1H-Pyrazolo[4,3-b]pyridine
| Title | Journal |
|---|---|
| 4,5-Dihydro-1H-pyrazolo[3,4-d]pyrimidine containing phenothiazines as antitubercular agents. | Bioorganic & medicinal chemistry letters 20140315 |
| The design and synthesis of indazole and pyrazolopyridine based glucokinase activators for the treatment of type 2 diabetes mellitus. | Bioorganic & medicinal chemistry letters 20121201 |
| Synthesis and antioxidant evaluation of some new pyrazolopyridine derivatives. | Archiv der Pharmazie 20120201 |
| Synthesis of 2- and 2,3-substituted pyrazolo[1,5-a]pyridines: scope and mechanistic considerations of a domino direct alkynylation and cyclization of N-iminopyridinium ylides using alkenyl bromides, alkenyl iodides, and alkynes. | The Journal of organic chemistry 20111021 |
| Pyrazolopyridine inhibitors of B-RafV600E. Part 2: structure-activity relationships. | Bioorganic & medicinal chemistry letters 20110915 |
| Phosphodiesterase inhibitors. Part 1: Synthesis and structure-activity relationships of pyrazolopyridine-pyridazinone PDE inhibitors developed from ibudilast. | Bioorganic & medicinal chemistry letters 20110601 |
| Synthesis, structure, photophysical and electrochemiluminescence properties of Re(I) tricarbonyl complexes incorporating pyrazolyl-pyridyl-based ligands. | Dalton transactions (Cambridge, England : 2003) 20110514 |
| Acylation of heteroaromatic amines: facile and efficient synthesis of a new class of 1,2,3-triazolo[4,5-b]pyridine and pyrazolo[4,3-b]pyridine derivatives. | Molecules (Basel, Switzerland) 20110504 |
| Highly potent 5-aminotetrahydropyrazolopyridines: enantioselective dopamine D3 receptor binding, functional selectivity, and analysis of receptor-ligand interactions. | Journal of medicinal chemistry 20110414 |
| Discovery of NBI-77860/GSK561679, a potent corticotropin-releasing factor (CRF1) receptor antagonist with improved pharmacokinetic properties. | Bioorganic & medicinal chemistry letters 20101215 |
| Design, synthesis and bioevaluation of dihydropyrazolo[3,4-b]pyridine and benzo[4,5]imidazo[1,2-a]pyrimidine compounds as dual KSP and Aurora-A kinase inhibitors for anti-cancer agents. | Bioorganic & medicinal chemistry 20101115 |
| A myosin V inhibitor based on privileged chemical scaffolds. | Angewandte Chemie (International ed. in English) 20101102 |
| Pyrazolo[1,5-a]pyrimidine acetamides: 4-Phenyl alkyl ether derivatives as potent ligands for the 18 kDa translocator protein (TSPO). | Bioorganic & medicinal chemistry letters 20101001 |
| Pyrazolopyridazine alpha-2-delta-1 ligands for the treatment of neuropathic pain. | Bioorganic & medicinal chemistry letters 20100801 |
| Biaryl ethers as potent allosteric inhibitors of reverse transcriptase and its key mutant viruses: aryl substituted pyrazole as a surrogate for the pyrazolopyridine motif. | Bioorganic & medicinal chemistry letters 20100801 |
| Antiplatelet activity and structure-activity relationship study of Pyrazolopyridine Derivatives as potential series for treating thrombotic diseases. | Journal of atherosclerosis and thrombosis 20100730 |
| Recent advances in the development of selective, ATP-competitive inhibitors of mTOR. | Current opinion in drug discovery & development 20100701 |
| Synthesis, structural characterisation and quadruplex DNA binding studies of a new gold(III) pyrazolylpyridine complex. | Chemistry (Weinheim an der Bergstrasse, Germany) 20100322 |
| Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 1-substituent. | Bioorganic & medicinal chemistry letters 20100215 |
| Synthesis of the highly selective p38 MAPK inhibitor UR-13756 for possible therapeutic use in Werner syndrome. | Future medicinal chemistry 20100201 |
| Discovery of 3,6-dihydro-2H-pyran as a morpholine replacement in 6-aryl-1H-pyrazolo[3,4-d]pyrimidines and 2-arylthieno[3,2-d]pyrimidines: ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR). | Bioorganic & medicinal chemistry letters 20100115 |
| Novel purine and pyrazolo[3,4-d]pyrimidine inhibitors of PI3 kinase-alpha: Hit to lead studies. | Bioorganic & medicinal chemistry letters 20100115 |
| Assessment of the putative binding conformation of a pyrazolopyridine class of inhibitors of MAPKAPK2 using computational studies. | European journal of medicinal chemistry 20100101 |
| Structure-activity relationship study of EphB3 receptor tyrosine kinase inhibitors. | Bioorganic & medicinal chemistry letters 20091101 |
| Expedient synthesis of 3-alkoxymethyl- and 3-aminomethyl-pyrazolo[3,4-b]pyridines. | The Journal of organic chemistry 20090116 |
| Regio- and chemoselective metalation of chloropyrimidine derivatives with TMPMgCl x LiCl and TMP(2)Zn x 2 MgCl(2) x 2 LiCl. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090101 |
| Design and synthesis of 2-amino-pyrazolopyridines as Polo-like kinase 1 inhibitors. | Bioorganic & medicinal chemistry letters 20081015 |
| Pyrazolopyridines as a novel structural class of potent and selective PDE4 inhibitors. | Bioorganic & medicinal chemistry letters 20080715 |
| Synthesis and antiviral activity evaluation of some novel acyclic C-nucleosides. | Chemical & pharmaceutical bulletin 20080601 |
| Potent, selective, orally bioavailable inhibitors of tumor necrosis factor-alpha converting enzyme (TACE): discovery of indole, benzofuran, imidazopyridine and pyrazolopyridine P1' substituents. | Bioorganic & medicinal chemistry letters 20080315 |
| Pyrazolopyridines with potent activity against herpesviruses: effects of C5 substituents on antiviral activity. | Bioorganic & medicinal chemistry letters 20080201 |
| Synthesis of benzo[1,2-d;3,4-d']diimidazole and 1H-pyrazolo[4,3-b]pyridine as putative A2A receptor antagonists. | Organic & biomolecular chemistry 20070821 |
| Design and synthesis of pyridine-pyrazolopyridine-based inhibitors of protein kinase B/Akt. | Bioorganic & medicinal chemistry 20070315 |
| 3D-QSAR and molecular docking studies on pyrazolopyrimidine derivatives as glycogen synthase kinase-3beta inhibitors. | Journal of molecular graphics & modelling 20070301 |
| Modelling of UV-molecular spectra of several bis-pyrazolopyridines derivatives. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061101 |
| Synthesis and structure of a sodium complex of an aromatic beta-diketone and pyrazolylpyridine. | Molecules (Basel, Switzerland) 20060717 |
| Synthesis of C-6 substituted pyrazolo[1,5-a]pyridines with potent activity against herpesviruses. | Bioorganic & medicinal chemistry 20060215 |
| Development of ligands for the peripheral benzodiazepine receptor. | Current medicinal chemistry 20060101 |
| Synthesis of novel substituted 2-phenylpyrazolopyridines with potent activity against herpesviruses. | Bioorganic & medicinal chemistry 20050915 |
| New orally active PDE4 inhibitors with therapeutic potential. | Bioorganic & medicinal chemistry 20040801 |
| Synthesis of some new annulated pyrazolo-pyrido (or pyrano) pyrimidine, pyrazolopyridine and pyranopyrazole derivatives. | Acta pharmaceutica (Zagreb, Croatia) 20040601 |
| The synthesis of 4-deazaformycin A. | The Journal of organic chemistry 20030808 |
| Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness. | Surgery 20030801 |
| Non-imidazole heterocyclic histamine H3 receptor antagonists. | Bioorganic & medicinal chemistry letters 20030519 |
| Enhancement of sphingosine 1-phosphate-induced migration of vascular endothelial cells and smooth muscle cells by an EDG-5 antagonist. | Biochemical and biophysical research communications 20021206 |
| Metabolites of orally active NO-independent pyrazolopyridine stimulators of soluble guanylate cyclase. | Bioorganic & medicinal chemistry 20020601 |
| Implication of Galpha i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production. | Journal of endotoxin research 20020101 |
| NO-independent regulatory site on soluble guanylate cyclase. | Nature 20010308 |