O-Methylhydroxylamine, HCl
| Title | Journal |
|---|---|
| Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors. | The Journal of pharmacy and pharmacology 20120801 |
| DNA cleavage induced by antitumor antibiotic leinamycin and its biological consequences. | Bioorganic & medicinal chemistry 20120715 |
| Development and validation of an LC-MS/MS method for pharmacokinetic study of methoxyamine in phase I clinical trial. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120715 |
| Trypanosoma brucei AP endonuclease 1 has a major role in the repair of abasic sites and protection against DNA-damaging agents. | DNA repair 20120102 |
| Removal of uracil by uracil DNA glycosylase limits pemetrexed cytotoxicity: overriding the limit with methoxyamine to inhibit base excision repair. | Cell death & disease 20120101 |
| Bioactivation pathways of the cannabinoid receptor 1 antagonist rimonabant. | Drug metabolism and disposition: the biological fate of chemicals 20111001 |
| Disproportionation of O-methylhydroxylamine catalyzed by aquapentacyanoferrate(II). | Inorganic chemistry 20110919 |
| DNA repair BER pathway inhibition increases cell death caused by oxidative DNA damage in Trypanosoma cruzi. | Journal of cellular biochemistry 20110801 |
| N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. | Neuro-oncology 20110501 |
| Soy isoflavones augment radiation effect by inhibiting APE1/Ref-1 DNA repair activity in non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110401 |
| Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair. | Cancer research 20110315 |
| Diphenylthiourea, a common rubber chemical, is bioactivated to potent skin sensitizers. | Chemical research in toxicology 20110114 |
| Accumulation of true single strand breaks and AP sites in base excision repair deficient cells. | Mutation research 20101210 |
| Targeting base excision repair suggests a new therapeutic strategy of fludarabine for the treatment of chronic lymphocytic leukemia. | Leukemia 20101001 |
| Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions. | DNA repair 20091102 |
| Nucleophile addition of reduced glutathione on 2-methyl-2-nitroso compound: a combined electron paramagnetic resonance spectroscopy and electrospray tandem mass spectrometry study. | Journal of the American Society for Mass Spectrometry 20091101 |
| Direct detection and quantification of abasic sites for in vivo studies of DNA damage and repair. | Nuclear medicine and biology 20091101 |
| Inhibitory properties of trapping agents: glutathione, potassium cyanide, and methoxylamine, against major human cytochrome p450 isoforms. | Drug metabolism letters 20090401 |
| Coordination of DNA mismatch repair and base excision repair processing of chemotherapy and radiation damage for targeting resistant cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090315 |
| Influence of high dietary sodium intake on the functional subtypes of alpha-adrenoceptors in the renal cortical vasculature of Wistar-Kyoto rats. | Autonomic & autacoid pharmacology 20090101 |
| The mismatch repair-mediated cell cycle checkpoint response to fluorodeoxyuridine. | Journal of cellular biochemistry 20080901 |
| [Effects of manumycin combined with methoxyamine on apoptosis in myeloid leukemia U937 cells]. | Ai zheng = Aizheng = Chinese journal of cancer 20080801 |
| Carmustine-resistant cancer cells are sensitized to temozolomide as a result of enhanced mismatch repair during the development of carmustine resistance. | Molecular pharmacology 20080701 |
| Enantioselective oxidation of O-methyl-N-hydroxylamines using monoamine oxidase N as catalyst. | Chemical communications (Cambridge, England) 20070421 |
| Ape1 regulates hematopoietic differentiation of embryonic stem cells through its redox functional domain. | Blood 20070301 |
| Combined treatment with temozolomide and methoxyamine: blocking apurininc/pyrimidinic site repair coupled with targeting topoisomerase IIalpha. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070301 |
| Role for DNA polymerase beta in response to ionizing radiation. | DNA repair 20070204 |
| Manipulation of base excision repair to sensitize ovarian cancer cells to alkylating agent temozolomide. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070101 |
| The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target. | Molecular aspects of medicine 20070101 |
| A stronger DNA damage-induced G2 checkpoint due to over-activated CHK1 in the absence of PARP-1. | Cell cycle (Georgetown, Tex.) 20061001 |
| Base excision repair of both uracil and oxidatively damaged bases contribute to thymidine deprivation-induced radiosensitization. | International journal of radiation oncology, biology, physics 20060801 |
| Methoxyamine potentiates iododeoxyuridine-induced radiosensitization by altering cell cycle kinetics and enhancing senescence. | Molecular cancer therapeutics 20060401 |
| Improved measurement of dibenzo[a,l]pyrene-induced abasic sites by the aldehyde-reactive probe assay. | Mutation research 20051230 |
| DNA repair inhibition: a selective tumour targeting strategy. | Trends in molecular medicine 20051101 |
| Development and validation of an HPLC-UV method for the analysis of methoxyamine using 4-(diethylamino)benzaldehyde as a derivatizing agent. | Journal of pharmaceutical and biomedical analysis 20050915 |
| Simultaneous retention index analysis of urinary amino acids and carboxylic acids for graphic recognition of abnormal state. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050705 |
| Enhancement of manumycin A-induced apoptosis by methoxyamine in myeloid leukemia cells. | Leukemia 20050401 |
| Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells. | Molecular cancer therapeutics 20040801 |
| Therapeutic impact of methoxyamine: blocking repair of abasic sites in the base excision repair pathway. | Current opinion in investigational drugs (London, England : 2000) 20040601 |
| Measurement of anti-cancer agent methoxyamine in plasma by tandem mass spectrometry with on-line sample extraction. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031005 |
| Role of MutSalpha in the recognition of iododeoxyuridine in DNA. | Cancer research 20030901 |
| Inhibition of base excision repair potentiates iododeoxyuridine-induced cytotoxicity and radiosensitization. | Cancer research 20030215 |
| A new sensitive HPLC assay for methoxyamine and its analogs. | Journal of pharmaceutical and biomedical analysis 20021015 |
| Base excision repair as a therapeutic target in colon cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020901 |
| Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage. | DNA repair 20020429 |
| [Biochemical diagnosis of pheochromocytoma and neuroblastomas]. | Annales de biologie clinique 20020101 |
| [Normal values of plasma methoxyamines in the setting of renal insufficiency and peri-operative stress. Consequences for the etiological diagnosis of hypertension]. | Annales d'endocrinologie 20011101 |
| DNA polymerase beta mediates protection of mammalian cells against ganciclovir-induced cytotoxicity and DNA breakage. | Cancer research 20011015 |
| Beta D305A mutant of tryptophan synthase shows strongly perturbed allosteric regulation and substrate specificity. | Biochemistry 20010626 |
| Methoxyamine potentiates DNA single strand breaks and double strand breaks induced by temozolomide in colon cancer cells. | Mutation research 20010510 |