Ns-398
| Title | Journal |
|---|---|
| Resveratrol induces sumoylated COX-2-dependent anti-proliferation in human prostate cancer LNCaP cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180201 |
| Leptin induces CREB-dependent aromatase activation through COX-2 expression in breast cancer cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170801 |
| Suppression of calpain expression by NSAIDs is associated with inhibition of cell migration in rat duodenum. | Toxicology 20170515 |
| Aryl hydrocarbon receptor-ligand axis mediates pulmonary fibroblast migration and differentiation through increased arachidonic acid metabolism. | Toxicology 20160831 |
| Mitophagy inhibits proliferation by decreasing cyclooxygenase-2 (COX-2) in arsenic trioxide-treated HepG2 cells. | Environmental toxicology and pharmacology 20160701 |
| Exposure to p,p'-DDE Alters Macrophage Reactivity and Increases Macrophage Numbers in Adipose Stromal Vascular Fraction. | Toxicological sciences : an official journal of the Society of Toxicology 20160301 |
| Lovastatin lactone elicits human lung cancer cell apoptosis via a COX-2/PPARγ-dependent pathway. | Oncotarget 20160301 |
| The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells. | PloS one 20160101 |
| Bisphenol A-induced epithelial to mesenchymal transition is mediated by cyclooxygenase-2 up-regulation in human endometrial carcinoma cells. | Reproductive toxicology (Elmsford, N.Y.) 20151201 |
| Hexachlorobenzene promotes angiogenesis in vivo, in a breast cancer model and neovasculogenesis in vitro, in the human microvascular endothelial cell line HMEC-1. | Toxicology letters 20151119 |
| The Effect of Cadmium on COX-1 and COX-2 Gene, Protein Expression, and Enzymatic Activity in THP-1 Macrophages. | Biological trace element research 20150101 |
| TCDD‑induced chick cardiotoxicity is abolished by a selective cyclooxygenase‑2 (COX‑2) inhibitor NS398. | Archives of toxicology 20140901 |
| Vascular endothelial growth factor-C modulates proliferation and chemoresistance in acute myeloid leukemic cells through an endothelin-1-dependent induction of cyclooxygenase-2. | Biochimica et biophysica acta 20140201 |
| Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib. | Journal of lipid research 20131101 |
| Mechanisms of ceramide-induced COX-2-dependent apoptosis in human ovarian cancer OVCAR-3 cells partially overlapped with resveratrol. | Journal of cellular biochemistry 20130801 |
| Reciprocal regulation of cyclooxygenase 2 and heme oxygenase 1 upon arsenic trioxide exposure in normal human lung fibroblast. | Journal of biochemical and molecular toxicology 20130601 |
| Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20130515 |
| COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells. | Molecular cancer therapeutics 20130101 |
| Involvement of hypothalamic cyclooxygenase-2, interleukin-1β and melanocortin in the development of docetaxel-induced anorexia in rats. | Toxicology 20121216 |
| Ahr2-dependence of PCB126 effects on the swim bladder in relation to expression of CYP1 and cox-2 genes in developing zebrafish. | Toxicology and applied pharmacology 20121201 |
| Melittin suppresses VEGF-A-induced tumor growth by blocking VEGFR-2 and the COX-2-mediated MAPK signaling pathway. | Journal of natural products 20121126 |
| Heat shock protein 27 expression in areca quid chewing-associated oral squamous cell carcinomas. | Oral diseases 20121001 |
| The dietary fatty acid 10E12Z-CLA induces epiregulin expression through COX-2 dependent PGF(2α) synthesis in adipocytes. | Prostaglandins & other lipid mediators 20121001 |
| Immunohistochemical and functional studies for M₃ muscarinic receptors and cyclo-oxygenase-2 expressed in the mouse atrium. | Autonomic & autacoid pharmacology 20121001 |
| Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner. | Experimental & molecular medicine 20120930 |
| Amelioration of cisplatin-induced rat renal lesions by a cyclooxygenase (COX)-2 selective inhibitor. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20120901 |
| Helicobacter pylori promotes apoptosis, activates cyclooxygenase (COX)-2 and inhibits heat shock protein HSP70 in gastric cancer epithelial cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120901 |
| Inhibition of cytosolic phospholipase A(2) alpha protects against focal ischemic brain damage in mice. | Brain research 20120830 |
| Expression of pleiotrophin, an important regulator of cell migration, is inhibited in intestinal epithelial cells by treatment with non-steroidal anti-inflammatory drugs. | Growth factors (Chur, Switzerland) 20120801 |
| Ellagic acid facilitates indomethacin-induced gastric ulcer healing via COX-2 up-regulation. | Acta biochimica et biophysica Sinica 20120701 |
| Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects. | Journal of cardiovascular pharmacology 20120601 |
| Hyperbaric oxygen preconditioning protects cortical neurons against oxygen-glucose deprivation injury: role of peroxisome proliferator-activated receptor-gamma. | Brain research 20120503 |
| Cyclooxygenase-2 contributes to VX-induced cell death in cultured cortical neurons. | Toxicology letters 20120405 |
| Prostaglandin E2 contributes to the synthesis of brain-derived neurotrophic factor in primary sensory neuron in ganglion explant cultures and in a neuropathic pain model. | Experimental neurology 20120401 |
| Combination of midazolam and a cyclooxygenase-2 inhibitor inhibits lipopolysaccharide-induced interleukin-6 production in human peripheral blood mononuclear cells. | Immunopharmacology and immunotoxicology 20120201 |
| Pyrrole alkanoic acid derivatives as nuisance inhibitors of microsomal prostaglandin E2 synthase-1. | European journal of medicinal chemistry 20120201 |
| Cyclooxygenase-2 inhibition causes antiangiogenic effects on tumor endothelial and vascular progenitor cells. | International journal of cancer 20120101 |
| Dual action of a selective cyclooxygenase-2 inhibitor on vascular endothelial growth factor expression in human hepatocellular carcinoma cells: novel involvement of discoidin domain receptor 2. | Journal of cancer research and clinical oncology 20120101 |
| Prophylactic and therapeutic benefits of COX-2 inhibitor on motility dysfunction in bowel obstruction: roles of PGE₂ and EP receptors. | American journal of physiology. Gastrointestinal and liver physiology 20120101 |
| NS398 induces apoptosis in non-small cell lung cancer cells. | Journal of cancer research and clinical oncology 20120101 |
| IL-6 production stimulated by CD14(+) monocytes-paracrined IL-1β does not contribute to the immunosuppressive activity of human umbilical cord mesenchymal stem cells. | Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 20120101 |
| Inhibition of NO(2), PGE(2), TNF-α, and iNOS EXpression by Shorea robusta L.: An Ethnomedicine Used for Anti-Inflammatory and Analgesic Activity. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Mechanism of P-glycoprotein expression in the SGC7901 human gastric adenocarcinoma cell line induced by cyclooxygenase-2. | Asian Pacific journal of cancer prevention : APJCP 20120101 |
| Arachidonic acid and its COX1/2 metabolites inhibit interferon-γ mediated induction of indoleamine-2,3 dioxygenase in THP-1 cells and human monocytes. | Prostaglandins, leukotrienes, and essential fatty acids 20120101 |
| Cyclooxygenase-2-derived prostacyclin protective role on endotoxin-induced mouse cardiomyocyte mortality. | Cardiovascular toxicology 20111201 |
| SO(2)-induced neurotoxicity is mediated by cyclooxygenases-2-derived prostaglandin E(2) and its downstream signaling pathway in rat hippocampal neurons. | Toxicological sciences : an official journal of the Society of Toxicology 20111201 |
| Lipopolysaccharide initiates a bypass feedback loop of epidermal growth factor receptor signaling by HPS70-induced COX-2 in H22 hepatocarcinoma cells. | Oncology reports 20111201 |
| COX-2 inhibitors block chemotherapeutic agent-induced apoptosis prior to commitment in hematopoietic cancer cells. | Biochemical pharmacology 20111115 |
| Effects of endotoxin and influence of cyclooxygenase-2 on β-adrenergic mediated relaxation in isolated equine digital artery. | Veterinary journal (London, England : 1997) 20111101 |
| Positive feedback loop between prostaglandin E2 and EGF-like factors is essential for sustainable activation of MAPK3/1 in cumulus cells during in vitro maturation of porcine cumulus oocyte complexes. | Biology of reproduction 20111101 |
| The structure of NS-398 bound to cyclooxygenase-2. | Journal of structural biology 20111101 |
| Tumor-associated macrophages mediate immunosuppression in the renal cancer microenvironment by activating the 15-lipoxygenase-2 pathway. | Cancer research 20111015 |
| Novel human mPGES-1 inhibitors identified through structure-based virtual screening. | Bioorganic & medicinal chemistry 20111015 |
| Activation of the receptor for advanced glycation end products (RAGE) exacerbates experimental autoimmune myasthenia gravis symptoms. | Clinical immunology (Orlando, Fla.) 20111001 |
| Aldosterone stimulates superoxide production in macula densa cells. | American journal of physiology. Renal physiology 20110901 |
| Role of prostaglandin E2 in the synthesis of the pro-inflammatory cytokine interleukin-6 in primary sensory neurons: an in vivo and in vitro study. | Journal of neurochemistry 20110901 |
| Evidence that PGE2 in the dorsal and median raphe nuclei is involved in LPS-induced anorexia in rats. | Pharmacology, biochemistry, and behavior 20110901 |
| Nonsteroidal anti-inflammatory treatment prevents delayed effects of early life stress in rats. | Biological psychiatry 20110901 |
| Cox-2 inhibitors induce early c-Myc downregulation and lead to expression of differentiation markers in leukemia cells. | Cell cycle (Georgetown, Tex.) 20110901 |
| Endogenous prostaglandin E2 inhibits aberrant overgrowth of rheumatoid synovial tissue and the development of osteoclast activity through EP4 receptor. | Arthritis and rheumatism 20110901 |
| Lignan derivatives from Krameria lappacea roots inhibit acute inflammation in vivo and pro-inflammatory mediators in vitro. | Journal of natural products 20110826 |
| Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro. | Bioorganic & medicinal chemistry 20110815 |
| Involvement of microRNAs in dioxin-induced liver damage in the mouse. | Toxicological sciences : an official journal of the Society of Toxicology 20110801 |
| Type 1 diabetes-induced hyper-responsiveness to 5-hydroxytryptamine in rat pulmonary arteries via oxidative stress and induction of cyclooxygenase-2. | The Journal of pharmacology and experimental therapeutics 20110701 |
| Oxidative stress mediates chemical hypoxia-induced injury and inflammation by activating NF-κb-COX-2 pathway in HaCaT cells. | Molecules and cells 20110630 |
| Functionality and specificity of gene markers for skin sensitization in dendritic cells. | Toxicology letters 20110610 |
| Enhanced proliferation, invasion, and epithelial-mesenchymal transition of nicotine-promoted gastric cancer by periostin. | World journal of gastroenterology 20110607 |
| Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death. | Neuropharmacology 20110601 |
| Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice. | Progress in neuro-psychopharmacology & biological psychiatry 20110601 |
| Low-volume binary drug therapy for the treatment of hypovolemia. | Shock (Augusta, Ga.) 20110601 |
| Tissue factor pathway inhibitor 2 is induced by thrombin in human macrophages. | Biochimica et biophysica acta 20110601 |
| High-throughput screen of protein expression levels induced by cyclooxygenase-2 during influenza a virus infection. | Clinica chimica acta; international journal of clinical chemistry 20110512 |
| The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20110501 |
| Antiviral activity of a selective COX-2 inhibitor NS-398 on avian influenza H5N1 infection. | Influenza and other respiratory viruses 20110501 |
| 5-Hydroxytryptamine induces cyclooxygenase-2 in rat vascular smooth muscle cells: Mechanisms involving Src, PKC and MAPK activation [corrected]. | European journal of pharmacology 20110410 |
| HT-29 colorectal cancer cells undergoing apoptosis overexpress COX-2 to delay ursolic acid-induced cell death. | Biochimie 20110401 |
| Roles of cyclooxygenase 2 in sevoflurane- and olprinone-induced early phase of preconditioning and postconditioning against myocardial infarction in rat hearts. | Journal of cardiovascular pharmacology and therapeutics 20110301 |
| Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes. | The Journal of general virology 20110301 |
| Vitamin C down-regulates VEGF production in B16F10 murine melanoma cells via the suppression of p42/44 MAPK activation. | Journal of cellular biochemistry 20110301 |
| Interleukin-6 and soluble interleukin-6 receptor suppress osteoclastic differentiation by inducing PGE(2) production in chondrocytes. | Journal of oral science 20110301 |
| A cyclooxygase-2 inhibitor NS-398-enhanced apoptosis of esophageal carcinoma cell EC9706 by adjusting expression of survivin and caspase-3. | Cancer investigation 20110201 |
| Reduced tumour progression and angiogenesis in 1,2-dimethylhydrazine mice treated with NS-398 is associated with down-regulation of cyclooxygenase-2 and decreased beta-catenin nuclear localisation. | Cell communication & adhesion 20110201 |
| Houttuynia cordata, a novel and selective COX-2 inhibitor with anti-inflammatory activity. | Journal of ethnopharmacology 20110127 |
| Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway. | The Journal of biological chemistry 20110121 |
| Transcript profiling identifies novel key players mediating the growth inhibitory effect of NS-398 on human pancreatic cancer cells. | European journal of pharmacology 20110110 |
| Cyclooxygenase-2 protects germ cells against spermatogenesis disturbance in experimental cryptorchidism model mice. | Journal of andrology 20110101 |
| Pathophysiology of motility dysfunction in bowel obstruction: role of stretch-induced COX-2. | American journal of physiology. Gastrointestinal and liver physiology 20110101 |
| Prevotella intermedia induces prostaglandin E2 via multiple signaling pathways. | Journal of dental research 20110101 |
| Inhibition of untransformed prostaglandin H(2) production and stretch-induced contraction of rabbit pulmonary arteries by indoxam, a selective secretory phospholipase A(2) inhibitor. | Journal of pharmacological sciences 20110101 |
| [Regulatory interconnections of cyclooxigenase and inducible no-synthase in urinary bladder epithelial cells of the frog Rana temporaria under action of bacterial stimuli]. | Zhurnal evoliutsionnoi biokhimii i fiziologii 20110101 |
| The neuroprotective effects of cyclooxygenase-2 inhibition in a mouse model of aneurysmal subarachnoid hemorrhage. | Acta neurochirurgica. Supplement 20110101 |
| Hydrogen sulfide protects against chemical hypoxia-induced cytotoxicity and inflammation in HaCaT cells through inhibition of ROS/NF-κB/COX-2 pathway. | PloS one 20110101 |
| Hypertonic stress induces VEGF production in human colon cancer cell line Caco-2: inhibitory role of autocrine PGE₂. | PloS one 20110101 |
| Intravenous anesthetic propofol suppresses prostaglandin E2 production in murine dendritic cells. | Journal of immunotoxicology 20110101 |
| Microparticles from patients with metabolic syndrome induce vascular hypo-reactivity via Fas/Fas-ligand pathway in mice. | PloS one 20110101 |
| The effect of the expression of angiotensin II on extracellular matrix metalloproteinase inducer (EMMPRIN) in macrophages is mediated via the AT1/COX-2/PGE2 pathway. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20101201 |
| Prostaglandin F2α (PGF2α) stimulates PTGS2 expression and PGF2α synthesis through NFKB activation via reactive oxygen species in the corpus luteum of pseudopregnant rats. | Reproduction (Cambridge, England) 20101201 |
| Non-steroidal anti-inflammatory drugs inhibit calpain activity and membrane localization of calpain 2 protease. | The international journal of biochemistry & cell biology 20101201 |
| Enhanced cyclooxygenase 2-mediated vasorelaxation in coronary arteries from insulin-resistant obese Zucker rats. | Atherosclerosis 20101201 |
| [Application of non-steroidal anti-inflammatory drugs to enhance 5-fluorouracil efficacy in experimental systems]. | Magyar onkologia 20101201 |
| [Nonsteroidal anti-inflammatory drug NS398 induces RECK expression in the animal model of prostate cancer]. | Zhonghua nan ke xue = National journal of andrology 20101201 |
| Suppression of migratory/invasive ability and induction of apoptosis in adenomyosis-derived mesenchymal stem cells by cyclooxygenase-2 inhibitors. | Fertility and sterility 20101101 |
| Chronic treatment with the cannabinoid 1 antagonist rimonabant altered vasoactive cyclo-oxygenase-derived products on arteries from obese Zucker rats. | Journal of cardiovascular pharmacology 20101101 |
| TCDD induced pericardial edema and relative COX-2 expression in medaka (Oryzias Latipes) embryos. | Toxicological sciences : an official journal of the Society of Toxicology 20101101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| NS-398 (a selective cyclooxygenase-2 inhibitor) decreases agonist-induced contraction of the human ureter via calcium channel inhibition. | Journal of endourology 20101101 |
| Contribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase-2 inhibitor, NS-398, on endotoxin-induced hypotension in rats. | Basic & clinical pharmacology & toxicology 20101101 |
| The role of cyclooxygenase-2-dependent signaling via cyclic AMP response element activation on aromatase up-regulation by o,p'-DDT in human breast cancer cells. | Toxicology letters 20101020 |
| Pro-inflammatory effects of commercial alpha-lactalbumin on RAW 264.7 macrophages is due to endotoxin contamination. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20101001 |
| Synthesis, anti-inflammatory activity, and in vitro antitumor effect of a novel class of cyclooxygenase inhibitors: 4-(aryloyl)phenyl methyl sulfones. | Journal of medicinal chemistry 20100923 |
| Modulation of the cyclooxygenase pathway via inhibition of nitric oxide production contributes to the anti-inflammatory activity of kaempferol. | European journal of pharmacology 20100910 |
| Brain cyclooxygenase-2 mediates interleukin-1-induced cellular activation in preoptic and arcuate hypothalamus, but not sickness symptoms. | Neurobiology of disease 20100901 |
| The apolipoprotein A-I mimetic peptide 4F prevents defects in vascular function in endotoxemic rats. | Journal of lipid research 20100901 |
| Celecoxib increases retinoid sensitivity in human colon cancer cell lines. | Cellular & molecular biology letters 20100901 |
| Nitric oxide regulates stretch-induced proliferation in C2C12 myoblasts. | Journal of muscle research and cell motility 20100901 |
| Inducible cyclooxygenase released prostaglandin E2 modulates the severity of infection caused by Streptococcus pyogenes. | Journal of immunology (Baltimore, Md. : 1950) 20100815 |
| Human beta-defensin-3 up-regulates cyclooxygenase-2 expression and prostaglandin E2 synthesis in human gingival fibroblasts. | Journal of periodontal research 20100801 |
| Chronic inhibition of nitric-oxide synthase potentiates endothelium-dependent contractions in the rat aorta by augmenting the expression of cyclooxygenase-2. | The Journal of pharmacology and experimental therapeutics 20100801 |
| Cyclooxygenase-2 inhibitor NS398 enhances radiosensitivity of radioresistant esophageal cancer cells by inhibiting AKT activation and inducing apoptosis. | Cancer investigation 20100801 |
| [Effect of COX-2 inhibitor on the expression of BCL-3 and cyclin D1 in human colon cancer cell line SW480]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20100801 |
| Triterpene saponins from Clematis chinensis and their potential anti-inflammatory activity. | Journal of natural products 20100723 |
| 1,5-Diarylimidazoles with strong inhibitory activity against COX-2 catalyzed PGE2 production from LPS-induced RAW 264.7 cells. | Bioorganic & medicinal chemistry letters 20100715 |
| Enhanced 5-fluorouracil cytotoxicity in high cyclooxygenase-2 expressing colorectal cancer cells and xenografts induced by non-steroidal anti-inflammatory drugs via downregulation of dihydropyrimidine dehydrogenase. | Cancer chemotherapy and pharmacology 20100701 |
| Wogonin inhibits osteoclast formation induced by lipopolysaccharide. | Phytotherapy research : PTR 20100701 |
| Lipopolysaccharide induces calcitonin gene-related peptide in the RAW264.7 macrophage cell line. | Immunology 20100701 |
| Pravastatin attenuates carboplatin-induced nephrotoxicity in rodents via peroxisome proliferator-activated receptor alpha-regulated heme oxygenase-1. | Molecular pharmacology 20100701 |
| Deceleration of regenerative response improves the outcome of rat with massive hepatectomy. | American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 20100701 |
| Cyclooxygenase-2 preserves flow-mediated remodelling in old obese Zucker rat mesenteric arteries. | Cardiovascular research 20100601 |
| Synthesis and cyclooxygenase inhibitory activities of some N-acylhydrazone derivatives of isoxazolo[4,5-d]pyridazin-4(5H)-ones. | European journal of medicinal chemistry 20100601 |
| Prostaglandin-E2 is produced by adult human epidermal melanocytes in response to UVB in a melanogenesis-independent manner. | Pigment cell & melanoma research 20100601 |
| Paradoxical thrombotic effects of aspirin: experimental study on 1000 animals. | Cardiovascular & hematological disorders drug targets 20100601 |
| Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production. | Journal of immunology (Baltimore, Md. : 1950) 20100601 |
| Statins inhibit cyclooxygenase-2 and matrix metalloproteinase-9 in human endothelial cells: anti-angiogenic actions possibly contributing to plaque stability. | Cardiovascular research 20100501 |
| PPARgamma agonists inhibit angiogenesis by suppressing PKCalpha- and CREB-mediated COX-2 expression in the human endothelium. | Cardiovascular research 20100501 |
| The role of TNF-alpha signaling pathway on COX-2 upregulation and cognitive decline induced by beta-amyloid peptide. | Behavioural brain research 20100501 |
| MnSOD protects against COX1-mediated endothelial dysfunction in chronic heart failure. | American journal of physiology. Heart and circulatory physiology 20100501 |
| Cyclooxygenase-2 and 5-lipoxygenase pathways in diosgenin-induced apoptosis in HT-29 and HCT-116 colon cancer cells. | International journal of oncology 20100501 |
| TGF-beta1 reverses inhibition of COX-2 with NS398 and increases invasion in prostate cancer cells. | The American journal of the medical sciences 20100501 |
| Stimulatory effects of areca nut extracts on prostaglandin E2 production by human polymorphonuclear leukocytes. | Journal of periodontology 20100501 |
| Prostaglandin E2 induces CYP1B1 expression via ligand-independent activation of the ERalpha pathway in human breast cancer cells. | Toxicological sciences : an official journal of the Society of Toxicology 20100401 |
| Derivatives of schisandrin with increased inhibitory potential on prostaglandin E(2) and leukotriene B(4) formation in vitro. | Bioorganic & medicinal chemistry 20100401 |
| Increased COX2 in the trigeminal nucleus caudalis is involved in orofacial pain induced by experimental tooth movement. | Anatomical record (Hoboken, N.J. : 2007) 20100301 |
| Hyaluronan inhibits prostaglandin E2 production via CD44 in U937 human macrophages. | The Tohoku journal of experimental medicine 20100301 |
| Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor. | British journal of cancer 20100216 |
| COX-2 inhibition controls P-glycoprotein expression and promotes brain delivery of phenytoin in chronic epileptic rats. | Neuropharmacology 20100201 |
| Cyclooxygenase-2 inhibition provides lasting protection against neonatal hypoxic-ischemic brain injury. | Critical care medicine 20100201 |
| Pharmacophore modeling and virtual screening for designing potential 5-lipoxygenase inhibitors. | Bioorganic & medicinal chemistry letters 20100201 |
| COX2 inhibitors for acquired brain injuries: is the time ripe? | Critical care medicine 20100201 |
| The role of cyclooxygenase (COX)-2 derived prostanoids on vasoconstrictor responses to phenylephrine is increased by exposure to low mercury concentration. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20100201 |
| Cyclooxygenase-2 inhibition inhibits PI3K/AKT kinase activity in epithelial ovarian cancer. | International journal of cancer 20100115 |
| Synthesis and PGE(2) production inhibition of 1H-furan-2,5-dione and 1H-pyrrole-2,5-dione derivatives. | Bioorganic & medicinal chemistry letters 20100115 |
| Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production. | Bioorganic & medicinal chemistry 20100115 |
| Lipopolysaccharide promoted proliferation and invasion of endometriotic stromal cells via induction of cyclooxygenase-2 expression. | Fertility and sterility 20100101 |
| Contribution of reactive oxygen species to migration/invasion of human glioblastoma cells U87 via ERK-dependent COX-2/PGE(2) activation. | Neurobiology of disease 20100101 |
| The influence of constitutive COX-2 in smooth muscle tissue on the contractile effect of phenylephrine in the rat abdominal aorta. | Frontiers in bioscience (Elite edition) 20100101 |
| Inhibition of cyclooxygenase-2 impairs the expression of essential plasma cell transcription factors and human B-lymphocyte differentiation. | Immunology 20100101 |
| Aspirin therapy: an attempt to explain the events of prothrombotic complications after treatment discontinuation. | Thrombosis and haemostasis 20100101 |
| Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts. | Biological & pharmaceutical bulletin 20100101 |
| Targeting the tumor microenvironment using photodynamic therapy combined with inhibitors of cyclooxygenase-2 or vascular endothelial growth factor. | Methods in molecular biology (Clifton, N.J.) 20100101 |
| Amyloid-β induces cyclooxygenase-2 and PGE2 release in human astrocytes in NF-κ B dependent manner. | Journal of Alzheimer's disease : JAD 20100101 |
| Role of prostanoid production and receptors in the regulation of retinal endogenous amino acid neurotransmitters by 8-isoprostaglandin E2, ex vivo. | Neurochemical research 20091201 |
| The effect of linolenic Acid on bovine oocyte maturation and development. | Biology of reproduction 20091201 |
| Aspirin induces apoptosis in mesenchymal stem cells requiring Wnt/beta-catenin pathway. | Cell proliferation 20091201 |
| Both B1R and B2R act as intermediate signaling molecules in high glucose-induced stimulation of glutamate uptake in ARPE cells. | Journal of cellular physiology 20091201 |
| Contribution of the prostaglandin E2/E-prostanoid 2 receptor signaling pathway in abscess formation in rat zymosan-induced pleurisy. | The Journal of pharmacology and experimental therapeutics 20091201 |
| Involvement of cyclooxygenase-2 in carbachol-induced positive inotropic response in mouse isolated left atrium. | The Journal of pharmacology and experimental therapeutics 20091201 |
| Multifunctional role of VIP in prostate cancer progression in a xenograft model: suppression by curcumin and COX-2 inhibitor NS-398. | Peptides 20091201 |
| Roles of a prostaglandin E-type receptor, EP3, in upregulation of matrix metalloproteinase-9 and vascular endothelial growth factor during enhancement of tumor metastasis. | Cancer science 20091201 |
| Possible involvement of microglia containing cyclooxygenase-1 in the accumulation of gonadotrophin-releasing hormone in the preoptic area in female rats. | Journal of neuroendocrinology 20091201 |
| Glucose promotes the production of interleukine-1beta and cyclooxygenase-2 in mesangial cells via enhanced (Pro)renin receptor expression. | Endocrinology 20091201 |
| [Celecoxib increased cellular ATRA sensitivity of human colon cancer cell lines through COX-2-independent mechanisms]. | Yao xue xue bao = Acta pharmaceutica Sinica 20091201 |
| Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in rats. | Gut 20091101 |
| Ovariectomy increases the formation of prostanoids and modulates their role in acetylcholine-induced relaxation and nitric oxide release in the rat aorta. | Cardiovascular research 20091101 |
| Nicotine enhances skin necrosis and expression of inflammatory mediators in a rat pressure ulcer model. | The British journal of dermatology 20091101 |
| COX-2 inhibition improves immune system homeostasis and decreases liver damage in septic rats. | The Journal of surgical research 20091101 |
| Prothrombotic and hemorrhagic effects of aspirin. | Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis 20091001 |
| Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs. | Molecular carcinogenesis 20091001 |
| Role of IL-1 beta and COX2 in silica-induced IL-6 release and loss of pneumocytes in co-cultures. | Toxicology in vitro : an international journal published in association with BIBRA 20091001 |
| Enhancement of 5-fluorouracil efficacy on high COX-2 expressing HCA-7 cells by low dose indomethacin and NS-398 but not on low COX-2 expressing HT-29 cells. | Pathology oncology research : POR 20090901 |
| Effect of cyclooxygenase-2 on the regulation of cerebral blood flow during neuronal activation in the rat. | Neuroscience research 20090901 |
| Cyclooxygenase-2 prevents fas-induced liver injury through up-regulation of epidermal growth factor receptor. | Hepatology (Baltimore, Md.) 20090901 |
| Cyclo-oxygenase-2 mediates hyperbaric oxygen preconditioning-induced neuroprotection in the mouse model of surgical brain injury. | Stroke 20090901 |
| Phenolic glycosides from Alangium salviifolium leaves with inhibitory activity on LPS-induced NO, PGE(2), and TNF-alpha production. | Bioorganic & medicinal chemistry letters 20090801 |
| Co-inhibition of cyclooxygenase-2 and dihydropyrimidine dehydrogenase by non-steroidal anti-inflammatory drugs in tumor cells and xenografts. | Anticancer research 20090801 |
| Omega-3 Fatty acids and inflammation: novel interactions reveal a new step in neutrophil recruitment. | PLoS biology 20090801 |
| 15-hydroxyprostaglandin dehydrogenase is down-regulated in gastric cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090715 |
| Effects of global or targeted deletion of the EP4 receptor on the response of osteoblasts to prostaglandin in vitro and on bone histomorphometry in aged mice. | Bone 20090701 |
| Heme-oxygenase-1 induction and carbon monoxide-releasing molecule inhibit lipopolysaccharide (LPS)-induced high-mobility group box 1 release in vitro and improve survival of mice in LPS- and cecal ligation and puncture-induced sepsis model in vivo. | Molecular pharmacology 20090701 |
| Design and synthesis of ten biphenyl-neolignan derivatives and their in vitro inhibitory potency against cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4-formation. | Bioorganic & medicinal chemistry 20090701 |
| MSCs inhibit monocyte-derived DC maturation and function by selectively interfering with the generation of immature DCs: central role of MSC-derived prostaglandin E2. | Blood 20090625 |
| Enhancement of doxorubicin cytotoxicity on human esophageal squamous cell carcinoma cells by indomethacin and 4-[5-(4-chlorophenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulfonamide (SC236) via inhibiting P-glycoprotein activity. | Molecular pharmacology 20090601 |
| Pyrazolo[3,4-d]pyrimidine derivatives as COX-2 selective inhibitors: synthesis and molecular modelling studies. | Archiv der Pharmazie 20090601 |
| Sex-dependent effect of cyclooxygenase-2 inhibition on mouse spatial memory. | Behavioural brain research 20090516 |
| Cyclooxygenase-2 in mucosal DC mediates induction of regulatory T cells in the intestine through suppression of IL-4. | Mucosal immunology 20090501 |
| Helium-induced late preconditioning in the rat heart in vivo. | British journal of anaesthesia 20090501 |
| [The role and mechanisms of cyclooxygenase-2 inhibitors on the proliferation of hepatic stellate cell]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090501 |
| Discovering chemical modifiers of oncogene-regulated hematopoietic differentiation. | Nature chemical biology 20090401 |
| COX-2 inhibitor reduces skeletal muscle hypertrophy in mice. | American journal of physiology. Regulatory, integrative and comparative physiology 20090401 |
| Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition. | Neuropharmacology 20090401 |
| Proteomics reveals protein profile changes in cyclooxygenase-2 inhibitor-treated endometrial cancer cells. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20090401 |
| Inhibition of COX-2 and activation of peroxisome proliferator-activated receptor gamma synergistically inhibits proliferation and induces apoptosis of human pancreatic carcinoma cells. | Cancer letters 20090318 |
| Inhibitory activity of prostaglandin E2 production by the synthetic 2'-hydroxychalcone analogues: Synthesis and SAR study. | Bioorganic & medicinal chemistry letters 20090315 |
| Involvement of PGE2 and PGDH but not COX-2 in thrombin-induced cortical neuron apoptosis. | Neuroscience letters 20090313 |
| Induction of prostacyclin by steady laminar shear stress suppresses tumor necrosis factor-alpha biosynthesis via heme oxygenase-1 in human endothelial cells. | Circulation research 20090227 |
| Selective inhibition of cyclooxygenase-2 attenuates nitroglycerin-induced calmodulin-dependent protein kinase II alpha in rat trigeminal nucleus caudalis. | Neuroscience letters 20090220 |
| Endothelial dysfunction in mice with streptozotocin-induced type 1 diabetes is opposed by compensatory overexpression of cyclooxygenase-2 in the vasculature. | Endocrinology 20090201 |
| Effects of nicotine and lipopolysaccharide on the expression of matrix metalloproteinases, plasminogen activators, and their inhibitors in human osteoblasts. | Archives of oral biology 20090201 |
| R(+)-methanandamide-induced apoptosis of human cervical carcinoma cells involves a cyclooxygenase-2-dependent pathway. | Pharmaceutical research 20090201 |
| Reactive oxygen species regulate properties of transformation in UROtsa cells exposed to monomethylarsonous acid by modulating MAPK signaling. | Toxicology 20090108 |
| Altered hippocampal long-term synaptic plasticity in mice deficient in the PGE2 EP2 receptor. | Journal of neurochemistry 20090101 |
| Synthesis of biflavones having a 6-O-7'' linkage and effects on cyclooxygenase-2 and inducible nitric oxide synthase. | Bioorganic & medicinal chemistry letters 20090101 |
| Terameprocol, a methylated derivative of nordihydroguaiaretic acid, inhibits production of prostaglandins and several key inflammatory cytokines and chemokines. | Journal of inflammation (London, England) 20090101 |
| NS-398, ibuprofen, and cyclooxygenase-2 RNA interference produce significantly different gene expression profiles in prostate cancer cells. | Molecular cancer therapeutics 20090101 |
| p38 MAPK contributes to angiotensin II-induced COX-2 expression in aortic fibroblasts from normotensive and hypertensive rats. | Journal of hypertension 20090101 |
| NS-398 induces apoptosis in human esophageal cancer cells through inhibition of NF-kappaB downstream regulation of cyclooxygenase-2. | Cancer investigation 20090101 |
| In vitro anti-inflammatory activity of carvacrol: Inhibitory effect on COX-2 catalyzed prostaglandin E(2) biosynthesis. | Archives of pharmacal research 20090101 |
| NS398 protects cells from sodium nitroprusside-mediated cytotoxicity through enhancing HO-1 induction independent of COX-2 inhibition. | Archives of pharmacal research 20090101 |
| Microglial inhibition of neuroprotection by antagonists of the EP1 prostaglandin E2 receptor. | Journal of neuroinflammation 20090101 |
| Identification of novel cyclooxygenase-2-dependent genes in Helicobacter pylori infection in vivo. | Molecular cancer 20090101 |
| Chronic COX inhibition reduces diabetes-induced hyperfiltration, proteinuria, and renal pathological markers in 36-week B6-Ins2(Akita) mice. | American journal of nephrology 20090101 |
| Cyclo-oxygenase 2 modulates chemoresistance in breast cancer cells involving NF-kappaB. | Cellular oncology : the official journal of the International Society for Cellular Oncology 20090101 |
| Smooth muscle cell arachidonic acid release, migration, and proliferation are markedly attenuated in mice null for calcium-independent phospholipase A2beta. | The Journal of biological chemistry 20081205 |
| Phosphorylation of TRPV1 by neurokinin-1 receptor agonist exaggerates the capsaicin-mediated substance P release from cultured rat dorsal root ganglion neurons. | Neuropharmacology 20081201 |
| Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner. | Mechanisms of ageing and development 20081201 |
| Xenon induces late cardiac preconditioning in vivo: a role for cyclooxygenase 2? | Anesthesia and analgesia 20081201 |
| Atheroprotective effects of methotrexate on reverse cholesterol transport proteins and foam cell transformation in human THP-1 monocyte/macrophages. | Arthritis and rheumatism 20081201 |
| NS-398, a selective COX-2 inhibitor, inhibits proliferation of IL-1beta-stimulated vascular smooth muscle cells by induction of HO-1. | Biochemical and biophysical research communications 20081128 |
| Determination of prostaglandin E(2) by on-line solid-phase extraction-liquid chromatography with ultraviolet detection for microsomal prostaglandin E(2) synthase-1 inhibitor screening. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20081115 |
| Curcumin inhibits VEGF-mediated angiogenesis in human intestinal microvascular endothelial cells through COX-2 and MAPK inhibition. | Gut 20081101 |
| Role of cyclooxygenase isoforms in prostacyclin biosynthesis and murine prehepatic portal hypertension. | American journal of physiology. Gastrointestinal and liver physiology 20081101 |
| Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats. | Journal of Zhejiang University. Science. B 20081101 |
| Heterotypic contact reveals a COX-2-mediated suppression of osteoblast differentiation by endothelial cells: A negative modulatory role for prostanoids in VEGF-mediated cell: cell communication? | Experimental cell research 20081015 |
| Prevention of both direct and cross-priming of antitumor CD8+ T-cell responses following overproduction of prostaglandin E2 by tumor cells in vivo. | Cancer research 20080915 |
| Cyclooxygenases 1 and 2 contribute to peroxynitrite-mediated inflammatory pain hypersensitivity. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080901 |
| VEGF expression and the effect of NSAIDs on ascites cell proliferation in the hen model of ovarian cancer. | Gynecologic oncology 20080901 |
| Induction of apoptosis and cell cycle arrest by NS398 in oral squamous cell carcinoma cells via downregulation of E2 promoter-binding factor-1. | Oncology reports 20080901 |
| [Anti-tumor mechanisms and regulation of survivin by selective cyclooxygenase-2 inhibitor]. | The Korean journal of hepatology 20080901 |
| [Down-regulation of survivin in growth inhibition of hepatoma cells induced by a selective cyclooxygenase-2 inhibitor]. | The Korean journal of hepatology 20080901 |
| Brain neuronal/inducible nitric oxide synthases and cyclooxygenase-1 are involved in the bombesin-induced activation of central adrenomedullary outflow in rats. | European journal of pharmacology 20080820 |
| Resveratrol causes COX-2- and p53-dependent apoptosis in head and neck squamous cell cancer cells. | Journal of cellular biochemistry 20080815 |
| The COX-2 selective inhibitor-independent COX-2 effect on colon carcinoma cells is associated with the Delta1/Notch1 pathway. | Digestive diseases and sciences 20080801 |
| Anti-apoptotic roles of prostaglandin E2 and F2alpha in bovine luteal steroidogenic cells. | Biology of reproduction 20080801 |
| Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity. | Journal of medicinal chemistry 20080724 |
| A new prostate cancer therapeutic approach: combination of androgen ablation with COX-2 inhibitor. | International journal of cancer 20080701 |
| Cyclooxygenase-dependent vasoconstricting factor(s) in remodelled rat femoral arteries. | Cardiovascular research 20080701 |
| Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells. | Oncology reports 20080701 |
| Non-steroidal anti-inflammatory drugs suppress the ERK signaling pathway via block of Ras/c-Raf interaction and activation of MAP kinase phosphatases. | Cellular signalling 20080601 |
| Radiosensitization of melanoma cells through combined inhibition of protein regulators of cell survival. | Apoptosis : an international journal on programmed cell death 20080601 |
| Expression of cyclooxygenase genes and production of prostaglandins during ovulation in the ovarian follicles of Xenopus laevis. | General and comparative endocrinology 20080601 |
| Selective inhibition of cyclooxygenase-2 suppresses the growth of pancreatic cancer cells in vitro and in vivo. | The Tohoku journal of experimental medicine 20080601 |
| Nickel alterations of TLR2-dependent chemokine profiles in lung fibroblasts are mediated by COX-2. | American journal of respiratory cell and molecular biology 20080501 |
| Drug-induced alterations to gene and protein expression in intestinal epithelial cell 6 cells suggest a role for calpains in the gastrointestinal toxicity of nonsteroidal anti-inflammatory agents. | The Journal of pharmacology and experimental therapeutics 20080501 |
| Mechanism of growth inhibitory effects of cyclooxygenase-2 inhibitor-NS398 on cancer cells. | Cancer investigation 20080501 |
| [The radiosensitization effect of cyclooxygenase-2 selective inhibitor NS-398 on HepG2 cells and its mechanism]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20080501 |
| Butyrate and trichostatin A attenuate nuclear factor kappaB activation and tumor necrosis factor alpha secretion and increase prostaglandin E2 secretion in human peripheral blood mononuclear cells. | Nutrition research (New York, N.Y.) 20080501 |
| Neuronal effects of 4-t-Butylcatechol: a model for catechol-containing antioxidants. | Toxicology and applied pharmacology 20080415 |
| Inhibition of cyclooxygenase-2 aggravates secretory phospholipase A2-mediated progression of acute liver injury. | Toxicology and applied pharmacology 20080415 |
| Oxidized low density lipoprotein activates peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma through MAPK-dependent COX-2 expression in macrophages. | The Journal of biological chemistry 20080411 |
| The cyclooxygenase-2/prostaglandin E2 pathway is involved in the somatostatin-induced decrease of epileptiform bursting in the mouse hippocampus. | Neuropharmacology 20080401 |
| The nonsteroidal anti-inflammatory drug NS398 reactivates SPARC expression via promoter demethylation to attenuate invasiveness of lung cancer cells. | Experimental biology and medicine (Maywood, N.J.) 20080401 |
| Statins inhibit proliferation and induce apoptosis in Barrett's esophageal adenocarcinoma cells. | The American journal of gastroenterology 20080401 |
| [Nonsteroidal anti-inflammatory drug NS398 regulates the RECK gene expression in the prostate carcinoma strain DU145]. | Zhonghua nan ke xue = National journal of andrology 20080401 |
| [Effect of NS-398 on cyclooxygenase-2 expression and proliferation of HepG2 cells]. | Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20080401 |
| Novel sulfonanilide analogs decrease aromatase activity in breast cancer cells: synthesis, biological evaluation, and ligand-based pharmacophore identification. | Journal of medicinal chemistry 20080313 |
| Resveratrol sensitizes melanomas to TRAIL through modulation of antiapoptotic gene expression. | Experimental cell research 20080310 |
| Selective COX-2 inhibitors. Part 2: synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides. | Bioorganic & medicinal chemistry 20080301 |
| Cyclooxygenase-2 inhibition prevents migration of colorectal cancer cells to extracellular matrix by down-regulation of matrix metalloproteinase-2 expression. | Diseases of the colon and rectum 20080301 |
| Nuclear factor-kappaB activation and postischemic inflammation are suppressed in CD36-null mice after middle cerebral artery occlusion. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080213 |
| CHOP transcription factor mediates IL-8 signaling in cystic fibrosis bronchial epithelial cells. | American journal of respiratory cell and molecular biology 20080201 |
| Cannabinoids stimulate prostaglandin production by human gestational tissues through a tissue- and CB1-receptor-specific mechanism. | American journal of physiology. Endocrinology and metabolism 20080201 |
| Differential effects of selective cyclooxygenase-2 inhibitors in inhibiting proliferation and induction of apoptosis in oral squamous cell carcinoma. | Oncology reports 20080201 |
| Cyclooxygenase-1 suppresses lipopolysaccharide-induced changes in rat gastric inducible nitric oxide synthase. | Critical care medicine 20080201 |
| Induction of prostaglandin E2 synthesis and microsomal prostaglandin E synthase-1 expression in murine microglia by glioma-derived soluble factors. Laboratory investigation. | Journal of neurosurgery 20080201 |
| Sensitization of meningeal nociceptors: inhibition by naproxen. | The European journal of neuroscience 20080201 |
| Cyclooxygenase-2 induction by lysophosphatidylcholine in cultured rat vascular smooth muscle cells: involvement of the p38MAPK pathway. | Biomedical research (Tokyo, Japan) 20080201 |
| Evidence that PAR2-triggered prostaglandin E2 (PGE2) formation involves the ERK-cytosolic phospholipase A2-COX-1-microsomal PGE synthase-1 cascade in human lung epithelial cells. | Cell biochemistry and function 20080101 |
| Resveratrol is pro-apoptotic and thyroid hormone is anti-apoptotic in glioma cells: both actions are integrin and ERK mediated. | Carcinogenesis 20080101 |
| Suppression of aromatase in human breast cells by a cyclooxygenase-2 inhibitor and its analog involves multiple mechanisms independent of cyclooxygenase-2 inhibition. | Steroids 20080101 |
| NS-398 enhances the efficacy of gemcitabine against lung adenocarcinoma through up-regulation of p21WAF1 and p27KIP1 protein. | Neoplasma 20080101 |
| Activation of interleukin-32 pro-inflammatory pathway in response to influenza A virus infection. | PloS one 20080101 |
| Cyclooxygenase-2-derived endogenous prostacyclin reduces apoptosis and enhances embryo viability in mouse. | Prostaglandins, leukotrienes, and essential fatty acids 20080101 |
| Selective cyclooxygenase-2 inhibition suppresses basic fibroblast growth factor expression in human esophageal adenocarcinoma. | Molecular carcinogenesis 20071201 |
| Aristolochic Acid induces heart failure in zebrafish embryos that is mediated by inflammation. | Toxicological sciences : an official journal of the Society of Toxicology 20071201 |
| Role of prostaglandins in collecting duct-derived endothelin-1 regulation of blood pressure and water excretion. | American journal of physiology. Renal physiology 20071201 |
| Involvement of COX-1 in A3 adenosine receptor-mediated contraction through endothelium in mice aorta. | American journal of physiology. Heart and circulatory physiology 20071201 |
| Cyclooxygenase-2 inhibitors prevent the development of chemoresistance phenotype in a breast cancer cell line by inhibiting glycoprotein p-170 expression. | Endocrine-related cancer 20071201 |
| Hypoxia-inducible factor 1alpha is involved in the prostaglandin metabolism of osteoarthritic cartilage through up-regulation of microsomal prostaglandin E synthase 1 in articular chondrocytes. | Arthritis and rheumatism 20071201 |
| Effects of cyclooxygenase (COX) inhibition on memory impairment and hippocampal damage in the early period of cerebral hypoperfusion in rats. | European journal of pharmacology 20071121 |
| Pathogenesis of aryl hydrocarbon receptor-mediated development of lymphoma is associated with increased cyclooxygenase-2 expression. | The American journal of pathology 20071101 |
| Microparticles stimulate the synthesis of prostaglandin E(2) via induction of cyclooxygenase 2 and microsomal prostaglandin E synthase 1. | Arthritis and rheumatism 20071101 |
| Effect of etidronate on COX-2 expression and PGE(2) production in macrophage-like RAW 264.7 cells stimulated by titanium particles. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20071101 |
| Inhibition of cyclooxygenase-2 down-regulates osteoclast and osteoblast differentiation and favours adipocyte formation in vitro. | European journal of pharmacology 20071031 |
| Cyclooxygenase-2 inhibitors demonstrate anti-proliferative effects in oesophageal cancer cells by prostaglandin E(2)-independent mechanisms. | Cancer letters 20071028 |
| The role of cyclooxygenase-2/prostanoid pathway in visceral pain induced liver stress response in rats. | Chinese medical journal 20071020 |
| Modifications produced by selective inhibitors of cyclooxygenase and ultra low dose aspirin on platelet activity in portal hypertension. | World journal of gastroenterology 20071014 |
| Involvement of cyclooxygenase-2 in the tumor site-dependent production of parathyroid hormone-related protein in colon 26 carcinoma. | Cancer science 20071001 |
| COX-2-dependent and potentially cardioprotective effects of negative inotropic substances released after ischemia. | American journal of physiology. Heart and circulatory physiology 20071001 |
| Radiosensitization of human glioma cells by cyclooxygenase-2 (COX-2) inhibition: independent on COX-2 expression and dependent on the COX-2 inhibitor and sequence of administration. | International journal of radiation biology 20071001 |
| Inhibition of COX-2 with NS-398 decreases colon cancer cell motility through blocking epidermal growth factor receptor transactivation: possibilities for combination therapy. | Cell proliferation 20071001 |
| Live imaging of chronic inflammation caused by mutation of zebrafish Hai1. | Journal of cell science 20071001 |
| Selective COX-2 inhibition markedly slows disease progression and attenuates altered prostanoid production in Han:SPRD-cy rats with inherited kidney disease. | American journal of physiology. Renal physiology 20070901 |
| Dexamethasone decreases contraction to electrical field stimulation in mesenteric arteries from spontaneously hypertensive rats through decreases in thromboxane A2 release. | The Journal of pharmacology and experimental therapeutics 20070901 |
| Effect of acetaminophen, a cyclooxygenase inhibitor, on Morris water maze task performance in mice. | Journal of psychopharmacology (Oxford, England) 20070901 |
| The effects of combining docetaxel and cyclooxygenase-2 inhibitors on proliferation and apoptosis in epithelial ovarian cancer. | Anti-cancer drugs 20070901 |
| Akt-dependent heme oxygenase-1 induction by NS-398 in C6 glial cells: a potential role for CO in prevention of oxidative damage from hypoxia. | Neuropharmacology 20070901 |
| Effects of celecoxib on voltage-gated calcium channel currents in rat pheochromocytoma (PC12) cells. | Pharmacological research 20070901 |
| Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells. | Experimental & molecular medicine 20070831 |
| Normal or stress-induced fibroblast senescence involves COX-2 activity. | Experimental cell research 20070815 |
| Abnormalities of prostaglandins and cyclooxygenase enzymes in female patients with slow-transit constipation. | Gastroenterology 20070801 |
| Long-term fenofibrate treatment impairs endothelium-dependent dilation to acetylcholine by altering the cyclooxygenase pathway. | Cardiovascular research 20070715 |
| Bradykinin-induced nociceptor sensitisation to heat depends on cox-1 and cox-2 in isolated rat skin. | Pain 20070701 |
| Strontium ranelate promotes osteoblastic differentiation and mineralization of murine bone marrow stromal cells: involvement of prostaglandins. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070701 |
| Thrombin inhibits migration of human hepatic myofibroblasts. | American journal of physiology. Gastrointestinal and liver physiology 20070701 |
| Involvement of inducible nitric oxide synthase in blood flow decrease in vein induced by hen-egg white lysozyme. | Biological & pharmaceutical bulletin 20070701 |
| Depolarization and decreased surface expression of K+ channels contribute to NSAID-inhibition of intestinal restitution. | Biochemical pharmacology 20070630 |
| Anti-EGFR and ErbB-2 antibodies attenuate cyclooxygenase-2 expression and cooperatively inhibit survival of human colon cancer cells. | Cancer letters 20070628 |
| Regulation of COX-2 mediates acid-induced bone calcium efflux in vitro. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20070601 |
| Cyclooxygenase-2 inhibitor reduces simvastatin-induced bone morphogenetic protein-2 and bone formation in vivo. | Journal of periodontal research 20070601 |
| Cyclooxygenase-1 inhibition delays recovery of the cutaneous barrier disruption caused by mechanical scratching in mice. | The British journal of dermatology 20070601 |
| Interactive actions of prostaglandin and epidermal growth factor to enhance proliferation of granulosa cells from chicken prehierarchical follicles. | Prostaglandins & other lipid mediators 20070601 |
| Inhibitory effect of cyclooxygenase inhibitors on the step-through passive avoidance performance in mice treated with NC-1900, an arginine-vasopressin fragment analog. | Methods and findings in experimental and clinical pharmacology 20070601 |
| Roles of cyclooxygenase-2 and prostaglandin E receptors in gastric mucosal defense in Helicobacter pylori-infected mice. | Inflammopharmacology 20070601 |
| Role of non-neuronal cholinergic system in breast cancer progression. | Life sciences 20070530 |
| Endothelial progenitor cells stimulate cerebrovascular production of prostacyclin by paracrine activation of cyclooxygenase-2. | Circulation research 20070511 |
| Synthesis and pharmacological evaluation of a selected library of new potential anti-inflammatory agents bearing the gamma-hydroxybutenolide scaffold: a new class of inhibitors of prostanoid production through the selective modulation of microsomal prostaglandin E synthase-1 expression. | Journal of medicinal chemistry 20070503 |
| Hypoxia inducible factor-1alpha mediates protective effects of ischemic preconditioning on ECV-304 endothelial cells. | World journal of gastroenterology 20070428 |
| Sphingosine 1-phosphate induces cyclooxygenase-2 via Ca2+-dependent, but MAPK-independent mechanism in rat vascular smooth muscle cells. | Life sciences 20070417 |
| Losartan reduces the increased participation of cyclooxygenase-2-derived products in vascular responses of hypertensive rats. | The Journal of pharmacology and experimental therapeutics 20070401 |
| Enantiomeric metabolic interactions and stereoselective human methadone metabolism. | The Journal of pharmacology and experimental therapeutics 20070401 |
| Comparison of the influence of NSAIDs with different COX-selectivity on histamine release from mast cells isolated from naïve and sensitized rats. | International immunopharmacology 20070401 |
| Effects of granulocyte colony-stimulating factor and granulocyte-macrophage colony-stimulating factor on lung cancer: roles of cyclooxygenase-2. | Oncology reports 20070401 |
| Evaluation of cyclooxygenase 2 derived endogenous prostacyclin in mouse preimplantation embryo development in vitro. | Life sciences 20070327 |
| Toll-like receptor 4 is involved in brain damage and inflammation after experimental stroke. | Circulation 20070327 |
| Interaction between cyclooxygenase (COX)-1- and COX-2-products modulates COX-2 expression in the late phase of acute inflammation. | European journal of pharmacology 20070322 |
| Modulation of the expression of peroxisome proliferators-activated receptors in human fibroblasts. | Fertility and sterility 20070301 |
| Immunomodulatory drug CC-4047 is a cell-type and stimulus-selective transcriptional inhibitor of cyclooxygenase 2. | Journal of clinical immunology 20070301 |
| An herbal medicine orengedokuto prevents indomethacin-induced enteropathy. | Biological & pharmaceutical bulletin 20070301 |
| Screening method for nonsteroidal antiinflammatory drugs based on the cyclooxygenase 2 pathway activated by serum-free stimulation in A549 cells. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070301 |
| Combined inhibitory effects of green tea polyphenols and selective cyclooxygenase-2 inhibitors on the growth of human prostate cancer cells both in vitro and in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070301 |
| Effect of a cyclooxygenase-2 inhibitor on interleukin-1beta-stimulated activation of the transcription factor nuclear factor-kappa B in human gingival fibroblasts. | Journal of periodontology 20070301 |
| Angiotensin-(1-7)-induced plasticity changes in the lateral amygdala are mediated by COX-2 and NO. | Learning & memory (Cold Spring Harbor, N.Y.) 20070301 |
| Selective COX-2 inhibitor, NS-398, suppresses cellular proliferation in human hepatocellular carcinoma cell lines via cell cycle arrest. | World journal of gastroenterology 20070227 |
| Chronic inhibition of cyclooxygenase-2 induces dendritic hypertrophy and limited functional improvement following motor cortex stroke. | Neuroscience 20070223 |
| Cyclooxygenase inhibition and hyperthermia for the potentiation of the cytotoxic response in ovarian cancer cells. | Gynecologic oncology 20070201 |
| Dexamethasone inhibits epidermal growth factor-stimulated gastric epithelial cell proliferation. | The Journal of pharmacology and experimental therapeutics 20070201 |
| Mitogenic signal transduction caused by monomethylarsonous acid in human bladder cells: role in arsenic-induced carcinogenesis. | Toxicological sciences : an official journal of the Society of Toxicology 20070201 |
| Synthesis of carbon-11 labeled sulfonanilide analogues as new potential PET agents for imaging of aromatase in breast cancer. | Bioorganic & medicinal chemistry letters 20070115 |
| Intrathecally administered COX-2 but not COX-1 or COX-3 inhibitors attenuate streptozotocin-induced mechanical hyperalgesia in rats. | European journal of pharmacology 20070105 |
| Cyclooxygenase-2 is required for activated pancreatic stellate cells to respond to proinflammatory cytokines. | American journal of physiology. Cell physiology 20070101 |
| The role of arachidonic acid and its metabolites in insulin secretion from human islets of langerhans. | Diabetes 20070101 |
| Arachidonic acid inhibits osteoblast differentiation through cytosolic phospholipase A2-dependent pathway. | Oral diseases 20070101 |
| Effect of cyclooxygenase inhibition on cholesterol efflux proteins and atheromatous foam cell transformation in THP-1 human macrophages: a possible mechanism for increased cardiovascular risk. | Arthritis research & therapy 20070101 |
| Effects of prostaglandin E2 and lipopolysaccharide on osteoclastogenesis in RAW 264.7 cells. | Prostaglandins, leukotrienes, and essential fatty acids 20070101 |
| Reverse effect of aspirin: is the prothrombotic effect after aspirin discontinuation mediated by cyclooxygenase 2 inhibition? | Pathophysiology of haemostasis and thrombosis 20070101 |
| Scaffold of the cyclooxygenase-2 (COX-2) inhibitor carprofen provides Alzheimer gamma-secretase modulators. | Journal of medicinal chemistry 20061228 |
| Roles of stretch-activated cation channel and Rho-kinase in the spontaneous contraction of airway smooth muscle. | European journal of pharmacology 20061215 |
| Role for prostaglandins in the regulation of type 1 11beta-hydroxysteroid dehydrogenase in human granulosa-lutein cells. | Endocrinology 20061201 |
| Involvement of cyclooxygenase-2--prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells. | Digestive diseases and sciences 20061201 |
| Role of prostacyclin in the development of compression trauma-induced spinal cord injury in rats. | Journal of neurotrauma 20061201 |
| Cytosolic phospholipase A alpha modulates NMDA neurotoxicity in mouse hippocampal cultures. | The European journal of neuroscience 20061201 |
| Anti-inflammatory activity of the synthetic C-C biflavonoids. | The Journal of pharmacy and pharmacology 20061201 |
| Synergistic antinociceptive effects of anandamide, an endocannabinoid, and nonsteroidal anti-inflammatory drugs in peripheral tissue: a role for endogenous fatty-acid ethanolamides? | European journal of pharmacology 20061121 |
| Cyclooxygenase-2 inhibition suppresses alphavbeta6 integrin-dependent oral squamous carcinoma invasion. | Cancer research 20061115 |
| Thromboxane mediates neutrophil superoxide production in pregnancy. | American journal of obstetrics and gynecology 20061101 |
| Prostaglandin E2 release in gastric antral mucosa of guinea-pigs: basal PGE2 release by cyclo-oxygenase 2 and ACh-stimulated PGE2 release by cyclo-oxygenase 1. | Experimental physiology 20061101 |
| Identification of specific genes and pathways involved in NSAIDs-induced apoptosis of human colon cancer cells. | World journal of gastroenterology 20061028 |
| Mechanisms regulating spontaneous contractions in the bovine epididymal duct. | Biology of reproduction 20061001 |
| A selective cyclooxygenase-2 inhibitor suppresses the growth of endometriosis xenografts via antiangiogenic activity in severe combined immunodeficiency mice. | Fertility and sterility 20061001 |
| Effects of selective inhibition of cyclooxygenase and lipooxygenase pathways in follicle rupture and ovulation in the rat. | Reproduction (Cambridge, England) 20061001 |
| COX-2 is associated with cadmium-induced ICAM-1 expression in cerebrovascular endothelial cells. | Toxicology letters 20060910 |
| Hypoxia and HIF-1alpha protect A549 cells from drug-induced apoptosis. | Cell death and differentiation 20060901 |
| COX-2 contributes to the maintenance of flow-induced dilation in arterioles of eNOS-knockout mice. | American journal of physiology. Heart and circulatory physiology 20060901 |
| Inhibition of proinflammatory tumor necrosis factor-{alpha}-induced inducible nitric-oxide synthase by xanthine-based 7-[2-[4-(2-chlorobenzene)piperazinyl]ethyl]-1,3-dimethylxanthine (KMUP-1) and 7-[2-[4-(4-nitrobenzene)piperazinyl]ethyl]-1, 3-dimethylxanthine (KMUP-3) in rat trachea: The involvement of soluble guanylate cyclase and protein kinase G. | Molecular pharmacology 20060901 |
| Prostaglandin E2 produced by late induced COX-2 stimulates hippocampal neuron loss after seizure in the CA3 region. | Neuroscience research 20060901 |
| Cyclooxygenase-2 inhibitor and interferon-beta synergistically induce apoptosis in human hepatoma cells in vitro and in vivo. | International journal of oncology 20060901 |
| Complex relationship between changes in oxygenation status and changes in R*2: the case of insulin and NS-398, two inhibitors of oxygen consumption. | Magnetic resonance in medicine 20060901 |
| Non-steroidal anti-inflammatory drugs have bacteriostatic and bactericidal activity against Helicobacter pylori. | Journal of gastroenterology and hepatology 20060901 |
| Intrathecal administration of a cylcooxygenase-1, but not a cyclooxygenase-2 inhibitor, reverses the effects of laparotomy on exploratory activity in rats. | Anesthesia and analgesia 20060901 |
| 17-beta-Estradiol upregulates COX-2 in the rat oviduct. | Prostaglandins & other lipid mediators 20060901 |
| Endogenous prostaglandins E2 and F 2alpha serve as an anti-apoptotic factor against apoptosis induced by tumor necrosis factor-alpha in mouse 3T3-L1 preadipocytes. | Bioscience, biotechnology, and biochemistry 20060901 |
| COX-1 inhibition enhances scratching behaviour in NC/Nga mice with atopic dermatitis. | Experimental dermatology 20060801 |
| Resveratrol-induced cyclooxygenase-2 facilitates p53-dependent apoptosis in human breast cancer cells. | Molecular cancer therapeutics 20060801 |
| Inducible nitric oxide synthase and cyclooxgenase-2 mediate protection of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress in PC12 cells. | Life sciences 20060724 |
| Centrally administered histamine evokes the adrenal secretion of noradrenaline and adrenaline by brain cyclooxygenase-1- and thromboxane A2-mediated mechanisms in rats. | European journal of pharmacology 20060717 |
| Angiotensin II-induced calcium signaling in the afferent arteriole from rats with two-kidney, one-clip hypertension. | American journal of physiology. Renal physiology 20060701 |
| Constitutive and activation-inducible cyclooxygenase-2 expression enhances survival of chronic lymphocytic leukemia B cells. | Clinical immunology (Orlando, Fla.) 20060701 |
| Dalteparin, a low molecular weight heparin, attenuates inflammatory responses and reduces ischemia-reperfusion-induced liver injury in rats. | Critical care medicine 20060701 |
| Enhanced early vascular permeability in gelatinase B (MMP-9)-deficient mice: putative contribution of COX-1-derived PGE2 of macrophage origin. | Journal of leukocyte biology 20060701 |
| Cyclooxygenase-2 mediates the development of cortical spreading depression-induced tolerance to transient focal cerebral ischemia in rats. | Neuroscience 20060630 |
| Significance of COX-2 expression in human esophageal squamous cell carcinoma. | Carcinogenesis 20060601 |
| Prostaglandin E2 promotes cell survival of glomerular epithelial cells via the EP4 receptor. | American journal of physiology. Renal physiology 20060601 |
| Human periodontal ligament cells secrete macrophage colony-stimulating factor in response to tumor necrosis factor-alpha in vitro. | Journal of periodontology 20060601 |
| Cyclooxygenase 2 expression in vessels and nerves in reversal reaction leprosy. | The American journal of tropical medicine and hygiene 20060601 |
| Parthenolide cooperates with NS398 to inhibit growth of human hepatocellular carcinoma cells through effects on apoptosis and G0-G1 cell cycle arrest. | Molecular cancer research : MCR 20060601 |
| Profiling of eicosanoid production in the rat hippocampus during kainic acid-induced seizure: dual phase regulation and differential involvement of COX-1 and COX-2. | The Journal of biological chemistry 20060526 |
| Dual treatment with COX-2 inhibitor and sodium arsenite leads to induction of surface Fas Ligand expression and Fas-Ligand-mediated apoptosis in human melanoma cells. | Experimental cell research 20060501 |
| Dual, but not selective, COX-1 and COX-2 inhibitors, attenuate acetic acid-evoked bladder irritation in the anaesthetised female cat. | British journal of pharmacology 20060501 |
| Decidualization and maintenance of a functional prostaglandin system in human endometrial cell lines following transformation with SV40 large T antigen. | Molecular human reproduction 20060501 |
| Transforming growth factor beta regulates cyclooxygenase-2 in glomerular mesangial cells. | Kidney international 20060501 |
| Cyclooxygenase inhibitors not inhibit resting lung cancer A549 cell proliferation. | Prostaglandins, leukotrienes, and essential fatty acids 20060501 |
| Effects of COX-2 and iNOS inhibitors alone or in combination with olfactory ensheathing cell grafts after spinal cord injury. | Spine 20060501 |
| The use of nimesulide and its analogues in cancer chemoprevention. | Anti-cancer agents in medicinal chemistry 20060501 |
| Desferrioxamine, an iron chelator, enhances HIF-1alpha accumulation via cyclooxygenase-2 signaling pathway. | Biochemical and biophysical research communications 20060428 |
| COX-2 mediates morphine-induced delayed cardioprotection via an iNOS-dependent mechanism. | Life sciences 20060425 |
| The immunosuppressive effects of ciprofloxacin during human mixed lymphocyte reaction. | Clinical immunology (Orlando, Fla.) 20060401 |
| Inhibitors of COX activity preserve muscle mass in mice bearing the Lewis lung carcinoma, but not the B16 melanoma. | Research in nursing & health 20060401 |
| Lipoxin A(4) regulates bronchial epithelial cell responses to acid injury. | The American journal of pathology 20060401 |
| Selective COX-2 inhibition reduces leukocyte sticking and improves the microcirculation in TNBS colitis. | Digestive diseases and sciences 20060401 |
| Role of bile acids, prostaglandins and COX inhibitors in chronic esophagitis in a mouse model. | World journal of gastroenterology 20060321 |
| Ionizing radiation induces astrocyte gliosis through microglia activation. | Neurobiology of disease 20060301 |
| R(+)-methanandamide and other cannabinoids induce the expression of cyclooxygenase-2 and matrix metalloproteinases in human nonpigmented ciliary epithelial cells. | The Journal of pharmacology and experimental therapeutics 20060301 |
| Cyclooxygenase-2 (COX-2) is directly involved but not decisive in proliferation of human hepatocellular carcinoma cells. | Journal of cancer research and clinical oncology 20060301 |
| COX-2 inhibitors suppress lung cancer cell growth by inducing p21 via COX-2 independent signals. | Lung cancer (Amsterdam, Netherlands) 20060301 |
| Accelerative effect of a selective cyclooxygenase-2 inhibitor on Fas-mediated apoptosis in human neutrophils. | International immunopharmacology 20060301 |
| Inhibition of COX-2 aggravates neutrophil migration and pneumocyte apoptosis in surfactant-depleted rat lungs. | Pediatric research 20060301 |
| Nonsteroidal anti-inflammatory drugs inhibit the growth of C6 and U138-MG glioma cell lines. | European journal of pharmacology 20060227 |
| Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition. | Journal of medicinal chemistry 20060223 |
| Stimulation of cyclooxygenase-2 expression by bone-derived transforming growth factor-beta enhances bone metastases in breast cancer. | Cancer research 20060215 |
| Expression and function of COX isoforms in renal medulla: evidence for regulation of salt sensitivity and blood pressure. | American journal of physiology. Renal physiology 20060201 |
| Gene transfer of pro-opiomelanocortin prohormone suppressed the growth and metastasis of melanoma: involvement of alpha-melanocyte-stimulating hormone-mediated inhibition of the nuclear factor kappaB/cyclooxygenase-2 pathway. | Molecular pharmacology 20060201 |
| Involvement of COX-2 in VEGF-induced angiogenesis via P38 and JNK pathways in vascular endothelial cells. | Cardiovascular research 20060201 |
| Selective cyclooxygenase-2 inhibitors inhibit growth and induce apoptosis of bladder cancer. | Oncology reports 20060201 |
| Cyclooxygenase-2 inhibition selectively attenuates bone morphogenetic protein-6 synthesis and bone formation during guided tissue regeneration in a rat model. | Clinical oral implants research 20060201 |
| Substance P stimulates release of RANKL via COX-2 expression in human dental pulp cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060201 |
| [Effects of gastrin receptor antagonist and cyclooxygenase-2 inhibitor on proliferation and apoptosis of gastric cancer cell]. | Zhonghua yi xue za zhi 20060124 |
| Selective induction of cyclooxygenase-2 plays a role in lysophosphatidic acid regulated Fas ligand cell surface presentation. | FEBS letters 20060123 |
| alpha-Lipoic acid inhibits inflammatory bone resorption by suppressing prostaglandin E2 synthesis. | Journal of immunology (Baltimore, Md. : 1950) 20060101 |
| [Expression of cyclooxygenase (COX)-2 in astrocytic tumors and anti-tumor effects of selective COX-2 inhibitors]. | No to shinkei = Brain and nerve 20060101 |
| Cyclooxygenase-2 is involved in HIV-1 Tat-induced inflammatory responses in the brain. | Neuromolecular medicine 20060101 |
| Reduced expression of 15-lipoxygenase 2 in human head and neck carcinomas. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20060101 |
| Interaction between spontaneous and neurally mediated regulation of smooth muscle tone in the rabbit corpus cavernosum. | The Journal of physiology 20051215 |
| Prostaglandin E2 strongly inhibits human osteoclast formation. | Endocrinology 20051201 |
| Differential effects of COX inhibitors against beta-amyloid-induced neurotoxicity in human neuroblastoma cells. | Neurochemistry international 20051201 |
| Inhibitors of arachidonic acid metabolism act synergistically to signal apoptosis in neoplastic cells. | Prostaglandins, leukotrienes, and essential fatty acids 20051201 |
| Stimulation of prostaglandin E2 (PGE2) production by arachidonic acid, oestrogen and parathyroid hormone in MG-63 and MC3T3-E1 osteoblast-like cells. | Prostaglandins, leukotrienes, and essential fatty acids 20051201 |
| Cyclooxygenase 2 (COX-2) inhibition increases the inflammatory response in the brain during systemic immune stimuli. | Journal of neurochemistry 20051201 |
| Inhibition by licochalcone A, a novel flavonoid isolated from liquorice root, of IL-1beta-induced PGE2 production in human skin fibroblasts. | The Journal of pharmacy and pharmacology 20051201 |
| Lipoxygenase pathway of arachidonic acid metabolism in growth control of tumor cells of different type. | Biochemistry. Biokhimiia 20051201 |
| Inhibition of cyclooxygenase-2 enhances myocardial damage in a mouse model of viral myocarditis. | Life sciences 20051126 |
| Involvement of prostaglandins in an animal model of Shigella-related seizures. | Journal of neuroimmunology 20051101 |
| Acetylcholine-induced endothelium-dependent contractions in the SHR aorta: the Janus face of prostacyclin. | British journal of pharmacology 20051101 |
| Peroxisome proliferator-activated receptor gamma mediates protection against cyclooxygenase-2-induced gut dysfunction in a rodent model of mesenteric ischemia/reperfusion. | Shock (Augusta, Ga.) 20051101 |
| Local simvastatin effects on mandibular bone growth and inflammation. | Journal of periodontology 20051101 |
| Celecoxib and NS-398 enhance photodynamic therapy by increasing in vitro apoptosis and decreasing in vivo inflammatory and angiogenic factors. | Cancer research 20051015 |
| Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2-dependent mechanisms. | Nature medicine 20051001 |
| Ageing affects nitric oxide synthase, cyclooxygenase and oxidative stress enzymes expression differently in mesenteric resistance arteries. | Autonomic & autacoid pharmacology 20051001 |
| Induction of cyclooxygenase-2 expression in human pulp cells stimulated by dentin bonding agents. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20051001 |
| NS-398, a cyclooxygenase-2-specific inhibitor, delays skeletal muscle healing by decreasing regeneration and promoting fibrosis. | The American journal of pathology 20051001 |
| Radiation sensitivity of human carcinoma cells transfected with small interfering RNA targeted against cyclooxygenase-2. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051001 |
| Selective cyclooxygenase 2 inhibitor induces indefinite survival of fully allogeneic cardiac grafts and generates CD4+ regulatory cells. | The Journal of thoracic and cardiovascular surgery 20051001 |
| [NS398 induced apoptosis in pancreatic carcinoma cell strain BxPC-3 through a COX-2-in dependent pathway]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20051001 |
| Lysophosphatidic acid transactivates both c-Met and epidermal growth factor receptor, and induces cyclooxygenase-2 expression in human colon cancer LoVo cells. | World journal of gastroenterology 20050928 |
| [Molecular mechanism of cyclooxygenase-2 inhibitor in inhibition of proliferation of colon cancer cells by modulating Stat5 signal transduction pathway]. | Zhonghua yi xue za zhi 20050921 |
| COX-2 inhibitors suppress integrin alpha5 expression in human lung carcinoma cells through activation of Erk: involvement of Sp1 and AP-1 sites. | International journal of cancer 20050910 |
| COX-2 up-regulation and vascular smooth muscle contractile hyperreactivity in spontaneous diabetic db/db mice. | Cardiovascular research 20050901 |
| Cyclooxygenase-2 promotes early atherosclerotic lesion formation in ApoE-deficient and C57BL/6 mice. | Journal of molecular and cellular cardiology 20050901 |
| Central cyclooxygenase inhibitors reduced IL-1beta-induced hyperalgesia in temporomandibular joint of freely moving rats. | Pain 20050901 |
| Tumor radiosensitization by antiinflammatory drugs: evidence for a new mechanism involving the oxygen effect. | Cancer research 20050901 |
| Cyclooxygenase-2-mediated DNA damage. | The Journal of biological chemistry 20050805 |
| Activation of phosphoinositide 3-kinase in response to inflammation and nitric oxide leads to the up-regulation of cyclooxygenase-2 expression and subsequent cell proliferation in mesangial cells. | Cellular signalling 20050801 |
| Vitamin E prevents the neuronal cell death by repressing cyclooxygenase-2 activity. | Neuroreport 20050801 |
| Mast cell tryptase stimulates DLD-1 carcinoma through prostaglandin- and MAP kinase-dependent manners. | Journal of pharmacological sciences 20050801 |
| NS-398, a selective cyclooxygenase-2 inhibitor, reduces experimental bladder carcinoma outgrowth by inhibiting tumor cell proliferation. | Urology 20050801 |
| [The clinical strategy for the Barrett's esophagus]. | Nihon rinsho. Japanese journal of clinical medicine 20050801 |
| COX-1 and COX-2 conversely promote and suppress ischemia-reperfusion gastric injury in mice. | Scandinavian journal of gastroenterology 20050801 |
| Effect of NS398 on metastasis-associated gene expression in a human colon cancer cell line. | World journal of gastroenterology 20050728 |
| Resistance of prostate cancer cell lines to COX-2 inhibitor treatment. | Biochemical and biophysical research communications 20050708 |
| The anti-inflammatory prostaglandin 15d-PGJ2 decreases oxidative/nitrosative mediators in brain after acute stress in rats. | Psychopharmacology 20050701 |
| Diazoxide preserves hypercapnia-induced arteriolar vasodilation after global cerebral ischemia in piglets. | American journal of physiology. Heart and circulatory physiology 20050701 |
| Interleukin-1beta-induced prostaglandin E2 production by human gingival fibroblasts is upregulated by glycine. | Journal of periodontology 20050701 |
| [Effects of selective cyclooxygenase-2 inhibitor NS-398 on proliferation and cell cycle progression of hepatocarcinoma cells]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20050701 |
| Inhibition of gastric cancer-associated angiogenesis by antisense COX-2 transfectants. | Cancer letters 20050628 |
| Clostridium difficile toxin A regulates inducible cyclooxygenase-2 and prostaglandin E2 synthesis in colonocytes via reactive oxygen species and activation of p38 MAPK. | The Journal of biological chemistry 20050603 |
| Progestogens stimulate prostacyclin production by human endothelial cells. | Human reproduction (Oxford, England) 20050601 |
| Role of 15-deoxy delta(12,14) prostaglandin J2 and Nrf2 pathways in protection against acute lung injury. | American journal of respiratory and critical care medicine 20050601 |
| Role of omega-3 polyunsaturated fatty acids on cyclooxygenase-2 metabolism in brain-metastatic melanoma. | Journal of lipid research 20050601 |
| Prediction of poor survival by cyclooxygenase-2 in patients with T4 nasopharyngeal cancer treated by radiation therapy: clinical and in vitro studies. | Head & neck 20050601 |
| Selective inhibitors differentially affect cyclooxygenase-dependent pial arteriolar responses in newborn pigs. | Pediatric research 20050601 |
| Activation of the epidermal growth factor receptor in optic nerve astrocytes leads to early and transient induction of cyclooxygenase-2. | Investigative ophthalmology & visual science 20050601 |
| Stimulatory effects of eicosanoids on ovarian angiogenesis in early luteal phase in cyclooxygenase-2 inhibitor-treated rats. | European journal of pharmacology 20050601 |
| Cyclooxygenase-2-dependent prostaglandin (PG) E2 downregulates matrix metalloproteinase-3 production via EP2/EP4 subtypes of PGE2 receptors in human periodontal ligament cells stimulated with interleukin-1alpha. | Journal of periodontology 20050601 |
| Cyclooxygenase-1 mediates the final stage of morphine-induced delayed cardioprotection in concert with cyclooxygenase-2. | Journal of the American College of Cardiology 20050517 |
| Cytokines upregulate vascular endothelial growth factor secretion by human airway smooth muscle cells: Role of endogenous prostanoids. | FEBS letters 20050509 |
| Cyclo-oxygenase-2, endothelium and aortic reactivity during deoxycorticosterone acetate salt-induced hypertension. | Journal of hypertension 20050501 |
| Translational studies on aromatase, cyclooxygenases, and enzyme inhibitors in breast cancer. | The Journal of steroid biochemistry and molecular biology 20050501 |
| Prostaglandin D(2) and J(2) induce apoptosis in human leukemia cells via activation of the caspase 3 cascade and production of reactive oxygen species. | Biochimica et biophysica acta 20050415 |
| Acetaminophen-sensitive prostaglandin production in rat cerebral endothelial cells. | American journal of physiology. Regulatory, integrative and comparative physiology 20050401 |
| Sphingosine 1-phosphate receptors mediate the lipid-induced cAMP accumulation through cyclooxygenase-2/prostaglandin I2 pathway in human coronary artery smooth muscle cells. | Molecular pharmacology 20050401 |
| Stimulation of hepatocyte survival and suppression of CCl4-induced liver injury by the adenovirally introduced C/EBPbeta gene. | Biochemical and biophysical research communications 20050401 |
| Er:YAG laser irradiation increases prostaglandin E production via the induction of cyclooxygenase-2 mRNA in human gingival fibroblasts. | Journal of periodontal research 20050401 |
| Uncoupling of oxidative phosphorylation and Smac/DIABLO release are not sufficient to account for induction of apoptosis by sulindac sulfide in human colorectal cancer cells. | International journal of oncology 20050401 |
| Hypertension increases the participation of vasoconstrictor prostanoids from cyclooxygenase-2 in phenylephrine responses. | Journal of hypertension 20050401 |
| Hypoxia upregulates cyclooxygenase-2 and prostaglandin E(2) levels in human peritoneal fibroblasts. | Fertility and sterility 20050401 |
| Age-related loss of neuronal nicotinic receptor expression in the aging mouse hippocampus corresponds with cyclooxygenase-2 and PPAR gamma expression and is altered by long-term NS398 administration. | Journal of neurobiology 20050301 |
| Selective cyclooxygenase 2 inhibitor NS-398 induces apoptosis in myeloma cells via a Bcl-2 independent pathway. | Leukemia & lymphoma 20050301 |
| Significant anti-proliferation of human endometrial cancer cells by combined treatment with a selective COX-2 inhibitor NS398 and specific MEK inhibitor U0126. | International journal of oncology 20050301 |
| Interplay among cardiotrophin-1, prostaglandins, and vascular endothelial growth factor in rat liver regeneration. | Hepatology (Baltimore, Md.) 20050301 |
| COX-2 inhibitor, NS398, enhances Fas-mediated apoptosis via modulation of the PTEN-Akt pathway in human gastric carcinoma cell lines. | DNA and cell biology 20050301 |
| Killing tumor cells: the effect of photodynamic therapy using mono-L-aspartyl chlorine and NS-398. | American journal of surgery 20050301 |
| Induced microsomal PGE synthase-1 is involved in cyclooxygenase-2-dependent PGE2 production in gastric fibroblasts. | American journal of physiology. Gastrointestinal and liver physiology 20050201 |
| Role of COX-2, thromboxane A2 synthase, and prostaglandin I2 synthase in papillary thyroid carcinoma growth. | Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20050201 |
| Down-regulation of interleukin-1alpha-induced matrix metalloproteinase-13 expression via EP1 receptors by prostaglandin E2 in human periodontal ligament cells. | Oral microbiology and immunology 20050201 |
| In vivo endothelial interaction between ACE and COX inhibitors. | Prostaglandins, leukotrienes, and essential fatty acids 20050201 |
| COX-2 correlates with F-box protein, Skp2 expression and prognosis in human gastric carcinoma. | International journal of oncology 20050201 |
| The role of selective nitric oxide synthase inhibitor on nitric oxide and PGE2 levels in refractory hemorrhagic-shocked rats. | The Journal of surgical research 20050201 |
| Modulation of the expression of vascular endothelial growth factor in human fibroblasts. | Fertility and sterility 20050201 |
| Effect of NS-398 on colon cancer cells. | World journal of gastroenterology 20050121 |
| Specific COX-2 inhibitor NS398 induces apoptosis in human liver cancer cell line HepG2 through BCL-2. | World journal of gastroenterology 20050114 |
| Tumor necrosis factor alpha and interleukin-1beta stimulate the expression of cyclooxygenase II but do not alter prostaglandin E2 receptor mRNA levels in cultured dorsal root ganglia cells. | Pain 20050101 |
| Selective inhibitors of MEK1/ERK44/42 and p38 mitogen-activated protein kinases potentiate apoptosis induction by sulindac sulfide in human colon carcinoma cells. | Molecular cancer therapeutics 20050101 |
| Celecoxib inhibits ureteral contractility and prostanoid release. | Urology 20050101 |
| Effects of sodium restriction and cyclooxygenase-2 inhibition on the course of hypertension, proteinuria and cardiac hypertrophy in Ren-2 transgenic rats. | Physiological research 20050101 |
| Cyclooxygenase-2 increases hypoxia-inducible factor-1 and vascular endothelial growth factor to promote angiogenesis in gastric carcinoma. | Journal of biomedical science 20050101 |
| Autocrine vascular endothelial growth factor/vascular endothelial growth factor receptor-2 growth pathway represents a cyclooxygenase-2-independent target for the cyclooxygenase-2 inhibitor NS-398 in colon cancer cells. | Oncology 20050101 |
| Pancreatic stellate cells (PSCs) express cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs. | Molecular cancer 20050101 |
| Prostaglandin F2alpha produced by inducible cyclooxygenase may contribute to the resolution of inflammation. | Inflammopharmacology 20050101 |
| Endothelial cell confluence regulates cyclooxygenase-2 and prostaglandin E2 production that modulate motility. | The Journal of biological chemistry 20041231 |
| Cyclooxygenase-2 activity contributes to neuronal expression of cyclin D1 after anoxia/ischemia in vitro and in vivo. | Brain research. Molecular brain research 20041206 |
| Nitric oxide synthase-inhibition hypertension is associated with altered endothelial cyclooxygenase function. | American journal of physiology. Heart and circulatory physiology 20041201 |
| Oviduct prostacyclin functions as a paracrine factor to augment the development of embryos. | Human reproduction (Oxford, England) 20041201 |
| Study of prostaglandin receptors in mitochondria on apoptosis of human lung carcinoma cell line A549. | Biochemical Society transactions 20041201 |
| Cyclooxygenase-2 inhibitor preserves medullary aquaporin-2 expression and prevents polyuria after ureteral obstruction. | The Journal of urology 20041201 |
| Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells. | Journal of the National Cancer Institute 20041201 |
| NS398 reduces hypoxia-inducible factor (HIF)-1alpha and HIF-1 activity: multiple-level effects involving cyclooxygenase-2 dependent and independent mechanisms. | International journal of cancer 20041120 |
| Cigarette smoke induces cyclooxygenase-2 and microsomal prostaglandin E2 synthase in human lung fibroblasts: implications for lung inflammation and cancer. | American journal of physiology. Lung cellular and molecular physiology 20041101 |
| A cyclooxygenase metabolite of anandamide causes inhibition of interleukin-2 secretion in murine splenocytes. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Implication of prostaglandin E(2) in TNF-alpha-induced release of m-calpain from HCS-2/8 chondrocytes. Inhibition of m-calpain release by NSAIDs. | Osteoarthritis and cartilage 20041101 |
| Effect of low- and high-intensity pulsed ultrasound on collagen post-translational modifications in MC3T3-E1 osteoblasts. | Calcified tissue international 20041101 |
| Endothelin-1 induces cyclooxygenase-2 expression and generation of reactive oxygen species in endothelial cells. | Journal of cardiovascular pharmacology 20041101 |
| Targeting cyclooxygenase-2 with sodium butyrate and NSAIDs on colorectal adenoma/carcinoma cells. | World journal of gastroenterology 20041015 |
| Preemptive effects of intrathecal cyclooxygenase inhibitor or nitric oxide synthase inhibitor on thermal hypersensitivity following peripheral nerve injury. | Life sciences 20041008 |
| Selective inhibition of cyclooxygenase-2 enhances platelet adhesion in hamster arterioles in vivo. | Circulation 20041005 |
| Synthetic and naturally occurring COX-2 inhibitors suppress proliferation in a human oesophageal adenocarcinoma cell line (OE33) by inducing apoptosis and cell cycle arrest. | Carcinogenesis 20041001 |
| Non-steroidal anti-inflammatory drug activated gene (NAG-1) expression is closely related to death receptor-4 and -5 induction, which may explain sulindac sulfide induced gastric cancer cell apoptosis. | Carcinogenesis 20041001 |
| Inhibition of cyclooxygenase-2 in the rat renal medulla leads to sodium-sensitive hypertension. | Hypertension (Dallas, Tex. : 1979) 20041001 |
| Role of cyclooxygenase-1 and -2 in satellite cell proliferation, differentiation, and fusion. | Muscle & nerve 20041001 |
| Dose-dependent immunomodulatory effects of acetylsalicylic acid and indomethacin in human whole blood: potential role of cyclooxygenase-2 inhibition. | Scandinavian journal of immunology 20041001 |
| Sensitization of vanilloid receptor 1 induced by bradykinin via the activation of second messenger signaling cascades in rat primary afferent neurons. | European journal of pharmacology 20040913 |
| Regulation of bone morphogenetic protein-2 expression by endogenous prostaglandin E2 in human mesenchymal stem cells. | Journal of cellular physiology 20040901 |
| COX-2 Regulates the insulin-like growth factor I-induced potentiation of Zn(2+)-toxicity in primary cortical culture. | Molecular pharmacology 20040901 |
| NS-398 inhibits tumor growth and liver metastasis of colon cancer through induction of apoptosis and suppression of the plasminogen activation system in a mouse model. | Journal of the American College of Surgeons 20040901 |
| Role of prostaglandins and nitric oxide in the lipopolysaccharide-induced ACTH and corticosterone response. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20040901 |
| Potential antipsoriatic avarol derivatives as antioxidants and inhibitors of PGE(2) generation and proliferation in the HaCaT cell line. | Journal of natural products 20040901 |
| Antitussive effect of NS-398, a selective cyclooxygenase-2 inhibitor, in guinea pigs. | European journal of pharmacology 20040823 |
| Prostaglandin E2 inhibits transforming growth factor beta 1-mediated induction of collagen alpha 1(I) in hepatic stellate cells. | Journal of hepatology 20040801 |
| Expression and enzyme activity determination of human cyclooxygenase-1 and -2 in a baculovirus-insect cell system. | Acta pharmacologica Sinica 20040801 |
| NSAIDs activate PTEN and other phosphatases in human colon cancer cells: novel mechanism for chemopreventive action of NSAIDs. | Biochemical and biophysical research communications 20040730 |
| Inhibition of cyclooxygenase-1 and -2 expression by targeting the endothelin a receptor in human ovarian carcinoma cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040715 |
| Gastrin-induced cyclooxygenase-2 expression in Barrett's carcinogenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040715 |
| Hypertension alters role of iNOS, COX-2, and oxidative stress in bradykinin relaxation impairment after LPS in rat cerebral arteries. | American journal of physiology. Heart and circulatory physiology 20040701 |
| Involvement of cyclooxygenase-2 in rat models of conjunctivitis. | Current eye research 20040701 |
| Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes. | Experimental & molecular medicine 20040630 |
| Opposing effects of cyclooxygenase-2 selective inhibitors on oxygen-glucose deprivation-induced neurotoxicity. | European journal of pharmacology 20040616 |
| Antiproliferative and apoptotic effects of rofecoxib on esophageal cancer in vitro(1). | The Journal of surgical research 20040615 |
| In vivo study on cross talk between inducible nitric-oxide synthase and cyclooxygenase in rat gastric mucosa: effect of cyclooxygenase activity on nitric oxide production. | The Journal of pharmacology and experimental therapeutics 20040601 |
| Expression of cyclooxygenase-2 (COX-2) in human esophageal cancer and in vitro inhibition by a specific COX-2 inhibitor, NS-398. | Journal of gastroenterology and hepatology 20040601 |
| Induction of cyclooxygenase-1 in cultured synovial cells isolated from rheumatoid arthritis patients. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20040601 |
| Determination of expression of cyclooxygenase-1 and -2 isozymes in canine tissues and their differential sensitivity to nonsteroidal anti-inflammatory drugs. | American journal of veterinary research 20040601 |
| Inhibition of intrafollicular PGE2 synthesis and ovulation following ultrasound-mediated intrafollicular injection of the selective cyclooxygenase-2 inhibitor NS-398 in cattle. | Journal of animal science 20040601 |
| A selective cyclooxygenase-2 inhibitor, NS398, inhibits cell growth and induces cell cycle arrest in the G2/M phase in human esophageal squamous cell carcinoma cells. | Journal of experimental & clinical cancer research : CR 20040601 |
| COX-2 and iNOS in opioid-induced delayed cardioprotection in the intact rat. | Life sciences 20040528 |
| Simple aromatic compounds containing propenone moiety show considerable dual COX/5-LOX inhibitory activities. | Bioorganic & medicinal chemistry letters 20040517 |
| Integrin-linked kinase (ILK) regulation of the cell viability in PTEN mutant glioblastoma and in vitro inhibition by the specific COX-2 inhibitor NS-398. | Cancer letters 20040510 |
| Akt regulates COX-2 mRNA and protein expression in mutated-PTEN human endometrial cancer cells. | International journal of oncology 20040501 |
| Selective COX-2 inhibitor, NS-398, inhibits the replicative senescence of cultured dermal fibroblasts. | Mechanisms of ageing and development 20040501 |
| Screening anti-inflammatory compounds in injured spinal cord with microarrays: a comparison of bioinformatics analysis approaches. | Physiological genomics 20040413 |
| [Effects of selective cyclooxygenase-2 inhibitor NS-398 on 5-fluorouracil chemotherapy and progression of colon cells: an experimental study]. | Zhonghua yi xue za zhi 20040402 |
| Inhibition of cyclooxygenase-2 improves cardiac function after myocardial infarction in the mouse. | American journal of physiology. Heart and circulatory physiology 20040401 |
| Doxycycline inhibits cell proliferation and invasive potential: combination therapy with cyclooxygenase-2 inhibitor in human colorectal cancer cells. | The Journal of laboratory and clinical medicine 20040401 |
| Inhibition of IL-6, TNF-alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells. | Cellular immunology 20040401 |
| Effect of bismuth subgallate on nitric oxide and prostaglandin E2 production by macrophages. | Biochemical and biophysical research communications 20040319 |
| A new pyrazolo pyrimidine derivative inhibitor of cyclooxygenase-2 with anti-angiogenic activity. | European journal of pharmacology 20040319 |
| Synthesis and inhibitory activity against COX-2 catalyzed prostaglandin production of chrysin derivatives. | Bioorganic & medicinal chemistry letters 20040308 |
| Redox regulates COX-2 upregulation and cell death in the neuronal response to cadmium. | Cellular signalling 20040301 |
| Significance of COX-2 expression in human renal cell carcinoma cell lines. | International journal of cancer 20040301 |
| Constitutive expression and involvement of cyclooxygenase-2 in human megakaryocytopoiesis. | Arteriosclerosis, thrombosis, and vascular biology 20040301 |
| Intraparenchymal administration of interleukin-1beta induces cyclooxygenase-2-mediated expression of membrane- and cytosolic-associated prostaglandin E synthases in mouse brain. | Journal of neuroimmunology 20040301 |
| Examination of the signal transduction pathways involved in matrix metalloproteinases-2 in human pulp cells. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20040301 |
| NS398 inhibits the growth of Hep3B human hepatocellular carcinoma cells via caspase-independent apoptosis. | Molecules and cells 20040227 |
| Interleukin-1beta, transforming growth factor-beta1, and bradykinin attenuate cyclic AMP production by human pulmonary artery smooth muscle cells in response to prostacyclin analogues and prostaglandin E2 by cyclooxygenase-2 induction and downregulation of adenylyl cyclase isoforms 1, 2, and 4. | Circulation research 20040220 |
| Novel regulatory mechanisms of CD40-induced prostanoid synthesis by IL-4 and IL-10 in human monocytes. | Journal of immunology (Baltimore, Md. : 1950) 20040215 |
| Cyclooxygenase-2 is essential for HER2/neu to suppress N- (4-hydroxyphenyl)retinamide apoptotic effects in breast cancer cells. | Cancer research 20040215 |
| Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer. | British journal of cancer 20040209 |
| Protease-activated receptor-2-mediated contraction of urinary bladder is enhanced in cyclophosphamide-treated rats. | Naunyn-Schmiedeberg's archives of pharmacology 20040201 |
| Effects of chronic PGHS-2 inhibition on PGHS-dependent vasoconstriction in the aged female rat. | Cardiovascular research 20040201 |
| Inhibition of human glioma cell growth by a PHS-2 inhibitor, NS398, and a prostaglandin E receptor subtype EP1-selective antagonist, SC51089. | Journal of neuro-oncology 20040201 |
| Interferon-tau blocks the stimulatory effect of tumor necrosis factor-alpha on prostaglandin F2alpha synthesis by bovine endometrial stromal cells. | Biology of reproduction 20040101 |
| TNFR1 mediates the radioprotective effects of lipopolysaccharide in the mouse intestine. | American journal of physiology. Gastrointestinal and liver physiology 20040101 |
| Influence of interleukin-1alpha and COX-2 over the metabolism of arachidonic acid and glucose in isolated uterus of restricted diet rats. | Prostaglandins, leukotrienes, and essential fatty acids 20040101 |
| Role of polymorphonuclear leukocytes, nitric oxide synthase, and cyclooxygenase in vascular permeability changes induced by C5a agonist peptides. | Molecular cancer therapeutics 20040101 |
| Pro/antioxidant status in murine skin following topical exposure to cumene hydroperoxide throughout the ontogeny of skin cancer. | Biochemistry. Biokhimiia 20040101 |
| Inhibition of cyclooxygenase-2 by NS-398 following hemorrhage and subsequent sepsis: no beneficial effects in either gender. | Surgical infections 20040101 |
| Oncostatin M stimulates the detachment of a reservoir of invasive mammary carcinoma cells: role of cyclooxygenase-2. | Clinical & experimental metastasis 20040101 |
| Raloxifene increases the capacity of serum to promote prostacyclin release in human endothelial cells: implication of COX-1 and COX-2. | Menopause (New York, N.Y.) 20040101 |
| Hydrodynamic shear stimulates osteocalcin expression but not proliferation of bone marrow stromal cells. | Tissue engineering 20040101 |
| Acute effects of cyclooxygenase-2 inhibition on renal function in heterozygous ren-2-transgenic rats on normal or low sodium intake. | Kidney & blood pressure research 20040101 |
| COX-2 inhibition and cancer: experimental findings and clinical correlates. | The West Virginia medical journal 20040101 |
| Inhibition of cyclooxygenase-2 suppresses invasiveness of oral squamous cell carcinoma cell lines via down-regulation of matrix metalloproteinase-2 and CD44. | Clinical & experimental metastasis 20040101 |
| Up-regulation of cyclooxygenase-2 and apoptosis resistance by p38 MAPK in hypericin-mediated photodynamic therapy of human cancer cells. | The Journal of biological chemistry 20031226 |
| Increased TNFalpha production and Cox-2 activity in organotypic brain slice cultures from APPsw transgenic mice. | Neuroscience letters 20031215 |
| Nonsteroidal anti-inflammatory drugs inhibit growth of human neuroendocrine tumor cells via G1 cell-cycle arrest. | International journal of cancer 20031210 |
| Role of COX-1 and -2 in prostanoid generation and modulation of angiotensin II responses. | American journal of physiology. Heart and circulatory physiology 20031201 |
| NS 398 radiosensitizes an HNSCC cell line by possibly inhibiting radiation-induced expression of COX-2. | International journal of radiation oncology, biology, physics 20031201 |
| Novel combination of cyclooxygenase-2 and MEK inhibitors in human hepatocellular carcinoma provides a synergistic increase in apoptosis. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20031201 |
| COX-2 is essential for EGF induction of cell proliferation in gastric RGM1 cells. | Digestive diseases and sciences 20031201 |
| Influence of cyclooxygenase inhibitors on the central histaminergic stimulations of hypothalamic - pituitary - adrenal axis. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20031201 |
| Induction of G0/G1 cell cycle arrest in ovarian carcinoma cells by the anti-inflammatory drug NS-398, but not by COX-2-specific RNA interference. | Oncogene 20031127 |
| Enhancement of chemotherapeutic drug-induced apoptosis by a cyclooxygenase-2 inhibitor in hypopharyngeal carcinoma cells. | Cancer letters 20031125 |
| Lipid a radiosensitizes hypoxic EMT-6 tumor cells: role of the NF-kappaB signaling pathway. | International journal of radiation oncology, biology, physics 20031101 |
| Cyclooxygenase-2 inhibitor NS398 enhances antitumor effect of irradiation on hormone refractory human prostate carcinoma cells. | The Journal of urology 20031101 |
| Inhibition of cyclooxygenase-2 with NS-398 and the prevention of radiation-induced transformation, micronuclei formation and clonogenic cell death in C3H 10T1/2 cells. | International journal of radiation biology 20031101 |
| Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells. | British journal of cancer 20031006 |
| Effects of hypoxia on monocyte inflammatory mediator production: Dissociation between changes in cyclooxygenase-2 expression and eicosanoid synthesis. | The Journal of biological chemistry 20031003 |
| Induction of cyclooxygenase-2 mRNA and protein expression in human gingival fibroblasts stimulated with nicotine. | Journal of periodontal research 20031001 |
| Suppressive effect of selective cyclooxygenase-2 inhibitor on cytokine release in human neutrophils. | International immunopharmacology 20031001 |
| Leukotriene D4-induced adhesion of Caco-2 cells is mediated by prostaglandin E2 and upregulation of alpha2beta1-integrin. | Experimental cell research 20031001 |
| Evaluation of the contribution of cyclooxygenase 1 and cyclooxygenase 2 to the production of PGE2 and PGF2 alpha in epithelial cells from bovine endometrium. | Reproduction (Cambridge, England) 20031001 |
| Control of COX-2 gene expression through peroxisome proliferator-activated receptor gamma in human cervical cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031001 |
| COX-2/VEGF-dependent facilitation of tumor-associated angiogenesis and tumor growth in vivo. | Laboratory investigation; a journal of technical methods and pathology 20031001 |
| Cyclooxygenase-2 (COX-2) inhibitors sensitize tumor cells specifically to death receptor-induced apoptosis independently of COX-2 inhibition. | Oncogene 20030911 |
| Induction of cyclooxygenase-2 accounts for restraint stress-induced oxidative status in rat brain. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030901 |
| Lipopolysaccharide-induced dopaminergic cell death in rat midbrain slice cultures: role of inducible nitric oxide synthase and protection by indomethacin. | Journal of neurochemistry 20030901 |
| Relationship between cyclooxygenase-2 and nitric oxide synthase-2 in rat cortex after stress. | The European journal of neuroscience 20030901 |
| Cyclooxygenase 2 and intermittent hypoxia-induced spatial deficits in the rat. | American journal of respiratory and critical care medicine 20030815 |
| Aspirin protects Caco-2 cells from apoptosis after serum deprivation through the activation of a phosphatidylinositol 3-kinase/AKT/p21Cip/WAF1pathway. | Molecular pharmacology 20030801 |
| Free radicals and the pathogenesis of type 1 diabetes: beta-cell cytokine-mediated free radical generation via cyclooxygenase-2. | Diabetes 20030801 |
| COX-2 inhibitor as a radiation enhancer: new strategies for the treatment of lung cancer. | American journal of clinical oncology 20030801 |
| Ibuprofen-mediated reduction of hypoxia-inducible factors HIF-1alpha and HIF-2alpha in prostate cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030801 |
| Molecular mechanisms involved in the antiproliferative effect of two COX-2 inhibitors, nimesulide and NS-398, on colorectal cancer cell lines. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20030801 |
| A cyclooxygenase-2 inhibitor attenuates spontaneous and TNF-alpha-induced non-rapid eye movement sleep in rabbits. | American journal of physiology. Regulatory, integrative and comparative physiology 20030701 |
| Inhibitors of cyclooxygenase-2, but not cyclooxygenase-1 provide structural and functional protection against quinolinic acid-induced neurodegeneration. | The Journal of pharmacology and experimental therapeutics 20030701 |
| Effects of cyclooxygenase inhibitors on nitric oxide production and survival in a mice model of sepsis. | Pharmacological research 20030701 |
| Specific COX-2 inhibitor, NS-398, suppresses cellular proliferation and induces apoptosis in human hepatocellular carcinoma cells. | International journal of oncology 20030701 |
| ROCK and nuclear factor-kappaB-dependent activation of cyclooxygenase-2 by Rho GTPases: effects on tumor growth and therapeutic consequences. | Molecular biology of the cell 20030701 |
| Cyclooxygenase-2 is induced in the endothelial cells throughout the central nervous system during carrageenan-induced hind paw inflammation; its possible role in hyperalgesia. | Journal of neurochemistry 20030701 |
| [Effects of NaBT and NSAIDs on colorectal adenoma-carcinoma cells]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20030701 |
| [Inhibitory effect of NS398 on the proliferation of human ovarian cancer cell lines CAOV3 and OVCAR3 in vitro]. | Zhonghua fu chan ke za zhi 20030701 |
| The protective effect of rebamipide on paracellular permeability of rat gastric epithelial cells. | Alimentary pharmacology & therapeutics 20030701 |
| Involvement of FGF-2 in the action of Emdogain on normal human osteoblastic activity. | Oral diseases 20030701 |
| Enhancement of carcinogen-induced malignant cell transformation by prostaglandin F(2 alpha). | Toxicology 20030630 |
| Arachidonate release and prostaglandin production by group IVC phospholipase A2 (cytosolic phospholipase A2gamma). | The Biochemical journal 20030615 |
| Mechanotransduction in bone cells proceeds via activation of COX-2, but not COX-1. | Biochemical and biophysical research communications 20030606 |
| ChTX induces oscillatory contraction in guinea pig trachea: role of cyclooxygenase-2 and PGE2. | American journal of physiology. Lung cellular and molecular physiology 20030601 |
| Inhibition of cyclooxygenase-2 and activation of peroxisome proliferator-activated receptor-gamma synergistically induces apoptosis and inhibits growth of human breast cancer cells. | International journal of molecular medicine 20030601 |
| Cyclooxygenase-2-dependent superoxide generation contributes to age-dependent impairment of G protein-mediated cerebrovasodilation. | Anesthesiology 20030601 |
| COX-2: an in vivo evidence of its participation in heat stress-induced myocardial preconditioning. | Cardiovascular research 20030601 |
| Implication of cyclooxygenase-2 on enhanced proliferation of neural progenitor cells in the adult mouse hippocampus after ischemia. | Journal of neuroscience research 20030515 |
| Induction of cyclooxygenase-2 mRNA and protein expression by epoxy resin and zinc oxide-eugenol based root canal sealers in human osteoblastic cells. | Biomaterials 20030501 |
| Acetic acid-derived prostaglandin-dependent colonic adaptive cytoprotection is preserved in chronic colitis: role of cyclo-oxygenase. | International journal of colorectal disease 20030501 |
| Immunomodulatory effects of the tobacco-specific carcinogen, NNK, on alveolar macrophages. | Clinical and experimental immunology 20030501 |
| The cyclooxygenase 2-selective inhibitor NS398 inhibits proliferation of oral carcinoma cell lines by mechanisms dependent and independent of reduced prostaglandin E2 synthesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030501 |
| Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) sequentially upregulates nitric oxide and prostanoid production in primary human endothelial cells. | Circulation research 20030418 |
| Caspase-1 inhibitors abolish deleterious enhancement of COX-2 expression induced by HIV-1 gp120 in human neuroblastoma cells. | Toxicology letters 20030404 |
| Inhibition of cyclooxygenase-2: effects on renin secretion and expression in fetal lambs. | American journal of physiology. Regulatory, integrative and comparative physiology 20030401 |
| The anti-apoptotic effect of leukotriene D4 involves the prevention of caspase 8 activation and Bid cleavage. | The Biochemical journal 20030401 |
| The stable analog carbocyclic TXA2 but not platelet-released TXA2 induces osteoclast-like cell formation. | Prostaglandins, leukotrienes, and essential fatty acids 20030401 |
| Inhibited proliferation of cyclooxygenase-2 expressing human hepatoma cells by NS-398, a selective COX-2 inhibitor. | International journal of oncology 20030401 |
| Cyclooxygenase (COX) inhibitors induce apoptosis in non-small cell lung cancer through cyclooxygenase independent pathways. | Lung cancer (Amsterdam, Netherlands) 20030401 |
| Cyclooxygenase-2 inhibition improves macrophage function in melanoma and increases the antineoplastic activity of interferon gamma. | Annals of surgical oncology 20030401 |
| Crystal-induced neutrophil activation: VIII. Immediate production of prostaglandin E2 mediated by constitutive cyclooxygenase 2 in human neutrophils stimulated by urate crystals. | Arthritis and rheumatism 20030401 |
| Cyclooxygenase-2 mediates mucin secretion from epithelial cells of lipopolysaccharide-treated canine gallbladder. | Digestive diseases and sciences 20030401 |
| Cyclooxygenase-2 expression and role of vasoconstrictor prostanoids in small mesenteric arteries from patients with Crohn's disease. | Circulation 20030318 |
| Late administration of COX-2 inhibitors minimize hepatic necrosis in chloroform induced liver injury. | Toxicology 20030314 |
| Role of macula densa cyclooxygenase-2 in renovascular hypertension. | American journal of physiology. Renal physiology 20030301 |
| The up-regulation of cyclooxygenase-2 expression in human buccal mucosal fibroblasts by arecoline: a possible role in the pathogenesis of oral submucous fibrosis. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20030301 |
| A role for COX-2 and p38 mitogen activated protein kinase in long-term depression in the rat dentate gyrus in vitro. | Neuropharmacology 20030301 |
| Inhibition of COX-2 prevents hypertension and proteinuria associated with a decrease of 8-iso-PGF2alpha formation in L-NAME-treated rats. | Journal of hypertension 20030301 |
| Inhibition of paclitaxel-induced apoptosis by the specific COX-2 inhibitor, NS398, in epithelial ovarian cancer cells. | Gynecologic oncology 20030301 |
| Cyclooxygenase-2 mediates interleukin-6 upregulation by vomitoxin (deoxynivalenol) in vitro and in vivo. | Toxicology and applied pharmacology 20030301 |
| Reduced 15S-lipoxygenase-2 expression in esophageal cancer specimens and cells and upregulation in vitro by the cyclooxygenase-2 inhibitor, NS398. | Neoplasia (New York, N.Y.) 20030301 |
| Effect of cyclooxygenase inhibitors on the CRH-induced pituitary-adrenocortical activity during crowding stress. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030301 |
| Role of cyclooxygenases COX-1 and COX-2 in modulating adipogenesis in 3T3-L1 cells. | Journal of lipid research 20030201 |
| Cyclooxygenase-2 and inducible nitric oxide synthase in omental arteries harvested from patients with severe liver diseases: immuno-localization and influence on vascular tone. | Intensive care medicine 20030201 |
| Cyclooxygenase-2 inhibitor NS-398 suppresses cell growth and constitutive production of granulocyte-colony stimulating factor and granulocyte macrophage-colony stimulating factor in lung cancer cells. | Cancer science 20030201 |
| NS-398 and piroxicam suppress UVB-induced activator protein 1 activity by mechanisms independent of cyclooxygenase-2. | The Journal of biological chemistry 20030124 |
| Delayed effect of administration of COX-2 inhibitor in mice with acute cerebral ischemia. | Brain research 20030117 |
| Cyclooxygenase-2 expression by nonsteroidal anti-inflammatory drugs in human airway smooth muscle cells: role of peroxisome proliferator-activated receptors. | Journal of immunology (Baltimore, Md. : 1950) 20030115 |
| Neuroprotection of cultured cortical neurons mediated by the cyclooxygenase-2 inhibitor APHS can be reversed by a prostanoid. | Journal of neuroscience research 20030101 |
| NS-398, a selective cyclooxygenase-2 blocker, acutely inhibits receptor-mediated contractions of rat aorta: role of endothelium. | European journal of pharmacology 20030101 |
| Study of the mechanisms involved in the bradykinin-induced contraction of the pig iris sphincter muscle in vitro. | European journal of pharmacology 20030101 |
| Trefoil peptides as proangiogenic factors in vivo and in vitro: implication of cyclooxygenase-2 and EGF receptor signaling. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030101 |
| Interleukin-1beta induces glycosaminoglycan synthesis via the prostaglandin E2 pathway in cultured human cervical fibroblasts. | Molecular human reproduction 20030101 |
| Potential involvement of the cyclooxygenase-2 pathway in the regulation of tumor-associated angiogenesis and growth in pancreatic cancer. | Molecular cancer therapeutics 20030101 |
| Effect of H. pylori infection on the expression of cyclooxygenase-2 in human gastric mucosa. | Prostaglandins, leukotrienes, and essential fatty acids 20030101 |
| COX-2 inhibition potentiates the antiproteinuric effect of enalapril in uninephrectomized SHR. | Prostaglandins, leukotrienes, and essential fatty acids 20030101 |
| Physiological apoptotic agents have different effects upon human amnion epithelial and mesenchymal cells. | Placenta 20030101 |
| T-cell proliferative responses following sepsis in neonatal rats. | Biology of the neonate 20030101 |
| Selective inhibition of cyclooxygenase-2 (COX-2) reduces prostaglandin E2 production and attenuates systemic disease sequelae in experimental pancreatitis. | Hepato-gastroenterology 20030101 |
| Interaction of hepatocyte growth factor and non-steroidal anti-inflammatory drugs during gastric epithelial wound healing. | Digestion 20030101 |
| Prostaglandin levels in seminal plasma and sperm extracts of the domestic turkey, and the effects of cyclooxygenase inhibitors on sperm mobility. | Reproductive biology and endocrinology : RB&E 20030101 |
| A selective cyclooxygenase-2 inhibitor, NS-398, inhibits cell growth by cell cycle arrest in a human malignant fibrous histiocytoma cell line. | Anticancer research 20030101 |
| Prostaglandin E2 induces hypoxia-inducible factor-1alpha stabilization and nuclear localization in a human prostate cancer cell line. | The Journal of biological chemistry 20021220 |
| Insulin-like growth factor-I antagonizes the antiproliferative effects of cyclooxygenase-2 inhibitors on BxPC-3 pancreatic cancer cells. | Cancer research 20021215 |
| Gastrin enhances gastric mucosal integrity through cyclooxygenase-2 upregulation in rats. | American journal of physiology. Gastrointestinal and liver physiology 20021201 |
| COX-2-derived prostacyclin mediates opioid-induced late phase of preconditioning in isolated rat hearts. | American journal of physiology. Heart and circulatory physiology 20021201 |
| Downregulation of nNOS and synthesis of PGs associated with endotoxin-induced delay in gastric emptying. | American journal of physiology. Gastrointestinal and liver physiology 20021201 |
| Mechanisms underlying nonsteroidal anti-inflammatory drug-induced p27(Kip1) expression. | Molecular pharmacology 20021201 |
| Induction of thromboxane A2 synthesizing enzymes in DMSO-induced granulocytic differentiation of HL-60 cells. | Prostaglandins, leukotrienes, and essential fatty acids 20021201 |
| Induction of apoptosis in rheumatoid synovial fibroblasts by celecoxib, but not by other selective cyclooxygenase 2 inhibitors. | Arthritis and rheumatism 20021201 |
| Induction of RECK by nonsteroidal anti-inflammatory drugs in lung cancer cells. | Oncogene 20021128 |
| Selective cyclooxygenase-2 inhibitors show a differential ability to inhibit proliferation and induce apoptosis of colon adenocarcinoma cells. | FEBS letters 20021106 |
| Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury. | American journal of physiology. Gastrointestinal and liver physiology 20021101 |
| Delta-opioid receptor-induced late preconditioning is mediated by cyclooxygenase-2 in conscious rabbits. | American journal of physiology. Heart and circulatory physiology 20021101 |
| Cyclooxygenase-2 promotes prostate cancer progression. | The Prostate 20021101 |
| Cyclooxygenase-2 overexpression reduces apoptotic susceptibility by inhibiting the cytochrome c-dependent apoptotic pathway in human colon cancer cells. | Cancer research 20021101 |
| Wound healing involves induction of cyclooxygenase-2 expression in rat skin. | Laboratory investigation; a journal of technical methods and pathology 20021101 |
| Screening of ubiquitous plant constituents for COX-2 inhibition with a scintillation proximity based assay. | Journal of natural products 20021101 |
| Cyclooxygenase-2 inhibitor enhances whereas prostaglandin E2 inhibits the production of interferon-induced protein of 10 kDa in epidermoid carcinoma A431. | The Journal of investigative dermatology 20021101 |
| Cyclooxygenase-2 inhibitors attenuate increased blood pressure in renovascular hypertensive models, but not in deoxycorticosterone-salt hypertension. | Hypertension research : official journal of the Japanese Society of Hypertension 20021101 |
| On the interaction of specific prostaglandin H synthase-2 inhibitors with prostaglandin H synthase-1. | European journal of pharmacology 20021025 |
| Inhibition of the expression of alpha-smooth muscle actin in human hepatic stellate cell line, LI90, by a selective cyclooxygenase 2 inhibitor, NS-398. | Biochemical and biophysical research communications 20021011 |
| A role for cyclooxygenase-2 in lipopolysaccharide-induced anorexia in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20021001 |
| Superior effectiveness of ibuprofen compared with other NSAIDs for reducing the survival of human prostate cancer cells. | Cancer chemotherapy and pharmacology 20021001 |
| Cyclooxygenase-2 gene disruption attenuates the severity of acute pancreatitis and pancreatitis-associated lung injury. | Gastroenterology 20021001 |
| Basic fibroblast growth factor stimulates osteoclast recruitment, development, and bone pit resorption in association with angiogenesis in vivo on the chick chorioallantoic membrane and activates isolated avian osteoclast resorption in vitro. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20021001 |
| Activation of proteinase-activated receptor 1 stimulates epithelial chloride secretion through a unique MAP kinase- and cyclo-oxygenase-dependent pathway. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001 |
| NS-398: cyclooxygenase-2 independent inhibition of leukocyte priming for lipid body formation and enhanced leukotriene generation. | Prostaglandins, leukotrienes, and essential fatty acids 20021001 |
| Hypertension alters the participation of contractile prostanoids and superoxide anions in lipopolysaccharide effects on small mesenteric arteries. | Life sciences 20020913 |
| Bradykinin increases IL-8 generation in airway epithelial cells via COX-2-derived prostanoids. | American journal of physiology. Lung cellular and molecular physiology 20020901 |
| Estrogen replacement reduces PGHS-2-dependent vasoconstriction in the aged rat. | American journal of physiology. Heart and circulatory physiology 20020901 |
| Cyclooxygenase cloning in dogfish shark, Squalus acanthias, and its role in rectal gland Cl secretion. | American journal of physiology. Regulatory, integrative and comparative physiology 20020901 |
| COX-1 and COX-2 contributions to basal and IL-1 beta-stimulated prostanoid synthesis in human neonatal cerebral microvascular endothelial cells. | Pediatric research 20020901 |
| Human fallopian tubes express prostacyclin (PGI) synthase and cyclooxygenases and synthesize abundant PGI. | The Journal of clinical endocrinology and metabolism 20020901 |
| Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats. | Arteriosclerosis, thrombosis, and vascular biology 20020901 |
| Effect of constitutive- and inducible-cyclooxygenase in the carbachol-induced pituitary-adrenocortical response during social stress. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20020901 |
| Pro-inflammatory effect of freshly solubilized beta-amyloid peptides in the brain. | Prostaglandins & other lipid mediators 20020901 |
| COX-2 selective inhibition reverses the trophic properties of gastrin in colorectal cancer. | British journal of cancer 20020827 |
| Cyclooxygenase-2 modulates brain inflammation-related gene expression in central nervous system radiation injury. | Brain research. Molecular brain research 20020815 |
| Involvement of 85-kd cytosolic phospholipase A(2) and cyclooxygenase-2 in the proliferation of human cholangiocarcinoma cells. | Hepatology (Baltimore, Md.) 20020801 |
| Cyclooxygenase-2 inhibitor induces operational tolerance to fully allogenic cardiac grafts. | Transplantation proceedings 20020801 |
| The skin fungus-induced Th1- and Th2-related cytokine, chemokine and prostaglandin E2 production in peripheral blood mononuclear cells from patients with atopic dermatitis and psoriasis vulgaris. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20020801 |
| Relationship between NOC/oFQ, dynorphin, and COX-2 activation in impaired NMDA cerebrovasodilation after brain injury. | Journal of neurotrauma 20020801 |
| Cyclooxygenase-2 inhibitor treatment enhances photodynamic therapy-mediated tumor response. | Cancer research 20020715 |
| Cyclooxygenase-2 products compensate for inhibition of nitric oxide regulation of renal perfusion. | American journal of physiology. Renal physiology 20020701 |
| Nonsteroidal anti-inflammatory drugs induce apoptosis in association with activation of peroxisome proliferator-activated receptor gamma in rheumatoid synovial cells. | The Journal of pharmacology and experimental therapeutics 20020701 |
| Study of the role of leukotriene B()4 in abnormal function of human subchondral osteoarthritis osteoblasts: effects of cyclooxygenase and/or 5-lipoxygenase inhibition. | Arthritis and rheumatism 20020701 |
| Dopamine D(2) receptor-induced COX-2-mediated production of prostaglandin E(2) in D(2)-transfected Chinese hamster ovary cells without simultaneous administration of a Ca(2+)-mobilizing agent. | Biochemical pharmacology 20020615 |
| NS-398, a selective cyclooxygenase 2 inhibitor, inhibited cell growth and induced cell cycle arrest in human hepatocellular carcinoma cell lines. | International journal of cancer 20020610 |
| Regulation and function of COX-2 gene expression in isolated gastric parietal cells. | American journal of physiology. Gastrointestinal and liver physiology 20020601 |
| Induction of MnSOD gene by arachidonic acid is mediated by reactive oxygen species and p38 MAPK signaling pathway in human HepG2 hepatoma cells. | Free radical biology & medicine 20020601 |
| Cyclooxygenase-2 regulates prostaglandin E2 signaling in hippocampal long-term synaptic plasticity. | Journal of neurophysiology 20020601 |
| Effects of TNFalpha and prostaglandin E2 on the expression of MMPs in human periodontal ligament fibroblasts. | Journal of periodontal research 20020601 |
| Role for both spinal cord COX-1 and COX-2 in maintenance of mechanical hypersensitivity following peripheral nerve injury. | Brain research 20020524 |
| The MEK/ERK pathway mediates COX-2-selective NSAID-induced apoptosis and induced COX-2 protein expression in colorectal carcinoma cells. | International journal of cancer 20020520 |
| NSAID inhibition of RGM1 gastric monolayer wound re-epithelialization: comparison of selective Cox-2 versus non-selective Cox inhibitors. | Life sciences 20020510 |
| Effect of non-steroidal anti-inflammatory drugs on colon carcinoma Caco-2 cell responsiveness to topoisomerase inhibitor drugs. | British journal of cancer 20020506 |
| Recovery of ischaemic injured porcine ileum: evidence for a contributory role of COX-1 and COX-2. | Gut 20020501 |
| Hyaluronan increases glomerular cyclooxygenase-2 protein expression in a p38 MAP-kinase-dependent process. | Kidney international 20020501 |
| Aspirin and NS-398 inhibit hepatocyte growth factor-induced invasiveness of human hepatoma cells. | Hepatology (Baltimore, Md.) 20020501 |
| Group IB secretory phospholipase A2 induces neuronal cell death via apoptosis. | Journal of neurochemistry 20020501 |
| Cyclooxygenase-2 is induced in monocytes by peroxisome proliferator activated receptor gamma and oxidized alkyl phospholipids from oxidized low density lipoprotein. | The Journal of biological chemistry 20020412 |
| Inhibitor of cyclooxygenase-2 induces cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin dependent kinase inhibitor p21. | British journal of cancer 20020408 |
| Enteroinvasive bacteria alter barrier and transport properties of human intestinal epithelium: role of iNOS and COX-2. | Gastroenterology 20020401 |
| Prostaglandin E2 down-regulates viable Bacille Calmette-Guérin-induced macrophage cytotoxicity against murine bladder cancer cell MBT-2 in vitro. | Clinical and experimental immunology 20020401 |
| Effects of Ginkgetin from Ginkgo biloba Leaves on cyclooxygenases and in vivo skin inflammation. | Planta medica 20020401 |
| Early vascular permeability in murine experimental peritonitis is co-mediated by resident peritoneal macrophages and mast cells: crucial involvement of macrophage-derived cysteinyl-leukotrienes. | Inflammation 20020401 |
| Ischemia/reperfusion-induced increase in the hepatic level of prostacyclin is mainly mediated by activation of capsaicin-sensitive sensory neurons in rats. | The Journal of laboratory and clinical medicine 20020401 |
| Cyclooxygenase-2 overexpression inhibits platelet-derived growth factor-induced mesangial cell proliferation through induction of the tumor suppressor gene p53 and the cyclin-dependent kinase inhibitors p21waf-1/cip-1 and p27kip-1. | The Journal of biological chemistry 20020322 |
| Synthesis and activity of a new methoxytetrahydropyran derivative as dual cyclooxygenase-2/5-lipoxygenase inhibitor. | Bioorganic & medicinal chemistry letters 20020311 |
| The cyclooxygenase system participates in functional mdr1b overexpression in primary rat hepatocyte cultures. | Hepatology (Baltimore, Md.) 20020301 |
| Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2. | Hypertension (Dallas, Tex. : 1979) 20020301 |
| Dihydrotestosterone (DHT) modulates the ability of NSAIDs to induce apoptosis of prostate cancer cells. | Cancer chemotherapy and pharmacology 20020301 |
| [The effects of butyrates and non-steroidal anti-inflammatory agents on HT-29 colonic carcinoma cells]. | Zhonghua nei ke za zhi 20020301 |
| Amide derivatives of meclofenamic acid as selective cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry letters 20020225 |
| GATA-6 transcriptional regulation of 15-lipoxygenase-1 during NSAID-induced apoptosis in colorectal cancer cells. | Cancer research 20020215 |
| von Hippel Lindau tumor suppressor and HIF-1alpha: new targets of NSAIDs inhibition of hypoxia-induced angiogenesis. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020201 |
| Cyclooxygenase 2-mediated suppression of macrophage interleukin-12 production after thermal injury. | American journal of physiology. Cell physiology 20020201 |
| Regulation of prostaglandin endoperoxide synthase-2 and IL-6 expression in mouse bone marrow-derived mast cells by exogenous but not endogenous prostanoids. | Journal of immunology (Baltimore, Md. : 1950) 20020201 |
| Cyclooxygenase-2 regulates apoptosis in rat epididymis through prostaglandin D2. | Biology of reproduction 20020201 |
| Nimesulide, a preferential cyclooxygenase 2 inhibitor, suppresses peroxisome proliferator-activated receptor induction of cyclooxygenase 2 gene expression in human synovial fibroblasts: evidence for receptor antagonism. | Arthritis and rheumatism 20020201 |
| Interaction of cyclooxygenase-2 inhibitors and salicylate in gastric mucosal damage. | European journal of pharmacology 20020102 |
| Indomethacin induces differential expression of beta-catenin, gamma-catenin and T-cell factor target genes in human colorectal cancer cells. | Carcinogenesis 20020101 |
| Multiple mechanisms of vascular smooth muscle relaxation by the activation of proteinase-activated receptor 2 in mouse mesenteric arterioles. | British journal of pharmacology 20020101 |
| Effects of nonsteroidal anti-inflammatory agents (NSAIDs) on ovarian carcinoma cell lines: preclinical evaluation of NSAIDs as chemopreventive agents. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020101 |
| Disparate effects of non-steroidal anti-inflammatory drugs on apoptosis in guinea-pig gastric mucous cells: inhibition of basal apoptosis by diclofenac. | British journal of pharmacology 20020101 |
| Molecular modelling of the differential interaction between several non-steroidal anti-inflammatory drugs and human prostaglandin endoperoxide H synthase-2 (h-PGHS-2). | Journal of molecular graphics & modelling 20020101 |
| Post-training cyclooxygenase-2 (COX-2) inhibition impairs memory consolidation. | Learning & memory (Cold Spring Harbor, N.Y.) 20020101 |
| Irritant-induced cyclooxygenase-2 is involved in the defense mechanism of the gastric mucosa in mice. | Journal of gastroenterology 20020101 |
| Effects of cyclooxygenase-2 inhibitor NS-398 on APC and c-myc expression in rat colon carcinogenesis induced by azoxymethane. | Journal of gastroenterology 20020101 |
| Increased cyclooxygenase-2 expression in human squamous cell carcinomas of the head and neck and inhibition of proliferation by nonsteroidal anti-inflammatory drugs. | Anticancer research 20020101 |
| Tyrphostins inhibit lipopolysaccharide induced preterm labor in mice. | Journal of perinatal medicine 20020101 |
| Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity. | Neurobiology of aging 20020101 |
| Requirement of cyclooxygenase-2 expression and prostaglandins for human prostate cancer cell invasion. | Clinical & experimental metastasis 20020101 |
| Participation of cytosolic phospholipase A2 in eicosanoid generation by mouse bone marrow-derived mast cells. | Advances in experimental medicine and biology 20020101 |
| Do leukotrienes increase cell viability in human intestinal epithelial cells? | Advances in experimental medicine and biology 20020101 |
| Cyclooxygenase-2 inhibitor NS398 preserves neuronal function after hypoxia/ischemia in piglets. | Neuroreport 20011221 |
| Constitutive expression of the cyclooxygenase-2 gene in T-cell lines infected with human T cell leukemia virus type I. | International journal of cancer 20011215 |
| The COX-2 inhibitor NS-398 causes T-cell developmental disruptions independent of COX-2 enzyme inhibition. | Cellular immunology 20011215 |
| Sodium salicylate enhances the expression of cyclooxygenase-2 in endotoxin-stimulated human mononuclear cells. | European journal of pharmacology 20011214 |
| Evidence for the expression of cyclooxygenase-2 enzyme in periodontitis. | Life sciences 20011207 |
| Cyclooxygenase-2-mediated regulation of Kupffer cell interleukin-6 production following trauma-hemorrhage and subsequent sepsis. | Shock (Augusta, Ga.) 20011201 |
| Effect of social stress on COX-1 and COX-2-induced alterations in the adrenergic agonists-evoked hypothalamic-pituitary-adrenal responses. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20011201 |
| Estimation of acute flurbiprofen and ketoprofen toxicity in rat gastric mucosa at therapy-relevant doses. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20011201 |
| COX-2 specific inhibitor, NS-398, increases macrophage migration inhibitory factor expression and induces neuroendocrine differentiation in C4-2b prostate cancer cells. | Molecular medicine (Cambridge, Mass.) 20011201 |
| [Effects of cyclooxygenase-2 on formation and healing of acetic acid-induced gastric ulcer in rats]. | Zhonghua yi xue za zhi 20011125 |
| Inhibition of angiogenesis by humulone, a bitter acid from beer hop. | Biochemical and biophysical research communications 20011123 |
| Non-steroidal anti-inflammatory drugs inhibit matrix metalloproteinase-2 expression via repression of transcription in lung cancer cells. | FEBS letters 20011123 |
| Role of cyclopentenone prostaglandins in rat carrageenin pleurisy. | FEBS letters 20011109 |
| MAPK (ERK2) kinase--a key target for NSAIDs-induced inhibition of gastric cancer cell proliferation and growth. | Life sciences 20011109 |
| Nonsteroidal anti-inflammatory drugs inhibit re-epithelialization of wounded gastric monolayers by interfering with actin, Src, FAK, and tensin signaling. | Life sciences 20011109 |
| The role of cellular migration in the repair process of gastric epithelial cells. | Life sciences 20011109 |
| Human airway smooth muscle cells secrete vascular endothelial growth factor: up-regulation by bradykinin via a protein kinase C and prostanoid-dependent mechanism. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101 |
| Prostanoids in the preoptic hypothalamus mediate systemic lipopolysaccharide-induced hyperalgesia in rats. | Brain research 20011019 |
| CaR-mediated COX-2 expression in primary cultured mTAL cells. | American journal of physiology. Renal physiology 20011001 |
| Cyclooxygenase-2 inhibitor ns-398 protects neuronal cultures from lipopolysaccharide-induced neurotoxicity. | Stroke 20011001 |
| A selective cyclooxygenase-2 inhibitor, NS-398, enhances the effect of radiation in vitro and in vivo preferentially on the cells that express cyclooxygenase-2. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011001 |
| Nitric oxide (NO) modulation of PAF-induced cardiopulmonary action: interaction between NO synthase and cyclo-oxygenase-2 pathways. | British journal of pharmacology 20011001 |
| Inhibition of leukocyte functions by the alkaloid isaindigotone from Isatis indigotica and some new synthetic derivatives. | Journal of natural products 20011001 |
| High NaCl intake decreases both flow-induced dilation and pressure-induced myogenic tone in resistance arteries from normotensive rats: involvement of cyclooxygenase-2. | Pharmacology & toxicology 20011001 |
| Increased cyclooxygenase-2 (cox-2) expression and activity in a murine model of metastatic breast cancer. | International journal of cancer 20010901 |
| Selective inhibition of COX-2 improves early survival in murine endotoxemia but not in bacterial peritonitis. | American journal of physiology. Lung cellular and molecular physiology 20010901 |
| Cell cycle effects of nonsteroidal anti-inflammatory drugs and enhanced growth inhibition in combination with gemcitabine in pancreatic carcinoma cells. | The Journal of pharmacology and experimental therapeutics 20010901 |
| Selected contribution: synergism between TNF-alpha and IL-1 beta in airway smooth muscle cells: implications for beta-adrenergic responsiveness. | Journal of applied physiology (Bethesda, Md. : 1985) 20010901 |
| PGE2 suppresses intestinal T cell function in thermal injury: a cause of enhanced bacterial translocation. | Shock (Augusta, Ga.) 20010901 |
| NSAIDs inhibit alpha V beta 3 integrin-mediated and Cdc42/Rac-dependent endothelial-cell spreading, migration and angiogenesis. | Nature medicine 20010901 |
| Interleukin-1, tumor necrosis factor alpha, and interleukin-17 synergistically up-regulate nitric oxide and prostaglandin E2 production in explants of human osteoarthritic knee menisci. | Arthritis and rheumatism 20010901 |
| Cyclooxygenase inhibitors retard murine mammary tumor progression by reducing tumor cell migration, invasiveness and angiogenesis. | International journal of cancer 20010815 |
| Inhibition of cyclooxygenase-2 aggravates doxorubicin-mediated cardiac injury in vivo. | The Journal of clinical investigation 20010815 |
| Key role for constitutive cyclooxygenase-2 of MDCK cells in basal signaling and response to released ATP. | American journal of physiology. Cell physiology 20010801 |
| Cyclooxygenase-2 does not mediate late preconditioning induced by activation of adenosine A1 or A3 receptors. | American journal of physiology. Heart and circulatory physiology 20010801 |
| Stimulation of leptin release by arachidonic acid and prostaglandin E(2) in adipose tissue from obese humans. | Metabolism: clinical and experimental 20010801 |
| Prostaglandin E2 receptors EP2 and EP4 are down-regulated in human mononuclear cells after injury. | Surgery 20010801 |
| Inhibitors of cyclooxygenase-2 (COX-2) suppressed the proliferation and differentiation of human leukaemia cell lines. | European journal of cancer (Oxford, England : 1990) 20010801 |
| Corneal stimulation of MMP-1, -9 and uPA by platelet-activating factor is mediated by cyclooxygenase-2 metabolites. | Current eye research 20010801 |
| Detection of differentially expressed genes in human colon carcinoma cells treated with a selective COX-2 inhibitor. | Oncogene 20010727 |
| Induction of apoptosis by cyclo-oxygenase-2 inhibitor NS398 through a cytochrome C-dependent pathway in esophageal cancer cells. | International journal of cancer 20010715 |
| Effect of COX-2 inhibitor NS-398 on expression of PGE2 receptor subtypes in M-1 mouse CCD cells. | American journal of physiology. Renal physiology 20010701 |
| COX-2 expression and cell cycle progression in human fibroblasts. | American journal of physiology. Cell physiology 20010701 |
| Role of prostaglandins in the suppression of apoptosis in hen granulosa cells by transforming growth factor alpha. | Reproduction (Cambridge, England) 20010701 |
| Generation of 8-epi-prostaglandin F(2alpha) in isolated rat kidney glomeruli by a radical-independent mechanism. | British journal of pharmacology 20010701 |
| Induction of apoptosis by cyclooxygenase-2 inhibitors in prostate cancer cell lines. | International journal of urology : official journal of the Japanese Urological Association 20010701 |
| Obesity is induced in mice heterozygous for cyclooxygenase-2. | Prostaglandins & other lipid mediators 20010701 |
| Modulation of haem oxygenase-1 expression by nitric oxide and leukotrienes in zymosan-activated macrophages. | British journal of pharmacology 20010701 |
| Nonsteroidal anti-inflammatory drugs induce apoptosis in esophageal cancer cells by restoring 15-lipoxygenase-1 expression. | Cancer research 20010615 |
| Both cyclooxygenase-1 and cyclooxygenase-2 mediate osteoblast response to titanium surface roughness. | Journal of biomedical materials research 20010605 |
| Cholera toxin induces prostaglandin synthesis via post-transcriptional activation of cyclooxygenase-2 in the rat jejunum. | The Journal of pharmacology and experimental therapeutics 20010601 |
| Tumor necrosis factor-alpha induces cyclooxygenase-2 expression and prostaglandin release in brain microvessel endothelial cells. | The Journal of pharmacology and experimental therapeutics 20010601 |
| Adaptive gastric cytoprotection is mediated by prostaglandin EP1 receptors: a study using rats and knockout mice. | The Journal of pharmacology and experimental therapeutics 20010601 |
| NS-398 treatment after trauma modifies NF-kappaB activation and improves survival. | The Journal of surgical research 20010601 |
| Temporal variation in endotoxin-induced vascular hyporeactivity in a rat mesenteric artery organ culture model. | British journal of pharmacology 20010601 |
| Classic NSAID and selective cyclooxygenase (COX)-1 and COX-2 inhibitors in healing of chronic gastric ulcers. | Microscopy research and technique 20010601 |
| Topical bicuculline to the rat spinal cord induces highly localized allodynia that is mediated by spinal prostaglandins. | Pain 20010601 |
| Enhanced cyclooxygenase-2 mRNA expression in human gingival fibroblasts induced by cell contact with human lymphocytes. | European journal of oral sciences 20010601 |
| Platelet activating factor increases ciliary activity in the hamster oviduct through epithelial production of prostaglandin E2. | Pflugers Archiv : European journal of physiology 20010601 |
| [Study on the effect of COX-2's selective inhibitor on human colorectal adenoma cells proliferation]. | Zhonghua nei ke za zhi 20010601 |
| Inducible cyclooxygenase-2 expression after experimental intracerebral hemorrhage. | Brain research 20010518 |
| COX-2-dependent delayed dilatation of cerebral arterioles in response to bradykinin. | American journal of physiology. Heart and circulatory physiology 20010501 |
| Cytochrome P450 metabolites of arachidonic acid but not cyclooxygenase-2 metabolites contribute to the pulmonary vascular hyporeactivity in rats with acute Pseudomonas pneumonia. | The Journal of pharmacology and experimental therapeutics 20010501 |
| Role of renocortical cyclooxygenase-2 for renal vascular resistance and macula densa control of renin secretion. | Journal of the American Society of Nephrology : JASN 20010501 |
| Expression of cyclooxygenase-2 (COX-2) in hepatocellular carcinoma and growth inhibition of hepatoma cell lines by a COX-2 inhibitor, NS-398. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010501 |
| Stimulation of cyclooxygenase-2-activity by nitric oxide-derived species in rat chondrocyte: lack of contribution to loss of cartilage anabolism. | Biochemical pharmacology 20010415 |
| Dendritic cells issued in vitro from bone marrow produce PGE(2) that contributes to the immunomodulation induced by antigen-presenting cells. | Cellular immunology 20010410 |
| Induction of apoptosis in colon cancer cells by cyclooxygenase-2 inhibitor NS398 through a cytochrome c-dependent pathway. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010401 |
| Effect of hypoxia, oxidative stress and lipopolysaccharides on the release of prostaglandins and cytokines from human term placental explants. | Placenta 20010401 |
| Involvement of cyclooxygenase-2 in serum-induced prostaglandin production by human oral gingival epithelial cells. | Journal of periodontal research 20010401 |
| Reduction of pathological and behavioral deficits following spinal cord contusion injury with the selective cyclooxygenase-2 inhibitor NS-398. | Journal of neurotrauma 20010401 |
| Cyclooxygenase-2 is upregulated in inflamed gingival tissues. | Journal of periodontology 20010401 |
| Solid-phase synthesis and inhibitory effects of some pyrido[1,2-c]pyrimidine derivatives on leukocyte formations and experimental inflammation. | Journal of medicinal chemistry 20010315 |
| The 'in vivo' and 'ex vivo' roles of cylcooxygenase-2, nuclear factor-kappaB and protein kinases pathways in the up-regulation of B1 receptor-mediated contraction of the rabbit aorta. | Regulatory peptides 20010302 |
| Dose-dependent modulation of apoptosis and cyclooxygenase-2 expression in human 1547 osteosarcoma cells by NS-398, a selective cyclooxygenase-2 inhibitor. | International journal of oncology 20010301 |
| Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells. | Hepatology (Baltimore, Md.) 20010301 |
| Differential effects of ethanol on the expression of cyclo-oxygenase in cultured cortical astrocytes and neurons. | Journal of neurochemistry 20010301 |
| Disturbance of peristalsis in the guinea-pig isolated small intestine by indomethacin, but not cyclo-oxygenase isoform-selective inhibitors. | British journal of pharmacology 20010301 |
| Nuclear factor-kappaB regulates cyclooxygenase-2 expression and cell proliferation in human gastric cancer cells. | Laboratory investigation; a journal of technical methods and pathology 20010301 |
| Involvement of cyclooxygenase-derived prostaglandin E2 and nitric oxide in the protection of rat pancreas afforded by low dose of lipopolysaccharide. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20010301 |
| Stimulative effect of cadmium on prostaglandin E2 production in primary mouse osteoblastic cells. | Calcified tissue international 20010301 |
| Upregulation of angiotensin-converting enzyme by vascular endothelial growth factor. | American journal of physiology. Heart and circulatory physiology 20010201 |
| Inhibition of COX in ocular tissues: an in vitro model to identify selective COX-2 inhibitors. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010201 |
| Prostaglandin H synthase-2 inhibitors interfere with prostaglandin H synthase-1 inhibition by nonsteroidal anti-inflammatory drugs. | European journal of pharmacology 20010119 |
| Specific inhibition of cyclooxygenase-2 results in inhibition of proliferation of oral cancer cell lines via suppression of prostaglandin E2 production. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010101 |
| Effects of indomethacin, NS-398 (a selective prostaglandin H synthase-2 inhibitor) and protein synthesis inhibitors on prostaglandin production by the guinea-pig placenta. | Prostaglandins, leukotrienes, and essential fatty acids 20010101 |
| Expression of cyclooxygenase 2 in human malignant melanoma. | Cancer research 20010101 |
| Piroxicam and NS-398 rescue neurones from hypoxia/reoxygenation damage by a mechanism independent of cyclo-oxygenase inhibition. | Journal of neurochemistry 20010101 |
| Effects of COX-1 and COX-2 inhibitors on eicosanoid biosynthesis and the release of substance P from the guinea-pig isolated perfused lung. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20010101 |
| Differential regulation of interleukin-1 beta-induced cyclooxygenase-2 gene expression by nimesulide in human synovial fibroblasts. | Clinical and experimental rheumatology 20010101 |
| Non-steroidal anti-inflammatory drugs protect against chondrocyte apoptotic death. | Clinical and experimental rheumatology 20010101 |
| Apoptosis signaling pathways mediated by cyclooxygenase-2 inhibitors in prostate cancer cells. | Advances in enzyme regulation 20010101 |
| Effects of 1alpha,25-(OH)(2)D(3) on rat growth zone chondrocytes are mediated via cyclooxygenase-1 and phospholipase A(2). | Journal of cellular biochemistry. Supplement 20010101 |
| The comparative release of FGF1 by hypoxia and temperature stress. | Growth factors (Chur, Switzerland) 20010101 |
| NSAIDs inhibit the activation of egr-1 gene in microvascular endothelial cells. A key to inhibition of angiogenesis? | Journal of physiology, Paris 20010101 |
| Cyclooxygenase-2 level and culture conditions influence NS398-induced apoptosis and caspase activation in lung cancer cells. | Oncology reports 20010101 |
| Sepsis-induced alteration in T-cell Ca(2+) signaling in neonatal rats. | Biology of the neonate 20010101 |
| Synovial cells from a patient with rheumatoid arthritis produce osteoclastogenesis inhibitory factor/osteoprotegerin: reciprocal regulation of the production by inflammatory cytokines and basic fibroblast growth factor. | Journal of bone and mineral metabolism 20010101 |
| Cyclooxygenase-2 expression in lipopolysaccharide-stimulated human monocytes is modulated by cyclic AMP, prostaglandin E(2), and nonsteroidal anti-inflammatory drugs. | Biochemical and biophysical research communications 20001130 |
| Selective inhibition of cyclooxygenase-2 suppresses growth and induces apoptosis in human esophageal adenocarcinoma cells. | Cancer research 20001015 |
| Endotoxin augments cerebral hyperemic response to halothane by inducing nitric oxide synthase and cyclooxygenase. | Anesthesia and analgesia 20001001 |
| Regulation of leptin release and lipolysis by PGE2 in rat adipose tissue. | Prostaglandins & other lipid mediators 20001001 |
| Induction of cyclooxygenase-2 by overexpression of the human catalase gene in cerebral microvascular endothelial cells. | Journal of neurochemistry 20000801 |
| 15-LOX-1: a novel molecular target of nonsteroidal anti-inflammatory drug-induced apoptosis in colorectal cancer cells. | Journal of the National Cancer Institute 20000719 |
| Class A scavenger receptor up-regulation in smooth muscle cells by oxidized low density lipoprotein. Enhancement by calcium flux and concurrent cyclooxygenase-2 up-regulation. | The Journal of biological chemistry 20000609 |
| Par-4, a proapoptotic gene, is regulated by NSAIDs in human colon carcinoma cells. | Gastroenterology 20000601 |
| Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (gamma-sultam) skeleton: cytokine suppressive dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase. | Journal of medicinal chemistry 20000518 |
| The effect of NSAIDs and a COX-2 specific inhibitor on Helicobacter pylori-induced PGE2 and HGF in human gastric fibroblasts. | Alimentary pharmacology & therapeutics 20000401 |
| The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models. | European journal of pharmacology 20000310 |
| 24R,25-(OH)(2)D(3) mediates its membrane receptor-dependent effects on protein kinase C and alkaline phosphatase via phospholipase A(2) and cyclooxygenase-1 but not cyclooxygenase-2 in growth plate chondrocytes. | Journal of cellular physiology 20000301 |
| Induction of cyclooxygenase expression and enhancement of malignant cell transformation by 2,3,7,8-tetrachlorodibenzo-p-dioxin. | Carcinogenesis 20000101 |
| Expression of cyclooxygenase (COX)-1 and COX-2 in adaptive cytoprotection induced by mild stress. | Journal of physiology, Paris 20000101 |
| Selective cyclo-oxygenase-2 inhibitors aggravate ischaemia-reperfusion injury in the rat stomach. | British journal of pharmacology 19991201 |
| Endogenous prostaglandin formation in the field-stimulated guinea-pig vas deferens: comparison of the inhibitory effects of indomethacin and NS-398. | Prostaglandins, leukotrienes, and essential fatty acids 19991201 |
| Role of prostaglandins generated by cyclooxygenase-1 and cyclooxygenase-2 in healing of ischemia-reperfusion-induced gastric lesions. | European journal of pharmacology 19991126 |
| Cyclooxygenase-2 selective inhibitors aggravate kainic acid induced seizure and neuronal cell death in the hippocampus. | Brain research 19991002 |
| Increased cyclooxygenase-2 expression in human pancreatic carcinomas and cell lines: growth inhibition by nonsteroidal anti-inflammatory drugs. | Cancer research 19990901 |
| IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. | The Journal of clinical investigation 19990501 |
| Inhibition of cyclooxygenase-2 expression by 4-trifluoromethyl derivatives of salicylate, triflusal, and its deacetylated metabolite, 2-hydroxy-4-trifluoromethylbenzoic acid. | Molecular pharmacology 19990401 |
| Structure-based design of COX-2 selectivity into flurbiprofen. | Bioorganic & medicinal chemistry letters 19990208 |
| Resveratrol inhibits cyclooxygenase-2 transcription and activity in phorbol ester-treated human mammary epithelial cells. | The Journal of biological chemistry 19980821 |
| Aspirin and salicylate induce apoptosis and activation of caspases in B-cell chronic lymphocytic leukemia cells. | Blood 19980815 |
| Tumour necrosis factor-alpha-dependent regulation of prostaglandin endoperoxide synthase-2. | Cytokine 19980301 |
| Differential effects of nonsteroidal anti-inflammatory drugs on constitutive and inducible prostaglandin G/H synthase in cultured bone cells. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 19970801 |
| Induction of cyclooxygenase 2 in gastric mucosal lesions and its inhibition by the specific antagonist delays healing in mice. | Gastroenterology 19970201 |
| Dual inhibition of nitric oxide and prostaglandin production contributes to the antiinflammatory properties of nitric oxide synthase inhibitors. | The Journal of clinical investigation 19950701 |
| NS-398, a novel non-steroidal anti-inflammatory drug with potent analgesic and antipyretic effects, which causes minimal stomach lesions. | General pharmacology 19930101 |
| [Myocardial infarct after adriamycin]. | Deutsche medizinische Wochenschrift (1946) 19840427 |