| Sirolimus for below the knee lesions: mid-term results of SiroBTK study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20061101 |
| Surfactant as a carrier: influence of immunosuppressive agents on surfactant activity. | Clinical physiology and functional imaging 20061101 |
| Chemotherapy disrupts activity of translational regulatory proteins in bone marrow stromal cells. | Experimental hematology 20061101 |
| Risk of noncardiac surgery after coronary drug-eluting stent implantation. | The American journal of cardiology 20061101 |
| Inflammatory response to drug-eluting stent placement. | The American journal of cardiology 20061101 |
| Everolimus and mTOR inhibitors in liver transplantation: opening the 'box'. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20061101 |
| Clinical and angiographic outcomes of sirolimus-eluting stents implantation in Japanese patients in daily practice. | Circulation journal : official journal of the Japanese Circulation Society 20061101 |
| Persistent malapposition after implantation of sirolimus-eluting stent into intramural coronary hematoma: optical coherence tomography observations. | Circulation journal : official journal of the Japanese Circulation Society 20061101 |
| Drug-eluting stents in total coronary occlusions: another piece of the puzzle solved? | American heart journal 20061101 |
| Sirolimus versus bare metal stent implantation in patients with total coronary occlusions: subgroup analysis of the Stenting Coronary Arteries in Non-Stress/Benestent Disease (SCANDSTENT) trial. | American heart journal 20061101 |
| Single-vessel versus bifurcation stenting for the treatment of distal left main coronary artery disease in the drug-eluting stenting era. Clinical and angiographic insights into the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) and Taxus-Stent Evaluated at Rotterdam Cardiology Hospital (T-SEARCH) registries. | American heart journal 20061101 |
| Comparison between drug-eluting stents and beta-radiation for the treatment of diffuse in-stent restenosis: clinical and angiographic outcomes. | American heart journal 20061101 |
| Progressive stent technologies: new approaches for the treatment of cardiovascular diseases. | Expert opinion on drug delivery 20061101 |
| Critics say drug-eluting stents overused. | JAMA 20061101 |
| Use of sirolimus for Epstein-Barr virus-positive smooth-muscle tumour. | The Lancet. Oncology 20061101 |
| Should the left main be covered entirely with drug-eluting stents in percutaneous intervention. | The Journal of invasive cardiology 20061101 |
| Incomplete stent apposition in a left main bifurcated lesion after kissing stent implantation. | The Journal of invasive cardiology 20061101 |
| Protein kinases as drug targets in cancer. | Current cancer drug targets 20061101 |
| Use of sirolimus to facilitate steroid withdrawal from a cyclosporine regimen. | Transplantation proceedings 20061101 |
| Initial single-center experience with sirolimus after lung transplantation. | Transplantation proceedings 20061101 |
| A monoselective sphingosine-1-phosphate receptor-1 agonist prevents allograft rejection in a stringent rat heart transplantation model. | Chemistry & biology 20061101 |
| Dissecting the mechanism of T-cell anergy with immunophilin ligands. | Current opinion in investigational drugs (London, England : 2000) 20061101 |
| Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic, colon, and breast tumors. | Molecular cancer therapeutics 20061101 |
| Drug-eluting stents--safety concerns. | Clinical cardiology 20061101 |
| [Promising efficacy of the sirolimus-eluting stent in patients with acute myocardial infarction]. | Journal of cardiology 20061101 |
| [Update on clinical activity of CCI779 (temsirolimus), mTOR inhibitor]. | Bulletin du cancer 20061101 |
| Case report: sirolimus associated interstitial lung disease. | South Dakota medicine : the journal of the South Dakota State Medical Association 20061101 |
| Late outcome of sirolimus-eluting stents: comparison of multidetector computed tomography with quantitative coronary angiography and intravascular ultrasound. | Arquivos brasileiros de cardiologia 20061101 |
| Very late stent thrombosis after implantation of drug eluting stent. | The Journal of the Association of Physicians of India 20061101 |
| BioMatrix Biolimus A9-eluting coronary stent: a next-generation drug-eluting stent for coronary artery disease. | Expert review of medical devices 20061101 |
| [Safety and efficacy comparison between rapamycin-eluting stent with biodegradable polymer or permanent polymer in patients with coronary artery disease]. | Zhonghua xin xue guan bing za zhi 20061101 |
| [Sirolimus inhibits the differentiation, proliferation and migration of endothelial progenitor cells in vitro]. | Zhonghua xin xue guan bing za zhi 20061101 |
| Beyond imatinib: second generation c-KIT inhibitors for the management of gastrointestinal stromal tumors. | Clinical colorectal cancer 20061101 |
| Randomized study on simple versus complex stenting of coronary artery bifurcation lesions: the Nordic bifurcation study. | Circulation 20061031 |
| [Drug-eluting coronary stents]. | Orvosi hetilap 20061029 |
| Images in cardiovascular medicine. Hypertrophic obstructive cardiomyopathy: septal ablation with overlapping sirolimus-eluting and covered stents after failed alcoholization and concomitant coronary artery disease. | Circulation 20061024 |
| Predicted mechanisms of resistance to mTOR inhibitors. | British journal of cancer 20061023 |
| Sirolimus-eluting stents vs brachytherapy for restenosis. | JAMA 20061018 |
| [Administration of sirolimus affects vein graft neointima hyperplasia]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20061018 |
| Unprotected left main disease: stent or surgery? | Journal of the American College of Cardiology 20061017 |
| mTOR and cancer therapy. | Oncogene 20061016 |
| Effect of plaque volume on subsequent vessel remodeling at edges of sirolimus-eluting stents. | The American journal of cardiology 20061015 |
| Sirolimus interferes with iron homeostasis in renal transplant recipients. | Transplantation 20061015 |
| Inhibition of mammalian target of rapamycin or apoptotic pathway induces autophagy and radiosensitizes PTEN null prostate cancer cells. | Cancer research 20061015 |
| Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling. | Oncogene 20061012 |
| Switch from cyclosporine to sirolimus as a treatment of acute renal failure complicating cardiogenic shock in a heart transplant recipient. | International journal of cardiology 20061010 |
| Rapamycin biosynthesis: Elucidation of gene product function. | Organic & biomolecular chemistry 20061007 |
| Activity- and mTOR-dependent suppression of Kv1.1 channel mRNA translation in dendrites. | Science (New York, N.Y.) 20061006 |
| Vessel size and outcome after coronary drug-eluting stent placement: results from a large cohort of patients treated with sirolimus- or paclitaxel-eluting stents. | Journal of the American College of Cardiology 20061003 |
| All drug-eluting stents are equal, but some drug-eluting stents are more equal than others. | Journal of the American College of Cardiology 20061003 |
| Clinical outcomes for sirolimus-eluting stents and polymer-coated paclitaxel-eluting stents in daily practice: results from a large multicenter registry. | Journal of the American College of Cardiology 20061003 |
| Citrus auraptene targets translation of MMP-7 (matrilysin) via ERK1/2-dependent and mTOR-independent mechanism. | FEBS letters 20061002 |
| Recurrence of proteinuria 10 years post-transplant in NPHS2-associated focal segmental glomerulosclerosis after conversion from cyclosporin A to sirolimus. | Pediatric nephrology (Berlin, Germany) 20061001 |
| Mammalian target of rapamycin regulates the growth of mammary epithelial cells through the inhibitor of deoxyribonucleic acid binding Id1 and their functional differentiation through Id2. | Molecular endocrinology (Baltimore, Md.) 20061001 |
| Combination of a rapamycin analog (CCI-779) and interferon-gamma is more effective than single agents in treating a mouse model of tuberous sclerosis complex. | Genes, chromosomes & cancer 20061001 |
| Everolimus inhibits glomerular endothelial cell proliferation and VEGF, but not long-term recovery in experimental thrombotic microangiopathy. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20061001 |
| Registry data evaluating the effectiveness of drug-eluting stents for the treatment of symptomatic in-stent restenosis. | Heart, lung & circulation 20061001 |
| The impact of the mTOR inhibitor sirolimus on the proliferation and function of pancreatic islets and ductal cells. | Diabetologia 20061001 |
| Proteinuria following conversion from azathioprine to sirolimus in renal transplant recipients. | Kidney international 20061001 |
| The proangiogenic phenotype of human tumor-derived endothelial cells depends on thrombospondin-1 downregulation via phosphatidylinositol 3-kinase/Akt pathway. | Journal of molecular medicine (Berlin, Germany) 20061001 |
| Patterns of restenosis after drug-eluting stent implantation: Insights from a contemporary and comparative analysis of sirolimus- and paclitaxel-eluting stents. | European heart journal 20061001 |
| Calcineurin-inhibitor induced pain syndrome after organ transplantation. | Kidney international 20061001 |
| Safety, feasibility, and short-term follow-up of drug-eluting stent placement in the intracranial and extracranial circulation. | Stroke 20061001 |
| Effect of rapamycin on renal ischemia-reperfusion injury in mice. | Transplant international : official journal of the European Society for Organ Transplantation 20061001 |
| Sirolimus monotherapy versus sirolimus in combination with steroids and/or MMF for immunosuppression after liver transplantation. | Digestive diseases and sciences 20061001 |
| Investigating mammalian target of rapamycin inhibitors for their anticancer properties. | Expert opinion on investigational drugs 20061001 |
| A Bayesian approach for population pharmacokinetic modelling of sirolimus. | British journal of clinical pharmacology 20061001 |
| A comparison of the effect of ciclosporin and sirolimus on the pharmokinetics of mycophenolate in renal transplant patients. | British journal of clinical pharmacology 20061001 |
| Three-year clinical follow-up of the unrestricted use of sirolimus-eluting stents as part of the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry. | The American journal of cardiology 20061001 |
| Clinical and angiographic outcomes after placement of multiple overlapping drug-eluting stents in diffuse coronary lesions. | The American journal of cardiology 20061001 |
| Monomorphic Epstein-Barr virus (EBV)-associated large B-cell posttransplant lymphoproliferative disorder presenting as a tongue ulcer in a pancreatic transplant patient. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20061001 |
| Mycophenolate mofetil versus sirolimus as an adjunct to calcineurin inhibition after renal transplantation. | Nature clinical practice. Nephrology 20061001 |
| Gene expression-based chemical genomics identifies rapamycin as a modulator of MCL1 and glucocorticoid resistance. | Cancer cell 20061001 |
| Sirolimus monotherapy for Kaposi's sarcoma in an HIV-negative patient. | The Lancet. Oncology 20061001 |
| Autophagy in cancer: good, bad, or both? | Cancer research 20061001 |
| Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer. | Cancer research 20061001 |
| Clinical evidence on polymer-based sirolimus and paclitaxel eluting stents. | Minerva cardioangiologica 20061001 |
| How to treat diabetic patients with multivesseal disease in the DES era. | Minerva cardioangiologica 20061001 |
| Overview of pharmacology and clinical trials program with the zotarolimus-eluting endeavor stent. | Journal of interventional cardiology 20061001 |
| A phase I and pharmacokinetic study of temsirolimus (CCI-779) administered intravenously daily for 5 days every 2 weeks to patients with advanced cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061001 |
| Role of the Fusarium fujikuroi TOR kinase in nitrogen regulation and secondary metabolism. | Eukaryotic cell 20061001 |
| A temporal switch in the insulin-signalling pathway that regulates hepatic IGF-binding protein-1 gene expression. | Journal of molecular endocrinology 20061001 |
| Sirolimus--challenging current perspectives. | Therapeutic drug monitoring 20061001 |
| Apparent clearance of sirolimus in heart transplant recipients: impact of primary diagnosis and serum lipids. | Therapeutic drug monitoring 20061001 |
| Safety and pharmacokinetics of sirolimus-eluting stents in the canine cerebral vasculature: 180 day assessment. | Neurosurgery 20061001 |
| Signaling interactions of rapamycin combined with erlotinib in cervical carcinoma xenografts. | Molecular cancer therapeutics 20061001 |
| The antitumor effects of sunitinib (formerly SU11248) against a variety of human hematologic malignancies: enhancement of growth inhibition via inhibition of mammalian target of rapamycin signaling. | Molecular cancer therapeutics 20061001 |
| Balloon alignment T-stenting for bifurcation coronary artery disease using the sirolimus-eluting stent. | The Journal of invasive cardiology 20061001 |
| Sirolimus-eluting stenting of the external carotid artery for the treatment of ocular ischemia. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20061001 |
| Iliac anastomotic stenting with a sirolimus-eluting biodegradable poly-L-lactide stent: a preliminary study after 6 weeks. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20061001 |
| Molecular biology of renal cell carcinoma. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20061001 |
| Mammalian target of rapamycin inhibitors in combination with letrozole in breast cancer. | Clinical breast cancer 20061001 |
| Calcineurin inhibitors affect circulating regulatory T cells in stable renal transplant recipients. | Transplantation proceedings 20061001 |
| Conversion to everolimus in kidney transplant recipients: a safe and simple procedure. | Transplantation proceedings 20061001 |
| Pulmonary toxicity associated with sirolimus treatment in kidney transplantation. | Transplantation proceedings 20061001 |
| Conversion to sirolimus in renal transplant patients with tumors. | Transplantation proceedings 20061001 |
| Conversion from calcineurin inhibitors to everolimus in kidney transplant recipients with malignant neoplasia. | Transplantation proceedings 20061001 |
| Sirolimus experience in heart transplantation. | Transplantation proceedings 20061001 |
| Sirolimus attenuates chronic allograft nephropathy in an experimental rat kidney transplantation model. | Transplantation proceedings 20061001 |
| [Efficacy of sirolimus-eluting stent implantation in diabetic patients with very small vessels (< or = 2.25 mm). Insights from the DIABETES trial]. | Revista espanola de cardiologia 20061001 |
| Living donor islet transplantation, the alternative approach to overcome the obstacles limiting transplant. | Annals of the New York Academy of Sciences 20061001 |
| Direct versus predilatation drug-eluting stenting: a randomized clinical trial. | The Journal of invasive cardiology 20061001 |
| Generation of HSP60-specific regulatory T cell and effect on atherosclerosis. | Cellular immunology 20061001 |
| The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease. | Science (New York, N.Y.) 20060929 |
| Rapamycin and dendritic cells: keep on movin'. | Transplantation 20060927 |
| Development of de novo cancer in p53 knock-out mice is dependent on the type of long-term immunosuppression used. | Transplantation 20060927 |
| Differential effects of immunosuppressive drugs on chemokine receptor CCR7 in human monocyte-derived dendritic cells: selective upregulation by rapamycin. | Transplantation 20060927 |
| mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s. | Current biology : CB 20060919 |
| Human cytomegalovirus infection alters the substrate specificities and rapamycin sensitivities of raptor- and rictor-containing complexes. | Proceedings of the National Academy of Sciences of the United States of America 20060919 |
| Characterization of plaque prolapse after drug-eluting stent implantation in diabetic patients: a three-dimensional volumetric intravascular ultrasound outcome study. | Journal of the American College of Cardiology 20060919 |
| Rapamycin improves lymphoproliferative disease in murine autoimmune lymphoproliferative syndrome (ALPS). | Blood 20060915 |
| Comparison of outcomes between bare metal stents and drug-eluting stents for percutaneous revascularization of internal mammary grafts. | The American journal of cardiology 20060915 |
| Acute renal failure following kidney transplantation associated with myoglobinuria in patients treated with rapamycin. | Transplantation 20060915 |
| Sirolimus-eluting versus uncoated stents in acute myocardial infarction. | The New England journal of medicine 20060914 |
| Drug-eluting stents in acute myocardial infarction. | The New England journal of medicine 20060914 |
| Release of anti-restenosis drugs from poly(ethylene oxide)-poly(DL-lactic-co-glycolic acid) nanoparticles. | Journal of controlled release : official journal of the Controlled Release Society 20060912 |
| Inhibition of mammalian target of rapamycin modulates expression of adhesion molecules in endothelial cells. | Toxicology letters 20060910 |
| Targeting protein stability with a small molecule. | Cell 20060908 |
| Mind the GAP: Wnt steps onto the mTORC1 train. | Cell 20060908 |
| TSC2 integrates Wnt and energy signals via a coordinated phosphorylation by AMPK and GSK3 to regulate cell growth. | Cell 20060908 |
| Three new drugs available to fight kidney cancer. | Journal of the National Cancer Institute 20060906 |
| Cyclosporin A, tacrolimus and sirolimus are potent inhibitors of the human breast cancer resistance protein (ABCG2) and reverse resistance to mitoxantrone and topotecan. | Cancer chemotherapy and pharmacology 20060901 |
| Leucine in food mediates some of the postprandial rise in plasma leptin concentrations. | American journal of physiology. Endocrinology and metabolism 20060901 |
| Fibroblasts isolated from human pterygia exhibit altered lipid metabolism characteristics. | Experimental eye research 20060901 |
| Co-administration of sirolimus alters tacrolimus pharmacokinetics in a dose-dependent manner in adult renal transplant recipients. | Pharmacological research 20060901 |
| Sirolimus conversion for patients with posttransplant Kaposi's sarcoma. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901 |
| mTOR inhibition induces endothelial progenitor cell death. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901 |
| Rheb inhibits C-raf activity and B-raf/C-raf heterodimerization. | The Journal of biological chemistry 20060901 |
| Prolongation of allograft survival by administration of anti-CD45RB monoclonal antibody is due to alteration of CD45RBhi: CD45RBlo T-cell proportions. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901 |
| Role of P-glycoprotein in cyclosporine cytotoxicity in the cyclosporine-sirolimus interaction. | Kidney international 20060901 |
| ['HAART-attack' in young female HIV-patient]. | Der Internist 20060901 |
| Effect of sirolimus in the prevention of adhesions around intraabdominal prosthetic graft. | World journal of surgery 20060901 |
| Mammalian target of rapamycin inhibition induces cell cycle arrest in diffuse large B cell lymphoma (DLBCL) cells and sensitises DLBCL cells to rituximab. | British journal of haematology 20060901 |
| The place of sirolimus in kidney transplantation: can we reduce calcineurin inhibitor renal toxicity? | Kidney international 20060901 |
| Akt and Mammalian target of rapamycin regulate separate systems of proteolysis in renal tubular cells. | Journal of the American Society of Nephrology : JASN 20060901 |
| Improved survival with drug-eluting stent implantation in comparison with bare metal stent in patients with severe left ventricular dysfunction. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901 |
| Very late [corrected] thrombosis of a sirolimus-eluting stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901 |
| The role of BMS in the drug eluting stent era: is still there any place for them? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060901 |
| Angioscopic differences in neointimal coverage and in persistence of thrombus between sirolimus-eluting stents and bare metal stents after a 6-month implantation. | European heart journal 20060901 |
| Rapamycin induces regression of endometriotic lesions by inhibiting neovascularization and cell proliferation. | British journal of pharmacology 20060901 |
| Delayed neointimal healing after drug-eluting stent implantation: seeing is believing. | European heart journal 20060901 |
| New treatment approaches in metastatic renal cell carcinoma. | Current opinion in urology 20060901 |
| Treatment strategies in pediatric solid organ transplant recipients with calcineurin inhibitor-induced nephrotoxicity. | Pediatric transplantation 20060901 |
| Amiodarone-sirolimus/tacrolimus interaction in a pediatric heart transplant patient. | Pediatric transplantation 20060901 |
| Effect of SU11248 on gastrointestinal stromal tumor-T1 cells: enhancement of growth inhibition via inhibition of 3-kinase/Akt/mammalian target of rapamycin signaling. | Cancer science 20060901 |
| Ex vivo rapamycin generates Th1/Tc1 or Th2/Tc2 Effector T cells with enhanced in vivo function and differential sensitivity to post-transplant rapamycin therapy. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060901 |
| Relation of C-reactive protein level and long-term risk of death or myocardial infarction following percutaneous coronary intervention with a sirolimus-eluting stent. | The American journal of cardiology 20060901 |
| Investigating the caffeine effects in the yeast Saccharomyces cerevisiae brings new insights into the connection between TOR, PKC and Ras/cAMP signalling pathways. | Molecular microbiology 20060901 |
| Mycophenolate mofetil and sirolimus combination in renal transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060901 |
| Antitumoral activity of rapamycin in renal angiomyolipoma associated with tuberous sclerosis complex. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20060901 |
| Sirolimus is associated with reduced islet engraftment and impaired beta-cell function. | Diabetes 20060901 |
| Constitutive phosphorylation of the S6 ribosomal protein via mTOR and ERK signaling in the peripheral blasts of acute leukemia patients. | Experimental hematology 20060901 |
| Rapamycin reduces disease activity and normalizes T cell activation-induced calcium fluxing in patients with systemic lupus erythematosus. | Arthritis and rheumatism 20060901 |
| [Effect of rapamycin and dexamethasone on differentiation and maturation of murine bone marrow-derived dendritic cells]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20060901 |
| Phase I/II study of the mammalian target of rapamycin inhibitor everolimus (RAD001) in patients with relapsed or refractory hematologic malignancies. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060901 |
| Natural Products in Drug Discovery & Development II--2nd annual Taylor & Francis conference. 21-22 June 2006, London, UK. | IDrugs : the investigational drugs journal 20060901 |
| Drug evaluation: AP-23573--an mTOR inhibitor for the treatment of cancer. | IDrugs : the investigational drugs journal 20060901 |
| Combination therapy for treating breast cancer using antiestrogen, ERA-923, and the mammalian target of rapamycin inhibitor, temsirolimus. | Endocrine-related cancer 20060901 |
| Sirolimus-associated interstitial pneumonitis in 3 heart transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060901 |
| [Nephrotoxicity of sirolimus: experimental and clinical data]. | Nephrologie & therapeutique 20060901 |
| Therapeutic targets: MTOR and related pathways. | Cancer biology & therapy 20060901 |
| Influence of everolimus on cyclosporine Neoral pharmacokinetics in Chinese de novo cardiac transplant recipients. | Transplantation proceedings 20060901 |
| Therapeutic drug monitoring of cyclosporine Neoral in de novo Chinese cardiac transplant recipients treated with an everolimus-cyclosporine immunosuppressive regimen. | Transplantation proceedings 20060901 |
| Comparison of rapamycin versus FK506 on expression of cytoprotective genes in the rat kidney allografts undergoing chronic allograft nephropathy. | Transplantation proceedings 20060901 |
| Evaluation of an immunoassay (Abbott-IMX Analyzer) allowing routine determination of sirolimus: comparison with LC-MS method. | Transplantation proceedings 20060901 |
| Phosphatidylinositol 3-kinase/Akt plays a part in tumor necrosis factor-alpha-induced interleukin-6 synthesis in osteoblasts. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20060901 |
| Cyclin D3 is down-regulated by rapamycin in HER-2-overexpressing breast cancer cells. | Molecular cancer therapeutics 20060901 |
| Aging and immortality: quasi-programmed senescence and its pharmacologic inhibition. | Cell cycle (Georgetown, Tex.) 20060901 |
| Use of APO2L/TRAIL with mTOR inhibitors in the treatment of glioblastoma multiforme. | Expert review of anticancer therapy 20060901 |
| Stenting of unprotected left main coronary artery in patients with low preoperative risk of coronary artery bypass grafting. | Kardiologia polska 20060901 |
| Effectiveness of a sirolimus-eluting stent (Cypher) for diffuse in-stent restenosis inside a bare metal stent. | International heart journal 20060901 |
| Late angiographic stent thrombosis in a drug-eluting stent that occurred 20 months after premature discontinuation of clopidogrel administration. | International heart journal 20060901 |
| Revascularization of malignant coronary instent restenosis resulting from Takayasu's arteritis using sirolimus-eluting stents. | International heart journal 20060901 |
| The Akt/mTOR and mitogen-activated protein kinase pathways in lung cancer therapy. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060901 |
| Steroid sparing in kidney transplantation: changing paradigms, improving outcomes, and remaining questions. | Clinical journal of the American Society of Nephrology : CJASN 20060901 |
| Sirolimus therapy following early cyclosporine withdrawal in transplant patients: mechanisms of action and clinical results. | International journal of nanomedicine 20060901 |
| Current status of clinical trials for glioblastoma. | Reviews on recent clinical trials 20060901 |
| Nutrient regulates Tor1 nuclear localization and association with rDNA promoter. | Nature 20060831 |
| Primary Stenting of Totally Occluded Native Coronary Arteries II (PRISON II): a randomized comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of total coronary occlusions. | Circulation 20060829 |
| The FRB domain of mTOR: NMR solution structure and inhibitor design. | Biochemistry 20060829 |
| Tacrolimus and sirolimus cause insulin resistance in normal sprague dawley rats. | Transplantation 20060827 |
| Calcineurin inhibitors, but not rapamycin, reduce percentages of CD4+CD25+FOXP3+ regulatory T cells in renal transplant recipients. | Transplantation 20060827 |
| TOR regulates late steps of ribosome maturation in the nucleoplasm via Nog1 in response to nutrients. | The EMBO journal 20060823 |
| Randomized, double-blind, multicenter study of the Endeavor zotarolimus-eluting phosphorylcholine-encapsulated stent for treatment of native coronary artery lesions: clinical and angiographic results of the ENDEAVOR II trial. | Circulation 20060822 |
| Letter by Tsai et al regarding article, 'correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and Paclitaxel-eluting stents'. | Circulation 20060822 |
| PML inhibits HIF-1alpha translation and neoangiogenesis through repression of mTOR. | Nature 20060817 |
| A developmental transition in growth control during zebrafish caudal fin development. | Developmental biology 20060815 |
| Outcome after acute incomplete sirolimus-eluting stent apposition as assessed by serial intravascular ultrasound. | The American journal of cardiology 20060815 |
| Angiographic results of the first human experience with the Biolimus A9 drug-eluting stent for de novo coronary lesions. | The American journal of cardiology 20060815 |
| Effect of everolimus-eluting stents in different vessel sizes (from the pooled FUTURE I and II trials). | The American journal of cardiology 20060815 |
| Differences in proteinuria and graft function in de novo sirolimus-based vs. calcineurin inhibitor-based immunosuppression in live donor kidney transplantation. | Transplantation 20060815 |
| Delayed gastric ulcer healing associated with sirolimus. | Transplantation 20060815 |
| Mammalian target of rapamycin inhibition promotes response to epidermal growth factor receptor kinase inhibitors in PTEN-deficient and PTEN-intact glioblastoma cells. | Cancer research 20060815 |
| Patency of the left coronary artery by 64-slice multislice computed tomography following implantation of sirolimus-eluting stent. | International journal of cardiology 20060810 |
| Rapamycin activates Tap42-associated phosphatases by abrogating their association with Tor complex 1. | The EMBO journal 20060809 |
| Spatial memory formation and memory-enhancing effect of glucose involves activation of the tuberous sclerosis complex-Mammalian target of rapamycin pathway. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060802 |
| Effects of a combined treatment with mTOR inhibitor RAD001 and tamoxifen in vitro on growth and apoptosis of human cancer cells. | Gynecologic oncology 20060801 |
| Neointimal proliferation around malapposed struts of a sirolimus-eluting stent: optical coherence tomography findings. | European heart journal 20060801 |
| Switching immunosuppression medications after renal transplantation--a common practice. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801 |
| Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells. | Blood 20060801 |
| Hypoxia-inducible factor-1-dependent and -independent regulation of insulin-like growth factor-1-stimulated vascular endothelial growth factor secretion. | The Journal of pharmacology and experimental therapeutics 20060801 |
| Nephrotoxicity of ciclosporin A: short-term gain, long-term pain? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060801 |
| Rapamycin confers preconditioning-like protection against ischemia-reperfusion injury in isolated mouse heart and cardiomyocytes. | Journal of molecular and cellular cardiology 20060801 |
| Rapamycin (sirolimus): a two-edged sword? | Journal of molecular and cellular cardiology 20060801 |
| Characterisation of the lung toxicity of the cell cycle inhibitor temsirolimus. | European journal of cancer (Oxford, England : 1990) 20060801 |
| Vascularization and engraftment of a human skin substitute using circulating progenitor cell-derived endothelial cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060801 |
| Chronic inhibition of mammalian target of rapamycin signaling downregulates insulin receptor substrates 1 and 2 and AKT activation: A crossroad between cancer and diabetes? | Journal of the American Society of Nephrology : JASN 20060801 |
| Long-term effects of novel biolimus eluting DEVAX AXXESS plus nitinol self-expanding stent in a porcine coronary model. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060801 |
| Oral sirolimus after bare metal stent implantation. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060801 |
| Evaluation of the haemodynamic characteristics of drug-eluting stents at implantation and at follow-up. | European heart journal 20060801 |
| Post-transplant de novo malignancies in renal transplant recipients: the past and present. | Transplant international : official journal of the European Society for Organ Transplantation 20060801 |
| Complementary effects of sirolimus-eluting stents and glycoprotein IIb/IIIa inhibitors for percutaneous coronary intervention in diabetic patients: one-year follow up of a single-centre registry. | Heart (British Cardiac Society) 20060801 |
| Conversion from calcineurin inhibitor to sirolimus in pediatric chronic allograft nephropathy. | Pediatric transplantation 20060801 |
| SRL-based immunosuppression vs. CNI minimization in pediatric renal transplant recipients with chronic CNI nephrotoxicity. | Pediatric transplantation 20060801 |
| Comparison of bare metal stents versus drug-eluting stents on clinical decision making in patients with previous percutaneous coronary intervention admitted for suspected acute coronary syndrome. | The American journal of cardiology 20060801 |
| Frequency of and risk factors for stent thrombosis after drug-eluting stent implantation during long-term follow-up. | The American journal of cardiology 20060801 |
| Impact of sirolimus-eluting and Paclitaxel-eluting stents on outcome in patients with diabetes mellitus and stenting in more than one coronary artery. | The American journal of cardiology 20060801 |
| Neointima inhibition: comparison of effectiveness of non-stent-based local drug delivery and a drug-eluting stent in porcine coronary arteries. | Radiology 20060801 |
| Documented subacute stent thrombosis within thirty days after stenting with sirolimus-eluting stent (Cypher) for acute myocardial infarction: a Japanese single center retrospective non-randomized study. | Circulation journal : official journal of the Japanese Circulation Society 20060801 |
| Immunosuppression using the mTOR inhibition mechanism affects replacement of rat liver with transplanted cells. | Hepatology (Baltimore, Md.) 20060801 |
| Everolimus alters imatinib blood partition in favour of the erythrocyte. | The Journal of pharmacy and pharmacology 20060801 |
| Sustained intraocular rapamycin delivery effectively prevents high-risk corneal allograft rejection and neovascularization in rabbits. | Investigative ophthalmology & visual science 20060801 |
| Frequency and determinants of black holes in sirolimus-eluting stent restenosis. | The Journal of invasive cardiology 20060801 |
| Inhibition of mTOR reduces chronic pressure-overload cardiac hypertrophy and fibrosis. | Journal of hypertension 20060801 |
| Identification of direct and indirect targets of the Gln3 and Gat1 activators by transcriptional profiling in response to nitrogen availability in the short and long term. | FEMS yeast research 20060801 |
| Sirolimus-eluting stent in chronic total occlusion: the SICTO study. | Journal of interventional cardiology 20060801 |
| Clinical and angiographic follow-up after coronary drug-eluting and bare metal stent implantation. Do drug-eluting stents hold the promise? | Journal of internal medicine 20060801 |
| Late-onset invasive aspergillosis in organ transplant recipients in the current era. | Medical mycology 20060801 |
| Determinants of sensitivity and resistance to rapamycin-chemotherapy drug combinations in vivo. | Cancer research 20060801 |
| Sensitive, high throughput HPLC-MS/MS method with on-line sample clean-up for everolimus measurement. | Therapeutic drug monitoring 20060801 |
| Proteomic analysis of anti-angiogenic effects by a combined treatment with vinblastine and rapamycin in an endothelial cell line. | Proteomics 20060801 |
| Reverse diastolic intrarenal flow due to calcineurin inhibitor (CNI) toxicity. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060801 |
| Prolactin activates mammalian target-of-rapamycin through phosphatidylinositol 3-kinase and stimulates phosphorylation of p70S6K and 4E-binding protein-1 in lymphoma cells. | The Journal of endocrinology 20060801 |
| An in vivo platform for translational drug development in pancreatic cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060801 |
| Intracellular signaling in tumor and endothelial cells: The expected and, yet again, the unexpected. | Cancer cell 20060801 |
| The TSC2/mTOR pathway drives endothelial cell transformation induced by the Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor. | Cancer cell 20060801 |
| Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin. | Cancer cell 20060801 |
| New hope for RCC patients. | European journal of cancer (Oxford, England : 1990) 20060801 |
| Alleviation of renal and pulmonary injury by immunomodulation in leptospirosis: hamster model. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20060801 |
| Thyroid hormone stimulates protein synthesis in the cardiomyocyte by activating the Akt-mTOR and p70S6K pathways. | The Journal of biological chemistry 20060728 |
| Effect of rapamycin on hepatic osteodystrophy in rats with portasystemic shunting. | World journal of gastroenterology 20060728 |
| Cost analysis from two randomized trials of sirolimus-eluting stents versus paclitaxel-eluting stents in high-risk patients with coronary artery disease. | Journal of the American College of Cardiology 20060718 |
| Effectiveness and safety of sirolimus stent implantation for coronary in-stent restenosis: the TRUE (Tuscany Registry of Sirolimus for Unselected In-Stent Restenosis) Registry. | Journal of the American College of Cardiology 20060718 |
| Rapamycin-mediated enrichment of T cells with regulatory activity in stimulated CD4+ T cell cultures is not due to the selective expansion of naturally occurring regulatory T cells but to the induction of regulatory functions in conventional CD4+ T cells. | Journal of immunology (Baltimore, Md. : 1950) 20060715 |
| Sirolimus-eluting stents versus Paclitaxel-eluting stents in the treatment of coronary artery disease in patients with diabetes mellitus. | The American journal of cardiology 20060715 |
| Rapamycin delays but does not prevent recovery from acute renal failure: role of acquired tubular resistance. | Transplantation 20060715 |
| Stimulation of the intestinal phosphate transporter SLC34A2 by the protein kinase mTOR. | Biochemical and biophysical research communications 20060714 |
| Trials probe new agents for kidney cancer. | JAMA 20060712 |
| A comparison of angiographic and clinical outcomes after sirolimus-eluting versus paclitaxel-eluting stents for the treatment of in-stent restenosis. | Chinese medical journal 20060705 |
| Periprocedural and late consequences of overlapping Cypher sirolimus-eluting stents: pooled analysis of five clinical trials. | Journal of the American College of Cardiology 20060704 |
| Rapid decline of collateral circulation increases susceptibility to myocardial ischemia: the trade-off of successful percutaneous recanalization of chronic total occlusions. | Journal of the American College of Cardiology 20060704 |
| Pathology of drug-eluting stents in humans: delayed healing and late thrombotic risk. | Journal of the American College of Cardiology 20060704 |
| Drug-eluting stent thrombosis: increasingly recognized but too frequently overemphasized. | Journal of the American College of Cardiology 20060704 |
| Role of endothelin-1 and nitric oxide bioavailability in transplant-related vascular injury: comparative effects of rapamycin and cyclosporine. | Circulation 20060704 |
| Post-transplantation anaemia in adult and paediatric renal allograft recipients-Guy's Hospital experience. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701 |
| Bioluminescence imaging after HSV amplicon vector delivery into brain. | The journal of gene medicine 20060701 |
| Podospora anserina target of rapamycin. | Current genetics 20060701 |
| Comparative effects of paclitaxel and rapamycin on smooth muscle migration and survival: role of AKT-dependent signaling. | Arteriosclerosis, thrombosis, and vascular biology 20060701 |
| Query Chem: a Google-powered web search combining text and chemical structures. | Bioinformatics (Oxford, England) 20060701 |
| A patient recently transplanted with a living donor kidney develops severe neurological symptoms. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701 |
| Mammalian target of rapamycin inhibitors in sarcomas. | Current opinion in oncology 20060701 |
| Evaluation of a fluorescent polarization immunoassay for whole blood everolimus determination using samples from renal transplant recipients. | Clinical biochemistry 20060701 |
| Conversion from calcineurin inhibitor to sirolimus for renal function deterioration in kidney allograft recipients. | Archives of medical research 20060701 |
| alpha-lipoic acid regulates AMP-activated protein kinase and inhibits insulin secretion from beta cells. | Diabetologia 20060701 |
| Impact of three or more sirolimus-eluting stents versus paclitaxel-eluting stents on clinical outcomes in patients undergoing percutaneous coronary intervention. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701 |
| Experimental efficacy of an everolimus eluting cobalt chromium stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701 |
| Very late thrombosis after drug-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060701 |
| Effects of tacrolimus, cyclosporin A and sirolimus on MG63 cells. | Transplant international : official journal of the European Society for Organ Transplantation 20060701 |
| Sudden hearing loss associated with tacrolimus in a liver transplant recipient. | Transplant international : official journal of the European Society for Organ Transplantation 20060701 |
| Acne in recipients of renal transplantation treated with sirolimus: clinical, microbiologic, histologic, therapeutic, and pathogenic aspects. | Journal of the American Academy of Dermatology 20060701 |
| Sirolimus-eluting stents at two years: a pooled analysis of SIRIUS, E-SIRIUS, and C-SIRIUS with emphasis on late revascularizations and stent thromboses. | The American journal of cardiology 20060701 |
| Effects of cyclosporin A, FK506 and rapamycin on calcineurin phosphatase activity in mouse brain. | IUBMB life 20060701 |
| Everolimus: an immunosuppressive agent in transplantation. | Expert opinion on pharmacotherapy 20060701 |
| Risk factors for impaired health status differ in women and men treated with percutaneous coronary intervention in the drug-eluting stent era. | Journal of psychosomatic research 20060701 |
| CYP3A5*3 influences sirolimus oral clearance in de novo and stable renal transplant recipients. | Clinical pharmacology and therapeutics 20060701 |
| Potential role of proliferation signal inhibitors on atherosclerosis in renal transplant patients. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701 |
| Everolimus in clinical practice--renal transplantation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701 |
| Conversion to everolimus in maintenance patients--current clinical strategies. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701 |
| Conversion to a proliferation signal inhibitor in a patient with coronary artery disease--a case report. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701 |
| Conversion to everolimus in a patient with arterial hypertension and recurrent cutaneous neoplasia--a case report. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701 |
| Long-term cardiovascular risk in transplantation--insights from the use of everolimus in heart transplantation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060701 |
| Sirolimus-induced pneumonitis presenting as acute respiratory distress syndrome. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060701 |
| Activation of mammalian target of rapamycin signaling pathway contributes to tumor cell survival in anaplastic lymphoma kinase-positive anaplastic large cell lymphoma. | Cancer research 20060701 |
| Tacrolimus and sirolimus: when bad things happen to good drugs. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060701 |
| Long-term renal allograft function on a tacrolimus-based, pred-free maintenance immunosuppression comparing sirolimus vs. MMF. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060701 |
| Regulation of mTOR by mechanically induced signaling events in skeletal muscle. | Cell cycle (Georgetown, Tex.) 20060701 |
| Inhibition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in hematologic malignancies. | Current treatment options in oncology 20060701 |
| Coronary artery restenosis: vascular biology and emerging therapeutic strategies. | Expert review of cardiovascular therapy 20060701 |
| [Inhibition of growth and metastasis of hepatocellular carcinoma by rapamycin: experiment with mice]. | Zhonghua yi xue za zhi 20060627 |
| [Local applied slow-releasing rapamycin inhibits neointima hyperplasia in vein graft]. | Zhonghua yi xue za zhi 20060627 |
| The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity. | The EMBO journal 20060621 |
| PTEN takes center stage in cancer stem cell research, works as tumor suppressor. | Journal of the National Cancer Institute 20060621 |
| Prevalence, predictors, and outcomes of premature discontinuation of thienopyridine therapy after drug-eluting stent placement: results from the PREMIER registry. | Circulation 20060620 |
| Drug-eluting stent restenosis the pattern predicts the outcome. | Journal of the American College of Cardiology 20060620 |
| Narrative review: drug-eluting stents for the management of restenosis: a critical appraisal of the evidence. | Annals of internal medicine 20060620 |
| A role for the mTOR pathway in surface expression of AMPA receptors. | Neuroscience letters 20060619 |
| Activation of the mTOR signalling pathway is required for pancreatic growth in protease-inhibitor-fed mice. | The Journal of physiology 20060615 |
| Images in cardiovascular medicine. Severe endothelial dysfunction after sirolimus-eluting stent implantation. | Circulation 20060613 |
| [Diffuse lung diseases]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20060610 |
| General repression of RNA polymerase III transcription is triggered by protein phosphatase type 2A-mediated dephosphorylation of Maf1. | Molecular cell 20060609 |
| Evaluation of rapamycin chemical stability in volatile-organic solvents by HPLC. | Journal of pharmaceutical and biomedical analysis 20060607 |
| A randomized comparison of sirolimus-eluting stent with balloon angioplasty in patients with in-stent restenosis: results of the Restenosis Intrastent: Balloon Angioplasty Versus Elective Sirolimus-Eluting Stenting (RIBS-II) trial. | Journal of the American College of Cardiology 20060606 |
| Vascular effects of sirolimus-eluting versus bare-metal stents in diabetic patients: three-dimensional ultrasound results of the Diabetes and Sirolimus-Eluting Stent (DIABETES) Trial. | Journal of the American College of Cardiology 20060606 |
| Zotarolimus (ABT-578) eluting stents. | Advanced drug delivery reviews 20060603 |
| Clinical experience and applications of drug-eluting stents in the noncoronary vasculature, bile duct and esophagus. | Advanced drug delivery reviews 20060603 |
| Countervailing effects of rapamycin (sirolimus) on nuclear factor-kappa B activities in neointimal and medial smooth muscle cells. | Atherosclerosis 20060601 |
| Sirolimus-eluting stent fracture with thrombus, visualization by optical coherence tomography. | European heart journal 20060601 |
| Insulin-facilitated increase of muscle protein synthesis after resistance exercise involves a MAP kinase pathway. | American journal of physiology. Endocrinology and metabolism 20060601 |
| Rapamycin antagonizes NF-kappaB nuclear translocation activated by TNF-alpha in primary vascular smooth muscle cells and enhances apoptosis. | American journal of physiology. Heart and circulatory physiology 20060601 |
| Increase in S6K1 phosphorylation in human skeletal muscle following resistance exercise occurs mainly in type II muscle fibers. | American journal of physiology. Endocrinology and metabolism 20060601 |
| Insulin and oxidative stress modulate proliferation of rat ovarian theca-interstitial cells through diverse signal transduction pathways. | Biology of reproduction 20060601 |
| Effect of severe short-term malnutrition on diaphragm muscle signal transduction pathways influencing protein turnover. | Journal of applied physiology (Bethesda, Md. : 1985) 20060601 |
| Bifurcation stenting with drug eluting stents: illustration of the crush technique. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060601 |
| Intravascular ultrasound predictors of angiographic restenosis after sirolimus-eluting stent implantation. | European heart journal 20060601 |
| 'Head-to-head comparison between sirolimus-eluting and paclitaxel-eluting stents in patients with complex coronary artery disease: an intravascular ultrasound study'. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060601 |
| Rapamycin induces a caspase-independent cell death in human monocytes. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060601 |
| Tacrolimus with mycophenolate mofetil (MMF) or sirolimus vs. cyclosporine with MMF in cardiac transplant patients: 1-year report. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060601 |
| Everolimus and reduced cyclosporine trough levels in maintenance heart transplant recipients. | Transplant immunology 20060601 |
| Recent developments in targeting the mammalian target of rapamycin (mTOR) kinase pathway. | Anti-cancer drugs 20060601 |
| Conversion from calcineurin inhibitor to sirolimus in pediatric chronic allograft nephropathy. | Pediatric transplantation 20060601 |
| Rapamycin, an mTOR inhibitor, disrupts triglyceride metabolism in guinea pigs. | Metabolism: clinical and experimental 20060601 |
| Very late thrombosis after sirolimus-eluting stent implantation. | Journal of cardiovascular medicine (Hagerstown, Md.) 20060601 |
| A meta-analysis of trials comparing Cypher and Taxus stents in patients with obstructive coronary artery disease. | British journal of clinical pharmacology 20060601 |
| Rapamycin and chronic kidney disease: beyond the inhibition of inflammation. | Kidney international 20060601 |
| The fate of patients with clinical recurrence after sirolimus-eluting stent implantation (a two-year follow-up analysis from the SIRIUS trial). | The American journal of cardiology 20060601 |
| Overcoming T cell-mediated rejection of bone marrow allografts by T-regulatory cells: synergism with veto cells and rapamycin. | Experimental hematology 20060601 |
| The incidence of acute cellular rejection after lung transplantation: a comparative study of anti-thymocyte globulin and daclizumab. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060601 |
| Sirolimus for Kaposi's sarcoma. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060601 |
| Induction of tolerance in type 1 diabetes via both CD4+CD25+ T regulatory cells and T regulatory type 1 cells. | Diabetes 20060601 |
| Rapamycin attenuates unilateral ureteral obstruction-induced renal fibrosis. | Kidney international 20060601 |
| Antiangiogenic potential of the Mammalian target of rapamycin inhibitor temsirolimus. | Cancer research 20060601 |
| Perspectives in central nervous system malignancies. | IDrugs : the investigational drugs journal 20060601 |
| Antilymphoid antibody preconditioning and tacrolimus monotherapy for pediatric kidney transplantation. | The Journal of pediatrics 20060601 |
| Solitary pancreas transplantation for life-threatening allergy to human insulin. | Transplant international : official journal of the European Society for Organ Transplantation 20060601 |
| Percutaneous stenting of the left main with drug eluting stents for in-stent restenosis: immediate- and long-term results. | The Journal of invasive cardiology 20060601 |
| Sirolimus-induced pulmonary hypersensitivity associated with a CD4 T-cell infiltrate. | Chest 20060601 |
| Drug-eluting stents for infrainguinal occlusive disease: progress and challenges. | Seminars in vascular surgery 20060601 |
| Targeting mTOR for cancer treatment. | Current opinion in investigational drugs (London, England : 2000) 20060601 |
| Conversion from calcineurin inhibitors to sirolimus in patients with chronic renal allograft dysfunction. | Transplantation proceedings 20060601 |
| Sirolimus-induced intractable chronic diarrhea: a case report. | Transplantation proceedings 20060601 |
| New therapies in the treatment of breast cancer. | Seminars in oncology 20060601 |
| Molecular targeting therapy for renal cell carcinoma. | International journal of clinical oncology 20060601 |
| A comparison of measured trough levels and abbreviated AUC estimation by limited sampling strategies for monitoring mycophenolic acid exposure in stable heart transplant patients receiving cyclosporin A-containing and cyclosporin A-free immunosuppressive regimens. | Clinical therapeutics 20060601 |
| Switching immunosuppressive drugs in kidney transplant recipients: 'show me the evidence'. | Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia 20060601 |
| No effect of sirolimus for kaposi sarcoma in a renal transplant recipient. | Transplantation 20060527 |
| Autophagy: is it cancer's friend or foe? | Science (New York, N.Y.) 20060526 |
| Pten dependence distinguishes haematopoietic stem cells from leukaemia-initiating cells. | Nature 20060525 |
| Functional genomics identifies TOR-regulated genes that control growth and division. | Current biology : CB 20060523 |
| Conversion to sirolimus immunosuppression in liver transplantation recipients with hepatocellular carcinoma: Report of an initial experience. | World journal of gastroenterology 20060521 |
| Predictive factors of restenosis after coronary implantation of sirolimus- or paclitaxel-eluting stents. | Circulation 20060516 |
| Long-term outcomes after stenting of bifurcation lesions with the 'crush' technique: predictors of an adverse outcome. | Journal of the American College of Cardiology 20060516 |
| Incomplete neointimal coverage of sirolimus-eluting stents: angioscopic findings. | Journal of the American College of Cardiology 20060516 |
| Target of rapamycin inhibitors (sirolimus and everolimus) for primary immunosuppression of kidney transplant recipients: a systematic review and meta-analysis of randomized trials. | Transplantation 20060515 |
| Stm1p, a ribosome-associated protein, is important for protein synthesis in Saccharomyces cerevisiae under nutritional stress conditions. | Journal of molecular biology 20060512 |
| Neuroscience. Regulating energy balance: the substrate strikes back. | Science (New York, N.Y.) 20060512 |
| Hypothalamic mTOR signaling regulates food intake. | Science (New York, N.Y.) 20060512 |
| Predictive factors of cardiac events after implantation of sirolimus-eluting stents for treatment of in-stent restenosis. | International journal of cardiology 20060510 |
| Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20060503 |
| Life-threatening coronary artery spasm following sirolimus-eluting stent deployment. | Journal of the American College of Cardiology 20060502 |
| Endothelial dysfunction after drug-eluting stent was never predicted in preclinical studies. | Journal of the American College of Cardiology 20060502 |
| Limitations of crush technique. | Journal of the American College of Cardiology 20060502 |
| Drug eluting stents: an updated meta-analysis of randomised controlled trials. | Heart (British Cardiac Society) 20060501 |
| Late coronary thrombosis in a sirolimus-eluting stent due to the lack of neointimal coverage. | European heart journal 20060501 |
| Efficacy of drug eluting stents in patients with and without diabetes mellitus: indirect comparison of controlled trials. | Heart (British Cardiac Society) 20060501 |
| In vivo antitumor effect of the mTOR inhibitor CCI-779 and gemcitabine in xenograft models of human pancreatic cancer. | International journal of cancer 20060501 |
| Abnormal growth of smooth muscle-like cells in lymphangioleiomyomatosis: Role for tumor suppressor TSC2. | American journal of respiratory cell and molecular biology 20060501 |
| Interferon-gamma-induced dephosphorylation of STAT3 and apoptosis are dependent on the mTOR pathway. | Experimental cell research 20060501 |
| Role of drug eluting stents in diabetic patients. | Heart (British Cardiac Society) 20060501 |
| Drug-eluting stents studies in mice: do we need atherosclerosis to study restenosis? | Vascular pharmacology 20060501 |
| Inhibition of the mammalian target of rapamycin (mTOR) by rapamycin increases chemosensitivity of CaSki cells to paclitaxel. | European journal of cancer (Oxford, England : 1990) 20060501 |
| Locally administered antiproliferative drugs inhibit hypercontractility to serotonin in balloon-injured pig coronary artery. | Vascular pharmacology 20060501 |
| Differentiation of innovator versus generic cyclosporine via a drug interaction on sirolimus. | European journal of clinical pharmacology 20060501 |
| Mammalian target of rapamycin pathway blockade slows progression of diabetic kidney disease in rats. | Journal of the American Society of Nephrology : JASN 20060501 |
| Wound healing complications with de novo sirolimus versus mycophenolate mofetil-based regimen in cardiac transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060501 |
| Sequential kidney/islet transplantation: efficacy and safety assessment of a steroid-free immunosuppression protocol. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060501 |
| Colonic perforation associated with leukocytoclastic vasculitis caused by Sirolimus toxicity following renal transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20060501 |
| Sirolimus-induced remission of posttransplantation lymphoproliferative disorder. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20060501 |
| Comparison of safety and efficacy of sirolimus-eluting stents versus bare metal stents in patients with ST-segment elevation myocardial infarction. | The American journal of cardiology 20060501 |
| C-Reactive protein, clinical outcome, and restenosis rates after implantation of different drug-eluting stents. | The American journal of cardiology 20060501 |
| A prospective registry to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions using the 'crush technique'. | The American journal of cardiology 20060501 |
| Voriconazole and sirolimus coadministration after allogeneic hematopoietic stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20060501 |
| Sirolimus-eluting coronary stents in small vessels. | American heart journal 20060501 |
| Survival signaling by Notch1: mammalian target of rapamycin (mTOR)-dependent inhibition of p53. | Cancer research 20060501 |
| Everolimus (RAD) inhibits in vivo growth of murine squamous cell carcinoma (SCC VII). | The Laryngoscope 20060501 |
| Comparison between sirolimus- and Paclitaxel-eluting stents for the treatment of chronic total occlusions. | The Journal of invasive cardiology 20060501 |
| Sirolimus or paclitaxel drug-eluting stents for treatment of chronic total occlusions of coronary arteries: much ado about very little. | The Journal of invasive cardiology 20060501 |
| Sirolimus rescue for tacrolimus-associated post-transplant autoimmune hemolytic anemia. | Pediatric transplantation 20060501 |
| Early renal benefit of rapamycin combined with reduced calcineurin inhibitor dose in pediatric heart transplantation patients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060501 |
| Integrated coronary revascularization with drug-eluting stents: immediate and seven-month outcome. | The Journal of thoracic and cardiovascular surgery 20060501 |
| Autophagy: A protective mechanism in response to stress and inflammation. | Current opinion in investigational drugs (London, England : 2000) 20060501 |
| Targeting the Akt/mammalian target of rapamycin pathway for radiosensitization of breast cancer. | Molecular cancer therapeutics 20060501 |
| Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells. | Molecular cancer therapeutics 20060501 |
| Possible molecular target therapy with rapamycin in MDS. | Leukemia & lymphoma 20060501 |
| Cutaneous leukocytoclastic vasculitis in a patient with myelodysplastic syndrome after therapy with the rapamycin analogue everolimus: case report and review of the literature. | Leukemia & lymphoma 20060501 |
| Drug eluting stents: data from a clinical registry. | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20060501 |
| Long-term results of kidney transplantation with cyclosporine- and everolimus-based immunosuppression. | Transplantation proceedings 20060501 |
| Incidence of posttransplant diabetes mellitus in kidney transplant recipients immunosuppressed with sirolimus in combination with cyclosporine. | Transplantation proceedings 20060501 |
| Lymphocele after renal transplantation: the influence of the immunosuppressive therapy. | Transplantation proceedings 20060501 |
| [Effects of rapamycin on Rho-kinase and p27 mRNA expressions in a porcine coronary intimal proliferation model induced by interleukin-1beta]. | Zhonghua xin xue guan bing za zhi 20060501 |
| mTOR, Akt, S6 kinases and the control of skeletal muscle growth. | Bulletin du cancer 20060501 |
| [The PI3K/Akt/mTOR pathway: a new therapeutic target in the treatment of acute myeloid leukemia]. | Bulletin du cancer 20060501 |
| CCI-779 inhibits rhabdomyosarcoma xenograft growth by an antiangiogenic mechanism linked to the targeting of mTOR/Hif-1alpha/VEGF signaling. | Neoplasia (New York, N.Y.) 20060501 |
| Sirolimus early graft nephrotoxicity: clinical and experimental data. | Current drug safety 20060501 |
| Inhibition of corneal neovascularization by rapamycin. | Experimental & molecular medicine 20060430 |
| Pancreas transplantation utilizing thymoglobulin, sirolimus, and cyclosporine. | Transplantation 20060427 |
| GATA factor translation is the final downstream step in the amino acid/target-of-rapamycin-mediated vitellogenin gene expression in the anautogenous mosquito Aedes aegypti. | The Journal of biological chemistry 20060421 |
| Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB. | Molecular cell 20060421 |
| mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin. | The EMBO journal 20060419 |
| Target of rapamycin inhibitors (TOR-I; sirolimus and everolimus) for primary immunosuppression in kidney transplant recipients. | The Cochrane database of systematic reviews 20060419 |
| Oral rapamycin after coronary bare-metal stent implantation to prevent restenosis: the Prospective, Randomized Oral Rapamycin in Argentina (ORAR II) Study. | Journal of the American College of Cardiology 20060418 |
| Distal left main coronary disease is a major predictor of outcome in patients undergoing percutaneous intervention in the drug-eluting stent era: an integrated clinical and angiographic analysis based on the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) and Taxus-Stent Evaluated At Rotterdam Cardiology Hospital (T-SEARCH) registries. | Journal of the American College of Cardiology 20060418 |
| Mechanical stimuli and nutrients regulate rapamycin-sensitive signaling through distinct mechanisms in skeletal muscle. | Journal of cellular biochemistry 20060415 |
| SUMO modification through rapamycin-mediated heterodimerization reveals a dual role for Ubc9 in targeting RanGAP1 to nuclear pore complexes. | Experimental cell research 20060415 |
| Improved renal function after conversion from tacrolimus/sirolimus to tacrolimus/mycophenolate mofetil in kidney transplant recipients. | Transplantation 20060415 |
| Comparison of sirolimus versus paclitaxel eluting stents for treatment of coronary in-stent restenosis. | The American journal of cardiology 20060415 |
| Usefulness and safety of percutaneous coronary interventions for cardiac transplant vasculopathy. | The American journal of cardiology 20060415 |
| Rapamycin inhibits growth of premalignant and malignant mammary lesions in a mouse model of ductal carcinoma in situ. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060415 |
| [Drug-eluting stents: do they keep their promises?]. | Praxis 20060412 |
| Outcomes of using Firebird rapamycin eluting stents in routine coronary intervention practice: one-year results from the pilot study of Firebird in China registry. | Chinese medical journal 20060405 |
| Two-year outcomes after sirolimus-eluting stent implantation: results from the Sirolimus-Eluting Stent in de Novo Native Coronary Lesions (SIRIUS) trial. | Journal of the American College of Cardiology 20060404 |
| Sirolimus-eluting stents remain superior to bare-metal stents at two years: medium-term results from the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry. | Journal of the American College of Cardiology 20060404 |
| Drug-eluting stents are safe and effective: right or wrong? | Journal of the American College of Cardiology 20060404 |
| Summaries for patients. Twenty-four cases of pneumonitis in kidney transplantation recipients receiving sirolimus. | Annals of internal medicine 20060404 |
| Brief communication: sirolimus-associated pneumonitis: 24 cases in renal transplant recipients. | Annals of internal medicine 20060404 |
| Identification and characterization of a constitutively T-loop phosphorylated and active recombinant S6K1: expression, purification, and enzymatic studies in a high capacity non-radioactive TR-FRET Lance assay. | Protein expression and purification 20060401 |
| mTOR pathway inhibition attenuates skeletal muscle growth induced by stretching. | Cell and tissue research 20060401 |
| Immunoglobulin G from patients with Graves' disease induces interleukin-16 and RANTES expression in cultured human thyrocytes: a putative mechanism for T-cell infiltration of the thyroid in autoimmune disease. | Endocrinology 20060401 |
| Zotarolimus-eluting stents reduce experimental coronary artery neointimal hyperplasia after 4 weeks. | European heart journal 20060401 |
| Rapamycin pre-treatment protects against apoptosis. | Human molecular genetics 20060401 |
| Impact of overlapping drug-eluting stents in patients undergoing percutaneous coronary intervention. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060401 |
| Prolonged survival of allogeneic islets in cynomolgus monkeys after short-term anti-CD154-based therapy: nonimmunologic graft failure? | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060401 |
| Rapamycin attenuates liver graft injury in cirrhotic recipient--the significance of down-regulation of Rho-ROCK-VEGF pathway. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060401 |
| Effects of rapamycin on number activity and eNOS of endothelial progenitor cells from peripheral blood. | Cell proliferation 20060401 |
| Multi-center evaluation of analytical performance of the microparticle enzyme immunoassay for sirolimus. | Clinical biochemistry 20060401 |
| Comparison of the effectiveness of sirolimus- and paclitaxel-eluting stents for small coronary artery lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060401 |
| Everolimus in pulmonary transplantation: pharmacokinetics and exposure-response relationships. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060401 |
| Acute renal failure in a liver transplant patient after treatment with sirolimus. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20060401 |
| Are drug-eluting stents cost-effective when compared with bare-metal stents in a real-world setting? | Nature clinical practice. Cardiovascular medicine 20060401 |
| Percutaneous transluminal angioplasty for treatment of ''below-the-knee'' critical limb ischemia: early outcomes following the use of sirolimus-eluting stents. | The Journal of cardiovascular surgery 20060401 |
| Simultaneous corticosteroid avoidance and calcineurin inhibitor minimization in renal transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20060401 |
| Sirolimus and FK778: a comparison of two anti-proliferative immunosuppressants for prevention of experimental obliterative airway disease. | Transplant international : official journal of the European Society for Organ Transplantation 20060401 |
| How to revascularize patients with diabetes mellitus: bypass or stents and drugs? | Clinical research in cardiology : official journal of the German Cardiac Society 20060401 |
| Managing the introduction of expensive medical procedures: use of a registry. | Journal of health services research & policy 20060401 |
| [Technical evolution of the stent]. | Nihon rinsho. Japanese journal of clinical medicine 20060401 |
| Comparison of the reintroduced MEIA assay with HPLC-MS/MS for the determination of whole-blood sirolimus from transplant recipients. | Therapeutic drug monitoring 20060401 |
| Determination of mycophenolic acid plasma levels in renal transplant recipients co-administered sirolimus: comparison of an enzyme multiplied immunoassay technique (EMIT) and liquid chromatography-tandem mass spectrometry. | Therapeutic drug monitoring 20060401 |
| Resolution of sirolimus-induced pneumonitis after conversion to everolimus. | Transplantation proceedings 20060401 |
| Side effects of sirolimus. | Transplantation proceedings 20060401 |
| Antiproliferative and overadditive effects of everolimus and mycophenolate mofetil in pancreas and lung cancer cells in vitro. | Transplantation proceedings 20060401 |
| Recommendations for use of everolimus after heart transplantation: results from a Latin-American Consensus Meeting. | Transplantation proceedings 20060401 |
| Efficacy of sirolimus-eluting stents as compared to paclitaxel-eluting stents for saphenous vein graft intervention. | Journal of interventional cardiology 20060401 |
| Two-year follow-up of sirolimus-eluting stents for the treatment of proximal left anterior descending coronary artery stenosis. | Journal of interventional cardiology 20060401 |
| Novel regulatory properties of Saccharomyces cerevisiae Arp4. | Journal of biochemistry 20060401 |
| [Sirolimus-eluting stents for the treatment of stenoses in small coronary arteries: what have we learned?]. | Arquivos brasileiros de cardiologia 20060401 |
| [Comparative analysis of intimal hyperplasia after sirolimus-eluting stent and thin-strut bare-metal stent implantation in small coronary arteries]. | Arquivos brasileiros de cardiologia 20060401 |
| [Molecular targets in colon cancer]. | Therapeutische Umschau. Revue therapeutique 20060401 |
| Long-term follow up after coronary sirolimus drug-eluting stent implantation for cardiac transplant arteriopathy. | The Journal of invasive cardiology 20060401 |
| Long-term follow up of diabetic patients treated with sirolimus-eluting stents. An angiographic and three-dimensional intravascular ultrasound study. | The Journal of invasive cardiology 20060401 |
| Future directions in the treatment of hormone-sensitive advanced breast cancer: the RAD001 (Everolimus)-letrozole clinical program. | Seminars in oncology 20060401 |
| [The femoral artery: the most complex peripheral vessel]. | Herz 20060401 |
| [The impact of expansion of sirolimus eluting stent on intimal hyperplasia: an intravascular ultrasound study]. | Zhonghua xin xue guan bing za zhi 20060401 |
| Future anti-catabolic therapeutic targets in bone disease. | Annals of the New York Academy of Sciences 20060401 |
| A randomized long-term trial of tacrolimus/sirolimus versus tacrolimums/mycophenolate versus cyclosporine/sirolimus in renal transplantation: three-year analysis. | Transplantation 20060327 |
| Stimulation of the creatine transporter SLC6A8 by the protein kinase mTOR. | Biochemical and biophysical research communications 20060324 |
| Successful management of left main coronary artery stenosis with a paclitaxel-eluting stent in Takayasu's arteritis. | International journal of cardiology 20060322 |
| Biosynthesis of pipecolic acid by RapL, a lysine cyclodeaminase encoded in the rapamycin gene cluster. | Journal of the American Chemical Society 20060322 |
| Safety of coronary sirolimus-eluting stents in daily clinical practice: one-year follow-up of the e-Cypher registry. | Circulation 20060321 |
| The role of phospholipase D and phosphatidic acid in the mechanical activation of mTOR signaling in skeletal muscle. | Proceedings of the National Academy of Sciences of the United States of America 20060321 |
| Blockade of CD154-CD40 pathway induces interleukin-10 dependent T regulatory type 1 like cells. | Chinese medical journal 20060320 |
| A nuclear transport signal in mammalian target of rapamycin is critical for its cytoplasmic signaling to S6 kinase 1. | The Journal of biological chemistry 20060317 |
| Mammalian target of rapamycin (mTOR) regulates both proliferation of megakaryocyte progenitors and late stages of megakaryocyte differentiation. | Blood 20060315 |
| Impact of chronic renal insufficiency on clinical outcomes in patients undergoing percutaneous coronary intervention with sirolimus-eluting stents versus bare metal stents. | The American journal of cardiology 20060315 |
| Sirolimus-eluting stents vs vascular brachytherapy for in-stent restenosis within bare-metal stents: the SISR randomized trial. | JAMA 20060315 |
| Brachytherapy for in-stent restenosis: a distant second choice to drug-eluting stent placement. | JAMA 20060315 |
| Switch from calcineurin inhibitors to sirolimus-induced renal recovery in heart transplant recipients in the midterm follow-up. | Transplantation 20060315 |
| An open prospective pilot study on the use of rapamycin after penetrating high-risk keratoplasty. | Transplantation 20060315 |
| New drug application 21-628, Certican (everolimus), for the proposed indication of prophylaxis of rejection in heart transplantation: report from the Cardiovascular and Renal Drugs Advisory Committee, US Food and Drug Administration, November 16, 2005, Rockville, Md. | Circulation 20060314 |
| Clinical islet transplantation in type 1 diabetes mellitus: results of Australia's first trial. | The Medical journal of Australia 20060306 |
| Inhibition of mTOR with sirolimus slows disease progression in Han:SPRD rats with autosomal dominant polycystic kidney disease (ADPKD). | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301 |
| Rapamycin inhibits hTERT telomerase mRNA expression, independent of cell cycle arrest. | Gynecologic oncology 20060301 |
| Molecular activity of sirolimus and its possible application in tuberous sclerosis treatment. | Medicinal research reviews 20060301 |
| Conversion from calcineurin inhibitors to sirolimus in chronic allograft nephropathy: benefits and risks. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301 |
| [Sirolimus-associated interstitial pneumonitis in a renal transplant patient]. | La Revue de medecine interne 20060301 |
| Sirolimus in de novo heart transplant recipients with severe renal impairment. | Transplant international : official journal of the European Society for Organ Transplantation 20060301 |
| Rapamycin causes regression of astrocytomas in tuberous sclerosis complex. | Annals of neurology 20060301 |
| Complete avoidance of calcineurin inhibitors in renal transplantation: a randomized trial comparing sirolimus and tacrolimus. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060301 |
| Tacrolimus combined with two different dosages of sirolimus in kidney transplantation: results of a multicenter study. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060301 |
| Restenosis of a sirolimus drug-eluting stent: aorto-ostial involvement of the proximal right coronary artery. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060301 |
| Novel apoptosis assay to analyze immunosuppression. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060301 |
| Differing responses of Gat1 and Gln3 phosphorylation and localization to rapamycin and methionine sulfoximine treatment in Saccharomyces cerevisiae. | FEMS yeast research 20060301 |
| Drug-eluting stent-supported percutaneous coronary intervention for chronic total coronary occlusion. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060301 |
| Is late luminal loss an accurate predictor of the clinical effectiveness of drug-eluting stents in the coronary arteries? | The American journal of cardiology 20060301 |
| Impact of three or more versus a single sirolimus-eluting stent on outcomes in patients who undergo percutaneous coronary intervention. | The American journal of cardiology 20060301 |
| Percutaneous coronary interventions with stents in cardiac transplant recipients. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060301 |
| Mechanistic insights into achievement of cardiac allograft long-term survival by treatment with immature dendritic cells and sub-dose sirolimus. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060301 |
| Calcium signaling stimulates translation of HIF-alpha during hypoxia. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301 |
| Perspectives in gynecologic oncology -- Third European Conference. | IDrugs : the investigational drugs journal 20060301 |
| Using 'bumps' and 'holes' to control protein activity. | Nature methods 20060301 |
| IRS-1: auditing the effectiveness of mTOR inhibitors. | Cancer cell 20060301 |
| Individualization of immunosuppressive therapy. III. Sirolimus associated with a reduced incidence of malignancy. | Transplantation proceedings 20060301 |
| Cutaneous effects of sirolimus in renal transplant recipients. | Journal of drugs in dermatology : JDD 20060301 |
| [Stroma-targeted palliative tumor therapy with biomodulators]. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20060301 |
| Economic evaluation of drug-eluting stents in Japan. | The Keio journal of medicine 20060301 |
| [Two-year clinical follow-up in 200 patients receiving sirolimus-eluting stents in lesions at a high risk of restenosis]. | Revista espanola de cardiologia 20060301 |
| Correlates and long-term outcomes of angiographically proven stent thrombosis with sirolimus- and paclitaxel-eluting stents. | Circulation 20060227 |
| Human allograft arterial injury is ameliorated by sirolimus and cyclosporine and correlates with suppression of interferon-gamma. | Transplantation 20060227 |
| Tacrolimus-associated optic neuropathy after pancreatic islet transplantation using a sirolimus/tacrolimus immunosuppressive regimen. | Transplantation 20060227 |
| Pregnancy under sirolimus-based immunosuppression. | Transplantation 20060227 |
| Sirolimus- vs paclitaxel-eluting stents in de novo coronary artery lesions: the REALITY trial: a randomized controlled trial. | JAMA 20060222 |
| Wish list and REALITY: choice of stents and end points for treatment of de novo coronary artery lesions. | JAMA 20060222 |
| Sirolimus and Paclitaxel on polymer-based drug-eluting stents: similar but different. | Journal of the American College of Cardiology 20060221 |
| Serial angiographic follow-up of sirolimus-eluting stents for unprotected left main coronary artery revascularization. | Journal of the American College of Cardiology 20060221 |
| Drug-eluting stenting for unprotected left main coronary artery disease: are we ready to replace bypass surgery? | Journal of the American College of Cardiology 20060221 |
| Late stent malapposition and marked positive vessel remodeling after sirolimus-eluting coronary stent implantation. | Chinese medical journal 20060220 |
| Effects of drug combinations on smooth muscle cell proliferation: an isobolographic analysis. | European journal of pharmacology 20060217 |
| In yeast, loss of Hog1 leads to osmosensitivity of autophagy. | The Biochemical journal 20060215 |
| A comparison of sirolimus vs. calcineurin inhibitor-based immunosuppressive therapies in liver transplantation. | Alimentary pharmacology & therapeutics 20060215 |
| Inhibition of TPO-induced MEK or mTOR activity induces opposite effects on the ploidy of human differentiating megakaryocytes. | Journal of cell science 20060215 |
| Comparison between sirolimus- and paclitaxel-eluting stent in T-cell subsets redistribution. | The American journal of cardiology 20060215 |
| Angiographic pattern of restenosis following implantation of overlapping sirolimus-eluting (Cypher) stents. | The American journal of cardiology 20060215 |
| Predictors of restenosis after placement of drug-eluting stents in one or more coronary arteries. | The American journal of cardiology 20060215 |
| Posttransplant diabetes mellitus in kidney transplant recipients receiving calcineurin or mTOR inhibitor drugs. | Transplantation 20060215 |
| Conversion to sirolimus and mycophenolate can attenuate the progression of bronchiolitis obliterans syndrome and improves renal function after lung transplantation. | Transplantation 20060215 |
| Rapamycin does not induce anergy but inhibits expansion and differentiation of alloreactive human T cells. | Transplantation 20060215 |
| Mechanism by which mammalian target of rapamycin inhibitors sensitize multiple myeloma cells to dexamethasone-induced apoptosis. | Cancer research 20060215 |
| Glucose-stimulated DNA synthesis through mammalian target of rapamycin (mTOR) is regulated by KATP channels: effects on cell cycle progression in rodent islets. | The Journal of biological chemistry 20060210 |
| Sirolimus-eluting versus paclitaxel-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: a combined RESEARCH and T-SEARCH long-term analysis. | Journal of the American College of Cardiology 20060207 |
| Regression of cutaneous and gastrointestinal telangiectasia with sirolimus and aspirin in a patient with hereditary hemorrhagic telangiectasia. | Annals of internal medicine 20060207 |
| Inhibition of mTOR signaling with rapamycin attenuates renal hypertrophy in the early diabetic mice. | Biochemical and biophysical research communications 20060203 |
| Coronary-artery stents. | The New England journal of medicine 20060202 |
| Simultaneous determination of everolimus and cyclosporine concentrations by HPLC with ultraviolet detection. | Clinica chimica acta; international journal of clinical chemistry 20060201 |
| The mTOR inhibitor CCI-779 induces apoptosis and inhibits growth in preclinical models of primary adult human ALL. | Blood 20060201 |
| Rapamycin, and not cyclosporin A, preserves the highly suppressive CD27+ subset of human CD4+CD25+ regulatory T cells. | Blood 20060201 |
| Adaptor heat shock protein complex formation regulates trafficking of the asialoglycoprotein receptor. | American journal of physiology. Gastrointestinal and liver physiology 20060201 |
| Conversion from calcineurin inhibitors to sirolimus in chronic allograft dysfunction: changes in glomerular haemodynamics and proteinuria. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060201 |
| The Saccharomyces cerevisiae phosphatase activator RRD1 is required to modulate gene expression in response to rapamycin exposure. | Genetics 20060201 |
| Involvement of multiple phosphatidylinositol 3-kinase-dependent pathways in the persistence of late-phase long term potentiation expression. | Neuroscience 20060201 |
| mTOR and cancer: reason for dancing at the crossroads? | Current opinion in genetics & development 20060201 |
| Rapamycin alleviates toxicity of different aggregate-prone proteins. | Human molecular genetics 20060201 |
| Individualizing combination of two antiproliferative immunosuppressants with pharmacodynamic modeling of stimulated lymphocyte responses. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060201 |
| Prevention of carotid artery restenosis after sirolimus-coated stent implantation in pigs. | Stroke 20060201 |
| Comparison of sirolimus-eluting stent, paclitaxel-eluting stent, and bare metal stent in the treatment of long coronary lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201 |
| Revisiting late loss and neointimal volumetric measurements in a drug-eluting stent trial: analysis from the SPIRIT FIRST trial. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201 |
| Mycotic aneurysms after sirolimus-eluting coronary stenting. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060201 |
| Randomized trial of paclitaxel- and sirolimus-eluting stents in small coronary vessels. | European heart journal 20060201 |
| Microarray-based method for monitoring yeast overexpression strains reveals small-molecule targets in TOR pathway. | Nature chemical biology 20060201 |
| Pharmacokinetics and metabolic disposition of sirolimus in healthy male volunteers after a single oral dose. | Therapeutic drug monitoring 20060201 |
| Sirolimus-associated heavy proteinuria in a renal transplant recipient: evidence for a tubular mechanism. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060201 |
| Update on drug-eluting stents for prevention of restenosis. | Asian cardiovascular & thoracic annals 20060201 |
| Sirolimus- or paclitaxel-eluting stents for coronary artery revascularisation. | Expert opinion on pharmacotherapy 20060201 |
| Sirolimus therapy after early cyclosporine withdrawal reduces the risk for cancer in adult renal transplantation. | Journal of the American Society of Nephrology : JASN 20060201 |
| Role of Erk1/2, p70s6K, and eNOS in isoflurane-induced cardioprotection during early reperfusion in vivo. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20060201 |
| Renal calcium handling after rapamycin conversion in chronic allograft dysfunction. | Transplant international : official journal of the European Society for Organ Transplantation 20060201 |
| Reversible sirolimus-associated pneumonitis after heart transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20060201 |
| Procedural success and 30 day outcomes between CYPHER and TAXUS stent implantation for the treatment of bifurcation lesions--a single-center experience. | The Journal of invasive cardiology 20060201 |
| mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. | Cancer research 20060201 |
| Sirolimus-itraconazole interaction in a hematopoietic stem cell transplant recipient. | Pharmacotherapy 20060201 |
| Phase 1 trial of gefitinib plus sirolimus in adults with recurrent malignant glioma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060201 |
| Percutaneous vascular interventions in the superficial femoral artery. A review. | Minerva cardioangiologica 20060201 |
| TORgeting oncogene addiction for cancer therapy. | Cancer cell 20060201 |
| Sirolimus-versus paclitaxel-eluting stents: a comparison of two consecutive series in routine clinical practice. | Journal of interventional cardiology 20060201 |
| Editorial comment: which is the preferred drug-eluting stent? | Journal of interventional cardiology 20060201 |
| Contemporary treatment of coronary bifurcations with drug-eluting stent: part II. | Journal of interventional cardiology 20060201 |
| TCT 2005 late-breaking trials promise to influence practice patterns. | Journal of interventional cardiology 20060201 |
| [Progress in therapeutic strategy for renal cell carcinoma]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060201 |
| Dutasteride, cantharidin, atopiclair, cetuximab, sirolimus, AC-11 and dimericine reviewed in brief. | Journal of drugs in dermatology : JDD 20060201 |
| Cryptogenic organizing pneumonia associated with Pneumocystis carinii infection and sirolimus therapy in a renal transplant patient. | Australasian radiology 20060201 |
| Safety and long-term efficacy of sirolimus eluting stent in ST-elevation acute myocardial infarction: the REAL (Registro REgionale AngiopLastiche Emilia-Romagna) registry. | Cardiovascular drugs and therapy 20060201 |
| [Insulin-dependent. Rapamycin-resistant?]. | Revista espanola de cardiologia 20060201 |
| [Efficacy of sirolimus-eluting stents in diabetics with complex coronary lesions]. | Revista espanola de cardiologia 20060201 |
| [Comparison of Rapamycin and Paclitaxel eluting stent in patients with multi-vessel coronary disease]. | Zhonghua xin xue guan bing za zhi 20060201 |
| [Coronary artery atherosclerotic plaque and stent visualizations by optical coherence tomography]. | Zhonghua xin xue guan bing za zhi 20060201 |
| [Effect of inhibitors of signal transducer and activator of transcription-1/3 on expression of tumor necrosis factor-alpha induced by high mobility group box-1 protein inflammatory response in rat peritoneal macrophages]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20060201 |
| Targeting mTOR signaling for lung cancer therapy. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20060201 |
| mTOR signaling: implications for cancer and anticancer therapy. | British journal of cancer 20060130 |
| Delayed strut fracture of sirolimus-eluting stent: a significant problem or an occasional observation? | International journal of cardiology 20060126 |
| Late stent malapposition after drug-eluting stent implantation: an intravascular ultrasound analysis with long-term follow-up. | Circulation 20060124 |
| One-year clinical outcomes of Chinese sirolimus-eluting stent in the treatment of unselected patients with coronary artery disease. | Chinese medical journal 20060120 |
| Randomized trial of a nonpolymer-based rapamycin-eluting stent versus a polymer-based paclitaxel-eluting stent for the reduction of late lumen loss. | Circulation 20060117 |
| The Stenting Coronary Arteries in Non-stress/benestent Disease (SCANDSTENT) trial. | Journal of the American College of Cardiology 20060117 |
| Hamartin, the tuberous sclerosis complex 1 gene product, interacts with polo-like kinase 1 in a phosphorylation-dependent manner. | Human molecular genetics 20060115 |
| Thrombotic microangiopathy after lung transplantation. | Transplantation 20060115 |
| Rapamycin prolongs susceptibility of responding T cells to tolerance induction by CD8+ veto cells. | Transplantation 20060115 |
| Effect of rapamycin on mouse chronic lymphocytic leukemia and the development of nonhematopoietic malignancies in Emu-TCL1 transgenic mice. | Cancer research 20060115 |
| Rapamycin disrupts cyclin/cyclin-dependent kinase/p21/proliferating cell nuclear antigen complexes and cyclin D1 reverses rapamycin action by stabilizing these complexes. | Cancer research 20060115 |
| Early outcome of treatment of ostial de novo left anterior descending coronary artery lesions with drug-eluting stents. | The American journal of cardiology 20060115 |
| Intravascular ultrasound characterization of the 'black hole' phenomenon after drug-eluting stent implantation. | The American journal of cardiology 20060115 |
| Novel roles of Akt and mTOR in suppressing TGF-beta/ALK5-mediated Smad3 activation. | The EMBO journal 20060111 |
| In vitro release of the mTOR inhibitor rapamycin from poly(ethylene glycol)-b-poly(epsilon-caprolactone) micelles. | Journal of controlled release : official journal of the Controlled Release Society 20060110 |
| Phosphoinositide 3-kinase: from viral oncoprotein to drug target. | Virology 20060105 |
| Comparison of short- and mid-term outcomes between CYPHER and TAXUS stents in patients with complex lesions of the coronary arteries. | Chinese medical journal 20060105 |
| Thrombosis after implantation of drug-eluting stents. | JAMA 20060104 |
| Are drug-eluting stents the preferred treatment for multivessel coronary artery disease? | Journal of the American College of Cardiology 20060103 |
| Hypersensitivity cases associated with drug-eluting coronary stents: a review of available cases from the Research on Adverse Drug Events and Reports (RADAR) project. | Journal of the American College of Cardiology 20060103 |
| Allergic reactions after the implantation of drug-eluting stents: is it the pill or the polymer? | Journal of the American College of Cardiology 20060103 |
| Coronary stent thrombosis in the current drug-eluting stent era: insights from the ERACI III trial. | Journal of the American College of Cardiology 20060103 |
| Drug-eluting stent thrombosis: a pooled analysis. | Journal of the American College of Cardiology 20060103 |
| Cost effectiveness of drug eluting coronary artery stenting in a UK setting: cost-utility study. | Heart (British Cardiac Society) 20060101 |
| N-acetyl-cysteine abolishes hydrogen peroxide-induced modification of eukaryotic initiation factor 4F activity via distinct signalling pathways. | Cellular signalling 20060101 |
| Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells. | International journal of cancer 20060101 |
| Early elevation of interleukin-1beta and interleukin-6 levels after bare or drug-eluting stent implantation in patients with stable angina. | Thrombosis research 20060101 |
| Mammalian target of rapamycin is required for thrombopoietin-induced proliferation of megakaryocyte progenitors. | Stem cells (Dayton, Ohio) 20060101 |
| Dimerizer regulation of AADC expression and behavioral response in AAV-transduced 6-OHDA lesioned rats. | Molecular therapy : the journal of the American Society of Gene Therapy 20060101 |
| Patterns of pulmonary complications associated with sirolimus. | Respiration; international review of thoracic diseases 20060101 |
| Rapamycin control of transgene expression from a single AAV vector in mouse salivary glands. | Gene therapy 20060101 |
| Social inhibition modulates the effect of negative emotions on cardiac prognosis following percutaneous coronary intervention in the drug-eluting stent era. | European heart journal 20060101 |
| Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation. | European heart journal 20060101 |
| Coronary endothelial dysfunction following sirolimus-eluting stent placement: should we worry about it? | European heart journal 20060101 |
| Sirolimus PK trial: a pharmacokinetic study of the sirolimus-eluting Bx velocity stent in patients with de novo coronary lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20060101 |
| Heme oxygenase-1 mediates the protective effects of rapamycin in monocrotaline-induced pulmonary hypertension. | Laboratory investigation; a journal of technical methods and pathology 20060101 |
| Marked erythrocyte microcytosis under primary immunosuppression with sirolimus. | Transplant international : official journal of the European Society for Organ Transplantation 20060101 |
| Cardiac transplantation without calcineurin inhibitors. Sirolimus as first immunosuppressive line. Based on one case. | Transplant international : official journal of the European Society for Organ Transplantation 20060101 |
| Images in cardiology. Acute recoil in sirolimus eluting stent: real time, in vivo assessment with optical coherence tomography. | Heart (British Cardiac Society) 20060101 |
| From Rapa Nui to rapamycin: targeting PI3K/Akt/mTOR for cancer therapy. | Expert review of anticancer therapy 20060101 |
| Efficacy of sirolimus-eluting stents compared with bare metal stents for saphenous vein graft intervention. | The American journal of cardiology 20060101 |
| Natural killer T-cells participate in rejection of islet allografts in the liver of mice. | Diabetes 20060101 |
| Rapamycin and interleukin-10 treatment induces T regulatory type 1 cells that mediate antigen-specific transplantation tolerance. | Diabetes 20060101 |
| Atrophic remodeling of the transplanted rat heart. | Cardiology 20060101 |
| Fibronectin stimulates non-small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of LKB1/AMP-activated protein kinase signal pathways. | Cancer research 20060101 |
| A comparative study of sirolimus tablet versus oral solution for prophylaxis of acute renal allograft rejection. | Journal of clinical pharmacology 20060101 |
| Relationship of cyclosporin and sirolimus blood concentrations regarding the incidence and severity of hyperlipidemia after kidney transplantation. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20060101 |
| One year follow-up of sirolimus-eluting stent in a cardiac post-transplant patient. | The Journal of invasive cardiology 20060101 |
| Kidney cancer: identification of novel targets for therapy. | Kidney international 20060101 |
| Synergistic suppression of rat neointimal hyperplasia by rapamycin and imatinib mesylate: implications for the prevention of accelerated arteriosclerosis. | Journal of vascular research 20060101 |
| Structure-activity relationship for noncoplanar polychlorinated biphenyl congeners toward the ryanodine receptor-Ca2+ channel complex type 1 (RyR1). | Chemical research in toxicology 20060101 |
| Hypoxia-inducible factor-1alpha polymorphisms and TSC1/2 mutations are complementary in head and neck cancers. | Molecular cancer 20060101 |
| Tolerance induction by third-party 'off-the-shelf' CD4+CD25+ Treg cells. | Experimental hematology 20060101 |
| Accounting for strain-specific differences during RTG target gene regulation in Saccharomyces cerevisiae. | FEMS yeast research 20060101 |
| Rapamycin analogs with differential binding specificity permit orthogonal control of protein activity. | Chemistry & biology 20060101 |
| Apoptosis of allospecifically activated human helper T cells is blocked by calcineurin inhibition. | Transplant immunology 20060101 |
| Everolimus versus azathioprine in maintenance lung transplant recipients: an international, randomized, double-blind clinical trial. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20060101 |
| Evaluation of the cost effectiveness of sirolimus versus tacrolimus for immunosuppression following renal transplantation in the UK. | PharmacoEconomics 20060101 |
| NMR assignment of the mTOR domain responsible for rapamycin binding. | Journal of biomolecular NMR 20060101 |
| Pulsed immunosuppression with everolimus and anti-alphabeta T-cell receptor: laryngeal allograft preservation at six months. | The Annals of otology, rhinology, and laryngology 20060101 |
| [In-hospital and remote results of the use of sirolimus coated coronary stent CYPHER]. | Kardiologiia 20060101 |
| Successful reversal of acute vascular rejection and cyclosporine-associated nephrotoxicity in renal allograft with combined sirolimus and mycophenolate mofetil as immunotherapy. | Transplantation proceedings 20060101 |
| Individualization of immunosuppressive therapy. II. Sirolimus as a less nephrotoxic alternative to calcineurin inhibitors. | Transplantation proceedings 20060101 |
| Economic evaluation of sirolimus-based immunosuppressive regimens in kidney graft recipients. | Transplantation proceedings 20060101 |
| High-performance liquid chromatography versus immunoassay for the measurement of sirolimus: comparison of two methods. | Transplantation proceedings 20060101 |
| Conversion to sirolimus from cyclosporine may induce nephrotic proteinuria and progressive deterioration of renal function in chronic allograft nephropathy patients. | Transplantation proceedings 20060101 |
| Hypoxia-inducible factor 1alpha (HIF-1alpha) correlated with tumor growth and apoptosis in ovarian cancer. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101 |
| Thrombosis after implantation of drug-eluting stents. | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101 |
| Efficacy of polyphenon E, red ginseng, and rapamycin on benzo(a)pyrene-induced lung tumorigenesis in A/J mice. | Neoplasia (New York, N.Y.) 20060101 |
| Early steroid withdrawal after renal transplantation. | Nephrology nursing journal : journal of the American Nephrology Nurses' Association 20060101 |
| [Rapamycine and mTOR inhibitors: from bench to bedside]. | Annales de biologie clinique 20060101 |
| mTOR inhibitors. | Clinical advances in hematology & oncology : H&O 20060101 |
| Mutual information-based feature selection in studying perturbation of dendritic structure caused by TSC2 inactivation. | Neuroinformatics 20060101 |
| Everolimus: a review of its use in renal and cardiac transplantation. | Drugs 20060101 |
| The engineering of endovascular stent technology: a review. | Vascular and endovascular surgery 20060101 |
| [Stent therapy with diabetic patients who have coronary artery disease]. | Clinical research in cardiology : official journal of the German Cardiac Society 20060101 |
| Evaluation of an immunoassay of whole blood sirolimus in pediatric transplant patients in comparison with high-performance liquid chromatography/tandem mass spectrometry. | Clinical chemistry and laboratory medicine 20060101 |
| The paclitaxel-eluting stent in percutaneous coronary intervention: Part II. Comparison with the sirolimus-eluting stent, economics, and unanswered questions. | Cardiology in review 20060101 |
| [Sustained rapamycin drug delivery system in prevention of high risk corneal allograft rejection and neovascularization in rabbits]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20060101 |
| The drug-eluting stent dilemma: comparing the effectiveness of Cypher versus Taxus. | Journal of cardiovascular medicine (Hagerstown, Md.) 20060101 |
| Sirolimus: friend or foe? | Respiration; international review of thoracic diseases 20060101 |
| Rheb activation of mTOR and S6K1 signaling. | Methods in enzymology 20060101 |
| The paradox of sirolimus-induced immunosuppression and tumor control. | Dermatology (Basel, Switzerland) 20060101 |
| Posttransplant Kaposi's sarcoma restricted to the site of a previous deep venous thrombosis: abrupt onset after withdrawal of sirolimus. | Dermatology (Basel, Switzerland) 20060101 |
| Cost effectiveness of the sirolimus-eluting stent in high-risk patients in Canada: an analysis from the C-SIRIUS trial. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101 |
| Renal function in renal or liver transplant recipients after conversion from a calcineurin inhibitor to sirolimus. | Clinical transplantation 20060101 |
| Role of FK778 alone or in combination with tacrolimus or mTOR inhibitors as an immunomodulator of immunofunctions: in vitro evaluation of T cell proliferation and the expression of lymphocyte surface antigens. | International journal of immunopathology and pharmacology 20060101 |
| Cluster analysis of protein array results via similarity of Gene Ontology annotation. | BMC bioinformatics 20060101 |
| Cost-effectiveness of sirolimus therapy with early cyclosporin withdrawal vs. long-term cyclosporin therapy in Australia. | Clinical transplantation 20060101 |
| The mTOR inhibitor rapamycin down-regulates the expression of the ubiquitin ligase subunit Skp2 in breast cancer cells. | Breast cancer research : BCR 20060101 |
| Role of cytomegalovirus and Epstein-Barr virus in patients with de novo colon cancer after renal transplantation. | Tumori 20060101 |
| Protective roles for induction of autophagy in multiple proteinopathies. | Autophagy 20060101 |
| Lysosomal turnover of GABARAP-phospholipid conjugate is activated during differentiation of C2C12 cells to myotubes without inactivation of the mTor kinase-signaling pathway. | Autophagy 20060101 |
| Deletion of HOG1 leads to Osmosensitivity in starvation-induced, but not rapamycin-dependent Atg8 degradation and proteolysis: further evidence for different regulatory mechanisms in yeast autophagy. | Autophagy 20060101 |
| Late acute thrombosis after implantation of sirolimus-eluting stent to treat in-stent restenosis. | Acute cardiac care 20060101 |
| [Sirolimus-induced onychopathy in renal transplant recipients]. | Annales de dermatologie et de venereologie 20060101 |
| [Study of drugs against neoplastic metastasis]. | Magyar onkologia 20060101 |
| The mTOR pathway in breast cancer. | Journal of mammary gland biology and neoplasia 20060101 |
| Conversion to sirolimus in pediatric renal transplantation recipients. | Transplantation proceedings 20060101 |
| Validation of using gene expression in mononuclear cells as a marker for hepatic cholesterol metabolism. | Lipids in health and disease 20060101 |
| Effect of cyclosporine and sirolimus on the expression of connective tissue growth factor in rat experimental chronic nephrotoxicity. | American journal of nephrology 20060101 |
| Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels. | BMC cell biology 20060101 |
| Is sirolimus better than paclitaxel? A review of the comparative data on drug-eluting stents. | Cardiovascular revascularization medicine : including molecular interventions 20060101 |
| Optimal dosing and duration of oral everolimus to inhibit in-stent neointimal growth in rabbit iliac arteries. | Cardiovascular revascularization medicine : including molecular interventions 20060101 |
| Morphoproteomic and pharmacoproteomic rationale for mTOR effectors as therapeutic targets in head and neck squamous cell carcinoma. | Annals of clinical and laboratory science 20060101 |
| Morphoproteomic and molecular concomitants of an overexpressed and activated mTOR pathway in renal cell carcinomas. | Annals of clinical and laboratory science 20060101 |
| Evaluation of a microparticle enzyme immunoassay for the measurement of sirolimus in whole blood (Abbott IMx sirolimus). | Clinical laboratory 20060101 |
| Oral immunosuppressive drugs. | Clinical medicine (London, England) 20060101 |
| Excellent clinical outcomes in primary kidney transplant recipients treated with steroid-free maintenance immunosuppression. | Clinical transplantation 20060101 |
| [Comparison of high-resolution liquid chromatography versus microparticle enzyme immunoassay for the measurement of sirolimus levels in renal transplantation]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101 |
| Cardiac overexpression of metallothionein rescues chronic alcohol intake-induced cardiomyocyte dysfunction: role of Akt, mammalian target of rapamycin and ribosomal p70s6 kinase. | Alcohol and alcoholism (Oxford, Oxfordshire) 20060101 |
| Sirolimus population pharmacokinetic/pharmacogenetic analysis and bayesian modelling in kidney transplant recipients. | Clinical pharmacokinetics 20060101 |
| Method development and validation for zotarolimus concentration determination in stented swine arteries by liquid chromatography/tandem mass spectrometry detection. | Rapid communications in mass spectrometry : RCM 20060101 |
| Successive, rapid recurrences of in-stent restenoses in a woman with angina pectoris. | Internal medicine (Tokyo, Japan) 20060101 |
| Drug-eluting stents. | Archivos de cardiologia de Mexico 20060101 |
| The role and value of sirolimus administration in kidney and liver transplantation. | Clinical transplantation 20060101 |
| Sirolimus-induced interstitial pneumonitis. | Journal of postgraduate medicine 20060101 |
| Switching from HPLC/UV to MEIA for whole blood sirolimus quantitation: comparison of methods. | Journal of clinical laboratory analysis 20060101 |
| Regulating cell surface glycosylation with a small-molecule switch. | Methods in enzymology 20060101 |
| Subacute thrombosis following implantation of zotarolimus-eluting stent. | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101 |
| Sirolimus-associated proteinuria and renal dysfunction. | Drug safety 20060101 |
| [Efficacy of the use of sirolimus covered stents in the treatment of diffuse atherosclerotic lesions of coronary arteries]. | Kardiologiia 20060101 |
| Targeting mTOR for cancer treatment. | Advances in experimental medicine and biology 20060101 |
| Promoting vascular regeneration as an alternative to conventional angioplasty-based intervention. | Endothelium : journal of endothelial cell research 20060101 |
| Comparison of paclitaxel-eluting stent and sirolimus-eluting stent expansion at incremental delivery pressures. | Cardiovascular revascularization medicine : including molecular interventions 20060101 |
| Resolution of neurotoxicity and beta-cell toxicity in an islet transplant recipient following substitution of tacrolimus with MMF. | Cell transplantation 20060101 |
| Thrombosis of drug-eluting stents: fact or fiction? | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20060101 |
| Clinical benefits of drug-eluting stents: results from RAVEL and beyond. | The Journal of cardiovascular nursing 20060101 |
| [Lung toxicity induced by rapamycin]. | Revista portuguesa de pneumologia 20060101 |
| Mammalian target of rapamycin is a promising target for novel therapeutic strategy against cancer. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20060101 |
| [Use of 'Cypher' sirolimus-eluting stents in coronary heart disease patients with different types of coronary arterial lesions]. | Vestnik rentgenologii i radiologii 20060101 |
| Contribution of transplantation to the development of medical science. How transplantation contributes to the world of medicine. | Annals of transplantation 20060101 |
| Sirolimus-eluting stents. (The results of the five-year use for the treatment of coronary artery disease). | Angiologiia i sosudistaia khirurgiia = Angiology and vascular surgery 20060101 |
| A prospective, open-label trial of sirolimus in the treatment of focal segmental glomerulosclerosis. | Clinical journal of the American Society of Nephrology : CJASN 20060101 |
| Preface. Sirolimus and kidney transplantation. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101 |
| Current trends in immunosuppression. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101 |
| Transplantation and tumors. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101 |
| Sirolimus, the first mTOR inhibitor. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101 |
| Sirolimus use in de 'novo renal' transplantation. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101 |
| Conversion to sirolimus. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101 |
| Handling sirolimus in clinical practice. Spanish Nephrology Society. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20060101 |
| [Long-term clinical efficiency of endovascular treatment using Cypher rapamycin-eluting stents in patients with coronary heart disease]. | Vestnik rentgenologii i radiologii 20060101 |
| Anesthetic rejection followed by surgical salvage. | Clinical transplants 20060101 |
| Cyclosporine A, FK-506, 40-0-[2-hydroxyethyl]rapamycin and mycophenolate mofetil inhibit proliferation of human intrahepatic biliary epithelial cells in vitro. | World journal of gastroenterology 20051228 |
| Apolipoprotein E genotypes as predictors of high-risk groups for developing hyperlipidemia in kidney transplant recipients undergoing sirolimus treatment. | Transplantation 20051227 |
| Sirolimus use and de novo minimal change nephropathy following renal transplantation. | Transplantation 20051227 |
| mTOR regulates cell survival after etoposide treatment in primary AML cells. | Blood 20051215 |
| Attenuation of cardiac hypertrophy by inhibiting both mTOR and NFkappaB activation in vivo. | Free radical biology & medicine 20051215 |
| Comparison between sirolimus-eluting stents and intracoronary catheter-based beta radiation for the treatment of in-stent restenosis. | The American journal of cardiology 20051215 |
| Clinical outcome following aleatory implantation of paclitaxel-eluting or sirolimus-eluting stents in complex coronary lesions. | The American journal of cardiology 20051215 |
| Low-dose radiation plus rapamycin promotes long-term bone marrow chimerism. | Transplantation 20051215 |
| Conversion from cyclosporine to sirolimus in stable renal transplant recipients. | Transplantation 20051215 |
| Control of dendritic arborization by the phosphoinositide-3'-kinase-Akt-mammalian target of rapamycin pathway. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20051207 |
| Local and systemic drug competition in drug-eluting stent tissue deposition properties. | Journal of controlled release : official journal of the Controlled Release Society 20051205 |
| Superiority of sirolimus eluting stent compared with intracoronary beta radiation for treatment of in-stent restenosis: a matched comparison. | Heart (British Cardiac Society) 20051201 |
| Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells. | Journal of cellular physiology 20051201 |
| mTOR function in skeletal muscle hypertrophy: increased ribosomal RNA via cell cycle regulators. | American journal of physiology. Cell physiology 20051201 |
| Enhancement of translation elongation in neurons by brain-derived neurotrophic factor: implications for mammalian target of rapamycin signaling. | Journal of neurochemistry 20051201 |
| Rapamycin analogs with reduced systemic exposure. | Bioorganic & medicinal chemistry letters 20051201 |
| Synergistic effect of targeting mTOR by rapamycin and depleting ATP by inhibition of glycolysis in lymphoma and leukemia cells. | Leukemia 20051201 |
| Noninvasive imaging of protein-protein interactions from live cells and living subjects using bioluminescence resonance energy transfer. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051201 |
| S6 kinase 2 potentiates interleukin-3-driven cell proliferation. | Journal of leukocyte biology 20051201 |
| Rapamycin for treatment of chronic allograft nephropathy in renal transplant patients. | Journal of the American Society of Nephrology : JASN 20051201 |
| Vascular response to sirolimus-eluting stents delivered with a nonaggressive implantation technique: comparison of intravascular ultrasound results from the multicenter, randomized E-SIRIUS, and SIRIUS trials. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051201 |
| In smooth muscle, FK506-binding protein modulates IP3 receptor-evoked Ca2+ release by mTOR and calcineurin. | Journal of cell science 20051201 |
| Drug-eluting stents for the treatment of intracranial atherosclerosis: initial experience and midterm angiographic follow-up. | Stroke 20051201 |
| Pilot study with an intensified oral sirolimus regimen for the prevention of in-stent restenosis in de novo lesions: a serial intravascular ultrasound study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051201 |
| Pharmacokinetics of sirolimus (rapamycin) in subjects with mild to moderate hepatic impairment. | Journal of clinical pharmacology 20051201 |
| Inhibition of target of rapamycin signaling by rapamycin in the unicellular green alga Chlamydomonas reinhardtii. | Plant physiology 20051201 |
| Mechanisms of everolimus-induced glomerulosclerosis after glomerular injury in the rat. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201 |
| Influence of co-medication with sirolimus or cyclosporine on mycophenolic acid pharmacokinetics in kidney transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201 |
| Alemtuzumab induction and sirolimus plus mycophenolate mofetil maintenance for CNI and steroid-free kidney transplant immunosuppression. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201 |
| Calcineurin inhibitor withdrawal from sirolimus-based therapy in kidney transplantation: a systematic review of randomized trials. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051201 |
| Development and validation of a high-throughput assay for quantification of the proliferation inhibitor ABT-578 using LC/LC-MS/MS in blood and tissue samples. | Therapeutic drug monitoring 20051201 |
| Technology Insight: an overview of research in drug-eluting stents. | Nature clinical practice. Cardiovascular medicine 20051201 |
| Thrombotic microangiopathy in marginal kidneys after sirolimus use. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20051201 |
| Biochemical monitoring of mTOR inhibitor-based immunosuppression following kidney transplantation: a novel approach for tailored immunosuppressive therapy. | Kidney international 20051201 |
| Rapamycin worsens renal function and intratubular cast formation in protein overload nephropathy. | Kidney international 20051201 |
| Sirolimus-induced interstitial pneumonitis in a renal transplant patient. | Respiratory care 20051201 |
| Drug-eluting coronary stents. | The New England journal of medicine 20051201 |
| Time course of release of inflammatory markers after coronary stenting: comparison between bare metal stent and sirolimus-eluting stent. | Coronary artery disease 20051201 |
| Drug-eluting coronary stents. | The New England journal of medicine 20051201 |
| Drug-eluting coronary stents. | The New England journal of medicine 20051201 |
| Drug-eluting coronary stents. | The New England journal of medicine 20051201 |
| Drug-eluting coronary stents. | The New England journal of medicine 20051201 |
| Rapamycin-sensitive pathway regulates mitochondrial membrane potential, autophagy, and survival in irradiated MCF-7 cells. | Cancer research 20051201 |
| Cypher versus taxus: are there differences? | Journal of interventional cardiology 20051201 |
| Treatment of unprotected left main coronary artery stenosis in the drug-eluting stent era. | Journal of interventional cardiology 20051201 |
| Should degenerated saphenous vein grafts routinely be sealed with drug-eluting stents? | Journal of interventional cardiology 20051201 |
| Immunosuppressive treatment and progression of histologic lesions in kidney allografts. | Kidney international. Supplement 20051201 |
| The hypoxic microenvironment of the skin contributes to Akt-mediated melanocyte transformation. | Cancer cell 20051201 |
| Outcome of percutaneous hybrid coronary revascularization: bare metal stents jeopardize the benefit of sirolimus-eluting stents in the real world. | The Canadian journal of cardiology 20051201 |
| Sirolimus: its role in nephrology. | Nephrology (Carlton, Vic.) 20051201 |
| Sirolimus-eluting versus bare stents for bailout after suboptimal infrapopliteal angioplasty for critical limb ischemia: 6-month angiographic results from a nonrandomized prospective single-center study. | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20051201 |
| Sirolimus in cardiac transplantation: use as a primary immunosuppressant in calcineurin inhibitor-induced nephrotoxicity. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051201 |
| Bone morphogenetic protein-2-induced transformation involves the activation of mammalian target of rapamycin. | Molecular cancer research : MCR 20051201 |
| Everolimus (certican) in heart transplantation: optimizing renal function through minimizing cyclosporine exposure. | Transplantation proceedings 20051201 |
| Sirolimus conversion after liver transplantation: improvement in measured glomerular filtration rate after 2 years. | Transplantation proceedings 20051201 |
| Late acute cardiac allograft rejection: new therapeutic options? | Transplantation proceedings 20051201 |
| Late expression of nitroreductase in an oncolytic adenovirus sensitizes colon cancer cells to the prodrug CB1954. | Human gene therapy 20051201 |
| Biomarkers for toxicodynamic monitoring of immunosuppressants: NMR-based quantitative metabonomics of the blood. | Therapeutic drug monitoring 20051201 |
| Complete regression of visceral Kaposi's sarcoma after conversion to sirolimus. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20051201 |
| [The safety and efficacy of Cypher drug-eluting stent: results from a six months follow-up study in patients with ST-segment elevation myocardial infarction]. | Zhonghua xin xue guan bing za zhi 20051201 |
| Drug-eluting stent: a review and update. | Vascular health and risk management 20051201 |
| Glutamatergic regulation of the p70S6 kinase in primary mouse neurons. | The Journal of biological chemistry 20051118 |
| mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. | Cell 20051118 |
| Comparison of effects of drug-eluting stents versus bare metal stents on plasma C-reactive protein levels. | The American journal of cardiology 20051115 |
| Impact of diabetes mellitus on angiographic and clinical outcomes in the drug-eluting stents era. | The American journal of cardiology 20051115 |
| Effect of sirolimus-eluting stent in diabetic patients with small coronary arteries (a SES-SMART substudy). | The American journal of cardiology 20051115 |
| Impact of asymmetric stent expansion on neointimal hyperplasia following sirolimus-eluting stent implantation. | The American journal of cardiology 20051115 |
| Proteinuria following a switch from calcineurin inhibitors to sirolimus. | Transplantation 20051115 |
| Superior outcomes in renal transplantation after early cyclosporine withdrawal and sirolimus maintenance therapy, regardless of baseline renal function. | Transplantation 20051115 |
| Anemia after late introduction of sirolimus may correlate with biochemical evidence of a chronic inflammatory state. | Transplantation 20051115 |
| Sirolimus monotherapy: feasible immunosuppression for long-term follow-up of kidney transplantation--a pilot experience. | Transplantation 20051115 |
| Post-transplantation proteinuria and sirolimus. | The New England journal of medicine 20051110 |
| Drug-eluting stents: sirolimus and paclitaxel differentially affect cultured cells and injured arteries. | European journal of pharmacology 20051107 |
| A systematic review and economic analysis of drug-eluting coronary stents available in Australia. | The Medical journal of Australia 20051107 |
| PTEN-induction in U251 glioma cells decreases the expression of insulin-like growth factor binding protein-2. | Biochemical and biophysical research communications 20051104 |
| A novel drug-eluting stent spray-coated with multi-layers of collagen and sirolimus. | Journal of controlled release : official journal of the Controlled Release Society 20051102 |
| Role of oral rapamycin to prevent restenosis in patients with de novo lesions undergoing coronary stenting: results of the Argentina single centre study (ORAR trial). | Heart (British Cardiac Society) 20051101 |
| Reduced cardiac hypertrophy in toll-like receptor 4-deficient mice following pressure overload. | Cardiovascular research 20051101 |
| Long-term results in renal transplant patients with allograft dysfunction after switching from calcineurin inhibitors to sirolimus. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20051101 |
| LDL-cholesterol predicts negative coronary artery remodelling in diabetic patients: an intravascular ultrasound study. | European heart journal 20051101 |
| Protein turnover in cardiac cell growth and survival. | Cardiovascular research 20051101 |
| Ca2+-dependent reduction of IK1 in rat ventricular cells: a novel paradigm for arrhythmia in heart failure? | Cardiovascular research 20051101 |
| Protective effect of calcineurin inhibitors on acoustic injury of the cochlea. | Hearing research 20051101 |
| Sirolimus-induced ulceration of the small bowel in islet transplant recipients: report of two cases. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051101 |
| Impairment of renal function after islet transplant alone or islet-after-kidney transplantation using a sirolimus/tacrolimus-based immunosuppressive regimen. | Transplant international : official journal of the European Society for Organ Transplantation 20051101 |
| Sirolimus-associated hepatotoxicity in the kidney graft recipient. | Transplant international : official journal of the European Society for Organ Transplantation 20051101 |
| Inflammation and caspase activation in long-term renal ischemia/reperfusion injury and immunosuppression in rats. | Kidney international 20051101 |
| Relationships between sirolimus dosing, concentration and outcomes in renal transplant recipients. | British journal of clinical pharmacology 20051101 |
| Trimethoprim-sulphamethoxazole does not affect the pharmacokinetics of sirolimus in renal transplant recipients. | British journal of clinical pharmacology 20051101 |
| Ex vivo rapamycin generates donor Th2 cells that potently inhibit graft-versus-host disease and graft-versus-tumor effects via an IL-4-dependent mechanism. | Journal of immunology (Baltimore, Md. : 1950) 20051101 |
| Ng-MIP, a surface-exposed lipoprotein of Neisseria gonorrhoeae, has a peptidyl-prolyl cis/trans isomerase (PPIase) activity and is involved in persistence in macrophages. | Molecular microbiology 20051101 |
| Paclitaxel-eluting stents in coronary artery disease. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20051101 |
| Inflammatory reaction after sirolimus-eluting stent implant. | The Annals of thoracic surgery 20051101 |
| Impact of intravascular ultrasound lesion characteristics on neointimal hyperplasia following sirolimus-eluting stent implantation. | The American journal of cardiology 20051101 |
| Predictors of edge stenosis following sirolimus-eluting stent deployment (a quantitative intravascular ultrasound analysis from the SIRIUS trial). | The American journal of cardiology 20051101 |
| Elevated glucose activates protein synthesis in cultured cardiac myocytes. | Metabolism: clinical and experimental 20051101 |
| Darbepoetin alfa treatment for post-renal transplantation anemia during pregnancy. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20051101 |
| Evaluation of four-year coronary artery response after sirolimus-eluting stent implantation using serial quantitative intravascular ultrasound and computer-assisted grayscale value analysis for plaque composition in event-free patients. | Journal of the American College of Cardiology 20051101 |
| Treatment of in-stent restenosis with sirolimus-eluting-stents -- a six month clinical and angiographic follow-up. | Zeitschrift fur Kardiologie 20051101 |
| Sirolimus-eluting stent treatment for complex proximal left anterior descending artery stenoses: 7-month clinical and angiographic results. | The Journal of invasive cardiology 20051101 |
| Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck. | Cancer research 20051101 |
| Rapamycin-coated expanded polytetrafluoroethylene bypass grafts exhibit decreased anastomotic neointimal hyperplasia in a porcine model. | Journal of vascular surgery 20051101 |
| Improvement of renal dysfunction by conversion from calcineurin inhibitors to sirolimus after heart transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051101 |
| Mammalian target of rapamycin as a therapeutic target in leukemia. | Current molecular medicine 20051101 |
| Mammalian target of rapamycin promotes vincristine resistance through multiple mechanisms independent of maintained glycolytic rate. | Molecular cancer research : MCR 20051101 |
| [Six-month intravascular ultrasound follow-up of coronary bifurcation lesions treated with rapamycin-eluting stents: technical considerations]. | Revista espanola de cardiologia 20051101 |
| [Coronary artery aneurysm one year and five months after sirolimus-eluting stent placement]. | Arquivos brasileiros de cardiologia 20051101 |
| [Sirolimus-eluting vs paclitaxel-eluting stents -- the trials confirm differences in clinical outcome]. | Kardiologia polska 20051101 |
| Evaluation of the cost-effectiveness of sirolimus versus cyclosporin for immunosuppression after renal transplantation in the United Kingdom. | Clinical therapeutics 20051101 |
| Individualization of immunosuppressive therapy: I. Sirolimus improves outcomes in African-American renal transplant recipients. | Transplantation proceedings 20051101 |
| Rapamycin at six years can exhibit normal renal function without proteinuria or neoplasia after renal transplantation. A single-center experience. | Transplantation proceedings 20051101 |
| Evolution of proteinuria after conversion from calcineurin inhibitors (CNI) to sirolimus (SRL) in renal transplant patients: a multicenter study. | Transplantation proceedings 20051101 |
| Efficacy of conversion to sirolimus in posttransplantation Kaposi's sarcoma. | Transplantation proceedings 20051101 |
| Rapamycin in lung transplantation. | Transplantation proceedings 20051101 |
| Sirolimus as an alternative to anticalcineurin therapy in heart transplantation: experience of a single center. | Transplantation proceedings 20051101 |
| [Drug eluting stents in 2005: have the initial expectations been met?]. | Annales de cardiologie et d'angeiologie 20051101 |
| [Comparison of the effects of rapamycin-eluting stent implantation and coronary artery bypass grafting in treatment of patients with multi-vessel coronary disease]. | Zhonghua yi xue za zhi 20051026 |
| RACK1 mRNA translation is regulated via a rapamycin-sensitive pathway and coordinated with ribosomal protein synthesis. | FEBS letters 20051024 |
| Protein synthesis-independent plasticity mediates rapid and precise recovery of deprived eye responses. | Neuron 20051020 |
| Impact of treatment of coronary artery disease with sirolimus-eluting stents on outcomes of diabetic and nondiabetic patients. | The American journal of cardiology 20051015 |
| Predictors of outcome after sirolimus-eluting stent implantation for complex in-stent restenosis. | The American journal of cardiology 20051015 |
| Maintenance immunosuppression with target-of-rapamycin inhibitors is associated with a reduced incidence of de novo malignancies. | Transplantation 20051015 |
| New-onset diabetes after kidney transplantation: an application of 2003 International Guidelines. | Transplantation 20051015 |
| Sirolimus and tacrolimus trough concentrations and dose requirements after kidney transplantation in relation to CYP3A5 and MDR1 polymorphisms and steroids. | Transplantation 20051015 |
| Review of major clinical trials with mycophenolate mofetil in renal transplantation. | Transplantation 20051015 |
| The impact of mycophenolate mofetil on long-term outcomes in kidney transplantation. | Transplantation 20051015 |
| Malignancy after transplantation. | Transplantation 20051015 |
| Attenuation of insulin-stimulated insulin receptor substrate-1 serine 307 phosphorylation in insulin resistance of type 2 diabetes. | The Journal of biological chemistry 20051014 |
| Synergistic inhibition of human neuroblastoma-related angiogenesis by vinblastine and rapamycin. | Oncogene 20051013 |
| [Everolimus]. | Deutsche medizinische Wochenschrift (1946) 20051007 |
| Tirofiban plus sirolimus-eluting stent vs abciximab plus bare-metal stent. | JAMA 20051005 |
| Tirofiban plus sirolimus-eluting stent vs abciximab plus bare-metal stent. | JAMA 20051005 |
| Randomized comparison of sirolimus-eluting stent versus standard stent for percutaneous coronary revascularization in diabetic patients: the diabetes and sirolimus-eluting stent (DIABETES) trial. | Circulation 20051004 |
| Differential regulation of the p70 S6 kinase pathway by interferon alpha (IFNalpha) and imatinib mesylate (STI571) in chronic myelogenous leukemia cells. | Blood 20051001 |
| Cell size reduction induced by inhibition of the mTOR/S6K-signaling pathway protects Jurkat cells from apoptosis. | Cell death and differentiation 20051001 |
| Altered centrosomes in ataxia-telangiectasia cells and rapamycin-treated Chinese hamster cells. | Environmental and molecular mutagenesis 20051001 |
| Insulin-like growth factor-I inhibits dexamethasone-induced proteolysis in cultured L6 myotubes through PI3K/Akt/GSK-3beta and PI3K/Akt/mTOR-dependent mechanisms. | The international journal of biochemistry & cell biology 20051001 |
| Combination of imatinib with rapamycin or RAD001 acts synergistically only in Bcr-Abl-positive cells with moderate resistance to imatinib. | Leukemia 20051001 |
| Rapamycin: an anti-cancer immunosuppressant? | Critical reviews in oncology/hematology 20051001 |
| T-cadherin protects endothelial cells from oxidative stress-induced apoptosis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051001 |
| Glucose metabolism in renal transplant recipients: effect of calcineurin inhibitor withdrawal and conversion to sirolimus. | Journal of the American Society of Nephrology : JASN 20051001 |
| [Late thrombosis of a drug-eluting coronary stent after antiplatelet therapy discontinuation]. | Annales francaises d'anesthesie et de reanimation 20051001 |
| Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development. | Leukemia 20051001 |
| Concentration-controlled use of sirolimus associated with reduced exposure of cyclosporine in black recipients of primarily living renal allograft donors: 12-month results. | Clinical transplantation 20051001 |
| Sirolimus-associated interstitial pneumonitis in solid organ transplant recipients. | Clinical transplantation 20051001 |
| The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosis. | Apoptosis : an international journal on programmed cell death 20051001 |
| ISR II study: a long-term evaluation of sirolimus-eluting stent in the treatment of patients with in-stent restenotic native coronary artery lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051001 |
| Sirolimus-eluting stents: safe and effective in the treatment of in-stent restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20051001 |
| Comparison of pharmacokinetics of the sirolimus-eluting stent in Japanese patients with those in American patients. | Journal of cardiovascular pharmacology 20051001 |
| Rapamycin attenuates atherosclerotic plaque progression in apolipoprotein E knockout mice: inhibitory effect on monocyte chemotaxis. | Journal of cardiovascular pharmacology 20051001 |
| Involvement of c-Jun NH2 terminal kinase and p38MAPK in rapamycin-mediated inhibition of neointimal formation in rat carotid arteries. | Journal of cardiovascular pharmacology 20051001 |
| Sirolimus-induced thrombotic microangiopathy is associated with decreased expression of vascular endothelial growth factor in kidneys. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001 |
| A randomized controlled trial of late conversion from CNI-based to sirolimus-based immunosuppression following renal transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001 |
| Three-year efficacy and safety results from a study of everolimus versus mycophenolate mofetil in de novo renal transplant patients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001 |
| Comparison of sirolimus with low-dose tacrolimus versus sirolimus-based calcineurin inhibitor-free regimen in live donor renal transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20051001 |
| Hypoxia inducible factor-1: a novel target for cancer therapy. | Anti-cancer drugs 20051001 |
| Expression of proline-rich Akt-substrate PRAS40 in cell survival pathway and carcinogenesis. | Acta pharmacologica Sinica 20051001 |
| The role of therapeutic monitoring of everolimus in solid organ transplantation. | Therapeutic drug monitoring 20051001 |
| New drug-eluting stents, optimizing technique, and the problem of drug-eluting stent restenosis. | Minerva cardioangiologica 20051001 |
| Pharmacokinetic interaction between verapamil and everolimus in healthy subjects. | British journal of clinical pharmacology 20051001 |
| Thrombosis of sirolimus-eluting coronary stent in the postanesthesia care unit. | Anesthesia and analgesia 20051001 |
| Angiographic and clinical outcomes of a pharmacokinetic study of sirolimus-eluting stents: lesson from restenosis cases. | Circulation journal : official journal of the Japanese Circulation Society 20051001 |
| Sirolimus-eluting stent implantation in diabetic patients with multivessel coronary artery disease. | American heart journal 20051001 |
| Pirfenidone inhibits obliterative airway disease in mouse tracheal allografts. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20051001 |
| The Candida albicans vacuole is required for differentiation and efficient macrophage killing. | Eukaryotic cell 20051001 |
| Inhibition of the mammalian target of rapamycin and the induction of cell cycle arrest in mantle cell lymphoma cells. | Haematologica 20051001 |
| Mammalian target of rapamycin inhibitors activate the AKT kinase in multiple myeloma cells by up-regulating the insulin-like growth factor receptor/insulin receptor substrate-1/phosphatidylinositol 3-kinase cascade. | Molecular cancer therapeutics 20051001 |
| Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells. | Neoplasia (New York, N.Y.) 20051001 |
| [Experimental study on the effects of rapamycin in prevention of rat corneal allograft rejection]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20051001 |
| Potential role of mammalian target of rapamycin inhibitors in breast cancer therapy. | Clinical breast cancer 20051001 |
| [Primary study of vasculogenic mimicry induced by hypoxia in epithelial ovarian carcinoma]. | Zhonghua fu chan ke za zhi 20051001 |
| [Drug-eluting stents: indications, limits and future development]. | Archives des maladies du coeur et des vaisseaux 20051001 |
| Sirolimus inhibits platelet-derived growth factor-induced collagen synthesis in rat vascular smooth muscle cells. | Transplantation proceedings 20051001 |
| A pilot study of immunosuppression minimization after pancreas-kidney transplantation utilizing thymoglobulin induction and sirolimus maintenance therapy. | Transplantation proceedings 20051001 |
| Experience with sirolimus for calcineurin minimization/elimination in pancreas-after-kidney transplantation. | Transplantation proceedings 20051001 |
| Metabolic effect of sirolimus versus mycophenolate mofetil on pancreatic graft function in the early posttransplant period. | Transplantation proceedings 20051001 |
| Diabetes and percutaneous coronary intervention in the setting of an acute coronary syndrome. | Diabetes & vascular disease research 20051001 |
| [Sirolimus for rescue of recurrent acute rejection and diabetes mellitus after liver transplantation: report of one case]. | Revista medica de Chile 20051001 |
| Sirolimus: a new immunosuppressant. | The Journal of the Association of Physicians of India 20051001 |
| [Advances on PI3K/Akt/mTOR signalling pathway in malignancies]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20051001 |
| Rapamycin, but not FK-506, increases endothelial tissue factor expression: implications for drug-eluting stent design. | Circulation 20050927 |
| Low incidence of malignancy among sirolimus/cyclosporine-treated renal transplant recipients. | Transplantation 20050927 |
| Comparison of steroid avoidance in tacrolimus/mycophenolate mofetil and tacrolimus/sirolimus combination in kidney transplantation monitored by surveillance biopsy. | Transplantation 20050927 |
| mTOR inhibition and its effect on cancer in transplantation. | Transplantation 20050927 |
| Lithium induces autophagy by inhibiting inositol monophosphatase. | The Journal of cell biology 20050926 |
| Shp2 is required for protein kinase C-dependent phosphorylation of serine 307 in insulin receptor substrate-1. | The Journal of biological chemistry 20050923 |
| The FK506 binding protein Fpr3 counteracts protein phosphatase 1 to maintain meiotic recombination checkpoint activity. | Cell 20050923 |
| Late incomplete stent apposition after sirolimus-eluting stent implantation: a serial intravascular ultrasound analysis. | Journal of the American College of Cardiology 20050920 |
| Overexpression of NBS1 contributes to transformation through the activation of phosphatidylinositol 3-kinase/Akt. | The Journal of biological chemistry 20050916 |
| Tolerability of cyclosphosphamide and methotrexate induction immunosuppression in nonhuman primates. | Toxicology 20050915 |
| Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism. | Bioorganic & medicinal chemistry letters 20050915 |
| Inhibition of the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway but not the MEK/ERK pathway attenuates laminin-mediated small cell lung cancer cellular survival and resistance to imatinib mesylate or chemotherapy. | Cancer research 20050915 |
| Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasis. | Genes & development 20050915 |
| Late restenosis in patients receiving a polymer-coated sirolimus-eluting stent. | Annals of internal medicine 20050906 |
| Effectiveness of sirolimus-eluting stent implantation for the treatment of ostial left anterior descending artery stenosis with intravascular ultrasound guidance. | Journal of the American College of Cardiology 20050906 |
| Local perivascular delivery of anti-restenotic agents from a drug-eluting poly(epsilon-caprolactone) stent cuff. | Biomaterials 20050901 |
| One year clinical follow up of paclitaxel eluting stents for acute myocardial infarction compared with sirolimus eluting stents. | Heart (British Cardiac Society) 20050901 |
| A rapamycin derivative (everolimus) controls proliferation through down-regulation of truncated CCAAT enhancer binding protein {beta} and NF-{kappa}B activity in Hodgkin and anaplastic large cell lymphomas. | Blood 20050901 |
| CCI-779 in metastatic melanoma: a phase II trial of the California Cancer Consortium. | Cancer 20050901 |
| Cardiovascular risk profile with the new immunosuppressive combinations after renal transplantation. | Journal of hypertension 20050901 |
| Sirolimus in combination with tacrolimus is associated with worse renal allograft survival compared to mycophenolate mofetil combined with tacrolimus. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901 |
| Proteinuria developing after clinical islet transplantation resolves with sirolimus withdrawal and increased tacrolimus dosing. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901 |
| Analysis of exposure-response relationship in everolimus-cyclosporine combination regimen. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901 |
| Therapeutic drug monitoring for everolimus in heart transplant recipients: flawed model or a model for future use? | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050901 |
| Bone metabolism in renal transplant patients treated with cyclosporine or sirolimus. | Transplant international : official journal of the European Society for Organ Transplantation 20050901 |
| Immune cells in a heterotopic lamb-to-pig bronchial xenograft model. | Transplant international : official journal of the European Society for Organ Transplantation 20050901 |
| Recurrence of in-stent restenosis in cardiac allograft vasculopathy following implantation of a sirolimus-eluting stent. | Transplant international : official journal of the European Society for Organ Transplantation 20050901 |
| lipase-catalyzed regioselective esterification of rapamycin: synthesis of temsirolimus (CCI-779). | Organic letters 20050901 |
| Simultaneous measurement of sirolimus and everolimus in whole blood by HPLC with ultraviolet detection. | Clinical chemistry 20050901 |
| Effectiveness of the concomitant use of bivalirudin and drug-eluting stents (from the prospective, multicenter BivAlirudin and Drug-Eluting STents [ADEST] study). | The American journal of cardiology 20050901 |
| Inhibition of PI-3 kinase/Akt/mTOR, but not calcineurin signaling, reverses insulin-like growth factor I-induced protection against glucose toxicity in cardiomyocyte contractile function. | The Journal of endocrinology 20050901 |
| Re-stenosis of a sirolimus-coated stent in a heart transplant recipient with allograft vasculopathy. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050901 |
| Sirolimus- and taxol-eluting stents differ towards intimal hyperplasia and re-endothelialization. | The Journal of invasive cardiology 20050901 |
| Genetic analysis of the TOR pathway in Aspergillus nidulans. | Eukaryotic cell 20050901 |
| Incremental cost-effectiveness of drug-eluting stents compared with a third-generation bare-metal stent in a real-world setting: randomised Basel Stent Kosten Effektivitäts Trial (BASKET). | Lancet (London, England) 20050901 |
| An evaluation of the Abbott IMx sirolimus assay in relation to a high-performance liquid chromatography-ultraviolet method. | Annals of clinical biochemistry 20050901 |
| Incidence and predictors of restenosis after sirolimus-eluting stent implantation in high-risk patients. | American heart journal 20050901 |
| Update on drug-eluting coronary stents. | Expert review of cardiovascular therapy 20050901 |
| How soon can a patient undergo noncardiac surgery after receiving a drug-eluting stent? | Cleveland Clinic journal of medicine 20050901 |
| [Molecular targeted therapy for malignant brain tumors]. | Nihon rinsho. Japanese journal of clinical medicine 20050901 |
| Percutaneous treatment of the left main coronary artery ostial obstruction following aortic valve replacement. | Italian heart journal : official journal of the Italian Federation of Cardiology 20050901 |
| Sirolimus as primary immunosuppression agent in kidney transplant recipients: Akdeniz University experience. | Transplantation proceedings 20050901 |
| Early acute rejection episodes in renal transplantation in relation to immunosuppression protocols: an audit of 100 cases. | Transplantation proceedings 20050901 |
| Observations on quadruple immunosuppression maintenance therapy using rapamycin, low-dose cyclosporine, mycophenolate mofetil, and prednisone following ATG induction. | Transplantation proceedings 20050901 |
| [Sirolimus-eluting stent for in-stent restenosis treatment: single center results in an unselected study population]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20050901 |
| Active stents in diabetic patients. | Diabetes & metabolism 20050901 |
| Pharmacokinetics of sirolimus in Thai healthy volunteers. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20050901 |
| Kaposi's sarcoma after renal transplantation. | The New England journal of medicine 20050825 |
| Kaposi's sarcoma after renal transplantation. | The New England journal of medicine 20050825 |
| Images in cardiovascular medicine. Giant coronary aneurysm formation after sirolimus-eluting stent implantation in Kawasaki disease. | Circulation 20050823 |
| Enhanced radiation damage of tumor vasculature by mTOR inhibitors. | Oncogene 20050818 |
| Sirolimus-eluting and paclitaxel-eluting stents for coronary revascularization. | The New England journal of medicine 20050818 |
| Paclitaxel-eluting or sirolimus-eluting stents to prevent restenosis in diabetic patients. | The New England journal of medicine 20050818 |
| Healing Achilles--sirolimus versus paclitaxel. | The New England journal of medicine 20050818 |
| Sirolimus-eluting stents vs paclitaxel-eluting stents in patients with coronary artery disease: meta-analysis of randomized trials. | JAMA 20050817 |
| [Short and long-term therapeutic effects of rapamycin-eluting stent and paclitaxel-eluting stent in treatment of coronary disease with complicated lesions]. | Zhonghua yi xue za zhi 20050817 |
| Bifurcation coronary lesions treated with the 'crush' technique: an intravascular ultrasound analysis. | Journal of the American College of Cardiology 20050816 |
| Clinical and angiographic outcome after implantation of drug-eluting stents in bifurcation lesions with the crush stent technique: importance of final kissing balloon post-dilation. | Journal of the American College of Cardiology 20050816 |
| Rapamycin stimulates apoptosis of childhood acute lymphoblastic leukemia cells. | Blood 20050815 |
| A prospective, randomized trial of tacrolimus in combination with sirolimus or mycophenolate mofetil in kidney transplantation: results at 1 year. | Transplantation 20050815 |
| Robust tolerance to fully allogeneic islet transplants achieved by chimerism with minimal conditioning. | Transplantation 20050815 |
| Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition. | Cancer research 20050815 |
| Novel fusion protein approach for efficient high-throughput screening of small molecule-mediating protein-protein interactions in cells and living animals. | Cancer research 20050815 |
| [Treatment and prevention of restenosis after percutaneous coronary intervention. Balloons, stents, radioactive rays and drug-releasing stents]. | Ugeskrift for laeger 20050815 |
| Phase II study of temsirolimus (CCI-779), a novel inhibitor of mTOR, in heavily pretreated patients with locally advanced or metastatic breast cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050810 |
| Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050810 |
| Phase II trial of temsirolimus (CCI-779) in recurrent glioblastoma multiforme: a North Central Cancer Treatment Group Study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050810 |
| 4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy. | American journal of respiratory cell and molecular biology 20050801 |
| Resolution of renal allograft-associated post-transplant lymphoproliferative disorder with the introduction of sirolimus. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050801 |
| Late thrombosis of sirolimus-eluting stents following noncardiac surgery. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801 |
| Everolimus treatment downregulates renocortical cyclooxygenase-2 expression in the rat kidney. | British journal of pharmacology 20050801 |
| Selective versus exclusive use of sirolimus-eluting stent implantation in multivessel coronary artery disease. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801 |
| Late thrombosis following treatment of in-stent restenosis with drug-eluting stents after discontinuation of antiplatelet therapy. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801 |
| Prevention of restenosis by a novel drug-eluting stent system with a dose-adjustable, polymer-free, on-site stent coating. | European heart journal 20050801 |
| Impact of sirolimus-eluting stents on outcomes of patients treated for acute myocardial infarction by primary angioplasty. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050801 |
| Pre-transplant IFN-gamma ELISPOTs are associated with post-transplant renal function in African American renal transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050801 |
| Adding sirolimus to tacrolimus-based immunosuppression in pediatric renal transplant recipients reduces tacrolimus exposure. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050801 |
| Islet transplantation in type 1 diabetes mellitus using cultured islets and steroid-free immunosuppression: Miami experience. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050801 |
| Use of drug-eluting stents for the treatment of in-stent restenosis in routine clinical practice. | Coronary artery disease 20050801 |
| An expanding role for mTOR in cancer. | Trends in molecular medicine 20050801 |
| Phase II study of CCI-779 in patients with recurrent glioblastoma multiforme. | Investigational new drugs 20050801 |
| Gas6 induces Akt/mTOR-mediated mesangial hypertrophy in diabetic nephropathy. | Kidney international 20050801 |
| Mycophenolate mofetil in islet cell transplant: variable pharmacokinetics but good correlation between total and unbound concentrations. | Journal of clinical pharmacology 20050801 |
| A phase I multiple-dose escalation study characterizing pharmacokinetics and safety of ABT-578 in healthy subjects. | Journal of clinical pharmacology 20050801 |
| Generalized, pruritic, ulcerating maculopapular rash necessitating cessation of sirolimus in a liver transplantation patient. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20050801 |
| Sirolimus-related toxicity in stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050801 |
| Sirolimus in combination with tacrolimus and corticosteroids for the treatment of resistant chronic graft-versus-host disease. | British journal of haematology 20050801 |
| Sirolimus in pediatric solid organ transplantation. | Pediatric transplantation 20050801 |
| Sirolimus in pediatric patients: results in the first 6 months post-renal transplant. | Pediatric transplantation 20050801 |
| Cardiac tamponade in a pediatric renal transplant recipient on sirolimus therapy. | Pediatric transplantation 20050801 |
| Comparison of short- (one month) and long- (twelve months) term outcomes of sirolimus- versus paclitaxel-eluting stents in 293 consecutive patients with diabetes mellitus (from the RESEARCH and T-SEARCH registries). | The American journal of cardiology 20050801 |
| RAD001 (everolimus) improves the efficacy of replicating adenoviruses that target colon cancer. | Cancer research 20050801 |
| Sirolimus-eluting stents for treatment of complex bypass graft disease: insights from the SECURE registry. | The Journal of invasive cardiology 20050801 |
| Prospective native coronary artery stenosis treated with sirolimus-eluting stent (ONASSIS) registry--acute results and mid-term outcomes: a single-center experience. | The Journal of invasive cardiology 20050801 |
| One-year clinical outcome after coronary stenting of very small vessels using 2.25 mm sirolimus- and paclitaxel-eluting stents: a comparison between the RESEARCH and T-SEARCH registries. | The Journal of invasive cardiology 20050801 |
| Balloon alignment T-stenting for bifurcation coronary artery disease using the sirolimus-eluting stent. | The Journal of invasive cardiology 20050801 |
| Sirolimus-eluting stent implantation and beta-irradiation for the treatment of in-stent restenotic lesions: comparison of underlying mechanisms of acute gain and late loss as assessed by volumetric intravascular ultrasound. | American heart journal 20050801 |
| [Drug eluting stents: from evidence based medicine to clinical practice]. | Annales de cardiologie et d'angeiologie 20050801 |
| Pim family kinases enhance tumor growth of prostate cancer cells. | Molecular cancer research : MCR 20050801 |
| Successful use of the new immune-suppressor sirolimus in IPEX (immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome). | The Journal of pediatrics 20050801 |
| A high-throughput method for screening of rapamycin-producing strains of Streptomyces hygroscopicus by cultivation in 96-well microtiter plates. | Biotechnology letters 20050801 |
| [Improved outcome with sirolimus-cyclosporine regimen in high-risk renal transplant recipients]. | Orvosi hetilap 20050731 |
| Everolimus versus mycophenolate mofetil in the prevention of rejection in de novo renal transplant recipients: a 3-year randomized, multicenter, phase III study. | Transplantation 20050727 |
| Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients. | Neurology 20050726 |
| Mutasynthesis of rapamycin analogues through the manipulation of a gene governing starter unit biosynthesis. | Angewandte Chemie (International ed. in English) 20050725 |
| Methionine sulfoximine treatment and carbon starvation elicit Snf1-independent phosphorylation of the transcription activator Gln3 in Saccharomyces cerevisiae. | The Journal of biological chemistry 20050722 |
| Antiproliferative profile of sirolimus and mycophenolate mofetil: impact of the SI/MPL ratio. | International journal of cardiology 20050720 |
| Sirolimus-eluting stents associated with paradoxic coronary vasoconstriction. | Journal of the American College of Cardiology 20050719 |
| Endothelial dysfunction after sirolimus-eluting stent placement. | Journal of the American College of Cardiology 20050719 |
| Identification of S6 kinase 1 as a novel mammalian target of rapamycin (mTOR)-phosphorylating kinase. | The Journal of biological chemistry 20050715 |
| Body weight alterations under early corticosteroid withdrawal and chronic corticosteroid therapy with modern immunosuppression. | Transplantation 20050715 |
| Differential effect of calcineurin inhibitors, anti-CD25 antibodies and rapamycin on the induction of FOXP3 in human T cells. | Transplantation 20050715 |
| Dual inhibition of mTOR and estrogen receptor signaling in vitro induces cell death in models of breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050715 |
| Regulation of the phosphorylation and integrity of protein synthesis initiation factor eIF4GI and the translational repressor 4E-BP1 by p53. | Oncogene 20050714 |
| Differential response of delayed healing and persistent inflammation at sites of overlapping sirolimus- or paclitaxel-eluting stents. | Circulation 20050712 |
| Phosphorylation of mammalian target of rapamycin (mTOR) at Ser-2448 is mediated by p70S6 kinase. | The Journal of biological chemistry 20050708 |
| Amino acid signaling through the mammalian target of rapamycin (mTOR) pathway: Role of glutamine and of cell shrinkage. | Journal of cellular physiology 20050701 |
| Drug-eluting stents compared with thin-strut bare stents for the reduction of restenosis: a prospective, randomized trial. | European heart journal 20050701 |
| Shiga toxins activate translational regulation pathways in intestinal epithelial cells. | Cellular signalling 20050701 |
| Effects of sirolimus on mesangial cell cholesterol homeostasis: a novel mechanism for its action against lipid-mediated injury in renal allografts. | American journal of physiology. Renal physiology 20050701 |
| Follicle-stimulating hormone activates p70 ribosomal protein S6 kinase by protein kinase A-mediated dephosphorylation of Thr 421/Ser 424 in primary Sertoli cells. | Molecular endocrinology (Baltimore, Md.) 20050701 |
| A novel class of dual-family immunophilins. | The Journal of biological chemistry 20050701 |
| Rapamycin ameliorates proteinuria-associated tubulointerstitial inflammation and fibrosis in experimental membranous nephropathy. | Journal of the American Society of Nephrology : JASN 20050701 |
| Modulation of insulin action by dietary proteins and amino acids: role of the mammalian target of rapamycin nutrient sensing pathway. | Current opinion in clinical nutrition and metabolic care 20050701 |
| Calcineurin inhibitor withdrawal from sirolimus-based therapy in kidney transplantation: a systematic review of randomized trials. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050701 |
| Rapamycin: a new string to the antiproteinuric bow? | Journal of the American Society of Nephrology : JASN 20050701 |
| Glycogen autophagy in the liver and heart of newborn rats. The effects of glucagon, adrenalin or rapamycin. | Histology and histopathology 20050701 |
| Phosphotidylinositol-3 kinase-mediated signals in mice immunized with the 57 kDa major antigenic outer-membrane protein of Shigella dysenteriae type 1. | Journal of medical microbiology 20050701 |
| Influence of everolimus on steady-state pharmacokinetics of cyclosporine in maintenance renal transplant patients. | Journal of clinical pharmacology 20050701 |
| Rapamycin and FK506 reduce skeletal muscle voltage sensor expression and function. | Cell calcium 20050701 |
| Roles of deletion and regulation in creating mixed chimerism and allograft tolerance using a nonlymphoablative irradiation-free protocol. | Journal of immunology (Baltimore, Md. : 1950) 20050701 |
| Stent-based delivered anti-proliferative drugs in the prevention of coronary stent restenosis. | Current medicinal chemistry. Cardiovascular and hematological agents 20050701 |
| Sirolimus and thrombotic microangiopathy after allogeneic hematopoietic stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050701 |
| The TOR and EGO protein complexes orchestrate microautophagy in yeast. | Molecular cell 20050701 |
| The efficacy of sirolimus-eluting stents versus bare metal stents for diabetic patients undergoing elective percutaneous coronary intervention. | The Journal of invasive cardiology 20050701 |
| Evolving use of drug-eluting stents in diabetic patients. | The Journal of invasive cardiology 20050701 |
| Higher exposure to mycophenolic acid with sirolimus than with cyclosporine cotreatment. | Clinical pharmacology and therapeutics 20050701 |
| [Drug-eluting stents and other anti-restenosis devices]. | Revista espanola de cardiologia 20050701 |
| Cilomilast, tacrolimus and rapamycin modulate dendritic cell function in the elicitation phase of allergic contact dermatitis. | The British journal of dermatology 20050701 |
| Control of advanced and refractory acute myelogenous leukaemia with sirolimus-based non-myeloablative allogeneic stem cell transplantation. | British journal of haematology 20050701 |
| Moving beyond the cost per quality-adjusted life year: modelling the budgetary impact and clinical outcomes associated with the use of sirolimus-eluting stents. | The Canadian journal of cardiology 20050701 |
| Modulation of tissue factor expression by rapamycin and FK-506 in lipopolysaccharide-stimulated human mononuclear cells and serum-stimulated aortic smooth muscle cells. | Thrombosis and haemostasis 20050701 |
| Angiotensin IV enhances phosphorylation of 4EBP1 by multiple signaling events in lung endothelial cells. | Molecular and cellular biochemistry 20050701 |
| Late angiographic stent thrombosis (LAST) events with drug-eluting stents. | Journal of the American College of Cardiology 20050621 |
| Synergistic growth inhibition by Iressa and Rapamycin is modulated by VHL mutations in renal cell carcinoma. | British journal of cancer 20050620 |
| Rapamycin selectively expands CD4+CD25+FoxP3+ regulatory T cells. | Blood 20050615 |
| Activation of protein synthesis in cardiomyocytes by the hypertrophic agent phenylephrine requires the activation of ERK and involves phosphorylation of tuberous sclerosis complex 2 (TSC2). | The Biochemical journal 20050615 |
| TCR engagement increases hypoxia-inducible factor-1 alpha protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells. | Journal of immunology (Baltimore, Md. : 1950) 20050615 |
| Recombinant p21 protein inhibits lymphocyte proliferation and transcription factors. | Journal of immunology (Baltimore, Md. : 1950) 20050615 |
| Comparison of effectiveness of sirolimus-eluting stents versus bare metal stents for percutaneous coronary intervention in patients at high risk for coronary restenosis or clinical adverse events. | The American journal of cardiology 20050615 |
| Risk of thrombosis with the use of sirolimus-eluting stents for percutaneous coronary intervention (from registry and clinical trial data). | The American journal of cardiology 20050615 |
| Antitumor activity of rapamycin in a transgenic mouse model of ErbB2-dependent human breast cancer. | Cancer research 20050615 |
| A crevice adjoining the ribosome tunnel: hints for cotranslational folding. | FEBS letters 20050613 |
| Epidermal growth factor and hypoxia-induced expression of CXC chemokine receptor 4 on non-small cell lung cancer cells is regulated by the phosphatidylinositol 3-kinase/PTEN/AKT/mammalian target of rapamycin signaling pathway and activation of hypoxia inducible factor-1alpha. | The Journal of biological chemistry 20050610 |
| Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells. | The Journal of biological chemistry 20050603 |
| Rapamycin induces tumor-specific thrombosis via tissue factor in the presence of VEGF. | Blood 20050601 |
| Pim and Akt oncogenes are independent regulators of hematopoietic cell growth and survival. | Blood 20050601 |
| Rapamycin inhibits fibronectin-induced migration of the human arterial smooth muscle line (E47) through the mammalian target of rapamycin. | American journal of physiology. Heart and circulatory physiology 20050601 |
| Estimation of pharmacokinetic parameters from non-compartmental variables using Microsoft Excel. | Computers in biology and medicine 20050601 |
| Long-term treatment of bile duct-ligated rats with rapamycin (sirolimus) significantly attenuates liver fibrosis: analysis of the underlying mechanisms. | The Journal of pharmacology and experimental therapeutics 20050601 |
| Identification of mTOR as a novel bifunctional target in chronic myeloid leukemia: dissection of growth-inhibitory and VEGF-suppressive effects of rapamycin in leukemic cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050601 |
| Mycotic aneurysm of left anterior descending artery after sirolimus-eluting stent implantation: a case report. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601 |
| Immediate and mid-term outcomes of sirolimus-eluting stent implantation for chronic total occlusions. | European heart journal 20050601 |
| Drug-eluting stents for chronic total occlusions make sense, but it is too early to close the discussion. | European heart journal 20050601 |
| Effect of the immunosuppressive regime of Edmonton protocol on the long-term in vitro insulin secretion from islets of two different species and age categories. | Toxicology in vitro : an international journal published in association with BIBRA 20050601 |
| The FK506-binding protein of the malaria parasite, Plasmodium falciparum, is a FK506-sensitive chaperone with FK506-independent calcineurin-inhibitory activity. | Molecular and biochemical parasitology 20050601 |
| Activation of CREB by tauroursodeoxycholic acid protects cholangiocytes from apoptosis induced by mTOR inhibition. | Hepatology (Baltimore, Md.) 20050601 |
| Early cyclosporine a withdrawal in kidney-transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions. | The Journal of urology 20050601 |
| Clinical outcomes after sirolimus-eluting stent implantation for de novo saphenous vein graft lesions. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601 |
| Rapamycin inhibits human renal epithelial cell proliferation: effect on cyclin D3 mRNA expression and stability. | Kidney international 20050601 |
| BOOP is common in cardiac transplant recipients switched from a calcineurin inhibitor to sirolimus. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601 |
| Everolimus alters the bronchoalveolar lavage and endobronchial biopsy immunologic profile post-human lung transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601 |
| A prospective randomized trial of steroid-free maintenance regimens in kidney transplant recipients--an interim analysis. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050601 |
| Very late thrombosis after implantation of sirolimus eluting stent. | Heart (British Cardiac Society) 20050601 |
| Fatal infection after rapamycin eluting coronary stent implantation. | Heart (British Cardiac Society) 20050601 |
| A paclitaxel coated stent used for in-stent restenosis within a sirolimus coated stent fails to protect against recurrent restenosis. | Heart (British Cardiac Society) 20050601 |
| Differential regulation of smooth muscle markers in human bone marrow-derived mesenchymal stem cells. | Journal of hypertension 20050601 |
| Who let the bugs in? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601 |
| Underexpansion of sirolimus-eluting stents: incidence and relationship to delivery pressure. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601 |
| Stent-based delivery of ABT-578 via a phosphorylcholine surface coating reduces neointimal formation in the porcine coronary model. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050601 |
| Incidence and predictors of target vessel revascularization and clinical event rates of the sirolimus-eluting coronary stent (results from the prospective multicenter German Cypher Stent Registry). | The American journal of cardiology 20050601 |
| CEDIA sirolimus assay compared with HPLC-MS/MS and HPLC-UV in transplant recipient specimens. | Therapeutic drug monitoring 20050601 |
| An inducible translocation strategy to rapidly activate and inhibit small GTPase signaling pathways. | Nature methods 20050601 |
| Sirolimus for solid organ transplantation in children. | Pediatric transplantation 20050601 |
| Replacing calcineurin inhibitors with mTOR inhibitors in children. | Pediatric transplantation 20050601 |
| Rapamycin inhibits human in stent restenosis vascular smooth muscle cells independently of pRB phosphorylation and p53. | Cardiovascular research 20050601 |
| Sirolimus-eluting stent for in-stent restenosis of left main coronary artery in takayasu arteritis. | Circulation journal : official journal of the Japanese Circulation Society 20050601 |
| Adverse effects of local or systemic application of rapamycin for the prevention of neointimal hyperplasia. | The Annals of thoracic surgery 20050601 |
| Drug eluting stents in 2005. | Heart (British Cardiac Society) 20050601 |
| The efficacy of sirolimus in the treatment of patients with refractory uveitis. | The British journal of ophthalmology 20050601 |
| Angiographic and clinical outcome for the treatment of in-stent restenosis with sirolimus-eluting stent compared to vascular brachytherapy. | Zeitschrift fur Kardiologie 20050601 |
| Short-term rapamycin for inhibition of neointima formation after balloon-mediated aortic injury in rats: is there a window of opportunity for systemic prophylaxis of restenosis? | Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists 20050601 |
| Farnesyltransferase inhibitors reverse altered growth and distribution of actin filaments in Tsc-deficient cells via inhibition of both rapamycin-sensitive and -insensitive pathways. | Molecular cancer therapeutics 20050601 |
| Drug coated stents for carotid intervention. | The Journal of cardiovascular surgery 20050601 |
| Delayed renal graft function: the influence of immunosuppression. | Transplantation proceedings 20050601 |
| Toward the definition of immunosuppressive regimens with antitumor activity. | Transplantation proceedings 20050601 |
| Successful use of sirolimus in a patient with bulky ovarian metastasis of hepatocellular carcinoma after liver transplantation. | Transplantation proceedings 20050601 |
| De novo immunosuppression with sirolimus and tacrolimus in heart transplant recipients compared with cyclosporine and mycophenolate mofetil: a one-year follow-up analysis. | Transplantation proceedings 20050601 |
| Cyclosporine and sirolimus interaction in a kidney transplant patient. | Transplantation proceedings 20050601 |
| [Advances in adjunctive pharmacological therapy for percutaneous coronary interventions]. | Revista espanola de cardiologia 20050601 |
| Placement of a sirolimus-coated stent in the distal left internal mammary artery of an 8-year-old boy. | The Journal of invasive cardiology 20050601 |
| The present and future of drug-eluting stents. | Italian heart journal : official journal of the Italian Federation of Cardiology 20050601 |
| Restenosis treatment in the drug-eluting stent era. | Italian heart journal : official journal of the Italian Federation of Cardiology 20050601 |
| Rapamycin pre-treatment preserves viability, ATP level and catabolic capacity during carbon starvation of Saccharomyces cerevisiae. | Yeast (Chichester, England) 20050601 |
| [Experimental study of Mytrolimus-eluting stents on preventing restenosis in porcine coronary model]. | Zhonghua xin xue guan bing za zhi 20050601 |
| Drug eluting stents in acute myocardial infarction. | Panminerva medica 20050601 |
| The solution structure of the FATC domain of the protein kinase target of rapamycin suggests a role for redox-dependent structural and cellular stability. | The Journal of biological chemistry 20050527 |
| Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito. | The Journal of biological chemistry 20050527 |
| The rapamycin analog CCI-779 is a potent inhibitor of pancreatic cancer cell proliferation. | Biochemical and biophysical research communications 20050527 |
| Response to 'Exceptional circumstances and heart transplantation' letter. | The New Zealand medical journal 20050520 |
| Withdrawal of immunosuppression contributing to the remission of malignant melanoma: a case report. | Cancer immunity 20050519 |
| Multiple overlapping drug-eluting stents to treat diffuse disease of the left anterior descending coronary artery. | Journal of the American College of Cardiology 20050517 |
| Cyclosporin A and tacrolimus, but not rapamycin, inhibit MHC-restricted antigen presentation pathways in dendritic cells. | Blood 20050515 |
| Ryanodine receptor subtype 2 encodes Ca2+ oscillations activated by acetylcholine via the M2 muscarinic receptor/cADP-ribose signalling pathway in duodenum myocytes. | Journal of cell science 20050515 |
| Comparison of thrombosis and restenosis risk from stent length of sirolimus-eluting stents versus bare metal stents. | The American journal of cardiology 20050515 |
| Drug-eluting stents versus bare metal stents in percutaneous coronary interventions (a meta-analysis). | The American journal of cardiology 20050515 |
| Comparison of C-reactive protein levels before and after coronary stenting and restenosis among patients treated with sirolimus-eluting versus bare metal stents. | The American journal of cardiology 20050515 |
| Intravascular ultrasound stent area of sirolimus-eluting stents and its impact on late outcome. | The American journal of cardiology 20050515 |
| Reduction in calcineurin inhibitor exposure and maintenance of effective immunosuppression: clinical experience with everolimus (Certican). | Transplantation 20050515 |
| Introducing everolimus (Certican) in organ transplantation: an overview of preclinical and early clinical developments. | Transplantation 20050515 |
| Concentration-controlled everolimus (Certican): combination with reduced dose calcineurin inhibitors. | Transplantation 20050515 |
| Clinical experience with everolimus (Certican): optimizing dose and tolerability. | Transplantation 20050515 |
| Clinical experience with everolimus (Certican) in elderly recipients: the 'old-for-old' concept. | Transplantation 20050515 |
| Clinical experience with everolimus (Certican) in young renal transplant recipients. | Transplantation 20050515 |
| Clinical experience with everolimus (Certican): a summary. | Transplantation 20050515 |
| Sourcing a chemical succession for cyclosporin from parasites and human pathogens. | Drug discovery today 20050515 |
| The efficacy of sirolimus- and paclitaxel-eluting stents: a meta-analysis of randomized controlled trials. | The Canadian journal of cardiology 20050515 |
| Four-year angiographic and intravascular ultrasound follow-up of patients treated with sirolimus-eluting stents. | Circulation 20050510 |
| Insulin stimulates postsynaptic density-95 protein translation via the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway. | The Journal of biological chemistry 20050506 |
| Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax : Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity. | Oncogene 20050505 |
| Tirofiban and sirolimus-eluting stent vs abciximab and bare-metal stent for acute myocardial infarction: a randomized trial. | JAMA 20050504 |
| Incidence, predictors, and outcome of thrombosis after successful implantation of drug-eluting stents. | JAMA 20050504 |
| Drug-eluting stents in acute myocardial infarction: is science catching up with practice? | JAMA 20050504 |
| Catalase induced expression of inflammatory mediators via activation of NF-kappaB, PI3K/AKT, p70S6K, and JNKs in BV2 microglia. | Cellular signalling 20050501 |
| Trans-10,cis-12 CLA increases adipocyte lipolysis and alters lipid droplet-associated proteins: role of mTOR and ERK signaling. | Journal of lipid research 20050501 |
| Sirolimus rescue of renal failure in children after combined liver-kidney transplantation. | Pediatric nephrology (Berlin, Germany) 20050501 |
| Combination therapy with sirolimus (rapamycin) and tacrolimus (FK-506) in treatment of refractory minimal change nephropathy, a clinical case report. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050501 |
| Effect of a fermented ginseng extract, BST204, on the expression of cyclooxygenase-2 in murine macrophages. | International immunopharmacology 20050501 |
| Role of mammalian target of rapamycin signaling in compensatory renal hypertrophy. | Journal of the American Society of Nephrology : JASN 20050501 |
| Simultaneous kissing drug-eluting stent technique for percutaneous treatment of bifurcation lesions in large-size vessels. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050501 |
| Warfarin or low-molecular-weight heparin therapy does not prolong pig-to-primate cardiac xenograft function. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501 |
| IDEC-131 (anti-CD154), sirolimus and donor-specific transfusion facilitate operational tolerance in non-human primates. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501 |
| Rapamycin successfully treats post-transplant autoimmune hepatitis. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501 |
| Preservation of renal structure and function at 2 years without calcineurin inhibitor use. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050501 |
| Effect of different immunosuppressive therapies on the lipid pattern in kidney-transplanted rats. | Transplant international : official journal of the European Society for Organ Transplantation 20050501 |
| Inter-laboratory differences in sirolimus results from six sirolimus testing centers using HPLC tandem mass spectrometry (LC/MS/MS). | Clinica chimica acta; international journal of clinical chemistry 20050501 |
| Blood concentrations of everolimus are markedly increased by ketoconazole. | Journal of clinical pharmacology 20050501 |
| IL-2 increases human telomerase reverse transcriptase activity transcriptionally and posttranslationally through phosphatidylinositol 3'-kinase/Akt, heat shock protein 90, and mammalian target of rapamycin in transformed NK cells. | Journal of immunology (Baltimore, Md. : 1950) 20050501 |
| Inhibition of mammalian target of rapamycin potentiates thrombin-induced intercellular adhesion molecule-1 expression by accelerating and stabilizing NF-kappa B activation in endothelial cells. | Journal of immunology (Baltimore, Md. : 1950) 20050501 |
| Insulin and IGF-I stimulate the formation of the eukaryotic initiation factor 4F complex and protein synthesis in C2C12 myotubes independent of availability of external amino acids. | The Journal of endocrinology 20050501 |
| PWT-458, a novel pegylated-17-hydroxywortmannin, inhibits phosphatidylinositol 3-kinase signaling and suppresses growth of solid tumors. | Cancer biology & therapy 20050501 |
| Mucositis after allogeneic hematopoietic stem cell transplantation: a cohort study of methotrexate- and non-methotrexate-containing graft-versus-host disease prophylaxis regimens. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050501 |
| A fast and simple high-performance liquid chromatography/mass spectrometry method for simultaneous measurement of whole blood tacrolimus and sirolimus. | Archives of pathology & laboratory medicine 20050501 |
| Use of a sirolimus-eluting stent to treat failure of a nonpolymer release paclitaxel-eluting stent implanted for in-stent restenosis. | The Journal of invasive cardiology 20050501 |
| Replicating oncolytic virus therapeutics - Third International Meeting. | IDrugs : the investigational drugs journal 20050501 |
| Sirolimus does double duty after organ transplantation. | The Lancet. Oncology 20050501 |
| Clinical and cost-effectiveness of newer immunosuppressive regimens in renal transplantation: a systematic review and modelling study. | Health technology assessment (Winchester, England) 20050501 |
| Effects of calcineurin inhibitors on sirolimus pharmacokinetics during staggered administration in renal transplant recipients. | Pharmacotherapy 20050501 |
| Inhibiting phosphoinositide 3-kinases. | Cancer biology & therapy 20050501 |
| Preservation of renal function after heart transplantation: initial single-center experience with sirolimus. | Transplantation proceedings 20050501 |
| Lipid metabolism in renal transplant patients receiving tacrolimus/sirolimus combination therapy. | Transplantation proceedings 20050501 |
| Effects of rapamycin on the arterial inflammatory response in atherosclerotic plaques in Apo-E knockout mice. | Transplantation proceedings 20050501 |
| Successful conversion to rapamycin for calcineurin inhibitor-related neurotoxicity following liver transplantation. | Transplantation proceedings 20050501 |
| Gonadal function and immunosuppressive therapy after renal transplantation. | Transplantation proceedings 20050501 |
| Severe hearing loss after liver transplantation. | Transplantation proceedings 20050501 |
| [Impact of coronary sirolimus-eluting stents on long-term outcome in diabetic patients]. | Zhonghua xin xue guan bing za zhi 20050501 |
| [Clinical and angiographic follow-up study of sirolimus-eluting stent for treatment of in-stent restenosis]. | Zhonghua xin xue guan bing za zhi 20050501 |
| [Rapamycin]. | Nihon rinsho. Japanese journal of clinical medicine 20050501 |
| Rapamycin ameliorates experimental autoimmune myocarditis. | International heart journal 20050501 |
| Assessment of microvascular perfusion changes in a rat breast tumor model using SonoVue to monitor the effects of different anti-angiogenic therapies. | Academic radiology 20050501 |
| Delayed occurrence of restenosis in drug eluting stents: an evidence of delayed healing. | The Journal of the Association of Physicians of India 20050501 |
| TOR kinase pathway and 14-3-3 proteins regulate glucose-induced expression of HXT1, a yeast low-affinity glucose transporter. | Yeast (Chichester, England) 20050430 |
| Effects of immunosuppressants on induction of regulatory cells after intratracheal delivery of alloantigen. | Transplantation 20050427 |
| The effect of 2-gram versus 1-gram concentration controlled mycophenolate mofetil on renal transplant outcomes using sirolimus-based calcineurin inhibitor drug-free immunosuppression. | Transplantation 20050427 |
| Immunosuppressive therapy with everolimus can be associated with potentially life-threatening lingual angioedema. | Transplantation 20050427 |
| Impact of sirolimus on early graft function after deceased-donor kidney transplantation. | Transplantation 20050427 |
| Elucidating the substrate specificity and condensation domain activity of FkbP, the FK520 pipecolate-incorporating enzyme. | Biochemistry 20050426 |
| Letter regarding article by Sawhney et al, 'treatment of left anterior descending coronary artery disease with sirolimus-eluting stents'. | Circulation 20050426 |
| Effectiveness and safety of sirolimus-eluting stents in the treatment of restenosis after coronary stent placement. | Circulation 20050426 |
| Zinc induces neurofilament phosphorylation independent of p70 S6 kinase in N2a cells. | Neuroreport 20050425 |
| The yeast eIF4E-associated protein Eap1p attenuates GCN4 translation upon TOR-inactivation. | FEBS letters 20050425 |
| [Hemosiderophages in respiratory secretions. Biological significance and clinical utility]. | Medicina clinica 20050423 |
| Activation of a phytopathogenic bacterial effector protein by a eukaryotic cyclophilin. | Science (New York, N.Y.) 20050422 |
| Pharmacokinetics of the immunosuppressant everolimus in maintenance renal transplant patients. | European journal of medical research 20050420 |
| Cost-effectiveness of drug-eluting stents: if only all things were equal. | The Medical journal of Australia 20050418 |
| Phosphorylated osteopontin promotes migration of human choriocarcinoma cells via a p70 S6 kinase-dependent pathway. | Journal of cellular biochemistry 20050415 |
| Complete remission of postransplant lung metastases from hepatocellular carcinoma under therapy with sirolimus and mycophenolate mofetil. | Transplantation 20050415 |
| Inhibition of mammalian target of rapamycin reverses alveolar epithelial neoplasia induced by oncogenic K-ras. | Cancer research 20050415 |
| Synergistic augmentation of rapamycin-induced autophagy in malignant glioma cells by phosphatidylinositol 3-kinase/protein kinase B inhibitors. | Cancer research 20050415 |
| The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation. | The Journal of biological chemistry 20050408 |
| Adjusted indirect comparison of intracoronary drug-eluting stents: evidence from a metaanalysis of randomized bare-metal-stent-controlled trials. | International journal of cardiology 20050408 |
| Characterization of the FKBP.rapamycin.FRB ternary complex. | Journal of the American Chemical Society 20050406 |
| Treatment of saphenous vein graft lesions with drug-eluting stents: immediate and midterm outcome. | Journal of the American College of Cardiology 20050405 |
| Stent underexpansion and residual reference segment stenosis are related to stent thrombosis after sirolimus-eluting stent implantation: an intravascular ultrasound study. | Journal of the American College of Cardiology 20050405 |
| The unrestricted use of paclitaxel- versus sirolimus-eluting stents for coronary artery disease in an unselected population: one-year results of the Taxus-Stent Evaluated at Rotterdam Cardiology Hospital (T-SEARCH) registry. | Journal of the American College of Cardiology 20050405 |
| Strain-induced vascular endothelial cell proliferation requires PI3K-dependent mTOR-4E-BP1 signal pathway. | American journal of physiology. Heart and circulatory physiology 20050401 |
| The impact of the introduction of drug-eluting stents on the clinical practice of surgical and percutaneous treatment of coronary artery disease. | European heart journal 20050401 |
| Inhibition of neointima formation by a novel drug-eluting stent system that allows for dose-adjustable, multiple, and on-site stent coating. | Arteriosclerosis, thrombosis, and vascular biology 20050401 |
| The Snf1 protein kinase and Sit4 protein phosphatase have opposing functions in regulating TATA-binding protein association with the Saccharomyces cerevisiae INO1 promoter. | Genetics 20050401 |
| mTOR-targeted therapy of cancer with rapamycin derivatives. | Annals of oncology : official journal of the European Society for Medical Oncology 20050401 |
| Therapeutic drug monitoring for everolimus in kidney transplantation using 12-month exposure, efficacy, and safety data. | Clinical transplantation 20050401 |
| The effect of sirolimus on sex hormone levels of male renal transplant recipients. | Clinical transplantation 20050401 |
| Rapamycin in patients with chronic renal allograft dysfunction. | Clinical transplantation 20050401 |
| Gastrointestinal hemorrhage due to complicated gastroduodenal ulcer disease in liver transplant patients taking sirolimus. | Clinical transplantation 20050401 |
| Cytomegalovirus prophylaxis with valganciclovir in African-American renal allograft recipients based on donor/recipient serostatus. | Clinical transplantation 20050401 |
| Selectin blockade plus therapy with low-dose sirolimus and cyclosporin a prevent brain death-induced renal allograft dysfunction. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050401 |
| Assessing analytical specificity in quantitative analysis using tandem mass spectrometry. | Clinical biochemistry 20050401 |
| One year cost effectiveness of sirolimus eluting stents compared with bare metal stents in the treatment of single native de novo coronary lesions: an analysis from the RAVEL trial. | Heart (British Cardiac Society) 20050401 |
| Unusual post-transplantation recurrence of focal segmental glomerulosclerosis which resolved with cyclosporine but not with sirolimus. | Transplant international : official journal of the European Society for Organ Transplantation 20050401 |
| Certican (Everolimus) in heart transplantation: from clinical trial to clinical experience. Proceedings of a meeting, Vienna, Austria, September 9, 2004. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401 |
| From clinical trials to clinical practice: an overview of Certican (everolimus) in heart transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401 |
| Prevention of cardiac allograft vasculopathy with Certican (everolimus): the Stanford University experience within the Certican Phase III clinical trial. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401 |
| Recommendations for use of Certican (everolimus) after heart transplantation: results from a German and Austrian Consensus Conference. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401 |
| Clinical experience with Certican (everolimus) in de novo heart transplant patients at the Deutsches Herzzentrum Berlin. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401 |
| Clinical experience with Certican (everolimus) in maintenance heart transplant patients at the Medical University of Vienna. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401 |
| Use of sirolimus and low-dose calcineurin inhibitor in lung transplant recipients with renal impairment: results of a controlled pilot study. | Kidney international 20050401 |
| Rapid response to rituximab in a pediatric liver transplant recipient with post-transplant lymphoproliferative disease and maintenance with sirolimus monotherapy. | Pediatric transplantation 20050401 |
| Efficacy and safety of oral sirolimus to inhibit in-stent intimal hyperplasia. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401 |
| Another attempt to deal with restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401 |
| Drug eluting stents: case study in the acceptance of a new medical technology. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401 |
| Results and follow-up after implantation of four or more sirolimus-eluting stents in the same patient. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050401 |
| Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets. | Diabetes 20050401 |
| Effective use of liquid chromatography-mass spectrometry (LC/MS) in the routine clinical laboratory for monitoring sirolimus, tacrolimus, and cyclosporine. | Therapeutic drug monitoring 20050401 |
| Validation of a practical liquid chomatography with ultraviolet detection method for quantification of whole-blood everolimus in a clinical TDM laboratory. | Therapeutic drug monitoring 20050401 |
| Successful use in lung transplantation of an immunosuppressive regimen aimed at reducing target blood levels of sirolimus and tacrolimus. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050401 |
| Kidney transplantation under minimal immunosuppression after pretransplant lymphoid depletion with Thymoglobulin or Campath. | Journal of the American College of Surgeons 20050401 |
| Proteomic analysis reveals hyperactivation of the mammalian target of rapamycin pathway in neurofibromatosis 1-associated human and mouse brain tumors. | Cancer research 20050401 |
| Effects of the mammalian target of rapamycin inhibitor CCI-779 used alone or with chemotherapy on human prostate cancer cells and xenografts. | Cancer research 20050401 |
| Treatment of psoriasis with topical sirolimus: preclinical development and a randomized, double-blind trial. | The British journal of dermatology 20050401 |
| [Islet cell transplantation]. | Nihon rinsho. Japanese journal of clinical medicine 20050401 |
| Sirolimus improves renal function in cardiac transplantation. | Transplantation proceedings 20050401 |
| Graft function, cardiovascular risk factors, and sex hormones in renal transplant recipients on an immunosuppressive regimen of everolimus, reduced dose of cyclosporine, and basiliximab. | Transplantation proceedings 20050401 |
| [Research progress of the drug-coated stents]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20050401 |
| Right atrial thrombosis in a heart transplant recipient after initiation of sirolimus. | Acta cardiologica 20050401 |
| Drug-eluting stents. The third revolution in percutaneous coronary intervention. | Italian heart journal : official journal of the Italian Federation of Cardiology 20050401 |
| mTOR promotes survival and astrocytic characteristics induced by Pten/AKT signaling in glioblastoma. | Neoplasia (New York, N.Y.) 20050401 |
| Macrophages rapidly transfer pathogens from lipid raft vacuoles to autophagosomes. | Autophagy 20050401 |
| Sirolimus for Kaposi's sarcoma in renal-transplant recipients. | The New England journal of medicine 20050331 |
| Immunosuppressive drugs and the risk of cancer after organ transplantation. | The New England journal of medicine 20050331 |
| Effect of GLP-1 on glucose transport and its cell signalling in human myocytes. | Regulatory peptides 20050330 |
| Design of an intein that can be inhibited with a small molecule ligand. | Journal of the American Chemical Society 20050330 |
| Sirolimus-eluting stents to abolish intimal hyperplasia and improve flow in porcine arteriovenous grafts: a 4-week follow-up study. | Circulation 20050329 |
| Drug interaction between itraconazole and sirolimus in a primary renal allograft recipient. | Transplantation 20050327 |
| Cyclin D1 and c-myc internal ribosome entry site (IRES)-dependent translation is regulated by AKT activity and enhanced by rapamycin through a p38 MAPK- and ERK-dependent pathway. | The Journal of biological chemistry 20050325 |
| Characterization of a conserved C-terminal motif (RSPRR) in ribosomal protein S6 kinase 1 required for its mammalian target of rapamycin-dependent regulation. | The Journal of biological chemistry 20050325 |
| The mTOR inhibitor RAD001 sensitizes tumor cells to DNA-damaged induced apoptosis through inhibition of p21 translation. | Cell 20050325 |
| Short- and long-term clinical outcome after drug-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: insights from the Rapamycin-Eluting and Taxus Stent Evaluated At Rotterdam Cardiology Hospital registries (RESEARCH and T-SEARCH). | Circulation 20050322 |
| [Study of the effects of immunosuppressive agents on human islet cells in vitro]. | Zhonghua yi xue za zhi 20050316 |
| Antileukemic activity of rapamycin in acute myeloid leukemia. | Blood 20050315 |
| Comparison of C-reactive protein levels after coronary stenting with bare metal versus sirolimus-eluting stents. | The American journal of cardiology 20050315 |
| In-hospital and nine-month outcome of treatment of coronary bifurcational lesions with sirolimus-eluting stent. | The American journal of cardiology 20050315 |
| Thirty-day incidence and six-month clinical outcome of thrombotic stent occlusion after bare-metal, sirolimus, or paclitaxel stent implantation. | Journal of the American College of Cardiology 20050315 |
| Drug-eluting stent thrombosis: results from a pooled analysis including 10 randomized studies. | Journal of the American College of Cardiology 20050315 |
| Rapamycin inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma. | Cancer research 20050315 |
| A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050315 |
| [Successful treatment of a severe case of idiopathic pulmonary fibrosis with rapamycin]. | Medizinische Klinik (Munich, Germany : 1983) 20050315 |
| Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth. | World journal of gastroenterology 20050314 |
| Clinical and angiographic follow-up study of sirolimus-eluting stent for treatment of in-stent restenosis. | Chinese medical journal 20050305 |
| Resistance exercise increases muscle protein synthesis and translation of eukaryotic initiation factor 2Bepsilon mRNA in a mammalian target of rapamycin-dependent manner. | The Journal of biological chemistry 20050304 |
| Activation of the mammalian target of rapamycin pathway acutely inhibits insulin signaling to Akt and glucose transport in 3T3-L1 and human adipocytes. | Endocrinology 20050301 |
| Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models. | Genes, chromosomes & cancer 20050301 |
| HMG-CoA reductase inhibitors, statins, induce phosphorylation of Mdm2 and attenuate the p53 response to DNA damage. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050301 |
| Mouse embryonic stem cells and preimplantation embryos require signaling through the phosphatidylinositol 3-kinase pathway to suppress apoptosis. | Molecular reproduction and development 20050301 |
| Small molecule control of pre-mRNA splicing. | RNA (New York, N.Y.) 20050301 |
| Everolimus and basiliximab permit suppression by human CD4+CD25+ cells in vitro. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050301 |
| Consequences of genetic polymorphisms for sirolimus requirements after renal transplant in patients on primary sirolimus therapy. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050301 |
| Constitutive activation of phosphatidyl-inositide 3 kinase contributes to the survival of Hodgkin's lymphoma cells through a mechanism involving Akt kinase and mTOR. | The Journal of pathology 20050301 |
| Mechanism of zinc-induced phosphorylation of p70 S6 kinase and glycogen synthase kinase 3beta in SH-SY5Y neuroblastoma cells. | Journal of neurochemistry 20050301 |
| Immunosuppression in liver transplantation: beyond calcineurin inhibitors. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20050301 |
| Meta-analysis comparing drug-eluting stents with bare metal stents. | The American journal of cardiology 20050301 |
| Maintenance of long-term clinical benefit with sirolimus-eluting coronary stents: three-year results of the RAVEL trial. | Circulation 20050301 |
| Activity of sirolimus in patients with myelodysplastic syndrome--results of a pilot study. | British journal of haematology 20050301 |
| Clinical application of sirolimus in renal transplantation: an update. | Transplant international : official journal of the European Society for Organ Transplantation 20050301 |
| Sirolimus quantification by high-performance liquid chromatography with ultraviolet detection. | Transplant international : official journal of the European Society for Organ Transplantation 20050301 |
| Efficacy of rapamycin in patient with juvenile rheumatoid arthritis. | Transplant international : official journal of the European Society for Organ Transplantation 20050301 |
| Firefly luciferase enzyme fragment complementation for imaging in cells and living animals. | Analytical chemistry 20050301 |
| Novel site-specific systemic delivery of Rapamycin with perfluorobutane gas microbubble carrier reduced neointimal formation in a porcine coronary restenosis model. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050301 |
| Late follow-up from RAVEL: transition from intention to observation. | Circulation 20050301 |
| Sirolimus-eluting stent treatment for isolated proximal left anterior descending artery stenoses. Results from the prospective multi-center German Cypher Registry. | Zeitschrift fur Kardiologie 20050301 |
| Role of glycogen synthase kinase 3beta in rapamycin-mediated cell cycle regulation and chemosensitivity. | Cancer research 20050301 |
| Sirolimus-eluting stents versus the superficial femoral artery: second round. | Journal of vascular and interventional radiology : JVIR 20050301 |
| Sirolimus-eluting versus bare nitinol stent for obstructive superficial femoral artery disease: the SIROCCO II trial. | Journal of vascular and interventional radiology : JVIR 20050301 |
| [Treatment of lesions with a high risk of stenosis. Comparative study in 300 patients of rapamycin- and Paclitaxel-eluting polymer-based stents, and bare metal stents]. | Revista espanola de cardiologia 20050301 |
| Rapamycin and UCN-01 synergistically induce apoptosis in human leukemia cells through a process that is regulated by the Raf-1/MEK/ERK, Akt, and JNK signal transduction pathways. | Molecular cancer therapeutics 20050301 |
| Restenosis and drug-eluting stents. | The Mount Sinai journal of medicine, New York 20050301 |
| LY294002 and rapamycin co-operate to inhibit T-cell proliferation. | British journal of pharmacology 20050301 |
| Effect of multiple-dose erythromycin on everolimus pharmacokinetics. | European journal of clinical pharmacology 20050301 |
| A combination of anergic cells' adoptive transfer and rapamycin therapy prolongs cardiac allograft survival in mice. | Scandinavian journal of immunology 20050301 |
| Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation. | Endocrine-related cancer 20050301 |
| Sirolimus: a new option in transplantation. | Expert opinion on pharmacotherapy 20050301 |
| Recurrence of migraine with aura due to tacrolimus therapy in a liver transplant recipient successfully treated with sirolimus substitution. | Headache 20050301 |
| Sirolimus in pediatric renal transplantation. | Transplantation proceedings 20050301 |
| Sirolimus-based therapy with or without cyclosporine: long-term follow-up in renal transplant patients. | Transplantation proceedings 20050301 |
| A randomized trial of steroid avoidance in renal transplant patients treated with everolimus and cyclosporine. | Transplantation proceedings 20050301 |
| Corticosteroid avoidance ameliorates lymphocele formation and wound healing complications associated with sirolimus therapy. | Transplantation proceedings 20050301 |
| Rabbit antithymocyte globulin: a postoperative risk factor for sirolimus-treated renal transplant patients? | Transplantation proceedings 20050301 |
| Addition of sirolimus to cyclosporine in long-term kidney transplant recipients to withdraw steroid. | Transplantation proceedings 20050301 |
| The effect of rapamycin on the healing of the ureteric anastomosis and wound healing. | Transplantation proceedings 20050301 |
| Effect of rapamycin on the healing of the bile duct. | Transplantation proceedings 20050301 |
| Severe limb lymphedema in sirolimus-treated patients. | Transplantation proceedings 20050301 |
| Cyclosporine and rapamycin act in a synergistic and dose-dependent manner in a model of immunosuppressant-induced kidney damage. | Transplantation proceedings 20050301 |
| Sirolimus delays recovery from posttransplant renal failure in kidney graft recipients. | Transplantation proceedings 20050301 |
| Pharmacokinetics of mycophenolic acid in kidney transplant patients receiving sirolimus versus cyclosporine. | Transplantation proceedings 20050301 |
| No-load sirolimus with tacrolimus and steroids is safe and effective in renal transplantation. | Transplantation proceedings 20050301 |
| Regression of Kaposi's sarcoma in renal graft recipients after conversion to sirolimus treatment. | Transplantation proceedings 20050301 |
| Graft survival and immune regulation of pancreas allograft recipients induced with thymoglobulin, sirolimus, and cyclosporine. | Transplantation proceedings 20050301 |
| Impact of a sirolimus/tacrolimus-based immunosuppressive regimen on kidney function after islet transplantation. | Transplantation proceedings 20050301 |
| Evidence for down-regulation of phosphoinositide 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR)-dependent translation regulatory signaling pathways in Ames dwarf mice. | The journals of gerontology. Series A, Biological sciences and medical sciences 20050301 |
| Primary stenting of occluded native coronary arteries II--rationale and design of the PRISON II study: a randomized comparison of bare metal stent implantation with sirolimus-eluting stent implantation for the treatment of chronic total coronary occlusions. | American heart journal 20050301 |
| Cutaneous adverse events in renal transplant recipients receiving sirolimus-based therapy. | Transplantation 20050227 |
| High-performance liquid chromatography with ultraviolet detection for therapeutic drug monitoring of everolimus. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225 |
| Potent inhibitory effect of sirolimus on circulating vascular progenitor cells. | Circulation 20050222 |
| [Recent progress and problems in percutaneous coronary intervention]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050220 |
| Specific interactions of PP2A and PP2A-like phosphatases with the yeast PTPA homologues, Ypa1 and Ypa2. | The Biochemical journal 20050215 |
| Activation of the p70 S6 kinase by all-trans-retinoic acid in acute promyelocytic leukemia cells. | Blood 20050215 |
| Long-term pharmacologically regulated expression of erythropoietin in primates following AAV-mediated gene transfer. | Blood 20050215 |
| Intravascular ultrasound assessment of lesions with target vessel failure after sirolimus-eluting stent implantation. | The American journal of cardiology 20050215 |
| Early and mid-term results of drug-eluting stent implantation in unprotected left main. | Circulation 20050215 |
| Maintenance immunosuppression use and the associated risk of avascular necrosis after kidney transplantation in the United States. | Transplantation 20050215 |
| Drug-eluting stents for diabetes mellitus: a rush to judgment? | Journal of the American College of Cardiology 20050215 |
| Exceptional circumstances and heart transplantation. | The New Zealand medical journal 20050211 |
| REDD1 integrates hypoxia-mediated survival signaling downstream of phosphatidylinositol 3-kinase. | Oncogene 20050210 |
| [New generation of percutaneous coronary intervention: drug-eluting stent]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20050210 |
| Scientists hopeful as they uncover molecular clues to prostate cancer. | Journal of the National Cancer Institute 20050202 |
| EGF receptor transactivation mediates ANG II-stimulated mitogenesis in intestinal epithelial cells through the PI3-kinase/Akt/mTOR/p70S6K1 signaling pathway. | American journal of physiology. Gastrointestinal and liver physiology 20050201 |
| Prevention of lethal acute GVHD with an agonistic CD28 antibody and rapamycin. | Blood 20050201 |
| Regulation of leucine uptake by tor1+ in Schizosaccharomyces pombe is sensitive to rapamycin. | Genetics 20050201 |
| Rapamycin attenuates vascular wall inflammation and progenitor cell promoters after angioplasty. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050201 |
| Application of commercial calibrators for the analysis of immunosuppressant drugs in whole blood. | Clinical chemistry 20050201 |
| Complete assignments of the 1H and 13C resonances of 40-epi-(N1-tetrazolyl)-rapamycin and revised 13C assignments for rapamycin. | Magnetic resonance in chemistry : MRC 20050201 |
| Effects of maternal starvation on hepatocyte proliferation in the late gestation fetal rat. | Pediatric research 20050201 |
| Rapamycin-treated, alloantigen-pulsed host dendritic cells induce ag-specific T cell regulation and prolong graft survival. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050201 |
| Inhibition of endogenous SHIP2 ameliorates insulin resistance caused by chronic insulin treatment in 3T3-L1 adipocytes. | Diabetologia 20050201 |
| Large coronary artery aneurysms following sirolimus eluting stent implantation. | Heart (British Cardiac Society) 20050201 |
| Economic evaluation of everolimus vs. azathioprine at one year after de novo heart transplantation. | Clinical transplantation 20050201 |
| An open-label, pilot study evaluating the safety and efficacy of converting from calcineurin inhibitors to sirolimus in established renal allograft recipients with moderate renal insufficiency. | Clinical transplantation 20050201 |
| Improved renal function in de novo renal transplant patients on sirolimus maintenance therapy following discontinuation of cyclosporine. | Therapeutic drug monitoring 20050201 |
| The portal immunosuppressive storm: relevance to islet transplantation? | Therapeutic drug monitoring 20050201 |
| Gastrointestinal leukocytoclastic vasculitis: an adverse effect of sirolimus. | Pediatric transplantation 20050201 |
| Inhibitory effect of rapamycin on corneal neovascularization in vitro and in vivo. | Investigative ophthalmology & visual science 20050201 |
| Indefinite survival of neonatal porcine islet xenografts by simultaneous targeting of LFA-1 and CD154 or CD45RB. | Diabetes 20050201 |
| Cypher drug-eluting stent treatment of tibioperoneal obstructive disease: a case report. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050201 |
| Beware the sirens' call. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050201 |
| Is overdilatation of 3.0 mm sirolimus-eluting stent associated with a higher restenosis rate? | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050201 |
| Sirolimus-eluting stent implantation for unprotected left main coronary artery stenosis: comparison with bare metal stent implantation. | Journal of the American College of Cardiology 20050201 |
| Percutaneous coronary intervention and drug-eluting stents. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201 |
| Economic evaluation of sirolimus-eluting stents. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201 |
| The dollars and sense of drug-eluting stents. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201 |
| Use of everolimus-eluting stent with a bioresorbable polymer coating for treatment of recurrent in-stent restenosis. | The Journal of invasive cardiology 20050201 |
| Rotational ablation of an unexpandable sirolimus-eluting stent. | The Journal of invasive cardiology 20050201 |
| Rapamycin rescue therapy in patients after kidney transplantation: first clinical experience. | Transplant international : official journal of the European Society for Organ Transplantation 20050201 |
| Rapamycin treatment is associated with an increased apoptosis rate in experimental vein grafts. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20050201 |
| Rapamycin (sirolimus) as a steroid-sparing agent in dermatomyositis. | Journal of the American Academy of Dermatology 20050201 |
| Sirolimus immunosuppression in pediatric heart transplant recipients: a single-center experience. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20050201 |
| How drug-eluting stents keep coronary blood flowing. | Nursing 20050201 |
| Transcriptional profiles in peripheral blood mononuclear cells prognostic of clinical outcomes in patients with advanced renal cell carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050201 |
| Tumor cell sensitization to apoptotic stimuli by selective inhibition of specific Akt/PKB family members. | Molecular cancer therapeutics 20050201 |
| Assessment of glomerular and tubular functions in renal transplant patients receiving cyclosporine A in combination with either sirolimus or everolimus. | Clinical nephrology 20050201 |
| PKB/Akt mediates radiosensitization by the signaling inhibitor LY294002 in human malignant gliomas. | Journal of neuro-oncology 20050201 |
| Stent competition helps prices. | Hospital material[dollar sign] management 20050201 |
| Patent infringement. | Nature reviews. Drug discovery 20050201 |
| Long-term inducible gene expression in the eye via adeno-associated virus gene transfer in nonhuman primates. | Human gene therapy 20050201 |
| Effects of rapamycin on the epithelial-to-mesenchymal transition of human peritoneal mesothelial cells. | The International journal of artificial organs 20050201 |
| Sirolimus-eluting stent implantation for chronic total occlusion of the left main coronary artery. | Journal of interventional cardiology 20050201 |
| Coronary restenosis after implantation of drug-eluting stents. | Minerva cardioangiologica 20050201 |
| Can oral sirolimus therapy prevent in-stent restenosis? | Nature clinical practice. Cardiovascular medicine 20050201 |
| Sirolimus and ACE-inhibitors: a note of caution. | Transplantation 20050127 |
| Relationship of late loss in lumen diameter to coronary restenosis in sirolimus-eluting stents. | Circulation 20050125 |
| Alternative phospholipase D/mTOR survival signal in human breast cancer cells. | Oncogene 20050120 |
| A prospective randomized comparison between paclitaxel and sirolimus stents in the real world of interventional cardiology: the TAXi trial. | Journal of the American College of Cardiology 20050118 |
| Altered trafficking of CD8+ memory T cells after implantation of rapamycin-eluting stents in patients with coronary artery disease. | Immunology letters 20050115 |
| Impact of sirolimus-eluting stent on the outcome of patients with chronic total occlusions. | The American journal of cardiology 20050115 |
| Impact of baseline renal function on mortality after percutaneous coronary intervention with sirolimus-eluting stents or bare metal stents. | The American journal of cardiology 20050115 |
| Interleukin-12-induced interferon-gamma production by human peripheral blood T cells is regulated by mammalian target of rapamycin (mTOR). | The Journal of biological chemistry 20050114 |
| Sirolimus-eluting stent or paclitaxel-eluting stent vs balloon angioplasty for prevention of recurrences in patients with coronary in-stent restenosis: a randomized controlled trial. | JAMA 20050112 |
| [Nephrology]. | Revue medicale suisse 20050105 |
| Direct stenting of native de novo coronary artery lesions with the sirolimus-eluting stent: a post hoc subanalysis of the pooled E- and C-SIRIUS trials. | Journal of the American College of Cardiology 20050104 |
| Effects of rapamycin on cardiac and skeletal muscle contraction and crossbridge cycling. | The Journal of pharmacology and experimental therapeutics 20050101 |
| Thyroid hormone induces rapid activation of Akt/protein kinase B-mammalian target of rapamycin-p70S6K cascade through phosphatidylinositol 3-kinase in human fibroblasts. | Molecular endocrinology (Baltimore, Md.) 20050101 |
| An intramolecular ionic hydrogen bond stabilizes a cis amide bond rotamer of a ring-opened rapamycin-degradation product. | Magnetic resonance in chemistry : MRC 20050101 |
| Effects of rapamycin in the Eker rat model of tuberous sclerosis complex. | Pediatric research 20050101 |
| Rapamycin markedly slows disease progression in a rat model of polycystic kidney disease. | Journal of the American Society of Nephrology : JASN 20050101 |
| Monitoring of immunosuppressive therapy in renal transplanted patients. | Contributions to nephrology 20050101 |
| Decreased Cytomegalovirus infection after antilymphocyte therapy in sirolimus-treated renal transplant patients. | International immunopharmacology 20050101 |
| Nonnephrotoxic immunosuppression in patients after liver transplantation. | International immunopharmacology 20050101 |
| Center experience in liver transplantation (LTX): management of dermal side effects caused by sirolimus. | International immunopharmacology 20050101 |
| Immunosuppressant drug monitoring: is the laboratory meeting clinical expectations? | The Annals of pharmacotherapy 20050101 |
| A meta-analysis of clinical trials of paclitaxel- and sirolimus-eluting stents in patients with obstructive coronary artery disease. | British journal of clinical pharmacology 20050101 |
| Immunosuppression: towards a logical approach in liver transplantation. | Clinical and experimental immunology 20050101 |
| CD28 regulates the translation of Bcl-xL via the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway. | Journal of immunology (Baltimore, Md. : 1950) 20050101 |
| Strategies for minimizing immunosuppression in kidney transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20050101 |
| Early cyclosporine withdrawal from a sirolimus-based regimen results in better renal allograft survival and renal function at 48 months after transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20050101 |
| Dosing of rapamycin is critical to achieve an optimal antiangiogenic effect against cancer. | Transplant international : official journal of the European Society for Organ Transplantation 20050101 |
| Cardiovascular risk profile in patients treated with sirolimus after renal transplantation. | Kidney international. Supplement 20050101 |
| Sirolimus- and paclitaxel-eluting stents in comparison with balloon angioplasty for treatment of in-stent restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20050101 |
| Angiographic results of the first human experience with everolimus-eluting stents for the treatment of coronary lesions (the FUTURE I trial). | The American journal of cardiology 20050101 |
| Mammalian target of rapamycin (mTOR) inhibition in chronic lymphocytic B-cell leukemia: a new therapeutic option. | Leukemia & lymphoma 20050101 |
| A novel technique for on-capillary preconcentration of anionic compounds applied to the trace analysis of rapamycin in human blood by capillary electrophoresis. | Electrophoresis 20050101 |
| Rapamycin (sirolimus) for treatment of chronic graft-versus-host disease. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20050101 |
| Stent implantation activates RhoA in human arteries: inhibitory effect of rapamycin. | Journal of vascular research 20050101 |
| Nephrotoxicity of rapamycin: an emerging problem in clinical medicine. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050101 |
| De novo thrombotic microangiopathy following treatment with sirolimus: report of two cases. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050101 |
| Immunophilin ligands FK506 and cyclosporine A improve neurologic and histopathologic outcome after transient spinal cord ischemia in rabbits. | The Journal of thoracic and cardiovascular surgery 20050101 |
| A multicenter pilot study of early (4-day) steroid cessation in renal transplant recipients under simulect, tacrolimus and sirolimus. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050101 |
| Sirolimus impairs improvement of the gonadal function after renal transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20050101 |
| Population pharmacokinetics of CCI-779: correlations to safety and pharmacogenomic responses in patients with advanced renal cancer. | Clinical pharmacology and therapeutics 20050101 |
| Sirolimus-eluting stents for the treatment of atherosclerotic ostial lesions. | The Journal of invasive cardiology 20050101 |
| Sirolimus-eluting stents for the treatment of atherosclerotic ostial lesions. | The Journal of invasive cardiology 20050101 |
| Determining sensitivity to rapamycin and its analogues in breast cancer patients. | Breast cancer research : BCR 20050101 |
| Tor and cyclic AMP-protein kinase A: two parallel pathways regulating expression of genes required for cell growth. | Eukaryotic cell 20050101 |
| The Coronary Artery Revascularisation in Diabetes (CARDia) trial: background, aims, and design. | American heart journal 20050101 |
| Effects of conversion from sirolimus oral solution to tablets in stable Taiwanese renal transplant recipients. | Journal of the Formosan Medical Association = Taiwan yi zhi 20050101 |
| Choosing a drug-eluting stent: a comparison between CYPHER and TAXUS. | Reviews in cardiovascular medicine 20050101 |
| Safety and efficacy of drug-eluting stents. | Reviews in cardiovascular medicine 20050101 |
| Coping with rejection: immunosuppressants and organ transplantation. | Drug discovery today 20050101 |
| Benefit-risk assessment of sirolimus in renal transplantation. | Drug safety 20050101 |
| Sphingosine-1-phosphate-induced smooth muscle cell migration involves the mammalian target of rapamycin. | Journal of vascular surgery 20050101 |
| Mechanisms of action of rapamycin in gliomas. | Neuro-oncology 20050101 |
| Cardiovascular device development: drug-eluting stents and implantable devices for the treatment of heart failure--the view from the Circulatory System Advisory Panel. | American journal of therapeutics 20050101 |
| [New immunodepressant drugs for the prevention and control of kidney transplant rejection]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20050101 |
| Protein synthesis-dependent LTP in isolated dendrites of CA1 pyramidal cells. | Hippocampus 20050101 |
| Prograf produces a molecular environment favoring antifibrosis, an effect reversed by the addition of rapamune. | Transplantation proceedings 20050101 |
| Immunological evaluation of combination therapy with tacrolimus and sirolimus on long-term allograft survival in nonhuman primates. | Transplantation proceedings 20050101 |
| Predominant inhibition of interleukin-6 synthesis in patient-specific endothelial cells by mTOR inhibitors below a concentration range where cell proliferation is affected and mitotic arrest takes place. | Transplantation proceedings 20050101 |
| Sirolimus-mediated prolongation of rat cardiac allograft survival is enhanced by beta1 integrin very late antigen-4 blockade. | Transplantation proceedings 20050101 |
| Mycophenolate mofetil inhibits intimal hyperplasia and attenuates the expression of genes favouring smooth muscle cell proliferation and migration. | Transplantation proceedings 20050101 |
| A microparticle enzyme immunoassay to measure sirolimus. | Transplantation proceedings 20050101 |
| Involvement of mitogen-stimulated p70-S6 kinase in the development of sensitization to the methamphetamine-induced rewarding effect in rats. | Neuroscience 20050101 |
| Medium-term results from the clinical and angiographic follow-up of patients after angioplasty and implantation of sirolimus-eluting stents. | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101 |
| The use of drug-eluting stents in everyday clinical practice: can the results of randomised trials be achieved in the 'real world'? | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101 |
| Inhibition of different intracellular signal cascades in human pancreatic cancer cells. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20050101 |
| Inhibition of mTOR suppresses experimental liver tumours. | Anticancer research 20050101 |
| [The first experience with sirolimus (Rapamune) after kidney transplantation in Lithuania]. | Medicina (Kaunas, Lithuania) 20050101 |
| Sirolimus-eluting stents for treatment of in-stent restenosis: immediate and late results. | Texas Heart Institute journal 20050101 |
| Sirolimus increases tissue factor expression but not activity in cultured human vascular smooth muscle cells. | BMC cardiovascular disorders 20050101 |
| Percutaneous therapy of bifurcation lesions with drug-eluting stent implantation: the Culotte technique revisited. | International journal of cardiovascular interventions 20050101 |
| Therapeutic targeting of multiple signaling pathways in malignant pleural mesothelioma. | Oncology 20050101 |
| Sirolimus: the evidence for clinical pharmacokinetic monitoring. | Clinical pharmacokinetics 20050101 |
| Overcoming cisplatin resistance by mTOR inhibitor in lung cancer. | Molecular cancer 20050101 |
| Impaired glomerular and tubular function as a short-term effect of sirolimus treatment in the rat. | American journal of nephrology 20050101 |
| Lack of effect of rapamycin in anti-CCP antibody production in a rheumatoid arthritis kidney allograft recipient. | Clinical and experimental rheumatology 20050101 |
| Direct stenting with sirolimus-eluting stents. | The American heart hospital journal 20050101 |
| Treatment of double vessel coronary artery disease by totally endoscopic bypass surgery and drug-eluting stent placement in one simultaneous hybrid session. | The heart surgery forum 20050101 |
| Impressive regression of primary liver cancer after treatment with sirolimus. | Acta oncologica (Stockholm, Sweden) 20050101 |
| [Acute, idiopathic, bilateral uveitis with periphlebitis--case report]. | Klinika oczna 20050101 |
| Sirolimus- versus paclitaxel-eluting stent implantation for unprotected left main coronary artery stenosis. | Cardiology 20050101 |
| Treating breast cancer through novel inhibitors of the phosphatidylinositol 3'-kinase pathway. | Breast cancer research : BCR 20050101 |
| Calcineurin inhibitor-free immunosuppression in renal transplantation. | Transplantation proceedings 20050101 |
| Conversion to sirolimus in a population of kidney and kidney-pancreas transplant recipients. | Transplantation proceedings 20050101 |
| Combined use of tacrolimus and sirolimus in de novo renal transplant patients: current data. | Transplantation proceedings 20050101 |
| Is sirolimus responsible for proteinuria? | Transplantation proceedings 20050101 |
| Sirolimus-associated acute respiratory distress syndrome in a renal transplant recipient. | Transplantation proceedings 20050101 |
| Evaluation of a new immunoassay to measure sirolimus blood concentrations compared to a tandem mass-spectrometric chromatographic analysis. | Transplantation proceedings 20050101 |
| Determination of rapamycin: quantification of the sodiated species by an ion trap mass spectrometer as an alternative to the ammoniated complex analysis by triple quadrupole. | Rapid communications in mass spectrometry : RCM 20050101 |
| The mammalian target of the rapamycin (mTOR) kinase pathway: its role in tumourigenesis and targeted antitumour therapy. | Cellular & molecular biology letters 20050101 |
| [Evidences in immunosuppression in the maintenance of renal transplantation]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101 |
| Acute and intermediate-term procedural results using cypher stenting to treat multi-vessel coronary artery disease. | International journal of cardiovascular interventions 20050101 |
| Drug-eluting stents for the treatment of in-stent restenosis: a clinical review. | Cardiovascular revascularization medicine : including molecular interventions 20050101 |
| Segmental vessel wall shear stress and neointimal formation after sirolimus-eluting stent implantation: physiological insights in a porcine coronary model. | Cardiovascular revascularization medicine : including molecular interventions 20050101 |
| Sirolimus-induced acneiform eruption. | Dermatology (Basel, Switzerland) 20050101 |
| Drug-eluting stents: immediate and long-term results. | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101 |
| What is the best contemporary treatment for in-stent restenosis? | Cardiovascular revascularization medicine : including molecular interventions 20050101 |
| Drug-eluting stents for the treatment of in-stent restenosis--'real world' double centre experience in consecutive patients. | International journal of cardiovascular interventions 20050101 |
| Successful use of sirolimus-eluting stents for treatment of ST-elevation acute myocardial infarction caused by left main coronary artery occlusion. | Texas Heart Institute journal 20050101 |
| Long-term outcome after coronary angioplasty: where do we stand? | Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 20050101 |
| Effects of combined treatment with rapamycin and cotylenin A, a novel differentiation-inducing agent, on human breast carcinoma MCF-7 cells and xenografts. | Breast cancer research : BCR 20050101 |
| A case of giant aneurysm following percutaneous coronary intervention. | Indian heart journal 20050101 |
| [Immunosuppression for kidney transplant recipients: current strategies]. | Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20050101 |
| Rapamycin inhibits platelet-derived growth factor-induced collagen, but not fibronectin, synthesis in rat mesangial cells. | Yonsei medical journal 20041231 |
| A pilot study of calcineurin inhibitors (CNIs) and steroid avoidance immunosuppressive protocol among living donor kidney transplant recipients. | Yonsei medical journal 20041231 |
| TOR regulates ribosomal protein gene expression via PKA and the Forkhead transcription factor FHL1. | Cell 20041229 |
| Glucose-stimulated protein synthesis in pancreatic beta-cells parallels an increase in the availability of the translational ternary complex (eIF2-GTP.Met-tRNAi) and the dephosphorylation of eIF2 alpha. | The Journal of biological chemistry 20041224 |
| The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase. | The Journal of biological chemistry 20041224 |
| Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1. | Nature 20041223 |
| [Drug-eluting stents in coronary arteries. The risk of restenosis is drastically reduced]. | Lakartidningen 20041223 |
| Systemic rapamycin inhibits retinal and choroidal neovascularization in mice. | Molecular vision 20041222 |
| Quantitative assessment of angiographic restenosis after sirolimus-eluting stent implantation in native coronary arteries. | Circulation 20041221 |
| Drug therapy in the heart transplant recipient: part II: immunosuppressive drugs. | Circulation 20041221 |
| Autophagy is a defense mechanism inhibiting BCG and Mycobacterium tuberculosis survival in infected macrophages. | Cell 20041217 |
| In vivo antitumor effects of the mTOR inhibitor CCI-779 against human multiple myeloma cells in a xenograft model. | Blood 20041215 |
| Combination of the mTOR inhibitor rapamycin and CC-5013 has synergistic activity in multiple myeloma. | Blood 20041215 |
| Identification of filamin C as a new physiological substrate of PKBalpha using KESTREL. | The Biochemical journal 20041215 |
| Intravascular ultrasonic comparative analysis of degree of intimal hyperplasia produced by four different stents in the coronary arteries. | The American journal of cardiology 20041215 |
| mTOR and P70 S6 kinase expression in primary liver neoplasms. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041215 |
| Conjugation of an antibody to cross-linked fibrin for targeted delivery of anti-restenotic drugs. | Journal of controlled release : official journal of the Controlled Release Society 20041210 |
| Sirolimus-eluting vs uncoated stents for prevention of restenosis in small coronary arteries: a randomized trial. | JAMA 20041208 |
| Stenting small coronary arteries: works in progress. | JAMA 20041208 |
| PKC-eta mediates glioblastoma cell proliferation through the Akt and mTOR signaling pathways. | Oncogene 20041202 |
| Insulin facilitation of muscle protein synthesis following resistance exercise in hindlimb-suspended rats is independent of a rapamycin-sensitive pathway. | American journal of physiology. Endocrinology and metabolism 20041201 |
| Toxin-induced tail phosphorylation of hepatocellular S6 kinase: evidence for a dual involvement of the AMP-activated protein kinase in S6 kinase regulation. | Toxicological sciences : an official journal of the Society of Toxicology 20041201 |
| Apelin (65-77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041201 |
| Dyslipidemia during sirolimus therapy in patients after liver transplantation. | Clinical transplantation 20041201 |
| Fate of donor kidney: laparoscopic versus open technique. | The Journal of urology 20041201 |
| Which parameter should be chosen as primary endpoint for randomized drug-eluting stent studies? | Journal of interventional cardiology 20041201 |
| Clinical experiences using everolimus-eluting stents in patients with coronary artery disease. | Journal of interventional cardiology 20041201 |
| New approaches to ostial and bifurcation lesions. | Journal of interventional cardiology 20041201 |
| Vascular brachytherapy versus sirolimus eluting stents for the treatment of in-stent restenosis: a prospective registry. | Heart (British Cardiac Society) 20041201 |
| Random mutagenesis of an essential Candida albicans gene. | Current genetics 20041201 |
| New bifurcation stenting technique: shunt stenting. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20041201 |
| Recovery of chronic renal impairment with sirolimus after lung transplantation. | The Annals of thoracic surgery 20041201 |
| Rapamycin inhibits doxorubicin-induced NF-kappaB/Rel nuclear activity and enhances the apoptosis of melanoma cells. | European journal of cancer (Oxford, England : 1990) 20041201 |
| Sirolimus with neoral versus mycophenolate mofetil with neoral is associated with decreased renal allograft survival. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201 |
| Therapeutic drug monitoring for everolimus in heart transplant recipients based on exposure-effect modeling. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041201 |
| Mammalian target of rapamycin (mTOR) inhibitors as anti-cancer agents. | Current cancer drug targets 20041201 |
| The complexity of PTEN: mutation, marker and potential target for therapeutic intervention. | Expert opinion on therapeutic targets 20041201 |
| Therapeutic potential of target of rapamycin inhibitors. | Expert opinion on therapeutic targets 20041201 |
| Inhibition of mTOR activity restores tamoxifen response in breast cancer cells with aberrant Akt Activity. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041201 |
| Treatment of coronary artery disease in dialysis patients with sirolimus-eluting stents: 1-year clinical follow-up of a consecutive series of cases. | The Journal of invasive cardiology 20041201 |
| Sirolimus-eluting stents for percutaneous coronary intervention in acute myocardial infarction Lesson from a case-controlled comparison of bare metal versus drug-eluting stents in thrombus-laden lesions. | Zeitschrift fur Kardiologie 20041201 |
| Cap-independent protein translation is initially responsible for 4-(N-methylnitrosamino)-1-(3-pyridyl)-butanone (NNK)-induced apoptosis in normal human bronchial epithelial cells. | Journal of veterinary science 20041201 |
| Pharmacokinetics of immunosuppressants: a perspective on ethnic differences. | International journal of clinical pharmacology and therapeutics 20041201 |
| [16th EORTC-NCI-AACR symposium on new molecular targets and cancer therapeutics]. | Bulletin du cancer 20041201 |
| Akt up-regulation increases resistance to microtubule-directed chemotherapeutic agents through mammalian target of rapamycin. | Molecular cancer therapeutics 20041201 |
| [Percutaneous coronary angioplasty in diabetic patients: new prospects with drug-eluting stents]. | Revue medicale de Liege 20041201 |
| Regulated expression of galectin-1 during T-cell activation involves Lck and Fyn kinases and signaling through MEK1/ERK, p38 MAP kinase and p70S6 kinase. | Molecular and cellular biochemistry 20041201 |
| Initial experience with sirolimus and mycophenolate mofetil for renal rescue from cyclosporine nephrotoxicity after heart transplantation. | Transplantation proceedings 20041201 |
| The relative proportions of sirolimus metabolites in blood using HPLC with mass-spectrometric detection. | Transplantation proceedings 20041201 |
| Clinical relevance of sirolimus drug interactions in transplant patients. | Transplantation proceedings 20041201 |
| Sirolimus upregulates aP2 expression in human monocytes and macrophages. | Transplantation proceedings 20041201 |
| Absence of teratogenicity of sirolimus used during early pregnancy in a liver transplant recipient. | Transplantation proceedings 20041201 |
| What reimbursement for coronary revascularization with drug-eluting stents? | The European journal of health economics : HEPAC : health economics in prevention and care 20041201 |
| Exposure-response relationships and drug interactions of sirolimus. | The AAPS journal 20041201 |
| Mycobacterium xenopi pulmonary infection in two renal transplant recipients under sirolimus therapy. | Transplant infectious disease : an official journal of the Transplantation Society 20041201 |
| Mammalian target of rapamycin. | Seminars in oncology 20041201 |
| Mutagenic and cytotoxic effects of immunosuppressive drugs on human lymphocyte cultures. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20041201 |
| Nonuniform strut distribution correlates with more neointimal hyperplasia after sirolimus-eluting stent implantation. | Circulation 20041130 |
| Everolimus (Certican) 12-month safety and efficacy versus mycophenolate mofetil in de novo renal transplant recipients. | Transplantation 20041127 |
| Sirolimus may not cause neurotoxicity in kidney and liver transplant recipients. | Neurology 20041123 |
| Memory-like alterations in Aplysia axons after nerve injury or localized depolarization. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041117 |
| Comparison of late luminal loss response pattern after sirolimus-eluting stent implantation or conventional stenting. | Circulation 20041116 |
| Comparison of clinical and angiographic outcome of sirolimus-eluting stent implantation versus cutting balloon angioplasty for coronary in-stent restenosis. | The American journal of cardiology 20041115 |
| Targeted T-cell depletion or CD154 blockade generates mixed hemopoietic chimerism and donor-specific tolerance in mice treated with sirolimus and donor bone marrow. | Transplantation 20041115 |
| Early cyclosporine a withdrawal in kidney-transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions. | Transplantation 20041115 |
| Everolimus and reduced-exposure cyclosporine in de novo renal-transplant recipients: a three-year phase II, randomized, multicenter, open-label study. | Transplantation 20041115 |
| Investigation of pediatric renal transplant recipients with heavy proteinuria after sirolimus rescue. | Transplantation 20041115 |
| Construction of a cyclin D1-Cdk2 fusion protein to model the biological functions of cyclin D1-Cdk2 complexes. | The Journal of biological chemistry 20041112 |
| Autocrine transforming growth factor alpha regulates cell adhesion by multiple signaling via specific phosphorylation sites of p70S6 kinase in colon cancer cells. | The Journal of biological chemistry 20041105 |
| Tor signaling and nutrient-based signals converge on Mks1p phosphorylation to regulate expression of Rtg1.Rtg3p-dependent target genes. | The Journal of biological chemistry 20041105 |
| Brain-derived neurotrophic factor induces mammalian target of rapamycin-dependent local activation of translation machinery and protein synthesis in neuronal dendrites. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20041103 |
| Phase I/pharmacokinetic study of CCI-779 in patients with recurrent malignant glioma on enzyme-inducing antiepileptic drugs. | Investigational new drugs 20041101 |
| The mTOR signaling pathway mediates control of ribosomal protein mRNA translation in rat liver. | The international journal of biochemistry & cell biology 20041101 |
| Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. | Nature cell biology 20041101 |
| Cyclooxygenase-2 expression in experimental post-transplant obliterative bronchiolitis. | The Journal of pathology 20041101 |
| De novo kidney transplantation without use of calcineurin inhibitors preserves renal structure and function at two years. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041101 |
| Predictors of success in conversion from calcineurin inhibitor to sirolimus in chronic allograft dysfunction. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041101 |
| Initiation of mRNA translation in oncogenesis: the role of eIF4E. | Cell cycle (Georgetown, Tex.) 20041101 |
| Targeting metastatic leiomyosarcoma by rapamycin plus gemcitabine: an intriguing clinical observation. | International journal of molecular medicine 20041101 |
| Sirolimus and angiotensin-converting enzyme inhibitors together induce tongue oedema in renal transplant recipients. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041101 |
| Sirolimus-induced pneumonitis, sinusitis and macular oedema. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041101 |
| Sirolimus- or paclitaxel-eluting stents to prevent coronary artery restenosis. | Expert opinion on pharmacotherapy 20041101 |
| Vascular restenosis - striving for therapy. | Expert opinion on pharmacotherapy 20041101 |
| Drug-eluting stents have made brachytherapy obsolete. | Current opinion in cardiology 20041101 |
| Selectin inhibitor bimosiamose prolongs survival of kidney allografts by reduction in intragraft production of cytokines and chemokines. | Journal of the American Society of Nephrology : JASN 20041101 |
| regulation of peroxisome proliferator-activated receptor-gamma activity by mammalian target of rapamycin and amino acids in adipogenesis. | Diabetes 20041101 |
| Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma. | Apoptosis : an international journal on programmed cell death 20041101 |
| Sirolimus-eluting stents for the prevention of restenosis in a worst-case scenario of diffuse and recurrent in-stent restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20041101 |
| Drug-eluting stents for secondary prevention of restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20041101 |
| Hybrid coronary revascularization in the era of drug-eluting stents. | The Annals of thoracic surgery 20041101 |
| Rapamycin-eluting stents for the treatment of bifurcated coronary lesions: a randomized comparison of a simple versus complex strategy. | American heart journal 20041101 |
| Drug-eluting stents: a mechanical and pharmacologic approach to coronary artery disease. | Pharmacotherapy 20041101 |
| Everolimus suppresses cancellous bone loss, bone resorption, and cathepsin K expression by osteoclasts. | Bone 20041101 |
| Combining targeted agents in lung cancer. | Clinical lung cancer 20041101 |
| [Consensus-recommendations for sirolimus in liver transplantation]. | Zeitschrift fur Gastroenterologie 20041101 |
| Sirolimus addition is beneficial for renal allograft dysfunction due to simultaneous acute rejection episode and calcineurin inhibitor nephrotoxicity. | Transplantation proceedings 20041101 |
| Combined use of sirolimus and voriconazole in renal transplantation: a report of two cases. | Transplantation proceedings 20041101 |
| Targeting the molecular target of rapamycin (mTOR). | Current opinion in oncology 20041101 |
| Bibliography. Current world literature. Therapeutic modalities. | Current opinion in oncology 20041101 |
| Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress. | The Journal of biological chemistry 20041029 |
| Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling. | The Journal of biological chemistry 20041029 |
| Immunomodulatory effects of combination of pooled human gammaglobulin and rapamycin on cell proliferation and apoptosis in the mixed lymphocyte reaction. | Transplantation 20041027 |
| Sirolimus in de novo heart transplant recipients reduces acute rejection and prevents coronary artery disease at 2 years: a randomized clinical trial. | Circulation 20041026 |
| Targeting the mammalian target of rapamycin (mTOR): a new approach to treating cancer. | British journal of cancer 20041018 |
| Rapamycin causes activation of protein phosphatase-2A1 and nuclear translocation of PCNA in CD4+ T cells. | Biochemical and biophysical research communications 20041015 |
| Rapamycin inhibits proliferation and differentiation of human endothelial progenitor cells in vitro. | Experimental cell research 20041015 |
| Bivalirudin versus heparin as an antithrombotic agent in patients treated with a sirolimus-eluting stent. | The American journal of cardiology 20041015 |
| BK virus-associated nephropathy in renal allograft recipients: rescue therapy by sirolimus-based immunosuppression. | Transplantation 20041015 |
| Putting the rap on Akt. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20041015 |
| Activation of the Akt/mammalian target of rapamycin/4E-BP1 pathway by ErbB2 overexpression predicts tumor progression in breast cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041015 |
| Effect of rapamycin alone and in combination with antiangiogenesis therapy in an orthotopic model of human pancreatic cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041015 |
| Targeting mammalian target of rapamycin synergistically enhances chemotherapy-induced cytotoxicity in breast cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041015 |
| Problems with drug-eluting coronary stents--the FDA perspective. | The New England journal of medicine 20041014 |
| Receptor activity-independent recruitment of betaarrestin2 reveals specific signalling modes. | The EMBO journal 20041013 |
| In rat hepatocytes glucagon increases mammalian target of rapamycin phosphorylation on serine 2448 but antagonizes the phosphorylation of its downstream targets induced by insulin and amino acids. | The Journal of biological chemistry 20041008 |
| Oral rapamycin to inhibit restenosis after stenting of de novo coronary lesions: the Oral Rapamune to Inhibit Restenosis (ORBIT) study. | Journal of the American College of Cardiology 20041006 |
| Evaluation of a cyano stationary phase for the determination of tacrolimus, sirolimus and cyclosporin A in whole blood by high-performance liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041005 |
| Activation of an autoregulated protein kinase by conditional protein splicing. | Angewandte Chemie (International ed. in English) 20041004 |
| Directing flux in glycan biosynthetic pathways with a small molecule switch. | Chembiochem : a European journal of chemical biology 20041004 |
| Human placental taurine transporter in uncomplicated and IUGR pregnancies: cellular localization, protein expression, and regulation. | American journal of physiology. Regulatory, integrative and comparative physiology 20041001 |
| Simple extraction protocol for analysis of immunosuppressant drugs in whole blood. | Clinical chemistry 20041001 |
| Tolerability and steady-state pharmacokinetics of everolimus in maintenance renal transplant patients. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041001 |
| Sirolimus-associated hepatotoxicity in liver transplantation. | The Annals of pharmacotherapy 20041001 |
| Alterations in glucose metabolism by cyclosporine in rat brain slices link to oxidative stress: interactions with mTOR inhibitors. | British journal of pharmacology 20041001 |
| Effect of sirolimus withdrawal in patients with deteriorating renal function. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20041001 |
| What is the calcineurin inhibitor of choice for pediatric renal transplantation? | Pediatric transplantation 20041001 |
| Current immunosuppressive agents in pediatric renal transplantation: efficacy, side-effects and utilization. | Pediatric transplantation 20041001 |
| Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway. | Annals of oncology : official journal of the European Society for Medical Oncology 20041001 |
| Echolucent neointimal hyperplasia 'dark wall' after sirolimus eluting stent implantation. | Heart (British Cardiac Society) 20041001 |
| Routine sirolimus eluting stent implantation for unselected in-stent restenosis: insights from the rapamycin eluting stent evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry. | Heart (British Cardiac Society) 20041001 |
| Mammalian target of rapamycin and 3-phosphatidylinositol 3-kinase pathway inhibition enhances growth inhibition of transforming growth factor-beta1 in prostate cancer cells. | The Journal of urology 20041001 |
| Sirolimus-based immunosuppression for liver transplantation in the presence of extended criteria for hepatocellular carcinoma. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20041001 |
| Hepatocellular cancer, transplantation, and sirolimus. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20041001 |
| [Sirolimus-eluting stents for the treatment of symptomatic extracranial vertebral artery stenoses: early experience and 6-month follow-up]. | RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin 20041001 |
| New insights into drug absorption: studies with sirolimus. | Therapeutic drug monitoring 20041001 |
| Everolimus therapeutic concentration range defined from a prospective trial with reduced-exposure cyclosporine in de novo kidney transplantation. | Therapeutic drug monitoring 20041001 |
| Raptor protein contains a caspase-like domain. | Trends in biochemical sciences 20041001 |
| Human cytomegalovirus infection induces rapamycin-insensitive phosphorylation of downstream effectors of mTOR kinase. | Journal of virology 20041001 |
| Effectiveness of sirolimus-eluting stent implantation for the treatment of coronary artery disease in octogenarians. | The American journal of cardiology 20041001 |
| Comparison of acute and long-term results and underlying mechanisms from sirolimus-eluting stent implantation for the treatment of in-stent restenosis and recurrent in-stent restenosis in patients in whom intracoronary radiation failed as assessed by intravascular ultrasound. | The American journal of cardiology 20041001 |
| Ischemia-reperfusion induces glomerular and tubular activation of proinflammatory and antiapoptotic pathways: differential modulation by rapamycin. | Journal of the American Society of Nephrology : JASN 20041001 |
| PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p. | Eukaryotic cell 20041001 |
| Pharmacokinetics of rapamycin-eluting stents in miniswine coronary model. | Chinese medical journal 20041001 |
| Drug-eluting stents: some bare facts. | Lancet (London, England) 20041001 |
| Late thrombosis in drug-eluting coronary stents after discontinuation of antiplatelet therapy. | Lancet (London, England) 20041001 |
| Drug-eluting stents: from randomized trials to the real world. | Minerva cardioangiologica 20041001 |
| Coronary bifurcation stenting. Current techniques, outcome and possible future developments. | Minerva cardioangiologica 20041001 |
| Saphenous vein graft disease. | Minerva cardioangiologica 20041001 |
| Drug-eluting stents: the beginning of the end of restenosis? | Cleveland Clinic journal of medicine 20041001 |
| [Drug eluting stents--end of restenosis?]. | Vnitrni lekarstvi 20041001 |
| [Immunossupresive drugs in renal transplantation]. | Polskie Archiwum Medycyny Wewnetrznej 20041001 |
| Medical devices; clinical chemistry and clinical toxicology devices; classification of sirolimus test system devices. Final rule. | Federal register 20040930 |
| Akt-1 expression level regulates CNS precursors. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040929 |
| Active role of chimerism in transplantation tolerance induced by antilymphocyte serum, sirolimus, and bone-marrow-cell infusion. | Transplantation 20040927 |
| The selective use of basiliximab versus thymoglobulin in combination with sirolimus for cadaveric renal transplant recipients at low risk versus high risk for delayed graft function. | Transplantation 20040927 |
| Correlation between human leukocyte antigen antibody production and serum creatinine in patients receiving sirolimus monotherapy after Campath-1H induction. | Transplantation 20040927 |
| Sirolimus-induced interstitial pneumonitis after renal transplantation. | Transplantation 20040927 |
| Mammalian target of rapamycin inhibition as therapy for hematologic malignancies. | Cancer 20040915 |
| Late coronary thrombosis secondary to a sirolimus-eluting stent. | Circulation 20040914 |
| Uth1p is involved in the autophagic degradation of mitochondria. | The Journal of biological chemistry 20040910 |
| Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation. | Experimental cell research 20040910 |
| NPR1 kinase and RSP5-BUL1/2 ubiquitin ligase control GLN3-dependent transcription in Saccharomyces cerevisiae. | The Journal of biological chemistry 20040903 |
| Regulation of adipocyte differentiation and insulin action with rapamycin. | Biochemical and biophysical research communications 20040903 |
| Both mitogen-activated protein kinase and phosphatidylinositol 3-kinase signalling are required in epidermal growth factor-induced human trophoblast migration. | Molecular human reproduction 20040901 |
| Sirolimus for GVHD prophylaxis in allogeneic stem cell transplantation. | Bone marrow transplantation 20040901 |
| Trace analysis of rapamycin in human blood by micellar electrokinetic chromatography. | Analytical and bioanalytical chemistry 20040901 |
| The Cypher stent: no longer efficacious at three months in the porcine model? | Cardiovascular research 20040901 |
| Long-term effects of polymer-based, slow-release, sirolimus-eluting stents in a porcine coronary model. | Cardiovascular research 20040901 |
| CYP3A4 and P-glycoprotein activity in healthy controls and transplant patients on cyclosporin vs. tacrolimus vs. sirolimus. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040901 |
| Sirolimus-induced leukocytoclastic vasculitis: the second case reported. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040901 |
| The use of drug eluting stents in single and multivessel disease: results from a single centre experience. | Heart (British Cardiac Society) 20040901 |
| Sirolimus eluting stent implantation for patients with multivessel disease: rationale for the Arterial Revascularisation Therapies Study part II (ARTS II). | Heart (British Cardiac Society) 20040901 |
| Prevention of restenosis after coronary angioplasty. | Current opinion in cardiology 20040901 |
| ANG II activates effectors of mTOR via PI3-K signaling in human coronary smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20040901 |
| Synovial fibroblasts from patients with rheumatoid arthritis, like fibroblasts from Graves' disease, express high levels of IL-16 when treated with Igs against insulin-like growth factor-1 receptor. | Journal of immunology (Baltimore, Md. : 1950) 20040901 |
| Preservation of graft function in low-risk living kidney transplant recipients treated with a combination of sirolimus and cyclosporine. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20040901 |
| Clinical and angiographic outcome after sirolimus-eluting stent implantation in aorto-ostial lesions. | Journal of the American College of Cardiology 20040901 |
| Type D personality predicts death or myocardial infarction after bare metal stent or sirolimus-eluting stent implantation: a Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEARCH) registry substudy. | Journal of the American College of Cardiology 20040901 |
| Effect of sirolimus on renal ischaemia/reperfusion injury in normotensive and hypertensive rats. | Transplant international : official journal of the European Society for Organ Transplantation 20040901 |
| Role of siroliumus, a novel immunosuppressive drug in heart and lung transplantation. | Respiratory medicine 20040901 |
| 5-HT stimulates eEF2 dephosphorylation in a rapamycin-sensitive manner in Aplysia neurites. | Journal of neurochemistry 20040901 |
| Elective sirolimus-eluting stent implantation for multivessel disease involving significant LAD stenosis: one-year clinical outcomes of 99 consecutive patients--the Rotterdam experience. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040901 |
| Single-digit target vessel revascularization in multivessel coronary interventions with sirolimus-eluting stents: goodbye to coronary bypass grafting. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040901 |
| Bifurcation disease: optimal angiographic result yet suboptimal long-term outcome. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040901 |
| Drug-eluting stents: caution and concerns for long-term outcome. | Coronary artery disease 20040901 |
| Rapamycin-sensitive induction of eukaryotic initiation factor 4F in regenerating mouse liver. | Hepatology (Baltimore, Md.) 20040901 |
| Prolyl isomerases in yeast. | Frontiers in bioscience : a journal and virtual library 20040901 |
| Difficulty in establishing sirolimus therapy as a cause of interstitial pneumonitis in renal-transplant recipients. | Journal of the Formosan Medical Association = Taiwan yi zhi 20040901 |
| [Drug-coated stents. Where do we stand in 2004?]. | Zeitschrift fur Kardiologie 20040901 |
| [When are drug-eluting stents effective? A critical analysis of the presently available data]. | Zeitschrift fur Kardiologie 20040901 |
| Drug-eluting stents: is it the beginning of the end for coronary artery bypass surgery? | Chinese medical journal 20040901 |
| Rapamycin-eluting stents for the treatment of unprotected left main coronary disease. | American heart journal 20040901 |
| Current and future immunosuppressive strategies in renal transplantation. | Pharmacotherapy 20040901 |
| Sirolimus (rapamycin) reduces the incidence of acute rejection episodes in renal transplantation: an initial experience in Taiwan. | Transplantation proceedings 20040901 |
| Sirolimus in chronic allograft nephropathy. | Transplantation proceedings 20040901 |
| Is sirolimus a safe alternative to reduce or eliminate calcineurin inhibitors in chronic allograft nephropathy in kidney transplantation? | Transplantation proceedings 20040901 |
| Pharmacokinetic variability of sirolimus in Taiwanese renal transplant recipients. | Transplantation proceedings 20040901 |
| Inhibition of mammalian target of rapamycin activates apoptosis signal-regulating kinase 1 signaling by suppressing protein phosphatase 5 activity. | The Journal of biological chemistry 20040827 |
| Long-term outcome of sirolimus rescue in kidney-pancreas transplantation. | Transplantation 20040827 |
| Glucose-potentiated chemotaxis in human vascular smooth muscle is dependent on cross-talk between the PI3K and MAPK signaling pathways. | Circulation research 20040820 |
| [PTCA with drug eluting stent. 90% fewer restenoses in high risk patients]. | MMW Fortschritte der Medizin 20040819 |
| Randomized, double-blind, placebo-controlled trial of oral sirolimus for restenosis prevention in patients with in-stent restenosis: the Oral Sirolimus to Inhibit Recurrent In-stent Stenosis (OSIRIS) trial. | Circulation 20040817 |
| Rapid simultaneous quantification of immunosuppressants in transplant patients by turbulent flow chromatography combined with tandem mass spectrometry. | Clinica chimica acta; international journal of clinical chemistry 20040816 |
| Ras, PI3-kinase and mTOR signaling in cardiac hypertrophy. | Cardiovascular research 20040815 |
| Acute nephrotoxicity of tacrolimus and sirolimus in renal isografts: differential intragraft expression of transforming growth factor-beta1 and alpha-smooth muscle actin. | Transplantation 20040815 |
| Differential effects of everolimus and cyclosporine A on intimal alpha-actin-positive cell dynamics of carotid allografts in mice. | Transplantation 20040815 |
| Comparison of outcomes after delayed graft function: sirolimus-based versus other calcineurin-inhibitor sparing induction immunosuppression regimens. | Transplantation 20040815 |
| [Immunosuppression with sirolimus so donor kidneys survive longer]. | MMW Fortschritte der Medizin 20040805 |
| Cost-effectiveness of sirolimus-eluting stents for treatment of complex coronary stenoses: results from the Sirolimus-Eluting Balloon Expandable Stent in the Treatment of Patients With De Novo Native Coronary Artery Lesions (SIRIUS) trial. | Circulation 20040803 |
| Economics of sirolimus-eluting stents: drug-eluting stents have really arrived. | Circulation 20040803 |
| Marked malapposition and aneurysm formation after sirolimus-eluting coronary stent implantation. | Circulation 20040803 |
| G1 cell cycle progression and the expression of G1 cyclins are regulated by PI3K/AKT/mTOR/p70S6K1 signaling in human ovarian cancer cells. | American journal of physiology. Cell physiology 20040801 |
| Two-year incidence of malignancy in sirolimus-treated renal transplant recipients: results from five multicenter studies. | Clinical transplantation 20040801 |
| Cross-talk between the survival kinases during early reperfusion: its contribution to ischemic preconditioning. | Cardiovascular research 20040801 |
| Late incomplete lesion coverage following Cypher stent deployment for diffuse right coronary artery stenosis. | Heart (British Cardiac Society) 20040801 |
| Using established immunosuppressant therapy effectively: lessons from the measurement of mycophenolic acid plasma concentrations. | Therapeutic drug monitoring 20040801 |
| Improvement in renal function and rejection control in pediatric liver transplant recipients with the introduction of sirolimus. | Pediatric transplantation 20040801 |
| Pilot randomized study of early tacrolimus withdrawal from a regimen with sirolimus plus tacrolimus in kidney transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040801 |
| Therapeutic drug monitoring of sirolimus: effect of concomitant immunosuppressive therapy and optimization of drug dosing. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040801 |
| Effectiveness of sirolimus-eluting stent implantation for treatment of in-stent restenosis after brachytherapy failure. | The American journal of cardiology 20040801 |
| The current status of stent placement in small coronary arteries < 3.0 mm in diameter. | The Journal of invasive cardiology 20040801 |
| Contemporary treatment of small-vessel disease. | The Journal of invasive cardiology 20040801 |
| Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells. | British journal of haematology 20040801 |
| Programmed autophagy in the Drosophila fat body is induced by ecdysone through regulation of the PI3K pathway. | Developmental cell 20040801 |
| Rapamycin suppresses experimental aortic aneurysm growth. | Journal of vascular surgery 20040801 |
| Aortic eNOS expression and phosphorylation in Apo-E knockout mice: differing effects of rapamycin and simvastatin. | Surgery 20040801 |
| Oral rapamycin to prevent human coronary stent restenosis: a pilot study. | American heart journal 20040801 |
| Are drug-eluting stents a panacea for patients with coronary heart disease? | Lancet (London, England) 20040801 |
| A hierarchical Bayesian meta-analysis of randomised clinical trials of drug-eluting stents. | Lancet (London, England) 20040801 |
| Activation of AMP-activated protein kinase inhibits protein synthesis associated with hypertrophy in the cardiac myocyte. | The Journal of biological chemistry 20040730 |
| Bcl-2 phosphorylation and apoptosis activated by damaged microtubules require mTOR and are regulated by Akt. | Oncogene 20040729 |
| AKT and mTOR phosphorylation is frequently detected in ovarian cancer and can be targeted to disrupt ovarian tumor cell growth. | Oncogene 20040729 |
| Treatment of left anterior descending coronary artery disease with sirolimus-eluting stents. | Circulation 20040727 |
| Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. | Current biology : CB 20040727 |
| A retrospective review of liver transplant patients treated with sirolimus from a single center: an analysis of sirolimus-related complications. | Transplantation 20040727 |
| Everolimus-induced drug fever after heart transplantation. | Transplantation 20040727 |
| Evidence for cyclin D3 as a novel target of rapamycin in human T lymphocytes. | The Journal of biological chemistry 20040723 |
| In vitro study of release mechanisms of paclitaxel and rapamycin from drug-incorporated biodegradable stent matrices. | Journal of controlled release : official journal of the Controlled Release Society 20040723 |
| An activated mTOR mutant supports growth factor-independent, nutrient-dependent cell survival. | Oncogene 20040722 |
| Regulation of B-Raf kinase activity by tuberin and Rheb is mammalian target of rapamycin (mTOR)-independent. | The Journal of biological chemistry 20040716 |
| Aldosterone rapidly activates Src kinase in M-1 cells involving the mineralocorticoid receptor and HSP84. | FEBS letters 20040716 |
| Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20040714 |
| Images in cardiovascular medicine. Vascular healing 4 years after the implantation of sirolimus-eluting stent in humans: a histopathological examination. | Circulation 20040706 |
| Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus. | The Journal of biological chemistry 20040702 |
| Association of rapamycin and co-stimulation blockade using anti-B7 antibodies in renal allotransplantation in baboons. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040701 |
| Reversing drug resistance in vivo. | Cell cycle (Georgetown, Tex.) 20040701 |
| Biological aspects of radiation and drug-eluting stents for the prevention of restenosis. | Cardiovascular research 20040701 |
| Sirolimus impairs gonadal function in heart transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040701 |
| Successful simultaneous islet-kidney transplantation using a steroid-free immunosuppression: two-year follow-up. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040701 |
| Different costimulatory and growth factor requirements for CD4+ and CD8+ T cell-mediated rejection. | Journal of immunology (Baltimore, Md. : 1950) 20040701 |
| Differential expression of chemokines and chemokine receptors in murine islet allografts: the role of CCR2 and CCR5 signaling pathways. | Journal of the American Society of Nephrology : JASN 20040701 |
| Effectiveness of sirolimus-Eluting stent implantation for coronary narrowings <50% in diameter. | The American journal of cardiology 20040701 |
| Restenosis rates following bifurcation stenting with sirolimus-eluting stents for de novo narrowings. | The American journal of cardiology 20040701 |
| Drug-eluting stents: the panacea for restenosis? | Singapore medical journal 20040701 |
| A stent is not just a stent: Stent construction and design do matter in its clinical performance. | Singapore medical journal 20040701 |
| Clinical outcomes for sirolimus-eluting stent implantation and vascular brachytherapy for the treatment of in-stent restenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701 |
| 'At least but not at last' equivalent! | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701 |
| Vascular brachytherapy vs. drug-eluting stents for the treatment of in-stent restenosis: the jury's still out. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701 |
| Elective sirolimus-eluting stent implantation for left main coronary artery disease: six-month angiographic follow-up and 1-year clinical outcome. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040701 |
| Immunosuppression and modulation in liver transplantation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040701 |
| Rapamycin and chronic lung rejection. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040701 |
| [Antiproliferative drug-eluting stents: systematic review of the benefits and estimate of economic impact]. | Revista espanola de cardiologia 20040701 |
| Drug-eluting stents: the end of restenosis? | Annals of the Academy of Medicine, Singapore 20040701 |
| [Inhibition of hypoxia-inducible factor 1alpha expression and tumor growth in SKOV3 ovarian cancer model by sirolimus]. | Zhonghua fu chan ke za zhi 20040701 |
| The mTOR/p70S6K signal transduction pathway plays a role in cardiac hypertrophy and influences expression of myosin heavy chain genes in vivo. | Cardiovascular drugs and therapy 20040701 |
| Isolation, structure determination and biological activity of 15-deoxo-7,32-O-didesmethylrapamycin from the soil actinomycete LL-D45042. | The Journal of antibiotics 20040701 |
| Pro- and anti-cancer effects of immunosuppressive agents used in organ transplantation. | Transplantation 20040627 |
| Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload. | Circulation 20040622 |
| Regulation of translation elongation and phosphorylation of eEF2 in rat pancreatic acini. | Biochemical and biophysical research communications 20040618 |
| Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism. | The Biochemical journal 20040615 |
| New target, new drug, old paradigm. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040615 |
| Safety and pharmacokinetics of escalated doses of weekly intravenous infusion of CCI-779, a novel mTOR inhibitor, in patients with cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040615 |
| Angiographic and volumetric intravascular ultrasound comparison between direct sirolimus-eluting stent implantation versus predilation. | The American journal of cardiology 20040615 |
| Stable expression of small interfering RNA sensitizes TEL-PDGFbetaR to inhibition with imatinib or rapamycin. | The Journal of clinical investigation 20040615 |
| New immunosuppressant class not without serious concerns. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040615 |
| Intraprocedural stent thrombosis during implantation of sirolimus-eluting stents. | Circulation 20040608 |
| 96-Well liquid-liquid extraction liquid chromatography-tandem mass spectrometry method for the quantitative determination of ABT-578 in human blood samples. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040605 |
| Interferon alpha-induced apoptosis in tumor cells is mediated through the phosphoinositide 3-kinase/mammalian target of rapamycin signaling pathway. | The Journal of biological chemistry 20040604 |
| Degradation of PKB/Akt protein by inhibition of the VEGF receptor/mTOR pathway in endothelial cells. | Oncogene 20040603 |
| Significant reduction in restenosis after the use of sirolimus-eluting stents in the treatment of chronic total occlusions. | Journal of the American College of Cardiology 20040602 |
| Impact of final stent dimensions on long-term results following sirolimus-eluting stent implantation: serial intravascular ultrasound analysis from the sirius trial. | Journal of the American College of Cardiology 20040602 |
| Rab7 is required for the normal progression of the autophagic pathway in mammalian cells. | Journal of cell science 20040601 |
| Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease. | Nature genetics 20040601 |
| Increased risk of thrombotic microangiopathy in patients receiving a cyclosporin-sirolimus combination. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601 |
| Sirolimus-based therapy following early cyclosporine withdrawal provides significantly improved renal histology and function at 3 years. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601 |
| Outcome at 3 years with a prednisone-free maintenance regimen: a single-center experience with 349 kidney transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601 |
| Sirolimus-induced angioedema. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040601 |
| Post-sirolimus-eluting stent restenosis treated with repeat percutaneous intervention: late angiographic and clinical outcomes. | Circulation 20040601 |
| mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways. | Nature medicine 20040601 |
| HIV infection of primary human T cells is determined by tunable thresholds of T cell activation. | European journal of immunology 20040601 |
| Sirolimus- versus paclitaxel-eluting stents in patients with stenosis in a native coronary artery. | Expert opinion on pharmacotherapy 20040601 |
| Creatine kinase-myocardial band isoenzyme elevation after percutaneous coronary interventions using sirolimus-eluting stents. | The American journal of cardiology 20040601 |
| TORward AKTually useful mouse models. | Nature medicine 20040601 |
| Sirolimus for pediatric liver transplant recipients with post-transplant lymphoproliferative disease and hepatoblastoma. | Pediatric transplantation 20040601 |
| Immunosuppressive drug monitoring of sirolimus and cyclosporine in pediatric patients. | Clinical biochemistry 20040601 |
| First experience with rapamycin-based immunosuppression to improve kidney function after heart transplantation. | The Thoracic and cardiovascular surgeon 20040601 |
| The impact of Sirolimus Eluting stents in interventional cardiology. | International journal of cardiology 20040601 |
| Procedural and long-term results of sirolimus-eluting stent in patients at high risk for restenosis. | Minerva cardioangiologica 20040601 |
| Pharmacokinetics of sirolimus in heart transplant recipients with chronic renal impairment. | Transplantation proceedings 20040601 |
| Chronic allograft nephropathy: pathogenesis and management of an important posttransplant complication. | Progress in transplantation (Aliso Viejo, Calif.) 20040601 |
| Future immunosuppressive agents in solid-organ transplantation. | Progress in transplantation (Aliso Viejo, Calif.) 20040601 |
| Strategies to prevent chronic allograft nephropathy in kidney transplantation: focus on calcineurin inhibitors. | Progress in transplantation (Aliso Viejo, Calif.) 20040601 |
| The efficacy and limitations of sirolimus conversion in liver transplant patients who develop renal dysfunction on calcineurin inhibitors. | Digestive diseases and sciences 20040601 |
| Eluting stents: an effective, promising solution? | Italian heart journal : official journal of the Italian Federation of Cardiology 20040601 |
| Sirolimus and mycophenolate mofetil as calcineurin inhibitor-free immunosuppression in a cardiac transplant patient with chronic renal failure. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040601 |
| Fatal interstitial pneumonitis associated with sirolimus therapy in a heart transplant recipient. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040601 |
| [Involvement of hnRNP in selective translation inhibition of mRNA by rapamycin]. | The Japanese journal of antibiotics 20040601 |
| [Effect of EM201, an in vivo metabolite of erythromycin (EM), on signal transduction of IL-2 receptor]. | The Japanese journal of antibiotics 20040601 |
| Dimerization is required for activation of eIF2 kinase Gcn2 in response to diverse environmental stress conditions. | The Journal of biological chemistry 20040528 |
| Mammalian target of rapamycin positively regulates collagen type I production via a phosphatidylinositol 3-kinase-independent pathway. | The Journal of biological chemistry 20040528 |
| Metabolic interaction between cyclosporine and sirolimus. | Transplantation 20040527 |
| Wound-healing complications after kidney transplantation: a prospective, randomized comparison of sirolimus and tacrolimus. | Transplantation 20040527 |
| Impact of sirolimus-eluting stents on outcome in diabetic patients: a SIRIUS (SIRolImUS-coated Bx Velocity balloon-expandable stent in the treatment of patients with de novo coronary artery lesions) substudy. | Circulation 20040518 |
| Incidence of thrombotic stent occlusion during the first three months after sirolimus-eluting stent implantation in 500 consecutive patients. | The American journal of cardiology 20040515 |
| Perturbed IFN-gamma-Jak-signal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-gamma treatment. | Cancer research 20040515 |
| Rapamycin protects allografts from rejection while simultaneously attacking tumors in immunosuppressed mice. | Transplantation 20040515 |
| An update on clinical outcomes in heart and lung transplantation. | Transplantation 20040515 |
| Involvement of integrins and Src in insulin signaling toward autophagic proteolysis in rat liver. | The Journal of biological chemistry 20040514 |
| Critical role of T-loop and H-motif phosphorylation in the regulation of S6 kinase 1 by the tuberous sclerosis complex. | The Journal of biological chemistry 20040514 |
| Essential role of PDGFRalpha-p70S6K signaling in mesenchymal cells during therapeutic and tumor angiogenesis in vivo: role of PDGFRalpha during angiogenesis. | Circulation research 20040514 |
| 'Me-too' products--friend or foe? | The New England journal of medicine 20040513 |
| Six- and twelve-month results from first human experience using everolimus-eluting stents with bioabsorbable polymer. | Circulation 20040511 |
| How many grails do we need? | Circulation 20040511 |
| Everolimus stent proves effective. | Circulation 20040511 |
| Dual regulation of MMP-2 expression by the type 1 insulin-like growth factor receptor: the phosphatidylinositol 3-kinase/Akt and Raf/ERK pathways transmit opposing signals. | The Journal of biological chemistry 20040507 |
| Images in cardiovascular medicine. Coronary uptake of gallium-67 citrate after implantation of sirolimus-eluting stent. | Circulation 20040504 |
| Isolation and characterization of pre-rapamycin, the first macrocyclic intermediate in the biosynthesis of the immunosuppressant rapamycin by S. hygroscopicus. | Angewandte Chemie (International ed. in English) 20040503 |
| Early experiences and clinical implications of restenosis and drug-eluting stents: Part 2. | The Annals of pharmacotherapy 20040501 |
| Pharmacokinetics of sirolimus and tacrolimus in pediatric transplant patients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040501 |
| Sirolimus eluting stent aborted recurrent distal left main in-stent restenosis involving bifurcation. | Heart (British Cardiac Society) 20040501 |
| Optimizing the immunosuppressive regimen in heart transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040501 |
| Effectiveness of the sirolimus-eluting stent in the treatment of patients with a prior history of coronary artery bypass graft surgery. | Coronary artery disease 20040501 |
| Acute rapamycin nephrotoxicity in native kidneys of patients with chronic glomerulopathies. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040501 |
| Use of sirolimus-eluting coronary stents in routine clinical practice. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040501 |
| Day in and day out. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040501 |
| Economic evaluation of everolimus versus mycophenolate mofetil in combination with cyclosporine and prednisolone in de novo renal transplant recipients. | Transplant international : official journal of the European Society for Organ Transplantation 20040501 |
| Local application of rapamycin inhibits neointimal hyperplasia in experimental vein grafts. | The Annals of thoracic surgery 20040501 |
| Sirolimus and tacrolimus without methotrexate as graft-versus-host disease prophylaxis after matched related donor peripheral blood stem cell transplantation. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20040501 |
| Rapamycin-associated post-transplantation glomerulonephritis and its remission after reintroduction of calcineurin-inhibitor therapy. | Transplant international : official journal of the European Society for Organ Transplantation 20040501 |
| Sirolimus-induced hyperlipidaemia in liver transplant recipients is not dose-dependent. | Alimentary pharmacology & therapeutics 20040501 |
| The TOR pathway: a target for cancer therapy. | Nature reviews. Cancer 20040501 |
| Clinical impact of stent construction and design in percutaneous coronary intervention. | American heart journal 20040501 |
| Airway anastomosis complications in de novo lung transplantation with sirolimus-based immunosuppression. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20040501 |
| [Active stents: towards total prevention of restenosis?]. | Pathologie-biologie 20040501 |
| Effectiveness of the sirolimus-eluting stent in the treatment of saphenous vein graft disease. | The Journal of invasive cardiology 20040501 |
| Drug-eluting stents and saphenous vein graft intervention. | The Journal of invasive cardiology 20040501 |
| Rapamycin inhibits release of tumor necrosis factor-alpha from human vascular smooth muscle cells. | The American surgeon 20040501 |
| Chemical dimerizers and three-hybrid systems: scanning the proteome for targets of organic small molecules. | Chemistry & biology 20040501 |
| Selective modulation of some forms of schaffer collateral-CA1 synaptic plasticity in mice with a disruption of the CPEB-1 gene. | Learning & memory (Cold Spring Harbor, N.Y.) 20040501 |
| Sirolimus-eluting stent implantation in a heart transplant recipient. | Italian heart journal : official journal of the Italian Federation of Cardiology 20040501 |
| Rapamycin even when combined with cyclosporine attenuates tumor growth but does not induce regression of established walker sarcomas. | Transplantation proceedings 20040501 |
| Immunosuppression in pancreas transplantation: mycophenolate mofetil versus sirolimus. | Transplantation proceedings 20040501 |
| Long-term outcome of sirolimus rescue in kidney-pancreas transplantation. | Transplantation proceedings 20040501 |
| Islet of Langerhans allogeneic transplantation at the University of Geneva in the steroid free era in islet after kidney and simultaneous islet-kidney transplantations. | Transplantation proceedings 20040501 |
| Glucose-induced binding of the polypyrimidine tract-binding protein (PTB) to the 3'-untranslated region of the insulin mRNA (ins-PRS) is inhibited by rapamycin. | Molecular and cellular biochemistry 20040501 |
| High-dose bolus tirofiban and sirolimus eluting stent versus abiciximab and bare metal stent in acute myocardial infarction (STRATEGY) study--protocol design and demography of the first 100 patients. | Cardiovascular drugs and therapy 20040501 |
| [From sirolimus to the Cypher stent: stages of the victory against restenosis]. | Annales de cardiologie et d'angeiologie 20040501 |
| [Sirolimus endoprosthesis: data from the RAVEL and the SIRIUS study]. | Annales de cardiologie et d'angeiologie 20040501 |
| [The E-SIRIUS and the new SIRIUS clinical trials]. | Annales de cardiologie et d'angeiologie 20040501 |
| [The e-Cypher registry: objectives and organization]. | Annales de cardiologie et d'angeiologie 20040501 |
| [The national registry EVASTENT: cost-effectiveness analysis of the sirolimus active stent in diabetic and non-diabetic patients]. | Annales de cardiologie et d'angeiologie 20040501 |
| [BRIDGE registry (safety and efficacy registry Bx Cyper stent in the RevascularIzation of patients with siGnificative risk of rEstenosis): protocol description and preliminary results]. | Annales de cardiologie et d'angeiologie 20040501 |
| [Sirolimus-releasing coronary stent: lessons from the Rotterdam experience]. | Annales de cardiologie et d'angeiologie 20040501 |
| [Cypher stent: the German registry. Results of the German prospective multicenter registry on Cypher]. | Annales de cardiologie et d'angeiologie 20040501 |
| [The Cypher stent: most recent news of the 2004 Congress of the American College of Cardiology]. | Annales de cardiologie et d'angeiologie 20040501 |
| [Cypher: ongoing studies]. | Annales de cardiologie et d'angeiologie 20040501 |
| [The Siro-ISR registry: treatment of intra-stent restenosis with the sirolimus stent in the real world]. | Annales de cardiologie et d'angeiologie 20040501 |
| [Cypher stent: upcoming clinical studies]. | Annales de cardiologie et d'angeiologie 20040501 |
| ['Active' endoprosthesis with in situ release of an antimitotic or cytostatic drug: a revolution that cannot do without thought]. | Annales de cardiologie et d'angeiologie 20040501 |
| Actin cytoskeleton is required for nuclear accumulation of Gln3 in response to nitrogen limitation but not rapamycin treatment in Saccharomyces cerevisiae. | The Journal of biological chemistry 20040430 |
| Stent thrombosis after successful sirolimus-eluting stent implantation. | Circulation 20040427 |
| Synergistic effects of sirolimus with cyclosporine and tacrolimus: analysis of immunosuppression on lymphocyte proliferation and activation in rat whole blood. | Transplantation 20040427 |
| Sirolimus-associated pulmonary toxicity. | Transplantation 20040427 |
| Comparison of sirolimus-based calcineurin inhibitor-sparing and calcineurin inhibitor-free regimens in cadaveric renal transplantation. | Transplantation 20040427 |
| Niban gene is commonly expressed in the renal tumors: a new candidate marker for renal carcinogenesis. | Oncogene 20040422 |
| Phosphorylation of eucaryotic translation initiation factor 4B Ser422 is modulated by S6 kinases. | The EMBO journal 20040421 |
| Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status. | The Journal of biological chemistry 20040416 |
| Opioid-induced cardioprotection occurs via glycogen synthase kinase beta inhibition during reperfusion in intact rat hearts. | Circulation research 20040416 |
| TOR kinase and Ran are downstream from PI3K/Akt in H2O2-induced mitosis. | Journal of cellular biochemistry 20040415 |
| The novel cyclophilin binding compound, sanglifehrin A, disassociates G1 cell cycle arrest from tolerance induction. | Journal of immunology (Baltimore, Md. : 1950) 20040415 |
| Rapamycin sensitizes multiple myeloma cells to apoptosis induced by dexamethasone. | Blood 20040415 |
| Lymphedema associated with sirolimus in renal transplant recipients. | Transplantation 20040415 |
| TOR complex 1 includes a novel component, Tco89p (YPL180w), and cooperates with Ssd1p to maintain cellular integrity in Saccharomyces cerevisiae. | The Journal of biological chemistry 20040409 |
| Treatment of multivessel coronary artery disease with sirolimus-eluting stent implantation: immediate and mid-term results. | Journal of the American College of Cardiology 20040407 |
| Mammalian target of rapamycin regulates IRS-1 serine 307 phosphorylation. | Biochemical and biophysical research communications 20040402 |
| New rapamycin derivatives by precursor-directed biosynthesis. | Chembiochem : a European journal of chemical biology 20040402 |
| Rapamycin control of exocrine protein levels in saliva after adenoviral vector-mediated gene transfer. | Gene therapy 20040401 |
| Arginine and Leucine regulate p70 S6 kinase and 4E-BP1 in intestinal epithelial cells. | International journal of molecular medicine 20040401 |
| IL2-dependent phosphorylation of 40S ribosomal protein S6 is controlled by PI-3K/mTOR signalling in CTLL2 cells. | International journal of molecular medicine 20040401 |
| Multiple combination therapies involving blockade of ICOS/B7RP-1 costimulation facilitate long-term islet allograft survival. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040401 |
| Everolimus with optimized cyclosporine dosing in renal transplant recipients: 6-month safety and efficacy results of two randomized studies. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040401 |
| An investigation into signal transduction mechanisms involved in insulin-induced long-term depression in the CA1 region of the hippocampus. | Journal of neurochemistry 20040401 |
| Role of FKBP12.6 in hypoxia- and norepinephrine-induced Ca2+ release and contraction in pulmonary artery myocytes. | Cell calcium 20040401 |
| Rapamycin effects transcriptional programs in smooth muscle cells controlling proliferative and inflammatory properties. | Molecular pharmacology 20040401 |
| Safety and pharmacokinetics of ascending single doses of sirolimus (Rapamune, rapamycin) in pediatric patients with stable chronic renal failure undergoing dialysis. | Pediatric transplantation 20040401 |
| Short sirolimus half-life in pediatric renal transplant recipients on a calcineurin inhibitor-free protocol. | Pediatric transplantation 20040401 |
| Very long sirolimus-eluting stent implantation for de novo coronary lesions. | The American journal of cardiology 20040401 |
| Local drug delivery in restenosis injury: thermoresponsive co-polymers as potential drug delivery systems. | Pharmacology & therapeutics 20040401 |
| Immunosuppressants and skin cancer in transplant patients: focus on rapamycin. | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20040401 |
| Clinical and angiographic outcomes after overdilatation of undersized sirolimus-eluting stents with largely oversized balloons: an observational study. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040401 |
| Overstretching undersized drug-eluting stents: a temporary solution. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040401 |
| Sirolimus-associated diffuse alveolar hemorrhage. | Mayo Clinic proceedings 20040401 |
| Dissociation of raptor from mTOR is a mechanism of rapamycin-induced inhibition of mTOR function. | Genes to cells : devoted to molecular & cellular mechanisms 20040401 |
| Sirolimus-eluting stents in the canine cerebral vasculature: a prospective, randomized, blinded assessment of safety and vessel response. | Journal of neurosurgery 20040401 |
| 'Real life' use of sirolimus-eluting coronary stents in Germany. Results from the prospective multi-centre German Cypher Registry. | Zeitschrift fur Kardiologie 20040401 |
| Sirolimus increases transforming growth factor-beta1 expression and potentiates chronic cyclosporine nephrotoxicity. | Kidney international 20040401 |
| Sirolimus in kidney transplantation from marginal donors. | Transplantation proceedings 20040401 |
| Platelet-Independent defect in hemostasis associated with sirolimus use. | Transplantation proceedings 20040401 |
| Severe rhabdomyolysis and acute renal failure in a kidney transplant patient treated with tacrolimus and chimaeric CD25 monoclonal antibody. | Transplantation proceedings 20040401 |
| PI3-kinase and TOR: PIKTORing cell growth. | Seminars in cell & developmental biology 20040401 |
| Islet allograft survival in nonhuman primates immunosuppressed with basiliximab, RAD, and FTY720. | Transplantation 20040327 |
| Therapeutic drug monitoring for sirolimus in whole blood of organ transplants by high-performance liquid chromatography with ultraviolet detection. | Journal of chromatography. A 20040326 |
| Clinical, angiographic, and procedural predictors of angiographic restenosis after sirolimus-eluting stent implantation in complex patients: an evaluation from the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) study. | Circulation 20040323 |
| Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. | Biochemical and biophysical research communications 20040319 |
| Cancer: survival pathways meet their end. | Nature 20040318 |
| Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy. | Nature 20040318 |
| Differential regulation of MAP2 and alphaCamKII expression in hippocampal neurones by forskolin and calcium ionophore treatment. | Brain research. Molecular brain research 20040317 |
| The Canadian study of the sirolimus-eluting stent in the treatment of patients with long de novo lesions in small native coronary arteries (C-SIRIUS). | Journal of the American College of Cardiology 20040317 |
| Sirolimus-eluting stents: does a great stent still need a good interventionalist? | Journal of the American College of Cardiology 20040317 |
| Randomized study to evaluate sirolimus-eluting stents implanted at coronary bifurcation lesions. | Circulation 20040316 |
| Unique, highly proliferative growth phenotype expressed by embryonic and neointimal smooth muscle cells is driven by constitutive Akt, mTOR, and p70S6K signaling and is actively repressed by PTEN. | Circulation 20040316 |
| Combination therapy with sirolimus and mycophenolate mofetil: effects on the kidney and on transforming growth factor-beta1. | Transplantation 20040315 |
| Conversion to sirolimus: a successful treatment for posttransplantation Kaposi's sarcoma. | Transplantation 20040315 |
| Molecular imaging of drug-modulated protein-protein interactions in living subjects. | Cancer research 20040315 |
| Rapamycin-induced endothelial cell death and tumor vessel thrombosis potentiate cytotoxic therapy against pancreatic cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040315 |
| Gln3 phosphorylation and intracellular localization in nutrient limitation and starvation differ from those generated by rapamycin inhibition of Tor1/2 in Saccharomyces cerevisiae. | The Journal of biological chemistry 20040312 |
| Contribution of stent underexpansion to recurrence after sirolimus-eluting stent implantation for in-stent restenosis. | Circulation 20040309 |
| Drug-eluting stent restenosis rates? | Circulation 20040309 |
| Protein kinase A phosphorylation at serine-2808 of the cardiac Ca2+-release channel (ryanodine receptor) does not dissociate 12.6-kDa FK506-binding protein (FKBP12.6). | Circulation research 20040305 |
| The mTOR/p70 S6K1 pathway regulates vascular smooth muscle cell differentiation. | American journal of physiology. Cell physiology 20040301 |
| Mammalian target of rapamycin (mTOR) Inhibitors. | Current oncology reports 20040301 |
| Rapamycin plays a new role as differentiator of vascular smooth muscle phenotype. focus on 'The mTOR/p70 S6K1 pathway regulates vascular smooth muscle differentiation'. | American journal of physiology. Cell physiology 20040301 |
| Evidence for 'lumen sealing' with sirolimus eluting stents in the treatment of complex coronary artery dissection. | Heart (British Cardiac Society) 20040301 |
| Long-term benefits with sirolimus-based therapy after early cyclosporine withdrawal. | Journal of the American Society of Nephrology : JASN 20040301 |
| Synergistic use of sirolimus-eluting stents and intravascular ultrasound for the treatment of unprotected left main and vein graft disease. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040301 |
| Electron microscopic and biochemical study of the effects of rapamycin on glycogen autophagy in the newborn rat liver. | Microscopy research and technique 20040301 |
| Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040301 |
| Treatment of very small vessels with 2.25-mm diameter sirolimus-eluting stents (from the RESEARCH registry). | The American journal of cardiology 20040301 |
| Economic impact of drug-eluting stents on hospital systems: a disease-state model. | American heart journal 20040301 |
| Cell signalling of glucagon-like peptide-1 action in rat skeletal muscle. | The Journal of endocrinology 20040301 |
| Steroid immunosuppression in kidney transplantation: a passing era. | The Journal of surgical research 20040301 |
| Blockage of 2-deoxy-D-ribose-induced angiogenesis with rapamycin counteracts a thymidine phosphorylase-based escape mechanism available for colon cancer under 5-fluorouracil therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040301 |
| Sirolimus-eluting coronary stent. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040301 |
| Renal recovery after conversion to a calcineurin inhibitor-free immunosuppression in late cardiac transplant recipients. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20040301 |
| Effects of aerobic exercise training on the protein kinase B (PKB)/mammalian target of rapamycin (mTOR) signaling pathway in aged skeletal muscle. | Experimental gerontology 20040301 |
| Use of cyclosporine in renal transplantation. | Transplantation proceedings 20040301 |
| Immunosuppression for pancreatic islet transplantation. | Transplantation proceedings 20040301 |
| The evolving experience using everolimus in clinical transplantation. | Transplantation proceedings 20040301 |
| Experience with everolimus. | Transplantation proceedings 20040301 |
| The promise of C2, Simulect, and Certican in heart transplantation. | Transplantation proceedings 20040301 |
| Promise of Neoral C2, basiliximab, and everolimus in lung transplantation. | Transplantation proceedings 20040301 |
| Rapamycin analogs for stent-based local drug delivery. Everolimus- and tacrolimus-eluting stents. | Herz 20040301 |
| ABT-578-eluting stents. The promising successor of sirolimus- and paclitaxel-eluting stent concepts? | Herz 20040301 |
| Polymer-sirolimus-eluting stents in de novo lesions. | Herz 20040301 |
| [Safety and current indications during 'real life' use of sirolimus-eluting coronary stents in Germany. Results from the prospective multicenter German Cypher Registry]. | Herz 20040301 |
| Classification and current treatment options of in-stent restenosis. Present status and future perspectives. | Herz 20040301 |
| Drug-eluting stents for in-stent restenosis and acute myocardial infarction: present data from nonrandomized studies. | Herz 20040301 |
| [Do drug-eluting stents influence the spectrum of coronary artery bypass surgery?]. | Herz 20040301 |
| Drug eluting stents in the infrainguinal circulation. | Techniques in vascular and interventional radiology 20040301 |
| Cardiac allograft vasculopathy: advances in understanding its pathophysiology, prevention, and treatment. | Current opinion in cardiology 20040301 |
| Low toxicity immunosuppressive protocols in renal transplantation. | The Keio journal of medicine 20040301 |
| Molecule of the month. Everolimus. | Drug news & perspectives 20040301 |
| Rpd3p relocation mediates a transcriptional response to rapamycin in yeast. | Chemistry & biology 20040301 |
| Dose-dependent inhibition of myointimal hyperplasia by orally administered rapamycin. | Annals of vascular surgery 20040301 |
| Amino acids and insulin control autophagic proteolysis through different signaling pathways in relation to mTOR in isolated rat hepatocytes. | The Journal of biological chemistry 20040227 |
| Mycophenolate mofetil and sirolimus as calcineurin inhibitor-free immunosuppression for late cardiac-transplant recipients with chronic renal failure. | Transplantation 20040227 |
| Paradigm shifts in cardiovascular medicine. | Journal of the American College of Cardiology 20040218 |
| Short- and long-term clinical benefit of sirolimus-eluting stents compared to conventional bare stents for patients with acute myocardial infarction. | Journal of the American College of Cardiology 20040218 |
| Localized hypersensitivity and late coronary thrombosis secondary to a sirolimus-eluting stent: should we be cautious? | Circulation 20040217 |
| Mammalian target of rapamycin inhibition as therapy for hematologic malignancies. | Cancer 20040215 |
| Sirolimus and ketoconazole co-prescription in renal transplant recipients. | Transplantation 20040215 |
| Intravascular ultrasound study of effects of overlapping sirolimus-eluting stents. | The American journal of cardiology 20040215 |
| mTOR-dependent activation of the transcription factor TIF-IA links rRNA synthesis to nutrient availability. | Genes & development 20040215 |
| Analysis of 1-year clinical outcomes in the SIRIUS trial: a randomized trial of a sirolimus-eluting stent versus a standard stent in patients at high risk for coronary restenosis. | Circulation 20040210 |
| [New devices for coronary interventions in patients with acute coronary syndrome]. | Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040210 |
| [Irritant cough and sub-febrile temperature under immunosuppression]. | Praxis 20040204 |
| Dead cells don't form tumors: HIF-dependent cytotoxins. | Cell cycle (Georgetown, Tex.) 20040201 |
| Novel therapeutic molecular targets for prostate cancer: the mTOR signaling pathway and epidermal growth factor receptor. | The Journal of urology 20040201 |
| Mechanistic insights into impaired dendritic cell function by rapamycin: inhibition of Jak2/Stat4 signaling pathway. | Journal of immunology (Baltimore, Md. : 1950) 20040201 |
| Regional haemodynamic effects of cyclosporine A, tacrolimus and sirolimus in conscious rats. | British journal of pharmacology 20040201 |
| Kissing sirolimus-eluting stents for the treatment of left main coronary artery stenosis. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040201 |
| Treatment of long, diffuse in-stent restenosis with sirolimus-eluting stents. | The Journal of invasive cardiology 20040201 |
| Effect of sirolimus on infection incidence in liver transplant recipients. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20040201 |
| Stent restenosis and the use of drug-eluting stents in patients with diabetes mellitus. | Current diabetes reports 20040201 |
| Determinants of rapamycin sensitivity in breast cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040201 |
| [Is systematic use of drug-eluting stents justified? Arguments in favour]. | Revista espanola de cardiologia 20040201 |
| [Is systematic use of drug-eluting stents justified? Arguments against]. | Revista espanola de cardiologia 20040201 |
| [Sirolimus-eluting stents to treat lesions with a high risk of restenosis. Six-month clinical follow-up in the first 100 patients]. | Revista espanola de cardiologia 20040201 |
| [Use of sirolimus-eluting stents in complex lesions: clinical and angiographic follow-up]. | Revista espanola de cardiologia 20040201 |
| Inhibition of insulin signaling and adipogenesis by rapamycin: effect on phosphorylation of p70 S6 kinase vs eIF4E-BP1. | International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 20040201 |
| Human renal allograft rejection despite the absence of allogeneic passenger leukocytes. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040201 |
| Is everolimus useful in preventing allograft rejection and vasculopathy after heart transplant? | Expert opinion on investigational drugs 20040201 |
| Drug-eluting stents: a new treatment in the prevention of restenosis. Part I: Experimental studies. | Acta cardiologica 20040201 |
| [Thrombosis caused by active rapamycin stents]. | Archives des maladies du coeur et des vaisseaux 20040201 |
| Everolimus: a proliferation signal inhibitor targeting primary causes of allograft dysfunction. | Drugs of today (Barcelona, Spain : 1998) 20040201 |
| Stents put on a new drug coat. The coat is thin and washes off, but offers major protection. | Heart advisor 20040201 |
| An open-label randomized trial of the safety and efficacy of sirolimus vs. azathioprine in living related renal allograft recipients receiving cyclosporine and prednisone combination. | Clinical transplantation 20040201 |
| Observations regarding the use of sirolimus and tacrolimus in high-risk cadaveric renal transplantation. | Clinical transplantation 20040201 |
| Nutrient-dependent and insulin-stimulated phosphorylation of insulin receptor substrate-1 on serine 302 correlates with increased insulin signaling. | The Journal of biological chemistry 20040130 |
| The N-terminal domain of yeast Bap2 permease is phosphorylated dependently on the Npr1 kinase in response to starvation. | FEMS microbiology letters 20040130 |
| Acceleration of apoptosis in CD4+CD8+ thymocytes by rapamycin accompanied by increased CD4+CD25+ T cells in the periphery. | Transplantation 20040127 |
| A randomized long-term trial of tacrolimus and sirolimus versus tacrolimus and mycophenolate mofetil versus cyclosporine (NEORAL) and sirolimus in renal transplantation. I. Drug interactions and rejection at one year. | Transplantation 20040127 |
| A randomized long-term trial of tacrolimus/sirolimus versus tacrolimus/mycophenolate mofetil versus cyclosporine (NEORAL)/sirolimus in renal transplantation. II. Survival, function, and protocol compliance at 1 year. | Transplantation 20040127 |
| Everolimus and mycophenolate mofetil are potent inhibitors of fibroblast proliferation after lung transplantation. | Transplantation 20040127 |
| AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression. | The Journal of biological chemistry 20040123 |
| Sirolimus-eluting coronary stents. | The New England journal of medicine 20040122 |
| Sirolimus-eluting coronary stents. | The New England journal of medicine 20040122 |
| Unrestricted utilization of sirolimus-eluting stents compared with conventional bare stent implantation in the 'real world': the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry. | Circulation 20040120 |
| Functional characterization of a maize ribosomal S6 protein kinase (ZmS6K), a plant ortholog of metazoan p70(S6K). | Biochemistry 20040120 |
| Bringing reality to drug-eluting stents. | Circulation 20040120 |
| 'Me-too' products--friend or foe? | The New England journal of medicine 20040115 |
| Thrombotic microangiopathy associated with combined sirolimus and tacrolimus immunosuppression after intestinal transplantation. | Transplantation 20040115 |
| Rapamycin inhibits cdk4 activation, p 21(WAF1/CIP1) expression and G1-phase progression in transformed mouse fibroblasts. | International journal of cancer 20040110 |
| Rapamycin-resistant proliferation of CD8+ T cells correlates with p27kip1 down-regulation and bcl-xL induction, and is prevented by an inhibitor of phosphoinositide 3-kinase activity. | The Journal of biological chemistry 20040109 |
| Golgi membranes remain segregated from the endoplasmic reticulum during mitosis in mammalian cells. | Cell 20040109 |
| Differential effects of modern immunosuppressive agents on the development of intimal hyperplasia. | Transplant international : official journal of the European Society for Organ Transplantation 20040101 |
| The role of phosphatases in TOR signaling in yeast. | Current topics in microbiology and immunology 20040101 |
| Nutrient signaling through TOR kinases controls gene expression and cellular differentiation in fungi. | Current topics in microbiology and immunology 20040101 |
| The fission yeast TOR proteins and the rapamycin response: an unexpected tale. | Current topics in microbiology and immunology 20040101 |
| Plant growth and the TOR pathway. | Current topics in microbiology and immunology 20040101 |
| TOR action in mammalian cells and in Caenorhabditis elegans. | Current topics in microbiology and immunology 20040101 |
| mTOR signaling to translation. | Current topics in microbiology and immunology 20040101 |
| Raptor and mTOR: subunits of a nutrient-sensitive complex. | Current topics in microbiology and immunology 20040101 |
| mTOR as a positive regulator of tumor cell responses to hypoxia. | Current topics in microbiology and immunology 20040101 |
| Retroviral oncogenes and TOR. | Current topics in microbiology and immunology 20040101 |
| mTOR as a target for cancer therapy. | Current topics in microbiology and immunology 20040101 |
| CYP3A4-transfected Caco-2 cells as a tool for understanding biochemical absorption barriers: studies with sirolimus and midazolam. | The Journal of pharmacology and experimental therapeutics 20040101 |
| Non-coplanar 2,2',3,5',6-pentachlorobiphenyl (PCB 95) amplifies ionotropic glutamate receptor signaling in embryonic cerebellar granule neurons by a mechanism involving ryanodine receptors. | Toxicological sciences : an official journal of the Society of Toxicology 20040101 |
| Drug-eluting stents. A review of the current literature. | Cardiology in review 20040101 |
| mTOR controls cell cycle progression through its cell growth effectors S6K1 and 4E-BP1/eukaryotic translation initiation factor 4E. | Molecular and cellular biology 20040101 |
| Testosterone concentrations and sirolimus in male renal transplant patients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040101 |
| Sirolimus-induced pneumonitis: three cases and a review of the literature. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20040101 |
| Intravascular ultrasound evaluation after sirolimus eluting stent implantation for de novo and in-stent restenosis lesions. | European heart journal 20040101 |
| Addition of sirolimus to cyclosporine delays the recovery from delayed graft function but does not affect 1-year graft function. | Journal of the American Society of Nephrology : JASN 20040101 |
| Stent fracture and restenosis in the drug-eluting stent era. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20040101 |
| Rapamycin attenuates atherosclerosis induced by dietary cholesterol in apolipoprotein-deficient mice through a p27 Kip1 -independent pathway. | Atherosclerosis 20040101 |
| Health-related quality of life outcomes after kidney transplantation. | Health and quality of life outcomes 20040101 |
| Sirolimus-eluting stents inhibit neointimal hyperplasia in diabetic patients. Insights from the RAVEL Trial. | European heart journal 20040101 |
| Drug immunosuppression therapy for adult heart transplantation. Part 1: immune response to allograft and mechanism of action of immunosuppressants. | The Annals of thoracic surgery 20040101 |
| Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells. | Cancer research 20040101 |
| Rapamycin inhibits the growth and metastatic progression of non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040101 |
| Clinical pharmacokinetics of everolimus. | Clinical pharmacokinetics 20040101 |
| [Prevention of in-stent restenosis: towards an in situ treatment?]. | Medecine sciences : M/S 20040101 |
| Update on sirolimus drug-eluting stents. | Current pharmaceutical design 20040101 |
| Arsenite induces p70S6K1 activation and HIF-1alpha expression in prostate cancer cells. | Molecular and cellular biochemistry 20040101 |
| The management of immunosuppression: the art and the science. | Critical care nursing quarterly 20040101 |
| Transforming growth factor-beta induces Cdk2 relocalization to the cytoplasm coincident with dephosphorylation of retinoblastoma tumor suppressor protein. | Breast cancer research : BCR 20040101 |
| Everolimus/cyclosporine interactions on bile flow and biliary excretion of bile salts and cholesterol in rats. | Digestive diseases and sciences 20040101 |
| Sirolimus: a ten-year perspective. | Transplantation proceedings 20040101 |
| Adverse events and Cypher stents. | FDA consumer 20040101 |
| Immunophilin ligands decrease release of pro-inflammatory cytokines (IL-1beta, TNF-alpha and IL-2 in rat astrocyte cultures exposed to simulated ischemia in vitro. | Polish journal of pharmacology 20040101 |
| Everolimus. | Drugs 20040101 |
| Translation of the radioresistance kinase TLK1B is induced by gamma-irradiation through activation of mTOR and phosphorylation of 4E-BP1. | BMC molecular biology 20040101 |
| Lessons from the E-SIRIUS trial. | Italian heart journal : official journal of the Italian Federation of Cardiology 20040101 |
| Sirolimus-eluting coronary stents: novel devices for the management of coronary artery disease. | American journal of therapeutics 20040101 |
| Signaling of angiotensin II-induced vascular protein synthesis in conduit and resistance arteries in vivo. | BMC cardiovascular disorders 20040101 |
| New immunosuppressive strategies in renal transplant recipients. | Journal of nephrology 20040101 |
| Overcoming endocrine therapy resistance by signal transduction inhibition. | The oncologist 20040101 |
| Everolimus for stent-based intracoronary applications. | Reviews in cardiovascular medicine 20040101 |
| Liposomal formulations of tacrolimus and rapamycin increase graft survival and fiber outgrowth of dopaminergic grafts. | Cell transplantation 20040101 |
| Update on transplant pharmacology: sirolimus. | Dimensions of critical care nursing : DCCN 20040101 |
| [Stents without restenosis--true or a myth?]. | Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti 20040101 |
| Conversion to sirolimus-based maintenance immunosuppression using daclizumab bridge therapy in renal transplant recipients. | Clinical transplantation 20040101 |
| Augmentation of T-cell apoptosis by immunosuppressive agents. | Clinical transplantation 20040101 |
| [De novo hemolytic uremic syndrome in a kidney-pancreas recipient in the postoperative period]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101 |
| [Interstitial pneumonitis associated with sirolimus administration in a renal transplantation patient: a clinical case]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101 |
| [Calcineurin-inhibitor-free immunosuppression in early renal transplantation]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101 |
| [Everolimus: immunosuppression with antilymphoproliferative therapy]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20040101 |
| Functional analysis of APC-Cdh1. | Methods in molecular biology (Clifton, N.J.) 20040101 |
| [Italian Consensus Conference on drug-eluting stents]. | Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology 20040101 |
| Induction sirolimus and delayed graft function after deceased donor kidney transplantation in the United States. | American journal of nephrology 20040101 |
| Low-dose sirolimus in combination with mycophenolate mofetil improves kidney graft function late after renal transplantation and suggests pharmacokinetic interaction of both immunosuppressive drugs. | Kidney & blood pressure research 20040101 |
| Sirolimus dosage during and after conversion from calcineurin inhibitor therapy to sirolimus in chronic kidney transplant patients. | Kidney & blood pressure research 20040101 |
| New targets for therapy in breast cancer: mammalian target of rapamycin (mTOR) antagonists. | Breast cancer research : BCR 20040101 |
| [Vascular and interventional radiology]. | Journal de radiologie 20040101 |
| Effect of rapamycin on cytokine profile in kidney transplant recipients treated with triple drug therapy. | Transplantation proceedings 20040101 |
| Donor stem cell infusion after non-myeloablative conditioning for tolerance induction to HLA mismatched adult living-donor liver graft. | Transplant immunology 20040101 |
| Immune status assay (ISA): a noninvasive procedure for studying allograft rejection. | Transplant immunology 20040101 |
| Method development for the quantitation of ABT-578 in rabbit artery tissue by 96-well liquid-liquid extraction and liquid chromatography/tandem mass spectrometric detection. | Rapid communications in mass spectrometry : RCM 20040101 |
| Empirical assessment of the impact of drug-eluting stents on the rate of use of coronary revascularization procedures. | International journal of technology assessment in health care 20040101 |
| Addition of heparin to contrast media is associated with increased bleeding and peripheral vascular complications during percutaneous coronary intervention with bivalirudin and drug-eluting stents. | Cardiovascular radiation medicine 20040101 |
| Molecular targeting: PI3 kinase pathway. | Annals of oncology : official journal of the European Society for Medical Oncology 20040101 |
| Pamidronate resistance and associated low ras levels in breast cancer cells: a role for combinatorial therapy. | Annals of clinical and laboratory science 20040101 |
| [First experience of the use of sirolimus covered stents output in the treatment of ischemic heart disease]. | Kardiologiia 20040101 |
| Asymptomatic late stent thrombosis after sirolimus stent implantation. | Cardiovascular radiation medicine 20040101 |
| Rapamycin inhibits Akt-mediated oncogenic transformation and tumor growth. | Anticancer research 20040101 |
| Drug-coated stents: preventing restenosis in coronary artery disease. | The Journal of cardiovascular nursing 20040101 |
| [Restenosis inside the stent: treatment and prevention]. | Klinicheskaia meditsina 20040101 |
| Temsirolimus: CCI 779, CCI-779, cell cycle inhibitor-779. | Drugs in R&D 20040101 |
| Immunomodulatory therapy in ophthalmology - is there a place for topical application? | Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20040101 |
| Therapeutic monitoring of immunosuppressant drugs. Where are we? | Clinical chemistry and laboratory medicine 20040101 |
| The pleiotropic effects of mTor inhibitors. | Journal of nephrology 20040101 |
| Sirolimus-based immunosuppression: present state of the art. | Journal of nephrology 20040101 |
| From balloon angioplasty to drug-eluting stents: revolution or evolution? | The American heart hospital journal 20040101 |
| Drug-eluting stents: are they really safe? | The American heart hospital journal 20040101 |
| Differential effects of rapamycin, cyclosporine A, and FK506 on human coronary artery smooth muscle cell proliferation and signalling. | Vascular pharmacology 20040101 |
| Sirolimus therapy in orthotopic liver transplant (OLT) recipients with acute renal insufficiency. | Digestive diseases and sciences 20040101 |
| [Cancer after kidney transplantation]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20040101 |
| An evidence-based approach to the use of drug-eluting stents in clinical practice. | The American heart hospital journal 20040101 |
| Late thrombosis in cypher stents after the discontinuation of antiplatelet therapy. | Cardiovascular radiation medicine 20040101 |
| CNI-sparing regimens within the liver transplant setting: experiences of a single center. | Clinical transplants 20040101 |
| The impact of sirolimus, mycophenolate mofetil, cyclosporine, azathioprine, and steroids on wound healing in 513 kidney-transplant recipients. | Transplantation 20031227 |
| Sirolimus inhibits oxidative burst activity in transplant recipients. | Transplantation 20031227 |
| Sirolimus myopathy. | Transplantation 20031227 |
| Rapamycin induces the fusion-type independent downregulation of the EWS/FLI-1 proteins and inhibits Ewing's sarcoma cell proliferation. | Oncogene 20031218 |
| Blocking the monocyte chemoattractant protein-1/CCR2 chemokine pathway induces permanent survival of islet allografts through a programmed death-1 ligand-1-dependent mechanism. | Journal of immunology (Baltimore, Md. : 1950) 20031215 |
| Sirolimus delays recovery of rat kidney transplants after ischemia-reperfusion injury. | Transplantation 20031215 |
| Elevated portal vein drug levels of sirolimus and tacrolimus in islet transplant recipients: local immunosuppression or islet toxicity? | Transplantation 20031215 |
| Sirolimus-atorvastatin drug interaction in the pancreatic islet transplant recipient. | Transplantation 20031215 |
| Everolimus in cardiac-transplant recipients. | The New England journal of medicine 20031204 |
| Long-term follow-up of incomplete stent apposition in patients who received sirolimus-eluting stent for de novo coronary lesions: an intravascular ultrasound analysis. | Circulation 20031202 |
| Insulin-dependent signaling regulates azurophil granule-selective macroautophagy in human myeloblastic cells. | Journal of leukocyte biology 20031201 |
| Long-term treatment with insulin induces apoptosis in brown adipocytes: role of oxidative stress. | Endocrinology 20031201 |
| Ortho-substituted PCBs kill thymocytes. | Toxicological sciences : an official journal of the Society of Toxicology 20031201 |
| New therapeutic strategies for soft tissue sarcomas. | Current treatment options in oncology 20031201 |
| Homodirectional changes in transcriptome composition and mRNA translation induced by rapamycin and heat shock. | Nature structural biology 20031201 |
| Pharmacologic prevention of both restenosis and atherosclerosis progression: AGI-1067, probucol, statins, folic acid and other therapies. | Current opinion in lipidology 20031201 |
| Restenosis due to underexpansion of sirolimus-eluting stent in a bifurcation lesion. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20031201 |
| Late stent thrombosis after implantation of a sirolimus-eluting stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20031201 |
| The porcine coronary model of in-stent restenosis: current status in the era of drug-eluting stents. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20031201 |
| Influence of delayed initiation of cyclosporine on everolimus pharmacokinetics in de novo renal transplant patients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20031201 |
| Antiproliferative coatings for the treatment of coronary heart disease:. what are the targets and which are the tools? | Journal of interventional cardiology 20031201 |
| Treatment of bifurcation coronary lesions: a review of current techniques and outcome. | Journal of interventional cardiology 20031201 |
| Benefits and risks of solitary islet transplantation for type 1 diabetes using steroid-sparing immunosuppression: the National Institutes of Health experience. | Diabetes care 20031201 |
| Usefulness of shear stress pattern in predicting neointima distribution in sirolimus-eluting stents in coronary arteries. | The American journal of cardiology 20031201 |
| Assessment of immunosuppressive drug interactions: inhibition of lymphocyte function in peripheral human blood. | Journal of immunological methods 20031201 |
| Differential effects of rapamycin on mammalian target of rapamycin signaling functions in mammalian cells. | Cancer research 20031201 |
| Rapamycin has no effect on fibrosis-associated gene expression or extracellular matrix accumulation when administered to animals with established or early allograft vasculopathy. | The Journal of thoracic and cardiovascular surgery 20031201 |
| TOR and PKA signaling pathways converge on the protein kinase Rim15 to control entry into G0. | Molecular cell 20031201 |
| Conditional protein alleles using knockin mice and a chemical inducer of dimerization. | Molecular cell 20031201 |
| Sirolimus therapy in orthotopic liver transplant recipients with calcineurin inhibitor related chronic renal insufficiency. | Transplantation proceedings 20031201 |
| Effect of sirolimus on the cholesterol content of aortic arch in ApoE knockout mice. | Transplantation proceedings 20031201 |
| Regulating cell surface glycosylation by small molecule control of enzyme localization. | Chemistry & biology 20031201 |
| [Immunomodulation in penetrating keratoplasty. Current status and perspectives]. | Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20031201 |
| Current immunosuppressive agents: efficacy, side effects, and utilization. | Pediatric clinics of North America 20031201 |
| The arsenal. The latest in drugs, surgery, and devices. | U.S. news & world report 20031201 |
| Sirolimus add-on rescue therapy can benefit patients with chronic renal allograft dysfunction. | Journal of the Formosan Medical Association = Taiwan yi zhi 20031201 |
| Angioplasty: no more repeats. | The Johns Hopkins medical letter health after 50 20031201 |
| Low incidence of cytomegalovirus disease in liver transplant recipients receiving sirolimus primary immunosuppression with 3-day corticosteroid taper. | Transplant infectious disease : an official journal of the Transplantation Society 20031201 |
| Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E. | The Journal of biological chemistry 20031128 |
| [Are drug-coated stents too expensive?]. | Deutsche medizinische Wochenschrift (1946) 20031121 |
| Atrophic remodeling of the heart in vivo simultaneously activates pathways of protein synthesis and degradation. | Circulation 20031118 |
| Chromatin-mediated regulation of nucleolar structure and RNA Pol I localization by TOR. | The EMBO journal 20031117 |
| Immediate response of mammalian target of rapamycin (mTOR)-mediated signalling following acute resistance exercise in rat skeletal muscle. | The Journal of physiology 20031115 |
| Control of nutrient-sensitive transcription programs by the unconventional prefoldin URI. | Science (New York, N.Y.) 20031114 |
| Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation. | American journal of physiology. Endocrinology and metabolism 20031101 |
| Characterization of the transport of the bicyclic peptide phalloidin by human hepatic transport proteins. | Naunyn-Schmiedeberg's archives of pharmacology 20031101 |
| Rapamycin antagonizes cyclosporin A- and tacrolimus (FK506)-mediated augmentation of linker for activation of T cell expression in T cells. | International immunology 20031101 |
| Sirolimus-induced interstitial pneumonitis in an islet transplant recipient. | Diabetes care 20031101 |
| Rapamycin has a deleterious effect on MIN-6 cells and rat and human islets. | Diabetes 20031101 |
| Macrophage colony-stimulating factor-dependent macrophage proliferation is mediated through a calcineurin-independent but immunophilin-dependent mechanism that mediates the activation of external regulated kinases. | European journal of immunology 20031101 |
| Design and structure-based study of new potential FKBP12 inhibitors. | Biophysical journal 20031101 |
| Angiographic regression of cardiac allograft vasculopathy after introducing sirolimus immunosuppression. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20031101 |
| Multi-lesion culotte and crush bifurcation stenting with sirolimus-eluting stents: long-term angiographic outcome. | The Journal of invasive cardiology 20031101 |
| Low-dose sirolimus in combination with mycophenolate in calcineurin inhibitor elimination: the Kuwaiti experience. | Transplantation proceedings 20031101 |
| Induction of protein synthesis in cardiac fibroblasts by cardiotrophin-1: integration of multiple signaling pathways. | Cardiovascular research 20031101 |
| The role of nitrate reductase in the regulation of the nitrate assimilation pathway in the yeast Hansenula polymorpha. | FEMS yeast research 20031101 |
| Determination of the pharmacokinetics of cerivastatin when administered in combination with sirolimus and cyclosporin A in patients with kidney transplant, and review of the relevant literature. | International journal of clinical pharmacology and therapeutics 20031101 |
| Drug-eluting stents in peripheral vascular disease: eliminating restenosis. | The Mount Sinai journal of medicine, New York 20031101 |
| Will mTOR inhibitors make it as cancer drugs? | Cancer cell 20031101 |
| Immunosuppression in renal transplantation: where are we now? | Hospital medicine (London, England : 1998) 20031101 |
| Bibliography. Current world literature. Therapeutic modalities. | Current opinion in oncology 20031101 |
| Differential effect of cyclosporine A and SDZ RAD on neointima formation of carotid allografts in apolipoprotein E-deficient mice. | Transplantation 20031027 |
| Sirolimus-eluting stent implantation in ST-elevation acute myocardial infarction: a clinical and angiographic study. | Circulation 20031021 |
| Target of rapamycin (TOR)-signaling and RAIP motifs play distinct roles in the mammalian TOR-dependent phosphorylation of initiation factor 4E-binding protein 1. | The Journal of biological chemistry 20031017 |
| Drug-eluting stents substantially lower rate of restenosis. | Report on medical guidelines & outcomes research 20031017 |
| Insulin independence after conversion to tacrolimus and sirolimus-based immunosuppression in islet-kidney recipients. | Transplantation 20031015 |
| Involvement of the VDE homing endonuclease and rapamycin in regulation of the Saccharomyces cerevisiae GSH11 gene encoding the high affinity glutathione transporter. | The Journal of biological chemistry 20031010 |
| Drug-delivering coronary artery stents: bare metal threatened by extinction? | Lancet (London, England) 20031004 |
| Sirolimus-eluting stents for treatment of patients with long atherosclerotic lesions in small coronary arteries: double-blind, randomised controlled trial (E-SIRIUS). | Lancet (London, England) 20031004 |
| Insulin-like growth factor-I inhibits transcriptional responses of transforming growth factor-beta by phosphatidylinositol 3-kinase/Akt-dependent suppression of the activation of Smad3 but not Smad2. | The Journal of biological chemistry 20031003 |
| Sirolimus for the prevention of in-stent restenosis in a coronary artery. | The New England journal of medicine 20031002 |
| Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery. | The New England journal of medicine 20031002 |
| Beta-adrenergic agonists regulate Na-K-ATPase via p70S6k. | American journal of physiology. Lung cellular and molecular physiology 20031001 |
| Amino acid transport regulates blastocyst implantation. | Biology of reproduction 20031001 |
| Rapamycin-based rescue therapy after chronic rejection in a pediatric liver transplant patient. | Transplant international : official journal of the European Society for Organ Transplantation 20031001 |
| Tissue-specific regulation of protein synthesis by insulin and free fatty acids. | American journal of physiology. Endocrinology and metabolism 20031001 |
| Cytokines regulate the pattern of rejection and susceptibility to cyclosporine therapy in different mouse recipient strains after cardiac allografting. | Journal of immunology (Baltimore, Md. : 1950) 20031001 |
| M-CSF, TNFalpha and RANK ligand promote osteoclast survival by signaling through mTOR/S6 kinase. | Cell death and differentiation 20031001 |
| Fc-dependent depletion of activated T cells occurs through CD40L-specific antibody rather than costimulation blockade. | Nature medicine 20031001 |
| Determination of sirolimus blood concentration using high-performance liquid chromatography with ultraviolet detection. | Therapeutic drug monitoring 20031001 |
| Pharmacokinetic interactions between sirolimus and microemulsion cyclosporine when orally administered jointly and 4 hours apart in healthy volunteers. | Journal of clinical pharmacology 20031001 |
| Pilot study of oral rapamycin to prevent restenosis in patients undergoing coronary stent therapy: Argentina Single-Center Study (ORAR Trial). | The Journal of invasive cardiology 20031001 |
| [Non cardiac surgery in patient with coronary stenting: think sirolimus now!]. | Annales francaises d'anesthesie et de reanimation 20031001 |
| Renal function improves in liver transplant recipients when switched from a calcineurin inhibitor to sirolimus. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20031001 |
| Negative regulation of interleukin-12 production by a rapamycin-sensitive signaling pathway: a brief communication. | Experimental biology and medicine (Maywood, N.J.) 20031001 |
| Rapamycin preserves renal function compared with cyclosporine A after ischemia/reperfusion injury. | Urology 20031001 |
| Everolimus in de novo cardiac transplantation: pharmacokinetics, therapeutic range, and influence on cyclosporine exposure. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20031001 |
| Sirolimus-eluting stents for the treatment of in-stent restenosis. | Minerva cardioangiologica 20031001 |
| Evolving standard in the treatment of coronary artery disease. Drug-eluting stents. | Minerva cardioangiologica 20031001 |
| Using intravascular ultrasound with drug-eluting stents. What have we learned so far? | Minerva cardioangiologica 20031001 |
| Attachment of the ubiquitin-related protein Urm1p to the antioxidant protein Ahp1p. | Eukaryotic cell 20031001 |
| Excellent short-term results with steroid-free maintenance immunosuppression in low-risk simultaneous pancreas-kidney transplantation. | Archives of surgery (Chicago, Ill. : 1960) 20031001 |
| The PCPH oncoprotein antagonizes the proapoptotic role of the mammalian target of rapamycin in the response of normal fibroblasts to ionizing radiation. | Cancer research 20031001 |
| Drug-eluting stents and glycoprotein IIb/IIIa inhibitors: combination therapy for the future. | American heart journal 20031001 |
| Posterior leukoencephalopathy with cyclosporine. | Clinical nephrology 20031001 |
| Immunosuppression in liver transplantation. | Minerva chirurgica 20031001 |
| [Perspectives of pharmacological anti-proliferative therapy for arteriosclerosis]. | Recenti progressi in medicina 20031001 |
| Drug-eluting versus bare metal coronary stents: long-term human pathology. Findings from different coronary arteries in the same patient. | Italian heart journal : official journal of the Italian Federation of Cardiology 20031001 |
| Withdrawal of steroid therapy in African American kidney transplant recipients receiving sirolimus and tacrolimus. | Transplantation 20030927 |
| Tor1/2 regulation of retrograde gene expression in Saccharomyces cerevisiae derives indirectly as a consequence of alterations in ammonia metabolism. | The Journal of biological chemistry 20030919 |
| Anti-third-party veto CTLs overcome rejection of hematopoietic allografts: synergism with rapamycin and BM cell dose. | Blood 20030915 |
| Rapamycin-induced oligospermia. | Transplantation 20030915 |
| Bcr-Abl kinase modulates the translation regulators ribosomal protein S6 and 4E-BP1 in chronic myelogenous leukemia cells via the mammalian target of rapamycin. | Cancer research 20030915 |
| Mitogenic effect of glial cell line-derived neurotrophic factor is dependent on the activation of p70S6 kinase, but independent of the activation of ERK and up-regulation of Ret in SH-SY5Y cells. | Brain research 20030905 |
| Conditional protein splicing: a new tool to control protein structure and function in vitro and in vivo. | Journal of the American Chemical Society 20030903 |
| Rapamycin causes down-regulation of CCR5 and accumulation of anti-HIV beta-chemokines: an approach to suppress R5 strains of HIV-1. | Proceedings of the National Academy of Sciences of the United States of America 20030902 |
| Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation. | Blood 20030901 |
| Drosophila Rheb GTPase is required for cell cycle progression and cell growth. | Journal of cell science 20030901 |
| Comparison of sirolimus vs. mycophenolate mofetil on surgical complications and wound healing in adult kidney transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030901 |
| Oral rapamycin in the treatment of diffuse proliferative in-stent restenosis in a patient with small reference vessel. | The Journal of invasive cardiology 20030901 |
| Involvement of the Akt/mTOR pathway on EGF-induced cell transformation. | Molecular carcinogenesis 20030901 |
| The long-term survival of baboon-to-monkey kidney and liver xenografts. | Xenotransplantation 20030901 |
| Parallel purification of three catalytic subunits of the protein serine/threonine phosphatase 2A family (PP2A(C), PP4(C), and PP6(C)) and analysis of the interaction of PP2A(C) with alpha4 protein. | Protein expression and purification 20030901 |
| Second window of protection following myocardial preconditioning: an essential role for PI3 kinase and p70S6 kinase. | Journal of molecular and cellular cardiology 20030901 |
| Rapamycin treatment at immunosuppressive doses affects tumor blood vessel circulation. | Transplantation proceedings 20030901 |
| Rapamycin in children after liver transplantation. | Transplantation proceedings 20030901 |
| Pathologic assessment of cardiomyocytes in heart transplant recipients treated with rapamycin or cyclosporine. | Transplantation proceedings 20030901 |
| Deterioration of renal function after replacement of cyclosporine with sirolimus in five patients with severe renal impairment late after heart transplantation. | Transplantation proceedings 20030901 |
| Restenosis in percutaneous coronary intervention--is drug-eluting stent the answer? | Singapore medical journal 20030901 |
| Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner. | The Journal of biological chemistry 20030829 |
| Rapamycin inhibits GM-CSF-induced neutrophil migration. | FEBS letters 20030828 |
| Cardiac-allograft vasculopathy. | The New England journal of medicine 20030828 |
| Everolimus for the prevention of allograft rejection and vasculopathy in cardiac-transplant recipients. | The New England journal of medicine 20030828 |
| LF 15-0195, a novel immunosuppressive agent prevents rejection and induces operational tolerance in a mouse cardiac allograft model. | Transplantation 20030827 |
| Muscarinic receptor-mediated activation of p70 S6 kinase 1 (S6K1) in 1321N1 astrocytoma cells: permissive role of phosphoinositide 3-kinase. | The Biochemical journal 20030815 |
| Synergistic effects of CTLA-4Ig and sirolimus on orthotopic lung-allograft survival and histology. | Transplantation 20030815 |
| Apoptosis and treatment of chronic allograft nephropathy with everolimus. | Transplantation 20030815 |
| Successful infliximab treatment of steroid and OKT3 refractory acute cellular rejection in two patients after intestinal transplantation. | Transplantation 20030815 |
| Chronic myeloid leukemia: pathophysiology, diagnostic parameters, and current treatment concepts. | Wiener klinische Wochenschrift 20030814 |
| CYPHER coronary stents and risk of thrombosis. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030805 |
| Survival of acute myeloid leukemia cells requires PI3 kinase activation. | Blood 20030801 |
| Intestinal sugar absorption is regulated by phosphorylation and turnover of protein kinase C betaII mediated by phosphatidylinositol 3-kinase- and mammalian target of rapamycin-dependent pathways. | The Journal of biological chemistry 20030801 |
| Divergence in signaling pathways involved in promotion of cell viability mediated by bFGF, NGF, and EGF in PC12 cells. | Neurochemical research 20030801 |
| The serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitor. | Genes & development 20030801 |
| Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. | Genes & development 20030801 |
| The phosphatidylinositol-3 kinase (PI3K)-Akt pathway suppresses neurite branch formation in NGF-treated PC12 cells. | Genes to cells : devoted to molecular & cellular mechanisms 20030801 |
| Long-term pharmacokinetic study of the novel combination of tacrolimus and sirolimus in de novo renal allograft recipients. | Therapeutic drug monitoring 20030801 |
| Effectiveness of sirolimus-eluting stent for treatment of left main coronary artery disease. | The American journal of cardiology 20030801 |
| Effects of FK506 and rapamycin on generation of reactive oxygen species, nitric oxide production and nuclear factor kappa B activation in rat hepatocytes. | Biochemical pharmacology 20030801 |
| Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas. | Cancer research 20030801 |
| Immunophilins, mTOR, and pharmacodynamic strategies for a targeted cancer therapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
| Pharmacodynamic Evaluation of CCI-779, an Inhibitor of mTOR, in Cancer Patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
| Rapamycin-sensitive signalling in long-term consolidation of auditory cortex-dependent memory. | The European journal of neuroscience 20030801 |
| Postgrafting immunosuppression with sirolimus and cyclosporine facilitates stable mixed hematopoietic chimerism in dogs given sublethal total body irradiation before marrow transplantation from DLA-identical littermates. | Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 20030801 |
| Rapamycin inhibits telomerase activity by decreasing the hTERT mRNA level in endometrial cancer cells. | Molecular cancer therapeutics 20030801 |
| Treatment of idiopathic nephrosis by immunophillin modulation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030801 |
| TSC2 regulates VEGF through mTOR-dependent and -independent pathways. | Cancer cell 20030801 |
| Early elimination of cyclosporine in kidney transplant recipients receiving sirolimus prevents progression of chronic pathologic allograft lesions. | Transplantation proceedings 20030801 |
| Defining the initial doses of sirolimus and tacrolimus in the period immediately after renal transplantation. | Transplantation proceedings 20030801 |
| Rapamycin in lung transplantation: preliminary results. | Transplantation proceedings 20030801 |
| Sirolimus in heart transplantation: a single center initial experience. | Transplantation proceedings 20030801 |
| Integration of growth factor and nutrient signaling: implications for cancer biology. | Molecular cell 20030801 |
| Retrograde signaling is regulated by the dynamic interaction between Rtg2p and Mks1p. | Molecular cell 20030801 |
| Sirolimus-induced interstitial pneumonitis in a renal transplant recipient. | Journal of the Formosan Medical Association = Taiwan yi zhi 20030801 |
| Sirolimus does not increase the risk for postoperative thromboembolic events among renal transplant recipients. | Transplantation 20030727 |
| Long-term improvement in renal function with sirolimus after early cyclosporine withdrawal in renal transplant recipients: 2-year results of the Rapamune Maintenance Regimen Study. | Transplantation 20030727 |
| Dyslipidemia in renal transplant recipients treated with a sirolimus and cyclosporine-based immunosuppressive regimen: incidence, risk factors, progression, and prognosis. | Transplantation 20030727 |
| Higher surgical wound complication rates with sirolimus immunosuppression after kidney transplantation: a matched-pair pilot study. | Transplantation 20030727 |
| Mechanism of ribosomal p70S6 kinase activation by granulocyte macrophage colony-stimulating factor in neutrophils: cooperation of a MEK-related, THR421/SER424 kinase and a rapamycin-sensitive, m-TOR-related THR389 kinase. | The Journal of biological chemistry 20030725 |
| Coronary restenosis after sirolimus-eluting stent implantation: morphological description and mechanistic analysis from a consecutive series of cases. | Circulation 20030722 |
| Restenosis: the mouse that roared. | Circulation 20030722 |
| Modulation of translation-initiation in CHO-K1 cells by rapamycin-induced heterodimerization of engineered eIF4G fusion proteins. | Biotechnology and bioengineering 20030720 |
| Hyperosmotic stress inhibits insulin receptor substrate-1 function by distinct mechanisms in 3T3-L1 adipocytes. | The Journal of biological chemistry 20030718 |
| Mutational analysis of ribosomal S6 kinase 2 shows differential regulation of its kinase activity from that of ribosomal S6 kinase 1. | The Biochemical journal 20030715 |
| Ca(2+)-independent protein kinase C activity is required for alpha1-adrenergic-receptor-mediated regulation of ribosomal protein S6 kinases in adult cardiomyocytes. | The Biochemical journal 20030715 |
| Effectiveness of sirolimus-eluting stent implantation for recurrent in-stent restenosis after brachytherapy. | The American journal of cardiology 20030715 |
| Rabbit antithymocyte globulin induction and sirolimus monotherapy supports prolonged islet allograft function in a nonhuman primate islet transplantation model. | Transplantation 20030715 |
| Novel sulfur-containing rapamycin analogs prepared by precursor-directed biosynthesis. | Organic letters 20030710 |
| Differential translation of TOP mRNAs in rapamycin-treated human B lymphocytes. | Biochimica et biophysica acta 20030709 |
| Use of rapamycin slows progression of cardiac transplantation vasculopathy. | Circulation 20030708 |
| Rapamycin for cardiac transplant rejection and vasculopathy: one stone, two birds? | Circulation 20030708 |
| Rapamycin slows heart transplant vasculopathy. | Circulation 20030708 |
| Alpha-Synuclein is degraded by both autophagy and the proteasome. | The Journal of biological chemistry 20030704 |
| Sirolimus and mycophenolate mofetil after liver transplantation. | Transplant international : official journal of the European Society for Organ Transplantation 20030701 |
| Effects of cyclosporin A and a rapamycin derivative (SAR943) on chronic allergic inflammation in sensitized rats. | Immunology 20030701 |
| The role of c-Myc on granulocyte colony-stimulating factor-dependent neutrophilic proliferation and differentiation of HL-60 cells. | Biochemical pharmacology 20030701 |
| Angiotensin II induces connective tissue growth factor gene expression via calcineurin-dependent pathways. | The American journal of pathology 20030701 |
| Interstitial granulomatous pneumonitis associated with sirolimus in a child after liver transplantation. | Journal of pediatric gastroenterology and nutrition 20030701 |
| Effects of immunomodulators on airways hyperresponsiveness to adenosine induced in actively sensitised Brown Norway rats by exposure to allergen. | Naunyn-Schmiedeberg's archives of pharmacology 20030701 |
| Sirolimus-induced thrombotic microangiopathy in a renal transplant recipient. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20030701 |
| The influence of the rapamycin-derivate SDZ RAD on the healing of airway anastomoses. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20030701 |
| 'Cyclosporine-sparing' regimen approved. | The American journal of nursing 20030701 |
| [Position paper on the use of drug eluting stents (DES) in percutaneous coronary interventions in patients with coronary heart disease]. | Zeitschrift fur Kardiologie 20030701 |
| Mutant type glutathione S-transferase theta 1 gene homologue to mTOR in myelodysplastic syndrome: possible clinical application of rapamycin. | Leukemia & lymphoma 20030701 |
| New stents, hopes--and questions. After approval of a drug-coated cylinder, patients face wider options. | Heart advisor 20030701 |
| High-throughput liquid chromatography-tandem mass spectrometric analysis of sirolimus in whole blood. | Clinical chemistry and laboratory medicine 20030701 |
| mTOR inhibitors in hematologic malignancies. | Clinical advances in hematology & oncology : H&O 20030701 |
| A prospective randomized multicenter study of tacrolimus in combination with sirolimus in renal-transplant recipients. | Transplantation 20030627 |
| Everolimus in pediatric de nova renal transplant patients. | Transplantation 20030627 |
| Treatment with humanized monoclonal antibodies against CD80 and CD86 combined with sirolimus prolongs renal allograft survival in cynomolgus monkeys. | Transplantation 20030627 |
| Primary intestinal posttransplant T-cell lymphoma. | Transplantation 20030627 |
| Phospholipase D confers rapamycin resistance in human breast cancer cells. | Oncogene 20030619 |
| Induction of apoptosis in IL-3-dependent hematopoietic cell lines by guanine nucleotide depletion. | Blood 20030615 |
| Proliferation and survival of activated B cells requires sustained antigen receptor engagement and phosphoinositide 3-kinase activation. | Journal of immunology (Baltimore, Md. : 1950) 20030615 |
| Pharmacologically regulated production of targeted retrovirus from T cells for systemic antitumor gene therapy. | Cancer research 20030615 |
| Long-term islet allograft survival in nonobese diabetic mice treated with tacrolimus, rapamycin, and anti-interleukin-2 antibody. | Transplantation 20030615 |
| First drug-eluting coronary stent approved. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030615 |
| Regulation of the phosphatidylinositol 3-kinase, Akt/protein kinase B, FRAP/mammalian target of rapamycin, and ribosomal S6 kinase 1 signaling pathways by thyroid-stimulating hormone (TSH) and stimulating type TSH receptor antibodies in the thyroid gland. | The Journal of biological chemistry 20030613 |
| Rapamycin-induced translational derepression of GCN4 mRNA involves a novel mechanism for activation of the eIF2 alpha kinase GCN2. | The Journal of biological chemistry 20030606 |
| Early outcome after sirolimus-eluting stent implantation in patients with acute coronary syndromes: insights from the Rapamycin-Eluting Stent Evaluated At Rotterdam Cardiology Hospital (RESEARCH) registry. | Journal of the American College of Cardiology 20030604 |
| Rapamycin inhibits IL-4--induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo. | Blood 20030601 |
| Regulation of targets of mTOR (mammalian target of rapamycin) signalling by intracellular amino acid availability. | The Biochemical journal 20030601 |
| p38 MAP kinase regulates BMP-4-stimulated VEGF synthesis via p70 S6 kinase in osteoblasts. | American journal of physiology. Endocrinology and metabolism 20030601 |
| Campath-1H induction plus rapamycin monotherapy for renal transplantation: results of a pilot study. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030601 |
| Influence of SDZ RAD vs. MMF on gastric emptying in renal transplant recipients. | Clinical transplantation 20030601 |
| Single HSV-amplicon vector mediates drug-induced gene expression via dimerizer system. | Molecular therapy : the journal of the American Society of Gene Therapy 20030601 |
| The evolving role of sirolimus in renal transplantation. | QJM : monthly journal of the Association of Physicians 20030601 |
| Phase I and pharmacokinetic study of CCI-779, a novel cytostatic cell-cycle inhibitor, in combination with 5-fluorouracil and leucovorin in patients with advanced solid tumors. | Annals of oncology : official journal of the European Society for Medical Oncology 20030601 |
| Rapamycin treatment results in GATA factor-independent hyperphosphorylation of the proline utilization pathway activator in Saccharomyces cerevisiae. | Eukaryotic cell 20030601 |
| Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake. | Metabolism: clinical and experimental 20030601 |
| Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast. | Molecular cell 20030601 |
| Sustained activation of the JNK cascade and rapamycin-induced apoptosis are suppressed by p53/p21(Cip1). | Molecular cell 20030601 |
| The rush is on to acquire drug-eluting stents. | Hospital material[dollar sign] management 20030601 |
| Rapid conversion to sirolimus for chronic progressive deterioration of the renal function in kidney allograft recipients. | Transplantation proceedings 20030601 |
| Opening the shut cases. Drug-coated stents may solve the biggest problem with angioplasty--keeping coronary arteries open. | Harvard health letter 20030601 |
| In vitro immunomodulatory activity of ruthenium complexes. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030601 |
| Mammalian target of rapamycin: a new molecular target for breast cancer. | Clinical breast cancer 20030601 |
| [Drug-eluting stents in complex lesions]. | Annales de cardiologie et d'angeiologie 20030601 |
| [In-stent restenosis: which indications for drug-eluting stent?]. | Annales de cardiologie et d'angeiologie 20030601 |
| Sirolimus: a current perspective. | Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation 20030601 |
| Immunosuppressive TOR kinase inhibitor everolimus (RAD) suppresses growth of cells derived from posttransplant lymphoproliferative disorder at allograft-protecting doses. | Transplantation 20030527 |
| Synergistic immunosuppressive effects of rosmarinic acid and rapamycin in vitro and in vivo. | Transplantation 20030527 |
| ERK and p38 inhibit the expression of 4E-BP1 repressor of translation through induction of Egr-1. | The Journal of biological chemistry 20030523 |
| Insulin induces expression of adenosine kinase gene in rat lymphocytes by signaling through the mitogen-activated protein kinase pathway. | Experimental cell research 20030515 |
| Airway anastomotic dehiscence associated with use of sirolimus immediately after lung transplantation. | Transplantation 20030515 |
| Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis. | Transplantation 20030515 |
| Sirolimus (rapamycin) monotherapy prevents graft vascular disease in nonhuman primate recipients of orthotopic aortic allografts. | Circulation 20030513 |
| Domains of Gln3p interacting with karyopherins, Ure2p, and the target of rapamycin protein. | The Journal of biological chemistry 20030509 |
| Preliminary observations regarding angiographic pattern of restenosis after rapamycin-eluting stent implantation. | Circulation 20030506 |
| Critical role for PI 3-kinase in the control of erythropoietin-induced erythroid progenitor proliferation. | Blood 20030501 |
| Estradiol rapidly activates Akt via the ErbB2 signaling pathway. | Molecular endocrinology (Baltimore, Md.) 20030501 |
| Involvement of S6 kinase and p38 mitogen activated protein kinase pathways in strain-induced alignment and proliferation of bovine aortic smooth muscle cells. | Journal of cellular physiology 20030501 |
| Transplant immunosuppressant agents and their role in autoimmune rheumatic diseases. | Current opinion in rheumatology 20030501 |
| Evaluation of coronary remodeling after sirolimus-eluting stent implantation by serial three-dimensional intravascular ultrasound. | The American journal of cardiology 20030501 |
| Pharmacokinetics of tacrolimus-based combination therapies. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030501 |
| Sirolimus as primary immunosuppression in liver transplantation is not associated with hepatic artery or wound complications. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030501 |
| Rapamycin: friend, foe, or misunderstood? | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030501 |
| A retrospective review of sirolimus (Rapamune) therapy in orthotopic liver transplant recipients diagnosed with chronic rejection. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030501 |
| TOR inhibitors and cardiac allograft vasculopathy: is inhibition of intimal thickening an adequate surrogate of benefit? | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030501 |
| Rapamycin inhibits vascular remodeling in an experimental model of allograft vasculopathy and attenuates associated changes in fibrosis-associated gene expression. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030501 |
| Sirolimus: its discovery, biological properties, and mechanism of action. | Transplantation proceedings 20030501 |
| The development of immunosuppression: the rapamycin milestone. | Transplantation proceedings 20030501 |
| The Rapamune era of immunosuppression 2003: the journey from the laboratory to clinical transplantation. | Transplantation proceedings 20030501 |
| Ten years of sirolimus therapy for human renal transplantation: the University of Texas at Houston experience. | Transplantation proceedings 20030501 |
| Sirolimus therapy without calcineurin inhibitors: Necker Hospital 8-year experience. | Transplantation proceedings 20030501 |
| Bicêtre hospital experience with sirolimus-based therapy in human renal transplantation: the Sirolimus European Renal Transplant Study. | Transplantation proceedings 20030501 |
| Design of a trial comparing sirolimus plus mycophenolate mofetil versus sirolimus plus cyclosporine. | Transplantation proceedings 20030501 |
| Optimizing the long-term outcome of renal transplants: opportunities created by sirolimus. | Transplantation proceedings 20030501 |
| Use of sirolimus to facilitate cyclosporine avoidance or steroid withdrawal in kidney transplant recipients. | Transplantation proceedings 20030501 |
| How should sirolimus be used in clinical practice? | Transplantation proceedings 20030501 |
| Sirolimus experience at a Swedish transplantation center. | Transplantation proceedings 20030501 |
| Sirolimus in combination with tacrolimus or mycophenolate mofetil for minimizing acute rejection risk in renal transplant recipients--a single center experience. | Transplantation proceedings 20030501 |
| Sirolimus-based immunosuppression with reduce dose cyclosporine or tacrolimus after renal transplantation. | Transplantation proceedings 20030501 |
| Sirolimus: a single center experience in combination with calcineurin inhibitors. | Transplantation proceedings 20030501 |
| Observations on the use of sirolimus and tacrolimus in high-risk renal transplant recipients. | Transplantation proceedings 20030501 |
| Sirolimus immunotherapy: the Albany Medical Center experience. | Transplantation proceedings 20030501 |
| Sirolimus in pediatric transplant recipients. | Transplantation proceedings 20030501 |
| Reduced and standard target concentration tacrolimus with sirolimus in renal allograft recipients. | Transplantation proceedings 20030501 |
| Minimizing calcineurin inhibitor drugs in renal transplantation. | Transplantation proceedings 20030501 |
| Fixed-dose sirolimus with reduced dose calcineurin inhibitor: the University of Colorado experience. | Transplantation proceedings 20030501 |
| Kidney transplantation without calcineurin inhibitors using sirolimus. | Transplantation proceedings 20030501 |
| Sirolimus monotherapy following Campath-1H induction. | Transplantation proceedings 20030501 |
| Conversion to sirolimus in solid organ transplantation: a single-center experience. | Transplantation proceedings 20030501 |
| Clinical use of rapamycin in renal allograft recipients identifies its relevant toxicity profile and raises unsolved questions: a single-center experience. | Transplantation proceedings 20030501 |
| Sirolimus changes lipid concentrations and lipoprotein metabolism in kidney transplant recipients. | Transplantation proceedings 20030501 |
| Cardiovascular risk factors of sirolimus compared with cyclosporine: early experience from two randomized trials in renal transplantation. | Transplantation proceedings 20030501 |
| Tubular function in patients with hypokalemia induced by sirolimus after renal transplantation. | Transplantation proceedings 20030501 |
| Therapeutic monitoring of sirolimus: its contribution to optimal prescription. | Transplantation proceedings 20030501 |
| Use of rapamycin-impregnated stents in coronary arteries. | Transplantation proceedings 20030501 |
| Sirolimus therapy in cardiac transplantation. | Transplantation proceedings 20030501 |
| Safety and efficacy of sirolimus in kidney transplant patients and in patients with coronary artery disease undergoing angioplasty. | Transplantation proceedings 20030501 |
| De novo use of sirolimus in immunosuppression regimens in kidney and kidney-pancreas transplantation at the University of California, San Francisco. | Transplantation proceedings 20030501 |
| Sirolimus and islet transplants. | Transplantation proceedings 20030501 |
| Sirolimus in liver transplantation. | Transplantation proceedings 20030501 |
| Rapamycin in combination with cyclosporine or tacrolimus in liver, pancreas, and kidney transplantation. | Transplantation proceedings 20030501 |
| Ten years of sirolimus therapy in orthotopic liver transplant recipients. | Transplantation proceedings 20030501 |
| Preclinical results of sirolimus treatment in transplant models. | Transplantation proceedings 20030501 |
| Molecular actions of sirolimus: sirolimus and mTor. | Transplantation proceedings 20030501 |
| Rapamycin: signaling in vascular smooth muscle. | Transplantation proceedings 20030501 |
| Protective effect of the immunosuppressant sirolimus against aortic atherosclerosis in apo E-deficient mice. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030501 |
| Pharmacokinetics of an everolimus-cyclosporine immunosuppressive regimen over the first 6 months after kidney transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030501 |
| The effect of combined rapamycin/cyclosporine on the changes in pro-fibrotic gene expression that occur during the development of allograft vasculopathy in rats, compared with cyclosporine or rapamycin in isolation. | Transplant international : official journal of the European Society for Organ Transplantation 20030501 |
| Rapamycin throws a master switch. | Environmental health perspectives 20030501 |
| Clinical experience of sirolimus-eluting stents in patients with coronary artery disease at Bangkok Heart Institute. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20030501 |
| CD45RB-targeting strategies for promoting long-term allograft survival and preventingchronic allograft vasculopathy. | Transplantation 20030427 |
| Randomized trial of tacrolimus in combination with sirolimus or mycophenolate mofetil in kidney transplantation: results at 6 months. | Transplantation 20030427 |
| Health-related quality-of-life outcomes of sirolimus-treated kidney transplant patients after elimination of cyclosporine A: results of a 2-year randomized clinical trial. | Transplantation 20030427 |
| Thymoglobulin, sirolimus, and reduced-dose cyclosporine provides excellent rejection prophylaxis for pancreas transplantation. | Transplantation 20030427 |
| A phase III prospective, randomized study to evaluate concentration-controlled sirolimus (rapamune) with cyclosporine dose minimization or elimination at six months in de novo renal allograft recipients. | Transplantation 20030427 |
| Mutation in TSC2 and activation of mammalian target of rapamycin signalling pathway in renal angiomyolipoma. | Lancet (London, England) 20030419 |
| Downstream effectors of oncogenic ras in multiple myeloma cells. | Blood 20030415 |
| Inhibition of phosphatidylinositol 3-kinase and p70S6 kinase blocks osteogenic protein-1 induction of alkaline phosphatase activity in fetal rat calvaria cells. | Journal of cellular biochemistry 20030415 |
| Early withdrawal of cyclosporine A improves 1-year kidney graft structure and function in sirolimus-treated patients. | Transplantation 20030415 |
| Effect of immunosuppressants on T-cell subsets observed in vivo using carboxy-fluorescein diacetate succinimidyl ester labeling. | Transplantation 20030415 |
| Amino acid availability regulates S6K1 and protein synthesis in avian insulin-insensitive QM7 myoblasts. | FEBS letters 20030410 |
| Pilot trial of oral rapamycin for recalcitrant restenosis. | Circulation 20030408 |
| Insulin-like growth factor-I inhibits progesterone receptor expression in breast cancer cells via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin pathway: progesterone receptor as a potential indicator of growth factor activity in breast cancer. | Molecular endocrinology (Baltimore, Md.) 20030401 |
| Translational control by TOR and TAP42 through dephosphorylation of eIF2alpha kinase GCN2. | Genes & development 20030401 |
| Delayed graft function and cast nephropathy associated with tacrolimus plus rapamycin use. | Journal of the American Society of Nephrology : JASN 20030401 |
| Rapamycin attenuates load-induced cardiac hypertrophy in mice. | Circulation 20030401 |
| Rapamycin mimics the incompatibility reaction in the fungus Podospora anserina. | Eukaryotic cell 20030401 |
| Sirolimus delays renal allograft recovery. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030401 |
| Sirolimus prolongs recovery from delayed graft function after cadaveric renal transplantation. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030401 |
| The addition of sirolimus to cyclosporine and steroids inhibits the anti-equine antibody response in renal transplant recipients treated with antithymocyte globulin. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030401 |
| GbetaL, a positive regulator of the rapamycin-sensitive pathway required for the nutrient-sensitive interaction between raptor and mTOR. | Molecular cell 20030401 |
| Regulated expression of erythropoietin from an AAV vector safely improves the anemia of beta-thalassemia in a mouse model. | Molecular therapy : the journal of the American Society of Gene Therapy 20030401 |
| [Coronary stents]. | Therapeutische Umschau. Revue therapeutique 20030401 |
| [Prevention of postangioplasty restenosis]. | Nihon rinsho. Japanese journal of clinical medicine 20030401 |
| Through the drug-eluting stent labyrinth. | Italian heart journal : official journal of the Italian Federation of Cardiology 20030401 |
| Coronary angioplasty--have we conquered restenosis? | Journal of the Indian Medical Association 20030401 |
| [Effect of rapamycin on NF-kappaB induction]. | The Japanese journal of antibiotics 20030401 |
| [Influence of erythromycin and the metabolite, EM201 on IL-2 receptor signaling]. | The Japanese journal of antibiotics 20030401 |
| [Suppressive effect of spiramycin on cell division]. | The Japanese journal of antibiotics 20030401 |
| Branched-chain amino acids promote albumin synthesis in rat primary hepatocytes through the mTOR signal transduction system. | Biochemical and biophysical research communications 20030328 |
| Rapamycin inhibits E2F-dependent expression of minichromosome maintenance proteins in vascular smooth muscle cells. | Biochemical and biophysical research communications 20030328 |
| The impact of cyclosporine dose reduction with or without the addition of rapamycin on functional, molecular, and histological markers of chronic allograft nephropathy. | Transplantation 20030327 |
| Oral ulcers in kidney transplant recipients treated with sirolimus and mycophenolate mofetil. | Transplantation 20030327 |
| New immunosuppressive agent: expectations and controversies. | Transplantation 20030327 |
| Rapamycin inhibits proliferation of human neuroblastoma cells without suppression of MycN. | International journal of cancer 20030320 |
| Drug-eluting stents. | The Medical letter on drugs and therapeutics 20030317 |
| eIF4E/4E-BP dissociation and 4E-BP degradation in the first mitotic division of the sea urchin embryo. | Developmental biology 20030315 |
| Kidney transplantation with rabbit antithymocyte globulin and sirolimus monotherapy. | Lancet (London, England) 20030315 |
| Images in cardiovascular medicine. Sirolimus-eluting stent implanted in human coronary artery for 16 months: pathological findings. | Circulation 20030311 |
| Energetic and structural analysis of the role of tryptophan 59 in FKBP12. | Biochemistry 20030304 |
| Selective, stable demethylation of the interleukin-2 gene enhances transcription by an active process. | Nature immunology 20030301 |
| Kidney function and morphology after short-term combination therapy with cyclosporine A, tacrolimus and sirolimus in the rat. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030301 |
| Studies investigating pretransplant donor-specific blood transfusion, rapamycin, and the CD154-specific antibody IDEC-131 in a nonhuman primate model of skin allotransplantation. | Journal of immunology (Baltimore, Md. : 1950) 20030301 |
| Macrophage labeling by SPIO as an early marker of allograft chronic rejection in a rat model of kidney transplantation. | Magnetic resonance in medicine 20030301 |
| Rapamycin in cardiovascular medicine. | Internal medicine journal 20030301 |
| Thrombotic micro-angiopathy with sirolimus-based immunosuppression: potentiation of calcineurin-inhibitor-induced endothelial damage? | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030301 |
| Rapamycin is an effective inhibitor of human renal cancer metastasis. | Kidney international 20030301 |
| Drug-eluting stents: potential applications for peripheral arterial occlusive disease. | Journal of vascular and interventional radiology : JVIR 20030301 |
| Comment: delayed wound healing with sirolimus after liver transplant. | The Annals of pharmacotherapy 20030301 |
| Rapamycin use and rapid withdrawal of calcineurin inhibitors in pediatric renal transplantation. | Transplantation proceedings 20030301 |
| Conversion to sirolimus after kidney and liver transplantation: indications and outcomes. | Transplantation proceedings 20030301 |
| Sirolimus in patients after liver transplantation. | Transplantation proceedings 20030301 |
| Successful retransplantation using rapamycin in a patient with previous calcineurin inhibitor-induced posterior leukoencephalopathy syndrome. | Clinical nephrology 20030301 |
| Rituximab in association with rapamycin for post-transplant lymphoproliferative disease treatment. | Transplant international : official journal of the European Society for Organ Transplantation 20030301 |
| Arterial stents as a therapeutic platform. | Surgical neurology 20030301 |
| [Role of Janus kinase/signal transducer and activator of transcription pathway in mediating mRNA expression of high mobility group box1 protein in the liver in septic rats]. | Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue 20030301 |
| A break-even price calculation for the use of sirolimus-eluting stents in angioplasty. | Clinical therapeutics 20030301 |
| Outcomes of African-American kidney-transplant recipients treated with sirolimus, tacrolimus, and corticosteroids. | Transplantation 20030227 |
| Type 1 insulin-like growth factor regulates MT1-MMP synthesis and tumor invasion via PI 3-kinase/Akt signaling. | Oncogene 20030220 |
| Rapamycin induces heme oxygenase-1 in human pulmonary vascular cells: implications in the antiproliferative response to rapamycin. | Circulation 20030218 |
| Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression. | Blood 20030215 |
| [Sirolimus offers advantages for kidney transplant patients]. | Medizinische Klinik (Munich, Germany : 1983) 20030215 |
| Evidence that cyclin D1 mediates both growth and proliferation downstream of TOR in hepatocytes. | The Journal of biological chemistry 20030207 |
| Inhibition of amino acid-mTOR signaling by a leucine derivative induces G1 arrest in Jurkat cells. | Biochemical and biophysical research communications 20030207 |
| Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein. | Oncogene 20030206 |
| In-stent stenosis: pathology and implications for the development of drug eluting stents. | Heart (British Cardiac Society) 20030201 |
| Sirolimus and lymphocele formation after kidney transplantation: an immunosuppressive medication as co-factor for a surgical problem? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030201 |
| Phenytoin decreases the blood concentrations of sirolimus in a liver transplant recipient: a case report. | Therapeutic drug monitoring 20030201 |
| Sirolimus monotherapy in nephrotoxicity due to calcineurin inhibitors in liver transplant recipients. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20030201 |
| Combination of caspofungin with inhibitors of the calcineurin pathway attenuates growth in vitro in Aspergillus species. | The Journal of antimicrobial chemotherapy 20030201 |
| Insulin-like growth factor-I and the cytokines IL-3 and IL-4 promote survival of progenitor myeloid cells by different mechanisms. | Journal of neuroimmunology 20030201 |
| Early experience with sirolimus in lung transplant recipients with chronic allograft rejection. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030201 |
| Interstitial pneumonitis associated with sirolimus: a dilemma for lung transplantation. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030201 |
| [Effects of three different immunosuppressive drugs on SD rat islet cell viability]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20030201 |
| A new era in the treatment of coronary disease? | European heart journal 20030201 |
| Sirolimus antirejection therapy for renal transplantation with cyclosporine-based immunosuppression: case reports. | Transplantation proceedings 20030201 |
| Linear correlation between sirolimus and cyclosporine trough levels in renal transplant patients. | Transplantation proceedings 20030201 |
| Rapamycin induces Smad activity in prostate cancer cell lines. | Urological research 20030201 |
| Sirolimus may promote thrombotic microangiopathy. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030201 |
| Rapamycin as rescue therapy in a patient supported by biventricular assist device to heart transplantation with consecutive ongoing rejection. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20030201 |
| Clinical development of an everolimus pediatric formulation: relative bioavailability, food effect, and steady-state pharmacokinetics. | Journal of clinical pharmacology 20030201 |
| Teaching old drugs new tricks: reincarnating immunosuppressants as antifungal drugs. | Current opinion in investigational drugs (London, England : 2000) 20030201 |
| Rapamycin reduces neointima formation during vascular injury. | VASA. Zeitschrift fur Gefasskrankheiten 20030201 |
| Effect of sirolimus in combination with low-dose cyclosporine and steroids on acute renal allograft rejection. | Journal of the Formosan Medical Association = Taiwan yi zhi 20030201 |
| [Regulatory mechanisms and the influence of immunosuppressive drugs on liver regeneration after partial hepatectomy]. | Polskie Archiwum Medycyny Wewnetrznej 20030201 |
| Two-year angiographic and intravascular ultrasound follow-up after implantation of sirolimus-eluting stents in human coronary arteries. | Circulation 20030128 |
| Drug-eluting stents in vascular intervention. | Lancet (London, England) 20030118 |
| In vivo and in vitro effects of SAR 943, a rapamycin analogue, on airway inflammation and remodeling. | American journal of respiratory and critical care medicine 20030115 |
| Modeling individual variation in biomarker response to combination immunosuppression with stimulated lymphocyte responses-potential clinical implications. | Journal of immunological methods 20030115 |
| Sirolimus-eluting stent for treatment of complex in-stent restenosis: the first clinical experience. | Journal of the American College of Cardiology 20030115 |
| Insulin-like growth factor I-mediated protection from rapamycin-induced apoptosis is independent of Ras-Erk1-Erk2 and phosphatidylinositol 3'-kinase-Akt signaling pathways. | Cancer research 20030115 |
| Combination therapy of mycophenolate mofetil and rapamycin in prevention of chronic renal allograft rejection in the rat. | Transplantation 20030115 |
| Improved freedom from rejection after a loading dose of sirolimus. | Transplantation 20030115 |
| Rapamycin impairs antigen uptake of human dendritic cells. | Transplantation 20030115 |
| Severe acute renal failure after exposure to sirolimus-tacrolimus in two living donor kidney recipients. | Transplantation 20030115 |
| Quantitative analysis of loading and extender acyltransferases of modular polyketide synthases. | Biochemistry 20030114 |
| Sirolimus-eluting stent for the treatment of in-stent restenosis: a quantitative coronary angiography and three-dimensional intravascular ultrasound study. | Circulation 20030107 |
| Rapamycin-induced G1 arrest in cycling B-CLL cells is associated with reduced expression of cyclin D3, cyclin E, cyclin A, and survivin. | Blood 20030101 |
| Modulation of the electrophoretic mobility of the linker for activation of T cells (LAT) by the calcineurin inhibitors CsA and FK506: LAT is a potential substrate for PKC and calcineurin signaling pathways. | Cellular signalling 20030101 |
| Creating polyketide diversity through genetic engineering. | Frontiers in bioscience : a journal and virtual library 20030101 |
| Effects of FK506 on [Ca2+]i differ in mouse and rabbit ventricular myocytes. | The Journal of pharmacology and experimental therapeutics 20030101 |
| Differential regulation of lipogenesis and leptin production by independent signaling pathways and rosiglitazone during human adipocyte differentiation. | Diabetes 20030101 |
| The product of the UTH1 gene, required for Bax-induced cell death in yeast, is involved in the response to rapamycin. | Molecular microbiology 20030101 |
| Drug-eluting stents to prevent reblockage of coronary arteries. | The Journal of cardiovascular nursing 20030101 |
| Tacrolimus and sirolimus decrease oxidative phosphorylation of isolated rat kidney mitochondria. | British journal of pharmacology 20030101 |
| [Opening of ATP-sensitive potassium channel attenuates cardiac remodeling induced by chronic inhibition of nitric oxide synthesis]. | Journal of cardiology 20030101 |
| Metabolic screening of mammalian cell cultures using well-plates. | Biotechnology progress 20030101 |
| Steroid-refractory graft-vs.-host disease: past, present and future. | Pediatric transplantation 20030101 |
| [Edema of the eyelids caused by sirolimus in renal transplant recipients]. | Annales de dermatologie et de venereologie 20030101 |
| Sirolimus eluting stent: a new era in interventional cardiology? | Current pharmaceutical design 20030101 |
| Synergistic effect of vincristine with tacrolimus or sirolimus in prevention of acute heart allograft rejection in the rat. | Microsurgery 20030101 |
| [Epstein Barr viral load monitoring in mononuclear lymphocytes and serum of renal transplant recipients using a quantitative PCR protocol]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20030101 |
| Morphological and biochemical effects of immunosuppressive drugs in a capillary tube assay for endothelial dysfunction. | Clinical transplantation 20030101 |
| A pilot protocol of a calcineurin-inhibitor free regimen for kidney transplant recipients of marginal donor kidneys or with delayed graft function. | Clinical transplantation 20030101 |
| [Therapeutic drug monitoring of mycophenolate mofetil, sirolimus and cyclosporine at C2]. | Annales de biologie clinique 20030101 |
| c-Myc oncoprotein: cell cycle-related events and new therapeutic challenges in cancer and cardiovascular diseases. | Cell cycle (Georgetown, Tex.) 20030101 |
| A bicyclic monoterpene diol and UVB stimulate BRCA1 phosphorylation in human keratinocytes. | Photochemistry and photobiology 20030101 |
| Structures of immunophilins and their ligand complexes. | Current topics in medicinal chemistry 20030101 |
| Rapamycins: mechanism of action and cellular resistance. | Cancer biology & therapy 20030101 |
| Oral rapamycin inhibits growth of atherosclerotic plaque in apoE knock-out mice. | Cardiovascular radiation medicine 20030101 |
| [Drug releasing stents]. | Archivos de cardiologia de Mexico 20030101 |
| Influence of immunosuppressive drugs on dendritic cells. | Transplant immunology 20030101 |
| New regimen for kidney transplants. | FDA consumer 20030101 |
| New drug-device combination helps keep arteries open. | FDA consumer 20030101 |
| The molecular target of rapamycin (mTOR) as a therapeutic target against cancer. | Cancer biology & therapy 20030101 |
| Synergistic effects of RAD and Neoral in inhibition of host-vs.-graft and graft-vs.-host immune responses in rat small-bowel transplantation. | Microsurgery 20030101 |
| Renal transplantation: basic concepts and evolution of therapy. | Journal of clinical apheresis 20030101 |
| [Recent trend in interventional cardiology--drug-containing stents]. | Terapevticheskii arkhiv 20030101 |
| Role of calcineurin in calcium-mediated hypoxic injury to white matter. | The spine journal : official journal of the North American Spine Society 20030101 |
| Cap-dependent translation and control of the cell cycle. | Progress in cell cycle research 20030101 |
| Islet of Langerhans transplantation for the treatment of type 1 diabetes. | Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera 20030101 |
| [Side effects and toxicity of immunosuppressive agents]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20030101 |
| Inflammation and restenosis: implications for therapy. | Annals of medicine 20030101 |
| Insulin-like growth factor binding protein-6 and CCI-779, an ester analogue of rapamycin, additively inhibit rhabdomyosarcoma growth. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030101 |
| The sirolimus-eluting stent: a review of its use in the treatment of coronary artery disease. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101 |
| Intracoronary brachytherapy following drug-eluting stent failure. It's still not time to hang up the spikes! | Cardiovascular radiation medicine 20030101 |
| Kidney and pancreas transplantation at Wake Forest University Baptist Medical Center. | Clinical transplants 20030101 |
| [Rapamycin: from the laboratory to the treatment of patients' arteries]. | Revista espanola de cardiologia 20030101 |
| Localisation and regulation of the eIF4E-binding protein 4E-BP3. | FEBS letters 20021218 |
| Improved renal function in sirolimus-treated renal transplant patients after early cyclosporine elimination. | Transplantation 20021215 |
| Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy. | Cancer research 20021215 |
| Drug eluting coronary stents. | BMJ (Clinical research ed.) 20021207 |
| Effects of immunosuppressants, calcineurin inhibition, and blockade of endoplasmic reticulum calcium channels on free fatty acid efflux from the ischemic/reperfused rat cerebral cortex. | Brain research 20021206 |
| Influence of the new immunosuppressive combinations on arterial hypertension after renal transplantation. | Kidney international. Supplement 20021201 |
| Rapamycin potentiates transforming growth factor beta-induced growth arrest in nontransformed, oncogene-transformed, and human cancer cells. | Molecular and cellular biology 20021201 |
| Clonal anergy is maintained independently of T cell proliferation. | Journal of immunology (Baltimore, Md. : 1950) 20021201 |
| Programmed death-1 targeting can promote allograft survival. | Journal of immunology (Baltimore, Md. : 1950) 20021201 |
| Measurement of whole blood sirolimus by an HPLC assay using solid-phase extraction and UV detection. | Therapeutic drug monitoring 20021201 |
| Inhibition of autophagy in mitotic animal cells. | Traffic (Copenhagen, Denmark) 20021201 |
| Differential Effect of sirolimus vs prednisolone in the treatment of sclerosing encapsulating peritonitis. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20021201 |
| Review of the proliferation inhibitor everolimus. | Expert opinion on investigational drugs 20021201 |
| Histopathological study of intrahepatic islets transplanted in the nonhuman primate model using edmonton protocol immunosuppression. | The Journal of clinical endocrinology and metabolism 20021201 |
| Sirolimus: new preparation. No tangible advance in renal transplantation. | Prescrire international 20021201 |
| Evaluation for synergistic suppression of T cell responses to minor histocompatibility antigens by chloroquine in combination with tacrolimus and a rapamycin derivative, SDZ-RAD. | Bone marrow transplantation 20021201 |
| Sirolimus-eluting coronary stents. | Journal of interventional cardiology 20021201 |
| T-stenting with drug-eluting stents for the treatment of bifurcation in-stent restenosis. | Journal of interventional cardiology 20021201 |
| Studies of cargo delivery to the vacuole mediated by autophagosomes in Saccharomyces cerevisiae. | Developmental cell 20021201 |
| Effect of sirolimus on ischemia/reperfusion injury in transgenic hypertensive rat. | Transplantation proceedings 20021201 |
| Basiliximab-sirolimus-prednisone induction regimen followed by delayed low-dose cyclosporine in renal transplant recipients of living donors. | Transplantation proceedings 20021201 |
| Sirolimus rescue treatment in calcineurin-inhibitor nephrotoxicity after kidney transplantation. | Transplantation proceedings 20021201 |
| Immunosuppression with sirolimus/tacrolimus combination in pancreas transplantation: 1-year results. | Transplantation proceedings 20021201 |
| Interaction of immunosuppressive agents rapamycin and its analogue SDZ-RAD with endothelial P-gp. | Transplantation proceedings 20021201 |
| Regulation of subtelomeric silencing during stress response. | Molecular cell 20021201 |
| Maf1 is an essential mediator of diverse signals that repress RNA polymerase III transcription. | Molecular cell 20021201 |
| New treatment for clogged coronary arteries. | Mayo Clinic health letter (English ed.) 20021201 |
| [To further improve transplantation results]. | Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen 20021201 |
| Fluconazole-sirolimus drug interaction. | Transplantation 20021127 |
| Images in Cardiovascular Medicine. True three-dimensional reconstructed images showing lumen enlargement after sirolimus-eluting stent implantation. | Circulation 20021126 |
| Kidney transplantation with rabbit antithymocyte globulin induction and sirolimus monotherapy. | Lancet (London, England) 20021123 |
| Synthetic lethality: killing cancer with cancer. | Journal of the National Cancer Institute 20021120 |
| Nuclear translocation of insulin receptor substrate-1 by oncogenes and Igf-I. Effect on ribosomal RNA synthesis. | The Journal of biological chemistry 20021115 |
| BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin. | Blood 20021115 |
| Regulation of the cell integrity pathway by rapamycin-sensitive TOR function in budding yeast. | The Journal of biological chemistry 20021108 |
| The immunosuppressant rapamycin, alone or with transforming growth factor-beta, enhances osteoclast differentiation of RAW264.7 monocyte-macrophage cells in the presence of RANK-ligand. | Calcified tissue international 20021101 |
| Different mechanisms are utilized by HIV-1 Nef and staphylococcal enterotoxin A to control and regulate interleukin-10 production. | Immunology letters 20021101 |
| The immunosuppressant rapamycin represses human immunodeficiency virus type 1 replication. | Antimicrobial agents and chemotherapy 20021101 |
| Combined effects of calcineurin inhibitors or sirolimus with anti-CD40L mAb on alloengraftment under nonmyeloablative conditions. | Blood 20021101 |
| Effects of the combination of rapamycin with tacrolimus or cyclosporin on experimental intimal hyperplasia. | The British journal of surgery 20021101 |
| Sirolimus (Rapamune) in renal transplantation. | Current opinion in nephrology and hypertension 20021101 |
| Therapeutic drug monitoring of immunosuppressive drugs in kidney transplantation. | Current opinion in nephrology and hypertension 20021101 |
| Drug-eluting stent: the 'magic bullet' for prevention of restenosis? | Basic research in cardiology 20021101 |
| Fate of side branches after coronary arterial sirolimus-eluting stent implantation. | The American journal of cardiology 20021101 |
| New insights into the interactions between T-cell costimulatory blockade and conventional immunosuppressive drugs. | Annals of surgery 20021101 |
| Ras/Erk signaling is essential for activation of protein synthesis by Gq protein-coupled receptor agonists in adult cardiomyocytes. | Circulation research 20021101 |
| Inhibitors of mTOR reverse doxorubicin resistance conferred by PTEN status in prostate cancer cells. | Cancer research 20021101 |
| Ca(2+)-dependent interaction between FKBP12 and calcineurin regulates activity of the Ca(2+) release channel in skeletal muscle. | Biophysical journal 20021101 |
| Sirolimus and FTY720: new approaches to transplant immunosuppression. | Transplantation proceedings 20021101 |
| Effect of rapamycin and prednisolone in differentiated THP-1 and U937 cells. | Transplantation proceedings 20021101 |
| Pharmacodynamics of sirolimus and cyclosporine combination therapy. | Transplantation proceedings 20021101 |
| Sirolimus attenuates the expression of metalloproteinase-2 and -9 and inhibits intimal hyperplasia following balloon angioplasty. | Transplantation proceedings 20021101 |
| Rituximab and rapamycin for posttransplant lymphoproliferative disease treatment: report of three cases. | Transplantation proceedings 20021101 |
| Flow cytometric detection of intracellular IL-12 release: in vitro effect of widely used immunosuppressants. | International immunopharmacology 20021101 |
| [Treatment of diabetes mellitus in patients after renal transplantation]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20021101 |
| [Effect of immunosuppressive treatment on diurnal profile of blood pressure]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20021101 |
| Systemic drug therapy for restenosis: 'déjà vu all over again'. | Circulation 20021029 |
| Oral everolimus inhibits in-stent neointimal growth. | Circulation 20021029 |
| Kidney transplantation without calcineurin inhibitor drugs: a prospective, randomized trial of sirolimus versus cyclosporine. | Transplantation 20021027 |
| Sirolimus-eluting coronary stents. | The New England journal of medicine 20021017 |
| Activated mammalian target of rapamycin pathway in the pathogenesis of tuberous sclerosis complex renal tumors. | Cancer research 20021015 |
| The group I metabotropic glutamate receptor agonist (S)-3,5-dihydroxyphenylglycine induces a novel form of depotentiation in the CA1 region of the hippocampus. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20021015 |
| Oral efficacy of the new immunomodulator FTY720 in cynomolgus monkey kidney allotransplantation, given alone or in combination with cyclosporine or RAD. | Transplantation 20021015 |
| Multiple signalling pathways mediate insulin-stimulated gene expression in 3T3-L1 adipocytes. | Biochimica et biophysica acta 20021011 |
| Angiographic findings of the multicenter Randomized Study With the Sirolimus-Eluting Bx Velocity Balloon-Expandable Stent (RAVEL): sirolimus-eluting stents inhibit restenosis irrespective of the vessel size. | Circulation 20021008 |
| Phosphorylation-dependent interaction of the asialoglycoprotein receptor with molecular chaperones. | The Journal of biological chemistry 20021004 |
| Identification of TOR signaling complexes: more TORC for the cell growth engine. | Cell 20021004 |
| Proliferation of IL-6-independent multiple myeloma does not require the activity of extracellular signal-regulated kinases (ERK1/2). | Journal of cellular physiology 20021001 |
| Activation of multiple signaling modules is critical in angiotensin IV-induced lung endothelial cell proliferation. | American journal of physiology. Lung cellular and molecular physiology 20021001 |
| The FKBP12-rapamycin-associated protein (FRAP) is a CLIP-170 kinase. | EMBO reports 20021001 |
| Cyclosporin-A differentially affects apoptosis during in vivo rat thymocyte maturation. | Scandinavian journal of immunology 20021001 |
| A novel pathway regulating the mammalian target of rapamycin (mTOR) signaling. | Biochemical pharmacology 20021001 |
| Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate. | The Journal of pharmacology and experimental therapeutics 20021001 |
| Hepatocyte growth factor induced human trophoblast motility involves phosphatidylinositol-3-kinase, mitogen-activated protein kinase, and inducible nitric oxide synthase. | Experimental cell research 20021001 |
| Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during antigen presentation. | Journal of immunology (Baltimore, Md. : 1950) 20021001 |
| Impact of immunosuppressive therapy on recurrence of hepatitis C. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20021001 |
| Sirolimus eluting stent in the treatment of atherosclerosis coronary artery disease. | Minerva cardioangiologica 20021001 |
| Drug-eluting stents. | Minerva cardioangiologica 20021001 |
| Drug-eluting stent: the emerging technique for the prevention of restenosis. | Minerva cardioangiologica 20021001 |
| Drug-eluting stents: clinical experiences and perspectives. | Minerva cardioangiologica 20021001 |
| Drug eluting stents: managing coronary artery stenosis following PTCA. | Issues in emerging health technologies 20021001 |
| Cardiovascular toxicities of immunosuppressive agents. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20021001 |
| Constitutive activation of p70S6k in cancer cells. | Archives of pharmacal research 20021001 |
| Dimerizer-regulated gene expression. | Current opinion in biotechnology 20021001 |
| Calcineurin inhibitors and sirolimus: mechanisms of action and applications in dermatology. | Clinical and experimental dermatology 20021001 |
| Sirolimus-eluting stents: the novel application of basic science to coronary artery disease. | Irish medical journal 20021001 |
| The '0%' restenosis study. | Italian heart journal : official journal of the Italian Federation of Cardiology 20021001 |
| Clinical development of mammalian target of rapamycin inhibitors. | Hematology/oncology clinics of North America 20021001 |
| Incidence, therapy, and consequences of lymphocele after sirolimus-cyclosporine-prednisone immunosuppression in renal transplant recipients. | Transplantation 20020927 |
| Artificial mammalian gene regulation networks-novel approaches for gene therapy and bioengineering. | Journal of biotechnology 20020925 |
| Persistent inhibition of neointimal hyperplasia after sirolimus-eluting stent implantation: long-term (up to 2 years) clinical, angiographic, and intravascular ultrasound follow-up. | Circulation 20020924 |
| Convergence of the target of rapamycin and the Snf1 protein kinase pathways in the regulation of the subcellular localization of Msn2, a transcriptional activator of STRE (Stress Response Element)-regulated genes. | The Journal of biological chemistry 20020920 |
| Sirolimus-eluting stents for the treatment of obstructive superficial femoral artery disease: six-month results. | Circulation 20020917 |
| Sirolimus-induced leukocytoclastic vasculitis. | Transplantation 20020915 |
| American Chemical Society meeting. Chemists search for solutions. | Science (New York, N.Y.) 20020913 |
| TOR deficiency in C. elegans causes developmental arrest and intestinal atrophy by inhibition of mRNA translation. | Current biology : CB 20020903 |
| Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling. | Nature cell biology 20020901 |
| Role of the p70 S6 kinase cascade in neutrophilic differentiation and proliferation of HL-60 cells-a study of transferrin receptor-positive and -negative cells obtained from dimethyl sulfoxide- or retinoic acid-treated HL-60 cells. | Archives of biochemistry and biophysics 20020901 |
| Effect of insulin-like growth factor II on protecting myoblast cells against cisplatin-induced apoptosis through p70 S6 kinase pathway. | Neoplasia (New York, N.Y.) 20020901 |
| Mycophenolic acid inhibits IL-2-dependent T cell proliferation, but not IL-2-dependent survival and sensitization to apoptosis. | Journal of immunology (Baltimore, Md. : 1950) 20020901 |
| Delayed wound healing with sirolimus after liver transplant. | The Annals of pharmacotherapy 20020901 |
| Nelfinavir, a protease inhibitor, increases sirolimus levels in a liver transplantation patient: a case report. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20020901 |
| No delayed restenosis at 18 months after implantation of sirolimus-eluting stent. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020901 |
| Drug-eluting stents for the prevention of restenosis: Standing the test of time. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020901 |
| Enhanced sensitivity of multiple myeloma cells containing PTEN mutations to CCI-779. | Cancer research 20020901 |
| Comparative study of cyclosporine and tacrolimus vs newer immunosuppressants mycophenolate mofetil and rapamycin on coronary endothelial function. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020901 |
| Everolimus (Certican) in combination with neoral in pediatric renal transplant recipients: interim analysis after 3 months. | Transplantation proceedings 20020901 |
| Long-term pharmacokinetics of the metabolites of everolimus and cyclosporine in renal transplant recipients. | Transplantation proceedings 20020901 |
| Sirolimus in late acute OKT3-resistant and/or steroid-resistant rejection after simultaneous pancreas and kidney transplantation. | Transplantation proceedings 20020901 |
| Onset of liver regeneration after subtotal resection is inhibited by the use of new immunosuppressive drugs. | Transplantation proceedings 20020901 |
| Can we prevent in-stent restenosis? | Current opinion in cardiology 20020901 |
| Care of the kidney transplant recipient. Vigilant monitoring creates the best outcome. | Postgraduate medicine 20020901 |
| [Drug-eluding stents: bis repetita?]. | Archives des maladies du coeur et des vaisseaux 20020901 |
| Two TOR complexes, only one of which is rapamycin sensitive, have distinct roles in cell growth control. | Molecular cell 20020901 |
| Goosebumps. | Lancet (London, England) 20020831 |
| Regulation of ribosomal S6 kinase 2 by mammalian target of rapamycin. | The Journal of biological chemistry 20020830 |
| Immunologic mechanisms in tolerance produced in mice with nonradiation-based lymphoablation and donor-specific bone marrow. | Transplantation 20020827 |
| Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM). | The Journal of biological chemistry 20020823 |
| Differential contributions of ERK and PI3-kinase to the regulation of cyclin D1 expression and to the control of the G1/S transition in mouse embryonic stem cells. | Oncogene 20020815 |
| Intravascular ultrasound findings in the multicenter, randomized, double-blind RAVEL (RAndomized study with the sirolimus-eluting VElocity balloon-expandable stent in the treatment of patients with de novo native coronary artery Lesions) trial. | Circulation 20020813 |
| Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway. | The Journal of biological chemistry 20020802 |
| Effect of immunosuppressive agents on glucocorticoid receptor function in A6 cells. | American journal of physiology. Renal physiology 20020801 |
| Rapamycin inhibits macropinocytosis and mannose receptor-mediated endocytosis by bone marrow-derived dendritic cells. | Blood 20020801 |
| Sirolimus-based immunosuppression for transplant-associated thrombotic microangiopathy. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020801 |
| Sirolimus lowers myeloperoxidase and p-ANCA titers in a pediatric patient before kidney transplantation. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20020801 |
| Signalling pathways and combinatory effects of insulin and amino acids in isolated rat hepatocytes. | European journal of biochemistry 20020801 |
| Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes. | European journal of biochemistry 20020801 |
| Transmitting the signal of excess nitrogen in Saccharomyces cerevisiae from the Tor proteins to the GATA factors: connecting the dots. | FEMS microbiology reviews 20020801 |
| Multiple ion isolation applications in FT-ICR MS: exact-mass MSn internal calibration and purification/interrogation of protein-drug complexes. | Analytical chemistry 20020801 |
| Rapamycin blocks the generation of regulatory T cells facilitated by posttransplant infusion of donor T cells through increasing the apoptosis of thymic CD4(+)CD25(+) cells. | Transplantation proceedings 20020801 |
| Sirolimus inhibits growth of human hepatoma cells in contrast to tacrolimus which promotes cell growth. | Transplantation proceedings 20020801 |
| Inhibition of IL-12 signaling Stat4/IFN-gamma pathway by rapamycin is associated with impaired dendritic [correction of dendritc] cell function. | Transplantation proceedings 20020801 |
| Influence of immunosuppressive drugs on intestinal epithelial transport function. | Transplantation proceedings 20020801 |
| Effect of rapamycin in combination with calcineurin inhibitors, FK506 and cyclosporin, following arterial injury. | Transplantation proceedings 20020801 |
| Sirolimus-based immunosuppressive [correction of immunosuppresive] protocol for calcineurin sparing in liver transplantation. | Transplantation proceedings 20020801 |
| Randomized trial of three different immunosuppressive regimens to prevent chronic renal allograft rejection. | Transplantation proceedings 20020801 |
| Early experience using calcineurin-free protocol in recipients of high-risk cadaver renal transplants. | Transplantation proceedings 20020801 |
| Medium-term outcome using sirolimus-tacrolimus combination in adult renal transplant recipients. | Transplantation proceedings 20020801 |
| A pilot trial of tacrolimus, sirolimus, and steroids in renal transplant recipients. | Transplantation proceedings 20020801 |
| A retrospective analysis of a sirolimus/prograf regimen for the prevention of acute rejection in recipients of primary mismatched renal allografts. | Transplantation proceedings 20020801 |
| Sirolimus-based steroid-free maintenance immunosuppression. | Transplantation proceedings 20020801 |
| Increased frequency of lymphoceles under treatment with sirolimus following renal transplantation: a single center experience. | Transplantation proceedings 20020801 |
| Sirolimus and tacrolimus in clinical cardiac transplantation. | Transplantation proceedings 20020801 |
| Can acute rejection be prevented in SPK transplantation? | Transplantation proceedings 20020801 |
| Rejection-free protocol using sirolimus-tacrolimus combination for pediatric renal transplant recipients. | Transplantation proceedings 20020801 |
| Improved lipid profile and blood sugar control in pediatric renal transplant recipients using sirolimus-tacrolimus combination. | Transplantation proceedings 20020801 |
| Pharmacodynamics of sirolimus in transplanted children receiving tacrolimus. | Transplantation proceedings 20020801 |
| Preliminary immunosuppression withdrawal strategies with sirolimus in children with liver transplants. | Transplantation proceedings 20020801 |
| Nutrient-hormone interaction in the ovine liver: methionine supply selectively modulates growth hormone-induced IGF-I gene expression. | The Journal of endocrinology 20020801 |
| Effects of sirolimus on plasma lipids, lipoprotein levels, and fatty acid metabolism in renal transplant patients. | Journal of lipid research 20020801 |
| Loss of ypk1 function causes rapamycin sensitivity, inhibition of translation initiation and synthetic lethality in 14-3-3-deficient yeast. | Genetics 20020801 |
| CCI-779 Wyeth. | Current opinion in investigational drugs (London, England : 2000) 20020801 |
| The neuronal choline transporter CHT1 is regulated by immunosuppressor-sensitive pathways. | Journal of neurochemistry 20020801 |
| Outcomes of African American kidney transplant recipients treated with sirolimus, tacrolimus, and corticosteroids. | Transplantation 20020727 |
| VIIa/tissue factor interaction results in a tissue factor cytoplasmic domain-independent activation of protein synthesis, p70, and p90 S6 kinase phosphorylation. | The Journal of biological chemistry 20020726 |
| mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. | Cell 20020726 |
| Assessment of sirolimus concentrations in whole blood by high-performance liquid chromatography with ultraviolet detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020715 |
| The impact of novel immunosuppressive agents on infections in organ transplant recipients and the interactions of these agents with antimicrobials. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020701 |
| Termination of cardiac Ca(2+) sparks: an investigative mathematical model of calcium-induced calcium release. | Biophysical journal 20020701 |
| Constitutive and regulated expression of processed insulin following in vivo hepatic gene transfer. | Gene therapy 20020701 |
| Regulation of endogenous gene expression with a small-molecule dimerizer. | Nature biotechnology 20020701 |
| Sirolimus steady-state trough concentrations are not affected by bolus methylprednisolone therapy in renal allograft recipients. | British journal of clinical pharmacology 20020701 |
| Effects of sirolimus on lipids in renal allograft recipients: an analysis using the Framingham risk model. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020701 |
| Mechanisms involved in responses to the poroxisome proliferator WY-14,643 on gap junctional intercellular communication in V79 hamster fibroblasts. | Toxicology and applied pharmacology 20020701 |
| Successful treatment of tacrolimus-associated thrombotic microangiopathy with sirolimus conversion and plasma exchange. | Clinical nephrology 20020701 |
| An unexpected inhibitory effect of rapamycin against germination of spores of Bacillus brevis strain Nagano. | The Journal of antibiotics 20020701 |
| What is 'the matter' with restenosis in 2002? | Circulation 20020625 |
| c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells. | The Journal of biological chemistry 20020621 |
| Global and specific translational control by rapamycin in T cells uncovered by microarrays and proteomics. | The Journal of biological chemistry 20020621 |
| Effect of rapamycin on the cyclosporin A-resistant CD28-mediated costimulatory pathway. | Blood 20020615 |
| Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E. | Genes & development 20020615 |
| Mks1p is required for negative regulation of retrograde gene expression in Saccharomyces cerevisiae but does not affect nitrogen catabolite repression-sensitive gene expression. | The Journal of biological chemistry 20020607 |
| Sirolimus-eluting coronary stents. | The New England journal of medicine 20020606 |
| A randomized comparison of a sirolimus-eluting stent with a standard stent for coronary revascularization. | The New England journal of medicine 20020606 |
| Quantification and stability of everolimus (SDZ RAD) in human blood by high-performance liquid chromatography-electrospray tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020605 |
| Insulinlike growth factor-I signaling in multiple myeloma: downstream elements, functional correlates, and pathway cross-talk. | Blood 20020601 |
| A clinical pharmacokinetic study of tacrolimus and sirolimus combination immunosuppression comparing simultaneous to separated administration. | Therapeutic drug monitoring 20020601 |
| Effect of rifampin on apparent clearance of everolimus. | The Annals of pharmacotherapy 20020601 |
| Rapid liquid chromatography-tandem mass spectrometry routine method for simultaneous determination of sirolimus, everolimus, tacrolimus, and cyclosporin A in whole blood. | Clinical chemistry 20020601 |
| In vitro evaluation of motilin agonism by macrolide immunosuppressive drugs. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020601 |
| Sirolimus tolerability in a kidney transplant recipient with acute intermittent porphyria. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20020601 |
| Hypoxia enhances vascular cell proliferation and angiogenesis in vitro via rapamycin (mTOR)-dependent signaling. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020601 |
| The effects of rapamycin in murine peripheral nerve isografts and allografts. | Plastic and reconstructive surgery 20020601 |
| Rapamycin induces binding activity to the terminal oligopyrimidine tract of ribosomal protein mRNA in rats. | Archives of biochemistry and biophysics 20020601 |
| Sirolimus/cyclosporine/tacrolimus interactions on bile flow and biliary excretion of immunosuppressants in a subchronic bile fistula rat model. | British journal of pharmacology 20020601 |
| Implication of alpha4 phosphoprotein and the rapamycin-sensitive mammalian target-of-rapamycin pathway in prolactin receptor signalling. | The Journal of endocrinology 20020601 |
| Combined immunosuppression with cyclosporine, rapamycin, and mycophenolate mofetil controls rejection with minimal nutritional impact in experimental small intestinal transplantation. | Transplantation proceedings 20020601 |
| Influence of a novel rapamycin analogon SDZ RAD on endothelial tissue factor and adhesion molecule expression. | Transplantation proceedings 20020601 |
| Prolongation of fully allogeneic skin graft survival in the rat by combined administration of costimulatory blockade and sirolimus. | Transplantation proceedings 20020601 |
| Role of immunosuppressive drugs in the development of tissue-invasive cytomegalovirus infection in renal transplant recipients. | Transplantation proceedings 20020601 |
| New developments in immunosuppressive therapy in renal transplantation. | Expert opinion on biological therapy 20020601 |
| Rapamycin and T cell costimulatory blockade as post-transplant treatment promote fully MHC-mismatched allogeneic bone marrow engraftment under irradiation-free conditioning therapy. | Bone marrow transplantation 20020601 |
| The rapamycin analogue SDZ RAD attenuates bleomycin-induced pulmonary fibrosis in rats. | The European respiratory journal 20020601 |
| Coated stents: a novel approach to prevent in-stent restenosis. | Italian heart journal : official journal of the Italian Federation of Cardiology 20020601 |
| Modern strategies to prevent coronary restenosis. | Italian heart journal : official journal of the Italian Federation of Cardiology 20020601 |
| Control of proteolysis by norepinephrine and insulin in brown adipocytes: role of ATP, phosphatidylinositol 3-kinase, and p70 S6K. | Canadian journal of physiology and pharmacology 20020601 |
| [Metabolic modifications related to immunosuppressive drugs]. | Revue medicale de Bruxelles 20020601 |
| Regulation of an activated S6 kinase 1 variant reveals a novel mammalian target of rapamycin phosphorylation site. | The Journal of biological chemistry 20020531 |
| Intestinal transplantation before and after the introduction of sirolimus. | Transplantation 20020527 |
| Rapamycin blocks tumor progression: unlinking immunosuppression from antitumor efficacy. | Transplantation 20020527 |
| [Consistent success with coated stents. Coronary arteries stay open longer]. | MMW Fortschritte der Medizin 20020523 |
| Ro 31-6045, the inactive analogue of the protein kinase C inhibitor Ro 31-8220, blocks in vivo activation of p70(s6k)/p85(s6k): implications for the analysis of S6K signalling. | FEBS letters 20020522 |
| Control of Ser2448 phosphorylation in the mammalian target of rapamycin by insulin and skeletal muscle load. | The Journal of biological chemistry 20020517 |
| Myogenic differentiation is dependent on both the kinase function and the N-terminal sequence of mammalian target of rapamycin. | The Journal of biological chemistry 20020510 |
| Rapamycin partially prevents insulin resistance induced by chronic insulin treatment. | Biochemical and biophysical research communications 20020510 |
| Images in cardiovascular medicine. Left main rapamycin-coated stent: invasive versus noninvasive angiographic follow-up. | Circulation 20020507 |
| Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6. | The Journal of biological chemistry 20020503 |
| Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy. | Human molecular genetics 20020501 |
| Two novel phosphorylation sites on FKHR that are critical for its nuclear exclusion. | The EMBO journal 20020501 |
| Role of apoptosis in the pathogenesis of acute renal failure. | Current opinion in nephrology and hypertension 20020501 |
| How should the immunosuppressive regimen be managed in patients with established chronic allograft failure? | Kidney international. Supplement 20020501 |
| Sirolimus allows renal recovery in lung and heart transplant recipients with chronic renal impairment. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20020501 |
| Induction of apoptosis and modulation of activation and effector function in T cells by immunosuppressive drugs. | Clinical and experimental immunology 20020501 |
| ARTS I -- the rapamycin eluting stent; ARTS II -- the rosy prophecy. | European heart journal 20020501 |
| Muscarinic acetylcholine receptor activation induces Ca2+ mobilization and Na+/K+-ATPase activity inhibition in eel enterocytes. | The Journal of endocrinology 20020501 |
| Hemolytic uremic syndrome after renal transplantation: immunosuppressive therapy with rapamycin. | Nephron 20020501 |
| Protein modulators made to order. | Chemistry & biology 20020501 |
| Transcriptional response pathways in a yeast strain sensitive to saframycin a and a more potent analog: evidence for a common basis of activity. | Chemistry & biology 20020501 |
| Initial experience using rapamycin immunosuppression in pediatric intestinal transplant recipients. | Transplantation proceedings 20020501 |
| Improved results in small bowel transplantation using sirolimus. | Transplantation proceedings 20020501 |
| Tacrolimus, daclizumab, sirolimus, and budesonide after small bowel transplantation in order to reduce nephrotoxicity. | Transplantation proceedings 20020501 |
| Washing out of lipophilic compounds induces a transient increase in the passive Ca(2+) leak in permeabilized A7r5 cells. | Cell calcium 20020501 |
| Sirolimus does not exhibit nephrotoxicity compared to cyclosporine in renal transplant recipients. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020501 |
| Twenty-eight-day efficacy and phamacokinetics of the sirolimus-eluting stent. | Coronary artery disease 20020501 |
| Drug coating improves stent performance. | Health news (Waltham, Mass.) 20020501 |
| Delayed low-level calcineurin inhibition promotes allospecific tolerance induction by posttransplantation donor leukocyte infusion. | Transplantation 20020427 |
| 4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin. | The Journal of biological chemistry 20020419 |
| Quick guide: target of rapamycin. | Current biology : CB 20020416 |
| Msn2p/Msn4p act as a key transcriptional activator of yeast cytoplasmic thiol peroxidase II. | The Journal of biological chemistry 20020405 |
| Rapamycin eluting stent: the onset of a new era in interventional cardiology. | Heart (British Cardiac Society) 20020401 |
| Identification of a novel route of extraction of sirolimus in human small intestine: roles of metabolism and secretion. | The Journal of pharmacology and experimental therapeutics 20020401 |
| Translational control of cell fate: availability of phosphorylation sites on translational repressor 4E-BP1 governs its proapoptotic potency. | Molecular and cellular biology 20020401 |
| Fighting restenosis from the inside out. | Harvard heart letter : from Harvard Medical School 20020401 |
| Rapamune. New tablet combats kidney rejection. | Nursing 20020401 |
| Long-term care of pediatric renal transplant patients: from bench to bedside. | Current opinion in pediatrics 20020401 |
| Single-dose pharmacokinetics and tolerability of everolimus in stable pediatric renal transplant patients. | Pediatric transplantation 20020401 |
| Efficacy and toxicity of a protocol using sirolimus, tacrolimus and daclizumab in a nonhuman primate renal allotransplant model. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20020401 |
| The role of phosphatidylinositol 3-kinase, rho family GTPases, and STAT3 in Ros-induced cell transformation. | The Journal of biological chemistry 20020329 |
| Long-term kidney graft survival by delayed T cell ablative treatment in rhesus monkeys. | Transplantation 20020327 |
| Compared to mycophenolate mofetil, rapamycin induces significant changes on growth factors and growth factor receptors in the early days post-kidney transplantation. | Transplantation 20020327 |
| Exposure-response relationships for everolimus in de novo kidney transplantation: defining a therapeutic range. | Transplantation 20020327 |
| Insulin regulation of insulin-like growth factor-binding protein-1 gene expression is dependent on the mammalian target of rapamycin, but independent of ribosomal S6 kinase activity. | The Journal of biological chemistry 20020322 |
| Intracellular sensing of amino acids in Xenopus laevis oocytes stimulates p70 S6 kinase in a target of rapamycin-dependent manner. | The Journal of biological chemistry 20020322 |
| Phosphorylation of 4E-BP1 is mediated by the p38/MSK1 pathway in response to UVB irradiation. | The Journal of biological chemistry 20020315 |
| De novo hemolytic uremic syndrome after kidney transplantation in patients treated with cyclosporine-sirolimus combination. | Transplantation 20020315 |
| Regulation of cap-dependent translation by insulin-like growth factor-1 in neuronal cells. | Biochemical and biophysical research communications 20020301 |
| The future role of target of rapamycin inhibitors in renal transplantation. | Current opinion in urology 20020301 |
| Stent-based antirestenotic coatings (sirolimus/paclitaxel). | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020301 |
| Drug-eluting stents for the prevention of restenosis: in quest for the Holy Grail. | Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions 20020301 |
| Combination therapy with sirolimus and interleukin-2 prevents spontaneous and recurrent autoimmune diabetes in NOD mice. | Diabetes 20020301 |
| Strategies to reduce toxicities and improve outcomes in renal transplant recipients. | Pharmacotherapy 20020301 |
| Long-term viability of articular cartilage after microsurgical whole-joint transplantation and immunosuppression with rapamycin, mycophenolate mofetil, and tacrolimus. | The Journal of hand surgery 20020301 |
| The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress. | Molecular cell 20020301 |
| Simultaneous quantification of sirolimus, everolimus, tacrolimus and cyclosporine by liquid chromatography-mass spectrometry (LC-MS). | Clinical chemistry and laboratory medicine 20020301 |
| Mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitors restore anoikis sensitivity in human breast cancer cell lines with a constitutively activated extracellular-regulated kinase (ERK) pathway. | Molecular cancer therapeutics 20020301 |
| Bibliography. Current world literature. Renal medicine and renal transplantation. | Current opinion in urology 20020301 |
| FK506 induces chondrogenic differentiation of clonal mouse embryonic carcinoma cells, ATDC5. | European journal of pharmacology 20020222 |
| Effect of topical immunomodulators on acute allergic inflammation and bronchial hyperresponsiveness in sensitised rats. | European journal of pharmacology 20020222 |
| Overcoming restenosis with sirolimus: from alphabet soup to clinical reality. | Lancet (London, England) 20020216 |
| Cyclosporin A, FK506 and rapamycin produce multiple, temporally distinct, effects on memory following single-trial, passive avoidance training in the chick. | Brain research 20020215 |
| Early expression of myocardial HIF-1alpha in response to mechanical stresses: regulation by stretch-activated channels and the phosphatidylinositol 3-kinase signaling pathway. | Circulation research 20020208 |
| Identification of genes coding enzymes for ascomycin tetra-hydropyranose ring formation. | International journal of molecular medicine 20020201 |
| Update on pharmacokinetic/pharmacodynamic studies with FTY720 and sirolimus. | Therapeutic drug monitoring 20020201 |
| Early clinical experience with a novel rapamycin derivative. | Therapeutic drug monitoring 20020201 |
| International Federation of Clinical Chemistry/International Association of Therapeutic Drug Monitoring and Clinical Toxicology working group on immunosuppressive drug monitoring. | Therapeutic drug monitoring 20020201 |
| BCR signal through alpha 4 is involved in S6 kinase activation and required for B cell maturation including isotype switching and V region somatic hypermutation. | International immunology 20020201 |
| Calcineurin inhibitor-free CD28 blockade-based protocol protects allogeneic islets in nonhuman primates. | Diabetes 20020201 |
| Rapamycin inhibits primary and metastatic tumor growth by antiangiogenesis: involvement of vascular endothelial growth factor. | Nature medicine 20020201 |
| New tools for prevention of restenosis could decrease the 'oculo-stento' reflex. | Cardiovascular research 20020201 |
| Pharmacokinetic and pharmacodynamic assessments of HMG-CoA reductase inhibitors when coadministered with everolimus. | Journal of clinical pharmacology 20020201 |
| Effect of food on everolimus absorption: quantification in healthy subjects and a confirmatory screening in patients with renal transplants. | Pharmacotherapy 20020201 |
| Mammalian target of rapamycin (mTOR): pro- and anti-apoptotic. | Cell death and differentiation 20020201 |
| A novel conditional Akt 'survival switch' reversibly protects cells from apoptosis. | Gene therapy 20020201 |
| Protein phosphatase 2A on track for nutrient-induced signalling in yeast. | Molecular microbiology 20020201 |
| Combination therapy with low dose sirolimus and tacrolimus is synergistic in preventing spontaneous and recurrent autoimmune diabetes in non-obese diabetic mice. | Diabetologia 20020201 |
| [Radioactive stents: problems and potential solutions]. | Herz 20020201 |
| Early cyclosporine a withdrawal in kidney transplant recipients under a sirolimus-based immunosuppressive regimen: pathological study of graft biopsies at 1-year posttransplant. | Transplantation proceedings 20020201 |
| Immunosuppression with sirolimus, cyclosporyne, and prednisone in renal transplantation. | Transplantation proceedings 20020201 |
| The limitations of calcineurin and mTOR inhibitors: new directions for immunosuppressive strategies. | Transplantation proceedings 20020201 |
| Inhibitors of mammalian target of rapamycin as novel antitumor agents: from bench to clinic. | Current opinion in investigational drugs (London, England : 2000) 20020201 |
| Swinging the vote for rapamycin. | Nature reviews. Cancer 20020201 |
| Coating stents with antirestenotic drugs: the blunderbuss or the magic bullet? | Circulation 20020129 |
| Rapamycin increases transforming growth factor-beta mRNA expression in immortalized rat proximal renal tubular cells. | Transplantation 20020127 |
| Increased activity of c-Src and Csk in fibroblasts transformed by v-src oncogene. | Biochemical and biophysical research communications 20020118 |
| Igs from patients with Graves' disease induce the expression of T cell chemoattractants in their fibroblasts. | Journal of immunology (Baltimore, Md. : 1950) 20020115 |
| Selective inhibitor of Janus tyrosine kinase 3, PNU156804, prolongs allograft survival and acts synergistically with cyclosporine but additively with rapamycin. | Blood 20020115 |
| Cell cycle kinesis in lymphocytes in the diagnosis of Alzheimer's disease. | Neuroscience letters 20020111 |
| Autocrine heregulin generates growth factor independence and blocks apoptosis in colon cancer cells. | Oncogene 20020103 |
| Inhibition of PI3K/p70 S6K and p38 MAPK cascades increases osteoblastic differentiation induced by BMP-2. | FEBS letters 20020102 |
| FK506 enhanced osteoblastic differentiation in mesenchymal cells. | Cell biology international 20020101 |
| Synergism of RAD and cyclosporin A in prevention of acute rat corneal allograft rejection. | Cornea 20020101 |
| MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders. | BMC cell biology 20020101 |
| Differential influence of two cyclosporine formulations on everolimus pharmacokinetics: a clinically relevant pharmacokinetic interaction. | Journal of clinical pharmacology 20020101 |
| Post-liver transplantation immunosuppression: the song does not remain the same. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20020101 |
| Preparing for the introduction of new technologies: who is going to pay for them? | The Journal of cardiovascular management : the official journal of the American College of Cardiovascular Administrators 20020101 |
| Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis. | Arthritis research 20020101 |
| Vector algebra in the analysis of genome-wide expression data. | Genome biology 20020101 |
| Current immunosuppression in liver transplantation. | American journal of therapeutics 20020101 |
| Quantification of sirolimus by liquid chromatography-tandem mass spectrometry using on-line solid-phase extraction. | Clinical chemistry and laboratory medicine 20020101 |
| Novel pharmacotherapeutic approaches to prevention and treatment of GVHD. | Drugs 20020101 |
| Newer immunosuppressive drugs: their potential role in rheumatoid arthritis therapy. | Drugs 20020101 |
| Role of mTOR in the degradation of IRS-1: regulation of PP2A activity. | Journal of cellular biochemistry 20020101 |
| Drug-eluting stents in the treatment of atherosclerotic coronary heart disease. | Indian heart journal 20020101 |
| [The novel immunodepressant rapamune]. | Eksperimental'naia i klinicheskaia farmakologiia 20020101 |
| Single-agent immunosuppression after liver transplantation: what is possible? | Drugs 20020101 |
| Optimization and direct comparison of the dimerizer and reverse tet transcriptional control systems. | The journal of gene medicine 20020101 |
| Sirolimus: has it gained from experience with older drugs? | Therapie 20020101 |
| Sirolimus-eluting stents: the novel application of basic science to coronary artery disease. | Irish medical journal 20020101 |
| [Problem with restenosis in connection to balloon angioplasty near to be solved]. | Duodecim; laaketieteellinen aikakauskirja 20020101 |
| Side-chain modified vitamin D analogs require activation of both PI 3-K and erk1,2 signal transduction pathways to induce differentiation of human promyelocytic leukemia cells. | Acta biochimica Polonica 20020101 |
| Calcineurin inhibitor-induced chronic nephrotoxicity in liver transplant patients is reversible using rapamycin as the primary immunosuppressive agent. | Clinical transplantation 20020101 |
| Four birds with one stone: RAPA as potential anticancer therapy. | Cancer biology & therapy 20020101 |
| The macrolide immunosuppressants in dermatology: mechanisms of action. | European journal of dermatology : EJD 20020101 |
| Rapamycin insensitivity in Schistosoma mansoni is not due to FKBP12 functionality. | Molecular and biochemical parasitology 20020101 |
| Clinical experience with drug-eluting stents. | Reviews in cardiovascular medicine 20020101 |
| What will be the impact of drug-eluting stents on hybrid coronary revascularization? | The heart surgery forum 20020101 |
| Drug eluting stents: initial experiences. | Zeitschrift fur Kardiologie 20020101 |
| Sirolimus-eluting stents: a review of experimental and clinical findings. | Zeitschrift fur Kardiologie 20020101 |
| Perspectives of drug-eluting stents: the next revolution. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20020101 |
| Super stents keep the blood flowing. New technology leaves damaged arteries wide open and unclogged. | Heart advisor 20020101 |
| Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease. | Transplantation 20011227 |
| Improving tolerability of immunosuppressive regimens. | Transplantation 20011227 |
| Prospective monitoring of BK virus load after discontinuing sirolimus treatment in a renal transplant patient with BK virus nephropathy. | The Journal of infectious diseases 20011201 |
| Regulation of Id2 gene expression by the type 1 IGF receptor and the insulin receptor substrate-1. | Endocrinology 20011201 |
| Tailoring immunosuppressive therapy for renal transplant recipients. | Pediatric transplantation 20011201 |
| The immunomodulatory drugs cyclosporin A, mycophenolate mofetil, and sirolimus (rapamycin) inhibit allergen-induced proliferation and IL-5 production by PBMCs from atopic asthmatic patients. | The Journal of allergy and clinical immunology 20011201 |
| 14-3-3 Proteins are essential for regulation of RTG3-dependent transcription in Saccharomyces cerevisiae. | Yeast (Chichester, England) 20011201 |
| Cyclic stretch enhances the expression and activity of coronary endothelium-derived hyperpolarizing factor synthase. | Hypertension (Dallas, Tex. : 1979) 20011201 |
| Single-point calibration for sirolimus quantification. | Therapeutic drug monitoring 20011201 |
| Nephrotoxicity of immunosuppressive drugs: new insight and preventive strategies. | Current opinion in critical care 20011201 |
| Insulin release and suppression by tacrolimus, rapamycin and cyclosporin A are through regulation of the ATP-sensitive potassium channel. | Diabetes, obesity & metabolism 20011201 |
| Mechanisms of resistance to rapamycins. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20011201 |
| [Mechanism in the cytoplasm accumulation of TOP binding factor]. | The Japanese journal of antibiotics 20011201 |
| Nerve growth factor uses Ras/ERK and phosphatidylinositol 3-kinase cascades to up-regulate the N-methyl-D-aspartate receptor 1 promoter. | The Journal of biological chemistry 20011130 |
| Ribosomal protein S6 phosphorylation and function during late gestation liver development in the rat. | The Journal of biological chemistry 20011130 |
| Phosphatidic acid-mediated mitogenic activation of mTOR signaling. | Science (New York, N.Y.) 20011130 |
| American Heart Association 2001 scientific sessions: late-breaking science-drug-eluting stents. | Circulation 20011120 |
| Brain-derived neurotrophic factor enhances neuronal translation by activating multiple initiation processes: comparison with the effects of insulin. | The Journal of biological chemistry 20011116 |
| Antagonistic roles for CTLA-4 and the mammalian target of rapamycin in the regulation of clonal anergy: enhanced cell cycle progression promotes recall antigen responsiveness. | Journal of immunology (Baltimore, Md. : 1950) 20011115 |
| Activation of Cdh1-dependent APC is required for G1 cell cycle arrest and DNA damage-induced G2 checkpoint in vertebrate cells. | The EMBO journal 20011115 |
| Phosphorylation and local presynaptic protein synthesis in calcium- and calcineurin-dependent induction of crayfish long-term facilitation. | Neuron 20011108 |
| ErbB2-overexpressing human mammary carcinoma cells display an increased requirement for the phosphatidylinositol 3-kinase signaling pathway in anchorage-independent growth. | Oncogene 20011108 |
| Mammalian TOR: a homeostatic ATP sensor. | Science (New York, N.Y.) 20011102 |
| Rapamycin increases the cellular concentration of the BCL-2 protein and exerts an anti-apoptotic effect. | European journal of cancer (Oxford, England : 1990) 20011101 |
| Rapamycin and less immunosuppressive analogs are toxic to Candida albicans and Cryptococcus neoformans via FKBP12-dependent inhibition of TOR. | Antimicrobial agents and chemotherapy 20011101 |
| Macrolactam immunomodulators for topical treatment of inflammatory skin diseases. | Journal of the American Academy of Dermatology 20011101 |
| The sirolimus coated stent: will the Achilles heel of interventional cardiology finally be cured? | European heart journal 20011101 |
| Coronary restenosis elimination with a sirolimus eluting stent: first European human experience with 6-month angiographic and intravascular ultrasonic follow-up. | European heart journal 20011101 |
| Hierarchical phosphorylation of the translation inhibitor 4E-BP1. | Genes & development 20011101 |
| Targeting keratinocyte apoptosis in the treatment of atopic dermatitis and allergic contact dermatitis. | The Journal of allergy and clinical immunology 20011101 |
| Noradrenaline-induced increase in protein synthesis in adult rat cardiomyocytes: involvement of only alpha1A-adrenoceptors. | Naunyn-Schmiedeberg's archives of pharmacology 20011101 |
| Influence of hepatic impairment on everolimus pharmacokinetics: implications for dose adjustment. | Clinical pharmacology and therapeutics 20011101 |
| Distinct regulatory mechanism for p70 S6 kinase beta from that for p70 S6 kinase alpha. | Genes to cells : devoted to molecular & cellular mechanisms 20011101 |
| TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway. | Molecular cell 20011101 |
| Estrogen and rapamycin effects on cell cycle progression in T47D breast cancer cells. | Breast cancer research and treatment 20011101 |
| Sirolimus: a comprehensive review. | Expert opinion on pharmacotherapy 20011101 |
| Mutagenesis of the rapamycin producer Streptomyces hygroscopicus FC904. | The Journal of antibiotics 20011101 |
| Binding of the La autoantigen to the 5' untranslated region of a chimeric human translation elongation factor 1A reporter mRNA inhibits translation in vitro. | Biochimica et biophysica acta 20011031 |
| Provocative effects of the immunosuppressants rapamycin, tacrolimus, and dexamethasone on pneumonitis in contrast to the anti- pneumonitis effects of mycophenolate mofetil. | Transplantation 20011027 |
| Living the dream of no restenosis. | Circulation 20011023 |
| Sustained suppression of neointimal proliferation by sirolimus-eluting stents: one-year angiographic and intravascular ultrasound follow-up. | Circulation 20011023 |
| Rapamycin's resurrection: a new way to target the cancer cell cycle. | Journal of the National Cancer Institute 20011017 |
| Rapamycin may prevent post-transplant lymphoma. | Journal of the National Cancer Institute 20011017 |
| Pharmacological characterization of the putative cADP-ribose receptor. | The Biochemical journal 20011015 |
| A WASp-VASP complex regulates actin polymerization at the plasma membrane. | The EMBO journal 20011015 |
| Rapamycin: clinical results and future opportunities. | Transplantation 20011015 |
| Effect of sirolimus on the metabolism of apoB100- containing lipoproteins in renal transplant patients. | Transplantation 20011015 |
| Failure of hormone therapy in prostate cancer involves systematic restoration of androgen responsive genes and activation of rapamycin sensitive signaling. | Oncogene 20011011 |
| Rapamycin impairs recovery from acute renal failure: role of cell-cycle arrest and apoptosis of tubular cells. | American journal of physiology. Renal physiology 20011001 |
| Internal ribosome entry segment-mediated initiation of c-Myc protein synthesis following genotoxic stress. | The Biochemical journal 20011001 |
| Rapamycin-sensitive phase of 3T3-L1 preadipocyte differentiation after clonal expansion. | Journal of cellular physiology 20011001 |
| Target of rapamycin (TOR) inhibition in renal transplantation: Clinical uses in various populations. Introduction. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001 |
| Cyclosporine elimination in the presence of TOR inhibitors: effects on renal function, acute rejection, and safety. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001 |
| Safety and efficacy of TOR inhibitors and other immunosuppressive regimens in African-American renal transplant recipients. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001 |
| Sirolimus and mycophenolate mofetil for calcineurin-free immunosuppression in renal transplant recipients. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001 |
| Safety and efficacy of TOR inhibitors in pediatric renal transplant recipients. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20011001 |
| From beach to bedside: history of the development of sirolimus. | Therapeutic drug monitoring 20011001 |
| Use of rapamycin in a transplant patient who developed cyclosporin neurotoxicity. | Pediatric nephrology (Berlin, Germany) 20011001 |
| Efficacy of SDZ RAD compared with CsA monotherapyand combined Rad/FTY720 treatment in a murine cardiac allotransplantation model. | Transplant immunology 20011001 |
| Comparative study analyzing effects of sirolimus-cyclosporin and sirolimus-tacrolimus combinations on bile flow in the rat. | Digestive diseases and sciences 20011001 |
| The mammalian target of rapamycin regulates C2C12 myogenesis via a kinase-independent mechanism. | The Journal of biological chemistry 20010928 |
| Lysophosphatidic acid activates the 70-kDa S6 kinase via the lipoxygenase pathway. | Biochemical and biophysical research communications 20010928 |
| Fluvastatin in combination with rad significantly reduces graft vascular disease in rat cardiac allografts. | Transplantation 20010927 |
| Immune cells and immunosuppression in a porcine bronchial model of obliterative bronchiolitis. | Transplantation 20010927 |
| Interstitial pneumonitis associated with sirolimus (rapamycin) therapy after liver transplantation. | Transplantation 20010927 |
| Damaged microtubules can inactivate BCL-2 by means of the mTOR kinase. | Oncogene 20010927 |
| Drug points: Premature osteonecrosis and sirolimus treatment in renal transplantation. | BMJ (Clinical research ed.) 20010922 |
| Immunosuppressant rapamycin inhibits protein kinase C alpha and p38 mitogen-activated protein kinase leading to the inhibition of chondrogenesis. | European journal of pharmacology 20010921 |
| An important role of CDK inhibitor p18(INK4c) in modulating antigen receptor-mediated T cell proliferation. | Journal of immunology (Baltimore, Md. : 1950) 20010915 |
| Sirolimus: another cause of drug-induced interstitial pneumonitis. | Transplantation 20010915 |
| Sirolimus: searching for its niche or a therapy that has come of age? | Transplantation 20010915 |
| Sirolimus allows early cyclosporine withdrawal in renal transplantation resulting in improved renal function and lower blood pressure. | Transplantation 20010915 |
| Characteristics of sirolimus-associated interstitial pneumonitis in renal transplant patients. | Transplantation 20010915 |
| Sirolimus for rescue and primary immunosuppression in transplanted children receiving tacrolimus. | Transplantation 20010915 |
| Interleukin-15 is the main mediator of lymphocyte proliferation in cultures mixed with human kidney tubular epithelial cells. | Transplantation 20010915 |
| Selective inhibition of IL-2 gene expression by IL-2 antisense oligonucleotides blocks heart allograft rejection. | Transplantation 20010915 |
| Role of the sphingosine 1-phosphate receptor EDG-1 in vascular smooth muscle cell proliferation and migration. | Circulation research 20010914 |
| Stent-based delivery of sirolimus reduces neointimal formation in a porcine coronary model. | Circulation 20010904 |
| Bystander activation involving T lymphocytes in herpetic stromal keratitis. | Journal of immunology (Baltimore, Md. : 1950) 20010901 |
| Interleukin-7 promotes survival and cell cycle progression of T-cell acute lymphoblastic leukemia cells by down-regulating the cyclin-dependent kinase inhibitor p27(kip1). | Blood 20010901 |
| Efficacy of sirolimus (rapamycin) administered concomitantly with a subtherapeutic dose of cyclosporin in the treatment of severe psoriasis: a randomized controlled trial. | The British journal of dermatology 20010901 |
| Sirolimus inhibition of lymphocyte proliferation is not antagonized by ciprofloxacin and other quinolone antibiotics. | Transplantation proceedings 20010901 |
| Population pharmacokinetics of everolimus in de novo renal transplant patients: impact of ethnicity and comedications. | Clinical pharmacology and therapeutics 20010901 |
| mTOR, a novel target in breast cancer: the effect of CCI-779, an mTOR inhibitor, in preclinical models of breast cancer. | Endocrine-related cancer 20010901 |
| Regeneration in avian hair cell epithelia: identification of intracellular signals required for S-phase entry. | The European journal of neuroscience 20010901 |
| [Complications in kidney transplantation]. | Presse medicale (Paris, France : 1983) 20010901 |
| [Focus on Islets of Langerhans transplantation]. | Presse medicale (Paris, France : 1983) 20010901 |
| [mTOR and FTY 720 inhibitors]. | Presse medicale (Paris, France : 1983) 20010901 |
| [Immunosuppression, ongoing clinical trials]. | Presse medicale (Paris, France : 1983) 20010901 |
| Cholestasis and regulation of genes related to drug metabolism and biliary transport in rat liver following treatment with cyclosporine A and sirolimus (Rapamycin). | Pharmacology & toxicology 20010901 |
| Everolimus. Novartis. | Current opinion in investigational drugs (London, England : 2000) 20010901 |
| Cross-talk between the ERK and p70 S6 kinase (S6K) signaling pathways. MEK-dependent activation of S6K2 in cardiomyocytes. | The Journal of biological chemistry 20010831 |
| Bench to bedside: the development of rapamycin and its application to stent restenosis. | Circulation 20010821 |
| A maize insulin-like growth factor signals to a transduction pathway that regulates protein synthesis in maize. | The Biochemical journal 20010815 |
| FK506 promotes adenosine release from endothelial cells via inhibition of adenosine kinase. | European journal of pharmacology 20010810 |
| Ammonia regulates VID30 expression and Vid30p function shifts nitrogen metabolism toward glutamate formation especially when Saccharomyces cerevisiae is grown in low concentrations of ammonia. | The Journal of biological chemistry 20010803 |
| Coexpression of CD4 and CD8alpha on rat T-cells in whole blood: a sensitive marker for monitoring T-cell immunosuppressive drugs. | Journal of immunological methods 20010801 |
| HGF- and KGF-induced activation of PI-3K/p70 s6 kinase pathway in corneal epithelial cells: its relevance in wound healing. | Experimental eye research 20010801 |
| Regulation of glycogen synthesis in human muscle cells. | Biochemical Society transactions 20010801 |
| Orthotopic liver transplantation using low-dose tacrolimus and sirolimus. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010801 |
| In vitro immunosuppressive activity of tacrolimus dihydrodiol precursors obtained by chemical oxidation and identification of a new metabolite of SDZ-RAD by electrospray and electrospray-linked scan mass spectrometry. | Journal of mass spectrometry : JMS 20010801 |
| Staurosporine inhibits phosphorylation of translational regulators linked to mTOR. | Cell death and differentiation 20010801 |
| Natural products as immunosuppressive agents. | Natural product reports 20010801 |
| Advances in systemic therapy of small cell cancer of the lung. | Expert review of anticancer therapy 20010801 |
| Cdc25A phosphatase suppresses apoptosis induced by serum deprivation. | Oncogene 20010727 |
| Sirolimus-associated eyelid edema in kidney transplant recipients. | Transplantation 20010715 |
| Phosphorylation regulates the interaction between Gln3p and the nuclear import factor Srp1p. | The Journal of biological chemistry 20010706 |
| Rapamycin blocks sexual development in fission yeast through inhibition of the cellular function of an FKBP12 homolog. | The Journal of biological chemistry 20010706 |
| Flow cytometric quantitation of calcium-dependent and -independent mitogen-stimulation of T cell functions in whole blood: inhibition by immunosuppressive drugs in vitro. | Journal of immunological methods 20010701 |
| Angiotensin II regulates phosphorylation of translation elongation factor-2 in cardiac myocytes. | American journal of physiology. Heart and circulatory physiology 20010701 |
| Rapamycin induces apoptosis in monocyte- and CD34-derived dendritic cells but not in monocytes and macrophages. | Blood 20010701 |
| Combined effect of cyclosporine and sirolimus on improving the longevity of recombinant adenovirus-mediated transgene expression in the retina. | Archives of ophthalmology (Chicago, Ill. : 1960) 20010701 |
| Cell cycle protein expression in vascular smooth muscle cells in vitro and in vivo is regulated through phosphatidylinositol 3-kinase and mammalian target of rapamycin. | Arteriosclerosis, thrombosis, and vascular biology 20010701 |
| Median effect analysis of efficacy versus adverse effects of immunosuppressants. | Clinical pharmacology and therapeutics 20010701 |
| Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain. | British journal of pharmacology 20010701 |
| The effect of different immunosuppressants on alloantigen dependent and independent factors involved in the development of chronic rejection in an animal model. | Annals of the Royal College of Surgeons of England 20010701 |
| New developments in the prophylaxis and treatment of graft versus host disease. | Expert opinion on pharmacotherapy 20010701 |
| Cell cycle and cell migration: new pieces to the puzzle. | Circulation 20010619 |
| Role for p27(Kip1) in Vascular Smooth Muscle Cell Migration. | Circulation 20010619 |
| Activation loop sequences confer substrate specificity to phosphoinositide 3-kinase alpha (PI3Kalpha ). Functions of lipid kinase-deficient PI3Kalpha in signaling. | The Journal of biological chemistry 20010615 |
| Signal transduction pathways involved in phosphorylation and activation of p70S6K following exposure to UVA irradiation. | The Journal of biological chemistry 20010615 |
| Sirolimus rescue therapy for refractory rejection in renal transplantation. | Transplantation 20010615 |
| Effect of low dose cyclosporine and sirolimus on hepatic drug metabolism in the rat1. | Transplantation 20010615 |
| Vascular and cellular mechanisms of chronic renal allograft dysfunction. | Transplantation 20010615 |
| Exploring treatment options in renal transplantation: the problems of chronic allograft dysfunction and drug-related nephrotoxicity. | Transplantation 20010615 |
| Potential therapeutic interventions to avoid or treat chronic allograft dysfunction. | Transplantation 20010615 |
| Regulation of the levels of small heat-shock proteins during differentiation of C2C12 cells. | Experimental cell research 20010610 |
| Coupled gating between cardiac calcium release channels (ryanodine receptors). | Circulation research 20010608 |
| Metabolism of sirolimus and its derivative everolimus by cytochrome P450 3A4: insights from docking, molecular dynamics, and quantum chemical calculations. | Journal of medicinal chemistry 20010607 |
| A high-capacity quantitative mouse model of drug-mediated immunosuppression based on rejection of an allogeneic subcutaneous tumor. | The Journal of pharmacology and experimental therapeutics 20010601 |
| Cell proliferation through forced engagement of c-Kit and Flt-3. | Blood 20010601 |
| Insulin-like growth factor-I augments prolactin and inhibits growth hormone release through distinct as well as overlapping cellular signaling pathways. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20010601 |
| Effect of p27 deficiency and rapamycin on intimal hyperplasia: in vivo and in vitro studies using a p27 knockout mouse model. | Laboratory investigation; a journal of technical methods and pathology 20010601 |
| Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010601 |
| Simultaneous simple and fast quantification of three major immunosuppressants by liquid chromatography--tandem mass-spectrometry. | Clinical biochemistry 20010601 |
| mTOR inhibitors: an overview. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010601 |
| Sirolimus improves the two-year outcome of renal allografts in African-American patients. | Transplant international : official journal of the European Society for Organ Transplantation 20010601 |
| RAD in de novo renal transplantation: comparison of three doses on the incidence and severity of acute rejection. | Transplantation 20010527 |
| FRAP-p70s6K signaling is required for pancreatic cancer cell proliferation. | The Journal of surgical research 20010515 |
| A calcineurin antagonist-free induction strategy for immunosuppression in cadaveric kidney transplant recipients at risk for delayed graft function. | Transplantation 20010515 |
| New drug development in non-Hodgkin lymphomas. | Current oncology reports 20010501 |
| Up-regulation of cell surface sodium channels by cyclosporin A, FK506, and rapamycin in adrenal chromaffin cells. | The Journal of pharmacology and experimental therapeutics 20010501 |
| Sanglifehrin A, a novel cyclophilin-binding immunosuppressant, inhibits IL-2-dependent T cell proliferation at the G1 phase of the cell cycle. | Journal of immunology (Baltimore, Md. : 1950) 20010501 |
| Pharmacokinetic interactions augment toxicities of sirolimus/cyclosporine combinations. | Journal of the American Society of Nephrology : JASN 20010501 |
| Flow-induced DNA synthesis requires signaling to a translational control pathway. | The Journal of surgical research 20010501 |
| Endotoxin (LPS) stimulates 4E-BP1/PHAS-I phosphorylation in macrophages. | The Journal of surgical research 20010501 |
| Dyslipidemia during sirolimus therapy in liver transplant recipients occurs with concomitant cyclosporine but not tacrolimus. | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010501 |
| Induction of differentiation of human myeloid leukemia cells by immunosuppressant macrolides (rapamycin and FK506) and calcium/calmodulin-dependent kinase inhibitors. | Experimental hematology 20010501 |
| Overview of side effects of immunosuppressive therapy. | Transplantation proceedings 20010501 |
| Assessment of mechanisms of action of immunosuppressive drugs using novel whole blood assays. | Transplantation proceedings 20010501 |
| Sirolimus and erythromycin interaction: two cases. | Transplantation proceedings 20010501 |
| Overview of clinical trials with new agents. | Transplantation proceedings 20010501 |
| Phase III trial of Rapamune versus placebo in primary renal allograft recipients. | Transplantation proceedings 20010501 |
| RAD reduces compensatory renal graft hypertrophy in a rat model of chronic rejection. | Transplantation proceedings 20010501 |
| FTY-720 is efficacious in monkey kidney transplantation. | Transplantation proceedings 20010501 |
| Adjunctive rapamycin and CsA treatment inhibits monocyte/macrophage associated cytokines/chemokines in sensitized cardiac graft recipients. | Transplantation 20010427 |
| p53/p21(CIP1) cooperate in enforcing rapamycin-induced G(1) arrest and determine the cellular response to rapamycin. | Cancer research 20010415 |
| Akt mediates insulin induction of glucose uptake and up-regulation of GLUT4 gene expression in brown adipocytes. | FEBS letters 20010413 |
| Rapamycin-insensitive regulation of 4e-BP1 in regenerating rat liver. | The Journal of biological chemistry 20010406 |
| Regulation of translation initiation by FRAP/mTOR. | Genes & development 20010401 |
| Liver transplantation using sirolimus and minimal corticosteroids (3-day taper). | Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 20010401 |
| Prevention of neointimal proliferation by immunosuppression in synthetic vascular grafts. | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20010401 |
| Review: uveitis and immunosuppressive drugs. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010401 |
| Signalling pathways regulating the dephosphorylation of Ser729 in the hydrophobic domain of protein kinase Cepsilon upon cell passage. | The Journal of biological chemistry 20010330 |
| The TOR kinases link nutrient sensing to cell growth. | The Journal of biological chemistry 20010330 |
| The cell survival signal Akt is differentially activated by PDGF-BB, EGF, and FGF-2 in osteoblastic cells. | Journal of cellular biochemistry 20010326 |
| [Prevention of instant restenosis after coronary angioplasty by implantation of rapamycin-coated stents]. | Ugeskrift for laeger 20010319 |
| The fission yeast TOR homolog, tor1+, is required for the response to starvation and other stresses via a conserved serine. | The Journal of biological chemistry 20010309 |
| Regulation of APG14 expression by the GATA-type transcription factor Gln3p. | The Journal of biological chemistry 20010302 |
| Involvement of both phosphatidylinositol 3-kinase and p44/p42 mitogen-activated protein kinase pathways in the short-term regulation of pyruvate kinase L by insulin. | Endocrinology 20010301 |
| Uncoupling p70(s6) kinase activation and proliferation: rapamycin-resistant proliferation of human CD8(+) T lymphocytes. | Journal of immunology (Baltimore, Md. : 1950) 20010301 |
| New immunosuppressive drugs: an update. | Current opinion in urology 20010301 |
| Failure of GPI compounds to display neurotrophic activity in vitro and in vivo. | European journal of pharmacology 20010301 |
| Use of sirolimus in kidney transplantation. | Progress in transplantation (Aliso Viejo, Calif.) 20010301 |
| Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog. | The Journal of antibiotics 20010301 |
| Treatment of transplant rejection: are the traditional immunosuppressants good enough? | Current opinion in investigational drugs (London, England : 2000) 20010301 |
| Translation initiation of the insulin-like growth factor I receptor mRNA is mediated by an internal ribosome entry site. | The Journal of biological chemistry 20010223 |
| Antitumor activity of the rapamycin analog CCI-779 in human primitive neuroectodermal tumor/medulloblastoma models as single agent and in combination chemotherapy. | Cancer research 20010215 |
| Overexpression of FK506-binding protein FKBP12.6 in cardiomyocytes reduces ryanodine receptor-mediated Ca(2+) leak from the sarcoplasmic reticulum and increases contractility. | Circulation research 20010202 |
| Impaired phosphate handling of renal allografts is aggravated under rapamycin-based immunosuppression. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010201 |
| The rapamycin sensitivity of human T-cell leukaemia virus type I-induced T-cell proliferation is mediated independently of the polypyrimidine motifs in the 5' long terminal repeat. | The Journal of general virology 20010201 |
| Solubilization of rapamycin. | International journal of pharmaceutics 20010201 |
| Sirolimus interferes with the innate response to bacterial products in human whole blood by attenuation of IL-10 production. | Scandinavian journal of immunology 20010201 |
| The flightless I protein colocalizes with actin- and microtubule-based structures in motile Swiss 3T3 fibroblasts: evidence for the involvement of PI 3-kinase and Ras-related small GTPases. | Journal of cell science 20010201 |
| Stent coatings. | The Journal of invasive cardiology 20010201 |
| 40-O-(2-hydroxyethyl)-rapamycin attenuates pulmonary arterial hypertension and neointimal formation in rats. | American journal of respiratory and critical care medicine 20010201 |
| [Effect of rapamycin on cytoplasmic accumulation of hetero nuclear ribonucleoprotein C-like unwinding protein 2]. | The Japanese journal of antibiotics 20010201 |
| A worldwide, phase III, randomized, controlled, safety and efficacy study of a sirolimus/cyclosporine regimen for prevention of acute rejection in recipients of primary mismatched renal allografts. | Transplantation 20010127 |
| Frap-dependent serine phosphorylation of IRS-1 inhibits IRS-1 tyrosine phosphorylation. | Biochemical and biophysical research communications 20010126 |
| [Rapamycin: a new immunosuppressive agent capable of inhibiting chronic rejection?]. | Casopis lekaru ceskych 20010119 |
| Lack of neointimal proliferation after implantation of sirolimus-coated stents in human coronary arteries: a quantitative coronary angiography and three-dimensional intravascular ultrasound study. | Circulation 20010116 |
| Insulin inhibits glucocorticoid-stimulated L-type 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase gene expression by activation of the c-Jun N-terminal kinase pathway. | The Biochemical journal 20010115 |
| Serotonin activates S6 kinase in a rapamycin-sensitive manner in Aplysia synaptosomes. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115 |
| Intracellular signals that control cell proliferation in mammalian balance epithelia: key roles for phosphatidylinositol-3 kinase, mammalian target of rapamycin, and S6 kinases in preference to calcium, protein kinase C, and mitogen-activated protein kinase. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115 |
| Pharmacokinetics and tolerability of 40-0-[2-hydroxyethyl]rapamycin in de novo liver transplant recipients. | Transplantation 20010115 |
| Regulation of glycogen synthesis by amino acids in cultured human muscle cells. | The Journal of biological chemistry 20010112 |
| Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells. | Biochemical and biophysical research communications 20010112 |
| Relative resistance in the development of T cell anergy in CD4+ T cells from simian immunodeficiency virus disease-resistant sooty mangabeys. | Journal of immunology (Baltimore, Md. : 1950) 20010101 |
| Counter-regulation of cytolytic activity and cytokine production in HIV-1-specific murine CD8+ cytotoxic T lymphocytes by free antigenic peptide. | International immunology 20010101 |
| Rapamycin in transplantation: a review of the evidence. | Kidney international 20010101 |
| Phosphatidylinositol-3,4,5-trisphosphate is required for insulin-like growth factor 1-mediated survival of 3T3-L1 preadipocytes. | Endocrinology 20010101 |
| Induction of the C/EBP homologous protein (CHOP) by amino acid deprivation requires insulin-like growth factor I, phosphatidylinositol 3-kinase, and mammalian target of rapamycin signaling. | Endocrinology 20010101 |
| Serine/threonine phosphorylation of IRS-1 triggers its degradation: possible regulation by tyrosine phosphorylation. | Diabetes 20010101 |
| Immunosuppressant use without bone loss--implications for bone loss after transplantation. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010101 |
| Pharmacokinetic interaction between single oral doses of diltiazem and sirolimus in healthy volunteers. | Clinical pharmacology and therapeutics 20010101 |
| Longitudinal assessment of everolimus in de novo renal transplant recipients over the first post-transplant year: pharmacokinetics, exposure-response relationships, and influence on cyclosporine. | Clinical pharmacology and therapeutics 20010101 |
| Sirolimus: a new promising immunosuppressive drug. Towards a rationale for its use in renal transplantation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101 |
| Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway. | RNA (New York, N.Y.) 20010101 |
| Immunosuppressive drugs in paediatric liver transplantation. | Paediatric drugs 20010101 |
| Rapamycin for GVHD prophylaxis--potential for severe myelotoxicity. | Bone marrow transplantation 20010101 |
| Involvement of p70 S6 kinase in bone morphogenetic protein signaling: vascular endothelial growth factor synthesis by bone morphogenetic protein-4 in osteoblasts. | Journal of cellular biochemistry 20010101 |
| Strategies for induction of clinical tolerance. | Transplantation proceedings 20010101 |
| Expression of MHC class II antigen is essential in tolerance induction by donor bone marrow cell in antilymphocyte serum-treated and rapamycin-treated mice. | Transplantation proceedings 20010101 |
| Induction of peripheral tolerance by posttransplant infusion of donor splenocytes. | Transplantation proceedings 20010101 |
| Addition of rapamycin to cyclosporine-prednisone based immunosuppression reduces the clinical risk of pretransplant anti-HLA antibody. | Transplantation proceedings 20010101 |
| Temporary treatment with sirolimus and low-trough cyclosporine prevents acute islet allograft rejection, and combination with starch-conjugated deferoxamine promotes islet engraftment in the preclinical pig model. | Transplantation proceedings 20010101 |
| Comparison of the in vitro metabolism of the macrolide immunosuppressants sirolimus and RAD. | Transplantation proceedings 20010101 |
| Rapamycin reduces expression of fibrosis-associated genes in an experimental model of renal ischaemia reperfusion injury. | Transplantation proceedings 20010101 |
| Donor pretreatment of grafts from marginal donors improves long-term graft outcome. | Transplantation proceedings 20010101 |
| Sirolimus is effective for prevention of acute rejection in primary mismatched renal allograft recipients. | Transplantation proceedings 20010101 |
| Sirolimus rescue therapy for refractory rejection in renal transplant recipients. | Transplantation proceedings 20010101 |
| Effect of rapamycin and FK506 on mesangial cell proliferation. | Transplantation proceedings 20010101 |
| Sirolimus-tacrolimus combination for combined kidney-pancreas transplantation: effect on renal function. | Transplantation proceedings 20010101 |
| Sirolimus does not potentiate indices of chronic cyclosporin nephrotoxicity. | Transplantation proceedings 20010101 |
| A single-center open label randomized trial of the safety and efficacy of the use of sirolimus versus azathioprine in one-haplotype living related kidney transplant recipients-preliminary results. | Transplantation proceedings 20010101 |
| Cyclosporine and tacrolimus alter renin-angiotesin system in mouse medullary-thick ascending limb cultured cells. | Transplantation proceedings 20010101 |
| Rescue therapy: a role for sirolimus in lung and heart transplant recipients. | Transplantation proceedings 20010101 |
| Pharmacokinetic interactions between sirolimus and cyclosporine exacerbate renal dysfunction. | Transplantation proceedings 20010101 |
| Fast quantification method for sirolimus and its major metabolites. | Transplantation proceedings 20010101 |
| Impact of sirolimus on renal transplant outcomes in African Americans. | Transplantation proceedings 20010101 |
| Sirolimus permits steroid withdrawal from a cyclosporine regimen. | Transplantation proceedings 20010101 |
| Therapeutic drug monitoring of sirolimus for optimal renal transplant outcomes. | Transplantation proceedings 20010101 |
| De novo use of low-dose tacrolimus and sirolimus in liver transplantation. | Transplantation proceedings 20010101 |
| Sirolimus (rapamycin)-based rescue treatment following chronic rejection after liver transplantation. | Transplantation proceedings 20010101 |
| Rapamycin blocks IL-2-driven T cell cycle progression while preserving T cell survival. | Blood cells, molecules & diseases 20010101 |
| Influence of cyclosporin, tacrolimus and rapamycin on renal function and arterial hypertension after renal transplantation. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010101 |
| Rapamycin reduces hybridoma cell death and enhances monoclonal antibody production. | Biotechnology and bioengineering 20010101 |
| High-throughput semi-automated 96-well liquid/liquid extraction and liquid chromatography/mass spectrometric analysis of everolimus (RAD 001) and cyclosporin a (CsA) in whole blood. | Rapid communications in mass spectrometry : RCM 20010101 |
| Protein tyrosine kinase-dependent regulation of adenylate cyclase and phosphatidylinositol 3-kinase activates the expression of glial fibrillary acidic protein upon induction of differentiation in rat c6 glioma. | Cell biology international 20010101 |
| Methods and assays to investigate nuclear export. | Current topics in microbiology and immunology 20010101 |
| HPLC assay with ultraviolet detection for therapeutic drug monitoring of sirolimus. | Clinical chemistry 20010101 |
| A new vascularized adrenal transplantation model in the rat. | Microsurgery 20010101 |
| Adverse gastrointestinal effects of mycophenolate mofetil: aetiology, incidence and management. | Drug safety 20010101 |
| Clinical pharmacokinetics of sirolimus. | Clinical pharmacokinetics 20010101 |
| Control of translation by the target of rapamycin proteins. | Progress in molecular and subcellular biology 20010101 |
| Regulation of protein synthesis by insulin through IRS-1. | Progress in molecular and subcellular biology 20010101 |
| The evolving role of tor inhibitors for individualizing posttransplant immunosuppression. | Transplantation proceedings 20010101 |
| Abbreviated cyclosporine pharmacokinetic profiling in clinical renal transplantation: from principles to practice. | Transplantation proceedings 20010101 |
| The role of Certican (everolimus, rad) in the many pathways of chronic rejection. | Transplantation proceedings 20010101 |
| Rapamycin reduces rejection in heart transplant recipients. | Transplantation proceedings 20010101 |
| Sirolimus and low-dose tacrolimus with antibody induction in kidney transplantation: preliminary results of a pilot study. | Transplantation proceedings 20010101 |
| Low-dose sirolimus and tacrolimus in kidney transplantation: first results of a single-center experience. | Transplantation proceedings 20010101 |
| Low-dose immunosuppression with FK 506 and sirolimus after liver transplantation: 1-year results. | Transplantation proceedings 20010101 |
| A pilot study of steroid withdrawal from kidney transplant recipients on sirolimus-cyclosporine a combination therapy. | Transplantation proceedings 20010101 |
| Conversion to rapamycin in renal allograft recipients with biopsy-proven calcineurin inhibitor-induced nephrotoxicity. | Transplantation proceedings 20010101 |
| De novo hemolytic uremic syndrome after kidney transplantation in patients treated with cyclosporine a sirolimus combination. | Transplantation proceedings 20010101 |
| Effect of ERL080A, RAD, and Neoral on hamster-to-rat heart xenograft survival. | Transplantation proceedings 20010101 |
| Stent development and local drug delivery. | British medical bulletin 20010101 |
| [New developments in immunosuppressive therapy]. | Kongressband. Deutsche Gesellschaft fur Chirurgie. Kongress 20010101 |
| Resistance to rapamycin: a novel anticancer drug. | Cancer metastasis reviews 20010101 |
| [Toward an evidence-based immunosuppression]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20010101 |
| Secondary metabolism in simulated microgravity. | Chemical record (New York, N.Y.) 20010101 |
| Anaerobic growth of Saccharomyces cerevisiae alleviates the lethal effect of phosphotyrosyl phosphatase activators depletion. | Acta biochimica Polonica 20010101 |
| The drug-eluting stent: is it the Holy Grail? | Reviews in cardiovascular medicine 20010101 |
| Conversion to rapamycin immunosuppression in renal transplant recipients: report of an initial experience. | Transplantation 20001027 |
| Specificity and mechanism of action of some commonly used protein kinase inhibitors. | The Biochemical journal 20001001 |
| Endothelin-1 as a protective factor against beta-adrenergic agonist-induced apoptosis in cardiac myocytes. | Journal of the American College of Cardiology 20001001 |
| Stem cell factor/c-kit up-regulates cyclin D3 and promotes cell cycle progression via the phosphoinositide 3-kinase/p70 S6 kinase pathway in spermatogonia. | The Journal of biological chemistry 20000818 |
| Antifungal rapamycin analogues with reduced immunosuppressive activity. | Bioorganic & medicinal chemistry letters 20000703 |
| Sirolimus: a new agent for prevention of renal allograft rejection. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20000301 |
| Sirolimus in pediatric gastrointestinal transplantation: the use of sirolimus for pediatric transplant patients with tacrolimus-related cardiomyopathy. | Pediatric transplantation 20000201 |
| Rapamycin inhibits hepatic stellate cell proliferation in vitro and limits fibrogenesis in an in vivo model of liver fibrosis. | Gastroenterology 19991101 |
| A phase I study of a 4-week course of SDZ-RAD (RAD) quiescent cyclosporine-prednisone-treated renal transplant recipients. | Transplantation 19991027 |
| Antifungal activities of antineoplastic agents: Saccharomyces cerevisiae as a model system to study drug action. | Clinical microbiology reviews 19991001 |
| Cellular stress in xenopus kidney cells enhances the phosphorylation of eukaryotic translation initiation factor (eIF)4E and the association of eIF4F with poly(A)-binding protein. | The Biochemical journal 19990915 |
| Neuronal survival activity of s100betabeta is enhanced by calcineurin inhibitors and requires activation of NF-kappaB. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 19990901 |
| p70(s6k) integrates phosphatidylinositol 3-kinase and rapamycin-regulated signals for E2F regulation in T lymphocytes. | Molecular and cellular biology 19990701 |
| Rapamycin inhibits didemnin B-induced apoptosis in human HL-60 cells: evidence for the possible involvement of FK506-binding protein 25. | Immunology and cell biology 19990601 |
| Systemic toxicity following administration of sirolimus (formerly rapamycin) for psoriasis: association of capillary leak syndrome with apoptosis of lesional lymphocytes. | Archives of dermatology 19990501 |
| Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group. | Transplantation 19990415 |
| The FKBP12-rapamycin-binding domain is required for FKBP12-rapamycin-associated protein kinase activity and G1 progression. | The Journal of biological chemistry 19990212 |
| Immunophilins: beyond immunosuppression. | Journal of medicinal chemistry 19981217 |
| Regulation of System A amino acid transport in L6 rat skeletal muscle cells by insulin, chemical and hyperthermic stress. | FEBS letters 19981211 |
| Expression and regulation of neuronal apoptosis inhibitory protein during adipocyte differentiation. | Diabetes 19981201 |
| Ascomycin macrolactam derivative SDZ ASM 981 inhibits the release of granule-associated mediators and of newly synthesized cytokines in RBL 2H3 mast cells in an immunophilin-dependent manner. | Archives of dermatological research 19980901 |
| Chemical modification of rapamycin: the discovery of SDZ RAD. | Transplantation proceedings 19980801 |
| Protective effects of FK506 against glutamate-induced neurotoxicity in retinal cell culture. | Investigative ophthalmology & visual science 19980601 |
| Antifungal activities of rapamycin and its derivatives, prolylrapamycin, 32-desmethylrapamycin, and 32-desmethoxyrapamycin. | The Journal of antibiotics 19980501 |
| Radiosensitization of human tumor cells by the phosphatidylinositol3-kinase inhibitors wortmannin and LY294002 correlates with inhibition of DNA-dependent protein kinase and prolonged G2-M delay. | Clinical cancer research : an official journal of the American Association for Cancer Research 19970701 |
| Rapamycin (sirolimus) inhibits proliferating cell nuclear antigen expression and blocks cell cycle in the G1 phase in human keratinocyte stem cells. | The Journal of clinical investigation 19970501 |
| Novel anti-Pneumocystis carinii effects of the immunosuppressant mycophenolate mofetil in contrast to provocative effects of tacrolimus, sirolimus, and dexamethasone. | The Journal of infectious diseases 19970401 |
| Sirolimus, a new, potent immunosuppressive agent. | Pharmacotherapy 19970101 |
| Rapamycin stimulates viral protein synthesis and augments the shutoff of host protein synthesis upon picornavirus infection. | Journal of virology 19961201 |
| Comparison of acute rapamycin nephrotoxicity with cyclosporine and FK506. | Kidney international 19961001 |
| Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. | The EMBO journal 19960201 |
| Modulators and substrates of P-glycoprotein and cytochrome P4503A coordinately up-regulate these proteins in human colon carcinoma cells. | Molecular pharmacology 19960201 |
| Rapamycin inhibits the in vitro release of soluble interleukin-2 receptor by activated peripheral blood mononuclear cells (PBMC) independently of the mode of activation. | International journal of immunopharmacology 19950701 |
| Identification of an 11-kDa FKBP12-rapamycin-binding domain within the 289-kDa FKBP12-rapamycin-associated protein and characterization of a critical serine residue. | Proceedings of the National Academy of Sciences of the United States of America 19950523 |
| Rapamycin-FKBP inhibits cell cycle regulators of proliferation in vascular smooth muscle cells. | Circulation research 19950301 |
| Nephrotoxicity of cyclosporin A and FK506: inhibition of calcineurin phosphatase. | Renal physiology and biochemistry 19950101 |
| RAPT1, a mammalian homolog of yeast Tor, interacts with the FKBP12/rapamycin complex. | Proceedings of the National Academy of Sciences of the United States of America 19941220 |
| Nephrotoxicity of immunosuppressants in rats: comparison of macrolides with cyclosporin. | Experimental nephrology 19940101 |
| Rapamycin-FKBP12 blocks proliferation, induces differentiation, and inhibits cdc2 kinase activity in a myogenic cell line. | The Journal of biological chemistry 19931205 |
| Rapamycin blocks cell cycle progression of activated T cells prior to events characteristic of the middle to late G1 phase of the cycle. | Journal of cellular physiology 19930101 |
| Immunosuppressants FK506 and rapamycin function as reversal agents of the multidrug resistance phenotype. | Blood 19920915 |
| Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase. | Nature 19920702 |
| Rapamycin and FK506 differentially inhibit mast cell cytokine production and cytokine-induced proliferation and act as reciprocal antagonists. | The Journal of pharmacology and experimental therapeutics 19920601 |
| Calcineurin phosphatase activity in T lymphocytes is inhibited by FK 506 and cyclosporin A. | Proceedings of the National Academy of Sciences of the United States of America 19920501 |
| Effects of steroids and immunosuppressive drugs on endotoxin-uveitis in rabbits. | Journal of ocular pharmacology 19920101 |
| Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. | Cell 19910823 |
| The effect of the immunosuppressant FK-506 on alternate pathways of T cell activation. | European journal of immunology 19910201 |
| Calcineurin primes immature gonadotropin-releasing hormone-secreting neuroendocrine cells for migration. | Molecular endocrinology (Baltimore, Md.) |
| Chronic inhibition of the mTORC1/S6K1 pathway increases insulin-induced PI3K activity but inhibits Akt2 and glucose transport stimulation in 3T3-L1 adipocytes. | Molecular endocrinology (Baltimore, Md.) |