Home Nitros N-Methyl-N-nitrosourea

N-Methyl-N-nitrosourea

CAS No.:
684-93-5
Catalog Number:
AG0035EI
Molecular Formula:
C2H5N3O2
Molecular Weight:
103.0800
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Purity
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Product Description
Catalog Number:
AG0035EI
Chemical Name:
N-Methyl-N-nitrosourea
CAS Number:
684-93-5
Molecular Formula:
C2H5N3O2
Molecular Weight:
103.0800
IUPAC Name:
1-methyl-1-nitrosourea
InChI:
InChI=1S/C2H5N3O2/c1-5(4-7)2(3)6/h1H3,(H2,3,6)
InChI Key:
ZRKWMRDKSOPRRS-UHFFFAOYSA-N
SMILES:
O=NN(C(=O)N)C
EC Number:
211-678-4
UNII:
W8KW4E3XSU
NSC Number:
23909
Properties
Complexity:
90.9  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
103.038g/mol
Formal Charge:
0
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
103.081g/mol
Monoisotopic Mass:
103.038g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
75.8A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0
Literature
Title Journal
A novel, integrated in vitro carcinogenicity test to identify genotoxic and non-genotoxic carcinogens using human lymphoblastoid cells. Archives of toxicology 20180101
Differential effects between developmental and postpubertal exposure to N-methyl-N-nitrosourea on progenitor cell proliferation of rat hippocampal neurogenesis in relation to COX2 expression in granule cells. Toxicology 20170815
Lung Tumor Induction by 26-week Dermal Application of 1,2-Dichloroethane in CB6F1-Tg rasH2 Mice. Toxicologic pathology 20170401
Twenty-six-week oral carcinogenicity study of 3-monochloropropane-1,2-diol in CB6F1-rasH2 transgenic mice. Archives of toxicology 20170101
Alternative Multiorgan Initiation-Promotion Assay for Chemical Carcinogenesis in the Wistar Rat. Toxicologic pathology 20161201
The PIGRET assay, a method for measuring Pig-a gene mutation in reticulocytes, is reliable as a short-term in vivo genotoxicity test: Summary of the MMS/JEMS-collaborative study across 16 laboratories using 24 chemicals. Mutation research 20161115
Epithelial-mesenchymal transition and FOXA genes during tobacco smoke carcinogen induced transformation of human bronchial epithelial cells. Toxicology in vitro : an international journal published in association with BIBRA 20160901
A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens. Archives of toxicology 20151201
Differential DNA methylation profile of key genes in malignant prostate epithelial cells transformed by inorganic arsenic or cadmium. Toxicology and applied pharmacology 20150801
Quercetin, a natural dietary flavonoid, acts as a chemopreventive agent against prostate cancer in an in vivo model by inhibiting the EGFR signaling pathway. Food & function 20141001
N-methyl-N-nitrosourea during late gestation results in concomitant but reversible progenitor cell reduction and delayed neurogenesis in the hippocampus of rats. Toxicology letters 20140502
Maternal single injection of N-methyl-N-nitrosourea to cause microcephaly in offspring induces transient aberration of hippocampal neurogenesis in mice. Toxicology letters 20140407
Influence of DNA repair on nonlinear dose-responses for mutation. Toxicological sciences : an official journal of the Society of Toxicology 20130301
Rosiglitazone shows partial oncostatic effect in rat mammary carcinogenesis. Neoplasma 20130101
Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis. PloS one 20130101
Efficient monitoring of in vivo pig-a gene mutation and chromosomal damage: summary of 7 published studies and results from 11 new reference compounds. Toxicological sciences : an official journal of the Society of Toxicology 20121201
Intraductal administration of a polymeric nanoparticle formulation of curcumin (NanoCurc) significantly attenuates incidence of mammary tumors in a rodent chemical carcinogenesis model: Implications for breast cancer chemoprevention in at-risk populations. Carcinogenesis 20121101
Protective effect of lactofermented beetroot juice against aberrant crypt foci formation and genotoxicity of fecal water in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20120901
N-methyl N-nitrosourea induced functional and structural alterations in mice brain-role of curcumin. Neurotoxicity research 20120801
Identification of a molecular signature underlying inhibition of mammary carcinoma growth by dietary N-3 fatty acids. Cancer research 20120801
Tumor and non-tumor tissues differential oxidative stress response to supplemental DHA and chemotherapy in rats. Cancer chemotherapy and pharmacology 20120701
Mammary cancer promotion by ovarian hormones involves IGFR/AKT/mTOR signaling. Steroids 20120601
Pol kappa partially rescues MMR-dependent cytotoxicity of O6-methylguanine. DNA repair 20120601
Anti-tumor effects of a novel retinoic acid metabolism blocking agent VN/14-1 in the N-methyl-N-nitrosourea-induced rat mammary carcinoma model and its effects on the uterus. Breast cancer research and treatment 20120501
N-methyl N-nitroso Urea induced altered DNA structure initiate hepatocarcinogenesis. Preventive medicine 20120501
Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers. Oncology reports 20120501
Exploring molecular genetics of bladder cancer: lessons learned from mouse models. Disease models & mechanisms 20120501
Maternal high-methyl diet suppresses mammary carcinogenesis in female rat offspring. Carcinogenesis 20120501
Gene-TEQ--a standardized comparative assessment of effects in the comet assay using genotoxicity equivalents. Journal of environmental monitoring : JEM 20120501
In vivo interactions between ionizing radiation, inflammation and chemical carcinogens identified by increased DNA damage responses. Radiation research 20120501
Anthocyanins from the seed coat of black soybean reduce retinal degeneration induced by N-methyl-N-nitrosourea. Experimental eye research 20120401
Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3. Aging 20120401
Alterations in c-Src/HER1 and estrogen receptor α signaling pathways in mammary gland and tumors of hexachlorobenzene-treated rats. Toxicology 20120311
A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20120301
Disruption of Klf4 in villin-positive gastric progenitor cells promotes formation and progression of tumors of the antrum in mice. Gastroenterology 20120301
Activation of AMP-activated protein kinase by MAPO1 and FLCN induces apoptosis triggered by alkylated base mismatch in DNA. DNA repair 20120301
Effects of energy restriction and wheel running on mammary carcinogenesis and host systemic factors in a rat model. Cancer prevention research (Philadelphia, Pa.) 20120301
A comparison of cell-collecting methods for the Comet assay in urinary bladders of rats. Mutation research 20120218
A positive feedback signaling loop between ATM and the vitamin D receptor is critical for cancer chemoprevention by vitamin D. Cancer research 20120215
High incidence of acute promyelocytic leukemia specifically induced by N-nitroso-N-methylurea (NMU) in Sprague-Dawley rats. Archives of toxicology 20120201
Modifying effects of lemongrass essential oil on specific tissue response to the carcinogen N-methyl-N-nitrosurea in female BALB/c mice. Journal of medicinal food 20120201
Anti-tumour effects of small interfering RNA targeting anion exchanger 1 in experimental gastric cancer. British journal of pharmacology 20120101
Vitamin D₃ upregulated protein 1 deficiency promotes N-methyl-N-nitrosourea and Helicobacter pylori-induced gastric carcinogenesis in mice. Gut 20120101
Microarray analysis on germfree mice elucidates the primary target of a traditional Japanese medicine juzentaihoto: acceleration of IFN-α response via affecting the ISGF3-IRF7 signaling cascade. BMC genomics 20120101
Morphology of 1-methyl-1-nitrosourea induced rat mammary tumours after treatment with precursor of phytanic acid or its combination with vitamin D analogue. Endocrine regulations 20120101
Role of oxidative stress in retinal photoreceptor cell death in N-methyl-N-nitrosourea-treated mice. Journal of pharmacological sciences 20120101
Melatonin enhanced bexarotene efficacy in experimental mammary carcinogenesis. Neoplasma 20120101
The effect of dietary zinc--and polyphenols intake on DMBA-induced mammary tumorigenesis in rats. Journal of biomedical science 20120101
BRCA1-IRIS overexpression promotes formation of aggressive breast cancers. PloS one 20120101
Human chorionic gonadotropin inhibits N-Methyl-N-nitrosourea-induced mammary carcinoma growth in female Lewis rats. In vivo (Athens, Greece) 20120101
MicroRNA-34a and microRNA-21 play roles in the chemopreventive effects of 3,6-dihydroxyflavone on 1-methyl-1-nitrosourea-induced breast carcinogenesis. Breast cancer research : BCR 20120101
[Mechanisms of radioresistance in terminally differentiated cells of mature retina]. Tsitologiia 20120101
Thyroid hormone deiodinases and cancer. Frontiers in endocrinology 20120101
Curcumin attenuates gastric cancer induced by N-methyl-N-nitrosourea and saturated sodium chloride in rats. Journal of biomedicine & biotechnology 20120101
Protection by Salvia extracts against oxidative and alkylation damage to DNA in human HCT15 and CO115 cells. Journal of toxicology and environmental health. Part A 20120101
Distinctive features of advancing breast cancer cells and interactions with surrounding stroma observed under the scanning electron microscope. Asian Pacific journal of cancer prevention : APJCP 20120101
Mouse models of Helicobacter-induced gastric cancer: use of cocarcinogens. Methods in molecular biology (Clifton, N.J.) 20120101
The identification of a novel gene, MAPO2, that is involved in the induction of apoptosis triggered by O⁶-methylguanine. PloS one 20120101
Fish oil alters tamoxifen-modulated expression of mRNAs that encode genes related to differentiation, proliferation, metastasis, and immune response in rat mammary tumors. Nutrition and cancer 20120101
[Neoplastic effect of indomethacin in N-methyl-N-nitrosourea induced mammary carcinogenesis in female rats]. Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti 20120101
Effects of Auraptene on IGF-1 Stimulated Cell Cycle Progression in the Human Breast Cancer Cell Line, MCF-7. International journal of breast cancer 20120101
Establishment of a mammary carcinoma cell line from Syrian hamsters treated with N-methyl-N-nitrosourea. Cancer letters 20111215
Time-series analysis of gene expression profiles induced by nitrosamides and nitrosamines elucidates modes of action underlying their genotoxicity in human colon cells. Toxicology letters 20111215
Metabolic effects of pioglitazone in chemically-induced mammary carcinogenesis in rats. Pathology oncology research : POR 20111201
International Pig-a gene mutation assay trial (stage III): results with N-methyl-N-nitrosourea. Environmental and molecular mutagenesis 20111201
Investigation of cell death induced by N-methyl-N-nitrosourea in cell lines of human origin and implication of RNA binding protein alterations. Anticancer research 20111201
Morphological and functional evaluation of an animal model for the retinal degeneration induced by N-methyl-N-nitrosourea. Anatomy & cell biology 20111201
Medium-term multi-organ carcinogenesis bioassay of ethyl tertiary-butyl ether in rats. Toxicology 20111118
MNU-induced mammary gland carcinogenesis: chemopreventive and therapeutic effects of vitamin D and Seocalcitol on selected regulatory vitamin D receptor pathways. Toxicology letters 20111110
Retinas of the diurnal rodent Arvicanthis ansorgei are highly resistant to experimentally induced stress and degeneration. Investigative ophthalmology & visual science 20111107
Determinants of DHA incorporation into tumor tissue during dietary DHA supplementation. Lipids 20111101
Effects of fish oil and Tamoxifen on preneoplastic lesion development and biomarkers of oxidative stress in the early stages of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. International journal of oncology 20111101
Preclinical and clinical evaluation of intraductally administered agents in early breast cancer. Science translational medicine 20111026
Toxicological characterization of N-methyl-N-nitrosourea-induced cataract in rats by LC/MS-based metabonomic analysis. Journal of applied toxicology : JAT 20111001
Mammary gland density predicts the cancer inhibitory activity of the N-3 to N-6 ratio of dietary fat. Cancer prevention research (Philadelphia, Pa.) 20111001
Genotoxicity screening via the γH2AX by flow assay. Mutation research 20111001
Effects of 5,6-benzoflavone, indole-3-carbinol (I3C) and diindolylmethane (DIM) on chemically-induced mammary carcinogenesis: is DIM a substitute for I3C? Oncology reports 20110901
Protective effect of zinc on N-methyl-N-nitrosourea and testosterone-induced prostatic intraepithelial neoplasia in the dorsolateral prostate of Sprague Dawley rats. Experimental biology and medicine (Maywood, N.J.) 20110901
Effects of short-term estrogen treatment on the progression of N-methyl-N-nitrosourea-induced premalignant mammary lesions in female Lewis rats. Medical molecular morphology 20110901
Effect of methyl methanesulfonate on hsp70 expression and tissue damage in the third instar larvae of transgenic Drosophila melanogaster (hsp70-lacZ) Bg. Interdisciplinary toxicology 20110901
Undifferentiated Sarcoma of the Salivary Gland in a Mongolian Gerbil (Meriones unguiculatus). Journal of toxicologic pathology 20110901
New allele of HvBRI1 gene encoding brassinosteroid receptor in barley. Journal of applied genetics 20110801
Correlation between high-resolution optical coherence tomography (OCT) images and histopathology in an N-methyl-N-nitrosourea-induced retinal degeneration rat model. The British journal of ophthalmology 20110801
Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate. Carcinogenesis 20110801
Lapatinib, a preventive/therapeutic agent against mammary cancer, suppresses RTK-mediated signaling through multiple signaling pathways. Cancer prevention research (Philadelphia, Pa.) 20110801
Targeting the HER/EGFR/ErbB family to prevent breast cancer. Cancer prevention research (Philadelphia, Pa.) 20110801
Potential role of melatonin in DNA damage caused by nitrosourea-induced mammary carcinogenesis. Acta histochemica 20110701
Metabolic signatures of malignant progression in prostate epithelial cells. The international journal of biochemistry & cell biology 20110701
Pre- and postpubertal irradiation induces mammary cancers with distinct expression of hormone receptors, ErbB ligands, and developmental genes in rats. Molecular carcinogenesis 20110701
Targeted deletion of GSNOR in hepatocytes of mice causes nitrosative inactivation of O6-alkylguanine-DNA alkyltransferase and increased sensitivity to genotoxic diethylnitrosamine. Carcinogenesis 20110701
Discovery of rare mutations in populations: TILLING by sequencing. Plant physiology 20110701
Hypothalamus-pituitary-thyroid axis disruption in rats with breast cancer is related to an altered endogenous oxytocin/insulin-regulated aminopeptidase (IRAP) system. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110601
Caspase-3-independent photoreceptor degeneration by N-methyl-N-nitrosourea (MNU) induces morphological and functional changes in the mouse retina. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20110601
Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract. Interdisciplinary toxicology 20110601
Sensitive DsRed fluorescence-based reporter cell systems for genotoxicity and oxidative stress assessment. Mutation research 20110510
Assessment of primary, oxidative and excision repaired DNA damage in hospital personnel handling antineoplastic drugs. Mutagenesis 20110501
Loss of Runx3 is a key event in inducing precancerous state of the stomach. Gastroenterology 20110501
Fine mapping and candidate gene analysis of dense and erect panicle 3, DEP3, which confers high grain yield in rice (Oryza sativa L.). TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20110501
Impairment of the tRNA-splicing endonuclease subunit 54 (tsen54) gene causes neurological abnormalities and larval death in zebrafish models of pontocerebellar hypoplasia. Human molecular genetics 20110415
Chemopreventive effects of zinc on prostate carcinogenesis induced by N-methyl-N-nitrosourea and testosterone in adult male Sprague-Dawley rats. Journal of cancer research and clinical oncology 20110401
Breast tumors induced by N-methyl-N-nitrosourea are damaging to bone strength, structure, and mineralization in the absence of metastasis in rats. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110401
[Anionic long circulation liposomes mediated antisense scintigraphy in tumor-bearing rats]. Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20110401
hMSH2 recruits ATR to DNA damage sites for activation during DNA damage-induced apoptosis. The Journal of biological chemistry 20110325
Chemical-induced cancer incidence and underlying mechanisms in Fen1 mutant mice. Oncogene 20110303
Trypanosoma cruzi MSH2: Functional analyses on different parasite strains provide evidences for a role on the oxidative stress response. Molecular and biochemical parasitology 20110301
Inhibition of gastric carcinogenesis by the hormone gastrin is mediated by suppression of TFF1 epigenetic silencing. Gastroenterology 20110301
CDB-4124, a progesterone receptor modulator, inhibits mammary carcinogenesis by suppressing cell proliferation and inducing apoptosis. Cancer prevention research (Philadelphia, Pa.) 20110301
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer. Disease models & mechanisms 20110301
Enhanced Urinary Bladder, Liver and Colon Carcinogenesis in Zucker Diabetic Fatty Rats in a Multiorgan Carcinogenesis Bioassay: Evidence for Mechanisms Involving Activation of PI3K Signaling and Impairment of p53 on Urinary Bladder Carcinogenesis. Journal of toxicologic pathology 20110301
Intervention of nicotine on MNU-induced bladder cancer in rats. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20110201
Abnormal Savda Munziq, an Herbal Preparation of Traditional Uighur Medicine, May Prevent 1,2-dimethylhydrazine-Induced Rat Colon Carcinogenesis. Evidence-based complementary and alternative medicine : eCAM 20110101
26-Week carcinogenicity study of di-isodecyl phthalate by dietary administration to CB6F1-rasH2 transgenic mice. Archives of toxicology 20110101
Long-term hormonal promotion overcomes genetic resistance to mammary cancer. Steroids 20110101
Endocrine disrupting chemicals modulate expression of O⁶-methylguanine DNA methyltransferase (O⁶-MGMT) gene in the hermaphroditic fish, Kryptolebias marmoratus. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20110101
Insufficient role of cell proliferation in aberrant DNA methylation induction and involvement of specific types of inflammation. Carcinogenesis 20110101
FISH in analysis of gamma ray-induced micronuclei formation in barley. Journal of applied genetics 20110101
Comprehensive profiling of zebrafish hepatic proximal promoter CpG island methylation and its modification during chemical carcinogenesis. BMC genomics 20110101
Review: Animal models of N-Methyl-N-nitrosourea-induced mammary cancer and retinal degeneration with special emphasis on therapeutic trials. In vivo (Athens, Greece) 20110101
Effects of short-term pregnancy hormone treatment against N-methyl-N-nitrosourea-induced mammary carcinomas in female Lewis rats. In vivo (Athens, Greece) 20110101
The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies. Journal of carcinogenesis 20110101
Chemically induced breast tumors in rats are detectable in early stages by contrast enhanced magnetic resonance imaging but not by changes in the acute-phase reactants in serum. International journal of molecular sciences 20110101
Metabolism, genomics, and DNA repair in the mouse aging liver. Current gerontology and geriatrics research 20110101
Tumor-associated macrophages recruit CCR6+ regulatory T cells and promote the development of colorectal cancer via enhancing CCL20 production in mice. PloS one 20110101
The comparative protective effects of ganoderma spores lipid and fish oil on N-methyl-N-nitrosourea-induced photoreceptor cell lesion in rats. Evidence-based complementary and alternative medicine : eCAM 20110101
Calpain inhibition restores basal autophagy and suppresses MNU-induced photoreceptor cell death in mice. In vivo (Athens, Greece) 20110101
The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner. PloS one 20110101
Statistical mutation calling from sequenced overlapping DNA pools in TILLING experiments. BMC bioinformatics 20110101
Metformin as an energy restriction mimetic agent for breast cancer prevention. Journal of carcinogenesis 20110101
Experimental gastric carcinogenesis in Cebus apella nonhuman primates. PloS one 20110101
The non-protein coding breast cancer susceptibility locus Mcs5a acts in a non-mammary cell-autonomous fashion through the immune system and modulates T-cell homeostasis and functions. Breast cancer research : BCR 20110101
N-Nitrosamines (15 listings): N-Nitroso-N-methylurea. Report on carcinogens : carcinogen profiles 20110101
Upstream molecular signaling pathways of p27(Kip1) expression in human breast cancer cells in vitro: differential effects of 4-hydroxytamoxifen and deficiency of either D-(+)-glucose or L-leucine. Cancer cell international 20110101
[Genoprotective activities of the oils from leaves and fruits of Fagus orientalis Lipsky]. TSitologiia i genetika 20110101
Rats: gnawing through the barriers to understanding genetic susceptibility and breast cancer. Breast cancer research : BCR 20110101
Aberrant expression and phosphorylation of 4E-BP1, a main target of mTOR signaling, in rat mammary carcinomas: an association with etiology. In vivo (Athens, Greece) 20110101
Quantification of epithelial cell differentiation in mammary glands and carcinomas from DMBA- and MNU-exposed rats. PloS one 20110101
Is there a role for carbohydrate restriction in the treatment and prevention of cancer? Nutrition & metabolism 20110101
Detection of the onset of ischemia and carcinogenesis by hypoxia-inducible transcription factor-based in vivo bioluminescence imaging. PloS one 20110101
Chemoprevention of prostate cancer: Natural compounds, antiandrogens, and antioxidants - In vivo evidence. Journal of carcinogenesis 20110101
[Influence of sodium selenite on carcinogenesis of the prostate and other organs induced by methylnitrosourea and testosterone in rats]. Voprosy onkologii 20110101
Effect of Cu supplementation on genomic instability in chemically-induced mammary carcinogenesis in the rat. Journal of biomedical science 20110101
Identification of differentially-expressed proteins between early submucosal non-invasive and invasive colorectal cancer using 2D-DIGE and mass spectrometry. International journal of immunopathology and pharmacology 20110101
Hormones and prostate carcinogenesis: Androgens and estrogens. Journal of carcinogenesis 20110101
Mutagenesis as a tool in plant genetics, functional genomics, and breeding. International journal of plant genomics 20110101
17α-ethynyl-5α-androstane-3α, 17β-diol treatment of MNU-induced mammary cancer in rats. International journal of breast cancer 20110101
Miniaturized flow cytometric in vitro micronucleus assay represents an efficient tool for comprehensively characterizing genotoxicity dose-response relationships. Mutation research 20101221
Mammary renin-angiotensin system-regulating aminopeptidase activities are modified in rats with breast cancer. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20101201
Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis. Carcinogenesis 20101201
Hypothalamic cocaine- and amphetamine-regulated transcript peptide is reduced and fails to modulate feeding behavior in rats with chemically-induced mammary carcinogenesis. Pharmacology, biochemistry, and behavior 20101201
Antimutagenic effects of lycopene and tomato purée. Journal of medicinal food 20101201
Hematopoietic proliferative lesions in the spleen of rasH2 transgenic mice treated with MNU. Toxicologic pathology 20101201
Molecular histopathology by spectrally reconstructed nonlinear interferometric vibrational imaging. Cancer research 20101201
Fetal alcohol exposure increases mammary tumor susceptibility and alters tumor phenotype in rats. Alcoholism, clinical and experimental research 20101101
Wheel running-induced changes in plasma biomarkers and carcinogenic response in the 1-methyl-1-nitrosourea-induced rat model for breast cancer. Cancer prevention research (Philadelphia, Pa.) 20101101
ABCB1/MDR1 gene polymorphisms as a prognostic factor in colorectal cancer. International journal of colorectal disease 20101001
Immune compartmentalization of T cell subsets in chemically-induced breast cancer. Scandinavian journal of immunology 20101001
Luteinizing hormone receptor deficiency increases the susceptibility to alkylating agent-induced lymphomagenesis in mice. Hormones & cancer 20101001
Cone loss is delayed relative to rod loss during induced retinal degeneration in the diurnal cone-rich rodent Arvicanthis ansorgei. Neuroscience 20100915
Pioglitazone in chemically induced mammary carcinogenesis in rats. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20100901
Suppressive effect of global DNA hypomethylation on gastric carcinogenesis. Carcinogenesis 20100901
Micronutrient synergy--a new tool in effective control of metastasis and other key mechanisms of cancer. Cancer metastasis reviews 20100901
Canola oil inhibits breast cancer cell growth in cultures and in vivo and acts synergistically with chemotherapeutic drugs. Lipids 20100901
Intestinal metaplasia -the effect of Acid on the gastric mucosa and gastric carcinogenesis-. Journal of toxicologic pathology 20100901
Ezetimibe reverses the inhibitory effects of dietary cholesterol on mammary tumorigenesis in rats. International journal of cancer 20100815
Evolution on experimental animal model for upper urothelium carcinogenesis. World journal of urology 20100801
[Improvement of mouse model for thymic lymphoma induced by N-methyl-N-nitrosourea]. Zhongguo shi yan xue ye xue za zhi 20100801
Wheel running, skeletal muscle aerobic capacity and 1-methyl-1-nitrosourea induced mammary carcinogenesis in the rat. Carcinogenesis 20100701
Inhibitor of kappaB kinase beta regulates gastric carcinogenesis via interleukin-1alpha expression. Gastroenterology 20100701
Radical mechanisms in nitrosamine- and nitrosamide-induced whole-genome gene expression modulations in Caco-2 cells. Toxicological sciences : an official journal of the Society of Toxicology 20100701
Reduction of major histocompatibility complex class I expression on bladder carcinoma following tumor antigen-pulsed dendritic cell vaccine: Implications for immunoresistance in therapy. International journal of urology : official journal of the Japanese Urological Association 20100701
Animal models for retinitis pigmentosa induced by MNU; disease progression, mechanisms and therapeutic trials. Histology and histopathology 20100701
Dynamic spectral-domain optical coherence elastography for tissue characterization. Optics express 20100621
Mutagenicity of N-ethyl-N-nitrosourea, N-methyl-N-nitrosourea, methyl methanesulfonate and ethyl methanesulfonate in the developing Syrian hamster fetus. Mutation research 20100617
Integration of mutation and chromosomal damage endpoints into 28-day repeat dose toxicology studies. Toxicological sciences : an official journal of the Society of Toxicology 20100601
Genetic and environmental melanoma models in fish. Pigment cell & melanoma research 20100601
Methylnitrosourea induces neural progenitor cell apoptosis and microcephaly in mouse embryos. Birth defects research. Part B, Developmental and reproductive toxicology 20100601
Superior anticarcinogenic activity of trans,trans-conjugated linoleic acid in N-methyl-N-nitrosourea-induced rat mammary tumorigenesis. Journal of agricultural and food chemistry 20100512
Arsenic-specific stem cell selection during malignant transformation. Journal of the National Cancer Institute 20100505
Methylselenocysteine resets the rhythmic expression of circadian and growth-regulatory genes disrupted by nitrosomethylurea in vivo. Cancer prevention research (Philadelphia, Pa.) 20100501
Progression from chronic atrophic gastritis to gastric cancer; tangle, toggle, tackle with Korea red ginseng. Journal of clinical biochemistry and nutrition 20100501
[Hematological toxicity of some combined chemotherapy schemes involving aranoza]. Eksperimental'naia i klinicheskaia farmakologiia 20100501
A surprising link between the energetics of ovariectomy-induced weight gain and mammary tumor progression in obese rats. Obesity (Silver Spring, Md.) 20100401
Modulation of carbohydrate metabolism during N-methyl N-nitrosourea induced neurotoxicity in mice: role of curcumin. Neurochemical research 20100401
Genomics and bioinformatics resources for crop improvement. Plant & cell physiology 20100401
Protective effect of catechin on apoptosis of the lens epithelium in rats with N-methyl-N-nitrosourea-induced cataracts. Korean journal of ophthalmology : KJO 20100401
Pig-a mutation: kinetics in rat erythrocytes following exposure to five prototypical mutagens. Toxicological sciences : an official journal of the Society of Toxicology 20100301
Ganoderma spore lipid inhibits N-methyl-N-nitrosourea-induced retinal photoreceptor apoptosis in vivo. Experimental eye research 20100301
Null activity of selenium and vitamin e as cancer chemopreventive agents in the rat prostate. Cancer prevention research (Philadelphia, Pa.) 20100301
The impact of fish oil on the chemopreventive efficacy of tamoxifen against development of N-methyl-N-nitrosourea-induced rat mammary carcinogenesis. Cancer prevention research (Philadelphia, Pa.) 20100301
Different experimental approaches in modelling cataractogenesis: An overview of selenite-induced nuclear cataract in rats. Interdisciplinary toxicology 20100301
Spontaneous Malignant T-cell Lymphoma in a Young Adult Crl:CD (SD) Rat. Journal of toxicologic pathology 20100301
Prostate carcinogenesis induced by N-methyl-N-nitrosourea (mnu) in gerbils: histopathological diagnosis and potential invasiveness mediated by extracellular matrix components. Experimental and molecular pathology 20100201
Flavonoid profiling and transcriptome analysis reveals new gene-metabolite correlations in tubers of Solanum tuberosum L. Journal of experimental botany 20100201
Lack of modifying effects of prepubertal exposure to acrylamide (AA) on N-methyl-N-nitrosourea (MNU)-induced multi-organ carcinogenesis in F344 rats. The Journal of toxicological sciences 20100201
SPL28 encodes a clathrin-associated adaptor protein complex 1, medium subunit micro 1 (AP1M1) and is responsible for spotted leaf and early senescence in rice (Oryza sativa). The New phytologist 20100101
Rat medium-term multi-organ carcinogenesis bioassay of Agaricus blazei Murrill fruit-body extract. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101
Alternative mouse models for carcinogenicity assessment: industry use and issues with pathology interpretation. Toxicologic pathology 20100101
Intrinsic susceptibility MR imaging of chemically induced rat mammary tumors: relationship to histologic assessment of hypoxia and fibrosis. Radiology 20100101
Celecoxib inhibits CD133-positive cell migration via reduction of CCR2 in Helicobacter pylori-infected Mongolian gerbils. Digestion 20100101
A high protein moderate carbohydrate diet fed at discrete meals reduces early progression of N-methyl-N-nitrosourea-induced breast tumorigenesis in rats. Nutrition & metabolism 20100101
Upstream molecular signaling pathways of p27(Kip1) expression: effects of 4-hydroxytamoxifen, dexamethasone, and retinoic acids. Cancer cell international 20100101
Maternal characteristics associated with the dietary intake of nitrates, nitrites, and nitrosamines in women of child-bearing age: a cross-sectional study. Environmental health : a global access science source 20100101
N-nitroso-N-methylurea and N-nitroso-N-ethylurea induce upregulation of cellular NF-kappa B activity through protein kinase C-dependent pathway in human malignant keratinocytes. Archives of pharmacal research 20100101
Early limited nitrosamine exposures exacerbate high fat diet-mediated type 2 diabetes and neurodegeneration. BMC endocrine disorders 20100101
The bright and the dark sides of DNA repair in stem cells. Journal of biomedicine & biotechnology 20100101
Malignant precursor cells pre-exist in human breast DCIS and require autophagy for survival. PloS one 20100101
View and review on viral oncology research. Infectious agents and cancer 20100101
Cell cycle and anti-estrogen effects synergize to regulate cell proliferation and ER target gene expression. PloS one 20100101
Enhanced mammary progesterone receptor-A isoform activity in the promotion of mammary tumor progression by dietary soy in rats. Nutrition and cancer 20100101
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Genetic integrity of the human Y chromosome exposed to groundwater arsenic. BMC medical genomics 20100101
Cancer biomarker discovery: the entropic hallmark. PloS one 20100101
Fluorescence in situ hybridization in combination with the comet assay and micronucleus test in genetic toxicology. Molecular cytogenetics 20100101
Aggressive mammary carcinoma progression in Nrf2 knockout mice treated with 7,12-dimethylbenz[a]anthracene. BMC cancer 20100101
p27(Kip1) deficiency promotes prostate carcinogenesis but does not affect the efficacy of retinoids in suppressing the neoplastic process. BMC cancer 20100101
Anti-apoptotic effect of claudin-1 in tamoxifen-treated human breast cancer MCF-7 cells. BMC cancer 20100101
Genomic analysis of microRNA time-course expression in liver of mice treated with genotoxic carcinogen N-ethyl-N-nitrosourea. BMC genomics 20100101
Repair of DNA Alkylation Damage by the Escherichia coli Adaptive Response Protein AlkB as Studied by ESI-TOF Mass Spectrometry. Journal of nucleic acids 20100101
Is the comet assay a sensitive procedure for detecting genotoxicity? Journal of nucleic acids 20100101
DNA damage induced by alkylating agents and repair pathways. Journal of nucleic acids 20100101
Formation and repair of tobacco carcinogen-derived bulky DNA adducts. Journal of nucleic acids 20100101
Collection of epithelial cells from rodent mammary gland via laser capture microdissection yielding high-quality RNA suitable for microarray analysis. Biological procedures online 20100101
A method for serial tissue processing and parallel analysis of aberrant crypt morphology, mucin depletion, and Beta-catenin staining in an experimental model of colon carcinogenesis. Biological procedures online 20100101
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Vitamin D3 affects expression of thyroid hormone receptor alpha and deiodinase activity in liver of MNU-treated Sprague-Dawley rats. General physiology and biophysics 20091201
Lesions in the Larynx of Wistar RccHan: WIST Rats. Journal of toxicologic pathology 20091201
Map-based cloning of the ERECT PANICLE 3 gene in rice. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20091101
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Increased H-ras mutation frequency in mammary tumors of rats initiated with N-methyl-N-nitrosourea (MNU) and treated with acrylamide. The Journal of toxicological sciences 20091001
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[Establishment of an animal model with thymic lymphoma in mice]. Zhongguo shi yan xue ye xue za zhi 20091001
Rat brain tumor models in experimental neuro-oncology: the C6, 9L, T9, RG2, F98, BT4C, RT-2 and CNS-1 gliomas. Journal of neuro-oncology 20090901
Negation of the cancer-preventive actions of selenium by over-expression of protein kinase Cepsilon and selenoprotein thioredoxin reductase. Carcinogenesis 20090901
Cell death induced by N-methyl-N-nitrosourea, a model S(N)1 methylating agent, in two lung cancer cell lines of human origin. Apoptosis : an international journal on programmed cell death 20090901
Malignant Lymphoma with Severe Infiltrative Growth into Skeletal Muscles in WBN/Kob Rats. Journal of toxicologic pathology 20090901
MLH1 mediates PARP-dependent cell death in response to the methylating agent N-methyl-N-nitrosourea. British journal of cancer 20090804
Non-linear dose-response of DNA-reactive genotoxins: recommendations for data analysis. Mutation research 20090801
Dose-response and operational thresholds/NOAELs for in vitro mutagenic effects from DNA-reactive mutagens, MMS and MNU. Mutation research 20090801
Pitavastatin fails to lower serum lipid levels or inhibit gastric carcinogenesis in helicobacter pylori-infected rodent models. Cancer prevention research (Philadelphia, Pa.) 20090801
Detection of localized retinal malfunction in retinal degeneration model using a multielectrode array system. Journal of neuroscience research 20090701
Gastric carcinogenesis by N-Methyl-N-nitrosourea is enhanced in db/db diabetic mice. Cancer science 20090701
Mixed tocopherols prevent mammary tumorigenesis by inhibiting estrogen action and activating PPAR-gamma. Clinical cancer research : an official journal of the American Association for Cancer Research 20090615
Expression order of alpha-v and beta-3 integrin subunits in the N-methyl-N-nitrosourea-induced rat mammary tumor model. Cancer investigation 20090601
Genetic analysis of pigmented tuber flesh in potato. TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik 20090601
Chemopreventive effect of 4-[3,5-Bis(trimethylsilyl) benzamido] benzoic acid (TAC-101) on MNU-induced colon carcinogenesis in a rat model. Anticancer research 20090601
Antimutagenic effect of phenethyl isothiocyanate. Central European journal of public health 20090601
Early remodeling in an inducible animal model of retinal degeneration. Neuroscience 20090505
High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not always accompanied by reduction in p27Kip1. International journal of oncology 20090501
The association between phenotype and size of breast tumors induced by 1-methyl-1-nitrosourea (MNU) injection in rats. Medical science monitor : international medical journal of experimental and clinical research 20090501
Induction of excision repairable DNA lesions in lymphocytes exposed to lead and ALA in vitro. Biological trace element research 20090401
Decreasing hormonal promotion is key to breast cancer prevention. Endocrine 20090401
Molecular signatures of N-nitroso compounds in Caco-2 cells: implications for colon carcinogenesis. Toxicological sciences : an official journal of the Society of Toxicology 20090401
Disruption of a mitochondrial MutS DNA repair enzyme homologue confers drug resistance in the parasite Toxoplasma gondii. Molecular microbiology 20090401
Effects of physical activity and restricted energy intake on chemically induced mammary carcinogenesis. Cancer prevention research (Philadelphia, Pa.) 20090401
Etiology of MNU-induced melanomas in Xiphophorus hybrids. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090301
N-methylnitrosourea induced breast cancer in rat, the histopathology of the resulting tumours and its drawbacks as a model. Pathology oncology research : POR 20090301
Energetics and mammary carcinogenesis: effects of moderate-intensity running and energy intake on cellular processes and molecular mechanisms in rats. Journal of applied physiology (Bethesda, Md. : 1985) 20090301
E-cadherin deficiency initiates gastric signet-ring cell carcinoma in mice and man. Cancer research 20090301
Interleukin-24 induces expression of beta4 integrin but suppresses anchorage-independent growth of rat mammary tumor cells by a mechanism that is independent of beta4. Molecular cancer research : MCR 20090301
Biological Basis of Differential Susceptibility to Hepatocarcinogenesis among Mouse Strains. Journal of toxicologic pathology 20090301
A novel protein, MAPO1, that functions in apoptosis triggered by O6-methylguanine mispair in DNA. Oncogene 20090226
Inflammatory processes of prostate tissue microenvironment drive rat prostate carcinogenesis: preventive effects of celecoxib. The Prostate 20090201
Lack of efficacy of the statins atorvastatin and lovastatin in rodent mammary carcinogenesis. Cancer prevention research (Philadelphia, Pa.) 20090201
Coexistence of different tissue tumourigenesis in an N-methyl-N-nitrosourea-induced mammary carcinoma model: a histopathological report in Sprague-Dawley rats. Laboratory animals 20090101
Primary tumor cells obtained from MNU-induced mammary carcinomas show immune heterogeneity which can be modulated by low-efficiency transfection of CD40L gene. Cancer biology & therapy 20090101
Generation of immature retinal neurons from proliferating cells in the pars plana after retinal histogenesis in mice with retinal degeneration. Molecular vision 20090101
Side effects of anastrozole in the experimental pre-menopausal mammary carcinogenesis. Neoplasma 20090101
Celecoxib and melatonin in prevention of female rat mammary carcinogenesis. Neoplasma 20090101
Metformin in chemically-induced mammary carcinogenesis in rats. Neoplasma 20090101
[Restraining effects of acupuncture on photoreceptor cell apoptosis in rats with retinitis pigmentosa induced by N-methyl-N-nitrosourea]. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20090101
[Prognostic significance of lysosomal cysteine proteases in the estimation of the effectiveness of the antitumorigenic therapy]. Biomeditsinskaia khimiia 20090101
Acute doxorubicin pulmotoxicity in rats with malignant neoplasm is effectively treated with fullerenol C60(OH)24 through inhibition of oxidative stress. Pharmacological reports : PR 20090101
Genistein mechanisms and timing of prostate cancer chemoprevention in lobund-wistar rats. Asian Pacific journal of cancer prevention : APJCP 20090101
In vivo effect of an luteinizing hormone-releasing hormone analog on vascular endothelial growth factor and epidermal growth factor receptor expression in mammary tumors. Journal of carcinogenesis 20090101
Antineoplastic effect of iodine in mammary cancer: participation of 6-iodolactone (6-IL) and peroxisome proliferator-activated receptors (PPAR). Molecular cancer 20090101
[Effects of cascatol and sodium selenite on the onset and development of breast tumors induced in rats by N-methyl-N-nitrosourea]. Patologicheskaia fiziologiia i eksperimental'naia terapiia 20090101
Early modification of c-myc, Ha-ras and p53 expressions by chemical carcinogens (DMBA, MNU). In vivo (Athens, Greece) 20090101
New sources of soybean seed meal and oil composition traits identified through TILLING. BMC plant biology 20090101
Citrus auraptene suppresses cyclin D1 and significantly delays N-methyl nitrosourea induced mammary carcinogenesis in female Sprague-Dawley rats. BMC cancer 20090101
Histological analysis of low dose NMU effects in the rat mammary gland. BMC cancer 20090101
[Pre-clinical study of combined aranosa, cisplatin and irinotecan in the treatment of experimental lung cancer]. Voprosy onkologii 20090101
In vitro measures used to predict anticancer activity of apple cultivars and their comparison to outcomes from a rat model of experimentally induced breast cancer. Nutrition and cancer 20090101
A high-density collection of EMS-induced mutations for TILLING in Landsberg erecta genetic background of Arabidopsis. BMC plant biology 20090101
A novel Bifidobacterium infantis-mediated TK/GCV suicide gene therapy system exhibits antitumor activity in a rat model of bladder cancer. Journal of experimental & clinical cancer research : CR 20090101
Nitrosamine exposure exacerbates high fat diet-mediated type 2 diabetes mellitus, non-alcoholic steatohepatitis, and neurodegeneration with cognitive impairment. Molecular neurodegeneration 20090101
N-methyl-N-nitrosourea-induced retinal degeneration in mice is independent of the p53 gene. Molecular vision 20090101
Biphasic effect of short-term pregnancy hormone treatment on N-methyl-N-nitrosourea-induced mammary carcinogenesis in young and old rats. Molecular medicine reports 20090101
N-Methyl-N-Nitrosourea (MNU): A positive control chemical for p53+/- mouse carcinogenicity studies. Toxicologic pathology 20081201
Roles of cyclooxygenase-2 and microsomal prostaglandin E synthase-1 expression and beta-catenin activation in gastric carcinogenesis in N-methyl-N-nitrosourea-treated K19-C2mE transgenic mice. Cancer science 20081201
Detection of micronucleated cells and gene expression changes in glandular stomach of mice treated with stomach-targeted carcinogens. Mutation research 20081117
Carcinogen-induced gene promoter hypermethylation is mediated by DNMT1 and causal for transformation of immortalized bronchial epithelial cells. Cancer research 20081101
Gemini vitamin D analogues inhibit estrogen receptor-positive and estrogen receptor-negative mammary tumorigenesis without hypercalcemic toxicity. Cancer prevention research (Philadelphia, Pa.) 20081101
Dielectrophoretic field-flow fractionation system for detection of aquatic toxicants. Analytical chemistry 20081015
The effect of dietary supplementation with limonene or myo-inositol on the induction of neoplasia and matrix metalloproteinase and plasminogen activator activities in accessory sex organs of male Lobund-Wistar rats. Experimental and molecular pathology 20081001
Retina protective effect of acidic fibroblast growth factor after canceling its mitogenic activity. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20081001
Carcinogenic comparative study on rasH2 mice produced by two breeding facilities. The Journal of toxicological sciences 20081001
Diphenyl diselenide supplementation delays the development of N-nitroso-N-methylurea-induced mammary tumors. Archives of toxicology 20080901
Development of aberrant crypt foci in the colons of ob/ob and db/db mice: evidence that leptin is not a promoter. Molecular carcinogenesis 20080901
Characteristics of bone marrow-derived microglia in the normal and injured retina. Investigative ophthalmology & visual science 20080901
Placental oxidative stress alters expression of murine osteogenic genes and impairs fetal skeletal formation. Placenta 20080901
Analysis of caspase activities in rat mammary tumours induced by N-methyl-nitrosourea. Oncology reports 20080901
Protective effects of diets supplemented with omega-3 polyunsaturated fatty acids and calcium against colorectal tumor formation. Digestive diseases and sciences 20080801
The combination of genistin and ipriflavone prevents mammary tumorigenesis and modulates lipid profile. Clinical nutrition (Edinburgh, Scotland) 20080801
Transgenic cyclooxygenase-2 expression and high salt enhanced susceptibility to chemical-induced gastric cancer development in mice. Carcinogenesis 20080801
Effect of nonmotorized wheel running on mammary carcinogenesis: circulating biomarkers, cellular processes, and molecular mechanisms in rats. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080801
Alkylation damage causes MMR-dependent chromosomal instability in vertebrate embryos. Nucleic acids research 20080701
c-Jun NH2-terminal kinase 1 is a critical regulator for the development of gastric cancer in mice. Cancer research 20080701
Mutation of the plastidial alpha-glucan phosphorylase gene in rice affects the synthesis and structure of starch in the endosperm. The Plant cell 20080701
Chemopreventive doses of methylselenocysteine alter circadian rhythm in rat mammary tissue. Cancer prevention research (Philadelphia, Pa.) 20080701
Intravitreal injection of fluorochrome-conjugated peanut agglutinin results in specific and reversible labeling of mammalian cones in vivo. Investigative ophthalmology & visual science 20080601
Interaction of tomato lycopene and ketosamine against rat prostate tumorigenesis. Cancer research 20080601
Proliferation of the superficial epithelium of ovaries in senile female rats following oral administration of conjugated equine estrogens. Clinics (Sao Paulo, Brazil) 20080601
Chemical carcinogenesis studies in nonhuman primates. Proceedings of the Japan Academy. Series B, Physical and biological sciences 20080601
Application of TILLING and EcoTILLING as Reverse Genetic Approaches to Elucidate the Function of Genes in Plants and Animals. Current genomics 20080601
Possible carcinogenic risks of copper gluconate and their prevention by co-administered green tea catechins evaluated by a rat medium-term multi-organ carcinogenicity bioassay protocol. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080501
Recommendations for design of the rat comet assay. Mutagenesis 20080501
Two hour exposure to sodium butyrate sensitizes bladder cancer to anticancer drugs. International journal of urology : official journal of the Japanese Urological Association 20080501
[Methylnitrosourea as challenge mutagen in assessment of the DNA mismatch repair (MMR) activity: association with some types of cancer]. Genetika 20080501
Mutagenic effects of poly (ADP-ribose) polymerase-1 deficiency in transgenic mice. Mutation research 20080402
Reduced methylation-induced mutagenesis in rat splenocytes in vivo by sub-chronic low dose exposure to N-metyl-N-nitrosourea. Mutation research 20080402
Melatonin, environmental light, and breast cancer. Breast cancer research and treatment 20080401
4-Vinyl-2,6-dimethoxyphenol (canolol) suppresses oxidative stress and gastric carcinogenesis in Helicobacter pylori-infected carcinogen-treated Mongolian gerbils. International journal of cancer 20080401
Dietary soy protein inhibits DNA damage and cell survival of colon epithelial cells through attenuated expression of fatty acid synthase. American journal of physiology. Gastrointestinal and liver physiology 20080401
Effects of gefitinib (Iressa) on mammary cancers: preventive studies with varied dosages, combinations with vorozole or targretin, and biomarker changes. Molecular cancer therapeutics 20080401
Promotion potential of madder color in a medium-term multi-organ carcinogenesis bioassay model in F344 rats. Journal of food science 20080401
Mutationally activated K-ras 4A and 4B both mediate lung carcinogenesis. Experimental cell research 20080310
MNU-induced mutant pools and high performance TILLING enable finding of any gene mutation in rice. Molecular genetics and genomics : MGG 20080301
The mechanisms of alloxan- and streptozotocin-induced diabetes. Diabetologia 20080201
Protective effect of Acticoa powder, a cocoa polyphenolic extract, on prostate carcinogenesis in Wistar-Unilever rats. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20080201
Induction of a novel histone deacetylase 1/c-Myc/Mnt/Max complex formation is implicated in parity-induced refractoriness to mammary carcinogenesis. Cancer science 20080201
Comparative genomics of susceptibility to mammary carcinogenesis among inbred rat strains: role of reduced prolactin signaling in resistance of the Copenhagen strain. Carcinogenesis 20080101
Preferential regeneration of photoreceptor from Müller glia after retinal degeneration in adult rat. Vision research 20080101
Identification of photoreceptor precursors in the pars plana during ocular development and after retinal injury. Investigative ophthalmology & visual science 20080101
Preventive effects of letrozole in the model of premenopausal mammary carcinogenesis. Neoplasma 20080101
TILLING to detect induced mutations in soybean. BMC plant biology 20080101
[New approaches to the drug prophylaxis of mammary tumor: evaluation of the prophylactic effect of lovastatin and captopril in rats with experimental mammary gland tumors]. Eksperimental'naia i klinicheskaia farmakologiia 20080101
Mitochondrial superoxide dismutase activation with 17 beta-estradiol-treated human lens epithelial cells. Molecular vision 20080101
Hormonal prevention of breast cancer: significance of promotional environment. Advances in experimental medicine and biology 20080101
Hormones of pregnancy, alpha-feto protein, and reduction of breast cancer risk. Advances in experimental medicine and biology 20080101
The Roles of Dietary PPARgamma Ligands for Metastasis in Colorectal Cancer. PPAR research 20080101
PPARgamma and MEK Interactions in Cancer. PPAR research 20080101
[Verbena canadensis Britt mutants with altered development of flowers and inflorescences generated by chemical mutagenesis]. Ontogenez 20080101
Inhibition of prostate cancer metastasis by administration of a tissue vaccine. Clinical & experimental metastasis 20080101
Celecoxib inhibits apurinic/apyrimidinic endonuclease-1 expression and prevents gastric cancer in Helicobacter pylori-infected mongolian gerbils. Digestion 20080101
Neoplastic effects of exemestane in premenopausal breast cancer model. Neoplasma 20080101
Effects of different dietary fatty acids on the fatty acid compositions and the expression of lipid metabolic-related genes in mammary tumor tissues of rats. Nutrition and cancer 20080101
Chemopreventive effects of anastrozole in a premenopausal breast cancer model. Anticancer research 20080101
Acute doxorubicin nephrotoxicity in rats with malignant neoplasm can be successfully treated with fullerenol C60(OH)24 via suppression of oxidative stress. Pharmacological reports : PR 20080101
[Clinical features and combined treatment of the central nervous system in Hodgkin's disease]. Voprosy onkologii 20080101
Glaucoma alters the circadian timing system. PloS one 20080101
Early modification of c-myc, Ha-ras and p53 expressions by N-methyl-N-nitrosourea. In vivo (Athens, Greece) 20080101
Gene expression analysis of biological systems driving an organotypic model of endometrial carcinogenesis and chemoprevention. Gene regulation and systems biology 20080101
Effects of dietary energy restriction on gene regulation in mammary epithelial cells. Cancer research 20071215
Ataxia telangiectasia-mutated and p53 are potential mediators of chloroquine-induced resistance to mammary carcinogenesis. Cancer research 20071215
A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models. Breast cancer research and treatment 20071201
Gpx2 is an overexpressed gene in rat breast cancers induced by three different chemical carcinogens. Cancer research 20071201
Molecular analysis of rat mammary carcinogenesis: an approach from carcinogenesis research to cancer prevention. Medical molecular morphology 20071201
Altering DNA base excision repair: use of nuclear and mitochondrial-targeted N-methylpurine DNA glycosylase to sensitize astroglia to chemotherapeutic agents. Glia 20071101
Inhibitory effect of nordihydroguaiaretic acid, a plant lignan, on Helicobacter pylori-associated gastric carcinogenesis in Mongolian gerbils. Cancer science 20071101
Advanced rat mammary cancers are growth hormone dependent. Endocrinology 20071001
Exisulind in combination with celecoxib modulates epidermal growth factor receptor, cyclooxygenase-2, and cyclin D1 against prostate carcinogenesis: in vivo evidence. Clinical cancer research : an official journal of the American Association for Cancer Research 20071001
Cancer resistance in amphibians. Alternatives to laboratory animals : ATLA 20071001
Richard Clothier: an appreciation. Alternatives to laboratory animals : ATLA 20071001
Short-term modulation of cell proliferation and apoptosis and preventive/therapeutic efficacy of various agents in a mammary cancer model. Clinical cancer research : an official journal of the American Association for Cancer Research 20070915
[Retinal gene expression profiles of MNU-induced rat retinal degeneration treated with qijudihuangtang]. Yan ke xue bao = Eye science 20070901
Serial transplantation of NMU-induced rat mammary tumors: a model of human breast cancer progression. International journal of cancer 20070801
Methylation damage response in hematopoietic progenitor cells. DNA repair 20070801
Characterization of SSIIIa-deficient mutants of rice: the function of SSIIIa and pleiotropic effects by SSIIIa deficiency in the rice endosperm. Plant physiology 20070801
N-methyl-N-nitrosourea-induced mammary carcinogenesis is promoted by short-term treatment with estrogen and progesterone mimicking pregnancy in aged female Lewis rats. Oncology reports 20070801
Animal models of stomach carcinogenesis. Toxicologic pathology 20070801
A method of producing carcinoma in upper aerodigestive tree and esophagus of the Syrian golden hamster using wounding and instillation of N-methylnitrosourea. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070801
Inhibition of nuclear factor-kappaB activity by temozolomide involves O6-methylguanine induced inhibition of p65 DNA binding. Cancer research 20070715
Preventive effects of polyphenon E on urinary bladder and mammary cancers in rats and correlations with serum and urine levels of tea polyphenols. Molecular cancer therapeutics 20070701
[Effects of different dietary fatty acid on expression of nuclear receptor genes in breast cancer of rats]. Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] 20070701
Expression profiling of rat mammary epithelial cells reveals candidate signaling pathways in dietary protection from mammary tumors. Physiological genomics 20070619
Mammary carcinogenesis in transgenic mice expressing a dominant-negative mutant of DNA polymerase beta in their mammary glands. Carcinogenesis 20070601
Role of bacterial strain diversity of Helicobacter pylori in gastric carcinogenesis induced by N-methyl-N-nitrosourea in Mongolian gerbils. Helicobacter 20070601
Genetic ablation of cone photoreceptors eliminates retinal folds in the retinal degeneration 7 (rd7) mouse. Investigative ophthalmology & visual science 20070601
The National Cancer Institute of Canada Clinical Trials Group MAP.3 trial: an international breast cancer prevention trial. Current oncology (Toronto, Ont.) 20070601
The chemopreventive effect of retinoids on cellular NF-kappaB activity induced by NMU and NEU in human malignant keratinocytes. Cancer research and treatment : official journal of Korean Cancer Association 20070601
Microarray expression analysis of the early N-methy-N-nitrosourea-induced retinal degeneration in rat. Neuroscience letters 20070511
Nitric oxide donors attenuate clongenic potential in rat C6 glioma cells treated with alkylating chemotherapeutic agents. Neuroscience letters 20070511
In utero exposure to maternal diets containing soy protein isolate, but not genistein alone, protects young adult rat offspring from NMU-induced mammary tumorigenesis. Carcinogenesis 20070501
Protective role of connexin 32 in steady-state hematopoiesis, regeneration state, and leukemogenesis. Experimental biology and medicine (Maywood, N.J.) 20070501
Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway. Cancer research 20070501
Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens. Cancer research 20070415
Antitumour action of 5,6-dimethylxanthenone-4-acetic acid in rats bearing chemically induced primary mammary tumours. Cancer chemotherapy and pharmacology 20070401
[Mismatch repair (MMR) efficiency and MSH2 gene mutation in human colorectal carcinoma cell line COLO320HSR]. Genetika 20070401
Contribution of calpains to photoreceptor cell death in N-methyl-N-nitrosourea-treated rats. Experimental neurology 20070301
Loss of chromosomal integrity drives rat mammary tumorigenesis. International journal of cancer 20070301
Comparison of the genetic effects of equimolar doses of ENU and MNU: while the chemicals differ dramatically in their mutagenicity in stem-cell spermatogonia, both elicit very high mutation rates in differentiating spermatogonia. Mutation research 20070301
Differential expression of prohibitin is correlated with dual action of Vitamin D as a proliferative and antiproliferative hormone in breast epithelial cells. The Journal of steroid biochemistry and molecular biology 20070301
Ferulic Acid: therapeutic potential through its antioxidant property. Journal of clinical biochemistry and nutrition 20070301
Potassium diazoacetate-induced p53 mutations in vitro in relation to formation of O6-carboxymethyl- and O6-methyl-2'-deoxyguanosine DNA adducts: relevance for gastrointestinal cancer. Carcinogenesis 20070201
Urinary phytoestrogen excretion of rats bearing methylnitrosourea-induced mammary carcinoma in response to treatment with 2-methoxyestradiol. The Journal of steroid biochemistry and molecular biology 20070201
Quantitative structure-activity relationships for toxicity and genotoxicity of halogenated aliphatic compounds: wing spot test of Drosophila melanogaster. Chemosphere 20070201
Poly (ADP-ribose) polymerase inhibitor 3-aminobenzamide rescues N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats through preservation of nuclear factor-kappaB activity. Experimental eye research 20070201
Expression of voltage-gated potassium channels in human and mouse colonic carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research 20070201
Does immune stimulation or antioxidant therapy reduce MNU-induced placental damage via activation of Jak-STAT and NFkappaB signaling pathways? Placenta 20070101
Characterization of a preclinical model of simultaneous breast and ovarian cancer progression. Carcinogenesis 20070101
Atorvastatin has cardiac safety at intensive cholesterol-reducing protocols for long term, yet its cancer-treatment doses with chemotherapy may cause cardiomyopathy even under coenzyme-Q10 protection. Cell biochemistry and function 20070101
Chemoprevention of aberrant crypt foci in the colon of rats by dietary onion. European journal of cancer (Oxford, England : 1990) 20070101
[Gastric cancer and eradication of H. pylori]. Gan to kagaku ryoho. Cancer & chemotherapy 20070101
Effects of eradication of Helicobacter pylori on gastric carcinogenesis in experimental models. Journal of gastroenterology 20070101
Effects of liarozole fumarate (R85246) in combination with tamoxifen on N-methyl-N-nitrosourea (MNU)-induced mammary carcinoma and uterus in the rat model. BMC cancer 20070101
Quantitation of lower levels of the DNA adduct of thymidylyl(3'-5')thymidine methyl phosphotriester by liquid chromatography/negative atmospheric pressure chemical ionization tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20070101
Association of estrogen receptor-alpha and progesterone receptor A expression with hormonal mammary carcinogenesis: role of the host microenvironment. Breast cancer research : BCR 20070101
Prenatal bisphenol A exposure induces preneoplastic lesions in the mammary gland in Wistar rats. Environmental health perspectives 20070101
Roles for estrogen and progesterone in breast cancer prevention. Breast cancer research : BCR 20070101
Discovery of chemically induced mutations in rice by TILLING. BMC plant biology 20070101
Effect of prolonged psychoemotional stress and melatonin on experimental mammary carcinogenesis in female rats. Neoplasma 20070101
Interaction between ATM and PARP-1 in response to DNA damage and sensitization of ATM deficient cells through PARP inhibition. BMC molecular biology 20070101
Multicolour FISH in an analysis of chromosome aberrations induced by N-nitroso-N-methylurea and maleic hydrazide in barley cells. Journal of applied genetics 20070101
Chemoprevention of rat prostate carcinogenesis by soy isoflavones and by Bowman-Birk inhibitor. Nutrition and cancer 20070101
Null effect of dietary restriction on prostate carcinogenesis in the Wistar-Unilever rat. Nutrition and cancer 20070101
Intestinal phenotypes of stomach cancers arising after Helicobacter pylori eradication in carcinogen-treated Mongolian gerbils. Asian Pacific journal of cancer prevention : APJCP 20070101
Chondroitinase ABC treatment enhances synaptogenesis between transplant and host neurons in model of retinal degeneration. Cell transplantation 20070101
Mixed tocopherols inhibit N-methyl-N-nitrosourea-induced mammary tumor growth in rats. Nutrition and cancer 20070101
PARP inhibitors accelerate N-methyl-N-nitrosourea-induced cataractogenesis in Sprague-Dawley rats. In vivo (Athens, Greece) 20070101
Prolactin, TNF alpha and nitric oxide expression in nitroso-N-methylurea-induced-mammary tumours. Journal of carcinogenesis 20070101
Effects of prepubertal indole-3-carbinol treatment on development of N-methyl-N-nitrosourea-induced mammary carcinomas in female Sprague-Dawley rats. In vivo (Athens, Greece) 20070101
[Combination chemotherapy with newly-developed cytostatics for disseminated small cell lung cancer]. Voprosy onkologii 20070101
Overexpression of the DNA mismatch repair factor, PMS2, confers hypermutability and DNA damage tolerance. Cancer letters 20061208
Effect of the co-administration of phenobarbital, quercetin and mancozeb on nitrosomethylurea-induced pancreatic tumors in rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20061201
Inhibitory effects of Hochu-ekki-to on endometrial carcinogenesis induced by N-methyl-N-nitrosourea and 17beta-estradiol in mice. Oncology reports 20061201
Use of IC tags in short-term carcinogenicity study on CB6F1 TGrasH2 mice. The Journal of toxicological sciences 20061201
Dietary prevention of hormone refractory prostate cancer in Lobund-Wistar rats: a review of studies in a relevant animal model. Comparative medicine 20061201
Sensitivity of human lymphocytes to genotoxic effect of n-methyl-n-nitrosourea: possible relation to gynecological cancers. Experimental oncology 20061201
Quantification of O6-methyl and O6-ethyl deoxyguanosine adducts in C57BL/6N/Tk+/- mice using LC/MS/MS. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061121
Genistein enhances N-nitrosomethylurea-induced rat mammary tumorigenesis. Cancer letters 20061008
High salt diets dose-dependently promote gastric chemical carcinogenesis in Helicobacter pylori-infected Mongolian gerbils associated with a shift in mucin production from glandular to surface mucous cells. International journal of cancer 20061001
Effects of ginger (Zingiber officinale Roscoe) on DNA damage and development of urothelial tumors in a mouse bladder carcinogenesis model. Environmental and molecular mutagenesis 20061001
Sensitization by dietary docosahexaenoic acid of rat mammary carcinoma to anthracycline: a role for tumor vascularization. Clinical cancer research : an official journal of the American Association for Cancer Research 20061001
Letter to the editor. Molecular and cellular endocrinology 20060926
Vanillin as a modulator agent in SMART test: inhibition in the steps that precede N-methyl-N-nitrosourea-, N-ethyl-N-nitrosourea-, ethylmethanesulphonate- and bleomycin-genotoxicity. Mutation research 20060905
Enhancement of mammary carcinogenesis in two rodent models by silymarin dietary supplements. Carcinogenesis 20060901
Intravesical N-(4-hydroxyphenyl) retinamide and adriamycin induces apoptosis in bladder cancer. Frontiers in bioscience : a journal and virtual library 20060901
Immunohistochemical analysis for cell regulatory proteins in bladder carcinogenesis induced by N-methyl-N-nitrosourea-terephthalic acid. Environmental toxicology and pharmacology 20060901
Carcinogens induce genome-wide loss of heterozygosity in normal stem cells without persistent chromosomal instability. Proceedings of the National Academy of Sciences of the United States of America 20060801
Efficacy of the farnesyltransferase inhibitor R115777 in a rat mammary tumor model: role of Ha-ras mutations and use of microarray analysis in identifying potential targets. Carcinogenesis 20060701
Differential susceptibility to chemically induced thymic lymphomas in SENCARB and SSIN inbred mice. Molecular carcinogenesis 20060701
A comparative study on the protective effects of 17beta-estradiol, biochanin A and bisphenol A on mammary gland differentiation and tumorigenesis in rats. Indian journal of experimental biology 20060701
Efficacy of new retinoids in the prevention of mammary cancers and correlations with short-term biomarkers. Carcinogenesis 20060601
The parity-related protection against breast cancer is compromised by cigarette smoke during rat pregnancy: observations on tumorigenesis and immunological defenses of the neonate. Carcinogenesis 20060601
Characterization and mapping of a shattering mutant in rice that corresponds to a block of domestication genes. Genetics 20060601
Acute photoreceptor degeneration down-regulates melanopsin expression in adult rat retina. Neuroscience letters 20060529
Refractive index of carcinogen-induced rat mammary tumours. Physics in medicine and biology 20060507
[Changes of NF-kappaB/I kappa B alpha in N-methyl-N-nitrosourea-induced retinal damage in rats]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20060501
Simultaneous quantitation of 7-methyl- and O6-methylguanine adducts in DNA by liquid chromatography-positive electrospray tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060403
Parous mammary glands exhibit distinct alterations in gene expression and proliferation responsiveness to carcinogenic stimuli in Lewis rats. Oncology reports 20060401
Dietary gamma-linolenate attenuates tumor growth in a rodent model of prostatic adenocarcinoma via suppression of elevated generation of PGE(2) and 5S-HETE. Prostaglandins, leukotrienes, and essential fatty acids 20060401
DNA copy number alterations and expression of relevant genes in mouse thymic lymphomas induced by gamma-irradiation and N-methyl-N-nitrosourea. Cancer genetics and cytogenetics 20060401
Effects of the farnesyl transferase inhibitor R115777 (Zarnestra) on mammary carcinogenesis: prevention, therapy, and role of HaRas mutations. Molecular cancer therapeutics 20060401
Deregulation of homologous recombination DNA repair in alkylating agent-treated stem cell clones: a possible role in the aetiology of chemotherapy-induced leukaemia. Oncogene 20060316
Nicotinamide blocks N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in rats through poly (ADP-ribose) polymerase activity and Jun N-terminal kinase/activator protein-1 pathway inhibition. Experimental eye research 20060301
Renin-angiotensin system-regulating aminopeptidase activities are modified in the pineal gland of rats with breast cancer induced by N-methyl-nitrosourea. Cancer investigation 20060301
Open access to breast tumours. The Lancet. Oncology 20060301
Phosphate alkylation in different DNA substrates: the role of local DNA sequence and electrophile character in determining the nonrandom nature of phosphotriester adduct formation. Chemical research in toxicology 20060301
A mutant mouse with a highly specific contextual fear-conditioning deficit found in an N-ethyl-N-nitrosourea (ENU) mutagenesis screen. Learning & memory (Cold Spring Harbor, N.Y.) 20060301
Quantification of CD59- mutants in human-hamster hybrid (AL) cells by flow cytometry. Mutation research 20060222
Streptozotocin inhibits O-GlcNAcase via the production of a transition state analog. Biochemical and biophysical research communications 20060210
Prebreeding maternal immunostimulation with Freund's complete adjuvant reduces placental damage and distal limb defects caused by methylnitrosourea. American journal of reproductive immunology (New York, N.Y. : 1989) 20060201
Chemoprevention of rat prostate carcinogenesis by diallyl disulfide, an organosulfur compound of garlic. Biological & pharmaceutical bulletin 20060201
Mechanisms of formation of micronuclei in somatic cells of tailless amphibians normally and under the effect of N-nitroso-N-methylcarbamide. Bulletin of experimental biology and medicine 20060201
Role of maternal dietary antioxidant supplementation in murine placental and fetal limb development. Placenta 20060101
Modification of N-Methyl-N-Nitrosourea initiated bladder carcinogenesis in Wistar rats by terephthalic acid. Toxicology and applied pharmacology 20060101
Hexachlorobenzene is a tumor co-carcinogen and induces alterations in insulin-growth factors signaling pathway in the rat mammary gland. Toxicological sciences : an official journal of the Society of Toxicology 20060101
Gastric and intestinal phenotypes and histogenesis of advanced glandular stomach cancers in carcinogen-treated, Helicobacter pylori-infected Mongolian gerbils. Cancer science 20060101
Effects of gender and gonad status on N-methyl-N-nitrosourea-induced cataractogenesis and retinopathy in Lewis rats. In vivo (Athens, Greece) 20060101
[Comparison of geno- and cytotoxicity of methylnitrosourea on MMR-proficient and MMR-deficient human tumor cell lines]. Tsitologiia 20060101
Insulin-regulated aminopeptidase/placental leucil Aminopeptidase (IRAP/P-lAP) and angiotensin IV-forming activities are modified in serum of rats with breast cancer induced by N-methyl-nitrosourea. Anticancer research 20060101
Simple tandem repeat (TTTA)n polymorphism in CYP19 (aromatase) gene and breast cancer risk in Nigerian women. Journal of carcinogenesis 20060101
DNA damage induced by mutagens in plant and human cell nuclei in acellular comet assay. Folia histochemica et cytobiologica 20060101
Effect of rosiglitazone on N-nitroso-N-methylurea-induced mammary tumors in rat. Anticancer research 20060101
The use of micronucleus test for detection of genotoxic damage to the thyroid gland. Bulletin of experimental biology and medicine 20060101
Tumor-protective and tumor-promoting actions of dietary whey proteins in an N-methyl-N-nitrosourea model of rat mammary carcinogenesis. Nutrition and cancer 20060101
Inhibition of carcinogen-induced DNA damage in rat liver and colon by garlic powders with varying alliin content. Nutrition and cancer 20060101
[Chemically methylated DNA repair in Escherichia coli--the role of alkB protein]. Postepy biochemii 20060101
Effects of different durations of estrogen and progesterone treatment on development of N-methyl-N-nitrosourea-induced mammary carcinomas in female Lewis rats. In vivo (Athens, Greece) 20060101
Celecoxib inhibits Cdx2 expression and prevents gastric cancer in Helicobacter pylori-infected Mongolian gerbils. Digestion 20060101
Enhancement by acrylamide of N-methyl-N-nitrosourea-induced rat mammary tumor development-possible application for a model to detect co-modifiers of carcinogenesis. Cancer letters 20051208
Helicobacter pylori-infected animal models are extremely suitable for the investigation of gastric carcinogenesis. World journal of gastroenterology 20051207
MNU-induced carcinogenesis of rat mammary gland: effect of thyroid hormone on expression of retinoic acid receptors in tumours of mammary gland. Molecular and cellular endocrinology 20051201
AT1 receptor and ACE mRNA are increased in chemically induced carcinoma of rat mammary gland. Molecular and cellular endocrinology 20051201
Endothelin B receptor agonist, IRL 1620, enhances the anti-tumor efficacy of paclitaxel in breast tumor rats. Breast cancer research and treatment 20051201
Fluorescence guided optical coherence tomography for the diagnosis of early bladder cancer in a rat model. The Journal of urology 20051201
Heme oxygenase-1 inhibits rat and human breast cancer cell proliferation: mutual cross inhibition with indoleamine 2,3-dioxygenase. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20051201
Prevention of N-methyl-N-nitrosourea-induced breast cancer by alpha-fetoprotein (AFP)-derived peptide, a peptide derived from the active site of AFP. Clinical cancer research : an official journal of the American Association for Cancer Research 20051201
Ploidy of micronucleated thyrocytes induced by methylnitrosourea injection. Bulletin of experimental biology and medicine 20051201
Sensitization of human carcinoma cells to alkylating agents by small interfering RNA suppression of 3-alkyladenine-DNA glycosylase. Cancer research 20051115
PARP-1-dependent 3-nitrotyrosine protein modification after DNA damage. Journal of cellular biochemistry 20051101
Methylguanine methyltransferase activity deficiency in immature rat mammary epithelial cells parallels increased carcinogenic susceptibility. Molecular carcinogenesis 20051101
[O6-benzylguanine stimulates regulatory functions of the Ada protein in Escherichia coli]. Genetika 20051101
Induced mutation spectra at the upp locus in Salmonella typhimurium: response of the target gene in the FU assay to mechanistically different mutagens. Mutation research 20051015
Chemoprevention of chemically-induced mammary and colon carcinogenesis by 1alpha-hydroxyvitamin D5. The Journal of steroid biochemistry and molecular biology 20051001
Optical biopsy of lymph node morphology using optical coherence tomography. Technology in cancer research & treatment 20051001
Regression of NMU-induced mammary tumors with the combination of melatonin and 9-cis-retinoic acid. Cancer letters 20050908
Effects of dietary folate on the development and progression of mammary tumors in rats. Carcinogenesis 20050901
Placental improvement and reduced distal limb defects by maternal interferon-gamma injection in methylnitrosourea-exposed mice. Birth defects research. Part A, Clinical and molecular teratology 20050901
Assessing susceptibility from early-life exposure to carcinogens. Environmental health perspectives 20050901
[Study of nutritional factors related to breast cancer prevention. Importance of animal models approaches]. Archivos latinoamericanos de nutricion 20050901
Effect of DNA polymerase beta loop variants on discrimination of O6-methyldeoxyguanosine modification present in the nucleotide versus template substrate. Biochemistry 20050802
Gene expression profiling of NMU-induced rat mammary tumors: cross species comparison with human breast cancer. Carcinogenesis 20050801
Different types of combination effects for the induction of micronuclei in mouse lymphoma cells by binary mixtures of the genotoxic agents MMS, MNU, and genistein. Toxicological sciences : an official journal of the Society of Toxicology 20050801
2-Deoxyglucose as an energy restriction mimetic agent: effects on mammary carcinogenesis and on mammary tumor cell growth in vitro. Cancer research 20050801
[Protective effects of ligustrazine against photoreceptor cell injury induced by N-methyl-N-nitrosourea and its mechanism]. Yao xue xue bao = Acta pharmaceutica Sinica 20050801
N-methyl-N-nitrosourea-induced apoptosis of photoreceptor cells in Sprague-Dawley rats via nuclear factor-kappaB. Chinese medical journal 20050705
Increased phospho-AKT is associated with loss of the androgen receptor during the progression of N-methyl-N-nitrosourea-induced prostate carcinogenesis in rats. The Prostate 20050701
Susceptibility of Lobund-Wistar x Copenhagen hybrid rats to autochthonous prostate carcinogenesis. The Prostate 20050701
Mammary glands of sexually immature rats are more susceptible than those of mature rats to the carcinogenic, lethal, and mutagenic effects of N-nitroso-N-methylurea. Molecular carcinogenesis 20050701
Hypermethylation patterns in the Fhit regulatory region are tissue specific. Molecular carcinogenesis 20050701
Tetramethylpyrazine protected photoreceptor cells of rats by modulating nuclear translocation of NF-kappaB. Acta pharmacologica Sinica 20050701
ET(B) receptor agonist, IRL 1620, does not affect paclitaxel plasma pharmacokinetics in breast tumour bearing rats. The Journal of pharmacy and pharmacology 20050701
Antioxidative and antigenotoxic effects of Japanese horse chestnut (Aesculus turbinata) seeds. The Journal of veterinary medical science 20050701
Metallothionein crypt-restricted immunopositivity indices (MTCRII) correlate with aberrant crypt foci (ACF) in mouse colon. British journal of cancer 20050620
Inhibition of NMU-induced mammary tumorigenesis by dietary soy. Cancer letters 20050616
Cooperative induction of rat mammary cancer by radiation and 1-methyl-1-nitrosourea via the oncogenic pathways involving c-Myc activation and H-ras mutation. International journal of cancer 20050610
Prevention of de novo prostate cancer by immunization with tumor-derived vaccines. Cancer immunology, immunotherapy : CII 20050601
Deficient MGMT and proficient hMLH1 expression renders gallbladder carcinoma cells sensitive to alkylating agents through G2-M cell cycle arrest. International journal of oncology 20050601
Chemopreventive effect of peroxisome proliferator-activated receptor gamma on gastric carcinogenesis in mice. Cancer research 20050601
[Characteristics of N-methyl-N-nitrosourea-induced retinal degeneration in animals and application for the therapy of human retinitis pigmentosa]. Nippon Ganka Gakkai zasshi 20050601
Inhibition of N-methyl-N-nitrosourea-induced mammary carcinogenesis by molecular iodine (I2) but not by iodide (I-) treatment Evidence that I2 prevents cancer promotion. Molecular and cellular endocrinology 20050531
Effect of perductal paclitaxel exposure on the development of MNU-induced mammary carcinoma in female S-D rats. Breast cancer research and treatment 20050501
The reactive D-glucopyranose moiety of streptozotocin is responsible for activation of macrophages and subsequent stimulation of CD8+ T cells. Chemical research in toxicology 20050501
[On antimutagenesis mechanism in plants]. Genetika 20050501
Role of Helicobacter pylori in gastric carcinogenesis: the origin of gastric cancers and heterotopic proliferative glands in Mongolian gerbils. Helicobacter 20050401
[Protective effect of non-mitogenic haFGF on retinal injury induced by N-methyl-N-nitrosourea in Sprague-Dawley rats]. Yao xue xue bao = Acta pharmaceutica Sinica 20050401
Effects of dietary energy repletion and IGF-1 infusion on the inhibition of mammary carcinogenesis by dietary energy restriction. Molecular carcinogenesis 20050301
Gene expression profiling of chemically induced rat mammary gland cancer. Carcinogenesis 20050201
Efficacy of Targretin on methylnitrosourea-induced mammary cancers: prevention and therapy dose-response curves and effects on proliferation and apoptosis. Carcinogenesis 20050201
Pyrrolidon carboxypeptidase activities in the hypothalamus-pituitary-thyroid and hypothalamus-pituitary-ovary axes of rats with mammary gland cancer induced by N-methyl nitrosourea. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20050201
Specific enkephalin-degrading aminopeptidase activity in the HPT and HPO axes of rats with breast cancer induced by N-methyl nitrosourea. Regulatory peptides 20050115
Differential adduction of proteins vs. deoxynucleosides by methyl methanesulfonate and 1-methyl-1-nitrosourea in vitro. Rapid communications in mass spectrometry : RCM 20050101
Inhibition by allyl sulfides and crushed garlic of O6-methylguanine formation in liver DNA of dimethylnitrosamine-treated rats. Nutrition and cancer 20050101
[The effect of oxidative stress on nitrosomethylurea-induced mutagenesis in sunflower Helianthus annuus L]. Genetika 20050101
Possible adjuvant cancer therapy by two prebiotics--inulin or oligofructose. In vivo (Athens, Greece) 20050101
Serum enkephalin-degrading aminopeptidase activity in N-methyl nitrosourea-induced rat breast cancer. Anticancer research 20050101
Alpha-tocopherol suppresses mammary tumor sensitivity to anthracyclines in fish oil-fed rats. Nutrition and cancer 20050101
Carboxyamido-triazole (CAI) reverses the balance between proliferation and apoptosis in a rat bladder cancer model. Anticancer research 20050101
Modulation of N-methyl-N-nitrosourea induced mammary tumors in Sprague-Dawley rats by combination of lysine, proline, arginine, ascorbic acid and green tea extract. Breast cancer research : BCR 20050101
Rapid in vivo Taxotere quantitative chemosensitivity response by 4.23 Tesla sodium MRI and histo-immunostaining features in N-Methyl-N-Nitrosourea induced breast tumors in rats. Cancer cell international 20050101
PCNA-MutSalpha-mediated binding of MutLalpha to replicative DNA with mismatched bases to induce apoptosis in human cells. Nucleic acids research 20050101
Epigenetics of cervical cancer. An overview and therapeutic perspectives. Molecular cancer 20050101
Total antioxidant status in the blood serum of rats exposed to N-nitroso compounds and nitric oxide synthase inhibitors. Roczniki Panstwowego Zakladu Higieny 20050101
Evaluation of the carcinogenic potential of clofibrate in the rasH2 mouse. International journal of toxicology 20050101
Studies evaluating the utility of N-methyl-N-nitrosourea as a positive control in carcinogenicity studies in the p53+/- mouse. International journal of toxicology 20050101
Insulin-like growth factor-I receptor expression and localization in benign and malignant rat mammary tumors. Anticancer research 20050101
Global gene expression profiling of chemically induced rat mammary gland carcinomas and adenomas. Toxicologic pathology 20050101
Effect of glibenclamide on N-nitroso-N-methylurea-induced mammary tumors in diabetic and nondiabetic rats. Oncology research 20050101
Antisense oligonucleotides targeting the progesterone receptor inhibit hormone-independent breast cancer growth in mice. Breast cancer research : BCR 20050101
Dehydroepiandrosterone inhibits the progression phase of mammary carcinogenesis by inducing cellular senescence via a p16-dependent but p53-independent mechanism. Breast cancer research : BCR 20050101
Selection of cell lines with enhanced invasive phenotype from xenografts of the human prostate cancer cell line WPE1-NB26. Journal of experimental therapeutics & oncology 20050101
[Mast cells of the mammary gland and of the regional lymph node in rats with breast cancer induced by N-methyl-N-nitrosourea]. Morfologiia (Saint Petersburg, Russia) 20050101
Neutrophil-mediated formation of carcinogenic N-nitroso compounds in an in vitro model for intestinal inflammation. Toxicology letters 20041230
The selective cyclooxygenase-2 inhibitor nimesulide prevents Helicobacter pylori-associated gastric cancer development in a mouse model. Clinical cancer research : an official journal of the American Association for Cancer Research 20041201
Animal models for the study of Helicobacter-induced gastric carcinoma. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20041201
[The toxic effect of N-methyl-N- nitrosourea on retina in rats]. Yan ke xue bao = Eye science 20041201
Alkylation damage in DNA and RNA--repair mechanisms and medical significance. DNA repair 20041102
Dietary effects of conjugated docosahexaenoic acid on N-methyl-N-nitrosourea-induced mammary carcinogenesis in female Sprague-Dawley rats. Oncology reports 20041101
Reduced birth defects caused by maternal immune stimulation in methylnitrosourea-exposed mice: association with placental improvement. Birth defects research. Part A, Clinical and molecular teratology 20041101
Frequent activation of CArG binding factor-A expression and binding in N-methyl-N-nitrosourea-induced rat mammary carcinomas. Breast cancer research and treatment 20041101
Synergistic effect of a retinoid X receptor-selective ligand bexarotene (LGD1069, Targretin) and paclitaxel (Taxol) in mammary carcinoma. Breast cancer research and treatment 20041101
Physiology and gene expression characteristics of carcinogen-initiated and tumor-transformed glial progenitor cells derived from the CNS of methylnitrosourea (MNU)-treated Sprague-Dawley rats. Journal of neuropathology and experimental neurology 20041101
Endothelin-1-induced vasodilatation in rat breast tumor is mediated through endothelin-B receptors. Journal of cardiovascular pharmacology 20041101
Antigenotoxic potential of glucomannan on four model test systems. Cell biology and toxicology 20041101
Low zinc intake suppressed N-methyl-N-nitrosourea-induced mammary tumorigenesis in Sprague-Dawley rats. Carcinogenesis 20041001
Inhibition of mammary gland tumors by short-term treatment of estradiol-3-benzoate associated with down-regulation of estrogen receptor ERalpha and ERbeta. Oncology reports 20041001
Stage-specific inhibition of mammary carcinogenesis by 1alpha-hydroxyvitamin D5. European journal of cancer (Oxford, England : 1990) 20041001
Mammary tumorigenesis in growth hormone deficient spontaneous dwarf rats; effects of hormonal treatments. Breast cancer research and treatment 20041001
Lack of effects of postnatal exposure to a mixture of aryl hydrocarbon-receptor agonists on the development of methylnitrosourea-induced mammary tumors in sprague-dawley rats. Journal of toxicology and environmental health. Part A 20040924
Decreased Helicobacter pylori associated gastric carcinogenesis in mice lacking inducible nitric oxide synthase. Gut 20040901
Effect of dietary energy restriction on vascular density during mammary carcinogenesis. Cancer research 20040815
Evaluation of co-stimulatory effects of Tamarindus indica L. on MNU-induced colonic cell proliferation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040801
Depletion of the 110-kilodalton isoform of poly(ADP-ribose) glycohydrolase increases sensitivity to genotoxic and endotoxic stress in mice. Molecular and cellular biology 20040801
Age-related differences in susceptibility to carcinogenesis: a quantitative analysis of empirical animal bioassay data. Environmental health perspectives 20040801
Transient adenoviral N-methylpurine DNA glycosylase overexpression imparts chemotherapeutic sensitivity to human breast cancer cells. Molecular cancer therapeutics 20040801
Serum oxytocinase activity is related to tumor growth parameters in N-methyl nitrosourea induced rat breast cancer. Life sciences 20040730
Role of IFN regulatory factor-1 and IL-12 in immunological resistance to pathogenesis of N-methyl-N-nitrosourea-induced T lymphoma. Journal of immunology (Baltimore, Md. : 1950) 20040715
Targeting angiogenesis for mammary cancer prevention: factors to consider in experimental design and analysis. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040701
DNA repair in hybrid fish of the genus Xiphophorus. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20040701
XPC lymphoblastoid cells defective in the hMutSalpha DNA mismatch repair complex exhibit normal sensitivity to UVC radiation and normal transcription-coupled excision repair of DNA cyclobutane pyrimidine dimers. DNA repair 20040603
Beta-catenin gene alteration in glandular stomach adenocarcinomas in N-methyl-N-nitrosourea-treated and Helicobacter pylori-infected Mongolian gerbils. Cancer science 20040601
Modulation of N-methyl-N-nitrosourea-induced crypt restricted metallothionein immunopositivity in mouse colon by a non-genotoxic diet-related chemical. Carcinogenesis 20040501
Diabetogenic effect of STZ diminishes with the loss of nitric oxide: role of ultraviolet light and carboxy-PTIO. Pharmacology 20040501
In vivo kinetics of micronuclei induction by bifunctional alkylating antineoplastics. Mutagenesis 20040501
Enhanced radiosensitivity of rat autochthonous mammary tumors by dietary docosahexaenoic acid. International journal of cancer 20040410
Re: Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. Journal of the National Cancer Institute 20040407
Complex effects of Ras proto-oncogenes in tumorigenesis. Carcinogenesis 20040401
Chemoprevention of cancer of the upper respiratory tract of the Syrian golden hamster by aerosol administration of difluoromethylornithine and 5-fluorouracil. Cancer research 20040401
Immuno-neutralization of circulating relaxin does not alter the breast cancer-protective action of parity in MNU-treated rats. Journal of experimental therapeutics & oncology 20040401
Generation of hydrogen peroxide and failure of antioxidative responses in pancreatic islets of male C57BL/6 mice are associated with diabetes induced by multiple low doses of streptozotocin. Diabetologia 20040401
The stroma as a crucial target in rat mammary gland carcinogenesis. Journal of cell science 20040315
Measurement of DNA single-strand breaks by alkaline elution and fluorometric DNA quantification. Analytical biochemistry 20040315
Watch thy neighbor: cancer is a communal affair. Journal of cell science 20040315
Effect of PSC 833, an inhibitor of P-glycoprotein on N-methyl-N-nitrosourea induced mammary carcinogenesis in rats. Carcinogenesis 20040301
Immunobiological characterization of N -nitrosomethylurea-induced rat breast carcinomas: tumoral IL-10 expression as a possible immune escape mechanism. Breast cancer research and treatment 20040301
Hypomethylation of DNA and the insulin-like growth factor-II gene in dichloroacetic and trichloroacetic acid-promoted mouse liver tumors. Toxicology 20040301
Training enhances vascular relaxation after chemotherapy-induced vasoconstriction. Medicine and science in sports and exercise 20040301
Downregulation of estrogen receptor alpha and beta expression in carcinogen-induced mammary gland tumors of rats. Eksperimental'naia onkologiia 20040301
Functional characterization of the bladder cancer marker, BLCA-4. Clinical cancer research : an official journal of the American Association for Cancer Research 20040215
Characterization of new estrogen receptor destabilizing compounds: effects on estrogen-sensitive and tamoxifen-resistant breast cancer. Journal of the National Cancer Institute 20040204
Dietary genistein results in larger MNU-induced, estrogen-dependent mammary tumors following ovariectomy of Sprague-Dawley rats. Carcinogenesis 20040201
Efficacy of 9-cis-retinoic acid and N-(4-hydroxyphenyl) retinamide alone and in combination in mammary cancer prevention. Oncology reports 20040201
Preventive effect of Juzen-taiho-to on endometrial carcinogenesis in mice is based on Shimotsu-to constituent. Biological & pharmaceutical bulletin 20040201
Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma. Cancer research 20040201
[Spontaneous and induced nitrosomethylurea reversion of plastomic chlorophyll mutants of the sunflower Helianthus annuus L]. Genetika 20040201
Chemically induced immunotoxicity in a medium-term multiorgan bioassay for carcinogenesis with Wistar rats. Toxicology and applied pharmacology 20040115
Generating mutations but providing chemosensitivity: the role of O6-methylguanine DNA methyltransferase in human cancer. Oncogene 20040108
The D5Mit7 locus on mouse chromosome 5 provides resistance to gamma-ray-induced but not N-methyl-N-nitrosourea-induced thymic lymphomas. Carcinogenesis 20040101
Prevention of mammary carcinogenesis by short-term estrogen and progestin treatments. Breast cancer research : BCR 20040101
Terminal endbuds and acini as the respective major targets for chemical and sporadic carcinogenesis in the mammary glands of human c-Ha-ras protooncogene transgenic rats. Breast cancer research and treatment 20040101
Suppression of N-methyl-N-nitrosourea-induced photoreceptor apoptosis in rats by docosahexaenoic acid. Ophthalmic research 20040101
Gliotoxin is a dual inhibitor of farnesyltransferase and geranylgeranyltransferase I with antitumor activity against breast cancer in vivo. Medical oncology (Northwood, London, England) 20040101
Plant sterols: factors affecting their efficacy and safety as functional food ingredients. Lipids in health and disease 20040101
Glutamyl- but not aspartyl-aminopeptidase activity is modified in serum of N-methyl nitrosourea-induced rat mammary tumours. Anticancer research 20040101
DNA damage processing and aberration formation in plants. Cytogenetic and genome research 20040101
[Chemoimmunotherapy with dacarbazine and aranose combined with interferon-alpha in disseminated cutaneous melanoma]. Voprosy onkologii 20040101
Estrogen receptor profiles: changes in mouse and rat mammary tumors by treatment with selective estrogen receptor modifiers. Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20040101
Insulin-like growth factor (IGF)-I obliterates the pregnancy-associated protection against mammary carcinogenesis in rats: evidence that IGF-I enhances cancer progression through estrogen receptor-alpha activation via the mitogen-activated protein kinase pathway. Breast cancer research : BCR 20040101
Final report of the amended safety assessment of PEG-5, -10, -16, -25, -30, and -40 soy sterol. International journal of toxicology 20040101
Effect of vanillin on toxicant-induced mutation and mitotic recombination in proliferating somatic cells of Drosophila melanogaster. Environmental and molecular mutagenesis 20040101
Location, location, location: regulation of breast cancer progression by the microenvironment. Breast cancer research : BCR 20040101
Infiltrating CD8+ T lymphocytes, natural killer cells, and expression of IL-10 and TGF-beta1 in chemically induced neoplasms in male Wistar rats. Toxicologic pathology 20040101
Effect of cytosine arabinoside and hydroxyurea on micronucleus formation induced by model clastogens in Chinese hamster V79 cells. Neoplasma 20040101
Effects of prepubertal zeranol exposure on estrogen target organs and N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats. In vivo (Athens, Greece) 20040101
N-Nitroso-N-methylurea. Report on carcinogens : carcinogen profiles 20040101
Chemoprevention of mammary carcinogenesis in female rats by rofecoxib. Cancer letters 20031230
Prepubertal resveratrol exposure accelerates N-methyl-N-nitrosourea-induced mammary carcinoma in female Sprague-Dawley rats. Cancer letters 20031230
Reduction of 1-methyl-1-nitrosourea-induced tumor burden with DNA vaccines encoding mutated ras epitopes and the costimulatory molecule B7.1. General physiology and biophysics 20031201
9cUAB30, an RXR specific retinoid, and/or tamoxifen in the prevention of methylnitrosourea-induced mammary cancers. Cancer letters 20031110
Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. Journal of the National Cancer Institute 20031105
Starch-branching enzyme I-deficient mutation specifically affects the structure and properties of starch in rice endosperm. Plant physiology 20031101
Telomere dysfunction results in enhanced organismal sensitivity to the alkylating agent N-methyl-N-nitrosourea. Cancer research 20031101
Subcutaneous undifferentiated sarcoma induced by N'-ethyl-N'-nitrosourea in rat: radiology, histopathology and mutagenesis. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20031101
Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis. DNA repair 20031007
Production of doubled haploids through anther culture of M1 rice plants derived from mutagenized fertilized egg cells. Plant cell reports 20031001
Changes in tumor vascularization after irradiation, anthracyclin, or antiangiogenic treatment in nitrosomethyl ureas-induced rat mammary tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 20031001
Apoptosis and mutation in the murine small intestine: loss of Mlh1- and Pms2-dependent apoptosis leads to increased mutation in vivo. DNA repair 20030918
Diethylsulphate and methylnitrosourea affect different targets in Chinese hamster fibroblasts: possible mechanisms of aneuploidy induction by these agents. Mutagenesis 20030901
Radiosensitivity of rat mammary tumors correlates with early vessel changes assessed by power Doppler sonography. Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 20030901
Chemomodulatory influence of Ferula asafoetida on mammary epithelial differentiation, hepatic drug metabolizing enzymes, antioxidant profiles and N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats. Breast cancer research and treatment 20030901
Treatment of 1-methyl-1-nitrosourea-induced mammary tumours with immunostimulatory CpG motifs and 13-cis retinoic acid in female rats: histopathological study. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030901
VIP grafted sterically stabilized liposomes for targeted imaging of breast cancer: in vivo studies. Journal of controlled release : official journal of the Controlled Release Society 20030828
Cadmium inhibits repair of UV-, methyl methanesulfonate- and N-methyl-N-nitrosourea-induced DNA damage in Chinese hamster ovary cells. Mutation research 20030828
Suppression of N-methyl-N-nitrosourea/testosterone-induced rat prostate cancer growth by celecoxib: effects on cyclooxygenase-2, cell cycle regulation, and apoptosis mechanism(s). Clinical cancer research : an official journal of the American Association for Cancer Research 20030815
Conformationally defined retinoic acid analogues. 5. Large-scale synthesis and mammary cancer chemopreventive activity for (2E,4E,6Z,8E)-8-(3',4'-dihydro-1'(2'H)-naphthalen-1'-ylidene)-3,7-dimethyl-2,4,6-octatrienoic acid (9cUAB30). Journal of medicinal chemistry 20030814
Dietary docosahexaenoic acid protects against N-methyl-N-nitrosourea-induced retinal degeneration in rats. Experimental eye research 20030801
Moderate exercise training slows mammary tumour growth in adolescent rats. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20030801
The D4Mit12 locus on mouse chromosome 4 provides susceptibility to both gamma-ray-induced and N-methyl-N-nitrosourea-induced thymic lymphomas. Cancer science 20030801
Evaluation of nonthreshold leukemogenic response to methyl nitrosourea in p53-deficient C3H/He mice. Toxicology and applied pharmacology 20030801
Development and characterization of DP-153, a nontumorigenic prostatic cell line that undergoes malignant transformation by expression of dominant-negative transforming growth factor beta receptor type II. Cancer research 20030801
Upregulation of cellular NF-kappa B activity by alkylating carcinogens in human epidermal keratinocytes. Biological & pharmaceutical bulletin 20030801
Serum pyrrolidone carboxypeptidase activity in N-methyl-nitrosourea induced rat breast cancer. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030801
Effects of Seocalcitol (EB1089) on nitrosomethyl urea-induced rat mammary tumors. Breast cancer research and treatment 20030801
Caspase-independent photoreceptor apoptosis in mouse models of retinal degeneration. The Journal of neuroscience : the official journal of the Society for Neuroscience 20030702
Mechanisms by which energy restriction inhibits rat mammary carcinogenesis: in vivo effects of corticosterone on cell cycle machinery in mammary carcinomas. Carcinogenesis 20030701
Prevention by intrarectal 5-aminosalicylic acid of N-methylnitrosourea-induced colon cancer in F344 rats. Diseases of the colon and rectum 20030701
Activity, pharmacokinetics and tissue distribution of TLC ELL-12 (liposomal antitumor ether lipid) in rats with transplantable, s.c. methylnitrosourea-induced tumors. Anti-cancer drugs 20030701
No involvement of beta-catenin gene mutation in gastric carcinomas induced by N-methyl-N-nitrosourea in male F344 rats. Cancer letters 20030610
An expression study of hormone receptors in spontaneously developed, carcinogen-induced and hormone-induced mammary tumors in female Noble rats. International journal of oncology 20030601
Structural and functional protection of photoreceptors from MNU-induced retinal degeneration by the X-linked inhibitor of apoptosis. Investigative ophthalmology & visual science 20030601
Zinc accumulation in N-methyl-N-nitrosourea-induced rat mammary tumors is accompanied by an altered expression of ZnT-1 and metallothionein. Experimental biology and medicine (Maywood, N.J.) 20030601
Induction of NAD(P)H quinone: oxidoreductase1 inhibits carcinogen-induced aberrant crypt foci in colons of Sprague-Dawley rats. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20030601
Functional rescue of N-methyl-N-nitrosourea-induced retinopathy by nicotinamide in Sprague-Dawley rats. Current eye research 20030601
Functional interaction between PARP-1 and PARP-2 in chromosome stability and embryonic development in mouse. The EMBO journal 20030501
Dietary folate deficiency suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats. Carcinogenesis 20030501
Effect of energy restriction on cell cycle machinery in 1-methyl-1-nitrosourea-induced mammary carcinomas in rats. Cancer research 20030315
Uptake of radiolabelled alpha-fetoprotein by experimental mammary adenocarcinoma and adenoma: in vivo and in vitro studies. Nuclear medicine communications 20030301
DNA repair protein MGMT protects against N-methyl-N-nitrosourea-induced conversion of benign into malignant tumors. Carcinogenesis 20030301
Effect of early eradication on Helicobacter pylori-related gastric carcinogenesis in Mongolian gerbils. Cancer science 20030301
Thymic lymphomas in Wistar rats exposed to N-methyl-N-nitrosourea (MNU). Cancer science 20030301
Analysis of altered gene expression profiles in retinoic acid or CpG-treated Sprague-Dawley rats with MNU-induced mammary adenocarcinoma by cDNA macro array. General physiology and biophysics 20030301
Chemoprevention of lung carcinogenesis by cacao liquor proanthocyanidins in a male rat multi-organ carcinogenesis model. Cancer letters 20030227
Spontaneous mammary tumors in aging Noble rats. International journal of oncology 20030201
Cell proliferation, apoptosis, and expression of cyclin D1 and cyclin E as potential biomarkers in tamoxifen-treated mammary tumors. Breast cancer research and treatment 20030201
Chemoprevention of Helicobacter pylori-associated gastric carcinogenesis in a mouse model: is it possible? Journal of biochemistry and molecular biology 20030131
Evidence for the involvement of ET(B) receptors in ET-1-induced changes in blood flow to the rat breast tumor. Cancer chemotherapy and pharmacology 20030101
Chemopreventive agents induce a senescence-like phenotype in rat mammary tumours. European journal of cancer (Oxford, England : 1990) 20030101
Splenic lymphocytes of adult Xenopus respond differentially to PMA in vitro by either dying or dividing: significance for cancer resistance in this species. Apoptosis : an international journal on programmed cell death 20030101
Chemical carcinogens induce varying patterns of LOH in mouse T-lymphocytes. Carcinogenesis 20030101
Suppression of mammary gland tumorigenesis in diabetic rats. Cancer detection and prevention 20030101
Chemoprevention of mammary carcinogenesis by 1alpha-hydroxyvitamin D5, a synthetic analog of Vitamin D. Mutation research 20030101
Effect of 2-methoxyestradiol on the growth of methyl-nitroso-urea (MNU)-induced rat mammary carcinoma. The Journal of steroid biochemistry and molecular biology 20030101
Differential gene expression in chemically induced mouse lung adenomas. Neoplasia (New York, N.Y.) 20030101
A noncarcinogenic small dose of n-methylnitrosourea enhances colon tumorigenesis in F344 rats. The Tohoku journal of experimental medicine 20030101
Genotoxic methylating agents modulate extracellular signal regulated kinase activity through MEK-dependent, glutathione-, and DNA methylation-independent mechanisms in lung epithelial cells. Chemical research in toxicology 20030101
G1 cell cycle regulatory proteins in chemically-induced rat mammary adenocarcinomas in vivo and tumor promotion-sensitive, -resistant and transformed mouse epidermal cells in vitro. Cell cycle (Georgetown, Tex.) 20030101
Interlaboratory comparison of short-term carcinogenicity studies using CB6F1-rasH2 transgenic mice. Toxicologic pathology 20030101
Comparison of the carcinogenic potential of streptozotocin by polarography and alkaline elution. Neoplasma 20030101
Pregnancy-induced changes in cell-fate in the mammary gland. Breast cancer research : BCR 20030101
Taenia crassiceps cysticercosis in mice does not increase the carcinogenic effect of methyl-nitrosourea. Experimental parasitology 20030101
Dietary purified cis-9,trans-11 conjugated linoleic acid isomer has anticarcinogenic properties in chemically induced mammary tumors in rats. Nutrition and cancer 20030101
Dietary docosahexaenoic acid suppresses N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats more effectively than eicosapentaenoic acid. Nutrition and cancer 20030101
Effect of prenatal and prepubertal genistein exposure on N-methyl-N-nitrosourea-induced mammary tumorigenesis in female Sprague-Dawley rats. In vivo (Athens, Greece) 20030101
Estradiol and progesterone can prevent rat mammary cancer when administered concomitantly with carcinogen but do not modify surviving tumor histology, estrogen receptor alpha status or Ha-ras mutation frequency. Anticancer research 20030101
Rapid emergence of mammary preneoplastic and malignant lesions in human c-Ha-ras proto-oncogene transgenic rats: possible application for screening of chemopreventive agents. Toxicologic pathology 20030101
Expression of biomarkers modulating prostate cancer angiogenesis: differential expression of annexin II in prostate carcinomas from India and USA. Molecular cancer 20030101
NMU-induced mammary carcinogenesis in female rats is influenced by repeated psychoemotional stress. Neoplasma 20030101
Prepubertal zearalenone exposure suppresses N-methyl-N-nitrosourea-induced mammary tumorigenesis but causes severe endocrine disruption in female Sprague-Dawley rats. Nutrition and cancer 20030101
XIAP protects photoreceptors from n-methyl-n-nitrosourea-induced retinal degeneration. Advances in experimental medicine and biology 20030101
Distinction of carcinogens from mutagens by induction of liver cell foci in a model for detection of initiation activity. Cancer letters 20021215
Lung tumorigenesis associated with erb-B-2 and erb-B-3 overexpression in human erb-B-3 transgenic mice is enhanced by methylnitrosourea. Oncogene 20021212
Resistance to mammary carcinogenesis in Copenhagen rats: potential roles of vascular endothelial growth factor and mast cells. Cancer letters 20021205
Dietary genistein suppresses chemically induced prostate cancer in Lobund-Wistar rats. Cancer letters 20021201
Earlier Helicobacter pylori infection increases the risk for the N-methyl-N-nitrosourea-induced stomach carcinogenesis in Mongolian gerbils. Japanese journal of cancer research : Gann 20021201
Effects of antioxidant 1-O-hexyl-2,3,5-trimethylhydroquinone or ascorbic acid on carcinogenesis induced by administration of aminopyrine and sodium nitrite in a rat multi-organ carcinogenesis model. Japanese journal of cancer research : Gann 20021201
Variable E-cadherin expression in a MNU-induced colon tumor model in rats which exposed with 50 Hz frequency sinusoidal magnetic field. The Tohoku journal of experimental medicine 20021201
Rapid induction of cataract by a single intraperitoneal administration of N-methyl-N-nitrosourea in 15-day-old Sprague-Dawley (Jcl: SD) rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20021101
Quantitative determination of N7-methyldeoxyguanosine and O6-methyldeoxyguanosine in DNA by LC-UV-MS-MS. Analytical chemistry 20021015
Cyclooxygenase-2 inhibitor celecoxib inhibits promotion of mammary tumorigenesis in rats fed a high fat diet rich in n-6 polyunsaturated fatty acids. Cancer letters 20021008
An experimental paradigm for studying the cellular and molecular mechanisms of cancer inhibition by energy restriction. Molecular carcinogenesis 20021001
Prevention and treatment of experimental breast cancer with the combination of a new selective estrogen receptor modulator, arzoxifene, and a new rexinoid, LG 100268. Clinical cancer research : an official journal of the American Association for Cancer Research 20021001
Interrelationships among angiogenesis, proliferation, and apoptosis in the tumor microenvironment during N-methyl-N-nitrosourea androgen-induced prostate carcinogenesis in rats. Carcinogenesis 20021001
Synergistic promoting effects of Helicobacter pylori infection and high-salt diet on gastric carcinogenesis in Mongolian gerbils. Japanese journal of cancer research : Gann 20021001
Inhibition of methylnitrosourea (MNU) induced oxidative stress and carcinogenesis by orally administered bee honey and Nigella grains in Sprague Dawely rats. Journal of experimental & clinical cancer research : CR 20020901
Effects of weaning by surrogate mothers (ACI) on tumor development in SD rats treated with methylnitrosourea (MNU) and/or N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). Hiroshima journal of medical sciences 20020901
Detection of cellular responses to toxicants by dielectrophoresis. Biochimica et biophysica acta 20020831
The ability to engage enterocyte apoptosis does not predict long-term crypt survival in p53 and Msh2 deficient mice. Oncogene 20020829
Pseudouridine, an antimutagenic substance in beer towards N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801
Preparation and biological evaluation of the new chlorin photosensitizer T3,4BCPC for detection and treatment of tumors. Journal of photochemistry and photobiology. B, Biology 20020801
Plant antimutagens and their mixtures in inhibition of genotoxic effects of xenobiotics and aging processes. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20020801
Centrosome amplification and overexpression of aurora A are early events in rat mammary carcinogenesis. Cancer research 20020715
Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes. Oncogene 20020711
Inhibitory effects of 17beta-estradiol and 4-n-octylphenol on 7,12-dimethylbenz[a]anthracene-induced mammary tumor development in human c-Ha-ras proto-oncogene transgenic rats. Carcinogenesis 20020701
Collaborative validation study of the in vivo micronucleus test using mouse colonic epithelial cells. Mutation research 20020627
Detection of mutation in transgenic CHO cells using green fluorescent protein as a reporter. Mutation research 20020627
Poly(ADP-ribose) polymerase-2 (PARP-2) is required for efficient base excision DNA repair in association with PARP-1 and XRCC1. The Journal of biological chemistry 20020621
Inactivation of O6-methylguanine-DNA methyltransferase by promoter CpG island hypermethylation in gastric cancers. British journal of cancer 20020617
Inhibitory effects of toremifene on N-methyl-N-nitrosourea and estradiol-17beta-induced endometrial carcinogenesis in mice. Japanese journal of cancer research : Gann 20020601
The growth hormone-deficient Spontaneous Dwarf rat is resistant to chemically induced mammary carcinogenesis. Carcinogenesis 20020601
Synergistic tumor promoter effects of estrone and progesterone in methylnitrosourea-induced rat mammary cancer. Cancer letters 20020528
Independent variation in susceptibilities of six different mouse strains to induction of pepsinogen-altered pyloric glands and gastric tumor intestinalization by N-methyl-N-nitrosourea. Cancer letters 20020528
A comparison of N-methyl-N-nitrosourea-induced chromatid aberrations and micronuclei in barley meristems using FISH techniques. Mutation research 20020527
Vascular density profile of rat mammary carcinomas induced by 1-methyl-1-nitrosourea: implications for the investigation of angiogenesis. Carcinogenesis 20020501
Effect of selective ablation of proliferating mammary epithelial cells on MNU induced rat mammary tumorigenesis. Breast cancer research and treatment 20020501
Thymosin alpha1 inhibits mammary carcinogenesis in Fisher rats. Peptides 20020501
Inulin/oligofructose and anticancer therapy. The British journal of nutrition 20020501
Induction of stem cell cycling in mice increases their sensitivity to a chemical leukaemogen: implications for inherited genomic instability and the bystander effect. Mutation research 20020425
Decreased susceptibility to NMU-induced mammary carcinogenesis in transgenic rats carrying multiple copies of a rat ras gene driven by the rat Harvey ras promoter. Oncogene 20020425
In vivo quantitation of tumour vascularisation assessed by Doppler sonography in rat mammary tumours. Ultrasound in medicine & biology 20020401
Selective depletion of human DNA-methyltransferase DNMT1 proteins by sulfonate-derived methylating agents. Cancer research 20020315
Ab initio GB study of methylation reaction of adenine, cytosine, guanine, and thymine by methanediazonium ion. Journal of theoretical biology 20020307
[Stimulated repopulation as a basis of antimutagenesis and the adaptive response in plants]. Genetika 20020301
Helicobacter pylori infection promotes gastric carcinogenesis in a mice model. Journal of gastroenterology and hepatology 20020301
Tumor prevention by 9-cis-retinoic acid in the N-nitroso-N-methylurea model of mammary carcinogenesis is potentiated by the pineal hormone melatonin. Breast cancer research and treatment 20020301
Nicotinamide prevents N-methyl-N-nitrosourea-induced photoreceptor cell apoptosis in Sprague-Dawley rats and C57BL mice. Experimental eye research 20020301
PARP-1 modifies the effectiveness of p53-mediated DNA damage response. Oncogene 20020207
Semi-automated method of quantifying vasculature of 1-methyl-1-nitrosourea-induced rat mammary carcinomas using immunohistochemical detection. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20020201
Tlag2, an N-methyl-N-nitrosourea susceptibility locus, maps to mouse chromosome 4. Molecular carcinogenesis 20020201
Helicobacter pylori does not promote N-methyl-N-nitrosourea-induced gastric carcinogenesis in SPF C57BL/6 mice. Japanese journal of cancer research : Gann 20020201
Chemoprevention of N-methylnitrosourea-induced colon carcinogenesis by ursodeoxycholic acid-5-aminosalicylic acid conjugate in F344 rats. Japanese journal of cancer research : Gann 20020201
The Polycomb-group gene eed regulates thymocyte differentiation and suppresses the development of carcinogen-induced T-cell lymphomas. Oncogene 20020110
Mammary carcinomas induced in human c-Ha-ras proto-oncogene transgenic rats are estrogen-independent, but responsive to d-limonene treatment. Japanese journal of cancer research : Gann 20020101
Ploidy differences between hormone- and chemical carcinogen-induced rat mammary neoplasms: comparison to invasive human ductal breast cancer. Molecular carcinogenesis 20020101
Prevention of methylnitrosourea-induced mammary cancers by 9-cis-retinoic acid and/or vitamin D3. Oncology reports 20020101
The inhibitory effect of octreotide on experimental colorectal carcinogenesis. Surgery today 20020101
Twenty-six-Week carcinogenicity study of chloroform in CB6F1 rasH2-transgenic mice. Toxicologic pathology 20020101
Body zinc distribution profile during N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats at various levels of dietary zinc intake. Biological trace element research 20020101
Suberoylanilide hydroxamic acid (SAHA), a histone deacetylase inhibitor, suppresses the growth of carcinogen-induced mammary tumors. Anticancer research 20020101
In vitro and in vivo effects of [Ni(M5FTSC)2Cl2] complex in cancer: preliminary tests. Anticancer research 20020101
Effects of glucose on cloning efficiency and mutagenesis of fetal rat cells. Teratogenesis, carcinogenesis, and mutagenesis 20020101
Adolescent vitamin A intake alters susceptibility to mammary carcinogenesis in the Sprague-Dawley rat. Nutrition and cancer 20020101
Nimesulide and melatonin in mammary carcinogenesis prevention in female Sprague-Dawley rats. Neoplasma 20020101
Antitumoral activity of a new series of 5,6-dihydrobenzo(a)carbazoles. Journal of experimental therapeutics & oncology 20020101
Evaluation of the antimutagenic activity of different vegetable extracts using an in vitro screening test. Proceedings of the Western Pharmacology Society 20020101
Conjugated linoleic acid isomers and mammary cancer prevention. Nutrition and cancer 20020101
Effects of body weight gain reduction resulting from chemopreventive agent treatment on mammary gland morphology. Nutrition and cancer 20020101
Lack of chemoprevention of indole-3-carbinol in N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats. IARC scientific publications 20020101
[Cytogenetic effect of temperature on the sunflower varieties]. Tsitologiia 20020101
N-Nitroso-N-methylurea. Report on carcinogens : carcinogen profiles 20020101
LAS, a novel selective estrogen receptor modulator with chemopreventive and therapeutic activity in the N-nitroso-N-methylurea-induced rat mammary tumor model. Cancer research 20011215
Identification of rat mammary tumor-1 gene (RMT-1), which is highly expressed in rat mammary tumors. Cancer letters 20011210
Chemoprevention of mammary, cervix and nervous system carcinogenesis in animals using cultured Panax ginseng drugs and preliminary clinical trials in patients with precancerous lesions of the esophagus and endometrium. Journal of Korean medical science 20011201
Growth and characterization of N-methyl-N-nitrosourea-induced mammary tumors in intact and ovariectomized rats. Carcinogenesis 20011201
[Mutagenic effect of nitrosomethylurea, modified by heat shock at early stages of sunflower seedling development]. Genetika 20011201
Mechanisms of hormonal prevention of breast cancer. Annals of the New York Academy of Sciences 20011201
Detection of tumorigenesis in rat bladders with optical coherence tomography. Medical physics 20011201
Effect of the aromatase inhibitor vorozole on estrogen and progesterone receptor content of rat mammary carcinomas induced by 1-methyl-1-nitrosourea. Breast cancer research and treatment 20011201
Effect of lactobacilli, bifidobacteria and inulin on the formation of aberrant crypt foci in rats. European journal of nutrition 20011201
Reduction of 1-methyl-1-nitrosourea-induced mammary gland carcinoma by in vivo application of immunostimulatory CpG motifs in Sprague-Dawley rats. General physiology and biophysics 20011201
Altered gene expression profile in chemically induced rat mammary adenocarcinomas and its modulation by an aromatase inhibitor. Oncogene 20011122
A technetium-99m-labelled cyclam acid porphyrin (CAP) for tumour imaging. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20011101
Overexpression of Ogt reduces MNU and ENU induced transition, but not transversion, mutations in E. coli. Mutation research 20011101
Transgenerational effects of preconception paternal contamination with (55)Fe. Radiation research 20011101
Organotropic chemopreventive effects of n-3 unsaturated fatty acids in a rat multi-organ carcinogenesis model. Japanese journal of cancer research : Gann 20011101
Effect of dietary zinc intake on N-methyl-N-nitrosourea-induced mammary tumorigenesis in rats. Biological trace element research 20011101
Estrogenic and antiestrogenic properties of resveratrol in mammary tumor models. Cancer research 20011015
Role of RAD51 in sister-chromatid exchanges in mammalian cells. Oncogene 20011004
Early exposure of the rat mammary gland to estrogen and progesterone blocks co-localization of estrogen receptor expression and proliferation. The Journal of endocrinology 20011001
Assessment of chronic toxicity and carcinogenicity in an accelerated cancer bioassay in rats of moxifloxacin, a quinolone antibiotic. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20011001
Para-aminobenzoic acid inhibits a set of SOS functions in Escherichia coli K12. Mutation research 20010920
Evaluation of the chemopreventive potential of retinoids using a novel in vitro human prostate carcinogenesis model. Mutation research 20010920
MMTV promoter hypomethylation is linked to spontaneous and MNU associated c-neu expression and mammary carcinogenesis in MMTV c-neu transgenic mice. Oncogene 20010920
Cell proliferation in cancer prevention; effects of preventive agents on estrogen-related endometrial carcinogenesis model and on an in vitro model in human colorectal cells. Mutation research 20010901
Effect of chloroform on dichloroacetic acid and trichloroacetic acid-induced hypomethylation and expression of the c-myc gene and on their promotion of liver and kidney tumors in mice. Carcinogenesis 20010901
MNU induction of neoplasia in a platyfish model. Laboratory investigation; a journal of technical methods and pathology 20010901
Mammary gland carcinoma-related increase of type I iodothyronine 5'-deiodinase activity in Sprague-Dawley rats. General physiology and biophysics 20010901
Overexpression of human O6-alkylguanine DNA alkyltransferase (AGT) prevents MNU induced lymphomas in heterozygous p53 deficient mice. Oncogene 20010830
Post-initiation treatment of Indole-3-carbinol did not suppress N-methyl-N-nitrosourea induced mammary carcinogenesis in rats. Cancer letters 20010828
Short-term exposure to estrogen and progesterone induces partial protection against N-nitroso-N-methylurea-induced mammary tumorigenesis in Wistar--Furth rats. Cancer letters 20010810
AP-1 mediated retinal photoreceptor apoptosis is independent of N-terminal phosphorylation of c-Jun. Cell death and differentiation 20010801
Proteome analysis of rat hepatomas: carcinogen-dependent tumor-associated protein variants. Electrophoresis 20010801
Chemoprevention of NMU-induced rat mammary carcinoma with the combination of melatonin and 9-cis-retinoic acid. Cancer letters 20010726
VIP receptors as molecular targets of breast cancer: implications for targeted imaging and drug delivery. Journal of controlled release : official journal of the Controlled Release Society 20010706
Differences in sensitivity of murine spermatogonia and somatic cells in vivo to sister-chromatid exchange induction by nitrosoureas. Mutation research 20010701
Parous rats regain high susceptibility to chemically induced mammary cancer after treatment with various mammotropic hormones. Carcinogenesis 20010701
Micronuclei and other nuclear lesions as genotoxicity indicators in rainbow trout Oncorhynchus mykiss. Ecotoxicology and environmental safety 20010701
Preventive effects of isoflavones, genistein and daidzein, on estradiol-17beta-related endometrial carcinogenesis in mice. Japanese journal of cancer research : Gann 20010701
Liver carcinogen aflatoxin B1 as an inducer of mitotic recombination in a human cell line. Molecular carcinogenesis 20010701
Modulatory effects of neonatal exposure to TCDD, or a mixture of PCBs, p,p'-DDT, and p-p'-DDE, on methylnitrosourea-induced mammary tumor development in the rat. Environmental health perspectives 20010701
The 3' --> 5' exonuclease of T4 DNA polymerase removes premutagenic alkyl mispairs and contributes to futile cycling at O6-methylguanine lesions. The Journal of biological chemistry 20010629
DNA damage and repair in Arabidopsis thaliana as measured by the comet assay after treatment with different classes of genotoxins. Mutation research 20010627
The comet assay detects adaptation to MNU-induced DNA damage in barley. Mutation research 20010627
Diesel exhaust-induced airway hyperresponsiveness in c-Ha-ras transgenic mice. Toxicology 20010621
Possible involvement of O6-methylguanine formation and p53 dysfunction in mouse urinary bladder carcinogenesis. Mutation research 20010602
High susceptibility of transgenic rats carrying the human c-Ha-ras proto-oncogene to chemically-induced mammary carcinogenesis. Mutation research 20010602
Dysfunction of Stat4 leads to accelerated incidence of chemical-induced thymic lymphomas in mice. Experimental and molecular pathology 20010601
Phytosterols have an unfavourable effect on bacterial activity and no evident protective effect on colon carcinogenesis. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20010601
Genetic analysis of neoplasia induced by N-nitroso-N-methylurea in Xiphophorus hybrid fish. Marine biotechnology (New York, N.Y.) 20010601
A proposed classification scheme for Xiphophorus melanomas based on histopathologic analyses. Marine biotechnology (New York, N.Y.) 20010601
The potential mechanism of the diabetogenic action of streptozotocin: inhibition of pancreatic beta-cell O-GlcNAc-selective N-acetyl-beta-D-glucosaminidase. The Biochemical journal 20010515
Twenty-six-week carcinogenicity study of sulfamethoxazole in CB6F1-Tg-rasH2 mice. The Journal of toxicological sciences 20010501
Preventive effects of Juzen-taiho-to on N-methyl-N-nitrosourea and estradiol-17beta-induced endometrial carcinogenesis in mice. Carcinogenesis 20010401
Characterization of initiated cells in N-methylnitrosourea-induced carcinogenesis of the CNS in the adult rat. Neuro-oncology 20010401
Human cell lines as an in vitro/in vivo model for prostate carcinogenesis and progression. The Prostate 20010401
Characterization of the biological activity of gamma-glutamyl-Se-methylselenocysteine: a novel, naturally occurring anticancer agent from garlic. Cancer research 20010401
Formation of N-nitroso-N-methylurea in various samples of smoked/dried fish, fish sauce, seafoods, and ethnic fermented/pickled vegetables following incubation with nitrite under acidic conditions. Journal of agricultural and food chemistry 20010401
Trichostatin A is a histone deacetylase inhibitor with potent antitumor activity against breast cancer in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research 20010401
Antitumoral effect of recombinant mistletoe lectin on chemically induced urinary bladder carcinogenesis in a rat model. Cancer 20010301
Role of N-methyl-N-nitrosourea in the induction of intestinal metaplasia and gastric adenocarcinoma in Mongolian gerbils infected with Helicobacter pylori. Scandinavian journal of gastroenterology 20010301
Chemically induced carcinogenesis: a comparison of 1-methyl-1-nitrosourea, 7,12-dimethylbenzanthracene,diethylnitroso-amine and azoxymethan models (minireview). Endocrine regulations 20010301
[Heat shock modification of nitrosomethylurea action on sunflower seedlings]. Genetika 20010301
Fluorometric determination of N-nitroso-N-methylurea with nicotinamide and acetophenone. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010301
Uridine uptake inhibition as a cytotoxicity test for a human hepatoma cell line (HepG2 cells): comparison with the neutral red assay. Toxicology 20010214
Protective role of medroxyprogesterone acetate on N-methyl-N-nitrosourea-induced lymphomas in BALB/c female mice. Leukemia research 20010201
[The role of Helicobacter pylori infection and effect of eradication in experimental animal models of gastric carcinogenesis]. Nihon rinsho. Japanese journal of clinical medicine 20010201
MGMT expression in murine bone marrow is a major determinant of animal survival after alkylating agent exposure. Journal of hematotherapy & stem cell research 20010201
Susceptibility of lean and obese Zucker rats to tumorigenesis induced by N-methyl-N-nitrosourea. Cancer letters 20010126
Endonuclease V of Escherichia coli prevents mutations from nitrosative deamination during nitrate/nitrite respiration. Mutation research 20010105
Molecular and genetic mechanisms of prostate cancer. Radiation research 20010101
Effects of vitamin D (calcitriol) on transitional cell carcinoma of the bladder in vitro and in vivo. The Journal of urology 20010101
Overexpression of human H-ras transgene is responsible for tumors induced by chemical carcinogens in mice. Oncology reports 20010101
Effects of acute and chronic body weight gain reductions in the evaluation of agents for efficacy in mammary cancer prevention. Oncology reports 20010101
The effect of short intermittent light exposures on the melatonin circadian rhythm and NMU-induced breast cancer in female F344/N rats. Toxicologic pathology 20010101
Effects of tamoxifen and melatonin on mammary gland cancer induced by N-methyl-N-nitrosourea and by 7,12-dimethylbenz(a)anthracene, respectively, in female Sprague-Dawley rats. Folia biologica 20010101
Differential expression of integrin mRNAs and proteins during normal rat mammary gland development and in carcinogenesis. Cell and tissue research 20010101
Detection of VIP receptors in MNU-induced breast cancer in rats: implications for breast cancer targeting. Breast cancer research and treatment 20010101
The impact of various suture materials on experimental colorectal carcinogenesis. Surgery today 20010101
Methylselenocysteine modulates proliferation and apoptosis biomarkers in premalignant lesions of the rat mammary gland. Anticancer research 20010101
Feeding thiol-containing compounds, derived from vegetables, fails to inhibit N-methylnitrosourea-induced mammary tumorigenesis. Cancer detection and prevention 20010101
CB6F1-rasH2 mouse: overview of available data. Toxicologic pathology 20010101
Preventive effects of raloxifene and melatonin in N-methyl-N-nitrosourea-induced mammary carcinogenesis in female rats. Neoplasma 20010101
The effects of microgravity on induced mutation in Escherichia coli and Saccharomyces cerevisiae. Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20010101
Alkylating agent (MNU)-induced mutation in space environment. Advances in space research : the official journal of the Committee on Space Research (COSPAR) 20010101
[Nitrosomethylurea -- 30 years of study and use in the treatment of cancer patients]. Voprosy onkologii 20010101
[Aranoza -- a new Russian antineoplastic drug]. Voprosy onkologii 20010101
[Production of potato cybrids without using genetic selection markers of the parental material: Solanum tuberosum L. plants (cv. Svitanok Kyivsky) with S. pinnatisectum Dun. plastids]. TSitologiia i genetika 20010101
Nonspecific stimulation of the maternal immune system. I. Effects On teratogen-induced fetal malformations. Teratology 20001201
Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin. Diabetologia 20001201
Consistent and fast inhibition of colon carcinogenesis by polyethylene glycol in mice and rats given various carcinogens. Cancer research 20000615
Role of DNA repair in carcinogen-induced ras mutation. Mutation research 20000530
In vivo administration of O(6)-benzylguanine does not influence apoptosis or mutation frequency following DNA damage in the murine intestine, but does inhibit P450-dependent activation of dacarbazine. Carcinogenesis 20000401
DNA repair: counteragent in mutagenesis and carcinogenesis-- accomplice in cancer therapy resistance. Mutation research 20000401
Toxicity, mutation frequency and mutation spectrum induced by dacarbazine in CHO cells expressing different levels of O(6)-methylguanine-DNA methyltransferase. Mutation research 20000214
Mechanisms of mutation induction in germ cells of the mouse as assessed by the specific locus test. Mutation research 19990716
Natural killer activity in a medium-term multi-organ bioassay for carcinogenesis. Japanese journal of cancer research : Gann 19990101
Glial tumors in the MNU rat model: induction of pure and mixed gliomas that do not require typical missense mutations of p53. Journal of neuropathology and experimental neurology 19981101
Effects of tamoxifen on endometrial carcinogenesis in mice. Japanese journal of cancer research : Gann 19980501
Studies of initiation and promotion of carcinogenesis by N-nitroso compounds. Cancer letters 19980130
Conformational change in human DNA repair enzyme O6-methylguanine-DNA methyltransferase upon alkylation of its active site by SN1 (indirect-acting) and SN2 (direct-acting) alkylating agents: breaking a 'salt-link'. Biochemistry 19960924
Expression of dynamin immunoreactivity in experimental pancreatic tumors induced in rat by mancozeb-nitrosomethylurea. Cancer letters 19960419
Phenobarbital promotes the development of adenocarcinomas in the accessory sex glands of MNU-inoculated L-W rats. Carcinogenesis 19951001
1 alpha,25-Dihydroxy-16-ene-23-yne-26,27-hexafluorocholecalciferol (Ro24-5531), a new deltanoid (vitamin D analogue) for prevention of breast cancer in the rat. Cancer research 19940401
Promoting effects of mancozeb on pancreas of nitrosomethylurea-treated rats. Carcinogenesis 19930501
Modifying influence of prior treatment with toxic agents on induction of preneoplastic and neoplastic lesions in a medium-term multi-organ carcinogenesis bioassay. Teratogenesis, carcinogenesis, and mutagenesis 19930101
EB1089: a new vitamin D analogue that inhibits the growth of breast cancer cells in vivo and in vitro. Biochemical pharmacology 19921215
Lack of synergism among DMAB, BOP, and MNU in induction of carcinomas of the rat ventral prostate. Teratogenesis, carcinogenesis, and mutagenesis 19920101
Changes of silver-stained nucleolar organizer regions in mouse endometrial carcinogenesis induced by N-methyl-N-nitrosourea and 17 beta-oestradiol. Virchows Archiv. A, Pathological anatomy and histopathology 19920101
Induction of invasive carcinomas of the seminal vesicles and coagulating glands of F344 rats by administration of N-methylnitrosourea or N-nitrosobis(2-oxopropyl)amine and followed by testosterone propionate with or without high-fat diet. Carcinogenesis 19911101
Different modifying responses of capsaicin in a wide-spectrum initiation model of F344 rat. Journal of Korean medical science 19910301
Comparison of the activity of topically applied pesticides and the herbicide 2,4-D in two short-term in vivo assays of genotoxicity in the mouse. Fundamental and applied toxicology : official journal of the Society of Toxicology 19901101
Characterization of an N-methyl-N-nitrosourea-induced autochthonous rat bladder cancer model. Cancer research 19901015
Characterization of adenocarcinomas of the dorsolateral prostate induced in Wistar rats by N-methyl-N-nitrosourea, 7,12-dimethylbenz(a)anthracene, and 3,2'-dimethyl-4-aminobiphenyl, following sequential treatment with cyproterone acetate and testosterone propionate. Cancer research 19900201
Induction of dorsolateral prostate adenocarcinomas and other accessory sex gland lesions in male Wistar rats by a single administration of N-methyl-N-nitrosourea, 7,12-dimethylbenz(a)anthracene, and 3,2'-dimethyl-4-aminobiphenyl after sequential treatment with cyproterone acetate and testosterone propionate. Cancer research 19900201
Experimental induction of neoplasia in the accessory sex organs of male Lobund-Wistar rats. Cancer research 19900101
Modifying effects of simultaneous treatment with butylated hydroxyanisole (BHA) on rat tumor induction by 3,2'-dimethyl-4-aminobiphenyl, 2,2'-dihydroxy-di-n-propylnitrosamine and N-methylnitrosourea. Carcinogenesis 19891201
Induction of altered hepatocellular foci of hamster for a possible short-term assay for carcinogens. Research communications in chemical pathology and pharmacology 19890301
Enhancement of methylnitrosourea-induced skin tumorigenesis and carcinogenesis in hairless mice by pretreatment with a mitosis-inhibiting epidermal pentapeptide. Carcinogenesis 19890201
Possible role for vitamin D in controlling breast cancer cell proliferation. Lancet (London, England) 19890128
Carcinogenesis in rats by nitrosodialkylureas containing methyl and ethyl groups given by gavage and in drinking water. Journal of toxicology and environmental health 19890101
Agent-specific ras oncogene activation in rat thyroid tumours. Oncogene 19881101
Specificity study to evaluate induction of aberrant crypts in murine colons. Cancer research 19881101
Effects of treatment with N-methyl-N-nitrosourea, artificial sweeteners, and cyclophosphamide on adult rat urinary bladder in vitro. Laboratory investigation; a journal of technical methods and pathology 19871001
Production of autochthonous prostate cancer in Lobund-Wistar rats by treatments with N-nitroso-N-methylurea and testosterone. Journal of the National Cancer Institute 19860801
The effects of dietary butylated hydroxytoluene on liver and colon tumor development in mice. Toxicology 19860201
Enhanced tumour development by butylated hydroxytoluene (BHT) in the liver, lung and gastro-intestinal tract. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19860101
N-Nitroso-N-methylurea initiation in multiple tissues for organ-specific tumor promotion in rats by phenobarbital. Journal of the National Cancer Institute 19851201
5-azacytidine potentiates initiation induced by carcinogens in rat liver. Carcinogenesis 19850101
Promoting activities of butylated hydroxyanisole, butylated hydroxytoluene and sodium L-ascorbate on forestomach and urinary bladder carcinogenesis initiated with methylnitrosourea in F344 male rats. Gan 19840901
Organ-specific promoting effect of phenobarbital and saccharin in induction of thyroid, liver, and urinary bladder tumors in rats after initiation with N-nitrosomethylurea. Cancer research 19830701
Modification of chemical carcinogenesis by antioxidants. Princess Takamatsu symposia 19830101
Rat bladder isograft model for focal carcinoma. The Journal of urology 19820901
The effect of single dose N-methyl-N-nitrosourea on bladder carcinogenesis by N-[4-(5-nitro-2-furyl)-2-thiazolyl] formamide in rats. Investigative urology 19810501
Effects of three retinoids on colon adenocarcinomas, sarcomas and hyperplastic polyps induced by intrarectal N-methyl-N-nitrosourea administration in male F344 rats. Carcinogenesis 19810101
Growth regulation of two rat adenocarcinoma cell lines by dexamethasone and progesterone. Breast cancer research and treatment 19810101
[Comparative effectiveness of different tests to determine the mutagenicity of certain factors in mammals. II. Frequency of anomalous sperm head in mice exposed to different factors]. Genetika 19800101
Prophylaxis of bladder tumor implantation. Intravesical and systemic chemotherapy. Urology 19760101
Susceptibility of urothelium to neoplastic cellular implantation. Urology 19750601
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