Home Other Building Blocks Propyl 4-hydroxybenzoate

Propyl 4-hydroxybenzoate

CAS No.:
94-13-3
Catalog Number:
AG0035J5
Molecular Formula:
C10H12O3
Molecular Weight:
180.2005
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$13
- +
25g
98%
In Stock USA
United States
$19
- +
100g
98%
In Stock USA
United States
$50
- +
250g
98%
In Stock USA
United States
$70
- +
Product Description
Catalog Number:
AG0035J5
Chemical Name:
Propyl 4-hydroxybenzoate
CAS Number:
94-13-3
Molecular Formula:
C10H12O3
Molecular Weight:
180.2005
MDL Number:
MFCD00002354
IUPAC Name:
propyl 4-hydroxybenzoate
InChI:
InChI=1S/C10H12O3/c1-2-7-13-10(12)8-3-5-9(11)6-4-8/h3-6,11H,2,7H2,1H3
InChI Key:
QELSKZZBTMNZEB-UHFFFAOYSA-N
SMILES:
CCCOC(=O)c1ccc(cc1)O
UNII:
Z8IX2SC1OH
FEMA Number:
2951
RTECS Number:
DH2800000
Properties
Complexity:
160  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
180.079g/mol
Formal Charge:
0
Heavy Atom Count:
13  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
180.203g/mol
Monoisotopic Mass:
180.079g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
46.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
3  
Literature
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Effect of propyl paraben on the dipalmitoyl phosphatidic acid vesicles. Journal of colloid and interface science 20070715
Simultaneous determination of antioxidants, preservatives and sweetener additives in food and cosmetics by flow injection analysis coupled to a monolithic column. Analytica chimica acta 20070702
Effect of preservatives on ciliary beat frequency in human nasal epithelial cell culture: single versus multiple exposure. International journal of pharmaceutics 20070629
[Simultaneous determination of nine kinds of preservatives in foods by HPLC]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20070601
[Enhancement of di-n-butyl phthalate on the estrogenic activities of esters of p-hydroxybenzoic acid]. Wei sheng yan jiu = Journal of hygiene research 20070501
A novel application of Onyxtrade mark monolithic column for simultaneous determination of salicylic acid and triamcinolone acetonide by sequential injection chromatography. Talanta 20070430
Inhibition of conidia germination and mycelial growth of Botrytis cinerea by some alternative chemicals. Pakistan journal of biological sciences : PJBS 20070415
Optimization of levofloxacin analysis by RP-HPLC using multivariate calibration technique. Pakistan journal of pharmaceutical sciences 20070401
Comparison of objective and sensory skin irritations of several cosmetic preservatives. Contact dermatitis 20070301
[Simultaneous determination of phthalates and parabens in cosmetic products by gas chromatography/mass spectrometry coupled with solid phase extraction]. Se pu = Chinese journal of chromatography 20070301
Development and validation of chemometrics-assisted spectrophotometric and liquid chromatographic methods for the simultaneous determination of two multicomponent mixtures containing bronchodilator drugs. Journal of pharmaceutical and biomedical analysis 20070219
Assay of artemether, methylparaben and propylparaben in a formulated paediatric antimalarial dry suspension. Journal of pharmaceutical and biomedical analysis 20070117
Controlled drug release from pellets containing water-insoluble drugs dissolved in a self-emulsifying system. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070101
Effect estimates and methodological quality of randomized controlled trials about prevention of alveolar osteitis following tooth extraction: a systematic review. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20070101
Post-marketing assessment of content and efficacy of preservatives in artemisinin-derived antimalarial dry suspensions for paediatric use. Malaria journal 20070101
Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods. Journal of separation science 20070101
Study of hydroxy propyl guar derivative for its gelling property and it's use in the formulation of tenoxicam gels. Pakistan journal of pharmaceutical sciences 20070101
Evaluation of certain food additives and contaminants. World Health Organization technical report series 20070101
A phase III trial comparing an anionic phospholipid-based cream and aloe vera-based gel in the prevention of radiation dermatitis in pediatric patients. Radiation oncology (London, England) 20070101
Effect of formulation factors on in-vitro permeation of diclofenac from experimental and marketed aqueous eye drops through excised goat cornea. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20061201
Evaluation of xenoestrogenic potential of propylparaben in zebrafish (Danio rerio). Neuro endocrinology letters 20061201
Parabens as urinary biomarkers of exposure in humans. Environmental health perspectives 20061201
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. Journal of molecular graphics & modelling 20061101
Advantages of ultra performance liquid chromatography over high-performance liquid chromatography: comparison of different analytical approaches during analysis of diclofenac gel. Journal of separation science 20061101
Simple determination of betamethasone and chloramphenicol in a pharmaceutical preparation using a short monolithic column coupled to a sequential injection system. Journal of separation science 20061101
Flow cytometric cell cycle analysis allows for rapid screening of estrogenicity in MCF-7 breast cancer cells. Toxicology in vitro : an international journal published in association with BIBRA 20061001
Solid-phase extraction and HPLC analysis of methylparaben and propylparaben in a concentrated antibiotic suspension. Drug development and industrial pharmacy 20061001
Formation of halogenated by-products of parabens in chlorinated water. Analytica chimica acta 20060804
Causal agents of photoallergic contact dermatitis diagnosed in the national institute of dermatology of Colombia. Photodermatology, photoimmunology & photomedicine 20060801
Simultaneous analysis of antioxidants and preservatives in cosmetics by supercritical fluid extraction combined with liquid chromatography-mass spectrometry. Journal of chromatography. A 20060707
Simultaneous, stability indicating, HPLC-DAD determination of guaifenesin and methyl and propyl-parabens in cough syrup. Journal of pharmaceutical and biomedical analysis 20060607
Expression profiling of estrogen-responsive genes in breast cancer cells treated with alkylphenols, chlorinated phenols, parabens, or bis- and benzoylphenols for evaluation of estrogenic activity. Toxicology letters 20060525
Development and validation of a simple reversed-phase high-performance liquid chromatography method for the determination of testosterone in serum of males. Journal of pharmaceutical and biomedical analysis 20060503
Application and validation of chemometrics-assisted spectrophotometry and liquid chromatography for the simultaneous determination of six-component pharmaceuticals. Journal of pharmaceutical and biomedical analysis 20060503
Stability indicating simultaneous determination of domperidone (DP), methylparaben (MP) and propylparaben by high performance liquid chromatography (HPLC). Journal of pharmaceutical and biomedical analysis 20060503
HPLC determination of calcium pantothenate and two preservatives in topical cream. Journal of pharmaceutical and biomedical analysis 20060503
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Application of ecotoxicogenomics for studying endocrine disruption in vertebrates and invertebrates. Environmental health perspectives 20060401
A stability-indicating HPLC method for medroxyprogesterone acetate in bulk drug and injection formulation. Journal of pharmaceutical and biomedical analysis 20060318
Percutaneous dermal drug delivery for local pain control. Therapeutics and clinical risk management 20060301
Separation and determination of clotrimazole, methylparaben and propylparaben in pharmaceutical preparation by micellar electrokinetic chromatography. Journal of pharmaceutical and biomedical analysis 20060123
Separation and determination of terbinafine and its four impurities of similar structure using simple RP-HPLC method. Talanta 20060115
Advantages of application of UPLC in pharmaceutical analysis. Talanta 20060115
The importance of the cosolvent propylene glycol on the antimicrobial preservative efficacy of a pharmaceutical formulation by DOE-ruggedness testing. Pharmaceutical development and technology 20060101
The influence of physicochemical properties of preservative compounds on their distribution into various phases of oil in water submicron emulsion. PDA journal of pharmaceutical science and technology 20060101
Pharmaceutical excipients and the information on drug labels. Brazilian journal of otorhinolaryngology 20060101
Rapid and sensitive determination of indapamide in human blood by liquid chromatography with electrospray ionization mass spectrometric detection: application to a bioequivalence study. Die Pharmazie 20051101
A new validated method for the simultaneous determination of benzocaine, propylparaben and benzyl alcohol in a bioadhesive gel by HPLC. Journal of pharmaceutical and biomedical analysis 20051004
A comparison of performance of various analytical columns in pharmaceutical analysis: conventional C18 and high throughput C18 zorbax columns. Journal of chromatography. A 20050923
Stability indicating reversed-phase liquid chromatographic determination of metronidazole benzoate and diloxanide furoate as bulk drug and in suspension dosage form. Journal of pharmaceutical and biomedical analysis 20050915
Determination of parabens in pharmaceutical formulations by solid-phase microextraction-ion mobility spectrometry. Analytical chemistry 20050915
Impact of induced fit on ligand binding to the androgen receptor: a multidimensional QSAR study to predict endocrine-disrupting effects of environmental chemicals. Journal of medicinal chemistry 20050908
High performance liquid chromatographic determination of oxeladin citrate and oxybutynin hydrochloride and their degradation products. Farmaco (Societa chimica italiana : 1989) 20050801
A novel gradient HPLC method for simultaneous determination of ranitidine, methylparaben and propylparaben in oral liquid pharmaceutical formulation. Journal of pharmaceutical and biomedical analysis 20050715
The effects of parabens on the mechanosensitive channels of E. coli. European biophysics journal : EBJ 20050701
Propyl paraben induces potassium efflux in Escherichia coli. The Journal of antimicrobial chemotherapy 20050601
A review of the endocrine activity of parabens and implications for potential risks to human health. Critical reviews in toxicology 20050601
Simultaneous determination of preservatives (benzoic acid, sorbic acid, methylparaben and propylparaben) in foodstuffs using high-performance liquid chromatography. Journal of chromatography. A 20050506
The use of colloidal microgels as a (trans)dermal drug delivery system. International journal of pharmaceutics 20050323
Development and validation of a stability indicating HPLC method for determination of lisinopril, lisinopril degradation product and parabens in the lisinopril extemporaneous formulation. Journal of pharmaceutical and biomedical analysis 20050309
Decrease in skin permeation and antibacterial effect of parabens by a polymeric additive, poly(2-methacryloyloxyethyl phosphorylcholine-co-butylmetacrylate). Chemical & pharmaceutical bulletin 20050301
Estrogenic activity of cosmetic components in reporter cell lines: parabens, UV screens, and musks. Journal of toxicology and environmental health. Part A 20050227
Eco-friendly methodologies for the synthesis of some aromatic esters, well-known cosmetic ingredients. International journal of cosmetic science 20050201
In vitro effect of phenolic antioxidants on germination, growth and aflatoxin B accumulation by peanut Aspergillus section Flavi. Journal of applied microbiology 20050101
Liquid chromatography and chemometric-assisted spectrophotometric methods for the analysis of two multicomponent mixtures containing cough suppressant drugs. Journal of AOAC International 20050101
HPLC analysis of generic antiretroviral drugs purchased in Rwanda. Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg 20050101
Separation of preservatives in cosmetic products by micellar electrokinetic chromatography. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20041201
Simultaneous HPLC determination of ketoprofen and its degradation products in the presence of preservatives in pharmaceuticals. Journal of pharmaceutical and biomedical analysis 20041115
Compatibility of sennoside A and B with pharmaceutical excipients. Die Pharmazie 20040901
Morphometric analysis of mice uteri treated with the preservatives methyl, ethyl, propyl, and butylparaben. Toxicology and industrial health 20040901
HPLC determination of estradiol, its degradation product, and preservatives in new topical formulation Estrogel HBF. Analytical and bioanalytical chemistry 20040701
Propyl paraben inhibits voltage-dependent sodium channels and protects cardiomyocytes from ischemia-reperfusion injury. Life sciences 20040430
Measurement of anti-HIV activity of marketed vaginal products and excipients using a PBMC-based in vitro assay. Sexually transmitted diseases 20040301
Simultaneous determination of indinavir, ritonavir and saquinavir in plasma by high-performance liquid chromatography. Journal of the Formosan Medical Association = Taiwan yi zhi 20040301
Determination of combined p-hydroxy benzoic acid preservatives in a liquid pharmaceutical formulation by HPLC. Journal of pharmaceutical and biomedical analysis 20040127
[Synthesis of new mandelic acid derivatives with preservative action. Synthesis and acute toxicity study]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20040101
Preventing sexual transmission of HIV: anti-HIV bioregulatory and homeostatic components of commercial sexual lubricants. Journal of biological regulators and homeostatic agents 20040101
[In vitro susceptibility of a Staphylococcus spp. isolate to food preservatives]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20040101
Effect of UV screens and preservatives on vitellogenin and choriogenin production in male medaka (Oryzias latipes). Toxicology 20031215
Determination of cisapride, its oxidation product, propyl and butyl parabens in pharmaceutical dosage form by reversed-phase liquid chromatography. Journal of pharmaceutical and biomedical analysis 20031204
Estrogenic effect of propylparaben (propylhydroxybenzoate) in rainbow trout Oncorhynchus mykiss after exposure via food and water. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20031201
The physical stability of thermally-stressed phospholipid-based emulsions containing methyl, propyl and heptyl parabens as model drugs. International journal of pharmaceutics 20031020
Reversed-phase porous silica rods, an alternative approach to high-performance liquid chromatographic separation using the sequential injection chromatography technique. Journal of chromatography. A 20031010
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. Chemical research in toxicology 20031001
Simple high-performance liquid chromatographic assay for melphalan in perfusate, rat liver and tumour tissue. Biomedical chromatography : BMC 20031001
Determination of bifonazole in creams containing methyl- and propyl p-hydroxybenzoate by derivative spectrophotometric method. Journal of pharmaceutical and biomedical analysis 20030915
Simultaneous determination of methylparaben, propylparaben, hydrocortisone acetate and its degradation products in a topical cream by RP-HPLC. Journal of pharmaceutical and biomedical analysis 20030808
In vivo and in vitro estrogen bioactivities of alkyl parabens. Toxicology and industrial health 20030701
Potential use of antioxidants for control of growth and fumonisin production by Fusarium verticillioides and Fusarium proliferatum on whole maize grain. International journal of food microbiology 20030625
Determination of methylparaben, propylparaben, triamcinolone acetonide and its degradation product in a topical cream by RP-HPLC. Analytical and bioanalytical chemistry 20030601
Development of a multidose formulation for a humanized monoclonal antibody using experimental design techniques. AAPS pharmSci 20030601
Purification and characterization of PrbA, a new esterase from Enterobacter cloacae hydrolyzing the esters of 4-hydroxybenzoic acid (parabens). The Journal of biological chemistry 20030411
Photochemical stability of nimesulide. Journal of pharmaceutical and biomedical analysis 20030326
p-Hydroxybenzoic acid alkyl esters in Andrographis paniculata herbs, commercial extracts, and formulated products. Journal of agricultural and food chemistry 20030115
Vasoactive properties of lignocaine administered by iontophoresis in human skin. Clinical science (London, England : 1979) 20030101
Diffusion of preservatives from topical dosage forms: a comparative study. Journal of cosmetic science 20030101
Control of Aspergillus growth and aflatoxin production using antioxidants at different conditions of water activity and pH. Journal of applied microbiology 20030101
Determination of chlorpheniramine maleate and tincture ipecac in dosage form by liquid chromatography with ultraviolet detection. Journal of AOAC International 20030101
Propylparaben: physical characteristics. Profiles of drug substances, excipients, and related methodology 20030101
Effects of propyl paraben on the male reproductive system. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021201
Simultaneous determination of ofloxacin, tetrahydrozoline hydrochloride, and prednisolone acetate by high-performance liquid chromatography. Journal of chromatographic science 20020901
Intestinal absorption enhancement of the ester prodrug tenofovir disoproxil fumarate through modulation of the biochemical barrier by defined ester mixtures. Drug metabolism and disposition: the biological fate of chemicals 20020801
Derivative spectrophotometric determination of droperidol in presence of parabens. Journal of pharmaceutical and biomedical analysis 20020620
[Analysis of preservatives in cosmetics by gas chromatography]. Se pu = Chinese journal of chromatography 20020501
The effect of surface charge and partition coefficient on the chemical stability of solutes in O/W emulsions. Journal of pharmaceutical sciences 20020201
Sorption of benzoic acid, sorbic acid, benzyl alcohol, and benzalkonium chloride by flexible tubing. Pharmaceutical development and technology 20020101
Oestrogenic activity of parabens in MCF7 human breast cancer cells. The Journal of steroid biochemistry and molecular biology 20020101
Gas chromatography/mass spectrometric assay of endogenous cellular lipid peroxidation products: quantitative analysis of 9- and 10-hydroxystearic acids. Rapid communications in mass spectrometry : RCM 20020101
In vitro control of growth and fumonisin production by Fusarium verticillioides and F. proliferatum using antioxidants under different water availability and temperature regimes. Journal of applied microbiology 20020101
Comparison between capillary electrophoresis and liquid chromatography for the determination of diclofenac sodium in a pharmaceutical tablet. Journal of AOAC International 20020101
Oestrogenic activity of isobutylparaben in vitro and in vivo. Journal of applied toxicology : JAT 20020101
Spalling and sorption of tubing for peristaltic pumps. Pharmaceutical development and technology 20020101
ER-dependent estrogenic activity of parabens assessed by proliferation of human breast cancer MCF-7 cells and expression of ERalpha and PR. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20011201
Determination of dexamethasone and two excipients (creatinine and propylparaben) in injections by using UV-spectroscopy and multivariate calibrations. International journal of pharmaceutics 20011023
Inhibition of Saccharomyces cerevisiae by slow release of propyl paraben from a polymer coating. Journal of food protection 20010901
Sorption of parabens by flexible tubings. Pharmaceutical development and technology 20010801
Selective and quantitative analysis of 4-hydroxybenzoate preservatives by microemulsion electrokinetic chromatography. Journal of chromatography. A 20010727
Safety assessment of propyl paraben: a review of the published literature. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20010601
Simultaneous determination of quercetin, kaempferol and (E)-cinnamic acid in vegetative organs of Schisandra chinensis Baill. by HPLC. Journal of pharmaceutical and biomedical analysis 20010301
The first example of a paraben-dependent antibody to an Rh protein. Transfusion 20010301
Sorption of parabens by fluoropolymer or fluoropolymer laminated flexible tubing. PDA journal of pharmaceutical science and technology 20010101
[Competitive binding of some alkyl p-hydroxybenzoates to human estrogen receptor alpha and beta]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20001201
Determination of methylparaben, propylparaben and chlorpromazine in chlorpromazine hydrochloride oral solution by high-performance liquid chromatography. Journal of chromatography. B, Biomedical sciences and applications 19980410
Structure-activity relations in promotion of rat urinary bladder carcinogenesis by phenolic antioxidants. Japanese journal of cancer research : Gann 19900801
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