Home Other Building Blocks 2-oxopropanal, 40% in water

2-oxopropanal, 40% in water

CAS No.:
78-98-8
Catalog Number:
AG0035K2
Molecular Formula:
C3H4O2
Molecular Weight:
72.0627
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
40%
In Stock USA
United States
$13
- +
25g
40%
In Stock USA
United States
$25
- +
100g
40%
In Stock USA
United States
$63
- +
500g
40%
In Stock USA
United States
$188
- +
Product Description
Catalog Number:
AG0035K2
Chemical Name:
2-oxopropanal, 40% in water
CAS Number:
78-98-8
Molecular Formula:
C3H4O2
Molecular Weight:
72.0627
MDL Number:
MFCD00006960
IUPAC Name:
2-oxopropanal
InChI:
InChI=1S/C3H4O2/c1-3(5)2-4/h2H,1H3
InChI Key:
AIJULSRZWUXGPQ-UHFFFAOYSA-N
SMILES:
O=CC(=O)C
EC Number:
201-164-8
UNII:
722KLD7415
FEMA Number:
2969
UN Number:
1993
Properties
Complexity:
55.9  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
72.021g/mol
Formal Charge:
0
Heavy Atom Count:
5  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
72.063g/mol
Monoisotopic Mass:
72.021g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
34.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.4  
Literature
Title Journal
Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury. Toxicology letters 20180915
Limonene protects osteoblasts against methylglyoxal-derived adduct formation by regulating glyoxalase, oxidative stress, and mitochondrial function. Chemico-biological interactions 20171225
Magnolol protects pancreatic β-cells against methylglyoxal-induced cellular dysfunction. Chemico-biological interactions 20171101
Hepatoprotective effect of 7-Hydroxycoumarin against Methyl glyoxal toxicity via activation of Nrf2. Chemico-biological interactions 20171001
Reactive carbonyl compounds impair wound healing by vimentin collapse and loss of the primary cilium. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20171001
Receptor for advanced glycation end products (RAGE) knockout reduces fetal dysmorphogenesis in murine diabetic pregnancy. Reproductive toxicology (Elmsford, N.Y.) 20160701
Non-enzymatic modifications of prostaglandin H synthase 1 affect bifunctional enzyme activity - Implications for the sensitivity of blood platelets to acetylsalicylic acid. Chemico-biological interactions 20160625
Protective effects of honokiol against methylglyoxal-induced osteoblast damage. Chemico-biological interactions 20160125
Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells. Chemico-biological interactions 20151205
Neuroprotective effect of sulforaphane against methylglyoxal cytotoxicity. Chemical research in toxicology 20150615
Nrf2-mediated adaptive response to methyl glyoxal in HepG2 cells involves the induction of AKR7A2. Chemico-biological interactions 20150605
Inhibitory effect of apocynin on methylglyoxal-mediated glycation in osteoblastic MC3T3-E1 cells. Journal of applied toxicology : JAT 20150401
Fatty acids binding to human serum albumin: Changes of reactivity and glycation level of Cysteine-34 free thiol group with methylglyoxal. Chemico-biological interactions 20141205
Effects of methylglyoxal and pyridoxamine in rat brain mitochondria bioenergetics and oxidative status. Journal of bioenergetics and biomembranes 20141001
Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells. Toxicology in vitro : an international journal published in association with BIBRA 20140601
Methylglyoxal (MG) and cerebro-renal interaction: does long-term orally administered MG cause cognitive impairment in normal Sprague-Dawley rats? Toxins 20140101
A novel natural Nrf2 activator with PPARγ-agonist (monascin) attenuates the toxicity of methylglyoxal and hyperglycemia. Toxicology and applied pharmacology 20131101
Resveratrol protects against methylglyoxal-induced apoptosis and disruption of embryonic development in mouse blastocysts. Environmental toxicology 20130801
Glyoxal and methylglyoxal: autoxidation from dihydroxyacetone and polyphenol cytoprotective antioxidant mechanisms. Chemico-biological interactions 20130225
Effects of monascin on anti-inflammation mediated by Nrf2 activation in advanced glycation end product-treated THP-1 monocytes and methylglyoxal-treated wistar rats. Journal of agricultural and food chemistry 20130213
A nonradioisotope chemiluminescent assay for evaluation of 2-deoxyglucose uptake in 3T3-L1 adipocytes. Effect of various carbonyls species on insulin action. Biochimie 20121201
Effect of high hydrostatic pressure on antimicrobial activity and quality of Manuka honey. Food chemistry 20121201
Voltammetric detection of the α-dicarbonyl compound: methylglyoxal as a flavoring agent in wine and beer. Analytica chimica acta 20121102
Exogenous selenium pretreatment protects rapeseed seedlings from cadmium-induced oxidative stress by upregulating antioxidant defense and methylglyoxal detoxification systems. Biological trace element research 20121101
Lipidome analysis in multiple sclerosis reveals protein lipoxidative damage as a potential pathogenic mechanism. Journal of neurochemistry 20121101
Antioxidant content and activity of the Indian fresh-water pearl mussel in the prevention of arthritis in an experimental animal model. The British journal of nutrition 20121028
Skin beautification with oral non-hydrolized versions of carnosine and carcinine: Effective therapeutic management and cosmetic skincare solutions against oxidative glycation and free-radical production as a causal mechanism of diabetic complications and skin aging. The Journal of dermatological treatment 20121001
Catalase, a target of glycation damage in rat liver mitochondria with aging. Biochimica et biophysica acta 20121001
Carbonyl stress and a combination of astaxanthin/vitamin C induce biochemical changes in human neutrophils. Toxicology in vitro : an international journal published in association with BIBRA 20121001
Targeting the glyoxalase pathway enhances TRAIL efficacy in cancer cells by downregulating the expression of antiapoptotic molecules. Molecular cancer therapeutics 20121001
Whole globe inflation testing of exogenously crosslinked sclera using genipin and methylglyoxal. Experimental eye research 20121001
Development of a method for the determination of advanced glycation end products precursors by liquid chromatography and its application in human urine samples. Journal of separation science 20121001
The glyoxalase pathway in protozoan parasites. International journal of medical microbiology : IJMM 20121001
An initial investigation into the anti-inflammatory activity and antioxidant capacity of alpha-cyclodextrin-complexed Manuka honey. Journal of complementary & integrative medicine 20120924
Resveratrol upregulates Nrf2 expression to attenuate methylglyoxal-induced insulin resistance in Hep G2 cells. Journal of agricultural and food chemistry 20120912
Impaired drug-binding capacities of in vitro and in vivo glycated albumin. Biochimie 20120901
Carbonylation induces heterogeneity in cardiac ryanodine receptor function in diabetes mellitus. Molecular pharmacology 20120901
The role of endothelial cell adhesion molecules P-selectin, E-selectin and intercellular adhesion molecule-1 in leucocyte recruitment induced by exogenous methylglyoxal. Immunology 20120901
Anti-glycative and anti-inflammatory effects of protocatechuic acid in brain of mice treated by D-galactose. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120901
Trapping of methylglyoxal by curcumin in cell-free systems and in human umbilical vein endothelial cells. Journal of agricultural and food chemistry 20120822
Possible link between the cognitive dysfunction associated with diabetes mellitus and the neurotoxicity of methylglyoxal. Brain research 20120821
Methylglyoxal activates nociceptors through transient receptor potential channel A1 (TRPA1): a possible mechanism of metabolic neuropathies. The Journal of biological chemistry 20120817
Anti-oxidative, anti-glycative and anti-apoptotic effects of oleanolic acid in brain of mice treated by D-galactose. European journal of pharmacology 20120815
Dual effect of methylglyoxal on the intracellular Ca2+ signaling and neurite outgrowth in mouse sensory neurons. Cellular and molecular neurobiology 20120801
Decarboxylation mechanisms in biological system. Bioorganic chemistry 20120801
Breast cancer proteomics reveals a positive correlation between glyoxalase 1 expression and high tumor grade. International journal of oncology 20120801
Methylglyoxal inhibition of cytosolic ascorbate peroxidase from Nicotiana tabacum. Journal of biochemical and molecular toxicology 20120801
Glycation and insulin resistance: novel mechanisms and unique targets? Arteriosclerosis, thrombosis, and vascular biology 20120801
Reactive carbonyl compounds (RCCs) cause aggregation and dysfunction of fibrinogen. Protein & cell 20120801
Glyoxalase I (GLO1) is up-regulated in pancreatic cancerous tissues compared with related non-cancerous tissues. Anticancer research 20120801
[The biological reaction of inflammation, methylglyoxal of blood plasma, functional and structural alterations in elastic type arteries at the early stage of hypertension disease]. Klinicheskaia laboratornaia diagnostika 20120801
Classification and characterization of manuka honeys based on phenolic compounds and methylglyoxal. Journal of agricultural and food chemistry 20120725
Gene silencing of the mitochondrial adaptor p66(Shc) suppresses vascular hyperglycemic memory in diabetes. Circulation research 20120720
1,2-dicarbonyl compounds in commonly consumed foods. Journal of agricultural and food chemistry 20120718
Human DJ-1 and its homologs are novel glyoxalases. Human molecular genetics 20120715
Aristolochic acid-induced accumulation of methylglyoxal and Nε-(carboxymethyl)lysine: an important and novel pathway in the pathogenic mechanism for aristolochic acid nephropathy. Biochemical and biophysical research communications 20120713
N-acetylcysteine reduces oxidative stress in sickle cell patients. Annals of hematology 20120701
Identification and quantification of six major α-dicarbonyl process contaminants in high-fructose corn syrup. Analytical and bioanalytical chemistry 20120701
Methylglyoxal-induced stomatal closure accompanied by peroxidase-mediated ROS production in Arabidopsis. Journal of plant physiology 20120701
Ambiguous effect of dendrimer PAMAM G3 on rat heart respiration in a model of an experimental diabetes - Objective causes of laboratory misfortune or unpredictable G3 activity? International journal of pharmaceutics 20120701
Arginine attenuates methylglyoxal- and high glucose-induced endothelial dysfunction and oxidative stress by an endothelial nitric-oxide synthase-independent mechanism. The Journal of pharmacology and experimental therapeutics 20120701
A quick, convenient and economical method for the reliable determination of methylglyoxal in millimolar concentrations: the N-acetyl-L-cysteine assay. Analytical and bioanalytical chemistry 20120701
Tight-binding inhibitors efficiently inactivate both reaction centers of monomeric Plasmodium falciparum glyoxalase 1. The FEBS journal 20120701
Stereospecificity of (1) H, (13) C and (15) N shielding constants in the isomers of methylglyoxal bisdimethylhydrazone: problem with configurational assignment based on (1) H chemical shifts. Magnetic resonance in chemistry : MRC 20120701
Degradation of bacterial DNA by a natural antimicrobial agent with the help of biomimetic membrane system. Indian journal of experimental biology 20120701
Unusually fast 1,6-h shifts of enolic hydrogens in peroxy radicals: formation of the first-generation C2 and C3 carbonyls in the oxidation of isoprene. The journal of physical chemistry. A 20120621
Investigation of aqueous-phase photooxidation of glyoxal and methylglyoxal by aerosol chemical ionization mass spectrometry: observation of hydroxyhydroperoxide formation. The journal of physical chemistry. A 20120621
Laboratory kinetic and mechanistic studies on the OH-initiated oxidation of acetone in aqueous solution. The journal of physical chemistry. A 20120621
Diabetes: Methylglyoxal mediates hyperalgesia in patients with painful diabetic neuropathy. Nature reviews. Neurology 20120612
Flavour chemistry of methylglyoxal and glyoxal. Chemical Society reviews 20120607
Reaction of methacrolein with the hydroxyl radical in air: incorporation of secondary O2 addition into the MACR + OH master equation. The journal of physical chemistry. A 20120607
A short review on creatine-creatine kinase system in relation to cancer and some experimental results on creatine as adjuvant in cancer therapy. Amino acids 20120601
Exogenous collagen cross-linking recovers tendon functional integrity in an experimental model of partial tear. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20120601
Methylglyoxal-induced modifications of significant honeybee proteinous components in manuka honey: Possible therapeutic implications. Fitoterapia 20120601
Varying amounts of different aldehydes present in the cryoprotectants dimethyl sulphoxide and 1,2-propanediol. Cryobiology 20120601
Mycobacterium tuberculosis Rv0577, a novel TLR2 agonist, induces maturation of dendritic cells and drives Th1 immune response. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120601
Mitochondrial involvement to methylglyoxal detoxification: D-Lactate/Malate antiporter in Saccharomyces cerevisiae. Antonie van Leeuwenhoek 20120601
Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease. Clinical journal of the American Society of Nephrology : CJASN 20120601
Dke1--structure, dynamics, and function: a theoretical and experimental study elucidating the role of the binding site shape and the hydrogen-bonding network in catalysis. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20120601
Methylglyoxal modification of Nav1.8 facilitates nociceptive neuron firing and causes hyperalgesia in diabetic neuropathy. Nature medicine 20120601
Glyoxalase 1 increases anxiety by reducing GABAA receptor agonist methylglyoxal. The Journal of clinical investigation 20120601
Cigarette smoke enhances chemotaxis via acetylation of proline-glycine-proline. Frontiers in bioscience (Elite edition) 20120601
Exploring post-translational arginine modification using chemically synthesized methylglyoxal hydroimidazolones. Journal of the American Chemical Society 20120530
Rapid and sensitive determination of the intermediates of advanced glycation end products in the human nail by ultra-performance liquid chromatography with electrospray ionization time-of-flight mass spectrometry. Analytical biochemistry 20120515
Impact of the N-terminal amino acid on the formation of pyrazines from peptides in Maillard model systems. Journal of agricultural and food chemistry 20120509
Evaluating genetic markers and neurobiochemical analytes for fluoxetine response using a panel of mouse inbred strains. Psychopharmacology 20120501
Gliclazide may have an antiapoptotic effect related to its antioxidant properties in human normal and cancer cells. Molecular biology reports 20120501
Methylglyoxal induces hyperpermeability of the blood-retinal barrier via the loss of tight junction proteins and the activation of matrix metalloproteinases. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20120501
Methylglyoxal causes structural and functional alterations in adipose tissue independently of obesity. Archives of physiology and biochemistry 20120501
Methylglyoxal promotes oxidative stress and endothelial dysfunction. Pharmacological research 20120501
The missing link in coenzyme A biosynthesis: PanM (formerly YhhK), a yeast GCN5 acetyltransferase homologue triggers aspartate decarboxylase (PanD) maturation in Salmonella enterica. Molecular microbiology 20120501
Regulation of proline metabolism in mycobacteria and its role in carbon metabolism under hypoxia. Molecular microbiology 20120501
Optical properties of the products of α-dicarbonyl and amine reactions in simulated cloud droplets. Environmental science & technology 20120501
Short communication: Evidence for methylglyoxal-mediated browning of Parmesan cheese during low temperature storage. Journal of dairy science 20120501
Reconstruction of genome-scale active metabolic networks for 69 human cell types and 16 cancer types using INIT. PLoS computational biology 20120501
Study on the changes of carbonic anhydrase activity in insulin resistance and the effect of methylglyoxal. JPMA. The Journal of the Pakistan Medical Association 20120501
Chromatographic determination of methyl glyoxal in blood plasma as the test for glycotoxicity and accumulation of glycation end-products. Bulletin of experimental biology and medicine 20120501
Discovering protein-based inheritance through yeast genetics. The Journal of biological chemistry 20120427
Inhibition of advanced glycation end product formation by Pu-erh tea ameliorates progression of experimental diabetic nephropathy. Journal of agricultural and food chemistry 20120425
[The role of methylglyoxal metabolism in type-2 diabetes and its complications]. Orvosi hetilap 20120415
Cavity closure dynamics of peracetylated β-cyclodextrins in supercritical carbon dioxide. The journal of physical chemistry. B 20120405
Advanced glycation endproducts and their pathogenic roles in neurological disorders. Amino acids 20120401
Advanced glycation endproducts: from precursors to RAGE: round and round we go. Amino acids 20120401
Lipid glycation and protein glycation in diabetes and atherosclerosis. Amino acids 20120401
Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics. Amino acids 20120401
Methylglyoxal, glyoxalase 1 and the dicarbonyl proteome. Amino acids 20120401
Theoretical studies on models of lysine-arginine cross-links derived from α-oxoaldehydes: a new mechanism for glucosepane formation. Journal of molecular modeling 20120401
Occurrence and distribution of salsolinol-like compound, 1-acetyl-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline (ADTIQ) in parkinsonian brains. Journal of neural transmission (Vienna, Austria : 1996) 20120401
Transcriptional control of glyoxalase 1 by Nrf2 provides a stress-responsive defence against dicarbonyl glycation. The Biochemical journal 20120401
Two alanine aminotranferases link mitochondrial glycolate oxidation to the major photorespiratory pathway in Arabidopsis and rice. Journal of experimental botany 20120401
Physiological and proteomic approaches to address the active role of ozone in kiwifruit post-harvest ripening. Journal of experimental botany 20120401
Is diabetes an acquired disorder of reactive glucose metabolites and their intermediates? Diabetologia 20120401
Methylglyoxal, advanced glycation end products and autism: is there a connection? Medical hypotheses 20120401
Structural modifications of human albumin in diabetes. Diabetes & metabolism 20120401
Glutathione peroxidase inhibitory assay for electrophilic pollutants in diesel exhaust and tobacco smoke. Analytical and bioanalytical chemistry 20120401
Structure of Escherichia coli aspartate α-decarboxylase Asn72Ala: probing the role of Asn72 in pyruvoyl cofactor formation. Acta crystallographica. Section F, Structural biology and crystallization communications 20120401
Nephrotoxin-induced renal cell injury involving biochemical alterations and its prevention with antioxidant. Journal of clinical medicine research 20120401
Postprandial impairment of flow-mediated dilation and elevated methylglyoxal after simple but not complex carbohydrate consumption in dogs. Nutrition research (New York, N.Y.) 20120401
Comparative DFT study to determine if α-oxoaldehydes are precursors for pentosidine formation. The journal of physical chemistry. A 20120322
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis. The EMBO journal 20120321
Potential of a γ-glutamyl-transpeptidase-stable glutathione analogue against amyloid-β toxicity. ACS chemical neuroscience 20120321
Cathepsins D and L reduce the toxicity of advanced glycation end products. Free radical biology & medicine 20120315
γ-Tocopherol abolishes postprandial increases in plasma methylglyoxal following an oral dose of glucose in healthy, college-aged men. The Journal of nutritional biochemistry 20120301
A53T-alpha-synuclein-overexpression in the mouse nigrostriatal pathway leads to early increase of 14-3-3 epsilon and late increase of GFAP. Journal of neural transmission (Vienna, Austria : 1996) 20120301
Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology. Diabetologia 20120301
Ni2+-activated glyoxalase I from Escherichia coli: substrate specificity, kinetic isotope effects and evolution within the βαβββ superfamily. Journal of inorganic biochemistry 20120301
Protection from diabetes-induced peripheral sensory neuropathy--a role for elevated glyoxalase I? Experimental neurology 20120301
Use of denuder/filter apparatus to investigate terpene ozonolysis. Journal of environmental monitoring : JEM 20120301
Different response of body weight change according to ketonuria after fasting in the healthy obese. Journal of Korean medical science 20120301
New Zealand kanuka honey has high levels of methylglyoxal and antimicrobial activity. Journal of alternative and complementary medicine (New York, N.Y.) 20120301
Oxidative modification of ferritin induced by methylglyoxal. BMB reports 20120301
Opportunistic parasites among immunosuppressed children in Minia District, Egypt. The Korean journal of parasitology 20120301
Accumulation of argpyrimidine, a methylglyoxal-derived advanced glycation end product, increases apoptosis of lens epithelial cells both in vitro and in vivo. Experimental & molecular medicine 20120227
The overall reaction process of ozone with methacrolein and isoprene in the condensed phase. The journal of physical chemistry. A 20120223
Organocatalytic enantioselective synthesis of 2,3-dihydropyridazines. Chemical communications (Cambridge, England) 20120218
Ellagic acid, a new antiglycating agent: its inhibition of Nϵ-(carboxymethyl)lysine. The Biochemical journal 20120215
Phlorotannins from brown algae (Fucus vesiculosus) inhibited the formation of advanced glycation endproducts by scavenging reactive carbonyls. Journal of agricultural and food chemistry 20120208
Photoexcited tautomerization of vinyl alcohol to acetylaldehyde via a conical intersection from contracted Schrödinger theory. Physical chemistry chemical physics : PCCP 20120207
Effect of coffee filtrate, methylglyoxal, glyoxal, and caffeine on Salmonella typhimurium and S. enteritidis survival in ground chicken breasts. Journal of food science 20120201
pPKCα mediated-HIF-1α activation related to the morphological modifications occurring in neonatal myocardial tissue in response to severe and mild hyperoxia. European journal of histochemistry : EJH 20120120
Formation of early and advanced Maillard reaction products correlates to the ripening of cheese. Journal of agricultural and food chemistry 20120118
Increased glyoxalase I levels inhibit accumulation of oxidative stress and an advanced glycation end product in mouse mesangial cells cultured in high glucose. Experimental cell research 20120115
Human aldo-keto reductase AKR7A2 protects against the cytotoxicity and mutagenicity of reactive aldehydes and lowers intracellular reactive oxygen species in hamster V79-4 cells. Chemico-biological interactions 20120105
Epigallocatechin gallate suppresses peritoneal fibrosis in mice. Chemico-biological interactions 20120105
Reduction of glucose uptake through inhibition of hexose transporters and enhancement of their endocytosis by methylglyoxal in Saccharomyces cerevisiae. The Journal of biological chemistry 20120102
'NEPP' peritoneal dialysis regimen has beneficial effects on plasma CEL and 3-DG, but not pentosidine, CML, and MGO. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20120101
High levels of IgM against methylglyoxal-modified apolipoprotein B100 are associated with less coronary artery calcification in patients with type 2 diabetes. Journal of internal medicine 20120101
Beneficial effect of traditional chinese medicinal formula danggui-shaoyao-san on advanced glycation end-product-mediated renal injury in streptozotocin-diabetic rats. Evidence-based complementary and alternative medicine : eCAM 20120101
Long-term methylglyoxal treatment impairs smooth muscle contractility in organ-cultured rat mesenteric artery. Pharmacological research 20120101
Antioxidant and anti-inflammatory effects of exercise in diabetic patients. Experimental diabetes research 20120101
Antibacterial components of honey. IUBMB life 20120101
Cloning and characterization of AKR4C14, a rice aldo-keto reductase, from Thai Jasmine rice. The protein journal 20120101
Regulation of RAGE for attenuating progression of diabetic vascular complications. Experimental diabetes research 20120101
Leukocyte adhesion molecules in diabetic retinopathy. Journal of ophthalmology 20120101
Inhibiting TRPA1 ion channel reduces loss of cutaneous nerve fiber function in diabetic animals: sustained activation of the TRPA1 channel contributes to the pathogenesis of peripheral diabetic neuropathy. Pharmacological research 20120101
Chemical and physiological relevance of glucose degradation products in peritoneal dialysis. Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation 20120101
Engineered Trx2p industrial yeast strain protects glycolysis and fermentation proteins from oxidative carbonylation during biomass propagation. Microbial cell factories 20120101
Lignin is linked to ethyl-carbamate formation in ume (Prunus mume) liqueur. Bioscience, biotechnology, and biochemistry 20120101
Cellular dysfunction in diabetes as maladaptive response to mitochondrial oxidative stress. Experimental diabetes research 20120101
Long-term survival of hydrated resting eggs from Brachionus plicatilis. PloS one 20120101
Hydroimidazolone modification of the conserved Arg12 in small heat shock proteins: studies on the structure and chaperone function using mutant mimics. PloS one 20120101
Environmental factors affecting the expression of pilAB as well as the proteome and transcriptome of the grass endophyte Azoarcus sp. strain BH72. PloS one 20120101
The role of methylglyoxal-modified proteins in gastric ulcer healing. Current medicinal chemistry 20120101
Astroglial pentose phosphate pathway rates in response to high-glucose environments. ASN neuro 20120101
Markov Chain Ontology Analysis (MCOA). BMC bioinformatics 20120101
Role of the HaHOG1 MAP kinase in response of the conifer root and butt rot pathogen (heterobasidion annosum) to osmotic and oxidative stress [corrected]. PloS one 20120101
Hydroxyl radical modification of collagen type II increases its arthritogenicity and immunogenicity. PloS one 20120101
Exploring mechanisms of diabetes-related macrovascular complications: role of methylglyoxal, a metabolite of glucose on regulation of vascular contractility. Journal of pharmacological sciences 20120101
Long term running biphasically improves methylglyoxal-related metabolism, redox homeostasis and neurotrophic support within adult mouse brain cortex. PloS one 20120101
Glycine therapy inhibits the progression of cataract in streptozotocin-induced diabetic rats. Molecular vision 20120101
Transcriptome analyses of a salt-tolerant cytokinin-deficient mutant reveal differential regulation of salt stress response by cytokinin deficiency. PloS one 20120101
Protein carbonylation and aggregation precede neuronal apoptosis induced by partial glutathione depletion. ASN neuro 20120101
17β-Estradiol is required for the sexually dimorphic effects of repeated binge-pattern alcohol exposure on the HPA axis during adolescence. PloS one 20120101
Macro-to-micro structural proteomics: native source proteins for high-throughput crystallization. PloS one 20120101
Optimization of time-course experiments for kinetic model discrimination. PloS one 20120101
Amyloid-β metabolite sensing: biochemical linking of glycation modification and misfolding. Journal of Alzheimer's disease : JAD 20120101
Glucose metabolite glyoxal induces senescence in telomerase-immortalized human mesenchymal stem cells. Chemistry Central journal 20120101
Inhibitory effects of methylglyoxal on light-induced stomatal opening and inward K+ channel activity in Arabidopsis. Bioscience, biotechnology, and biochemistry 20120101
Role of forkhead transcription factors in diabetes-induced oxidative stress. Experimental diabetes research 20120101
Comparative proteomic analysis of early salt stress-responsive proteins in roots of SnRK2 transgenic rice. Proteome science 20120101
Chemoinformatic identification of novel inhibitors against Mycobacterium tuberculosis L-aspartate α-decarboxylase. PloS one 20120101
L(+) and D(-) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of L(+) and D(-) lactate by reversed-phase liquid chromatography tandem mass spectrometry. Experimental diabetes research 20120101
Glyoxalase-I is a novel prognosis factor associated with gastric cancer progression. PloS one 20120101
The Complexity of Sporadic Alzheimer's Disease Pathogenesis: The Role of RAGE as Therapeutic Target to Promote Neuroprotection by Inhibiting Neurovascular Dysfunction. International journal of Alzheimer's disease 20120101
Major phenolic compounds, antioxidant capacity and antidiabetic potential of rice bean (Vigna umbellata L.) in China. International journal of molecular sciences 20120101
Hyperglycemia and endothelial dysfunction in atherosclerosis: lessons from type 1 diabetes. International journal of vascular medicine 20120101
Uptake and accumulation of oxidized low-density lipoprotein during Mycobacterium tuberculosis infection in guinea pigs. PloS one 20120101
Effect of dietary advanced glycation end products on mouse liver. PloS one 20120101
Glutathione homeostasis and functions: potential targets for medical interventions. Journal of amino acids 20120101
Honey's Ability to Counter Bacterial Infections Arises from Both Bactericidal Compounds and QS Inhibition. Frontiers in microbiology 20120101
Metabolomics analysis of Cistus monspeliensis leaf extract on energy metabolism activation in human intestinal cells. Journal of biomedicine & biotechnology 20120101
Destabilization of the outer and inner mitochondrial membranes by core and linker histones. PloS one 20120101
Paraoxonase 1 in chronic kidney failure. Journal of lipids 20120101
Oxygen radical-mediated oxidation reactions of an alanine peptide motif - density functional theory and transition state theory study. Chemistry Central journal 20120101
Transcriptional portrait of Actinobacillus pleuropneumoniae during acute disease--potential strategies for survival and persistence in the host. PloS one 20120101
Effects on post-prandial glucose and AGE precursors from two initial insulin strategies in patients with type 2 diabetes uncontrolled by oral agents. Journal of diabetes and its complications 20120101
Inflammation and the peritoneal membrane: causes and impact on structure and function during peritoneal dialysis. Mediators of inflammation 20120101
Serum levels of advanced glycation endproducts and other markers of protein damage in early diabetic nephropathy in type 1 diabetes. PloS one 20120101
Salmonella enterica: a surprisingly well-adapted intracellular lifestyle. Frontiers in microbiology 20120101
Glyoxal formation and its role in endogenous oxalate synthesis. Advances in urology 20120101
Comparative SILAC proteomic analysis of Trypanosoma brucei bloodstream and procyclic lifecycle stages. PloS one 20120101
Aldose reductase, oxidative stress, and diabetic mellitus. Frontiers in pharmacology 20120101
Methylglyoxal mediates adipocyte proliferation by increasing phosphorylation of Akt1. PloS one 20120101
Protective Effects of Corni Fructus against Advanced Glycation Endproducts and Radical Scavenging. Evidence-based complementary and alternative medicine : eCAM 20120101
Identification of functional differences in metabolic networks using comparative genomics and constraint-based models. PloS one 20120101
Role of operon aaoSo-mutT in antioxidant defense in Streptococcus oligofermentans. PloS one 20120101
Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats. Oxidative medicine and cellular longevity 20120101
Disrupted Signaling through the Fanconi Anemia Pathway Leads to Dysfunctional Hematopoietic Stem Cell Biology: Underlying Mechanisms and Potential Therapeutic Strategies. Anemia 20120101
Hyperglycemia increases muscle blood flow and alters endothelial function in adolescents with type 1 diabetes. Experimental diabetes research 20120101
Expression of transient receptor potential ankyrin 1 (TRPA1) and its role in insulin release from rat pancreatic beta cells. PloS one 20120101
Purification and properties of S-hydroxymethylglutathione dehydrogenase of Paecilomyces variotii no. 5, a formaldehyde-degrading fungus. AMB Express 20120101
Hydrogen-rich water inhibits glucose and α,β -dicarbonyl compound-induced reactive oxygen species production in the SHR.Cg-Leprcp/NDmcr rat kidney. Medical gas research 20120101
Pathological significance of mitochondrial glycation. International journal of cell biology 20120101
PanM, an acetyl-coenzyme A sensor required for maturation of L-aspartate decarboxylase (PanD). mBio 20120101
A novel source of methylglyoxal and glyoxal in retina: implications for age-related macular degeneration. PloS one 20120101
[The role of oxidative processes in augmentation of atherogenity of low density lipoprotein particles]. Kardiologiia 20120101
[The influence of glucose on the free radical peroxidation of low density lipoproteins in vitro and in vivo]. Biomeditsinskaia khimiia 20120101
Methylglyoxal activates the human transient receptor potential ankyrin 1 channel. The Journal of toxicological sciences 20120101
Aldolase B knockdown prevents high glucose-induced methylglyoxal overproduction and cellular dysfunction in endothelial cells. PloS one 20120101
Inhibitory effects of hydroxysafflor yellow A on the formation of advanced glycation end products in vitro. Biological & pharmaceutical bulletin 20120101
Methylglyoxal accumulation in arterial walls causes vascular contractile dysfunction in spontaneously hypertensive rats. Journal of pharmacological sciences 20120101
Inhibition of Advanced Glycation End-Product Formation by Origanum majorana L. In Vitro and in Streptozotocin-Induced Diabetic Rats. Evidence-based complementary and alternative medicine : eCAM 20120101
Cleavage of α-dicarbonyl compounds by terpene hydroperoxide. Bioscience, biotechnology, and biochemistry 20120101
Cytoplasmic and nuclear anti-apoptotic roles of αB-crystallin in retinal pigment epithelial cells. PloS one 20120101
Angiogenesis impairment in diabetes: role of methylglyoxal-induced receptor for advanced glycation endproducts, autophagy and vascular endothelial growth factor receptor 2. PloS one 20120101
[Nonspecific inflammation and structural changes in the arteries of hypertensive males at high and moderate risk for cardiovascular events]. Terapevticheskii arkhiv 20120101
Late-onset running biphasically improves redox balance, energy- and methylglyoxal-related status, as well as SIRT1 expression in mouse hippocampus. PloS one 20120101
Generation of singlet oxygen by the glyoxal-peroxynitrite system. Journal of the American Chemical Society 20111228
Multistep ultrahigh performance liquid chromatography/tandem mass spectrometry analysis for untargeted quantification of glycating activity and identification of most relevant glycation products. Analytical chemistry 20111215
Chemical modifications of peptides and their impact on food properties. Chemical reviews 20111214
Role of the glyoxalase system in astrocyte-mediated neuroprotection. The Journal of neuroscience : the official journal of the Society for Neuroscience 20111214
Selenium-induced up-regulation of the antioxidant defense and methylglyoxal detoxification system reduces salinity-induced damage in rapeseed seedlings. Biological trace element research 20111201
Selenium pretreatment upregulates the antioxidant defense and methylglyoxal detoxification system and confers enhanced tolerance to drought stress in rapeseed seedlings. Biological trace element research 20111201
Development and validation of a selective HPLC-ESI-MS/MS method for the quantification of glyoxal and methylglyoxal in atmospheric aerosols (PM2.5). Analytical and bioanalytical chemistry 20111201
Upregulation of aldolase B and overproduction of methylglyoxal in vascular tissues from rats with metabolic syndrome. Cardiovascular research 20111201
The in vitro glycation of human serum albumin in the presence of Zn(II). Journal of inorganic biochemistry 20111201
Protective measures against ultrafiltration failure in peritoneal dialysis patients. Clinics (Sao Paulo, Brazil) 20111201
Cross-linking mechanisms of arginine and lysine with α,β-dicarbonyl compounds in aqueous solution. The journal of physical chemistry. A 20111124
Moderate glycation of serum albumin affects folding, stability, and ligand binding. Clinica chimica acta; international journal of clinical chemistry 20111120
Structural variation in bacterial glyoxalase I enzymes: investigation of the metalloenzyme glyoxalase I from Clostridium acetobutylicum. The Journal of biological chemistry 20111104
Effect of micronutrients on methylglyoxal-mediated in vitro glycation of albumin. Biological trace element research 20111101
Determination of time-dependent accumulation of D-lactate in the streptozotocin-induced diabetic rat kidney by column-switching HPLC with fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111101
Comparison of glycation of glutathione S-transferase by methylglyoxal, glucose or fructose. Molecular and cellular biochemistry 20111101
Association of two glyoxalase I gene polymorphisms with nephropathy and retinopathy in Type 2 diabetes. Journal of endocrinological investigation 20111101
Transgenic potato overproducing L-ascorbic acid resisted an increase in methylglyoxal under salinity stress via maintaining higher reduced glutathione level and glyoxalase enzyme activity. Biotechnology letters 20111101
Differential effects of insulin on peripheral diabetes-related changes in mitochondrial bioenergetics: involvement of advanced glycosylated end products. Biochimica et biophysica acta 20111101
Role of age and uncoupling protein-2 in oxidative stress, RAGE/AGE interaction and inflammatory liver injury. Experimental gerontology 20111101
Methylglyoxal impairs insulin signalling and insulin action on glucose-induced insulin secretion in the pancreatic beta cell line INS-1E. Diabetologia 20111101
Manuka honey inhibits cell division in methicillin-resistant Staphylococcus aureus. The Journal of antimicrobial chemotherapy 20111101
Crh, the paralogue of the phosphocarrier protein HPr, controls the methylglyoxal bypass of glycolysis in Bacillus subtilis. Molecular microbiology 20111101
Retinal pericytes inhibit activated T cell proliferation. Investigative ophthalmology & visual science 20111101
Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals. Mechanisms of ageing and development 20111101
[The glucose, glycotoxins and glycation products: the involvement into pathogenesis of microangiopathies, arteriolosclerosis and atherosclerosis]. Klinicheskaia laboratornaia diagnostika 20111101
Sensitive determination of glyoxal, methylglyoxal and hydroxyacetaldehyde in environmental water samples by using dansylacetamidooxyamine derivatization and liquid chromatography/fluorescence. Analytica chimica acta 20111017
S-D-lactoylglutathione as a potential state marker for hemolysis. Medical hypotheses 20111001
pH stability of the stromelysin-1 catalytic domain and its mechanism of interaction with a glyoxal inhibitor. Biochimica et biophysica acta 20111001
Fibrin(ogen) may be an important target for methylglyoxal-derived AGE modification in elastic arteries of humans. Diabetes & vascular disease research 20111001
Advanced glycation urinary protein-bound biomarkers and severity of diabetic nephropathy in man. American journal of nephrology 20111001
A pilot study on the use of serum glyoxalase as a supplemental biomarker to predict malignant cases of the prostate in the PSA range of 4-20 ng/ml. The Indian journal of medical research 20111001
Methylglyoxal induces mitochondria-dependent apoptosis in sarcoma. Biochemistry. Biokhimiia 20111001
Survey of 1,2-dicarbonyl compounds in commercial honey of different floral origin. Journal of food science 20111001
Relationship of methylglyoxal-adduct biogenesis to LDL and triglyceride levels in diabetics. Life sciences 20110926
Quantitative infrared intensity studies of vapor-phase glyoxal, methylglyoxal, and 2,3-butanedione (diacetyl) with vibrational assignments. The journal of physical chemistry. A 20110908
Pyruvate kinase triggers a metabolic feedback loop that controls redox metabolism in respiring cells. Cell metabolism 20110907
Meal-induced increases in C-reactive protein, interleukin-6 and tumour necrosis factor α are attenuated by prandial + basal insulin in patients with Type 2 diabetes. Diabetic medicine : a journal of the British Diabetic Association 20110901
Methylglyoxal functions as Hill oxidant and stimulates the photoreduction of O(2) at photosystem I: a symptom of plant diabetes. Plant, cell & environment 20110901
Energy metabolism and ageing regulation: metabolically driven deamidation of triosephosphate isomerase may contribute to proteostatic dysfunction. Ageing research reviews 20110901
Quantification of the six major α-dicarbonyl contaminants in peritoneal dialysis fluids by UHPLC/DAD/MSMS. Analytical and bioanalytical chemistry 20110901
Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities. The Biochemical journal 20110901
Differential inhibition/inactivation of mitochondrial complex I implicates its alteration in malignant cells. Biochemistry. Biokhimiia 20110901
Amide bonds to the nitrogen atoms of cysteine and serine as 'weak points' in the backbones of proteins. Biochemistry 20110823
Laboratory investigation on the role of organics in atmospheric nanoparticle growth. The journal of physical chemistry. A 20110818
Dual effects of phloretin and phloridzin on the glycation induced by methylglyoxal in model systems. Chemical research in toxicology 20110815
Taste modulating N-(1-methyl-4-oxoimidazolidin-2-ylidene) α-amino acids formed from creatinine and reducing carbohydrates. Journal of agricultural and food chemistry 20110810
Glycation induction and antiglycation activity of skin care ingredients on living human skin explants. International journal of cosmetic science 20110801
Glyoxalase I polymorphism rs2736654 causing the Ala111Glu substitution modulates enzyme activity--implications for autism. Autism research : official journal of the International Society for Autism Research 20110801
Absolute configurations and stability of cyclic guanosine mono-adducts with glyoxal and methylglyoxal. Chirality 20110801
Myoglobin-H2O2 catalyzes the oxidation of β-ketoacids to α-dicarbonyls: mechanism and implications in ketosis. Free radical biology & medicine 20110801
Method for monitoring of the protein amino group changes during carbonylation. Clinical biochemistry 20110801
Hsp31 of Escherichia coli K-12 is glyoxalase III. Molecular microbiology 20110801
Cranberry phytochemicals inhibit glycation of human hemoglobin and serum albumin by scavenging reactive carbonyls. Food & function 20110801
Polyamines in aging and disease. Aging 20110801
Energy metabolism, proteotoxic stress and age-related dysfunction - protection by carnosine. Molecular aspects of medicine 20110801
Preferential recognition of methylglyoxal-modified calf thymus DNA by circulating antibodies in cancer patients. Indian journal of biochemistry & biophysics 20110801
A global perspective of the genetic basis for carbonyl stress resistance. G3 (Bethesda, Md.) 20110801
Novel lipophilic acetohydroxamic acid derivatives based on conformationally constrained spiro carbocyclic 2,6-diketopiperazine scaffolds with potent trypanocidal activity. Journal of medicinal chemistry 20110728
Diversity of plasmids encoding histidine decarboxylase gene in Tetragenococcus spp. isolated from Japanese fish sauce. International journal of food microbiology 20110715
Glucose autoxidation induces functional damage to proteins via modification of critical arginine residues. Biochemistry 20110712
Carbonyl oxides reactions from geraniol-trans-(3,7-dimethylocta-2,6-dien-1-ol), 6-methyl-5-hepten-2-one, and 6-hydroxy-4-methyl-4-hexenal ozonolysis: kinetics and mechanisms. The journal of physical chemistry. A 20110707
Pars plana vitrectomy for diabetic macular edema. Internal limiting membrane delamination vs posterior hyaloid removal. A prospective randomized trial. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20110701
The genetic architecture of branched-chain amino acid accumulation in tomato fruits. Journal of experimental botany 20110701
Heat-shock protein 27 (Hsp27) as a target of methylglyoxal in gastrointestinal cancer. Biochimica et biophysica acta 20110701
Functional and metabolic effects of adaptive glycerol kinase (GLPK) mutants in Escherichia coli. The Journal of biological chemistry 20110701
Evidence that carbonyl stress by methylglyoxal exposure induces DNA damage and spindle aberrations, affects mitochondrial integrity in mammalian oocytes and contributes to oocyte ageing. Human reproduction (Oxford, England) 20110701
Glycation of LDL by methylglyoxal increases arterial atherogenicity: a possible contributor to increased risk of cardiovascular disease in diabetes. Diabetes 20110701
Antioxidants halt axonal degeneration in a mouse model of X-adrenoleukodystrophy. Annals of neurology 20110701
Distinct synergistic action of piperacillin and methylglyoxal against Pseudomonas aeruginosa. Indian journal of experimental biology 20110701
In silico evidence for gluconeogenesis from fatty acids in humans. PLoS computational biology 20110701
New site(s) of methylglyoxal-modified human serum albumin, identified by multiple reaction monitoring, alter warfarin binding and prostaglandin metabolism. Chemico-biological interactions 20110630
Catalytic conversion of dihydroxyacetone to lactic acid using metal salts in water. ChemSusChem 20110620
1,4-Diamino-2-butanone, a wide-spectrum microbicide, yields reactive species by metal-catalyzed oxidation. Free radical biology & medicine 20110615
Mutations in PNKD causing paroxysmal dyskinesia alters protein cleavage and stability. Human molecular genetics 20110615
DNA damage induced by endogenous aldehydes: current state of knowledge. Mutation research 20110603
The proglycation effect of caffeic acid leads to the elevation of oxidative stress and inflammation in monocytes, macrophages and vascular endothelial cells. The Journal of nutritional biochemistry 20110601
Genome-wide analysis of rice and Arabidopsis identifies two glyoxalase genes that are highly expressed in abiotic stresses. Functional & integrative genomics 20110601
Metabolic engineering of 1,2-propanediol pathways in Corynebacterium glutamicum. Applied microbiology and biotechnology 20110601
Methylglyoxal and pulmonary hypertension in broiler chickens. Poultry science 20110601
Trait variation in yeast is defined by population history. PLoS genetics 20110601
Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract. Interdisciplinary toxicology 20110601
Developing resistance to aflatoxin in maize and cottonseed. Toxins 20110601
Differences in glyoxal and methylglyoxal metabolism determine cellular susceptibility to protein carbonylation and cytotoxicity. Chemico-biological interactions 20110530
Exogenous collagen crosslinking of the intervertebral disc restores joint stability after lumbar posterior decompression surgery. Spine 20110520
Ex vivo detection of histone H1 modified with advanced glycation end products. Free radical biology & medicine 20110515
Denuder sampling techniques for the determination of gas-phase carbonyl compounds: a comparison and characterisation of in situ and ex situ derivatisation methods. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110515
Differential effects of advanced glycation end-products on renal tubular cell inflammation. Nephrology (Carlton, Vic.) 20110501
Bacterial glyoxalase enzymes. Seminars in cell & developmental biology 20110501
The glyoxalase system of malaria parasites--implications for cell biology and general glyoxalase research. Seminars in cell & developmental biology 20110501
Glyoxalase system in yeasts: structure, function, and physiology. Seminars in cell & developmental biology 20110501
Methylglyoxal metabolism in trypanosomes and leishmania. Seminars in cell & developmental biology 20110501
Glyoxalase in tumourigenesis and multidrug resistance. Seminars in cell & developmental biology 20110501
Glyoxalase in ageing. Seminars in cell & developmental biology 20110501
Modification of Akt1 by methylglyoxal promotes the proliferation of vascular smooth muscle cells. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110501
Glyoxalase in diabetes, obesity and related disorders. Seminars in cell & developmental biology 20110501
An expeditious access to 5-pyrimidinol derivatives from cyclic methylglyoxal diadducts, formation of argpyrimidines under physiological conditions and discovery of new CFTR inhibitors. European journal of medicinal chemistry 20110501
Methylglyoxal-infused honey mimics the anti-Staphylococcus aureus biofilm activity of manuka honey: potential implication in chronic rhinosinusitis. The Laryngoscope 20110501
Identification of H₂O₂ as a major antimicrobial component in coffee. Food & function 20110501
Glycated AAV vectors: chemical redirection of viral tissue tropism. Bioconjugate chemistry 20110420
Genistein inhibits advanced glycation end product formation by trapping methylglyoxal. Chemical research in toxicology 20110418
Genotoxicity and immunogenicity of DNA-advanced glycation end products formed by methylglyoxal and lysine in presence of Cu2+. Biochemical and biophysical research communications 20110415
Polyvinylamine-graft-TEMPO adsorbs onto, oxidizes, and covalently bonds to wet cellulose. Biomacromolecules 20110411
Characteristic effects of methylglyoxal and its degraded product formate on viability of human histiocytes: a possible detoxification pathway of methylglyoxal. Biochemical and biophysical research communications 20110408
Reduced glutathione concentrations are not decreased in red blood cells of patients with long term type 1-diabetes. Scandinavian journal of clinical and laboratory investigation 20110401
Aspergillus nidulans transcription factor AtfA interacts with the MAPK SakA to regulate general stress responses, development and spore functions. Molecular microbiology 20110401
Protection from retinopathy and other complications in patients with type 1 diabetes of extreme duration: the joslin 50-year medalist study. Diabetes care 20110401
The question is, my dear watson, why did the dog not bark?: the joslin 50-year medalist study. Diabetes care 20110401
Efficiency of trapping methylglyoxal by phenols and phenolic acids. Journal of food science 20110401
[Arteriolosclerosis and atherosclerosis. Pathology of the distal and proximal arterial bed. Pathogenesis of diabetic microangiopathy]. Klinicheskaia laboratornaia diagnostika 20110401
Mutagenesis and repair induced by the DNA advanced glycation end product N2-1-(carboxyethyl)-2'-deoxyguanosine in human cells. Biochemistry 20110329
Effect of reactive oxygen and carbonyl species on crucial cellular antioxidant enzymes. Chemico-biological interactions 20110315
NADPH-dependent reductases involved in the detoxification of reactive carbonyls in plants. The Journal of biological chemistry 20110304
Increased plasma methylglyoxal level, inflammation, and vascular endothelial dysfunction in diabetic nephropathy. Clinical biochemistry 20110301
Delayed intervention with AGE inhibitors attenuates the progression of diabetes-accelerated atherosclerosis in diabetic apolipoprotein E knockout mice. Diabetologia 20110301
Overproduction of a rice aldo-keto reductase increases oxidative and heat stress tolerance by malondialdehyde and methylglyoxal detoxification. Plant molecular biology 20110301
Carbonylation contributes to SERCA2a activity loss and diastolic dysfunction in a rat model of type 1 diabetes. Diabetes 20110301
Chronic methylglyoxal infusion by minipump causes pancreatic beta-cell dysfunction and induces type 2 diabetes in Sprague-Dawley rats. Diabetes 20110301
Enhanced reactivity of Lys182 explains the limited efficacy of biogenic amines in preventing the inactivation of glucose-6-phosphate dehydrogenase by methylglyoxal. Bioorganic & medicinal chemistry 20110301
Cloning and characterization of a glyoxalase I gene from the osmotolerant yeast Candida magnoliae. Journal of microbiology and biotechnology 20110301
Chlorogenic acid inhibits the formation of advanced glycation end products and associated protein cross-linking. Archives of pharmacal research 20110301
A matter of life or death: modeling DNA damage and repair in bacteria. Biophysical journal 20110216
Alpha-synuclein deficiency leads to increased glyoxalase I expression and glycation stress. Cellular and molecular life sciences : CMLS 20110201
Medical-grade honey enriched with antimicrobial peptides has enhanced activity against antibiotic-resistant pathogens. European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20110201
Identification of glycolaldehyde as the key inhibitor of bioethanol fermentation by yeast and genome-wide analysis of its toxicity. Biotechnology letters 20110201
Networks of gene sharing among 329 proteobacterial genomes reveal differences in lateral gene transfer frequency at different phylogenetic depths. Molecular biology and evolution 20110201
Peritoneal clearance and transport of methylglyoxal. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20110201
Formation of nitrogen-containing oligomers by methylglyoxal and amines in simulated evaporating cloud droplets. Environmental science & technology 20110201
HdcB, a novel enzyme catalysing maturation of pyruvoyl-dependent histidine decarboxylase. Molecular microbiology 20110201
Closing the anion gap: contribution of D-lactate to diabetic ketoacidosis. Clinica chimica acta; international journal of clinical chemistry 20110130
Kinetics and mechanism of the glyoxal + HO2 reaction: conversion of HO2 to OH by carbonyls. The journal of physical chemistry. A 20110127
Formation of carcinogenic 4(5)-methylimidazole in Maillard reaction systems. Journal of agricultural and food chemistry 20110126
Overexpression of glyoxalase-I reduces hyperglycemia-induced levels of advanced glycation end products and oxidative stress in diabetic rats. The Journal of biological chemistry 20110114
Formation of arginine modifications in a model system of Nα-tert-butoxycarbonyl (Boc)-arginine with methylglyoxal. Journal of agricultural and food chemistry 20110112
Effects of ethyl pyruvate and other α-keto carboxylic acid derivatives in a rat model of multivisceral ischemia and reperfusion. The Journal of surgical research 20110101
Renal podocyte apoptosis in Zucker diabetic fatty rats: involvement of methylglyoxal-induced oxidative DNA damage. Journal of comparative pathology 20110101
Thermal analysis reveals differential effects of various crosslinkers on bovine annulus fibrosis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20110101
Optimization of protein crosslinking formulations for the treatment of degenerative disc disease. Spine 20110101
The influence of bicarbonate/lactate-buffered PD fluids on N{ε}-(carboxyethyl)lysine and N{ε}-(carboxymethyl)lysine in peritoneal effluent. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20110101
Monitoring nonenzymatic glycation of human immunoglobulin G by methylglyoxal and glyoxal: A spectroscopic study. Analytical biochemistry 20110101
YqhD: a broad-substrate range aldehyde reductase with various applications in production of biorenewable fuels and chemicals. Applied microbiology and biotechnology 20110101
Reactive metabolites and AGE/RAGE-mediated cellular dysfunction affect the aging process: a mini-review. Gerontology 20110101
Selection for low or high primary dormancy in Lolium rigidum Gaud seeds results in constitutive differences in stress protein expression and peroxidase activity. Journal of experimental botany 20110101
The DNA polymerase activity of Saccharomyces cerevisiae Rev1 is biologically significant. Genetics 20110101
Diabetic retinopathy: targeting vasoregression. Diabetes 20110101
Proximal tubule cell hypothesis for cardiorenal syndrome in diabetes. International journal of nephrology 20110101
A systems biology approach to investigate the effect of pH-induced gene regulation on solvent production by Clostridium acetobutylicum in continuous culture. BMC systems biology 20110101
The role of glyoxalases for sugar stress and aging, with relevance for dyskinesia, anxiety, dementia and Parkinson's disease. Aging 20110101
Proteomics analysis of methylglyoxal-induced neurotoxic effects in SH-SY5Y cells. Cell biochemistry and function 20110101
The glyoxalase system as an example of a cellular maintenance pathway with relevance to aging. Aging 20110101
Group II intron-anchored gene deletion in Clostridium. PloS one 20110101
Xenotransplantation of mitochondrial electron transfer enzyme, Ndi1, in myocardial reperfusion injury. PloS one 20110101
A synthetic library of RNA control modules for predictable tuning of gene expression in yeast. Molecular systems biology 20110101
Difluoromethylornithine is a novel inhibitor of Helicobacter pylori growth, CagA translocation, and interleukin-8 induction. PloS one 20110101
Characterization of proteome alterations in Phanerochaete chrysosporium in response to lead exposure. Proteome science 20110101
Two major medicinal honeys have different mechanisms of bactericidal activity. PloS one 20110101
Role of advanced glycation on aggregation and DNA binding properties of α-synuclein. Journal of Alzheimer's disease : JAD 20110101
Carotid intima-media thickness as a surrogate marker of cardiovascular disease in diabetes. Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
The antibacterial activity of honey derived from Australian flora. PloS one 20110101
Accumulation of renin and imidazolone in peritubular capillary endothelial cells in insulin-resistant hypertensive rats. Journal of nephrology 20110101
Evidence for reductive genome evolution and lateral acquisition of virulence functions in two Corynebacterium pseudotuberculosis strains. PloS one 20110101
Binge-pattern alcohol exposure during puberty induces long-term changes in HPA axis reactivity. PloS one 20110101
Photodynamic treatment induces an apoptotic pathway involving calcium, nitric oxide, p53, p21-activated kinase 2, and c-Jun N-terminal kinase and inactivates survival signal in human umbilical vein endothelial cells. International journal of molecular sciences 20110101
Postmyocardial infarct remodeling and heart failure: potential contributions from pro- and antiaging factors. Cardiology research and practice 20110101
Exploring metabolic pathway reconstruction and genome-wide expression profiling in Lactobacillus reuteri to define functional probiotic features. PloS one 20110101
Strain engineering for improved expression of recombinant proteins in bacteria. Microbial cell factories 20110101
Modification of collagen by 3-deoxyglucosone alters wound healing through differential regulation of p38 MAP kinase. PloS one 20110101
AGE-BSA down-regulates endothelial connexin43 gap junctions. BMC cell biology 20110101
An active site aromatic triad in Escherichia coli DNA Pol IV coordinates cell survival and mutagenesis in different DNA damaging agents. PloS one 20110101
The antioxidative effect of electro-acupuncture in a mouse model of Parkinson's disease. PloS one 20110101
Global analysis of gene expression in response to L-Cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica. BMC genomics 20110101
Sequencing and comparative genome analysis of two pathogenic Streptococcus gallolyticus subspecies: genome plasticity, adaptation and virulence. PloS one 20110101
Lipid peroxidation and total antioxidant capacity in vitreous, aqueous humor, and blood samples from patients with diabetic retinopathy. Molecular vision 20110101
The metabolic advantage of tumor cells. Molecular cancer 20110101
Chemical linkage to injected tissues is a distinctive property of oxidized avidin. PloS one 20110101
Global transcriptome response in Lactobacillus sakei during growth on ribose. BMC microbiology 20110101
Intuitive visualization and analysis of multi-omics data and application to Escherichia coli carbon metabolism. PloS one 20110101
Fisetin lowers methylglyoxal dependent protein glycation and limits the complications of diabetes. PloS one 20110101
Immortalized adult rodent Schwann cells as in vitro models to study diabetic neuropathy. Experimental diabetes research 20110101
Intermittent high glucose enhances apoptosis in INS-1 cells. Experimental diabetes research 20110101
Vascular homeostasis and angiogenesis determine therapeutic effectiveness in type 2 diabetes. International journal of vascular medicine 20110101
Control of genetically prescribed protein tyrosine kinase activities by environment-linked redox reactions. Enzyme research 20110101
Methylglyoxal-a potential risk factor of manuka honey in healing of diabetic ulcers. Evidence-based complementary and alternative medicine : eCAM 20110101
Synergistic use of plant-prokaryote comparative genomics for functional annotations. BMC genomics 20110101
Identification of host genes involved in geminivirus infection using a reverse genetics approach. PloS one 20110101
Insulin glycation by methylglyoxal results in native-like aggregation and inhibition of fibril formation. BMC biochemistry 20110101
Proteomic analysis reveals that iron availability alters the metabolic status of the pathogenic fungus Paracoccidioides brasiliensis. PloS one 20110101
Catabolic regulation analysis of Escherichia coli and its crp, mlc, mgsA, pgi and ptsG mutants. Microbial cell factories 20110101
Photo-products of retinal pigment epithelial bisretinoids react with cellular thiols. Molecular vision 20110101
Protein profiling of human nonpigmented ciliary epithelium cell secretome: the differentiation factors characterization for retinal ganglion cell line. Journal of biomedicine & biotechnology 20110101
NF-κB-inducing kinase increases renal tubule epithelial inflammation associated with diabetes. Experimental diabetes research 20110101
Polymicrobial Sepsis in an Immunocompetent Host due to Self Injection of Urine. Journal of global infectious diseases 20110101
Update on the management of diabetic polyneuropathies. Diabetes, metabolic syndrome and obesity : targets and therapy 20110101
Glucose and its metabolites have distinct effects on the calcium-induced mitochondrial permeability transition. Folia biologica 20110101
Topical application of L-arginine blocks advanced glycation by ascorbic acid in the lens of hSVCT2 transgenic mice. Molecular vision 20110101
Effect of exposure of human monocyte-derived macrophages to high, versus normal, glucose on subsequent lipid accumulation from glycated and acetylated low-density lipoproteins. Experimental diabetes research 20110101
Isoflurane's Effect on Protein Conformation as a Proposed Mechanism for Preconditioning. Biochemistry research international 20110101
Phenotype enhancement screen of a regulatory spx mutant unveils a role for the ytpQ gene in the control of iron homeostasis. PloS one 20110101
D-ribose induces cellular protein glycation and impairs mouse spatial cognition. PloS one 20110101
Tmem26 is dynamically expressed during palate and limb development but is not required for embryonic survival. PloS one 20110101
Horizontal and vertical growth of S. cerevisiae metabolic network. BMC evolutionary biology 20110101
Different impacts of cardiovascular risk factors on oxidative stress. International journal of molecular sciences 20110101
Cumulative number of cell divisions as a meaningful timescale for adaptive laboratory evolution of Escherichia coli. PloS one 20110101
Beyond genetic factors in familial amyloidotic polyneuropathy: protein glycation and the loss of fibrinogen's chaperone activity. PloS one 20110101
Biological potential of sixteen legumes in China. International journal of molecular sciences 20110101
DNA microarray analysis of the epithelial-mesenchymal transition of mesothelial cells in a rat model of peritoneal dialysis. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20110101
Dehydratase mediated 1-propanol production in metabolically engineered Escherichia coli. Microbial cell factories 20110101
CARD8 and NLRP1 undergo autoproteolytic processing through a ZU5-like domain. PloS one 20110101
Screening the MayBridge Rule of 3 Fragment Library for Compounds That Interact with the Trypanosoma brucei myo-Inositol-3-Phosphate Synthase and/or Show Trypanocidal Activity. Molecular biology international 20110101
Sulfurous gases as biological messengers and toxins: comparative genetics of their metabolism in model organisms. Journal of toxicology 20110101
Potential Therapeutic Roles for Inhibition of the PI3K/Akt/mTOR Pathway in the Pathophysiology of Diabetic Retinopathy. Journal of ophthalmology 20110101
Endoplasmic reticulum stress pathway-mediated apoptosis in macrophages contributes to the survival of Mycobacterium tuberculosis. PloS one 20110101
Increased renal methylglyoxal formation with down-regulation of PGC-1α-FBPase pathway in cystathionine γ-lyase knockout mice. PloS one 20110101
Modification of lipoprotein(a) by natural dicarbonyls induced their following free radical peroxidation. Doklady. Biochemistry and biophysics 20110101
Osmolarity and glucose differentially regulate aldose reductase activity in cultured mouse podocytes. Experimental diabetes research 20110101
Methylglyoxal: (active agent of manuka honey) in vitro activity against bacterial biofilms. International forum of allergy & rhinology 20110101
Protein modification by dicarbonyl molecular species in neurodegenerative diseases. Journal of amino acids 20110101
Defining the plant peroxisomal proteome: from Arabidopsis to rice. Frontiers in plant science 20110101
The anti-tumor effects of calorie restriction are correlated with reduced oxidative stress in ENU-induced gliomas. Pathobiology of aging & age related diseases 20110101
Bacterial metabolic 'toxins': a new mechanism for lactose and food intolerance, and irritable bowel syndrome. Toxicology 20101230
Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica. The Journal of biological chemistry 20101210
Methylglyoxal scavengers attenuate endothelial dysfunction induced by methylglyoxal and high concentrations of glucose. British journal of pharmacology 20101201
Eicosapentaenoic acid restores diabetic tubular injury through regulating oxidative stress and mitochondrial apoptosis. American journal of physiology. Renal physiology 20101201
Candesartan attenuates diabetic retinal vascular pathology by restoring glyoxalase-I function. Diabetes 20101201
The critical role of S-lactoylglutathione formation during methylglyoxal detoxification in Escherichia coli. Molecular microbiology 20101201
Ketonuria after fasting may be related to the metabolic superiority. Journal of Korean medical science 20101201
Compartmentation of redox metabolism in malaria parasites. PLoS pathogens 20101201
Modulation of the glyoxalase system in the aging model Podospora anserina: effects on growth and lifespan. Aging 20101201
Acid-base disorders in ICU patients. Electrolyte & blood pressure : E & BP 20101201
Dietary advanced glycation end products and aging. Nutrients 20101201
Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution. Journal of molecular biology 20101119
Properties and tissue distribution of a novel aldo-keto reductase encoding in a rat gene (Akr1b10). Archives of biochemistry and biophysics 20101115
Model representation of secondary organic aerosol in CMAQv4.7. Environmental science & technology 20101115
Acetyl radical production by the methylglyoxal-peroxynitrite system: a possible route for L-lysine acetylation. Chemical research in toxicology 20101115
2-DE based proteomic analysis of Saccharomyces cerevisiae wild and K+ transport-affected mutant (trk1,2) strains at the growth exponential and stationary phases. Journal of proteomics 20101110
Effect of methylglyoxal modification of human α-crystallin on the structure, stability and chaperone function. The protein journal 20101101
Relationship between Pentosidine and Pyridinoline Levels in Human Diabetic Cataract Lenses. Journal of clinical biochemistry and nutrition 20101101
Identification of a lipid peroxidation product as the source of oxidation-specific epitopes recognized by anti-DNA autoantibodies. The Journal of biological chemistry 20101029
Tenuigenin protects cultured hippocampal neurons against methylglyoxal-induced neurotoxicity. European journal of pharmacology 20101025
3-deoxygalactosone, a 'new' 1,2-dicarbonyl compound in milk products. Journal of agricultural and food chemistry 20101013
Cytotoxic role of methylglyoxal in rat retinal pericytes: Involvement of a nuclear factor-kappaB and inducible nitric oxide synthase pathway. Chemico-biological interactions 20101006
Influence of the microenvironment of thiol groups in low molecular mass thiols and serum albumin on the reaction with methylglyoxal. Chemico-biological interactions 20101006
Advanced glycation end products as biomarkers and gerontotoxins - A basis to explore methylglyoxal-lowering agents for Alzheimer's disease? Experimental gerontology 20101001
Subcellular distribution of glutathione and cysteine in cyanobacteria. Protoplasma 20101001
Carbonyl compounds methylglyoxal and glyoxal affect interleukin-8 secretion in intestinal cells by superoxide anion generation and activation of MAPK p38. Molecular nutrition & food research 20101001
Mitochondrial aldehyde dehydrogenase and cardiac diseases. Cardiovascular research 20101001
Maternally transmitted and food-derived glycotoxins: a factor preconditioning the young to diabetes? Diabetes care 20101001
Proteotoxicity and the contrasting effects of oxaloacetate and glycerol on Caenorhabditis elegans life span: a role for methylglyoxal? Rejuvenation research 20101001
Aldose reductase and AGE-RAGE pathways: central roles in the pathogenesis of vascular dysfunction in aging rats. Aging cell 20101001
Delphinidin, a dietary anthocyanidin in berry fruits, inhibits human glyoxalase I. Bioorganic & medicinal chemistry 20101001
Skin wound healing in diabetic β6 integrin-deficient mice. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20101001
Structure of LP2179, the first representative of Pfam family PF08866, suggests a new fold with a role in amino-acid metabolism. Acta crystallographica. Section F, Structural biology and crystallization communications 20101001
Genomic damage in endstage renal disease-contribution of uremic toxins. Toxins 20101001
Formation yields of glyoxal and methylglyoxal from the gas-phase OH radical-initiated reactions of toluene, xylenes, and trimethylbenzenes as a function of NO2 concentration. The journal of physical chemistry. A 20100923
Evidence of reactive aromatics as a major source of peroxy acetyl nitrate over China. Environmental science & technology 20100915
Redox homeostasis, antioxidant defense, and methylglyoxal detoxification as markers for salt tolerance in Pokkali rice. Protoplasma 20100901
A study of D-lactate and extracellular methylglyoxal production in lactate re-utilizing CHO cultures. Biotechnology and bioengineering 20100901
Anaerobic vs aerobic pathways of carbonyl and oxidant stress in human lens and skin during aging and in diabetes: A comparative analysis. Free radical biology & medicine 20100901
Methylglyoxal-induced imbalance in the ratio of vascular endothelial growth factor to angiopoietin 2 secreted by retinal pigment epithelial cells leads to endothelial dysfunction. Experimental physiology 20100901
Methylglyoxal is a predictor in type 2 diabetic patients of intima-media thickening and elevation of blood pressure. Hypertension (Dallas, Tex. : 1979) 20100901
In-cloud multiphase behaviour of acetone in the troposphere: gas uptake, Henry's law equilibrium and aqueous phase photooxidation. Chemosphere 20100901
Multi-parameter detection of diabetes mellitus on multichannel poly(dimethylsiloxane) analytical chips coupled with nanoband microelectrode arrays. Electrophoresis 20100901
Design, synthesis and biological evaluation of 3-(4-halophenyl)-3-oxopropanal and their derivatives as novel antibacterial agents. Chemical & pharmaceutical bulletin 20100901
Glyoxal-methylglyoxal cross-reactions in secondary organic aerosol formation. Environmental science & technology 20100815
Comparative proteomic analysis of early-stage soybean seedlings responses to flooding by using gel and gel-free techniques. Journal of proteome research 20100806
Transient inhibition of transforming growth factor-beta1 in human diabetic CD34+ cells enhances vascular reparative functions. Diabetes 20100801
Methylglyoxal increases cardiomyocyte ischemia-reperfusion injury via glycative inhibition of thioredoxin activity. American journal of physiology. Endocrinology and metabolism 20100801
Deletion of the receptor for advanced glycation end products reduces glomerulosclerosis and preserves renal function in the diabetic OVE26 mouse. Diabetes 20100801
Rapid profiling of a microbial genome using mixtures of barcoded oligonucleotides. Nature biotechnology 20100801
Methylglyoxal content in drinking coffee as a cytotoxic factor. Journal of food science 20100801
O-GlcNAc Modification: Friend or Foe in Diabetic Cardiovascular Disease. Korean diabetes journal 20100801
A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy. Nature communications 20100801
Interrelation between malonyl dialdehyde-dependent modification and cholesterol content in low-density lipoproteins. Bulletin of experimental biology and medicine 20100801
A novel capillary electrophoretic method for determining methylglyoxal and glyoxal in urine and water samples. Journal of chromatography. A 20100730
Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in a hypoxic environment. Cell death and differentiation 20100701
How honey kills bacteria. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100701
Infusion fluids contain harmful glucose degradation products. Intensive care medicine 20100701
Methylglyoxal-modified collagen promotes myofibroblast differentiation. Matrix biology : journal of the International Society for Matrix Biology 20100701
Characterization of the branched-chain amino acid aminotransferase enzyme family in tomato. Plant physiology 20100701
Glycobiology of the Leishmania parasite and emerging targets for antileishmanial drug discovery. Expert opinion on therapeutic targets 20100701
Fructose and cardiometabolic disorders: the controversy will, and must, continue. Clinics (Sao Paulo, Brazil) 20100701
The bHLH transcription factor POPEYE regulates response to iron deficiency in Arabidopsis roots. The Plant cell 20100701
Role of Lys-12 in catalysis by triosephosphate isomerase: a two-part substrate approach. Biochemistry 20100629
KIOM-79 prevents methyglyoxal-induced retinal pericyte apoptosis in vitro and in vivo. Journal of ethnopharmacology 20100616
Modifying apolipoprotein A-I by malondialdehyde, but not by an array of other reactive carbonyls, blocks cholesterol efflux by the ABCA1 pathway. The Journal of biological chemistry 20100611
Beneficial effects of cinnamon proanthocyanidins on the formation of specific advanced glycation endproducts and methylglyoxal-induced impairment on glucose consumption. Journal of agricultural and food chemistry 20100609
Methylglyoxal modulates immune responses: relevance to diabetes. Journal of cellular and molecular medicine 20100601
Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: possible links between diabetes and atherosclerosis. Biochimica et biophysica acta 20100601
Evaluation of dicarbonyls generated in a simulated indoor air environment using an in vitro exposure system. Toxicological sciences : an official journal of the Society of Toxicology 20100601
NAD(+) and metabolic regulation of age-related proteoxicity: A possible role for methylglyoxal? Experimental gerontology 20100601
Methylglyoxal-mediated anxiolysis involves increased protein modification and elevated expression of glyoxalase 1 in the brain. Journal of neurochemistry 20100601
Isoflurane's effect on interfacial dynamics in GAPDH influences methylglyoxal reactivity. Archives of biochemistry and biophysics 20100601
Neuropathy, retinopathy, and glucose-lowering treatments. Diabetes care 20100601
Possible links between intestinal permeability and food processing: A potential therapeutic niche for glutamine. Clinics (Sao Paulo, Brazil) 20100601
Interaction of methylglyoxal and hydrogen sulfide in rat vascular smooth muscle cells. Antioxidants & redox signaling 20100501
Methylglyoxal activates Gcn2 to phosphorylate eIF2alpha independently of the TOR pathway in Saccharomyces cerevisiae. Applied microbiology and biotechnology 20100501
Glycation of PDGF results in decreased biological activity. The international journal of biochemistry & cell biology 20100501
Hyperglycaemia-induced impairment of endothelium-dependent vasorelaxation in rat mesenteric arteries is mediated by intracellular methylglyoxal levels in a pathway dependent on oxidative stress. Diabetologia 20100501
Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of glyoxalase I from Leishmania infantum. Acta crystallographica. Section F, Structural biology and crystallization communications 20100501
Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria. The Plant cell 20100501
Cytoprotection by almond skin extracts or catechins of hepatocyte cytotoxicity induced by hydroperoxide (oxidative stress model) versus glyoxal or methylglyoxal (carbonylation model). Chemico-biological interactions 20100429
Molecular gastronomy: a new emerging scientific discipline. Chemical reviews 20100414
Lipid peroxidation in relation to ageing and the role of endogenous aldehydes in diabetes and other age-related diseases. Ageing research reviews 20100401
Fructose and moderately high dietary salt-induced hypertension: prevention by a combination of N-acetylcysteine and L-arginine. Molecular and cellular biochemistry 20100401
Modulation of advanced glycation endproduct synthesis by kynurenines in human lens proteins. Biochimica et biophysica acta 20100401
Increased glycation and oxidative damage to apolipoprotein B100 of LDL cholesterol in patients with type 2 diabetes and effect of metformin. Diabetes 20100401
Kinetic characterization and comparison of various protein crosslinking reagents for matrix modification. Journal of materials science. Materials in medicine 20100401
Hydroimidazolone modification of human alphaA-crystallin: Effect on the chaperone function and protein refolding ability. Biochimica et biophysica acta 20100401
GLO1 overexpression in human malignant melanoma. Melanoma research 20100401
Methylglyoxal has injurious effects on maturation of mouse oocytes, fertilization, and fetal development, via apoptosis. Toxicology letters 20100401
Protein modification and replicative senescence of WI-38 human embryonic fibroblasts. Aging cell 20100401
Nonenzymatic glycation impairs the antiinflammatory properties of apolipoprotein A-I. Arteriosclerosis, thrombosis, and vascular biology 20100401
Distinct subcellular localization in the cytosol and apicoplast, unexpected dimerization and inhibition of Plasmodium falciparum glyoxalases. Molecular microbiology 20100401
A matter of degrees: advancing our understanding of acrylamide. Environmental health perspectives 20100401
Identification of adducts formed in the reactions of malonaldehyde-glyoxal and malonaldehyde-methylglyoxal with adenosine and calf thymus DNA. Chemistry & biodiversity 20100401
Discovery and characterization of proteins associated with aflatoxin-resistance: evaluating their potential as breeding markers. Toxins 20100401
Calcineurin/Crz1 destabilizes Msn2 and Msn4 in the nucleus in response to Ca(2+) in Saccharomyces cerevisiae. The Biochemical journal 20100329
Analysis, distribution, and dietary exposure of glyoxal and methylglyoxal in cookies and their relationship with other heat-induced contaminants. Journal of agricultural and food chemistry 20100310
Mutagenic potential of DNA glycation: miscoding by (R)- and (S)-N2-(1-carboxyethyl)-2'-deoxyguanosine. Biochemistry 20100309
Effect of reactive-aldehydes on the modification and dysfunction of human serum albumin. Journal of pharmaceutical sciences 20100301
Two dicarbonyl compounds, 3-deoxyglucosone and methylglyoxal, differentially modulate dermal fibroblasts. Matrix biology : journal of the International Society for Matrix Biology 20100301
AGER1 regulates endothelial cell NADPH oxidase-dependent oxidant stress via PKC-delta: implications for vascular disease. American journal of physiology. Cell physiology 20100301
Rutin metabolites: novel inhibitors of nonoxidative advanced glycation end products. Free radical biology & medicine 20100301
Hyperglycemia impairs proteasome function by methylglyoxal. Diabetes 20100301
Binding of curcumin with glyoxalase I: Molecular docking, molecular dynamics simulations, and kinetics analysis. Biophysical chemistry 20100301
Comparative transcriptome analysis reveals novel roles of the Ras and cyclic AMP signaling pathways in environmental stress response and antifungal drug sensitivity in Cryptococcus neoformans. Eukaryotic cell 20100301
Inhibition of L-arginine metabolizing enzymes by L-arginine-derived advanced glycation end products. Journal of clinical biochemistry and nutrition 20100301
Oxidative stress and aging: is methylglyoxal the hidden enemy? Canadian journal of physiology and pharmacology 20100301
[Methylglyoxal--a test for impaired biological functions of exotrophy and endoecology, low glucose level in the cytosol and gluconeogenesis from fatty acids (a lecture)]. Klinicheskaia laboratornaia diagnostika 20100301
Different experimental approaches in modelling cataractogenesis: An overview of selenite-induced nuclear cataract in rats. Interdisciplinary toxicology 20100301
The anti-apoptotic function of human αA-crystallin is directly related to its chaperone activity. Cell death & disease 20100301
Microbial production and applications of 1,2-propanediol. Indian journal of microbiology 20100301
Anti-glycative effects of oleanolic acid and ursolic acid in kidney of diabetic mice. European journal of pharmacology 20100225
Stilbene glucoside from Polygonum multiflorum Thunb.: a novel natural inhibitor of advanced glycation end product formation by trapping of methylglyoxal. Journal of agricultural and food chemistry 20100224
Formation of pyrazines in Maillard model systems of lysine-containing dipeptides. Journal of agricultural and food chemistry 20100224
Effects of glyoxal or methylglyoxal on the metabolism of amino acids, lactate, glucose and acetate in the cerebral cortex of young and adult rats. Brain research 20100222
Molecular cloning and characterization of a novel glyoxalase I gene TaGly I in wheat (Triticum aestivum L.). Molecular biology reports 20100201
Thioflavin T fluorescence in human serum: correlations with vascular health and cardiovascular risk factors. Clinical biochemistry 20100201
Structural biology of S-adenosylmethionine decarboxylase. Amino acids 20100201
Incretin concepts. Diabetes care 20100201
Glycotoxines, carbonyl stress and relevance to diabetes and its complications. Physiological research 20100101
Hyperglycemic oxoaldehyde, glyoxal, causes barrier dysfunction, cytoskeletal alterations, and inhibition of angiogenesis in vascular endothelial cells: aminoguanidine protection. Molecular and cellular biochemistry 20100101
Hyperglycemia-induced reactive oxygen species increase expression of the receptor for advanced glycation end products (RAGE) and RAGE ligands. Diabetes 20100101
Methylglyoxal augments intracellular oxidative stress in human aortic endothelial cells. Free radical research 20100101
Impact of low glucose degradation product bicarbonate/lactate-buffered dialysis solution on the epithelial-mesenchymal transition of peritoneum. American journal of nephrology 20100101
Methylglyoxal induces cellular damage by increasing argpyrimidine accumulation and oxidative DNA damage in human lens epithelial cells. Biochemical and biophysical research communications 20100101
Alagebrium attenuates acute methylglyoxal-induced glucose intolerance in Sprague-Dawley rats. British journal of pharmacology 20100101
HIF-1alpha dysfunction in diabetes. Cell cycle (Georgetown, Tex.) 20100101
The path to next generation biofuels: successes and challenges in the era of synthetic biology. Microbial cell factories 20100101
The plastid isoform of triose phosphate isomerase is required for the postgerminative transition from heterotrophic to autotrophic growth in Arabidopsis. The Plant cell 20100101
Pyrosequencing of Mytilus galloprovincialis cDNAs: tissue-specific expression patterns. PloS one 20100101
Protein antioxidant response to the stress and the relationship between molecular structure and antioxidant function. PloS one 20100101
Methylglyoxal enhances sodium nitroprusside-induced relaxation in rat aorta. Journal of pharmacological sciences 20100101
The role of glyoxalase system in renal hypoxia. Advances in experimental medicine and biology 20100101
[Glycation of mitochondrial proteins, oxidative stress and aging]. Revista espanola de geriatria y gerontologia 20100101
Female reproductive dysfunction during ageing: role of methylglyoxal in the formation of advanced glycation endproducts in ovaries of reproductively-aged mice. Journal of biological regulators and homeostatic agents 20100101
Metabolic engineering of glyoxalase pathway for enhancing stress tolerance in plants. Methods in molecular biology (Clifton, N.J.) 20100101
Buthionine sulfoximine promotes methylglyoxal-induced apoptotic cell death and oxidative stress in endothelial cells. Biological & pharmaceutical bulletin 20100101
OptORF: Optimal metabolic and regulatory perturbations for metabolic engineering of microbial strains. BMC systems biology 20100101
Increased concentration of two different advanced glycation end-products detected by enzyme immunoassays with new monoclonal antibodies in sera of patients with rheumatoid arthritis. BMC musculoskeletal disorders 20100101
Peritoneal adipocytes and their role in inflammation during peritoneal dialysis. Mediators of inflammation 20100101
Troglitazone reduces glyoxalase I protein expression in glioma and potentiates the effects of chemotherapeutic agents. Journal of oncology 20100101
Posttranslational modification of human glyoxalase 1 indicates redox-dependent regulation. PloS one 20100101
Identification of the primary structure and post-translational modification of rat S-adenosylmethionine decarboxylase. Biological & pharmaceutical bulletin 20100101
Engineering cofactor preference of ketone reducing biocatalysts: A mutagenesis study on a γ-diketone reductase from the yeast Saccharomyces cerevisiae serving as an example. International journal of molecular sciences 20100101
Mitochondrial dysfunction, proteotoxicity, and aging: causes or effects, and the possible impact of NAD+-controlled protein glycation. Advances in clinical chemistry 20100101
Identification of latexin by a proteomic analysis in rat normal articular cartilage. Proteome science 20100101
Direct bacterial killing in vitro by recombinant Nod2 is compromised by Crohn's disease-associated mutations. PloS one 20100101
Genomes of three tomato pathogens within the Ralstonia solanacearum species complex reveal significant evolutionary divergence. BMC genomics 20100101
Aging, Proteotoxicity, Mitochondria, Glycation, NAD and Carnosine: Possible Inter-Relationships and Resolution of the Oxygen Paradox. Frontiers in aging neuroscience 20100101
Precursor of advanced glycation end products mediates ER-stress-induced caspase-3 activation of human dermal fibroblasts through NAD(P)H oxidase 4. PloS one 20100101
Effect of taurine supplementation on hyperhomocysteinemia and markers of oxidative stress in high fructose diet induced insulin resistance. Diabetology & metabolic syndrome 20100101
Endothelial dysfunction, inflammation, and apoptosis in diabetes mellitus. Mediators of inflammation 20100101
Involvement of TAGE-RAGE System in the Pathogenesis of Diabetic Retinopathy. Journal of ophthalmology 20100101
Inhibition of methylglyoxal-mediated protein modification in glyoxalase I overexpressing mouse lenses. Journal of ophthalmology 20100101
The glycobiome of the rumen bacterium Butyrivibrio proteoclasticus B316(T) highlights adaptation to a polysaccharide-rich environment. PloS one 20100101
Redox homeostasis of albumin in relation to alpha-lipoic acid and dihydrolipoic acid. Oxidative medicine and cellular longevity 20100101
Bench-to-bedside review: Glucose and stress conditions in the intensive care unit. Critical care (London, England) 20100101
Antiglycating potential of Zingiber officinalis and delay of diabetic cataract in rats. Molecular vision 20100101
An oligopeptide transporter of Mycobacterium tuberculosis regulates cytokine release and apoptosis of infected macrophages. PloS one 20100101
Comparison of the antimicrobial activity of Ulmo honey from Chile and Manuka honey against methicillin-resistant Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. BMC complementary and alternative medicine 20100101
Reconstruction and flux-balance analysis of the Plasmodium falciparum metabolic network. Molecular systems biology 20100101
The ubiquitous conserved glycopeptidase Gcp prevents accumulation of toxic glycated proteins. mBio 20100101
Chondroprotective effects and mechanisms of resveratrol in advanced glycation end products-stimulated chondrocytes. Arthritis research & therapy 20100101
The genome of Geobacter bemidjiensis, exemplar for the subsurface clade of Geobacter species that predominate in Fe(III)-reducing subsurface environments. BMC genomics 20100101
Methylglyoxal alters the function and stability of critical components of the protein quality control. PloS one 20100101
Elementary mode analysis for the rational design of efficient succinate conversion from glycerol by Escherichia coli. Journal of biomedicine & biotechnology 20100101
Architecture of y-family DNA polymerases relevant to translesion DNA synthesis as revealed in structural and molecular modeling studies. Journal of nucleic acids 20100101
Clostridium sticklandii, a specialist in amino acid degradation:revisiting its metabolism through its genome sequence. BMC genomics 20100101
The effects of methylglyoxal on glutathione S-transferase from Nicotiana tabacum. Bioscience, biotechnology, and biochemistry 20100101
Proline and glycinebetaine ameliorated NaCl stress via scavenging of hydrogen peroxide and methylglyoxal but not superoxide or nitric oxide in tobacco cultured cells. Bioscience, biotechnology, and biochemistry 20100101
Molecular mechanisms of persistence of mutualistic bacteria Photorhabdus in the entomopathogenic nematode host. PloS one 20100101
Diagnostic potential of plasma carboxymethyllysine and carboxyethyllysine in multiple sclerosis. Journal of neuroinflammation 20100101
Rat aldose reductase-like protein (AKR1B14) efficiently reduces the lipid peroxidation product 4-oxo-2-nonenal. Biological & pharmaceutical bulletin 20100101
New horizons in research on diabetic complications of the eye: special emphasis on diabetic cataracts and retinopathy. Journal of ophthalmology 20100101
Methylglyoxal augments angiotensin II-induced contraction in rat isolated carotid artery. Journal of pharmacological sciences 20100101
Apoplast proteome reveals that extracellular matrix contributes to multistress response in poplar. BMC genomics 20100101
The chaperone-dependent ubiquitin ligase CHIP targets HIF-1α for degradation in the presence of methylglyoxal. PloS one 20100101
TF-centered downstream gene set enrichment analysis: Inference of causal regulators by integrating TF-DNA interactions and protein post-translational modifications information. BMC bioinformatics 20100101
Experimental study of photooxidation products of ethylbenzene. Journal of environmental sciences (China) 20100101
Glycoxidative stress and cardiovascular complications in experimentally-induced diabetes: effects of antioxidant treatment. The open cardiovascular medicine journal 20100101
Modulation of the cellular expression of circulating advanced glycation end-product receptors in type 2 diabetic nephropathy. Experimental diabetes research 20100101
[Methylglyoxal--test for biological dysfunctions of homeostasis and endoecology, low cytosolic glucose level, and gluconeogenesis from fatty acids]. Terapevticheskii arkhiv 20100101
Ageing and its implications. Journal of oral and maxillofacial pathology : JOMFP 20100101
A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli. Advances and applications in bioinformatics and chemistry : AABC 20100101
Role of methylglyoxal in essential hypertension. The International journal of angiology : official publication of the International College of Angiology, Inc 20100101
Mechanism of lysine oxidation in human lens crystallins during aging and in diabetes. The Journal of biological chemistry 20091211
Glyoxalase I activity and immunoreactivity in the aging human lens. Biogerontology 20091201
Hyperglycemia and glycation in diabetic complications. Antioxidants & redox signaling 20091201
Food derived carbonyl compounds affect basal and stimulated secretion of interleukin-6 and -8 in Caco-2 cells. European journal of nutrition 20091201
'Blinding' of AMP-dependent kinase by methylglyoxal: a mechanism that allows perpetuation of hepatic insulin resistance? Medical hypotheses 20091201
Advanced glycation end products in extracellular matrix proteins contribute to the failure of sensory nerve regeneration in diabetes. Diabetes 20091201
Triosephosphate isomerase deficiency: new insights into an enigmatic disease. Biochimica et biophysica acta 20091201
Carbonated soft drinks and carbonyl stress burden. The Journal of toxicological sciences 20091201
Methylglyoxal causes dysfunction of thioredoxin and thioredoxin reductase in endothelial cells. Journal of pharmacological sciences 20091201
Generation of a rat monoclonal antibody specific for glyoxalase I. Hybridoma (2005) 20091201
Impaired gastric ulcer healing in diabetic mice: role of methylglyoxal. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20091201
Profiling of alpha-dicarbonyl content of commercial honeys from different botanical origins: identification of 3,4-dideoxyglucoson-3-ene (3,4-DGE) and related compounds. Journal of agricultural and food chemistry 20091125
Crystalline silica Min-U-Sil 5 induces oxidative stress in human bronchial epithelial cells BEAS-2B by reducing the efficiency of antiglycation and antioxidant enzymatic defenses. Chemico-biological interactions 20091110
Glycation of aspartate aminotransferase by methylglyoxal, effect of hydroxycitric and uric acid. Molecular and cellular biochemistry 20091101
Reductive metabolism of AGE precursors: a metabolic route for preventing AGE accumulation in cardiovascular tissue. Diabetes 20091101
C. elegans as model for the study of high glucose- mediated life span reduction. Diabetes 20091101
Antioxidant anti-inflammatory treatment in type 2 diabetes. Diabetes care 20091101
Shifting the disease management paradigm from glucose: what are the pros? Diabetes care 20091101
Effects of precursor concentration and acidic sulfate in aqueous glyoxal-OH radical oxidation and implications for secondary organic aerosol. Environmental science & technology 20091101
Secondary organic aerosol formation by self-reactions of methylglyoxal and glyoxal in evaporating droplets. Environmental science & technology 20091101
3-(6-Methyl-2-pyrid-yl)-2-phenyl-3,4-dihydro-1,3,2-benzoxaza-phosphinine 2-oxide. Acta crystallographica. Section E, Structure reports online 20091101
[Effects of N-acetylcysteine upon methylglyoxal-induced damage in hippocampal neuronal cells]. Zhonghua yi xue za zhi 20091027
Modification of collagen IV by glucose or methylglyoxal alters distinct mesangial cell functions. Journal of the American Society of Nephrology : JASN 20091001
Evidence for increased methylglyoxal in the vasculature of women with preeclampsia: role in upregulation of LOX-1 and arginase. Hypertension (Dallas, Tex. : 1979) 20091001
Critical evaluation of toxic versus beneficial effects of methylglyoxal. Biochemistry. Biokhimiia 20091001
Chemical and functional aspects of posttranslational modification of proteins. Acta naturae 20091001
Degradation of glucose: reinvestigation of reactive alpha-Dicarbonyl compounds. Journal of agricultural and food chemistry 20090923
Glucagon-like peptide-1 (GLP-1) protects against methylglyoxal-induced PC12 cell apoptosis through the PI3K/Akt/mTOR/GCLc/redox signaling pathway. Neuroscience 20090915
Two D-2-hydroxy-acid dehydrogenases in Arabidopsis thaliana with catalytic capacities to participate in the last reactions of the methylglyoxal and beta-oxidation pathways. The Journal of biological chemistry 20090911
Caffeic and chlorogenic acids in Ilex paraguariensis extracts are the main inhibitors of AGE generation by methylglyoxal in model proteins. Fitoterapia 20090901
Deletion of methylglyoxal synthase gene (mgsA) increased sugar co-metabolism in ethanol-producing Escherichia coli. Biotechnology letters 20090901
Hyperglycaemia impairs antithrombin secretion: possible contribution to the thrombotic risk of diabetes. Thrombosis research 20090901
Evaluation of the toxicity of stress-related aldehydes to photosynthesis in chloroplasts. Planta 20090901
Methylglyoxal: possible link between hyperglycaemia and immune suppression? Trends in endocrinology and metabolism: TEM 20090901
ATP regulates calcium efflux and growth in E. coli. Journal of molecular biology 20090807
Regio- and chemoselective multiple functionalization of chloropyrazine derivatives. Application to the synthesis of coelenterazine. Organic letters 20090806
Increased retinopathy occurrence in type 1 diabetes patients with increased serum levels of the advanced glycation endproduct hydroimidazolone. Acta ophthalmologica 20090801
Increased serum levels of methylglyoxal-derived hydroimidazolone-AGE are associated with increased cardiovascular disease mortality in nondiabetic women. Atherosclerosis 20090801
Development and validation of an HPLC method to quantify 3,4-dideoxyglucosone-3-ene in peritoneal dialysis fluids. Biomedical chromatography : BMC 20090801
Heat shock protein 27 modification is increased in the human diabetic failing heart. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090801
Oxyanion and tetrahedral intermediate stabilisation by subtilisin: detection of a new tetrahedral adduct. Biochimica et biophysica acta 20090801
Abstracts of the 2008 ISSOL Meeting. August 24-29, 2008. Florence, Italy. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20090801
Methylglyoxal contributes to the development of insulin resistance and salt sensitivity in Sprague-Dawley rats. Journal of hypertension 20090801
Cytotoxicity of Maillard reaction products determined with a peptide spot library. Molecular nutrition & food research 20090801
Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli. Nature chemical biology 20090801
Nephropathy and other topics. Diabetes care 20090801
Salt stress-induced alterations in the root proteome of barley genotypes with contrasting response towards salinity. Journal of experimental botany 20090801
Organocatalysis with endogenous compounds: towards novel non-enzymatic reactions. Bioorganic & medicinal chemistry letters 20090715
Nickel-based Enzyme Systems. The Journal of biological chemistry 20090710
A fluorescent probe for diacetyl detection. Journal of fluorescence 20090701
Enhanced methylglyoxal formation in the erythrocytes of hemodialyzed patients. Metabolism: clinical and experimental 20090701
Polymorphisms in glyoxalase 1 gene are not associated with vascular complications: the Hoorn and CoDAM studies. Journal of hypertension 20090701
EPHA2 is associated with age-related cortical cataract in mice and humans. PLoS genetics 20090701
Determination of carbonyl compounds in beer by derivatisation and headspace solid-phase microextraction in combination with gas chromatography and mass spectrometry. Journal of chromatography. A 20090626
Thermodynamics and kinetics of methylglyoxal dimer formation: a computational study. The journal of physical chemistry. A 20090625
KTN (RCK) domains regulate K+ channels and transporters by controlling the dimer-hinge conformation. Structure (London, England : 1993) 20090610
Methylglyoxal induced activation of murine peritoneal macrophages and surface markers of T lymphocytes in sarcoma-180 bearing mice: involvement of MAP kinase, NF-kappa beta signal transduction pathway. Molecular immunology 20090601
Methylglyoxal-induced mitochondrial dysfunction in vascular smooth muscle cells. Biochemical pharmacology 20090601
Characterization and the possible formation mechanism of 2-acetyl-1-pyrroline in aromatic vegetable soybean (Glycine max L.). Journal of food science 20090601
The origin of methylglyoxal in New Zealand manuka (Leptospermum scoparium) honey. Carbohydrate research 20090526
Yields of carbonyl products from gas-phase reactions of fragrance compounds with OH radical and ozone. Environmental science & technology 20090515
Plasma advanced glycation endproduct, methylglyoxal-derived hydroimidazolone is elevated in young, complication-free patients with Type 1 diabetes. Clinical biochemistry 20090501
Specific local cardiovascular changes of Nepsilon-(carboxymethyl)lysine, vascular endothelial growth factor, and Smad2 in the developing embryos coincide with maternal diabetes-induced congenital heart defects. Diabetes 20090501
Phosphorylation on Thr-106 and NO-modification of glyoxalase I suppress the TNF-induced transcriptional activity of NF-kappaB. Molecular and cellular biochemistry 20090501
Amyloid-dependent triosephosphate isomerase nitrotyrosination induces glycation and tau fibrillation. Brain : a journal of neurology 20090501
Formation of styrene during the Maillard reaction is negligible. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090501
Methylglyoxal, protein binding and biological samples: are we getting the true measure? Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090415
Dicarbonyl-induced accelerated aging in vitro in human skin fibroblasts. Biogerontology 20090401
Inhibition of human muscle-specific enolase by methylglyoxal and irreversible formation of advanced glycation end products. Journal of enzyme inhibition and medicinal chemistry 20090401
Collagen cross-links reduce corneal permeability. Investigative ophthalmology & visual science 20090401
Glyoxalase I overexpression ameliorates renal ischemia-reperfusion injury in rats. American journal of physiology. Renal physiology 20090401
7-O-galloyl-D-sedoheptulose is a novel therapeutic agent against oxidative stress and advanced glycation endproducts in the diabetic kidney. Biological & pharmaceutical bulletin 20090401
Superoxide formation as a result of interaction of L-lysine with dicarbonyl compounds and its possible mechanism. Biochemistry. Biokhimiia 20090401
Impact of methylglyoxal and high glucose co-treatment on human mononuclear cells. International journal of molecular sciences 20090401
Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress. Chemico-biological interactions 20090316
Fructose and carbonyl metabolites as endogenous toxins. Chemico-biological interactions 20090316
Cytoprotective mechanisms of carbonyl scavenging drugs in isolated rat hepatocytes. Chemico-biological interactions 20090316
N-Terminal 2,3-diaminopropionic acid (Dap) peptides as efficient methylglyoxal scavengers to inhibit advanced glycation endproduct (AGE) formation. Bioorganic & medicinal chemistry 20090315
Effect of relative humidity on gas/particle partitioning and aerosol mass yield in the photooxidation of p-xylene. Environmental science & technology 20090315
New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues of S-adenosylmethionine. Journal of medicinal chemistry 20090312
Ultra performance liquid chromatography-mass spectrometric determination of the site specificity of modification of beta-casein by glucose and methylglyoxal. Amino acids 20090301
The modification of alpha-synuclein by dicarbonyl compounds inhibits its fibril-forming process. Biochimica et biophysica acta 20090301
Ratio of the vitreous vascular endothelial growth factor and pigment epithelial-derived factor in Eales disease. Journal of ocular biology, diseases, and informatics 20090301
Methylglyoxal induces peritoneal thickening by mesenchymal-like mesothelial cells in rats. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090201
High-performance liquid chromatographic determination of creatine kinase activity influenced by methylglyoxal. Biomedical chromatography : BMC 20090201
The influence of disinfection on aquatic biodegradable organic carbon formation. Water research 20090201
Role of cysteine residues in the enhancement of chaperone function in methylglyoxal-modified human alpha A-crystallin. Molecular and cellular biochemistry 20090201
Reaction mechanism of the binuclear zinc enzyme glyoxalase II - A theoretical study. Journal of inorganic biochemistry 20090201
Phosphatidylserine decarboxylases, key enzymes of lipid metabolism. IUBMB life 20090201
Genome-wide responses to carbonyl electrophiles in Bacillus subtilis: control of the thiol-dependent formaldehyde dehydrogenase AdhA and cysteine proteinase YraA by the MerR-family regulator YraB (AdhR). Molecular microbiology 20090201
Methylglyoxal inhibits smooth muscle contraction in isolated blood vessels. Journal of pharmacological sciences 20090201
Dicarbonyl products of the OH radical-initiated reaction of a series of aromatic hydrocarbons. Environmental science & technology 20090201
A glutathione-specific aldose reductase of Leishmania donovani and its potential implications for methylglyoxal detoxification pathway. Gene 20090115
The formation of argpyrimidine, a methylglyoxal-arginine adduct, in the nucleus of neural cells. Biochemical and biophysical research communications 20090109
Primary atmospheric oxidation mechanism for toluene. The journal of physical chemistry. A 20090108
Exogenous collagen cross-linking reduces scleral permeability: modeling the effects of age-related cross-link accumulation. Investigative ophthalmology & visual science 20090101
A fluorometric high-performance liquid chromatography procedure for simultaneous determination of methylamine and aminoacetone in blood and tissues. Analytical biochemistry 20090101
Glyoxalase II does not support methylglyoxal detoxification but serves as a general trypanothione thioesterase in African trypanosomes. Molecular and biochemical parasitology 20090101
A novel mechanism of methylglyoxal cytotoxicity in neuroglial cells. Journal of neurochemistry 20090101
A comparative study of methylglyoxal metabolism in trypanosomatids. The FEBS journal 20090101
[methylglyoxal-induced superoxide anion production in endothelial cells]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20090101
Autothermal catalytic partial oxidation of glycerol to syngas and to non-equilibrium products. ChemSusChem 20090101
Alteration of renal respiratory Complex-III during experimental type-1 diabetes. BMC endocrine disorders 20090101
N(epsilon)-(Carboxymethyl)lysine and Coronary Atherosclerosis-Associated Low Density Lipoprotein Abnormalities in Type 2 Diabetes: Current Status. Journal of clinical biochemistry and nutrition 20090101
Deamidation alters interactions of beta-crystallins in hetero-oligomers. Molecular vision 20090101
Effect of glucose degradation products, glucose-containing dialysate and icodextrin on AQP1 and eNOS expression in cultured endothelial cells. Journal of nephrology 20090101
A common and unstable copy number variant is associated with differences in Glo1 expression and anxiety-like behavior. PloS one 20090101
Biological effects of electrolyzed water in hemodialysis. Nephron. Clinical practice 20090101
CYP17, GSTP1, PON1 and GLO1 gene polymorphisms as risk factors for breast cancer: an Italian case-control study. BMC cancer 20090101
Postprandial hyperglycemia as an etiological factor in vascular failure. Cardiovascular diabetology 20090101
Azathioprine favourably influences the course of malaria. Malaria journal 20090101
NAD+ availability and proteotoxicity. Neuromolecular medicine 20090101
Carnosine and its possible roles in nutrition and health. Advances in food and nutrition research 20090101
Independent inactivation of arginine decarboxylase genes by nonsense and missense mutations led to pseudogene formation in Chlamydia trachomatis serovar L2 and D strains. BMC evolutionary biology 20090101
Association between carotid diameter and the advanced glycation end product N-epsilon-carboxymethyllysine (CML). Cardiovascular diabetology 20090101
Advanced glycation of the Arg-Gly-Asp (RGD) tripeptide motif modulates retinal microvascular endothelial cell dysfunction. Molecular vision 20090101
Genome-wide screen of genes required for caffeine tolerance in fission yeast. PloS one 20090101
Glyoxalase I gene deletion mutants of Leishmania donovani exhibit reduced methylglyoxal detoxification. PloS one 20090101
Sugar metabolism, redox balance and oxidative stress response in the respiratory yeast Kluyveromyces lactis. Microbial cell factories 20090101
The antibacterial properties of Malaysian tualang honey against wound and enteric microorganisms in comparison to manuka honey. BMC complementary and alternative medicine 20090101
The pathogenic properties of a novel and conserved gene product, KerV, in proteobacteria. PloS one 20090101
Inherited glutathione reductase deficiency and Plasmodium falciparum malaria--a case study. PloS one 20090101
[Progress in fundamental research: perspectives of cardiology]. Terapevticheskii arkhiv 20090101
Cellulosic hydrolysate toxicity and tolerance mechanisms in Escherichia coli. Biotechnology for biofuels 20090101
Urea transport across peritoneal membrane in vitro: influence of protamine sulfate, glyoxal, and methylglyoxal. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20090101
Initial activation of EpCAM cleavage via cell-to-cell contact. BMC cancer 20090101
OXavidin for tissue targeting biotinylated therapeutics. Journal of biomedicine & biotechnology 20090101
Methylglyoxal-derivative advanced glycation endproducts: detection by competitive immunofluorometric assay and quantifying in serum and urine. Clinical laboratory 20090101
Determination of oxidative stress markers and their importance in early diagnosis of uremia-related complications. Indian journal of nephrology 20090101
Oxidative stress and anxiety: relationship and cellular pathways. Oxidative medicine and cellular longevity 20090101
Thermochemistry and kinetics of acetonylperoxy radical isomerisation and decomposition: a quantum chemistry and CVT/SCT approach. Physical chemistry chemical physics : PCCP 20081221
Structural basis for putrescine activation of human S-adenosylmethionine decarboxylase. Biochemistry 20081216
Protein glycation in vivo: functional and structural effects on yeast enolase. The Biochemical journal 20081215
Leptin decreases postprandially in people with type 2 diabetes, an effect reduced by the cooking method. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20081201
Methylglyoxal mediates vascular inflammation via JNK and p38 in human endothelial cells. American journal of physiology. Cell physiology 20081201
Degradation of tert-butyl formate and its intermediates by an ozone/UV process. Chemosphere 20081201
Methylglyoxal accumulation by glutathione depletion leads to cell cycle arrest in Dictyostelium. Molecular microbiology 20081201
Alteration in glycerol and metalloid permeability by a single mutation in the extracellular C-loop of Leishmania major aquaglyceroporin LmAQP1. Molecular microbiology 20081201
The repertoire and dynamics of evolutionary adaptations to controlled nutrient-limited environments in yeast. PLoS genetics 20081201
Sensitivity modeling study for an ozone occurrence during the 1996 Paso Del Norte Ozone Campaign. International journal of environmental research and public health 20081201
4-Acetyl-3,3-diethyl-5-hydr-oxy-2-morpholino-2,3-dihydro-1-benzofuran. Acta crystallographica. Section E, Structure reports online 20081201
Role of Gcn4 for adaptation to methylglyoxal in Saccharomyces cerevisiae: methylglyoxal attenuates protein synthesis through phosphorylation of eIF2alpha. Biochemical and biophysical research communications 20081128
Modulation of methylglyoxal and glutathione by soybean isoflavones in mild streptozotocin-induced diabetic rats. Nutrition, metabolism, and cardiovascular diseases : NMCD 20081101
Activation of macrophages and lymphocytes by methylglyoxal against tumor cells in the host. International immunopharmacology 20081101
Lymphocytes of type 2 diabetic women carry a high load of stable chromosomal aberrations: a novel risk factor for disease-related early death. Diabetes 20081101
Inhibitory effect of vanillic acid on methylglyoxal-mediated glycation in apoptotic Neuro-2A cells. Neurotoxicology 20081101
In vitro nonenzymatic glycation of guanosine 5'-triphosphate by dihydroxyacetone phosphate. Analytical and bioanalytical chemistry 20081101
Advanced glycation end products of DNA: quantification of N2-(1-Carboxyethyl)-2'-deoxyguanosine in biological samples by liquid chromatography electrospray ionization tandem mass spectrometry. Chemical research in toxicology 20081101
Cytotoxicity of advanced glycation endproducts in human micro- and astroglial cell lines depends on the degree of protein glycation. Journal of neural transmission (Vienna, Austria : 1996) 20081101
Advanced glycation of type I collagen and fibronectin modifies periodontal cell behavior. Journal of periodontology 20081101
Diagnosis of soil-transmitted helminths in the era of preventive chemotherapy: effect of multiple stool sampling and use of different diagnostic techniques. PLoS neglected tropical diseases 20081101
Glyoxalase pathway of trypanosomatid parasites: a promising chemotherapeutic target. Current drug targets 20081101
Atmospheric chemistry of acetylacetone. Environmental science & technology 20081101
Enhanced production of 1,2-propanediol by tpi1 deletion in Saccharomyces cerevisiae. Journal of microbiology and biotechnology 20081101
Polymorphonuclear leukocyte injury by methylglyoxal and hydrogen peroxide: a possible pathological role for enhanced oxidative stress in chronic kidney disease. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001
RAGE expression in the human peritoneal membrane. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20081001
Activation of NF-E2-related factor-2 reverses biochemical dysfunction of endothelial cells induced by hyperglycemia linked to vascular disease. Diabetes 20081001
Surface chemistry reactions of alpha-terpineol [(R)-2-(4-methyl-3-cyclohexenyl)isopropanol] with ozone and air on a glass and a vinyl tile. Indoor air 20081001
Erythrocyte programmed cell death. IUBMB life 20081001
Apple polyphenols, phloretin and phloridzin: new trapping agents of reactive dicarbonyl species. Chemical research in toxicology 20081001
Expression of Xhdsi-1VOC, a novel member of the vicinal oxygen chelate (VOC) metalloenzyme superfamily, is up-regulated in leaves and roots during desiccation in the resurrection plant Xerophyta humilis (Bak) Dur and Schinz. Journal of experimental botany 20081001
Dicarbonyls linked to damage in the powerhouse: glycation of mitochondrial proteins and oxidative stress. Biochemical Society transactions 20081001
Protein glycation inhibitors from the fruiting body of Phellinus linteus. Biological & pharmaceutical bulletin 20081001
[Methylglyoxal-induced apoptosis of endothelial cells]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20081001
Is the anti-hypertensive effect of dietary supplements via aldehydes reduction evidence based? A systematic review. Clinical and experimental hypertension (New York, N.Y. : 1993) 20081001
International Diabetes Federation guideline for management of postmeal glucose: a review of recommendations. Diabetic medicine : a journal of the British Diabetic Association 20081001
3-Eth-oxy-4-hydroxy-benzaldehyde. Acta crystallographica. Section E, Structure reports online 20081001
Antioxidant properties of argpyrimidine. European journal of pharmacology 20080928
Crenarchaeal arginine decarboxylase evolved from an S-adenosylmethionine decarboxylase enzyme. The Journal of biological chemistry 20080919
Capillary gas chromatographic determination of methylglyoxal from serum of diabetic patients by precolumn derivatization with 1,2-diamonopropane. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080915
A novel derivatization approach for simultaneous determination of glyoxal, methylglyoxal, and 3-deoxyglucosone in plasma by gas chromatography-mass spectrometry. Journal of chromatography. A 20080912
Pericyte migration: a novel mechanism of pericyte loss in experimental diabetic retinopathy. Diabetes 20080901
Ethyl pyruvate and ethyl lactate down-regulate the production of pro-inflammatory cytokines and modulate expression of immune receptors. Biochemical pharmacology 20080901
Methylglyoxal production in vascular smooth muscle cells from different metabolic precursors. Metabolism: clinical and experimental 20080901
Aminoacetone, a putative endogenous source of methylglyoxal, causes oxidative stress and death to insulin-producing RINm5f cells. Chemical research in toxicology 20080901
Modulation of insulin action by advanced glycation endproducts: a new player in the field. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20080901
Formation of 2,5-dimethyl-4-hydroxy-3(2H)-furanone through methylglyoxal: a Maillard reaction intermediate. Journal of agricultural and food chemistry 20080827
Biosynthetic mechanism of 2-acetyl-1-pyrroline and its relationship with Delta1-pyrroline-5-carboxylic acid and methylglyoxal in aromatic rice (Oryza sativa L.) callus. Journal of agricultural and food chemistry 20080827
Telmisartan inhibits methylglyoxal-mediated cell death in human vascular endothelium. Biochemical and biophysical research communications 20080822
Analysis of a 30 kbp plasmid encoding histidine decarboxylase gene in Tetragenococcus halophilus isolated from fish sauce. International journal of food microbiology 20080815
Reagentless amperometric formaldehyde-selective biosensors based on the recombinant yeast formaldehyde dehydrogenase. Talanta 20080815
A practical alternative to chemiluminescence-based detection of nitrogen dioxide: cavity attenuated phase shift spectroscopy. Environmental science & technology 20080815
Identification and monitoring of intermediates and products in the acrylamide pathway using online analysis. Journal of agricultural and food chemistry 20080813
Cytoprotective effects of phenolic acids on methylglyoxal-induced apoptosis in Neuro-2A cells. Molecular nutrition & food research 20080801
A novel nutraceutical property of select sorghum (Sorghum bicolor) brans: inhibition of protein glycation. Phytotherapy research : PTR 20080801
Use of capillary electrophoresis to evaluate protective effects of methylglyoxal scavengers on the activity of creatine kinase. Journal of separation science 20080801
Genetic and Molecular Basis of QTL of Diabetes in Mouse: Genes and Polymorphisms. Current genomics 20080801
Mechanism of the quorum-quenching lactonase (AiiA) from Bacillus thuringiensis. 1. Product-bound structures. Biochemistry 20080722
Chemical modulation of the chaperone function of human alphaA-crystallin. Journal of biochemistry 20080701
Laboratory evolution of Pyrococcus furiosus alcohol dehydrogenase to improve the production of (2S,5S)-hexanediol at moderate temperatures. Extremophiles : life under extreme conditions 20080701
Capillary gas chromatographic determination of methylglyoxal from serum of diabetic patients by precolumn derivatization using meso-stilbenediamine as derivatizing reagent. Journal of chromatographic science 20080701
Feasibility of detection and quantification of gas-phase carbonyls in indoor environments using PFBHA derivatization and solid-phase microextraction (SPME). Journal of environmental monitoring : JEM 20080701
Dietary soy isoflavones increase insulin secretion and prevent the development of diabetic cataracts in streptozotocin-induced diabetic rats. Nutrition research (New York, N.Y.) 20080701
Reduced expression of glyoxalase-1 mRNA in mood disorder patients. Neuroscience letters 20080620
Advanced glycation end-products (AGEs): involvement in aging and in neurodegenerative diseases. Amino acids 20080601
Binding of lipoic acid induces conformational change and appearance of a new binding site in methylglyoxal modified serum albumin. The protein journal 20080601
Effects of cross-link breakers, glycation inhibitors and insulin sensitisers on HDL function and the non-enzymatic glycation of apolipoprotein A-I. Diabetologia 20080601
Identification and characterization of a plastid-localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification. Journal of experimental botany 20080601
Formate excretion in urine of rats fed dimethylaminoazobenzene-rich diets: the possibility of formate formation from D-lactate. Acta medica Okayama 20080601
Neurodegenerative diseases of the retina and potential for protection and recovery. Current neuropharmacology 20080601
Proline and glycinebetaine enhance antioxidant defense and methylglyoxal detoxification systems and reduce NaCl-induced damage in cultured tobacco cells. Journal of plant physiology 20080526
Endothelial dysfunction in patients with chronic kidney disease results from advanced glycation end products (AGE)-mediated inhibition of endothelial nitric oxide synthase through RAGE activation. Clinical journal of the American Society of Nephrology : CJASN 20080501
Alpha-aminoazaheterocyclic-methylglyoxal adducts do not inhibit cystic fibrosis transmembrane conductance regulator chloride channel activity. The Journal of pharmacology and experimental therapeutics 20080501
Methylglyoxal increase in uremia with special reference to snakebite-mediated acute renal failure. Clinica chimica acta; international journal of clinical chemistry 20080501
Renal toxicity mediated by glucose degradation products in a rat model of advanced renal failure. European journal of clinical investigation 20080501
Bis(guanylhydrazones) negatively affect in vitro germination of kiwifruit pollen and alter the endogenous polyamine pool. Plant biology (Stuttgart, Germany) 20080501
Structure of isochorismate synthase in complex with magnesium. Acta crystallographica. Section D, Biological crystallography 20080501
The anticonvulsant activity of acetone does not depend upon its metabolites. Epilepsia 20080501
Caffeine induces cell death via activation of apoptotic signal and inactivation of survival signal in human osteoblasts. International journal of molecular sciences 20080501
Biochemical origins of lactaldehyde and hydroxyacetone in Methanocaldococcus jannaschii. Biochemistry 20080429
Decreasing intracellular superoxide corrects defective ischemia-induced new vessel formation in diabetic mice. The Journal of biological chemistry 20080418
The role of methylglyoxal in the non-enzymatic conversion of tryptophan, its methyl ester and tryptamine to 1-acetyl-beta-carbolines. Bioorganic & medicinal chemistry 20080415
Thermal stability of carbonyl radicals. Part II. Reactions of methylglyoxyl and methylglyoxylperoxy radicals at 1 bar in the temperature range 275-311 K. Physical chemistry chemical physics : PCCP 20080407
Enhancing salt tolerance in a crop plant by overexpression of glyoxalase II. Transgenic research 20080401
Methylglyoxal and methylglyoxal-arginine adducts do not directly inhibit endothelial nitric oxide synthase. Annals of the New York Academy of Sciences 20080401
Suppression of renal alpha-dicarbonyl compounds generated following ureteral obstruction by kidney-specific alpha-dicarbonyl/L-xylulose reductase. Annals of the New York Academy of Sciences 20080401
Usefulness of antibodies for evaluating the biological significance of AGEs. Annals of the New York Academy of Sciences 20080401
Growth of Bradyrhizobium sp. SEMIA 6144 in response to methylglyoxal: role of glutathione. Current microbiology 20080401
Extracellular methylglyoxal toxicity in Saccharomyces cerevisiae: role of glucose and phosphate ions. Journal of applied microbiology 20080401
Identification and quantification of methylglyoxal as the dominant antibacterial constituent of Manuka (Leptospermum scoparium) honeys from New Zealand. Molecular nutrition & food research 20080401
Structure-activity relationship of human GLO I inhibitory natural flavonoids and their growth inhibitory effects. Bioorganic & medicinal chemistry 20080401
Attenuation of hypertension development by scavenging methylglyoxal in fructose-treated rats. Journal of hypertension 20080401
Rapid analysis of alpha-dicarbonyl compounds by laser desorption/ionization mass spectrometry using 9-(3,4-diaminophenyl)acridine (DAA) as a reactive matrix. Rapid communications in mass spectrometry : RCM 20080401
Structures of the N47A and E109Q mutant proteins of pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii. Acta crystallographica. Section D, Biological crystallography 20080401
Determination of N epsilon-(carboxymethyl)lysine in foods and related systems. Annals of the New York Academy of Sciences 20080401
Methylglyoxal: its presence in beverages and potential scavengers. Annals of the New York Academy of Sciences 20080401
The other side of the Maillard reaction. Annals of the New York Academy of Sciences 20080401
The dicarbonyl proteome: proteins susceptible to dicarbonyl glycation at functional sites in health, aging, and disease. Annals of the New York Academy of Sciences 20080401
Isolation and partial characterization of four fluorophores formed by nonenzymatic browning of methylglyoxal and glutamine-derived ammonia. Annals of the New York Academy of Sciences 20080401
Pathophysiological role of the glyoxalase system in renal hypoxic injury. Annals of the New York Academy of Sciences 20080401
Dietary advanced glycation endproducts and oxidative stress: in vivo effects on endothelial function and adipokines. Annals of the New York Academy of Sciences 20080401
Preparation of nucleotide advanced glycation endproducts--imidazopurinone adducts formed by glycation of deoxyguanosine with glyoxal and methylglyoxal. Annals of the New York Academy of Sciences 20080401
Modification of vimentin: a general mechanism of nonenzymatic glycation in human skin. Annals of the New York Academy of Sciences 20080401
Cinnamon bark proanthocyanidins as reactive carbonyl scavengers to prevent the formation of advanced glycation endproducts. Journal of agricultural and food chemistry 20080326
Formation of pyrazines and a novel pyrrole in Maillard model systems of 1,3-dihydroxyacetone and 2-oxopropanal. Journal of agricultural and food chemistry 20080326
Immunochemical detection of Nepsilon-(carboxyethyl)lysine using a specific antibody. Journal of immunological methods 20080320
Isolation by HPLC and characterisation of the bioactive fraction of New Zealand manuka (Leptospermum scoparium) honey. Carbohydrate research 20080317
Modification of casein by the lipid oxidation product malondialdehyde. Journal of agricultural and food chemistry 20080312
Methylglyoxal and high glucose co-treatment induces apoptosis or necrosis in human umbilical vein endothelial cells. Journal of cellular biochemistry 20080301
Characterization of organosulfates from the photooxidation of isoprene and unsaturated fatty acids in ambient aerosol using liquid chromatography/(-) electrospray ionization mass spectrometry. Journal of mass spectrometry : JMS 20080301
Analysis and biological relevance of advanced glycation end-products of DNA in eukaryotic cells. The FEBS journal 20080301
Glyoxalase-1 prevents mitochondrial protein modification and enhances lifespan in Caenorhabditis elegans. Aging cell 20080301
Metabolism of halophilic archaea. Extremophiles : life under extreme conditions 20080301
Advanced glycation of fibronectin impairs vascular repair by endothelial progenitor cells: implications for vasodegeneration in diabetic retinopathy. Investigative ophthalmology & visual science 20080301
Different patterns of in vivo pro-oxidant states in a set of cancer- or aging-related genetic diseases. Free radical biology & medicine 20080215
The tandem of free radicals and methylglyoxal. Chemico-biological interactions 20080215
Methylglyoxal induces prostaglandin E2 production in rat mesangial cells. The Kobe journal of medical sciences 20080208
Energy metabolism, altered proteins, sirtuins and ageing: converging mechanisms? Biogerontology 20080201
Effect of methylglyoxal modification on stress-induced aggregation of client proteins and their chaperoning by human alphaA-crystallin. The Biochemical journal 20080201
Protein glycation and methylglyoxal metabolism in yeast: finding peptide needles in protein haystacks. FEMS yeast research 20080201
Role of GldA in dihydroxyacetone and methylglyoxal metabolism of Escherichia coli K12. FEMS microbiology letters 20080201
Antiglycation effect of gliclazide on in vitro AGE formation from glucose and methylglyoxal. Experimental biology and medicine (Maywood, N.J.) 20080201
Innovative technologies: Transportation fuels on the table. Environmental health perspectives 20080201
Protective effect of lipoic acid against methylglyoxal-induced oxidative stress in LLC-PK(1) cells. Journal of nutritional science and vitaminology 20080201
Pyridoxamine protects proteins from functional damage by 3-deoxyglucosone: mechanism of action of pyridoxamine. Biochemistry 20080122
Catalysis and structural properties of Leishmania infantum glyoxalase II: trypanothione specificity and phylogeny. Biochemistry 20080108
Methylglyoxal causes strong weakening of detoxifying capacity and apoptotic cell death in rat hippocampal neurons. The international journal of biochemistry & cell biology 20080101
Effects of advanced glycation end product modification on proximal tubule epithelial cell processing of albumin. American journal of nephrology 20080101
The structural modification of DNA nucleosides by nonenzymatic glycation: an in vitro study based on the reactions of glyoxal and methylglyoxal with 2'-deoxyguanosine. Analytical and bioanalytical chemistry 20080101
AGE-receptor-1 counteracts cellular oxidant stress induced by AGEs via negative regulation of p66shc-dependent FKHRL1 phosphorylation. American journal of physiology. Cell physiology 20080101
The implausibility of metabolic cycles on the prebiotic Earth. PLoS biology 20080101
Methylglyoxal: its presence and potential scavengers. Asia Pacific journal of clinical nutrition 20080101
Radiolabeling rhesus monkey CD34+ hematopoietic and mesenchymal stem cells with 64Cu-pyruvaldehyde-bis(N4-methylthiosemicarbazone) for microPET imaging. Molecular imaging 20080101
Distribution of glyoxalase I polymorphism among Zuni Indians: the Zuni Kidney Project. Journal of diabetes and its complications 20080101
[Role of methyl glyoxal and glyoxalase in diabetes and tumor growth]. Voprosy onkologii 20080101
Special issue on methylglyoxal. Preface. Drug metabolism and drug interactions 20080101
Molecular enzymology of the glyoxalase system. Drug metabolism and drug interactions 20080101
Microbial glyoxalase enzymes: metalloenzymes controlling cellular levels of methylglyoxal. Drug metabolism and drug interactions 20080101
An overview on the role of methylglyoxal and glyoxalases in plants. Drug metabolism and drug interactions 20080101
Methylglyoxal and glucose metabolism: a historical perspective and future avenues for research. Drug metabolism and drug interactions 20080101
Methylglyoxal, diabetes mellitus and diabetic complications. Drug metabolism and drug interactions 20080101
Protein and nucleotide damage by glyoxal and methylglyoxal in physiological systems--role in ageing and disease. Drug metabolism and drug interactions 20080101
Free radical generation by methylglyoxal in tissues. Drug metabolism and drug interactions 20080101
A brief critical overview of the biological effects of methylglyoxal and further evaluation of a methylglyoxal-based anticancer formulation in treating cancer patients. Drug metabolism and drug interactions 20080101
Plasma alpha-oxoaldehyde levels in diabetic and nondiabetic chronic kidney disease patients. American journal of nephrology 20080101
Identification of metabolites with anticancer properties by computational metabolomics. Molecular cancer 20080101
Degradation of macromolecular tannic acid by O3/H2O2. Water science and technology : a journal of the International Association on Water Pollution Research 20080101
Systematic genetic array analysis links the Saccharomyces cerevisiae SAGA/SLIK and NuA4 component Tra1 to multiple cellular processes. BMC genetics 20080101
Structure and properties of transcriptional networks driving selenite stress response in yeasts. BMC genomics 20080101
Mitochondrial dysfunction increases oxidative stress and decreases chronological life span in fission yeast. PloS one 20080101
Differential control of Zap1-regulated genes in response to zinc deficiency in Saccharomyces cerevisiae. BMC genomics 20080101
High cell density media for Escherichia coli are generally designed for aerobic cultivations - consequences for large-scale bioprocesses and shake flask cultures. Microbial cell factories 20080101
Morphology of glomerular hematuria is reproduced in vitro by carbonyl stress. Nephron. Experimental nephrology 20080101
Gene expression profiling in hepatic tissue of newly weaned pigs fed pharmacological zinc and phytase supplemented diets. BMC genomics 20080101
The clinical relevance of assessing advanced glycation endproducts accumulation in diabetes. Cardiovascular diabetology 20080101
A novel screening protocol for the isolation of hydrogen producing Chlamydomonas reinhardtii strains. BMC plant biology 20080101
Curcumin inhibits glyoxalase 1: a possible link to its anti-inflammatory and anti-tumor activity. PloS one 20080101
Hypometabolism as a therapeutic target in Alzheimer's disease. BMC neuroscience 20080101
Experimental confirmation of the dicarbonyl route in the photo-oxidation of toluene and benzene. Environmental science & technology 20071215
Isolation, identification, and quantification of roasted coffee antibacterial compounds. Journal of agricultural and food chemistry 20071212
Accumulation of endogenous methylglyoxal impaired insulin signaling in adipose tissue of fructose-fed rats. Molecular and cellular biochemistry 20071201
High-performance liquid chromatographic determination of glyoxal and methylglyoxal in urine by prederivatization to lumazinic rings using in serial fast scan fluorimetric and diode array detectors. Analytical biochemistry 20071201
Methylglyoxal and other carbohydrate metabolites induce lanthanum-sensitive Ca2+ transients and inhibit growth in E. coli. Archives of biochemistry and biophysics 20071201
Tea polyphenol (-)-epigallocatechin-3-gallate: a new trapping agent of reactive dicarbonyl species. Chemical research in toxicology 20071201
Cells deficient in the FANC/BRCA pathway are hypersensitive to plasma levels of formaldehyde. Cancer research 20071201
Mechanisms of epithelial-mesenchymal transition of peritoneal mesothelial cells during peritoneal dialysis. Journal of Korean medical science 20071201
Current concepts in targeted therapies for the pathophysiology of diabetic microvascular complications. Vascular health and risk management 20071201
Therapeutic options and challenges for substances of abuse. Dialogues in clinical neuroscience 20071201
Alteration of glyoxalase genes expression in response to testosterone in LNCaP and PC3 human prostate cancer cells. Cancer biology & therapy 20071201
Modulation of Spc1 stress-activated protein kinase activity by methylglyoxal through inhibition of protein phosphatase in the fission yeast Schizosaccharomyces pombe. Biochemical and biophysical research communications 20071130
Advanced glycation end products and the absence of premature atherosclerosis in glycogen storage disease Ia. Journal of inherited metabolic disease 20071101
Plasma methylglyoxal and glyoxal are elevated and related to early membrane alteration in young, complication-free patients with Type 1 diabetes. Molecular and cellular biochemistry 20071101
Accumulation of free adduct glycation, oxidation, and nitration products follows acute loss of renal function. Kidney international 20071101
Proinflammatory and proapoptotic effects of methylglyoxal on neutrophils from patients with type 2 diabetes mellitus. Clinical biochemistry 20071101
Determination of glyoxal and methylglyoxal in the serum of diabetic patients by MEKC using stilbenediamine as derivatizing reagent. Electrophoresis 20071101
Glycation damage targets glutamate dehydrogenase in the rat liver mitochondrial matrix during aging. The FEBS journal 20071101
DNA damage during glycation of lysine by methylglyoxal: assessment of vitamins in preventing damage. Amino acids 20071101
Effect of solvent type on the degradation of 4-MET. Dental materials journal 20071101
Isolation and determination of alpha-dicarbonyl compounds by RP-HPLC-DAD in green and roasted coffee. Journal of agricultural and food chemistry 20071031
Determination of glyoxal and methylglyoxal in environmental and biological matrices by stir bar sorptive extraction with in-situ derivatization. Journal of chromatography. A 20071026
High glucose increases angiopoietin-2 transcription in microvascular endothelial cells through methylglyoxal modification of mSin3A. The Journal of biological chemistry 20071019
Molecular action mechanism against apoptosis by aqueous extract from guava budding leaves elucidated with human umbilical vein endothelial cell (HUVEC) model. Journal of agricultural and food chemistry 20071017
Evaluation of enhanced peritoneum permeability in methylglyoxal-treated rats as a diagnostic method for peritoneal damage. Pharmaceutical research 20071001
Methylglyoxal induces advanced glycation end product (AGEs) formation and dysfunction of PDGF receptor-beta: implications for diabetic atherosclerosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20071001
Proteomic analysis defines altered cellular redox pathways and advanced glycation end-product metabolism in glomeruli of db/db diabetic mice. American journal of physiology. Renal physiology 20071001
Oxidative stress biomarkers in four Bloom syndrome (BS) patients and in their parents suggest in vivo redox abnormalities in BS phenotype. Clinical biochemistry 20071001
Identification of differential expression of genes in hepatocellular carcinoma by suppression subtractive hybridization combined cDNA microarray. Oncology reports 20071001
Identification and determination of alpha-dicarbonyl compounds formed in the degradation of sugars. Bioscience, biotechnology, and biochemistry 20071001
Mechanisms of oxidative modification of low density lipoproteins under conditions of oxidative and carbonyl stress. Biochemistry. Biokhimiia 20071001
Allosteric coupling of two different functional active sites in monomeric Plasmodium falciparum glyoxalase I. The Journal of biological chemistry 20070928
Direct observation of aminyl radical intermediate during single-crystal to single-crystal photoinduced Orton rearrangement. The journal of physical chemistry. B 20070906
Prevention of oxidative damage that contributes to the loss of bioenergetic capacity in ageing skin. Experimental gerontology 20070901
Enzymatic characteristics of an aldo-keto reductase family protein (AKR1C15) and its localization in rat tissues. Archives of biochemistry and biophysics 20070901
Discovery of alpha-aminoazaheterocycle-methylglyoxal adducts as a new class of high-affinity inhibitors of cystic fibrosis transmembrane conductance regulator chloride channels. The Journal of pharmacology and experimental therapeutics 20070901
Evidence for in vivo scavenging by aminoguanidine of formaldehyde produced via semicarbazide-sensitive amine oxidase-mediated deamination. The Journal of pharmacology and experimental therapeutics 20070901
The high-osmolarity glycerol response pathway in the human fungal pathogen Candida glabrata strain ATCC 2001 lacks a signaling branch that operates in baker's yeast. Eukaryotic cell 20070901
Role of N-(carboxymethyl)lysine in the development of ischemic heart disease in type 2 diabetes mellitus. Journal of clinical biochemistry and nutrition 20070901
A thermolyzed diet increases oxidative stress, plasma alpha-aldehydes and colonic inflammation in the rat. Chemico-biological interactions 20070830
A combined experimental and theoretical study of the reaction between methylglyoxal and OH/OD radical: OH regeneration. Physical chemistry chemical physics : PCCP 20070821
Methylglyoxal suppresses TNF-alpha-induced NF-kappaB activation by inhibiting NF-kappaB DNA-binding. Biochemical pharmacology 20070815
Analysis of DNA-bound advanced glycation end-products by LC and mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070801
Plasma protein advanced glycation end products, carboxymethyl cysteine, and carboxyethyl cysteine, are elevated and related to nephropathy in patients with diabetes. Molecular and cellular biochemistry 20070801
Comparison of results of the CellTiter Blue, the tetrazolium (3-[4,5-dimethylthioazol-2-yl]-2,5-diphenyl tetrazolium bromide), and the lactate dehydrogenase assay applied in brain cells after exposure to advanced glycation endproducts. Toxicology in vitro : an international journal published in association with BIBRA 20070801
Methylglyoxal-induced fibronectin gene expression through Ras-mediated NADPH oxidase activation in renal mesangial cells. Nephrology (Carlton, Vic.) 20070801
Biochemical characterization of Leishmania major aquaglyceroporin LmAQP1: possible role in volume regulation and osmotaxis. Molecular microbiology 20070801
Chk2 kinase is required for methylglyoxal-induced G2/M cell-cycle checkpoint arrest: implication of cell-cycle checkpoint regulation in diabetic oxidative stress signaling. Genes to cells : devoted to molecular & cellular mechanisms 20070801
Screening of genes related to methylglyoxal susceptibility. Journal of microbiology (Seoul, Korea) 20070801
Metal ion activation of S-adenosylmethionine decarboxylase reflects cation charge density. Biochemistry 20070710
Methylglyoxal impairs glucose metabolism and leads to energy depletion in neuronal cells--protection by carbonyl scavengers. Neurobiology of aging 20070701
Free glutamine as a major precursor of brown products and fluorophores in Maillard reaction systems. Amino acids 20070701
Alpha-oxoaldehydes in haemodialysis solution. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20070701
Reactive oxygen species as a signal in glucose-stimulated insulin secretion. Diabetes 20070701
Isolation, purification and characterization of histidino-threosidine, a novel Maillard reaction protein crosslink from threose, lysine and histidine. Archives of biochemistry and biophysics 20070701
Pyridine nucleotide redox abnormalities in diabetes. Antioxidants & redox signaling 20070701
Less-oxidative hemodialysis solution rendered by cathode-side application of electrolyzed water. Hemodialysis international. International Symposium on Home Hemodialysis 20070701
Delta1-pyrroline-5-carboxylic acid formed by proline dehydrogenase from the Bacillus subtilis ssp. natto expressed in Escherichia coli as a precursor for 2-acetyl-1-pyrroline. Journal of agricultural and food chemistry 20070627
Evaluation of the contact and respiratory sensitization potential of volatile organic compounds generated by simulated indoor air chemistry. Toxicological sciences : an official journal of the Society of Toxicology 20070601
Glutathione levels in blood from ataxia telangiectasia patients suggest in vivo adaptive mechanisms to oxidative stress. Clinical biochemistry 20070601
L-Carnitine inhibits protein glycation in vitro and in vivo: evidence for a role in diabetic management. Acta diabetologica 20070601
Attenuation of hypertension development by aminoguanidine in spontaneously hypertensive rats: role of methylglyoxal. American journal of hypertension 20070601
Simultaneous determination of ketoacids and dicarbonyl compounds, key Maillard intermediates on the generation of aged wine aroma. Journal of food science 20070601
Methylglyoxal and advanced glycation endproducts: new therapeutic horizons? Recent patents on cardiovascular drug discovery 20070601
Metformin prevents methylglyoxal-induced apoptosis of mouse Schwann cells. Biochemical and biophysical research communications 20070525
Structure-reactivity relationships of flavan-3-ols on product generation in aqueous glucose/glycine model systems. Journal of agricultural and food chemistry 20070502
Methylglyoxal inhibits glycation-mediated loss in chaperone function and synthesis of pentosidine in alpha-crystallin. Experimental eye research 20070501
Advanced glycation endproducts: what is their relevance to diabetic complications? Diabetes, obesity & metabolism 20070501
The conformation of acetylated virginiamycin M1 and virginiamycin M1 in explicit solvents. Biochimica et biophysica acta 20070501
Methyl glyoxal elevation is associated with oxidative stress in rheumatoid arthritis. Free radical research 20070501
Increase of intracellular methylglyoxal levels as a mode of action of retinoids against psoriasis. Dermatology online journal 20070501
The involvement of lipid radical cycles and the adenine nucleotide translocator in neurodegenerative diseases. Journal of Alzheimer's disease : JAD 20070501
Aged garlic extract and S-allyl cysteine prevent formation of advanced glycation endproducts. European journal of pharmacology 20070430
The effect of chemical modification of amino acid side-chains on collagen degradation by enzymes. Journal of biomedical materials research. Part B, Applied biomaterials 20070401
Dietary restriction, glycolysis, hormesis and ageing. Biogerontology 20070401
Genistein protects methylglyoxal-induced oxidative DNA damage and cell injury in human mononuclear cells. Toxicology in vitro : an international journal published in association with BIBRA 20070401
The sugar model: autocatalytic activity of the triose-ammonia reaction. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20070401
The anticonvulsant activity of acetone, the major ketone body in the ketogenic diet, is not dependent on its metabolites acetol, 1,2-propanediol, methylglyoxal, or pyruvic acid. Epilepsia 20070401
Reducing the formation of glucose degradation products in peritoneal dialysis solutions by ultrahigh temperature ohmic heating. Molecular nutrition & food research 20070401
Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging. The journals of gerontology. Series A, Biological sciences and medical sciences 20070401
Aldehydes and disturbance of carbohydrate metabolism: some consequences and possible approaches to its normalization. Archives of physiology and biochemistry 20070401
Complexes of atmospheric alpha-dicarbonyls with water: FTIR matrix isolation and theoretical study. The journal of physical chemistry. A 20070329
13C and 1H NMR studies of ionizations and hydrogen bonding in chymotrypsin-glyoxal inhibitor complexes. The Journal of biological chemistry 20070316
Methylglyoxal inhibits the binding step of collagen phagocytosis. The Journal of biological chemistry 20070316
Effect of pseudophosphorylation and cross-linking by lipid peroxidation and advanced glycation end product precursors on tau aggregation and filament formation. The Journal of biological chemistry 20070309
Synthesis of 1-piperideine-6-carboxylic acid produced by L-lysine-epsilon-aminotransferase from the Streptomyces clavuligerus gene expressed in Escherichia coli. Journal of agricultural and food chemistry 20070307
Apoptotic signaling in methylglyoxal-treated human osteoblasts involves oxidative stress, c-Jun N-terminal kinase, caspase-3, and p21-activated kinase 2. Journal of cellular biochemistry 20070301
Escherichia coli glyoxalase II is a binuclear zinc-dependent metalloenzyme. Archives of biochemistry and biophysics 20070301
The impact of glycation on apolipoprotein A-I structure and its ability to activate lecithin:cholesterol acyltransferase. Diabetologia 20070301
Glycation of low-density lipoprotein results in the time-dependent accumulation of cholesteryl esters and apolipoprotein B-100 protein in primary human monocyte-derived macrophages. The FEBS journal 20070301
Advanced glycation endproduct induces ROS accumulation, apoptosis, MAP kinase activation and nuclear O-GlcNAcylation in human cardiac myocytes. Life sciences 20070220
Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription. Cell 20070209
Changes in the volatile composition of a semihard ewe milk cheese induced by high-pressure treatment of 300 MPa. Journal of agricultural and food chemistry 20070207
Convenient synthesis of GOLD and MOLD and identification of their oxidation products in vitro and in vivo. Amino acids 20070201
Methylglyoxal-derived beta-carbolines formed from tryptophan and its derivates in the Maillard reaction. Amino acids 20070201
Can ageing be prevented by dietary restriction? Mechanisms of ageing and development 20070201
Icodextrin peritoneal transport in vitro: effect of sodium deoxycholate, glucose, and methylglyoxal. Artificial organs 20070201
Proline organocatalysis as a new tool for the asymmetric synthesis of ulosonic acid precursors. Chemical communications (Cambridge, England) 20070107
Age- and stage-dependent glyoxalase I expression and its activity in normal and Alzheimer's disease brains. Neurobiology of aging 20070101
The dual face of endogenous alpha-aminoketones: pro-oxidizing metabolic weapons. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070101
Characterization and functional validation of glyoxalase II from rice. Protein expression and purification 20070101
A transcriptome analysis of isoamyl alcohol-induced filamentation in yeast reveals a novel role for Gre2p as isovaleraldehyde reductase. FEMS yeast research 20070101
Detection and identification of arginine modifications on methylglyoxal-modified ribonuclease by mass spectrometric analysis. Journal of mass spectrometry : JMS 20070101
Effects of high pressure treatment on volatile profile during ripening of ewe milk cheese. Journal of dairy science 20070101
Agmatine transport into spinal nerve terminals is modulated by polyamine analogs. Journal of neurochemistry 20070101
Case-control and family-based association studies of candidate genes in autistic disorder and its endophenotypes: TPH2 and GLO1. BMC medical genetics 20070101
Impact of 3,4-dideoxyglucosone-3-ene (3,4-DGE) on cytotoxicity of acidic heat-sterilized peritoneal dialysis fluid. Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 20070101
Effect of aldehydes derived from oxidative deamination and oxidative stress on beta-amyloid aggregation; pathological implications to Alzheimer's disease. Journal of neural transmission (Vienna, Austria : 1996) 20070101
Evaluation of toxicity of the mycotoxin citrinin using yeast ORF DNA microarray and Oligo DNA microarray. BMC genomics 20070101
Selective prediction of interaction sites in protein structures with THEMATICS. BMC bioinformatics 20070101
Beta-D-glucoside utilization by Mycoplasma mycoides subsp. mycoides SC: possible involvement in the control of cytotoxicity towards bovine lung cells. BMC microbiology 20070101
AGEs and methylglyoxal induce apoptosis and expression of Mac-1 on neutrophils resulting in platelet-neutrophil aggregation. Thrombosis research 20070101
Identification of regulatory network topological units coordinating the genome-wide transcriptional response to glucose in Escherichia coli. BMC microbiology 20070101
Endogenous alpha-oxoaldehydes and formation of protein and nucleotide advanced glycation endproducts in tissue damage. Novartis Foundation symposium 20070101
Radical generation by the non-enzymatic reaction of methylglyoxal and hydrogen peroxide. Redox report : communications in free radical research 20070101
Systematic evaluation of objective functions for predicting intracellular fluxes in Escherichia coli. Molecular systems biology 20070101
Oxidative stress and diabetic retinopathy. Experimental diabetes research 20070101
Inhibition of advanced glycation and absence of galectin-3 prevent blood-retinal barrier dysfunction during short-term diabetes. Experimental diabetes research 20070101
Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation. Arthritis research & therapy 20070101
Role of advanced glycation end products in hypertension and atherosclerosis: therapeutic implications. Cell biochemistry and biophysics 20070101
Factors affecting icodextrin peritoneal transport in vitro. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20070101
Immunohistochemical study of N-epsilon-carboxymethyl lysine (CML) in human brain: relation to vascular dementia. BMC neurology 20070101
Ras activation modulates methylglyoxal-induced mesangial cell apoptosis through superoxide production. Renal failure 20070101
Genome-wide interacting effects of sucrose and herbicide-mediated stress in Arabidopsis thaliana: novel insights into atrazine toxicity and sucrose-induced tolerance. BMC genomics 20070101
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress. Journal of biology 20070101
Advanced glycation: a novel outlook on atherosclerosis. Current pharmaceutical design 20070101
Cellular signaling and potential new treatment targets in diabetic retinopathy. Experimental diabetes research 20070101
[Crystalline silica can induce oxidative stress by inhibiting glyoxalase system in bronchial epithelial cells]. Giornale italiano di medicina del lavoro ed ergonomia 20070101
The role of glucose metabolism and glucose-associated signalling in cancer. Perspectives in medicinal chemistry 20070101
Investigations on the promoting effect of ammonium hydrogencarbonate on the formation of acrylamide in model systems. Journal of agricultural and food chemistry 20061227
Site-selective modifications of arginine residues in human hemoglobin induced by methylglyoxal. Biochemistry 20061226
Heterogeneous reactions of methylglyoxal in acidic media: implications for secondary organic aerosol formation. Environmental science & technology 20061215
Trypanothione-dependent glyoxalase I in Trypanosoma cruzi. The Biochemical journal 20061201
Oxidation of acetylacetone catalyzed by horseradish peroxidase in the absence of hydrogen peroxide. Biochimica et biophysica acta 20061201
Yeast protein glycation in vivo by methylglyoxal. Molecular modification of glycolytic enzymes and heat shock proteins. The FEBS journal 20061201
Potential inplications of endogenous aldehydes in beta-amyloid misfolding, oligomerization and fibrillogenesis. Journal of neurochemistry 20061201
Methylglyoxal in food and living organisms. Molecular nutrition & food research 20061201
Trapping reactions of reactive carbonyl species with tea polyphenols in simulated physiological conditions. Molecular nutrition & food research 20061201
Suppression of AGE precursor formation following unilateral ureteral obstruction in mouse kidneys by transgenic expression of alpha-dicarbonyl/L-xylulose reductase. Bioscience, biotechnology, and biochemistry 20061201
Methylglyoxal, oxidative stress, and hypertension. Canadian journal of physiology and pharmacology 20061201
Fructose-induced peroxynitrite production is mediated by methylglyoxal in vascular smooth muscle cells. Life sciences 20061125
Alpha,beta-dicarbonyl reduction by Saccharomyces D-arabinose dehydrogenase. Biochimica et biophysica acta 20061101
Use of solid-phase microextraction to detect and quantify gas-phase dicarbonyls in indoor environments. Journal of chromatography. A 20061027
Oligomer formation in evaporating aqueous glyoxal and methyl glyoxal solutions. Environmental science & technology 20061015
Outside-in trimming of humic substances during ozonation in a membrane contactor. Environmental science & technology 20061015
Methylglyoxal is an intermediate in the biosynthesis of 6-deoxy-5-ketofructose-1-phosphate: a precursor for aromatic amino acid biosynthesis in Methanocaldococcus jannaschii. Biochemistry 20061010
Methylglyoxal bypass identified as source of chiral contamination in l(+) and d(-)-lactate fermentations by recombinant Escherichia coli. Biotechnology letters 20061001
Towards the control and inhibition of glycation-the role of the guanidine reaction center with aldehydic and diketonic dicarbonyls. A mass spectrometry study. Journal of mass spectrometry : JMS 20061001
Argpyrimidine-modified Heat shock protein 27 in human non-small cell lung cancer: a possible mechanism for evasion of apoptosis. Cancer letters 20060928
Epicatechin carbonyl-trapping reactions in aqueous maillard systems: Identification and structural elucidation. Journal of agricultural and food chemistry 20060920
Glyoxalase II, a detoxifying enzyme of glycolysis byproduct methylglyoxal and a target of p63 and p73, is a pro-survival factor of the p53 family. The Journal of biological chemistry 20060908
Cumene peroxide and Fe(2+)-ascorbate-induced lipid peroxidation and effect of phosphoglucose isomerase. Molecular and cellular biochemistry 20060901
Effect of methylglyoxal modification and phosphorylation on the chaperone and anti-apoptotic properties of heat shock protein 27. Journal of cellular biochemistry 20060901
Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols. The Biochemical journal 20060901
Protective effects of curcumin on methylglyoxal-induced oxidative DNA damage and cell injury in human mononuclear cells. Acta pharmacologica Sinica 20060901
Benfotiamine prevents macro- and microvascular endothelial dysfunction and oxidative stress following a meal rich in advanced glycation end products in individuals with type 2 diabetes. Diabetes care 20060901
Gene expression changes related to endocrine function and decline in reproduction in fathead minnow (Pimephales promelas) after dietary methylmercury exposure. Environmental health perspectives 20060901
Protein modification in aging: an update. Experimental gerontology 20060901
Characterization of the glyoxalase I gene from the vascular wilt fungus Verticillium dahliae. Canadian journal of microbiology 20060901
Beneficial effect of low ethanol intake on the cardiovascular system: possible biochemical mechanisms. Vascular health and risk management 20060901
Dihydroxyacetone and methylglyoxal as permeants of the Plasmodium aquaglyceroporin inhibit parasite proliferation. Biochimica et biophysica acta 20060801
Upregulation of glyoxalase I fails to normalize methylglyoxal levels: a possible mechanism for biochemical changes in diabetic mouse lenses. Molecular and cellular biochemistry 20060801
Multiple evidence for an early age pro-oxidant state in Down Syndrome patients. Biogerontology 20060801
Antibodies and Fab fragments protect Cu,Zn-SOD against methylglyoxal-induced inactivation. Biochimica et biophysica acta 20060801
Carbonyl emissions from commercial cooking sources in Hong Kong. Journal of the Air & Waste Management Association (1995) 20060801
Concentrations and source characteristics of airborne carbonyl compounds measured outside urban residences. Journal of the Air & Waste Management Association (1995) 20060801
Structural and functional changes in human insulin induced by methylglyoxal. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060701
Increased dicarbonyl metabolism in endothelial cells in hyperglycemia induces anoikis and impairs angiogenesis by RGD and GFOGER motif modification. Diabetes 20060701
Methylglyoxal detoxification by an aldo-keto reductase in the cyanobacterium Synechococcus sp. PCC 7002. Microbiology (Reading, England) 20060701
Mechanisms of allosteric regulation of Trypanosoma cruzi S-adenosylmethionine decarboxylase. Biochemistry 20060627
Synthesis and study of controlled release of ibuprofen from the new acrylic type polymers. International journal of pharmaceutics 20060619
Pathological effects of glyoxalase I inhibition in SH-SY5Y neuroblastoma cells. Journal of neuroscience research 20060601
Non-enzymatic model glycation reactions--a comprehensive study of the reactivity of a modified arginine with aldehydic and diketonic dicarbonyl compounds by electrospray mass spectrometry. Journal of mass spectrometry : JMS 20060601
A novel erythrocyte-based immunoassay for simultaneous detection of both antimycobacterial antibody response and mycobacterial antigen in human serum samples of pulmonary tuberculosis and a control group of patients using 'a single probe'. FEMS immunology and medical microbiology 20060601
Mechanism of the OH-initiated oxidation of hydroxyacetone over the temperature range 236-298 K. The journal of physical chemistry. A 20060601
Oxidative modification of human ceruloplasmin by methylglyoxal: an in vitro study. Journal of biochemistry and molecular biology 20060531
Methylglyoxal impairs the insulin signaling pathways independently of the formation of intracellular reactive oxygen species. Diabetes 20060501
Does chronic glycolysis accelerate aging? Could this explain how dietary restriction works? Annals of the New York Academy of Sciences 20060501
Glyoxalase I is critical for human retinal capillary pericyte survival under hyperglycemic conditions. The Journal of biological chemistry 20060428
Analytical methods for trace levels of reactive carbonyl compounds formed in lipid peroxidation systems. Journal of pharmaceutical and biomedical analysis 20060411
Effect of site-directed mutagenesis of methylglyoxal-modifiable arginine residues on the structure and chaperone function of human alphaA-crystallin. Biochemistry 20060411
Methylglyoxal as a signal initiator for activation of the stress-activated protein kinase cascade in the fission yeast Schizosaccharomyces pombe. The Journal of biological chemistry 20060407
In vivo assessment of toxicity and pharmacokinetics of methylglyoxal. Augmentation of the curative effect of methylglyoxal on cancer-bearing mice by ascorbic acid and creatine. Toxicology and applied pharmacology 20060401
Hydrazine compounds inhibit glycation of low-density lipoproteins and prevent the in vitro formation of model foam cells from glycolaldehyde-modified low-density lipoproteins. Diabetologia 20060401
A sensitive method for the quantification of acrolein and other volatile carbonyls in ambient air. Analytical chemistry 20060401
Elevated level of methylglyoxal during diabetic ketoacidosis and its recovery phase. Diabetes & metabolism 20060401
Hydroxyalkylation of conjugated nitroalkenes with activated nonenolizable carbonyl compounds. Organic letters 20060316
Stimulation of insulin release by glyceraldehyde may not be similar to glucose. Archives of biochemistry and biophysics 20060315
Formation of amines and aldehydes from parent amino acids during thermal processing of cocoa and model systems: new insights into pathways of the strecker reaction. Journal of agricultural and food chemistry 20060308
Heat-shock protein 27 is a major methylglyoxal-modified protein in endothelial cells. FEBS letters 20060306
A possible regulatory role of 17beta-estradiol and tamoxifen on glyoxalase I and glyoxalase II genes expression in MCF7 and BT20 human breast cancer cells. Breast cancer research and treatment 20060301
The fate of glyoxal and methylglyoxal in peritoneal dialysis. Journal of mass spectrometry : JMS 20060301
Inhibition of apoptosis and reduction of intracellular pH decrease in retinal neural cell cultures by a blocker of carbonic anhydrase. Investigative ophthalmology & visual science 20060301
Carbonyl stress and NMDA receptor activation contribute to methylglyoxal neurotoxicity. Free radical biology & medicine 20060301
The sour side of sweet. Science of aging knowledge environment : SAGE KE 20060208
Antimelanoma activity of apoptogenic carbonyl scavengers. The Journal of pharmacology and experimental therapeutics 20060201
Transgenic tobacco overexpressing glyoxalase pathway enzymes grow and set viable seeds in zinc-spiked soils. Plant physiology 20060201
Reactions of a modified lysine with aldehydic and diketonic dicarbonyl compounds: an electrospray mass spectrometry structure/activity study. Journal of mass spectrometry : JMS 20060201
Specificity of the trypanothione-dependent Leishmania major glyoxalase I: structure and biochemical comparison with the human enzyme. Molecular microbiology 20060201
Interaction of Nepsilon(carboxymethyl)lysine- and methylglyoxal-modified albumin with endothelial cells and macrophages. Splice variants of RAGE may limit the responsiveness of human endothelial cells to AGEs. Thrombosis and haemostasis 20060201
Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription. Cell 20060127
Methylglyoxal comes of AGE. Cell 20060127
Reaction of HO with hydroxyacetone (HOCH2C(O)CH3): rate coefficients (233-363 K) and mechanism. Physical chemistry chemical physics : PCCP 20060114
Glycation increases human annulus fibrosus stiffness in both experimental measurements and theoretical predictions. Journal of biomechanics 20060101
Characterization of the gene encoding glyoxalase II from Leishmania donovani: a potential target for anti-parasite drugs. The Biochemical journal 20060101
Gender-related differences in advanced glycation endproducts, oxidative stress markers and nitric oxide synthases in rats. Kidney international 20060101
Identification of 4-oxo-2-hexenal and other direct mutagens formed in model lipid peroxidation reactions as dGuo adducts. Chemical research in toxicology 20060101
Time course of specific AGEs during optimised glycaemic control in type 2 diabetes. The Netherlands journal of medicine 20060101
Methylglyoxal downregulates Raf-1 protein through a ubiquitination-mediated mechanism. The international journal of biochemistry & cell biology 20060101
Novel electrochemical approach to enhanced toxicity of 4-oxo-2-nonenal vs. 4-hydroxy-2-nonenal (role of imine): oxidative stress and therapeutic modalities. Medical hypotheses 20060101
Glucose degradation products and the peritoneum--how sweet things can turn bitter. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20060101
Peritoneal injury by methylglyoxal in peritoneal dialysis. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20060101
Further testing of antiviral activity of methylglyoxal urgently needed. Medical hypotheses 20060101
Overexpression of glyoxalase system enzymes in human kidney tumor. Cancer journal (Sudbury, Mass.) 20060101
[Oxidative stress and protein glycation in diabetes mellitus]. Annales de biologie clinique 20060101
Is methylglyoxal a causative factor for hypertension development? Canadian journal of physiology and pharmacology 20060101
Unmeasured anions in metabolic acidosis: unravelling the mystery. Critical care (London, England) 20060101
Pyridoxamine inhibits maillard reactions in diabetic rat lenses. Ophthalmic research 20060101
Stimulation of suicidal erythrocyte death by methylglyoxal. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20060101
Critical role of methylglyoxal and AGE in mycobacteria-induced macrophage apoptosis and activation. PloS one 20060101
Relationships of Cysteine and Lysine residues with the substrate binding site of the mitochondrial ornithine/citrulline carrier: an inhibition kinetic approach combined with the analysis of the homology structural model. Biochimica et biophysica acta 20051210
Curcumin prevents methylglyoxal-induced oxidative stress and apoptosis in mouse embryonic stem cells and blastocysts. Journal of cellular physiology 20051201
Protein arginine methyltransferases: guardians of the Arg? Trends in biochemical sciences 20051201
Hyperglycemia potentiates carbonyl stress-induced apoptosis in naïve PC-12 cells: relationship to cellular redox and activator protease factor-1 expression. Current neurovascular research 20051201
Methylglyoxal levels in plants under salinity stress are dependent on glyoxalase I and glutathione. Biochemical and biophysical research communications 20051111
Transgenic tobacco plants overexpressing glyoxalase enzymes resist an increase in methylglyoxal and maintain higher reduced glutathione levels under salinity stress. FEBS letters 20051107
The glycolytic metabolite methylglyoxal activates Pap1 and Sty1 stress responses in Schizosaccharomyces pombe. The Journal of biological chemistry 20051104
Characterization of advanced glycation end products: mass changes in correlation to side chain modifications. Analytical biochemistry 20051101
Susceptibility to diabetic nephropathy is related to dicarbonyl and oxidative stress. Diabetes 20051101
[New aspects of diabetes]. Annales pharmaceutiques francaises 20051101
Isolation of mutagenic beta-carboline derivatives after nitrite treatment of maillard reaction mixtures and analysis of these compounds from foodstuffs and human urine. Bioscience, biotechnology, and biochemistry 20051101
Mycobacterial mutants with defective control of phagosomal acidification. PLoS pathogens 20051101
A new role of phosphoglucose isomerase. Involvement of the glycolytic enzyme in aldehyde metabolism. Biochemistry. Biokhimiia 20051101
The effects of partial thiamin deficiency and oxidative stress (i.e., glyoxal and methylglyoxal) on the levels of alpha-oxoaldehyde plasma protein adducts in Fischer 344 rats. FEBS letters 20051024
Glycated and oxidized protein degradation products are indicators of fasting and postprandial hyperglycemia in diabetes. Diabetes care 20051001
Mechanism of perturbation of integrin-mediated cell-matrix interactions by reactive carbonyl compounds and its implication for pathogenesis of diabetic nephropathy. Diabetes 20051001
Simultaneous determination of mono- and dicarboxylic acids, omega-Oxo-carboxylic acids, midchain ketocarboxylic acids, and aldehydes in atmospheric aerosol samples. Environmental science & technology 20051001
Identification of DNA adducts of methylglyoxal. Chemical research in toxicology 20051001
A novel HPLC procedure for detection and quantification of aminoacetone, a precursor of methylglyoxal, in biological samples. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050925
Gas-phase chemistry of (alpha-terpineol with ozone and OH radical: rate constants and products. Environmental science & technology 20050915
Reaction coordinate analysis for beta-diketone cleavage by the non-heme Fe2+-dependent dioxygenase Dke1. Journal of the American Chemical Society 20050907
Regioselective N-functionalization of tetraazacycloalkanes. The Journal of organic chemistry 20050902
3,4-di-deoxyglucosone-3-ene promotes leukocyte apoptosis. Kidney international 20050901
Protein glycation in Saccharomyces cerevisiae. Argpyrimidine formation and methylglyoxal catabolism. The FEBS journal 20050901
Hydrogen-bonding patterns in six derivatives of 2,4-dimethylpyrrole. Acta crystallographica. Section C, Crystal structure communications 20050901
Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation. American journal of physiology. Renal physiology 20050801
Effect of buformin and metformin on formation of advanced glycation end products by methylglyoxal. Clinica chimica acta; international journal of clinical chemistry 20050801
Vascular methylglyoxal metabolism and the development of hypertension. Journal of hypertension 20050801
Conversion of methylglyoxal to acetol by Escherichia coli aldo-keto reductases. Journal of bacteriology 20050801
Evidence for the formation of adducts and S-(carboxymethyl)cysteine on reaction of alpha-dicarbonyl compounds with thiol groups on amino acids, peptides, and proteins. Chemical research in toxicology 20050801
A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome. PLoS genetics 20050801
Suppressive effect of trehalose on acrylamide formation from asparagine and reducing saccharides. Bioscience, biotechnology, and biochemistry 20050801
Micellar catalyzed degradation of fenitrothion, an organophosphorus pesticide, in solution and soils. Environmental science & technology 20050801
Model studies on the influence of high hydrostatic pressure on the formation of glycated arginine modifications at elevated temperatures. Journal of agricultural and food chemistry 20050713
Methylglyoxal administration induces diabetes-like microvascular changes and perturbs the healing process of cutaneous wounds. Clinical science (London, England : 1979) 20050701
Effect of methylglyoxal on intracellular calcium levels and viability in renal tubular cells. Cellular signalling 20050701
Glucose degradation products downregulate ZO-1 expression in human peritoneal mesothelial cells: the role of VEGF. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20050701
Ilex paraguariensis extracts inhibit AGE formation more efficiently than green tea. Fitoterapia 20050701
Evaluation of advanced glycation end products and carbonyl compounds in patients with different conditions of oxidative stress. Molecular nutrition & food research 20050701
Advanced glycation end product precursors impair ABCA1-dependent cholesterol removal from cells. Diabetes 20050701
Emergent mechanistic diversity of enzyme-catalysed beta-diketone cleavage. The Biochemical journal 20050615
Tin-catalyzed conversion of trioses to alkyl lactates in alcohol solution. Chemical communications (Cambridge, England) 20050607
D-lactate metabolism in starved Octopus ocellatus. Journal of experimental zoology. Part A, Comparative experimental biology 20050601
Transport and metabolism of D-lactate in Jerusalem artichoke mitochondria. Biochimica et biophysica acta 20050601
Chemistry and biological effects of melanoidins and glyceraldehyde-derived pyridinium as advanced glycation end products. Annals of the New York Academy of Sciences 20050601
Dicarbonyl intermediates in the maillard reaction. Annals of the New York Academy of Sciences 20050601
Formation of alpha-aminoadipic and gamma-glutamic semialdehydes in proteins by the maillard reaction. Annals of the New York Academy of Sciences 20050601
Methylglyoxal can modify GAPDH activity and structure. Annals of the New York Academy of Sciences 20050601
Effect of glucose concentration on formation of AGEs in erythrocytes in vitro. Annals of the New York Academy of Sciences 20050601
Methylglyoxal induces apoptosis through oxidative stress-mediated activation of p38 mitogen-activated protein kinase in rat Schwann cells. Annals of the New York Academy of Sciences 20050601
Dicarbonyl stress and apoptosis of vascular cells: prevention by alphaB-crystallin. Annals of the New York Academy of Sciences 20050601
Assessment of protein function following cross-linking by alpha-dicarbonyls. Annals of the New York Academy of Sciences 20050601
Ketosis leads to increased methylglyoxal production on the Atkins diet. Annals of the New York Academy of Sciences 20050601
Methylglyoxal, glyoxal, and their detoxification in Alzheimer's disease. Annals of the New York Academy of Sciences 20050601
Evaluation of glyoxal and methylglyoxal levels in uremic patients under peritoneal dialysis. Annals of the New York Academy of Sciences 20050601
Application of semiquantitative proteomics techniques to the maillard reaction. Annals of the New York Academy of Sciences 20050601
Peptide mapping of human serum albumin modified minimally by methylglyoxal in vitro and in vivo. Annals of the New York Academy of Sciences 20050601
A common pathway for intracellular reactive oxygen species production by glycoxidative and nitroxidative stress in vascular endothelial cells and smooth muscle cells. Annals of the New York Academy of Sciences 20050601
Genotoxicity of advanced glycation end products: involvement of oxidative stress and of angiotensin II type 1 receptors. Annals of the New York Academy of Sciences 20050601
Advanced glycation end products in human cancer tissues: detection of Nepsilon-(carboxymethyl)lysine and argpyrimidine. Annals of the New York Academy of Sciences 20050601
Advanced glycation end product free adducts are cleared by dialysis. Annals of the New York Academy of Sciences 20050601
High-dose thiamine therapy counters dyslipidemia and advanced glycation of plasma protein in streptozotocin-induced diabetic rats. Annals of the New York Academy of Sciences 20050601
Proteins of Thermus thermophilus are resistant to glycation-induced protein precipitation: an evolutionary adaptation to life at extreme temperatures? Annals of the New York Academy of Sciences 20050601
Analysis of Methylglyoxal Metabolism in CHO Cells Grown in Culture. Cytotechnology 20050601
Analysis of methylglyoxal in water and biological matrices by capillary zone electrophoresis with diode array detection. Electrophoresis 20050501
Quantitative assessment of the glyoxalase pathway in Leishmania infantum as a therapeutic target by modelling and computer simulation. The FEBS journal 20050501
CD36 is not involved in scavenger receptor-mediated endocytic uptake of glycolaldehyde- and methylglyoxal-modified proteins by liver endothelial cells. Journal of biochemistry 20050501
Curcumin inhibits ROS formation and apoptosis in methylglyoxal-treated human hepatoma G2 cells. Annals of the New York Academy of Sciences 20050501
In vivo prooxidant state in Werner syndrome (WS): results from three WS patients and two WS heterozygotes. Free radical research 20050501
[Ozonolysis of methacrolein and methyl vinyl ketone in aqueous solutions]. Huan jing ke xue= Huanjing kexue 20050501
Glucosepane is a major protein cross-link of the senescent human extracellular matrix. Relationship with diabetes. The Journal of biological chemistry 20050401
Humoral methylglyoxal level reflects glycemic fluctuation. Clinical biochemistry 20050401
Aging induces cardiac diastolic dysfunction, oxidative stress, accumulation of advanced glycation endproducts and protein modification. Aging cell 20050401
The HOG MAP kinase pathway is required for the induction of methylglyoxal-responsive genes and determines methylglyoxal resistance in Saccharomyces cerevisiae. Molecular microbiology 20050401
The Wolbachia genome of Brugia malayi: endosymbiont evolution within a human pathogenic nematode. PLoS biology 20050401
The influence of various substances on the biomechanical behavior of lamina cribrosa and peripapillary sclera. Investigative ophthalmology & visual science 20050401
Aminoacetone induces oxidative modification to human plasma ceruloplasmin. Chemical research in toxicology 20050401
The annotated genome of Wolbachia from the filarial nematode Brugia malayi: what it means for progress in antifilarial medicine. PLoS medicine 20050401
Albumin antioxidant capacity is modified by methylglyoxal. Diabetes & metabolism 20050401
Characterization of advanced glycation end products for biochemical studies: side chain modifications and fluorescence characteristics. Analytical biochemistry 20050315
Unique regulation of glyoxalase I activity during osmotic stress response in the fission yeast Schizosaccharomyces pombe: neither the mRNA nor the protein level of glyoxalase I increase under conditions that enhance its activity. Archives of microbiology 20050301
Metabolic flux analysis of Escherichia coli in glucose-limited continuous culture. II. Dynamic response to famine and feast, activation of the methylglyoxal pathway and oscillatory behaviour. Microbiology (Reading, England) 20050301
Possible involvement of glutamic and/or aspartic acid residue(s) and requirement of mitochondrial integrity for the protective effect of creatine against inhibition of cardiac mitochondrial respiration by methylglyoxal. Molecular and cellular biochemistry 20050301
Peptide mapping identifies hotspot site of modification in human serum albumin by methylglyoxal involved in ligand binding and esterase activity. The Journal of biological chemistry 20050218
A H2O2-producing glyoxal oxidase is required for filamentous growth and pathogenicity in Ustilago maydis. Molecular genetics and genomics : MGG 20050201
Renal clearance of glycolaldehyde- and methylglyoxal-modified proteins in mice is mediated by mesangial cells through a class A scavenger receptor (SR-A). Diabetologia 20050201
Glycation of low-density lipoproteins by methylglyoxal and glycolaldehyde gives rise to the in vitro formation of lipid-laden cells. Diabetologia 20050201
Diagnosis of cell death induced by methylglyoxal, a metabolite derived from glycolysis, in Saccharomyces cerevisiae. FEMS microbiology letters 20050201
Maintenance of DeltapH by a butanol-tolerant mutant of Clostridium beijerinckii. Microbiology (Reading, England) 20050201
Multiple metabolic hits converge on CD36 as novel mediator of tubular epithelial apoptosis in diabetic nephropathy. PLoS medicine 20050201
Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy. The Biochemical journal 20050115
Methylglyoxal-induced nitric oxide and peroxynitrite production in vascular smooth muscle cells. Free radical biology & medicine 20050115
Methylglyoxal, a metabolite derived from glycolysis, functions as a signal initiator of the high osmolarity glycerol-mitogen-activated protein kinase cascade and calcineurin/Crz1-mediated pathway in Saccharomyces cerevisiae. The Journal of biological chemistry 20050107
The low-AGE content of low-fat vegan diets could benefit diabetics - though concurrent taurine supplementation may be needed to minimize endogenous AGE production. Medical hypotheses 20050101
The carbonyl scavengers aminoguanidine and tenilsetam protect against the neurotoxic effects of methylglyoxal. Neurotoxicity research 20050101
The pro-oxidant role of methylglyoxal in mesenteric artery smooth muscle cells. Canadian journal of physiology and pharmacology 20050101
Measurement of methylglyoxal in rat tissues by electrospray ionization mass spectrometry and liquid chromatography. Journal of pharmacological and toxicological methods 20050101
The microbial selenoproteome of the Sargasso Sea. Genome biology 20050101
Characterization of the glyoxalases of the malarial parasite Plasmodium falciparum and comparison with their human counterparts. Biological chemistry 20050101
Prospective randomized study comparing MEMID with a chop-like regimen in elderly patients with aggressive non-Hodgkin's lymphoma. Oncology 20050101
Interaction preferences across protein-protein interfaces of obligatory and non-obligatory components are different. BMC structural biology 20050101
Differential susceptibility of naive and differentiated PC-12 cells to methylglyoxal-induced apoptosis: influence of cellular redox. Current neurovascular research 20050101
Natural history of S-adenosylmethionine-binding proteins. BMC structural biology 20050101
A copper chelating agent suppresses carbonyl stress in diabetic rat lenses. Journal of diabetes and its complications 20050101
[Mechanisms of hyperglycemia development and possible methods of carbohydrate metabolism normalization (review)]. Terapevticheskii arkhiv 20050101
Take care in how you store your PD fluids: actual temperature determines the balance between reactive and non-reactive GDPs. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20050101
The gene for paroxysmal non-kinesigenic dyskinesia encodes an enzyme in a stress response pathway. Human molecular genetics 20041215
Preferential inhibition of paraoxonase activity of human paraoxonase 1 by negatively charged lipids. Journal of lipid research 20041201
L-2-oxothiazolidine-4-carboxylic acid reduces in vitro cytotoxicity of glucose degradation products. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20041201
Spectroscopic studies of methylglyoxal in water and dimethylsulfoxide. Bioorganic chemistry 20041201
Differential expression of receptors for advanced glycation end-products in peritoneal mesothelial cells exposed to glucose degradation products. Clinical and experimental immunology 20041201
Increased methylglyoxal and advanced glycation end products in kidney from spontaneously hypertensive rats. Kidney international 20041201
Processing of protein glycation, oxidation and nitrosation adducts in the liver and the effect of cirrhosis. Journal of hepatology 20041201
Conventional antibody against Nepsilon-(carboxymethyl)lysine (CML) shows cross-reaction to Nepsilon-(carboxyethyl)lysine (CEL): immunochemical quantification of CML with a specific antibody. Journal of biochemistry 20041201
Determination of methylglyoxal in ruminal fluid by high-performance liquid chromatography using fluorometric detection. Journal of agricultural and food chemistry 20041117
Effects of 1,3-butadiene, isoprene, and their photochemical degradation products on human lung cells. Environmental health perspectives 20041101
Gender- and age-related distinctions for the in vivo prooxidant state in Fanconi anaemia patients. Carcinogenesis 20041001
The cytotoxic mechanism of glyoxal involves oxidative stress. Biochemical pharmacology 20041001
Preparation and quantification of methylglyoxal in human plasma using reverse-phase high-performance liquid chromatography. Clinical biochemistry 20041001
Enhanced degradation and decreased stability of eye lens alpha-crystallin upon methylglyoxal modification. Experimental eye research 20041001
Methotrexate inhibits the glyoxalase system in vivo in children with acute lymphoid leukaemia. European journal of cancer (Oxford, England : 1990) 20041001
Degradation of tert-butyl alcohol in dilute aqueous solution by an O3/UV process. Environmental science & technology 20041001
Toxic concentrations of exogenously supplied methylglyoxal in hybridoma cell culture. Cytotechnology 20041001
Mechanism and kinetics of the reaction of OH radicals with glyoxal and methylglyoxal: a quantum chemistry + CVT/SCT approach. Chemphyschem : a European journal of chemical physics and physical chemistry 20040920
Mechanism of 4-(beta-D-ribofuranosyl)aminobenzene 5'-phosphate synthase, a key enzyme in the methanopterin biosynthetic pathway. The Journal of biological chemistry 20040917
Entropy effects on protein hinges: the reaction catalyzed by triosephosphate isomerase. Biochemistry 20040914
Long-term exposure to new peritoneal dialysis solutions: Effects on the peritoneal membrane. Kidney international 20040901
Genomic damage in end-stage renal failure: potential involvement of advanced glycation end products and carbonyl stress. Seminars in nephrology 20040901
Identification of a maize kernel stress-related protein and its effect on aflatoxin accumulation. Phytopathology 20040901
Evolutionary links as revealed by the structure of Thermotoga maritima S-adenosylmethionine decarboxylase. The Journal of biological chemistry 20040806
Acceleration of nucleophilic attack on an organophosphorothioate neurotoxin, fenitrothion, by reactive counterion cationic micelles. Regioselectivity as a probe of substrate orientation within the micelle. Langmuir : the ACS journal of surfaces and colloids 20040803
Functional characterisation of glyoxalase I from the fungal wheat pathogen Stagonospora nodorum. Current genetics 20040801
N-Terminal pyrazinones: a new class of peptide-bound advanced glycation end-products. Amino acids 20040801
Influence of irradiation and storage on the quality of ready-to-eat turkey breast rolls. Poultry science 20040801
Methylglyoxal induces apoptosis through activation of p38 MAPK in rat Schwann cells. Biochemical and biophysical research communications 20040730
Hydrothermal upgrading of biomass to biofuel; studies on some monosaccharide model compounds. Carbohydrate research 20040712
Methylglyoxal: a stimulus to neutrophil oxygen radical production in chronic renal failure? Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040701
Crystal structure of the schiff base intermediate prior to decarboxylation in the catalytic cycle of aspartate alpha-decarboxylase. Journal of molecular biology 20040625
Interaction between methyl glyoxal and ascorbic acid: experimental and theoretical aspects. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040601
Effect of dicarbonyl modification of fibronectin on retinal capillary pericytes. Investigative ophthalmology & visual science 20040601
Glyoxalase II of African trypanosomes is trypanothione-dependent. The Journal of biological chemistry 20040521
Modulation of collagen proteolysis by chemical modification of amino acid side-chains in acellularized arteries. Biomaterials 20040501
Identification of thermostable glyoxalase I in the fission yeast Schizosaccharomyces pombe. Archives of microbiology 20040501
Methylglyoxal induces oxidative stress-dependent cell injury and up-regulation of interleukin-1beta and nerve growth factor in cultured hippocampal neuronal cells. Brain research 20040501
Endogenous DNA damage in humans: a review of quantitative data. Mutagenesis 20040501
Formation of genotoxic dicarbonyl compounds in dietary oils upon oxidation. Lipids 20040501
Effect of dicarbonyl-induced browning on alpha-crystallin chaperone-like activity: physiological significance and caveats of in vitro aggregation assays. The Biochemical journal 20040415
Mutagenic studies on histidine 98 of methylglyoxal synthase: effects on mechanism and conformational change. Biochemistry 20040406
Involvement of SSAO-mediated deamination in adipose glucose transport and weight gain in obese diabetic KKAy mice. American journal of physiology. Endocrinology and metabolism 20040401
Solid-phase microextraction for flavor analysis in Harari Khat (Catha edulis) stimulant. Journal of Zhejiang University. Science 20040401
In vitro and in vivo models for peritonitis demonstrate unchanged neutrophil migration after exposure to dialysis fluids. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040401
Tools for metabolic engineering in Escherichia coli: inactivation of panD by a point mutation. Analytical biochemistry 20040401
S-adenosylmethionine decarboxylase degradation by the 26 S proteasome is accelerated by substrate-mediated transamination. The Journal of biological chemistry 20040326
Phorbol 12-myristate 13-acetate protects Jurkat cells from methylglyoxal-induced apoptosis by preventing c-Jun N-terminal kinase-mediated leakage of cytochrome c in an extracellular signal-regulated kinase-dependent manner. Molecular pharmacology 20040301
Pyridoxamine: an extremely potent scavenger of 1,4-dicarbonyls. Chemical research in toxicology 20040301
Yeast cells display a regulatory mechanism in response to methylglyoxal. FEMS yeast research 20040301
Threonine is the best substrate for D-lactate formation in octopus tentacle. Amino acids 20040301
Two distinct distributions of F-actin are present in the hyphal apex of the oomycete Achlya bisexualis. Plant & cell physiology 20040301
Two separate pathways for d-lactate oxidation by Saccharomyces cerevisiae mitochondria which differ in energy production and carrier involvement. Biochimica et biophysica acta 20040215
Methylglyoxal induces apoptosis mediated by reactive oxygen species in bovine retinal pericytes. Journal of Korean medical science 20040201
Determination of airborne carbonyls: comparison of a thermal desorption/GC method with the standard DNPH/HPLC method. Environmental science & technology 20040201
Determination of urinary glyoxal and methylglyoxal by high-performance liquid chromatography. Clinical chemistry and laboratory medicine 20040201
Glucose toxicity effect and accumulation of methylglyoxal by the periodontal anaerobe Bacteroides forsythus. Anaerobe 20040201
Investigation of metal binding and activation of Escherichia coli glyoxalase I: kinetic, thermodynamic and mutagenesis studies. The Biochemical journal 20040115
Prevention of fructose-induced hypertension by dietary vitamins. Clinical biochemistry 20040101
Pooled analysis of alcohol dehydrogenase genotypes and head and neck cancer: a HuGE review. American journal of epidemiology 20040101
Inhibition of tumor growth by replacing glutathione with N-acetyl-L-cysteine. Medical hypotheses 20040101
Antioxidant defense in Plasmodium falciparum--data mining of the transcriptome. Malaria journal 20040101
Evidence that high-dose L-arginine may be inappropriate for use by diabetic patients as a prophylactic blocker of methylglyoxal glycation. Journal of biomedical science 20040101
Role of rpoS in the regulation of glyoxalase III in Escherichia coli. Acta biochimica Polonica 20040101
BIOKID: randomized controlled trial comparing bicarbonate and lactate buffer in biocompatible peritoneal dialysis solutions in children [ISRCTN81137991]. BMC nephrology 20040101
Glutathione, altruistic metabolite in fungi. Advances in microbial physiology 20040101
Synergistic cytotoxicity of acidity and glucose degradation products in peritoneal dialysis fluid. Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs 20040101
Estimating genomic coexpression networks using first-order conditional independence. Genome biology 20040101
Detection and determination of glyceraldehyde-derived advanced glycation end product. BioFactors (Oxford, England) 20040101
Methylglyoxal-derived hydroimidazolone advanced glycation end-products of human lens proteins. Investigative ophthalmology & visual science 20031201
The enzymatic defence against glycation in health, disease and therapeutics: a symposium to examine the concept. Biochemical Society transactions 20031201
Glyoxalase I--structure, function and a critical role in the enzymatic defence against glycation. Biochemical Society transactions 20031201
Alpha-oxoaldehyde metabolism and diabetic complications. Biochemical Society transactions 20031201
Protecting the genome: defence against nucleotide glycation and emerging role of glyoxalase I overexpression in multidrug resistance in cancer chemotherapy. Biochemical Society transactions 20031201
Glyoxalase I inhibitors in cancer chemotherapy. Biochemical Society transactions 20031201
Anti-AGEing defences against Alzheimer's disease. Biochemical Society transactions 20031201
Role of methylglyoxal adducts in the development of vascular complications in diabetes mellitus. Biochemical Society transactions 20031201
Bacterial production of methylglyoxal: a survival strategy or death by misadventure? Biochemical Society transactions 20031201
Anti-glycation defences in yeast. Biochemical Society transactions 20031201
Accumulation of fructosyl-lysine and advanced glycation end products in the kidney, retina and peripheral nerve of streptozotocin-induced diabetic rats. Biochemical Society transactions 20031201
Advanced glycation endproduct precursor alters intracellular amyloid-beta/A beta PP carboxy-terminal fragment aggregation and cytotoxicity. Journal of Alzheimer's disease : JAD 20031201
Oxidative damage of DNA induced by methylglyoxal in vitro. Toxicology letters 20031130
Glucose degradation products (GDP) retard remesothelialization independently of D-glucose concentration. Kidney international 20031101
Use of aminoguanidine (Pimagedine) to prevent the formation of advanced glycation endproducts. Archives of biochemistry and biophysics 20031101
Adverse effects of dietary glycotoxins on wound healing in genetically diabetic mice. Diabetes 20031101
Oxidative damage of DNA by the reaction of amino acid with methylglyoxal in the presence of Fe(III). International journal of biological macromolecules 20031101
Scavenging system efficiency is crucial for cell resistance to ROS-mediated methylglyoxal injury. Free radical biology & medicine 20031015
Increased formation of methylglyoxal and protein glycation, oxidation and nitrosation in triosephosphate isomerase deficiency. Biochimica et biophysica acta 20031015
Metabolism, not autoxidation, plays a role in alpha-oxoaldehyde- and reducing sugar-induced erythrocyte GSH depletion: relevance for diabetes mellitus. Molecular and cellular biochemistry 20031001
Aminoacetone induces loss of ferritin ferroxidase and iron uptake activities. Free radical research 20031001
Enhancement of chaperone function of alpha-crystallin by methylglyoxal modification. Biochemistry 20030916
Rapid suppression of mitochondrial permeability transition by methylglyoxal. Role of reversible arginine modification. The Journal of biological chemistry 20030912
Methylglyoxal modifies heat shock protein 27 in glomerular mesangial cells. FEBS letters 20030911
Glycation and glycoxidation of low-density lipoproteins by glucose and low-molecular mass aldehydes. Formation of modified and oxidized particles. European journal of biochemistry 20030901
Volatile organic compounds in rural atmospheres of central Portugal. The Science of the total environment 20030901
Dietary glycotoxins correlate with circulating advanced glycation end product levels in renal failure patients. American journal of kidney diseases : the official journal of the National Kidney Foundation 20030901
Metformin inhibition of glycation processes. Diabetes & metabolism 20030901
Glyoxal and methylglyoxal levels in diabetic patients: quantitative determination by a new GC/MS method. Clinical chemistry and laboratory medicine 20030901
OH radical-initiated reaction of 3-hexene-2,5-dione: formation of methylglyoxal. Environmental science & technology 20030801
Kinetic modelling of Amadori N-(1-deoxy-D-fructos-1-yl)-glycine degradation pathways. Part I--reaction mechanism. Carbohydrate research 20030729
Kinetic modelling of Amadori N-(1-deoxy-D-fructos-1-yl)-glycine degradation pathways. Part II--kinetic analysis. Carbohydrate research 20030729
Mitochondrial phosphatidylserine decarboxylase from higher plants. Functional complementation in yeast, localization in plants, and overexpression in Arabidopsis. Plant physiology 20030701
Protective effect of creatine against inhibition by methylglyoxal of mitochondrial respiration of cardiac cells. The Biochemical journal 20030601
Fetal or neonatal low-glycotoxin environment prevents autoimmune diabetes in NOD mice. Diabetes 20030601
The molecular chaperone alpha-crystallin incorporated into red cell ghosts protects membrane Na/K-ATPase against glycation and oxidative stress. European journal of biochemistry 20030601
Identification of N epsilon-(carboxyethyl)lysine, one of the methylglyoxal-derived AGE structures, in glucose-modified protein: mechanism for protein modification by reactive aldehydes. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505
Associating protein activities with their genes: rapid identification of a gene encoding a methylglyoxal reductase in the yeast Saccharomyces cerevisiae. Yeast (Chichester, England) 20030430
Modification and inactivation of human Cu,Zn-superoxide dismutase by methylglyoxal. Molecules and cells 20030430
The polyamines spermine and spermidine protect proteins from structural and functional damage by AGE precursors: a new role for old molecules? Life sciences 20030425
Involvement of MEKK1/ERK/P21Waf1/Cip1 signal transduction pathway in inhibition of IGF-I-mediated cell growth response by methylglyoxal. Journal of cellular biochemistry 20030415
Physiological and pathological implications of semicarbazide-sensitive amine oxidase. Biochimica et biophysica acta 20030411
Oxidative deamination of benzylamine by glycoxidation. Bioorganic & medicinal chemistry 20030403
Glucose degradation products increase apoptosis of human mesothelial cells. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20030401
Accumulation of methylglyoxal in the gingival crevicular fluid of chronic periodontitis patients. Journal of clinical periodontology 20030401
Glutathione--functions and metabolism in the malarial parasite Plasmodium falciparum. Biological chemistry 20030401
New insights into protein crosslinking via the Maillard reaction: structural requirements, the effect on enzyme function, and predicted efficacy of crosslinking inhibitors as anti-ageing therapeutics. Bioorganic & medicinal chemistry 20030320
The role of dicarbonyl compounds in non-enzymatic crosslinking: a structure-activity study. Bioorganic & medicinal chemistry 20030320
Mechanism of human S-adenosylmethionine decarboxylase proenzyme processing as revealed by the structure of the S68A mutant. Biochemistry 20030304
Formation of advanced glycation end products during CAPD. American journal of kidney diseases : the official journal of the National Kidney Foundation 20030301
Pyruvoyl-dependent arginine decarboxylase from Methanococcus jannaschii: crystal structures of the self-cleaved and S53A proenzyme forms. Structure (London, England : 1993) 20030301
Methylglyoxal induces apoptosis through activation of p38 mitogen-activated protein kinase in rat mesangial cells. Kidney international 20030301
A practical method to study functional impairment of proteins by glycation and effects of inhibitors using current coagulation/fibrinolysis reagent kits. Clinical biochemistry 20030301
Acetylacetone-cleaving enzyme Dke1: a novel C-C-bond-cleaving enzyme from Acinetobacter johnsonii. The Biochemical journal 20030201
Methylglyoxal-induced glycation affects protein topography. Archives of biochemistry and biophysics 20030201
Increased serum levels of the specific AGE-compound methylglyoxal-derived hydroimidazolone in patients with type 2 diabetes. Metabolism: clinical and experimental 20030201
Up-regulation of aldose reductase by the substrate, methylglyoxal. Chemico-biological interactions 20030201
Methylglyoxal metabolism and diabetic complications: roles of aldose reductase, glyoxalase-I, betaine aldehyde dehydrogenase and 2-oxoaldehyde dehydrogenase. Chemico-biological interactions 20030201
Advanced glycation end products inhibit de novo protein synthesis and induce TGF-beta overexpression in proximal tubular cells. Kidney international 20030201
Identification of the binding site of methylglyoxal on glutathione peroxidase: methylglyoxal inhibits glutathione peroxidase activity via binding to glutathione binding sites Arg 184 and 185. Free radical research 20030201
DNA damage by carbonyl stress in human skin cells. Mutation research 20030128
A novel aldo-keto reductase from Escherichia coli can increase resistance to methylglyoxal toxicity. FEMS microbiology letters 20030121
Glyceraldehyde-3-phosphate dehydrogenase activity as an independent modifier of methylglyoxal levels in diabetes. Biochimica et biophysica acta 20030120
Dihydroxyacetone kinases in Saccharomyces cerevisiae are involved in detoxification of dihydroxyacetone. The Journal of biological chemistry 20030117
Methylglyoxal-bovine serum albumin stimulates tumor necrosis factor alpha secretion in RAW 264.7 cells through activation of mitogen-activating protein kinase, nuclear factor kappaB and intracellular reactive oxygen species formation. Archives of biochemistry and biophysics 20030115
Short term feeding of hexadienal to postnatal rats: effects on stomach aldehyde dehydrogenase. Toxicology letters 20030113
Different activity of glyoxalase system enzymes in specimens of Sparus auratus exposed to sublethal copper concentrations. Chemico-biological interactions 20030106
Glucose degradation products in PD fluids: do they disappear from the peritoneal cavity and enter the systemic circulation? Kidney international 20030101
Affinity adsorption of glucose degradation products improves the biocompatibility of conventional peritoneal dialysis fluid. Kidney international 20030101
Improved superoxide-generating system suitable for the assessment of the superoxide-scavenging ability of aqueous extracts of food constituents using ultraweak chemiluminescence. Journal of agricultural and food chemistry 20030101
Excited state complex formation between methyl glyoxal and some aromatic bio-molecules: a fluorescence quenching study. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20030101
An effective derivatization method for quantitative determination of glyoxal and methylglyoxal in plasma samples by gas chromatography/mass spectrometry. Rapid communications in mass spectrometry : RCM 20030101
Single exposure of mesothelial cells to glucose degradation products (GDPs) yields early advanced glycation end-products (AGEs) and a proinflammatory response. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20030101
Hyper-vascular change and formation of advanced glycation endproducts in the peritoneum caused by methylglyoxal and the effect of an anti-oxidant, sodium sulfite. American journal of nephrology 20030101
[Implication of methylglyoxal in diabetes mellitus]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20030101
Synthesis and biological activities of turkesterone 11alpha-acyl derivatives. Journal of insect science (Online) 20030101
Monomeric S-adenosylmethionine decarboxylase from plants provides an alternative to putrescine stimulation. Biochemistry 20021210
The botanical extracts of Achyrocline satureoides and Ilex paraguariensis prevent methylglyoxal-induced inhibition of plasminogen and antithrombin III. Life sciences 20021206
Molecular mechanisms of the cross-impact of pathological processes in combined diabetes and cancer. Research and clinical aspects. Biochemistry. Biokhimiia 20021201
Glycated proteins can enhance photooxidative stress in aged and diabetic lenses. Free radical research 20021201
Modulation of heat-shock protein 27 (Hsp27) anti-apoptotic activity by methylglyoxal modification. The Journal of biological chemistry 20021129
Methylglyoxal synthetase, enol-pyruvaldehyde, glutathione and the glyoxalase system. Journal of the American Chemical Society 20021106
Oxidative deamination of lysine residue in plasma protein of diabetic rats. Novel mechanism via the Maillard reaction. European journal of biochemistry 20021101
Possible mechanism for involvement of cysteine in aroma production in wine. Journal of agricultural and food chemistry 20021009
Semicarbazide-sensitive amine oxidase in aortic smooth muscle cells mediates synthesis of a methylglyoxal-AGE: implications for vascular complications in diabetes. Biochemical and biophysical research communications 20021004
Study of a glucose-activated anion-selective channel in rat pancreatic beta-cells. Pflugers Archiv : European journal of physiology 20021001
Concentrations of formaldehyde and other carbonyls in environments affected by incense burning. Journal of environmental monitoring : JEM 20021001
A novel beta-diketone-cleaving enzyme from Acinetobacter johnsonii: acetylacetone 2,3-oxygenase. Biochemical and biophysical research communications 20020920
Differing expression of enzymes of the glyoxalase system in superficial and invasive bladder carcinomas. European journal of cancer (Oxford, England : 1990) 20020901
Involvement of semicarbazide-sensitive amine oxidase-mediated deamination in atherogenesis in KKAy diabetic mice fed with high cholesterol diet. Diabetologia 20020901
Immunolocalization and quantification of advanced glycation end products in retinal neovascular membranes and serum: a possible role in ocular neovascularization. Current eye research 20020901
Efficient in vitro lowering of carbonyl stress by the glyoxalase system in conventional glucose peritoneal dialysis fluid. Kidney international 20020801
D-Lactate transport and metabolism in rat liver mitochondria. The Biochemical journal 20020715
Inactivation of cellular enzymes by carbonyls and protein-bound glycation/glycoxidation products. Archives of biochemistry and biophysics 20020715
Identification and quantification of major maillard cross-links in human serum albumin and lens protein. Evidence for glucosepane as the dominant compound. The Journal of biological chemistry 20020712
Alterations in renal mitochondrial respiration in response to the reactive oxoaldehyde methylglyoxal. American journal of physiology. Renal physiology 20020701
Improved insulin sensitivity is associated with restricted intake of dietary glycoxidation products in the db/db mouse. Diabetes 20020701
Methanococcus jannaschii uses a pyruvoyl-dependent arginine decarboxylase in polyamine biosynthesis. The Journal of biological chemistry 20020628
Effects of modifications of alpha-crystallin on its chaperone and other properties. The Biochemical journal 20020615
Effect of pyridoxamine on chemical modification of proteins by carbonyls in diabetic rats: characterization of a major product from the reaction of pyridoxamine and methylglyoxal. Archives of biochemistry and biophysics 20020601
Conversion of Amadori products of the Maillard reaction to N(epsilon)-(carboxymethyl)lysine by short-term heating: possible detection of artifacts by immunohistochemistry. Laboratory investigation; a journal of technical methods and pathology 20020601
New stereoselective reaction of methylglyoxal with 2-aminopyridine and adenine derivatives: formation of imino acid-nucleic base derivatives in water under mild conditions. Chemical communications (Cambridge, England) 20020521
Expression of rat liver glutathione-S-transferase GSTA5 in cell lines provides increased resistance to alkylating agents and toxic aldehydes. Chemico-biological interactions 20020520
Chromatographic assay of glycation adducts in human serum albumin glycated in vitro by derivatization with 6-aminoquinolyl-N-hydroxysuccinimidyl-carbamate and intrinsic fluorescence. The Biochemical journal 20020515
Ambient air measurement of acrolein and other carbonyls at the Oakland-San Francisco Bay Bridge toll plaza. Environmental science & technology 20020515
Substrate-induced up-regulation of aldose reductase by methylglyoxal, a reactive oxoaldehyde elevated in diabetes. Molecular pharmacology 20020501
Advanced glycation end product precursors impair epidermal growth factor receptor signaling. Diabetes 20020501
A possible regulatory role of glyoxalase I in cell viability of human prostate cancer. Urological research 20020501
Tuning of the optical and electrochemical properties of the primary donor bacteriochlorophylls in the reaction centre from Rhodobacter sphaeroides: spectroscopy and structure. Biochimica et biophysica acta 20020422
Optimization of a mist chamber (Cofer scrubber) for sampling water-soluble organics in air. Environmental science & technology 20020415
Catalysis and stability of triosephosphate isomerase from Trypanosoma brucei with different residues at position 14 of the dimer interface. Characterization of a catalytically competent monomeric enzyme. Biochemistry 20020402
Cellular oxidant stress and advanced glycation endproducts of albumin: caveats of the dichlorofluorescein assay. Archives of biochemistry and biophysics 20020401
Speciated ambient carbonyls in Rio de Janeiro, Brazil. Environmental science & technology 20020401
Qualitative determination of specific protein glycation products by matrix-assisted laser desorption/ionization mass spectrometry Peptide mapping. Journal of agricultural and food chemistry 20020327
Assessment of antibody responses to antigens of Mycobacterium tuberculosis and Cysticercus cellulosae in cerebrospinal fluid of chronic meningitis patients for definitive diagnosis as TBM/NCC by passive hemagglutination and immunoblot assays. FEMS immunology and medical microbiology 20020325
Feasibility of collection and analysis of airborne carbonyls by on-sorbent derivatization and thermal desorption. Analytical chemistry 20020315
Increased methylglyoxal and oxidative stress in hypertensive rat vascular smooth muscle cells. Hypertension (Dallas, Tex. : 1979) 20020301
Effects of thermal denaturation on protein glycation. Life sciences 20020301
Generation of superoxide anions during the reaction of guanidino compounds with methylglyoxal. Chemical & pharmaceutical bulletin 20020201
Identification of alpha-dicarbonyl scavengers for cellular protection against carbonyl stress. Biochemical pharmacology 20020201
Methylglyoxal enhances cisplatin-induced cytotoxicity by activating protein kinase Cdelta. The Journal of biological chemistry 20020125
Lipid peroxidation contributes to immune reactions associated with alcoholic liver disease. Free radical biology & medicine 20020101
Crosslinking by advanced glycation end products increases the stiffness of the collagen network in human articular cartilage: a possible mechanism through which age is a risk factor for osteoarthritis. Arthritis and rheumatism 20020101
Glucocorticoids and polyamine inhibitors synergize to kill human leukemic CEM cells. Neoplasia (New York, N.Y.) 20020101
Passive cigarette smoke and the renal glyoxalase system. Molecular and cellular biochemistry 20020101
Comparison between modifications of lens proteins resulted from glycation with methylglyoxal, glyoxal, ascorbic acid, and fructose. Journal of biochemical and molecular toxicology 20020101
Improving 1,3-propanediol production from glycerol in a metabolically engineered Escherichia coli by reducing accumulation of sn-glycerol-3-phosphate. Biotechnology progress 20020101
Glycation in diabetic neuropathy: characteristics, consequences, causes, and therapeutic options. International review of neurobiology 20020101
Regulation of the glyoxalase pathway in human brain microvascular endothelium: effects of troglitazone and tertiary butylhydroperoxide. Endothelium : journal of endothelial cell research 20020101
Potential trace metal-organic complexation in the atmosphere. TheScientificWorldJournal 20020101
Role of iron in the interaction of red blood cells with methylglyoxal. Modification of L-arginine by methylglyoxal is catalyzed by iron redox cycling. Chemico-biological interactions 20011128
Glyoxal and methylglyoxal induce lyoxal and methyglyoxal induce aggregation and inactivation of ERK in human endothelial cells. Free radical biology & medicine 20011115
Morphofunctional mitochondrial response to methylglyoxal toxicity in Bufo bufo embryos. The international journal of biochemistry & cell biology 20011101
Prolonged exposure to glucose degradation products impairs viability and function of human peritoneal mesothelial cells. Journal of the American Society of Nephrology : JASN 20011101
Troglitazone selectively inhibits glyoxalase I gene expression. Diabetologia 20011101
Continuous angiotensin II infusion increases tumour: normal blood flow ratio in colo-rectal liver metastases. British journal of cancer 20011101
Immunological detection of a novel advanced glycation end-product. Molecular medicine (Cambridge, Mass.) 20011101
Catalytic mechanism of glyoxalase I: a theoretical study. Journal of the American Chemical Society 20011024
Highly efficient Aerococcus viridans L-alpha-glycerophosphate oxidase production in the presence of H2O2-decomposing agent: purification and kinetic characterization. Applied microbiology and biotechnology 20011001
Plants synthesize ethanolamine by direct decarboxylation of serine using a pyridoxal phosphate enzyme. The Journal of biological chemistry 20010921
Carnosine, the anti-ageing, anti-oxidant dipeptide, may react with protein carbonyl groups. Mechanisms of ageing and development 20010915
Aerobic oxidation of aminoacetone, a threonine catabolite: iron catalysis and coupled iron release from ferritin. Chemical research in toxicology 20010901
Aldehyde and monocyclic aromatic hydrocarbon mixing ratios at an urban site in Las Vegas, Nevada. Journal of the Air & Waste Management Association (1995) 20010901
Polyamine regulation of the rat pro-opiomelanocortin gene expression in AtT-20 cells. Journal of neuroendocrinology 20010901
Inhibitory effects of S-nitrosoglutathione on cell proliferation and DNA synthesis: possible role of glyoxalase I inactivation. Chemico-biological interactions 20010831
Superoxide-mediated early oxidation and activation of ASK1 are important for initiating methylglyoxal-induced apoptosis process. Free radical biology & medicine 20010815
Structure of a human S-adenosylmethionine decarboxylase self-processing ester intermediate and mechanism of putrescine stimulation of processing as revealed by the H243A mutant. Biochemistry 20010814
Selective activation of apoptosis program by S-p-bromobenzylglutathione cyclopentyl diester in glyoxalase I-overexpressing human lung cancer cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20010801
High concentrations of glucose induce synthesis of argpyrimidine in retinal endothelial cells. Current eye research 20010801
Active site structure and mechanism of human glyoxalase I-an ab initio theoretical study. Journal of the American Chemical Society 20010725
Glyoxal and methylglyoxal trigger distinct signals for map family kinases and caspase activation in human endothelial cells. Free radical biology & medicine 20010701
Accumulation of methylglyoxal in anaerobically grown Escherichia coli and its detoxification by expression of the Pseudomonas putida glyoxalase I gene. Metabolic engineering 20010701
The Saccharomyces cerevisiae aldose reductase is implied in the metabolism of methylglyoxal in response to stress conditions. Current genetics 20010701
In situ analysis of methylglyoxal metabolism in Saccharomyces cerevisiae. FEBS letters 20010615
Mechanistic implications of methylglyoxal synthase complexed with phosphoglycolohydroxamic acid as observed by X-ray crystallography and NMR spectroscopy. Biochemistry 20010612
Cytotoxic action of methylglyoxal on insulin-secreting cells. Biochemical pharmacology 20010601
Evaluation of media and derivatization chemistry for six aldehydes in a passive sampler. Environmental science & technology 20010601
In vitro processing of the proproteins GrdE of protein B of glycine reductase and PrdA of D-proline reductase from Clostridium sticklandii: formation of a pyruvoyl group from a cysteine residue. European journal of biochemistry 20010601
The sugar model: catalytic flow reactor dynamics of pyruvaldehyde synthesis from triose catalyzed by poly-l-lysine contained in a dialyzer. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20010601
Argpyrimidine, a blue fluorophore in human lens proteins: high levels in brunescent cataractous lenses. Investigative ophthalmology & visual science 20010501
Genetic and biochemical characterization of a short-chain alcohol dehydrogenase from the hyperthermophilic archaeon Pyrococcus furiosus. European journal of biochemistry 20010501
A 33-kDa allergen from rice (Oryza sativa L. Japonica). cDNA cloning, expression, and identification as a novel glyoxalase I. The Journal of biological chemistry 20010406
The importance of hinge sequence for loop function and catalytic activity in the reaction catalyzed by triosephosphate isomerase. Journal of molecular biology 20010406
Suppression of the accumulation of triosephosphates and increased formation of methylglyoxal in human red blood cells during hyperglycaemia by thiamine in vitro. Journal of biochemistry 20010401
alpha-Dicarbonyls increase in the postprandial period and reflect the degree of hyperglycemia. Diabetes care 20010401
Ozone removal in the sampling of parts per billion levels of terpenoid compounds: an evaluation of different scrubber materials. Environmental science & technology 20010401
Sugar-mediated crosslinking of alpha-biotinylated-Lys to cysteamine-agarose support: a method to isolate Maillard Lys-Lys-like crosslinks. Applied biochemistry and biotechnology 20010401
Effect of methylglyoxal on mouse embryogenesis. Chang Gung medical journal 20010401
Protein glycation: creation of catalytic sites for free radical generation. Annals of the New York Academy of Sciences 20010401
2-Bromoethylamine as a potent selective suicide inhibitor for semicarbazide-sensitive amine oxidase. Biochemical pharmacology 20010315
Chromatographic quantification of argpyrimidine, a methylglyoxal-derived product in tissue proteins: comparison with pentosidine. Analytical biochemistry 20010301
Brief history of glyoxalase I and what we have learned about metal ion-dependent, enzyme-catalyzed isomerizations. Archives of biochemistry and biophysics 20010301
Expression of glyoxalase I and II in normal and breast cancer tissues. Breast cancer research and treatment 20010301
Catalase has a novel protective role against electrophile killing of Xanthomonas. Microbiology (Reading, England) 20010201
A stress-responsive glyoxalase I from the parasitic nematode Onchocerca volvulus. The Biochemical journal 20010201
Low-density lipoprotein (LDL)-induced monocyte-endothelial cell adhesion, soluble cell adhesion molecules, and autoantibodies to oxidized-LDL in chronic renal failure patients on dialysis therapy. Metabolism: clinical and experimental 20010201
Carbohydrate and amino acid degradation pathways in L-methionine/D-[13C] glucose model systems. Journal of agricultural and food chemistry 20010201
Metabolism of the 2-oxoaldehyde methylglyoxal by aldose reductase and by glyoxalase-I: roles for glutathione in both enzymes and implications for diabetic complications. Chemico-biological interactions 20010130
The crystal structure of an aldehyde reductase Y50F mutant-NADP complex and its implications for substrate binding. Chemico-biological interactions 20010130
Chemistry and pathobiology of advanced glycation end products. Contributions to nephrology 20010101
N(delta)-(5-hydroxy-4,6-dimethylpyrimidine-2-yl)-l-ornithine, a novel methylglyoxal-arginine modification in beer. Journal of agricultural and food chemistry 20010101
Microbial formation, biotechnological production and applications of 1,2-propanediol. Applied microbiology and biotechnology 20010101
The sugar model: catalysis by amines and amino acid products. Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life 20010101
Oxidation of albumin is enhanced in the presence of uremic toxins. Renal failure 20010101
Sodium sulfite and N-acetylcysteine: new additives to dialysate for inhibiting formation of glucose degradation products and advanced glycation end-products. Advances in peritoneal dialysis. Conference on Peritoneal Dialysis 20010101
Non-enzymatic glycosylation of a type I collagen matrix: effects on osteoblastic development and oxidative stress. BMC cell biology 20010101
[Molecular mechanisms of metabolic adaptation in pathological changed liver during toxic hepatitis ]. Voprosy meditsinskoi khimii 20010101
AGES in brain ageing: AGE-inhibitors as neuroprotective and anti-dementia drugs? Biogerontology 20010101
Early glycated albumin, but not advanced glycated albumin, methylglyoxal, or 3-deoxyglucosone increases the expression of PAI-1 in human peritoneal mesothelial cells. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101
Glucose degradation products in peritoneal dialysis fluids may have both local and systemic effects: a study of residual fluid and mesothelial cells. Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101
Major differences exist in the function and tissue-specific expression of human aflatoxin B1 aldehyde reductase and the principal human aldo-keto reductase AKR1 family members. The Biochemical journal 19991015
Immunological evidence for methylglyoxal-derived modifications in vivo. Determination of antigenic epitopes. The Journal of biological chemistry 19980320
Inactivation of glutathione reductase by 4-hydroxynonenal and other endogenous aldehydes. Biochemical pharmacology 19970425
Analysis of the potential carcinogenicity of coffee and its related compounds in a medium-term liver bioassay of rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19950101
The formation of methylglyoxal from triose phosphates. Investigation using a specific assay for methylglyoxal. European journal of biochemistry 19930215
Properties