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Pyridine-n-oxide

CAS No.:
694-59-7
Catalog Number:
AG0035JU
Molecular Formula:
C5H5NO
Molecular Weight:
95.0993
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
95%
In Stock USA
United States
$13
- +
25g
95%
In Stock USA
United States
$25
- +
100g
95%
In Stock USA
United States
$63
- +
500g
95%
In Stock USA
United States
$250
- +
Product Description
Catalog Number:
AG0035JU
Chemical Name:
Pyridine-n-oxide
CAS Number:
694-59-7
Molecular Formula:
C5H5NO
Molecular Weight:
95.0993
MDL Number:
MFCD11113379
IUPAC Name:
1-oxidopyridin-1-ium
InChI:
InChI=1S/C5H5NO/c7-6-4-2-1-3-5-6/h1-5H
InChI Key:
ILVXOBCQQYKLDS-UHFFFAOYSA-N
SMILES:
[O-][n+]1ccccc1
EC Number:
211-774-6
UNII:
91F12JJJ4H
NSC Number:
18250
Properties
Complexity:
50  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
95.037g/mol
Formal Charge:
0
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
95.101g/mol
Monoisotopic Mass:
95.037g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
25.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.2  
Literature
Title Journal
Substitution of the nitro group with Grignard reagents: facile arylation and alkenylation of pyridine N-oxides. Organic letters 20121102
Production of a new pyridine N-oxide by bioconversion with Cunninghamella echinulata var. elegans. Journal of bioscience and bioengineering 20121101
Enantioselective addition of cyclic enol silyl ethers to 2-alkenoyl-pyridine-N-oxides catalysed by Cu(II)-bis(oxazoline) complexes. Chemistry (Weinheim an der Bergstrasse, Germany) 20120910
Gold-catalysed cycloisomerisation reactions of 2-(2-propynyl)pyridine N-oxides leading to indolizinones. Chemical communications (Cambridge, England) 20120807
Temperature and solvent structure dependence of VO2+ complexes of pyridine-N-oxide derivatives and their interaction with human serum transferrin. Dalton transactions (Cambridge, England : 2003) 20120628
Effects of metal pyrithione antifoulants on freshwater macrophyte Lemna gibba G3 determined by image analysis. Ecotoxicology (London, England) 20120501
Mechanistic studies on direct arylation of pyridine N-oxide: evidence for cooperative catalysis between two distinct palladium centers. Journal of the American Chemical Society 20120227
Cu(I)-catalyzed oxidative cyclization of alkynyl oxiranes and oxetanes. Journal of the American Chemical Society 20120118
Photochemical activation of ruthenium(II)-pyridylamine complexes having a pyridine-N-oxide pendant toward oxygenation of organic substrates. Journal of the American Chemical Society 20111109
Radiolabeling of PAMAM dendrimers conjugated to a pyridine-N-oxide DOTA analog with ¹¹¹In: Optimization of reaction conditions and biodistribution. Journal of pharmaceutical and biomedical analysis 20111101
Synthesis of pyridine-N-oxide-borane intramolecular complexes by palladium-catalyzed reaction of 2-bromopyridine-N-oxides with alkynyltriarylborates. Organic letters 20110617
Highly enantioselective nitrone cycloadditions with 2-alkenoyl pyridine N-oxides catalyzed by Cu(II)-BOX complexes. Organic letters 20110204
Influence of polarity on the scalability and reproducibility of solvent-free microwave-assisted reactions. Combinatorial chemistry & high throughput screening 20110201
General and mild preparation of 2-aminopyridines. Organic letters 20101119
Modulation of the luminescence quantum efficiency for blue luminophor {Al(salophen)}(+) by ester-substituents. Dalton transactions (Cambridge, England : 2003) 20100227
The stability of aryl carbanions derived from pyridine N-oxide: the role of resonance in stabilizing aryl anions. Journal of the American Chemical Society 20100113
Densely packed Gd(III)-chelates with fast water exchange on a calix[4]arene scaffold: a potential MRI contrast agent. Dalton transactions (Cambridge, England : 2003) 20100107
Pyridine N-oxides as ligands in Cu-catalyzed N-arylation of imidazoles in water. Organic letters 20090806
Bioactive pyridine-N-oxide disulfides from Allium stipitatum. Journal of natural products 20090327
Molecular recognition of pyridine N-oxides in water using calix[4]pyrrole receptors. Journal of the American Chemical Society 20090311
Direct dehydrative N-pyridinylation of amides. The Journal of organic chemistry 20090206
Identification of aliphatic and aromatic tertiary N-oxide functionalities in protonated analytes via ion/molecule and dissociation reactions in an FT-ICR mass spectrometer. The Journal of organic chemistry 20090206
Lanthanide(III) complexes of pyridine-N-oxide analogues of DOTA in solution and in the solid state. A new kind of isomerism in complexes of DOTA-like ligands. Inorganic chemistry 20090119
Pyridine-N-oxide analogues of DOTA and their gadolinium(III) complexes endowed with a fast water exchange on the square-antiprismatic isomer. Inorganic chemistry 20090119
Pharmacokinetics of sorafenib in patients with renal impairment undergoing hemodialysis. International journal of clinical pharmacology and therapeutics 20090101
An EXAFS spectroscopic, large-angle X-ray scattering, and crystallographic study of hexahydrated, dimethyl sulfoxide and pyridine 1-oxide hexasolvated mercury(II) ions. Chemistry (Weinheim an der Bergstrasse, Germany) 20080101
A general and efficient 2-amination of pyridines and quinolines. The Journal of organic chemistry 20070608
2-alkenoyl pyridine N-oxides, highly efficient dienophiles for the enantioselective Cu(II)-bis(oxazoline) catalyzed Diels-Alder reaction. Organic letters 20070510
Synthesis of 2-substituted pyridines via a regiospecific alkylation, alkynylation, and arylation of pyridine N-oxides. Organic letters 20070329
Amide-N-oxide heterosynthon and amide dimer homosynthon in cocrystals of carboxamide drugs and pyridine N-oxides. Molecular pharmaceutics 20070101
Discovery of 3-methyl-N-(1-oxy-3',4',5',6'-tetrahydro-2'H-[2,4'-bipyridine]-1'-ylmethyl)benzamide (ABT-670), an orally bioavailable dopamine D4 agonist for the treatment of erectile dysfunction. Journal of medicinal chemistry 20061214
Synthesis development of a naphthyridinone p38 kinase inhibitor. Current opinion in drug discovery & development 20061101
Detection of hydrogen bonding in solution: a 2H nuclear magnetic resonance method based on rotational motion of a donor/acceptor complex. Physical chemistry chemical physics : PCCP 20060914
Regioselective synthesis of 3-(2-hydroxyaryl)pyridines via arynes and pyridine N-oxides. The Journal of organic chemistry 20060609
Pyridine N-oxide derivatives inhibit viral transactivation by interfering with NF-kappaB binding. Biochemical pharmacology 20060414
Carboxamide-pyridine N-oxide heterosynthon for crystal engineering and pharmaceutical cocrystals. Chemical communications (Cambridge, England) 20060407
Pyridine N-oxide derivatives are inhibitory to the human SARS and feline infectious peritonitis coronavirus in cell culture. The Journal of antimicrobial chemotherapy 20060301
Calculations on the group 15 intraring substituted benzenes (pyridine to bismin series) and their datively bonded oxides and sulfides. The journal of physical chemistry. A 20051013
In vitro microsomal metabolic studies on a selective mGluR5 antagonist MTEP: characterization of in vitro metabolites and identification of a novel thiazole ring opening aldehyde metabolite. Xenobiotica; the fate of foreign compounds in biological systems 20050801
Enantioselective approach to the hetisine alkaloids. Synthesis of the 3-methyl-1-aza-tricyclo[5.2.1.0(3,8)]decane core via intramolecular dipolar cycloaddition. Organic letters 20050721
Thermally induced N-to-O rearrangement of tert-N-oxides in atmospheric pressure chemical ionization and atmospheric pressure photoionization mass spectrometry: differentiation of N-oxidation from hydroxylation and potential determination of N-oxidation site. Analytical chemistry 20050601
Evidence of the electronic factor for the highly enantioselective catalytic efficiency of Cinchona-derived phase-transfer catalysts. Organic letters 20050317
1H NMR and DFT study of proton exchange in heterogeneous structures of pyridine-N-oxide/HCl/DCl/H2O. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050301
Pyridine N-oxide derivatives: unusual anti-HIV compounds with multiple mechanisms of antiviral action. The Journal of antimicrobial chemotherapy 20050201
Metal-organic rotaxane frameworks: three-dimensional polyrotaxanes from lanthanide-ion nodes, pyridinium N-oxide axles, and crown-ether wheels. Angewandte Chemie (International ed. in English) 20050128
Unique oxidation reaction of amides with pyridine-N-oxide catalyzed by ruthenium porphyrin: direct oxidative conversion of N-acyl-L-proline to N-acyl-L-glutamate. Journal of the American Chemical Society 20050126
Pyridine N-oxide and pyridine-d5 N-oxide: an electrospray/tandem mass spectrometric study carried out at high mass resolution. Rapid communications in mass spectrometry : RCM 20050101
HIV-chemotherapy and -prophylaxis: new drugs, leads and approaches. The international journal of biochemistry & cell biology 20040901
Orally active CCR5 antagonists as anti-HIV-1 agents 2: synthesis and biological activities of anilide derivatives containing a pyridine N-oxide moiety. Chemical & pharmaceutical bulletin 20040701
Inhibition of human immunodeficiency virus by a new class of pyridine oxide derivatives. Antimicrobial agents and chemotherapy 20030901
Chemical speciation of insulinomimetic VO(IV) complexes of pyridine-N-oxide derivatives: binary and ternary systems. Journal of inorganic biochemistry 20030601
CYP1A1 induction by pyridine and its metabolites in HepG2 cells. Archives of biochemistry and biophysics 20020815
Evidence for elevation of cytochrome P4502E1 (alcohol-inducible form) mRNA levels in rat kidney following pyridine administration. Biochemical and biophysical research communications 19920731
Properties