(3β)-Lanosta-8,24-dien-3-ol
| Title | Journal |
|---|---|
| Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway. | Chemico-biological interactions 20180625 |
| New Bioactive Semisynthetic Derivatives of 31-Norlanostenol and Obtusifoliol from Euphorbia officinarum. | Natural product communications 20160601 |
| Protective effect of ganodermanondiol isolated from the Lingzhi mushroom against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2-mediated antioxidant enzymes. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20130301 |
| Disorders of sterol synthesis: beyond Smith-Lemli-Opitz syndrome. | American journal of medical genetics. Part C, Seminars in medical genetics 20121115 |
| Gas chromatography-tandem mass spectrometry method for the simultaneous determination of oxysterols, plant sterols, and cholesterol precursors. | Clinical chemistry 20121101 |
| Protein engineering of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase into parkeol synthase. | Organic letters 20121019 |
| Lanosterol biosynthesis: the critical role of the methyl-29 group of 2,3-oxidosqualene for the correct folding of this substrate and for the construction of the five-membered D ring. | Chemistry (Weinheim an der Bergstrasse, Germany) 20121008 |
| Cloning of the lanosterol 14-α-demethylase ( ERG11 ) gene in Trichosporon asahii: a possible association between G453R amino acid substitution and azole resistance in T. asahii. | FEMS yeast research 20120901 |
| The origin of fetal sterols in second-trimester amniotic fluid: endogenous synthesis or maternal-fetal transport? | American journal of obstetrics and gynecology 20120901 |
| Evolutionarily conserved Delta(25(27))-olefin ergosterol biosynthesis pathway in the alga Chlamydomonas reinhardtii. | Journal of lipid research 20120801 |
| Brain isoprenoids farnesyl pyrophosphate and geranylgeranyl pyrophosphate are increased in aged mice. | Molecular neurobiology 20120801 |
| Flip-flop of steroids in phospholipid bilayers: effects of the chemical structure on transbilayer diffusion. | Journal of the American Chemical Society 20120725 |
| Hepatitis C virus selectively perturbs the distal cholesterol synthesis pathway in a genotype-specific manner. | Hepatology (Baltimore, Md.) 20120701 |
| A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma. | Journal of lipid research 20120701 |
| Substrate analog studies of the ω-regiospecificity of Mycobacterium tuberculosis cholesterol metabolizing cytochrome P450 enzymes CYP124A1, CYP125A1 and CYP142A1. | Bioorganic & medicinal chemistry 20120701 |
| Potential biological functions of cytochrome P450 reductase-dependent enzymes in small intestine: novel link to expression of major histocompatibility complex class II genes. | The Journal of biological chemistry 20120518 |
| HILIC quantification of oenotheralanosterol A and B from Oenothera biennis and their suppression of IL-6 and TNF-α expression in mouse macrophages. | Journal of ethnopharmacology 20120507 |
| 27-Hydroxycholesterol, does it exist? On the nomenclature and stereochemistry of 26-hydroxylated sterols. | Steroids 20120501 |
| Sterol C24-methyltransferase: Physio- and stereo-chemical features of the sterol C3 group required for catalytic competence. | Archives of biochemistry and biophysics 20120501 |
| [Triterpenoids from Inonotus obliquus protect mice against oxidative damage induced by CCl4]. | Yao xue xue bao = Acta pharmaceutica Sinica 20120501 |
| Cytotoxic and pro-apoptotic effects of novel ganoderic acid derivatives on human cervical cancer cells in vitro. | European journal of pharmacology 20120415 |
| Novel sterol metabolic network of Trypanosoma brucei procyclic and bloodstream forms. | The Biochemical journal 20120401 |
| Cell-cell transmission enables HIV-1 to evade inhibition by potent CD4bs directed antibodies. | PLoS pathogens 20120401 |
| Computational prediction of metabolism: sites, products, SAR, P450 enzyme dynamics, and mechanisms. | Journal of chemical information and modeling 20120326 |
| Simultaneous determination of cimicifugoside H-2, cimicifugoside H-1, 23-epi-26-deoxyactein, cimigenol xyloside and 25-O-acetylcimigenoside in beagle dog plasma by LC-MS/MS. | Journal of pharmaceutical and biomedical analysis 20120325 |
| The role of extracerebral cholesterol homeostasis and ApoE e4 in cognitive decline. | Neurobiology of aging 20120301 |
| Lanosterol induces mitochondrial uncoupling and protects dopaminergic neurons from cell death in a model for Parkinson's disease. | Cell death and differentiation 20120301 |
| Novel iron-sulfur containing NADPH-reductase from Nocardia farcinica IFM10152 and fusion construction with CYP51 lanosterol demethylase. | Biotechnology and bioengineering 20120301 |
| Enhanced recovery of antitumor ganoderic acid T from Ganoderma lucidum mycelia by novel chemical conversion strategy. | Biotechnology and bioengineering 20120301 |
| Differences in brain cholesterol metabolism and insulin in two subgroups of patients with different CSF biomarkers but similar white matter lesions suggest different pathogenic mechanisms. | Neuroscience letters 20120227 |
| Euphol prevents experimental autoimmune encephalomyelitis in mice: evidence for the underlying mechanisms. | Biochemical pharmacology 20120215 |
| Identification and potency of cyclodextrin-lipid inhibitors of Staphylococcus aureus α-toxin. | Current eye research 20120201 |
| Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Delta7-24, 25-dihydrolanosterol. | Journal of lipid research 20120201 |
| A novel role for α-tocopherol transfer protein (α-TTP) in protecting against chloroquine toxicity. | The Journal of biological chemistry 20120120 |
| Role of a disordered steroid metabolome in the elucidation of sterol and steroid biosynthesis. | Lipids 20120101 |
| Antifungal resistance and new strategies to control fungal infections. | International journal of microbiology 20120101 |
| Cholesterol synthesis is associated with hepatic lipid content and dependent on fructose/glucose intake in healthy humans. | Experimental diabetes research 20120101 |
| Consumption of oxygen: a mitochondrial-generated progression signal of advanced cancer. | Cell death & disease 20120101 |
| Aberrant phenotypes of transgenic mice expressing dimeric human erythropoietin. | Reproductive biology and endocrinology : RB&E 20120101 |
| Lateral transfer of tetrahymanol-synthesizing genes has allowed multiple diverse eukaryote lineages to independently adapt to environments without oxygen. | Biology direct 20120101 |
| Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter. | BMC genomics 20120101 |
| Novel insights into the downstream pathways and targets controlled by transcription factors CREM in the testis. | PloS one 20120101 |
| Chemosensitization as a means to augment commercial antifungal agents. | Frontiers in microbiology 20120101 |
| Triazole fungicides can induce cross-resistance to medical triazoles in Aspergillus fumigatus. | PloS one 20120101 |
| Antifungal susceptibility profiles of 1698 yeast reference strains revealing potential emerging human pathogens. | PloS one 20120101 |
| Characterization of the chromosome 4 genes that affect fluconazole-induced disomy formation in Cryptococcus neoformans. | PloS one 20120101 |
| CUP-1 is a novel protein involved in dietary cholesterol uptake in Caenorhabditis elegans. | PloS one 20120101 |
| Endoplasmic Reticulum Stress-Associated Lipid Droplet Formation and Type II Diabetes. | Biochemistry research international 20120101 |
| Sequence and analysis of the genome of the pathogenic yeast Candida orthopsilosis. | PloS one 20120101 |
| Identification and characterization of antifungal compounds using a Saccharomyces cerevisiae reporter bioassay. | PloS one 20120101 |
| Propiconazole is a specific and accessible brassinosteroid (BR) biosynthesis inhibitor for Arabidopsis and maize. | PloS one 20120101 |
| The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes. | PloS one 20120101 |
| Sterol lipid metabolism in down syndrome revisited: down syndrome is associated with a selective reduction in serum brassicasterol levels. | Current gerontology and geriatrics research 20120101 |
| Lipidomic analysis of extracellular vesicles from the pathogenic phase of Paracoccidioides brasiliensis. | PloS one 20120101 |
| Enhanced production of ganoderic acids and cytotoxicity of Ganoderma lucidum using solid-medium culture. | Bioscience, biotechnology, and biochemistry 20120101 |
| The yeast ABC transporter Pdr18 (ORF YNR070w) controls plasma membrane sterol composition, playing a role in multidrug resistance. | The Biochemical journal 20111201 |
| Metabolic link between phosphatidylethanolamine and triacylglycerol metabolism in the yeast Saccharomyces cerevisiae. | Biochimica et biophysica acta 20111201 |
| Effects of Ficus carica paste on constipation induced by a high-protein feed and movement restriction in beagles. | Laboratory animal research 20111201 |
| Semisynthesis and biological evaluation of ganodermanontriol and its stereoisomeric triols. | Journal of natural products 20111128 |
| Transitional forms between the three domains of life and evolutionary implications. | Proceedings. Biological sciences 20111122 |
| Ganodermanontriol (GDNT) exerts its effect on growth and invasiveness of breast cancer cells through the down-regulation of CDC20 and uPA. | Biochemical and biophysical research communications 20111118 |
| Synthesis, antifungal activity, and docking study of some new 1,2,4-triazole analogs. | Chemical biology & drug design 20111101 |
| Pathogenesis-based therapy reverses cutaneous abnormalities in an inherited disorder of distal cholesterol metabolism. | The Journal of investigative dermatology 20111101 |
| Deletion of Cryptococcus neoformans AIF ortholog promotes chromosome aneuploidy and fluconazole-resistance in a metacaspase-independent manner. | PLoS pathogens 20111101 |
| Biosynthesis of cholesterol and other sterols. | Chemical reviews 20111012 |
| Triterpenoids with neurotrophic activity from Ganoderma lucidum. | Natural product research 20111001 |
| Hepatic failure related to itraconazole use successfully treated by corticosteroids. | Hepatitis monthly 20111001 |
| Metabolically regulated endoplasmic reticulum-associated degradation of 3-hydroxy-3-methylglutaryl-CoA reductase: evidence for requirement of a geranylgeranylated protein. | The Journal of biological chemistry 20110916 |
| Do the substituent effects affect conformational freedom of squalene in hopene biosynthesis? | Journal of molecular modeling 20110901 |
| Cholesterol metabolism is required for intracellular hedgehog signal transduction in vivo. | PLoS genetics 20110901 |
| N-Cyclo-propyl-N-[2-(2,4-difluoro-phen-yl)-2-hy-droxy-1-(1H-1,2,4-triazol-1-yl)prop-yl]-2-(5-methyl-2,4-dioxo-1,2,3,4-tetra-hydro-pyrimidin-1-yl)acetamide dichloro-methane 0.62-solvate. | Acta crystallographica. Section E, Structure reports online 20110901 |
| Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome. | The Journal of biological chemistry 20110819 |
| Structure-based design, synthesis, and antifungal activity of new triazole derivatives. | Chemical biology & drug design 20110801 |
| Synthesis, in vitro evaluation and molecular docking studies of new triazole derivatives as antifungal agents. | Bioorganic & medicinal chemistry letters 20110801 |
| Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives. | European journal of medicinal chemistry 20110701 |
| p53 is important for the anti-invasion of ganoderic acid T in human carcinoma cells. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20110615 |
| Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice. | Plant foods for human nutrition (Dordrecht, Netherlands) 20110601 |
| The potentiality of medicinal plants as the source of new contraceptive principles in males. | North American journal of medical sciences 20110601 |
| Triterpene cyclases from Oryza sativa L.: cycloartenol, parkeol and achilleol B synthases. | Organic letters 20110520 |
| Whole body cholesterol metabolism is impaired in Huntington's disease. | Neuroscience letters 20110502 |
| Epigenetic alterations in liver of C57BL/6J mice after short-term inhalational exposure to 1,3-butadiene. | Environmental health perspectives 20110501 |
| Heterologous expression and characterization of the sterol 14α-demethylase CYP51F1 from Candida albicans. | Archives of biochemistry and biophysics 20110501 |
| Cdr2p contributes to fluconazole resistance in Candida dubliniensis clinical isolates. | Canadian journal of microbiology 20110501 |
| Cosegregation of aortic root atherosclerosis and intermediate lipid phenotypes on chromosomes 2 and 8 in an intercross of C57BL/6 and BALBc/ByJ low-density lipoprotein receptor-/- mice. | Arteriosclerosis, thrombosis, and vascular biology 20110401 |
| [Studies on the secondary metabolites of Coriolopsis sp. G066]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110401 |
| Sensitive and selective liquid chromatography-tandem mass spectrometry method for the determination of five ganoderic acids in Ganoderma lucidum and its related species. | Journal of pharmaceutical and biomedical analysis 20110325 |
| Pubertal presentation in seven patients with congenital adrenal hyperplasia due to P450 oxidoreductase deficiency. | The Journal of clinical endocrinology and metabolism 20110301 |
| Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ß-catenin signaling. | International journal of oncology 20110301 |
| Effects of inotodiol extracts from inonotus obliquus on proliferation cycle and apoptotic gene of human lung adenocarcinoma cell line A549. | Chinese journal of integrative medicine 20110301 |
| Mutation of isoleucine 705 of the oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae affects lanosterol's C/D-ring cyclization and 17α/β-exocyclic side chain stereochemistry. | Organic & biomolecular chemistry 20110221 |
| Autoregulation of cholesterol synthesis: physiologic and pathophysiologic consequences. | Steroids 20110201 |
| Functional expression and characterization of CYP51 from dandruff-causing Malassezia globosa. | FEMS yeast research 20110201 |
| Friedolanostane, friedocycloartane and benzophenone constituents of the bark and leaves of Garcinia benthami. | Phytochemistry 20110201 |
| Ultrastructural alterations induced by Δ(24(25))-sterol methyltransferase inhibitors on Trichomonas vaginalis. | FEMS microbiology letters 20110201 |
| Molecular modeling of human lanosterol 14α-demethylase complexes with substrates and their derivatives. | Biochemistry. Biokhimiia 20110201 |
| Cytosolic NADPH balancing in Penicillium chrysogenum cultivated on mixtures of glucose and ethanol. | Applied microbiology and biotechnology 20110101 |
| Inhibition of human sterol Δ7-reductase and other postlanosterol enzymes by LK-980, a novel inhibitor of cholesterol synthesis. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
| Two oxidosqualene cyclases responsible for biosynthesis of tomato fruit cuticular triterpenoids. | Plant physiology 20110101 |
| The evolution of farnesoid X, vitamin D, and pregnane X receptors: insights from the green-spotted pufferfish (Tetraodon nigriviridis) and other non-mammalian species. | BMC biochemistry 20110101 |
| Genome variation in Cryptococcus gattii, an emerging pathogen of immunocompetent hosts. | mBio 20110101 |
| Evaluation of the antibacterial and anticancer activities of some South African medicinal plants. | BMC complementary and alternative medicine 20110101 |
| Development of proteomics-based fungicides: new strategies for environmentally friendly control of fungal plant diseases. | International journal of molecular sciences 20110101 |
| Lipid pathway alterations in Parkinson's disease primary visual cortex. | PloS one 20110101 |
| The thermodynamics of simple biomembrane mimetic systems. | Journal of pharmacy & bioallied sciences 20110101 |
| Rapid isolation and purification of inotodiol and trametenolic acid from Inonotus obliquus by high-speed counter-current chromatography with evaporative light scatting detection. | Phytochemical analysis : PCA 20110101 |
| Pharmacology and metabolism of voriconazole and Posaconazole in the treatment of invasive aspergillosis: review of the literature. | European journal of medical research 20110101 |
| Epidemiology and antifungal resistance in invasive Aspergillosis according to primary disease: review of the literature. | European journal of medical research 20110101 |
| Impacts of membrane biophysics in Alzheimer's disease: from amyloid precursor protein processing to aβ Peptide-induced membrane changes. | International journal of Alzheimer's disease 20110101 |
| Comparative lipidomics of azole sensitive and resistant clinical isolates of Candida albicans reveals unexpected diversity in molecular lipid imprints. | PloS one 20110101 |
| Pneumocystis carinii sterol 14α-demethylase activity in Saccharomyces cerevisiae erg11 knockout mutant: sterol biochemistry. | The Journal of eukaryotic microbiology 20110101 |
| Expanding a dynamic flux balance model of yeast fermentation to genome-scale. | BMC systems biology 20110101 |
| Role of heme and heme-proteins in trypanosomatid essential metabolic pathways. | Enzyme research 20110101 |
| Synthesis, in vitro antifungal activity and mechanism of action of four sterol hydrazone analogues against the dimorphic fungus Paracoccidioides brasiliensis. | Steroids 20110101 |
| Cross-species discovery of syncretic drug combinations that potentiate the antifungal fluconazole. | Molecular systems biology 20110101 |
| Update on the optimal use of voriconazole for invasive fungal infections. | Infection and drug resistance 20110101 |
| Pathogenesis of the cutaneous phenotype in inherited disorders of cholesterol metabolism: Therapeutic implications for topical treatment of these disorders. | Dermato-endocrinology 20110101 |
| Amino acid substitutions at the major insertion loop of Candida albicans sterol 14alpha-demethylase are involved in fluconazole resistance. | PloS one 20110101 |
| Molecular modelling of the emergence of azole resistance in Mycosphaerella graminicola. | PloS one 20110101 |
| Multiple oxygen tension environments reveal diverse patterns of transcriptional regulation in primary astrocytes. | PloS one 20110101 |
| Characterization of the channel constriction allowing the access of the substrate to the active site of yeast oxidosqualene cyclase. | PloS one 20110101 |
| Metabolic alteration of urinary steroids in pre- and post-menopausal women, and men with papillary thyroid carcinoma. | BMC cancer 20110101 |
| Next generation sequencing provides rapid access to the genome of Puccinia striiformis f. sp. tritici, the causal agent of wheat stripe rust. | PloS one 20110101 |
| Analysis of hypoxia and hypoxia-like states through metabolite profiling. | PloS one 20110101 |
| TIGER: Toolbox for integrating genome-scale metabolic models, expression data, and transcriptional regulatory networks. | BMC systems biology 20110101 |
| The role of Candida albicans homologous recombination factors Rad54 and Rdh54 in DNA damage sensitivity. | BMC microbiology 20110101 |
| Synergistic inhibition of endothelial cell proliferation, tube formation, and sprouting by cyclosporin A and itraconazole. | PloS one 20110101 |
| Mechanism of resistance to dietary cholesterol. | Journal of lipids 20110101 |
| Genome-wide linkage scan of a pedigree with familial hypercholesterolemia suggests susceptibility loci on chromosomes 3q25-26 and 21q22. | PloS one 20110101 |
| Enteric microbiome metabolites correlate with response to simvastatin treatment. | PloS one 20110101 |
| Protein trafficking, ergosterol biosynthesis and membrane physics impact recombinant protein secretion in Pichia pastoris. | Microbial cell factories 20110101 |
| Preventive and therapeutic euphol treatment attenuates experimental colitis in mice. | PloS one 20110101 |
| Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis. | PloS one 20110101 |
| Oral itraconazole for the treatment of severe seborrhoeic dermatitis. | Indian journal of dermatology 20110101 |
| In vitro antitumor activity and structure characterization of ethanol extracts from wild and cultivated Chaga medicinal mushroom, Inonotus obliquus (Pers.:Fr.) Pilát (Aphyllophoromycetideae). | International journal of medicinal mushrooms 20110101 |
| Mathematical modeling and validation of the ergosterol pathway in Saccharomyces cerevisiae. | PloS one 20110101 |
| Triterpenoid biosynthesis and engineering in plants. | Frontiers in plant science 20110101 |
| Bioactivity-guided isolation of GABA(A) receptor modulating constituents from the rhizomes of Actaea racemosa. | Journal of natural products 20101227 |
| Separation and determination of four ganoderic acids from dried fermentation mycelia powder of Ganoderma lucidum by capillary zone electrophoresis. | Journal of pharmaceutical and biomedical analysis 20101215 |
| Current progress in the study on biosynthesis and regulation of ganoderic acids. | Applied microbiology and biotechnology 20101201 |
| Impact of atorvastatin and omega-3 ethyl esters 90 on plasma plant sterol concentrations and cholesterol synthesis in type 2 diabetes: a randomised placebo controlled factorial trial. | Atherosclerosis 20101201 |
| Biochemical research elucidating metabolic pathways in Pneumocystis. | Parasite (Paris, France) 20101201 |
| Divergent interactions involving the oxidosqualene cyclase and the steroid-3-ketoreductase in the sterol biosynthetic pathway of mammals and yeasts. | Biochimica et biophysica acta 20101101 |
| Hair and skin sterols in normal mice and those with deficient dehydrosterol reductase (DHCR7), the enzyme associated with Smith-Lemli-Opitz syndrome. | The Journal of steroid biochemistry and molecular biology 20101101 |
| Significance of protein elicitor isolated from Tuber melanosporum on the production of ganoderic acid and Ganoderma polysaccharides during the fermentation of Ganoderma lucidum. | Bioprocess and biosystems engineering 20101001 |
| Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. | Planta medica 20101001 |
| Cloning, mechanistic and functional analysis of a fungal sterol C24-methyltransferase implicated in brassicasterol biosynthesis. | Biochimica et biophysica acta 20101001 |
| Expression, purification, and characterization of Aspergillus fumigatus sterol 14-alpha demethylase (CYP51) isoenzymes A and B. | Antimicrobial agents and chemotherapy 20101001 |
| An unusual lanostane-type triterpenoid, spiroinonotsuoxodiol, and other triterpenoids from Inonotus obliquus. | Phytochemistry 20101001 |
| Targeting inflammatory pathways by triterpenoids for prevention and treatment of cancer. | Toxins 20101001 |
| Methyl jasmonate induces ganoderic acid biosynthesis in the basidiomycetous fungus Ganoderma lucidum. | Bioresource technology 20100901 |
| Observations on squalene accumulation in Saccharomyces cerevisiae due to the manipulation of HMG2 and ERG6. | FEMS yeast research 20100901 |
| Subcellular organelle lipidomics in TLR-4-activated macrophages. | Journal of lipid research 20100901 |
| Phytochemical investigation of the seeds of Althea officinalis L. | Natural product research 20100901 |
| Drug-induced regulation of target expression. | PLoS computational biology 20100901 |
| Azole drugs are imported by facilitated diffusion in Candida albicans and other pathogenic fungi. | PLoS pathogens 20100901 |
| Impact of oxygen level in gaseous phase on gene transcription and ganoderic acid biosynthesis in liquid static cultures of Ganoderma lucidum. | Bioprocess and biosystems engineering 20100801 |
| Adaptation of cholesterol synthesis to fasting and TNF-alpha: profiling cholesterol intermediates in the liver, brain, and testis. | The Journal of steroid biochemistry and molecular biology 20100801 |
| Alterations of cholesterol precursor levels in Alzheimer's disease. | Biochimica et biophysica acta 20100801 |
| A new ganoderic acid from Ganoderma lucidum mycelia. | Journal of Asian natural products research 20100801 |
| PKC signaling regulates drug resistance of the fungal pathogen Candida albicans via circuitry comprised of Mkc1, calcineurin, and Hsp90. | PLoS pathogens 20100801 |
| [Studies on the chemical constituents from the antithrombus activity extract of Radix Aerio Fici Microcarpae]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100801 |
| Abiesatrines A-J: anti-inflammatory and antitumor triterpenoids from Abies georgei Orr. | Organic & biomolecular chemistry 20100607 |
| Effects of FoxO4 overexpression on cholesterol biosynthesis, triacylglycerol accumulation, and glucose uptake. | Journal of lipid research 20100601 |
| Gonadotropin-regulated expressions of lanosterol 14alpha-demethylase, sterol Delta14-reductase and C-4 sterol methyl oxidase contribute to the accumulation of meiosis-activating sterol in rabbit gonads. | Prostaglandins & other lipid mediators 20100601 |
| The sterol methyltransferases SMT1, SMT2, and SMT3 influence Arabidopsis development through nonbrassinosteroid products. | Plant physiology 20100601 |
| Biotechnological production and application of ganoderic acids. | Applied microbiology and biotechnology 20100601 |
| Requirement for ergosterol in V-ATPase function underlies antifungal activity of azole drugs. | PLoS pathogens 20100601 |
| Anticancer activity of subfractions containing pure compounds of Chaga mushroom (Inonotus obliquus) extract in human cancer cells and in Balbc/c mice bearing Sarcoma-180 cells. | Nutrition research and practice 20100601 |
| Antiplasmodial lanostanes from the Ganoderma lucidum mushroom. | Journal of natural products 20100528 |
| Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery. | Journal of medicinal chemistry 20100527 |
| Identification of testosterone-dependent volatile compounds and proteins in the preputial gland of rat Rattus norvegicus. | General and comparative endocrinology 20100515 |
| Enhanced biosynthetic gene expressions and production of ganoderic acids in static liquid culture of Ganoderma lucidum under phenobarbital induction. | Applied microbiology and biotechnology 20100501 |
| Structure-based rational design, synthesis and antifungal activity of oxime-containing azole derivatives. | Bioorganic & medicinal chemistry letters 20100501 |
| Antifungal drug resistance: not all azoles are equal. | Expert review of anti-infective therapy 20100501 |
| Lipid metabolism and HCV infection. | Viruses 20100501 |
| Cloning and characterization of the lanosterol 14alpha-demethylase gene from Antrodia cinnamomea. | Journal of agricultural and food chemistry 20100428 |
| Lipotoxicity in obese pregnancy and its potential role in adverse pregnancy outcome and obesity in the offspring. | Clinical science (London, England : 1979) 20100428 |
| Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates. | ACS chemical biology 20100416 |
| Screening for amino acid substitutions in the Candida albicans Erg11 protein of azole-susceptible and azole-resistant clinical isolates: new substitutions and a review of the literature. | Diagnostic microbiology and infectious disease 20100401 |
| Structural characterization of CYP51 from Trypanosoma cruzi and Trypanosoma brucei bound to the antifungal drugs posaconazole and fluconazole. | PLoS neglected tropical diseases 20100401 |
| [RP-HPLC simultaneous determination of five triterpenoid acids in different parts of Poria cocos by UV wavelengths switch]. | Yao xue xue bao = Acta pharmaceutica Sinica 20100401 |
| Relationship between antifungal resistance of fluconazole resistant Candida albicans and mutations in ERG11 gene. | Chinese medical journal 20100305 |
| Improved model of lanosterol 14alpha-demethylase by ligand-supported homology modeling: validation by virtual screening and azole optimization. | ChemMedChem 20100301 |
| Lanostane triterpenes from the fruiting bodies of Ganoderma lucidum and their inhibitory effects on adipocyte differentiation in 3T3-L1 Cells. | Journal of natural products 20100226 |
| Effects of lanosterol on in vitro maturation of porcine oocytes. | Animal reproduction science 20100201 |
| Topical anti-inflammatory effect of tirucallol, a triterpene isolated from Euphorbia lactea latex. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20100201 |
| Antibacterial compounds from mushrooms I: a lanostane-type triterpene and prenylphenol derivatives from Jahnoporus hirtus and Albatrellus flettii and their activities against Bacillus cereus and Enterococcus faecalis. | Planta medica 20100201 |
| Ganoderic acids from Ganoderma lucidum: inhibitory activity of osteoclastic differentiation and structural criteria. | Planta medica 20100201 |
| Interactions of oxidosqualene cyclase (Erg7p) with 3-keto reductase (Erg27p) and other enzymes of sterol biosynthesis in yeast. | Biochimica et biophysica acta 20100201 |
| Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence. | PLoS pathogens 20100201 |
| Phytochemical characteristics and hypoglycaemic activity of fraction from mushroom Inonotus obliquus. | Journal of the science of food and agriculture 20100130 |
| Production of individual ganoderic acids and expression of biosynthetic genes in liquid static and shaking cultures of Ganoderma lucidum. | Applied microbiology and biotechnology 20100101 |
| Cholesterol, non-cholesterol sterols and bile acids in paediatric gallstones. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20100101 |
| Evolution of ergosterol biosynthesis inhibitors as fungicidal against Candida. | Microbial pathogenesis 20100101 |
| Changes in cholesterol biosynthetic and transport pathways after excitotoxicity. | Journal of neurochemistry 20100101 |
| Functional characterization and localization of Pneumocystis carinii lanosterol synthase. | Eukaryotic cell 20100101 |
| Protostadienol synthase from Aspergillus fumigatus: functional conversion into lanosterol synthase. | Biochemical and biophysical research communications 20100101 |
| Vitamin d levels and lipid response to atorvastatin. | International journal of endocrinology 20100101 |
| Functional characterization of the Chlamydomonas reinhardtii ERG3 ortholog, a gene involved in the biosynthesis of ergosterol. | PloS one 20100101 |
| Origin of the cell nucleus, mitosis and sex: roles of intracellular coevolution. | Biology direct 20100101 |
| Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine). | BMC genomics 20100101 |
| Identification and analysis of unitary pseudogenes: historic and contemporary gene losses in humans and other primates. | Genome biology 20100101 |
| Metabolomic analyses of plasma reveals new insights into asphyxia and resuscitation in pigs. | PloS one 20100101 |
| Anti-inflammatory effects of Inonotus obliquus in colitis induced by dextran sodium sulfate. | Journal of biomedicine & biotechnology 20100101 |
| Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis. | BMC genomics 20100101 |
| Ganoderic acid T inhibits tumor invasion in vitro and in vivo through inhibition of MMP expression. | Pharmacological reports : PR 20100101 |
| Development of azole resistance in Aspergillus fumigatus during azole therapy associated with change in virulence. | PloS one 20100101 |
| De novo sequencing and analysis of the American ginseng root transcriptome using a GS FLX Titanium platform to discover putative genes involved in ginsenoside biosynthesis. | BMC genomics 20100101 |
| Clinical utility of voriconazole eye drops in ophthalmic fungal keratitis. | Clinical ophthalmology (Auckland, N.Z.) 20100101 |
| Cellular cholesterol delivery, intracellular processing and utilization for biosynthesis of steroid hormones. | Nutrition & metabolism 20100101 |
| Phylogenetic distribution of fungal sterols. | PloS one 20100101 |
| Chemical combinations elucidate pathway interactions and regulation relevant to Hepatitis C replication. | Molecular systems biology 20100101 |
| Structural and functional study of YER067W, a new protein involved in yeast metabolism control and drug resistance. | PloS one 20100101 |
| Cholesterol induces specific spatial and orientational order in cholesterol/phospholipid membranes. | PloS one 20100101 |
| Antagonistic changes in sensitivity to antifungal drugs by mutations of an important ABC transporter gene in a fungal pathogen. | PloS one 20100101 |
| Liposomal amphotericin B and leishmaniasis: dose and response. | Journal of global infectious diseases 20100101 |
| Inhibition of iron uptake is responsible for differential sensitivity to V-ATPase inhibitors in several cancer cell lines. | PloS one 20100101 |
| Candida albicans virulence and drug-resistance requires the O-acyltransferase Gup1p. | BMC microbiology 20100101 |
| Lipid mediators in acne. | Mediators of inflammation 20100101 |
| Surface lipids as multifunctional mediators of skin responses to environmental stimuli. | Mediators of inflammation 20100101 |
| Identification and developmental expression of the full complement of Cytochrome P450 genes in Zebrafish. | BMC genomics 20100101 |
| Development, clinical utility, and place in therapy of posaconazole for prevention and treatment of invasive fungal infections. | Drug design, development and therapy 20100101 |
| Direct electrochemical analyses of human cytochromes b5 with a mutated heme pocket showed a good correlation between their midpoint and half wave potentials. | Journal of biomedical science 20100101 |
| Clearance in vivo of instilled [h]cholesterol from the rat lung. | Biochemistry research international 20100101 |
| Tumor and reproductive traits are linked by RNA metabolism genes in the mouse ovary: a transcriptome-phenotype association analysis. | BMC genomics 20100101 |
| Deciphering the nuclear bile acid receptor FXR paradigm. | Nuclear receptor signaling 20100101 |
| Management of tinea capitis in childhood. | Clinical, cosmetic and investigational dermatology 20100101 |
| Amelioration of lead-induced hepatotoxicity by Allium sativum extracts in Swiss albino mice. | The Libyan journal of medicine 20100101 |
| Role of posaconazole in the treatment of oropharyngeal candidiasis. | Infection and drug resistance 20100101 |
| Optimal management of oropharyngeal and esophageal candidiasis in patients living with HIV infection. | HIV/AIDS (Auckland, N.Z.) 20100101 |
| Phytopharmacology of Ficus religiosa. | Pharmacognosy reviews 20100101 |
| Lanostanes from Phellinus igniarius and their iNOS inhibitory activities. | Planta medica 20091201 |
| 13C nuclear magnetic resonance data of lanosterol derivatives--profiling the steric topology of the steroid skeleton via substituent effects on its 13C NMR. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20091201 |
| Design, synthesis, and antifungal activity of novel conformationally restricted triazole derivatives. | Archiv der Pharmazie 20091201 |
| Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: determination of a triterpenoid metabolic fingerprint for the in situ characterization of Ganoderma bioactive compounds. | Journal of separation science 20091201 |
| 4beta-hydroxycholesterol as a marker of CYP3A4 inhibition in vivo - effects of itraconazole in man. | International journal of clinical pharmacology and therapeutics 20091201 |
| Steroidal triterpenes: design of substrate-based inhibitors of ergosterol and sitosterol synthesis. | Molecules (Basel, Switzerland) 20091118 |
| Inhibition of nucleoside transport and synergistic potentiation of methotrexate cytotoxicity by cimicifugoside, a triterpenoid from Cimicifuga simplex. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20091105 |
| Reducing CYP51 inhibits follicle-stimulating hormone induced resumption of mouse oocyte meiosis in vitro. | Journal of lipid research 20091101 |
| Initiation of steroidogenesis precedes expression of cholesterologenic enzymes in the fetal mouse testes. | Anatomia, histologia, embryologia 20091101 |
| Dehydroeburicoic acid induces calcium- and calpain-dependent necrosis in human U87MG glioblastomas. | Chemical research in toxicology 20091101 |
| 24-Ethyl,24-methyl-29-nor-lanostanes from leaves of Freycinetia formosana. | Chemical & pharmaceutical bulletin 20091101 |
| Quantitative determination of steroids in the fruiting bodies and submerged-cultured mycelia of Inonotus obliquus. | Se pu = Chinese journal of chromatography 20091101 |
| Discovery of potent and reversible monoacylglycerol lipase inhibitors. | Chemistry & biology 20091030 |
| Discovery of highly potent novel antifungal azoles by structure-based rational design. | Bioorganic & medicinal chemistry letters 20091015 |
| Plasma levels of 24S-hydroxycholesterol reflect brain volumes in patients without objective cognitive impairment but not in those with Alzheimer's disease. | Neuroscience letters 20091002 |
| New azoles with potent antifungal activity: design, synthesis and molecular docking. | European journal of medicinal chemistry 20091001 |
| Anti-tumor-promoting effects of 25-methoxyporicoic acid A and other triterpene acids from Poria cocos. | Journal of natural products 20091001 |
| Acquisition of aneuploidy provides increased fitness during the evolution of antifungal drug resistance. | PLoS genetics 20091001 |
| Inhibition of cholesterol biosynthesis disrupts lipid raft/caveolae and affects insulin receptor activation in 3T3-L1 preadipocytes. | Biochimica et biophysica acta 20090901 |
| A comparison of the packing behavior of egg phosphatidylcholine with cholesterol and biogenically related sterols in Langmuir monolayer films. | Chemistry and physics of lipids 20090901 |
| Effects of triterpenoids from Poria cocos Wolf on the serotonin type 3A receptor-mediated ion current in Xenopus oocytes. | European journal of pharmacology 20090801 |
| Hsp90 orchestrates stress response signaling governing fungal drug resistance. | PLoS pathogens 20090801 |
| Exploring the effects of sterols in model lipid membranes using single-molecule orientations. | The journal of physical chemistry. B 20090730 |
| Combined gas chromatographic/mass spectrometric analysis of cholesterol precursors and plant sterols in cultured cells. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715 |
| Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum. | Journal of natural medicines 20090701 |
| Genomic analysis of the basal lineage fungus Rhizopus oryzae reveals a whole-genome duplication. | PLoS genetics 20090701 |
| Frequency and evolution of Azole resistance in Aspergillus fumigatus associated with treatment failure. | Emerging infectious diseases 20090701 |
| Hsp90 governs echinocandin resistance in the pathogenic yeast Candida albicans via calcineurin. | PLoS pathogens 20090701 |
| A new triterpene from the fruiting bodies of Ganoderma lucidum. | Yao xue xue bao = Acta pharmaceutica Sinica 20090701 |
| Structurally simple inhibitors of lanosterol 14alpha-demethylase are efficacious in a rodent model of acute Chagas disease. | Journal of medicinal chemistry 20090625 |
| Molecular oxygen activation and proton transfer mechanisms in lanosterol 14alpha-demethylase catalysis. | The journal of physical chemistry. B 20090611 |
| Polyporenic acid C induces caspase-8-mediated apoptosis in human lung cancer A549 cells. | Molecular carcinogenesis 20090601 |
| Age-dependent increase in desmosterol restores DRM formation and membrane-related functions in cholesterol-free DHCR24-/- mice. | Neurochemical research 20090601 |
| Sterol content analysis suggests altered eburicol 14alpha-demethylase (CYP51) activity in isolates of Mycosphaerella graminicola adapted to azole fungicides. | FEMS microbiology letters 20090601 |
| Cyclodextrin-modified capillary electrophoresis for achiral and chiral separation of ergostane and lanostane compounds extracted from the fruiting body of Antrodia camphorata. | Electrophoresis 20090601 |
| Lanosterol metabolic product(s) is involved in primordial folliculogenesis and establishment of primordial follicle pool in mouse fetal ovary. | Molecular reproduction and development 20090501 |
| Antiplasmodial and other constituents from four Indonesian Garcinia spp. | Phytochemistry 20090501 |
| Cytolethal distending toxin-induced cell cycle arrest of lymphocytes is dependent upon recognition and binding to cholesterol. | The Journal of biological chemistry 20090417 |
| The construction and characterization of self-sufficient lanosterol 14-demethylase fusion proteins consisting of yeast CYP51 and its reductase. | Biological & pharmaceutical bulletin 20090401 |
| Compound MMH01 possesses toxicity against human leukemia and pancreatic cancer cells. | Toxicology in vitro : an international journal published in association with BIBRA 20090401 |
| Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum. | Bioresource technology 20090301 |
| Modified oxidosqualene cyclases in the formation of bioactive secondary metabolites: biosynthesis of the antitumor clavaric acid. | Fungal genetics and biology : FG & B 20090301 |
| Drug interaction potential of 2-((3,4-dichlorophenethyl)(propyl)amino)-1-(pyridin-3-yl)ethanol (LK-935), the novel nonstatin-type cholesterol-lowering agent. | Drug metabolism and disposition: the biological fate of chemicals 20090201 |
| Trypanosoma cruzi CYP51 inhibitor derived from a Mycobacterium tuberculosis screen hit. | PLoS neglected tropical diseases 20090201 |
| Sterol 24-C-methyltransferase: an enzymatic target for the disruption of ergosterol biosynthesis and homeostasis in Cryptococcus neoformans. | Archives of biochemistry and biophysics 20090115 |
| The effect of plagiochin E alone and in combination with fluconazole on the ergosterol biosynthesis of Candida albicans. | Biological & pharmaceutical bulletin 20090101 |
| Characterization of sterol lipids in Kluyveromyces lactis strain M-16 accumulating a high amount of steryl glucoside. | Journal of oleo science 20090101 |
| Transcriptional profiling of the effects of 25-hydroxycholesterol on human hepatocyte metabolism and the antiviral state it conveys against the hepatitis C virus. | BMC chemical biology 20090101 |
| Revision of the absolute configuration at C(23) of lanostanoids and isolation of secondary metabolites from formosan soft coral Nephthea erecta. | Chemistry & biodiversity 20090101 |
| Sequential metabolism of 7-dehydrocholesterol to steroidal 5,7-dienes in adrenal glands and its biological implication in the skin. | PloS one 20090101 |
| Regulation of clock-controlled genes in mammals. | PloS one 20090101 |
| Influence of the cystic fibrosis transmembrane conductance regulator on expression of lipid metabolism-related genes in dendritic cells. | Respiratory research 20090101 |
| Growth inhibition and ultrastructural alterations induced by Delta24(25)-sterol methyltransferase inhibitors in Candida spp. isolates, including non-albicans organisms. | BMC microbiology 20090101 |
| Sterol metabolism in the oomycete Aphanomyces euteiches, a legume root pathogen. | The New phytologist 20090101 |
| LeishCyc: a biochemical pathways database for Leishmania major. | BMC systems biology 20090101 |
| Targeted suppression of heme oxygenase-1 by small interference RNAs inhibits the production of bilirubin in neonatal rat with hyperbilirubinemia. | BMC molecular biology 20090101 |
| Progressive obesity leads to altered ovarian gene expression in the Lethal Yellow mouse: a microarray study. | Journal of ovarian research 20090101 |
| Early development of Moniliophthora perniciosa basidiomata and developmentally regulated genes. | BMC microbiology 20090101 |
| Sterol Biosynthesis Pathway as Target for Anti-trypanosomatid Drugs. | Interdisciplinary perspectives on infectious diseases 20090101 |
| Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing. | BMC microbiology 20090101 |
| Management of invasive aspergillosis in patients with COPD: rational use of voriconazole. | International journal of chronic obstructive pulmonary disease 20090101 |
| Gene array analysis of adrenal glands in broiler chickens following ACTH treatment. | BMC genomics 20090101 |
| Transcriptional profiling of rats subjected to gestational undernourishment: implications for the developmental variations in metabolic traits. | PloS one 20090101 |
| Fixed drug eruption resulting from fluconazole use: a case report. | Journal of medical case reports 20090101 |
| Transcriptome analysis of differentiating trypanosomes reveals the existence of multiple post-transcriptional regulons. | BMC genomics 20090101 |
| Investigating the effects of statins on cellular lipid metabolism using a yeast expression system. | PloS one 20090101 |
| Phylogenomics of sterol synthesis: insights into the origin, evolution, and diversity of a key eukaryotic feature. | Genome biology and evolution 20090101 |
| Simultaneous HPLC determination of butenafine hydrochloride and betamethasone in a cream formulation. | Indian journal of pharmaceutical sciences 20090101 |
| Economic considerations in the treatment of invasive aspergillosis: a review of voriconazole pharmacoeconomic studies. | ClinicoEconomics and outcomes research : CEOR 20090101 |
| Elevated cholesterol precursors other than cholestanol can also be a hallmark for CTX. | Journal of inherited metabolic disease 20081201 |
| Lanostane-type triterpenes from the mushroom Astraeus pteridis with antituberculosis activity. | Journal of natural products 20081201 |
| Two novel A-seco-rearranged lanostane triterpenoids from Abies sachalinensis. | Archives of pharmacal research 20081201 |
| Loss of gamma-secretase function impairs endocytosis of lipoprotein particles and membrane cholesterol homeostasis. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20081112 |
| Importance of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase tyrosine 707 residue for chair-boat bicyclic ring formation and deprotonation reactions. | Organic letters 20081106 |
| Antifungal activity of 25-azalanosterol against Candida species. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20081101 |
| A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus. | PLoS pathogens 20081101 |
| Overexpression of human ABCG1 does not affect atherosclerosis in fat-fed ApoE-deficient mice. | Arteriosclerosis, thrombosis, and vascular biology 20081001 |
| Gas chromatographic-mass spectrometric analyses of cholesterol and its precursors in rat plasma as tert-butyldimethylsilyl derivatives. | Clinica chimica acta; international journal of clinical chemistry 20081001 |
| Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus. | Antimicrobial agents and chemotherapy 20081001 |
| Disruption of the gene encoding 3beta-hydroxysterol Delta-reductase (Tm7sf2) in mice does not impair cholesterol biosynthesis. | The FEBS journal 20081001 |
| Cytotoxic and anti-oxidant activities of lanostane-type triterpenes isolated from Poria cocos. | Chemical & pharmaceutical bulletin 20081001 |
| Regulation of cholesterologenesis by the oxysterol receptor, LXRalpha. | The Journal of biological chemistry 20080926 |
| Interfacial behavior of cholesterol, ergosterol, and lanosterol in mixtures with DPPC and DMPC. | Biophysical journal 20080901 |
| Multiple effects of a novel compound from Burkholderia cepacia against Candida albicans. | FEMS microbiology letters 20080801 |
| Posaconazole in the management of refractory invasive fungal infections. | Therapeutics and clinical risk management 20080801 |
| Spheciosterol sulfates, PKCzeta inhibitors from a philippine sponge Spheciospongia sp. | Journal of natural products 20080725 |
| Expression of microsomal lanosterol 14alpha-demethylase (CYP51) in an engineered soluble monomeric form. | Biochemical and biophysical research communications 20080711 |
| Nonenzymic polycyclization of analogues of oxidosqualene with a preformed C-ring. | Organic & biomolecular chemistry 20080607 |
| Cholesterol, lanosterol, and ergosterol attenuate the membrane association of LL-37(W27F) and temporin L. | Biochimica et biophysica acta 20080601 |
| Lanostane-type triterpenoids from the roots of Kadsura coccinea. | Journal of natural products 20080601 |
| Silencing of mouse hepatic lanosterol 14-alpha demethylase down-regulated plasma low-density lipoprotein cholesterol levels by short-term treatment of siRNA. | Biological & pharmaceutical bulletin 20080601 |
| Anti-HIV-1 protease activity of lanostane triterpenes from the vietnamese mushroom Ganoderma colossum. | Journal of natural products 20080601 |
| Characteristics of biofilm formation by Candida tropicalis and antifungal resistance. | FEMS yeast research 20080501 |
| Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. | International journal of molecular medicine 20080501 |
| ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080401 |
| Kadsuracoccinic acids A-C, ring-A seco-lanostane triterpenes from Kadsura coccinea and their effects on embryonic cell division of Xenopus laevis. | Journal of natural products 20080401 |
| Novel lanostane and rearranged lanostane-type triterpenoids from Abies sachalinensis - II -. | Chemical & pharmaceutical bulletin 20080401 |
| Oxysterols: novel biologic roles for the 21st century. | Steroids 20080201 |
| Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase. | The Journal of biological chemistry 20080118 |
| Moderately elevated plant sterol levels are associated with reduced cardiovascular risk--the LASA study. | Atherosclerosis 20080101 |
| Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51). | Bioorganic & medicinal chemistry 20080101 |
| Metabolic model integration of the bibliome, genome, metabolome and reactome of Aspergillus niger. | Molecular systems biology 20080101 |
| Novel role for SLPI in MOG-induced EAE revealed by spinal cord expression analysis. | Journal of neuroinflammation 20080101 |
| [Chemical constituents of the spores of Ganoderma lucidum]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080101 |
| Preservation of genes involved in sterol metabolism in cholesterol auxotrophs: facts and hypotheses. | PloS one 20080101 |
| Metabolic innovations towards the human lineage. | BMC evolutionary biology 20080101 |
| Altered bile acid metabolism in patients with constipation-predominant irritable bowel syndrome and functional constipation. | Scandinavian journal of gastroenterology 20080101 |
| Breast cancer proteomics reveals correlation between estrogen receptor status and differential phosphorylation of PGRMC1. | Breast cancer research : BCR 20080101 |
| Histone deacetylase inhibitors: a new mode for inhibition of cholesterol metabolism. | BMC genomics 20080101 |
| Expression and regulation of lanosterol 14alpha-demethylase in mouse embryo and uterus during the peri-implantation period. | Reproduction, fertility, and development 20080101 |
| Insulin-like growth factor-1 coordinately induces the expression of fatty acid and cholesterol biosynthetic genes in murine C2C12 myoblasts. | BMC genomics 20080101 |
| Dynamical modeling of the cholesterol regulatory pathway with Boolean networks. | BMC systems biology 20080101 |
| Inotodiol, a lanostane triterpenoid, from Inonotus obliquus inhibits cell proliferation through caspase-3-dependent apoptosis. | Anticancer research 20080101 |
| Monocytes of patients with familial hypercholesterolemia show alterations in cholesterol metabolism. | BMC medical genomics 20080101 |
| A novel three-stage light irradiation strategy in the submerged fermentation of medicinal mushroom Ganoderma lucidum for the efficient production of ganoderic acid and Ganoderma polysaccharides. | Biotechnology progress 20080101 |
| Antifungals: need to search for a new molecular target. | Indian journal of pharmaceutical sciences 20080101 |
| Hypolipidemia: a word of caution. | The Libyan journal of medicine 20080101 |
| Histone deacetylase 3 down-regulates cholesterol synthesis through repression of lanosterol synthase gene expression. | The Journal of biological chemistry 20071207 |
| cis-Acting elements within the Candida albicans ERG11 promoter mediate the azole response through transcription factor Upc2p. | Eukaryotic cell 20071201 |
| A squalene epoxidase is involved in biosynthesis of both the antitumor compound clavaric acid and sterols in the basidiomycete H. sublateritium. | Chemistry & biology 20071201 |
| Biosynthesis of phytosterol esters: identification of a sterol o-acyltransferase in Arabidopsis. | Plant physiology 20071101 |
| Synthesis and antifungal activities of novel 2-aminotetralin derivatives. | Journal of medicinal chemistry 20071101 |
| [Application of binding spectra in DMIs fungicide screening]. | Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20071101 |
| [Study on chemical constituents from rhizomes of Actaea asiatica]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101 |
| Progressive dysfunction of the cholesterol biosynthesis pathway in the R6/2 mouse model of Huntington's disease. | Neurobiology of disease 20071001 |
| Sterol biosynthesis by a prokaryote: first in vitro identification of the genes encoding squalene epoxidase and lanosterol synthase from Methylococcus capsulatus. | Bioscience, biotechnology, and biochemistry 20071001 |
| Hypoxia stimulates degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase through accumulation of lanosterol and hypoxia-inducible factor-mediated induction of insigs. | The Journal of biological chemistry 20070914 |
| The farnesoid X receptor FXRalpha/NR1H4 acquired ligand specificity for bile salts late in vertebrate evolution. | American journal of physiology. Regulatory, integrative and comparative physiology 20070901 |
| Structure elucidation and complete NMR spectral assignments of three new lanostanoid triterpenes with unprecedented Delta(16, 17) double bond from Ganoderma lucidum. | Magnetic resonance in chemistry : MRC 20070901 |
| Atorvastatin in patients with primary biliary cirrhosis and incomplete biochemical response to ursodeoxycholic acid. | Hepatology (Baltimore, Md.) 20070901 |
| 4-Methyl sterols regulate fission yeast SREBP-Scap under low oxygen and cell stress. | The Journal of biological chemistry 20070817 |
| Conformational dynamics in the F/G segment of CYP51 from Mycobacterium tuberculosis monitored by FRET. | Archives of biochemistry and biophysics 20070815 |
| Lanosterol biosynthesis in the prokaryote Methylococcus capsulatus: insight into the evolution of sterol biosynthesis. | Molecular biology and evolution 20070801 |
| Role of posaconazole in the management of oropharyngeal and esophageal candidiasis. | Therapeutics and clinical risk management 20070801 |
| Design, synthesis, and antifungal activities of novel 1H-triazole derivatives based on the structure of the active site of fungal lanosterol 14 alpha-demethylase (CYP51). | Chemistry & biodiversity 20070701 |
| Sterol composition in field-grown and cultured mycelia of Inonotus obliquus. | Yao xue xue bao = Acta pharmaceutica Sinica 20070701 |
| [Studies on the chemical constituents from herba anoectochili]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070701 |
| Regulation of hepatic Insig-2 by the farnesoid X receptor. | Molecular endocrinology (Baltimore, Md.) 20070601 |
| Enhancement of IL-2 and IFN-gamma expression and NK cells activity involved in the anti-tumor effect of ganoderic acid Me in vivo. | International immunopharmacology 20070601 |
| Electrochemical reduction of sterol-14alpha-demethylase from Mycobacterium tuberculosis (CYP51b1). | Biochemistry. Biokhimiia 20070601 |
| Diterpenoids and triterpenoids from Euphorbia guyoniana. | Phytochemistry 20070501 |
| Hepatic cytochrome P450 reductase-null mice reveal a second microsomal reductase for squalene monooxygenase. | Archives of biochemistry and biophysics 20070501 |
| Electrochemical properties of cytochroms P450 using nanostructured electrodes: direct electron transfer and electro catalysis. | Journal of inorganic biochemistry 20070501 |
| Rapid birth-death evolution specific to xenobiotic cytochrome P450 genes in vertebrates. | PLoS genetics 20070501 |
| Inhibition of angiogenesis by the antifungal drug itraconazole. | ACS chemical biology 20070424 |
| Structure of mixed micelles formed in PEG-lipid/lipid dispersions. | Langmuir : the ACS journal of surfaces and colloids 20070410 |
| Separation and determination of diversiform phytosterols in food materials using supercritical carbon dioxide extraction and ultraperformance liquid chromatography-atmospheric pressure chemical ionization-mass spectrometry. | Analytica chimica acta 20070404 |
| Cholesterol starvation induces differentiation of human leukemia HL-60 cells. | Cancer research 20070401 |
| [Study on chemical constituents of Euphorbia hylonoma hand. -Mazz]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070401 |
| Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. | Drug metabolism and disposition: the biological fate of chemicals 20070301 |
| Differential effects of cholesterol, ergosterol and lanosterol on a dipalmitoyl phosphatidylcholine membrane: a molecular dynamics simulation study. | The journal of physical chemistry. B 20070222 |
| Syntheses of ring C oxysterols: inhibitors of sterol biosynthesis. | Lipids 20070201 |
| Structure determination of inonotsuoxides A and B and in vivo anti-tumor promoting activity of inotodiol from the sclerotia of Inonotus obliquus. | Bioorganic & medicinal chemistry 20070101 |
| Amaranth oil application for coronary heart disease and hypertension. | Lipids in health and disease 20070101 |
| Preparative isolation of cyclolanostane-type saponins from Astragalus membranaceus bge. var. mongholicus (Bge.) Hsiao by TLC-MS/MS guided high-speed counter-current chromatography. | Journal of separation science 20070101 |
| The Interleukin-6 inflammation pathway from cholesterol to aging--role of statins, bisphosphonates and plant polyphenols in aging and age-related diseases. | Immunity & ageing : I & A 20070101 |
| Synthesis of the oxysterol, 24(S), 25-epoxycholesterol, parallels cholesterol production and may protect against cellular accumulation of newly-synthesized cholesterol. | Lipids in health and disease 20070101 |
| The transcriptome analysis of early morphogenesis in Paracoccidioides brasiliensis mycelium reveals novel and induced genes potentially associated to the dimorphic process. | BMC microbiology 20070101 |
| Transcriptome of Pneumocystis carinii during fulminate infection: carbohydrate metabolism and the concept of a compatible parasite. | PloS one 20070101 |
| Genomic analysis of the secretion stress response in the enzyme-producing cell factory Aspergillus niger. | BMC genomics 20070101 |
| Gene expression profiles in testis of pigs with extreme high and low levels of androstenone. | BMC genomics 20070101 |
| Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian cancer. | BMC cancer 20070101 |
| Photosensitivity in Smith-Lemli-Opitz syndrome: a flux balance analysis of altered metabolism. | Bioinformation 20070101 |
| Trametes versatillis, a fungus highly producing eburicoic acid. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101 |
| Separation of free sterols by high temperature liquid chromatography. | Journal of chromatography. A 20061229 |
| Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells. | Life sciences 20061223 |
| Comparison of lanosterol-14 alpha-demethylase (CYP51) of human and Candida albicans for inhibition by different antifungal azoles. | Toxicology 20061110 |
| Comparative calorimetric and spectroscopic studies of the effects of lanosterol and cholesterol on the thermotropic phase behavior and organization of dipalmitoylphosphatidylcholine bilayer membranes. | Biophysical journal 20061101 |
| Cloning of chicken lanosterol 14alpha-demethylase (CYP51) cDNA: discovery of a testis-specific CYP51 transcript. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20061101 |
| Design, synthesis, and antifungal activities in vitro of novel tetrahydroisoquinoline compounds based on the structure of lanosterol 14alpha-demethylase (CYP51) of fungi. | Bioorganic & medicinal chemistry letters 20061015 |
| Domain-formation in DOPC/SM bilayers studied by pfg-NMR: effect of sterol structure. | Biophysical journal 20061001 |
| Steroid structural requirements for interaction of ostreolysin, a lipid-raft binding cytolysin, with lipid monolayers and bilayers. | Biochimica et biophysica acta 20061001 |
| Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion. | International journal of molecular medicine 20061001 |
| Lanosterol 14alpha-demethylase expression in the mouse ovary and its participation in cumulus-enclosed oocyte spontaneous meiotic maturation in vitro. | Theriogenology 20060915 |
| New ganoderic acids, bioactive triterpenoid metabolites from the mushroom Ganoderma lucidum. | Natural product research 20060901 |
| Cholesterol precursors stabilize ordinary and ceramide-rich ordered lipid domains (lipid rafts) to different degrees. Implications for the Bloch hypothesis and sterol biosynthesis disorders. | The Journal of biological chemistry 20060804 |
| Synthetic studies toward highly functionalized 5beta-lanosterol derivatives: a versatile approach utilizing anionic cycloaddition. | The Journal of organic chemistry 20060804 |
| Cloning and characterization of CYP51 from Mycobacterium avium. | American journal of respiratory cell and molecular biology 20060801 |
| Phytosterol biosynthesis pathway in Mortierella alpina. | Phytochemistry 20060801 |
| Lanostane triterpenoids from the Sri Lankan basidiomycete Ganoderma applanatum. | Journal of natural products 20060801 |
| Cholesterol synthesis rate in human hippocampus declines with aging. | Neuroscience letters 20060731 |
| Sterol dependent regulation of human TM7SF2 gene expression: role of the encoded 3beta-hydroxysterol Delta14-reductase in human cholesterol biosynthesis. | Biochimica et biophysica acta 20060701 |
| Classical QSAR study on chromene derivatives as lanosterol 14alpha- demethylase inhibitor: a non azole antifungal target. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20060701 |
| Triadimefon causes branchial arch malformations in Xenopus laevis embryos. | Environmental science and pollution research international 20060701 |
| Puerarin decreases serum total cholesterol and enhances thoracic aorta endothelial nitric oxide synthase expression in diet-induced hypercholesterolemic rats. | Life sciences 20060620 |
| Influence of thermodynamic parameter in Lanosterol 14alpha-demethylase inhibitory activity as antifungal agents: a QSAR approach. | Biological & pharmaceutical bulletin 20060601 |
| Host-specific response to HCV infection in the chimeric SCID-beige/Alb-uPA mouse model: role of the innate antiviral immune response. | PLoS pathogens 20060601 |
| Voriconazole in the management of nosocomial invasive fungal infections. | Therapeutics and clinical risk management 20060601 |
| Site-saturated mutagenesis of histidine 234 of Saccharomyces cerevisiae oxidosqualene-lanosterol cyclase demonstrates dual functions in cyclization and rearrangement reactions. | Journal of the American Chemical Society 20060517 |
| Phase behavior of lipid monolayers containing DPPC and cholesterol analogs. | Biophysical journal 20060501 |
| Plant lanosterol synthase: divergence of the sterol and triterpene biosynthetic pathways in eukaryotes. | Plant & cell physiology 20060501 |
| Lanosterol synthase in dicotyledonous plants. | Plant & cell physiology 20060501 |
| [Studies on constituents from roots of Euphorbia hylonoma]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20060501 |
| Meiosis activating sterol (MAS) regulate FSH-induced meiotic resumption of cumulus cell-enclosed porcine oocytes via PKC pathway. | Molecular and cellular endocrinology 20060425 |
| Follicular sterol composition in gonadotrophin stimulated women with polycystic ovarian syndrome. | Molecular and cellular endocrinology 20060425 |
| Cimicifuga species identification by high performance liquid chromatography-photodiode array/mass spectrometric/evaporative light scattering detection for quality control of black cohosh products. | Journal of chromatography. A 20060421 |
| Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking. | Journal of medicinal chemistry 20060420 |
| Tryptophan 232 within oxidosqualene-lanosterol cyclase from Saccharomyces cerevisiae influences rearrangement and deprotonation but not cyclization reactions. | Organic letters 20060330 |
| Modulation of cholesterol metabolism by the green tea polyphenol (-)-epigallocatechin gallate in cultured human liver (HepG2) cells. | Journal of agricultural and food chemistry 20060308 |
| Universal behavior of membranes with sterols. | Biophysical journal 20060301 |
| Lanosterol biosynthesis in plants. | Archives of biochemistry and biophysics 20060301 |
| cDNA cloning, genomic structure and expression analysis of the bovine lanosterol 14alpha-demethylase (CYP51) in gonads. | Biological & pharmaceutical bulletin 20060301 |
| Mechanistic insights into triterpene synthesis from quantum mechanical calculations. Detection of systematic errors in B3LYP cyclization energies. | Organic & biomolecular chemistry 20060207 |
| Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20060201 |
| Cytotoxicity of cycloartane triterpenoids from aerial part of Cimicifuga foetida. | Fitoterapia 20060101 |
| Investigation of de novo cholesterol synthetic capacity in the gonads of goldfish (Carassius auratus) exposed to the phytosterol beta-sitosterol. | Reproductive biology and endocrinology : RB&E 20060101 |
| [Nanoelectrochemistry of cytochrome P450s: direct electron transfer and electrocatalysis]. | Biomeditsinskaia khimiia 20060101 |
| Bilayer thickness and thermal response of dimyristoylphosphatidylcholine unilamellar vesicles containing cholesterol, ergosterol and lanosterol: a small-angle neutron scattering study. | Biochimica et biophysica acta 20051230 |
| Cholesterogenic lanosterol 14alpha-demethylase (CYP51) is an immediate early response gene. | Endocrinology 20051201 |
| A new cytotoxic lanostane triterpenoid from the basidiomycete Hebeloma versipelle. | The Journal of antibiotics 20051201 |
| Sterol profiling of amniotic fluid: a routine method for the detection of distal cholesterol synthesis deficit. | Prenatal diagnosis 20051101 |
| Enzyme redesign: two mutations cooperate to convert cycloartenol synthase into an accurate lanosterol synthase. | Journal of the American Chemical Society 20051019 |
| A molecular mechanics force field for biologically important sterols. | Journal of computational chemistry 20051001 |
| Diffusion of cholesterol and its precursors in lipid membranes studied by 1H pulsed field gradient magic angle spinning NMR. | Biophysical journal 20051001 |
| Lipid signaling in plants. Cloning and expression analysis of the obtusifoliol 14alpha-demethylase from Solanum chacoense Bitt., a pollination- and fertilization-induced gene with both obtusifoliol and lanosterol demethylase activity. | Plant physiology 20051001 |
| Reductions in cholesterol and synaptic markers in association cortex in mood disorders. | Bipolar disorders 20051001 |
| Sterol structure determines miscibility versus melting transitions in lipid vesicles. | Biophysical journal 20050901 |
| The protein farnesyltransferase inhibitor Tipifarnib as a new lead for the development of drugs against Chagas disease. | Journal of medicinal chemistry 20050825 |
| Fluconazole upregulates sconC expression and inhibits sulphur metabolism in Microsporum canis. | Fungal genetics and biology : FG & B 20050801 |
| A prospective, randomized, double-blind, placebo-controlled study of the platelet and global hemostatic effects of Ganoderma lucidum (Ling-Zhi) in healthy volunteers. | Anesthesia and analgesia 20050801 |
| In vitro antifungal activity of ZJ-522, a new triazole restructured from fluconazole and butenafine, against clinically important fungi in comparison with fluconazole and butenafine. | Biological & pharmaceutical bulletin 20050801 |
| Friedolanostanes and lanostanes from the leaves of Garcinia hombroniana. | Journal of natural products 20050801 |
| Norlanostane triterpenoidal saponins from the marine sponge melophlussarassinorum. | Journal of natural products 20050801 |
| [Studies on chemical constitutes of green alga Chaetomorpha basiretorsa and their bioactivity]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050801 |
| Flux of sterol intermediates in a yeast strain deleted of the lanosterol C-14 demethylase Erg11p. | Biochimica et biophysica acta 20050715 |
| Cytochrome P450 17alpha hydroxylase/17,20 lyase (CYP17) function in cholesterol biosynthesis: identification of squalene monooxygenase (epoxidase) activity associated with CYP17 in Leydig cells. | Molecular endocrinology (Baltimore, Md.) 20050701 |
| Ganoderic acid Sz, a new lanostanoid from the mushroom Ganoderma lucidum. | Natural product research 20050701 |
| Lord of the rings--the mechanism for oxidosqualene:lanosterol cyclase becomes crystal clear. | Trends in pharmacological sciences 20050701 |
| Synthetic lanostane-type triterpenoids as inhibitors of DNA topoisomerase II. | Bioorganic & medicinal chemistry letters 20050615 |
| Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells. | Life sciences 20050603 |
| N-Phenethylhexadecanamide from the edible mushroom Laetiporus sulphureus. | Natural product research 20050601 |
| Cytotoxic constituents of the fruit body of Daedalea dickisii. | Journal of natural products 20050601 |
| Sterol stringency of proliferation and cell cycle progression in human cells. | Biochimica et biophysica acta 20050515 |
| Differences in the modulation of collective membrane motions by ergosterol, lanosterol, and cholesterol: a dynamic light scattering study. | Biophysical journal 20050501 |
| Pre-cholesterol precursors in gametogenesis. | Molecular and cellular endocrinology 20050429 |
| The imidazoline-like drug S23515 affects lipid metabolism in hepatocyte by inhibiting the oxidosqualene: lanosterol cyclase activity. | Biochemical pharmacology 20050401 |
| Determination of sterols in biological samples by SPME with on-fiber derivatization and GC/FID. | Analytical and bioanalytical chemistry 20050401 |
| Oxygenated lanostane-type triterpenoids from the fungus ganodermalucidum. | Journal of natural products 20050401 |
| How low can you go? | Science of aging knowledge environment : SAGE KE 20050316 |
| Desmosterol may replace cholesterol in lipid membranes. | Biophysical journal 20050301 |
| Dual-action hypoglycemic and hypocholesterolemic agents that inhibit glycogen phosphorylase and lanosterol demethylase. | Journal of lipid research 20050301 |
| Isotopomer spectral analysis of intermediates of cholesterol synthesis in patients with cerebrotendinous xanthomatosis. | Metabolism: clinical and experimental 20050301 |
| Insig-mediated degradation of HMG CoA reductase stimulated by lanosterol, an intermediate in the synthesis of cholesterol. | Cell metabolism 20050301 |
| Cancer preventive agents. Part 1: chemopreventive potential of cimigenol, cimigenol-3,15-dione, and related compounds. | Bioorganic & medicinal chemistry 20050215 |
| Antiproliferative synergism of azasterols and antifolates against Toxoplasma gondii. | International journal of antimicrobial agents 20050201 |
| The combination effects of phenolic compounds and fluconazole on the formation of ergosterol in Candida albicans determined by high-performance liquid chromatography/tandem mass spectrometry. | Analytical biochemistry 20050101 |
| Multidrug resistance in yeast Candida. | International review of cytology 20050101 |
| Aspergillus oryzae produces compounds inhibiting cholesterol biosynthesis downstream of dihydrolanosterol. | FEMS microbiology letters 20050101 |
| Lanostane triterpenoids and triterpene glycosides from the fruit body of Fomitopsis pinicola and their inhibitory activity against COX-1 and COX-2. | Journal of natural products 20050101 |
| MT FdR: a ferredoxin reductase from M. tuberculosis that couples to MT CYP51. | Biochimica et biophysica acta 20050101 |
| Exploring hepatic hormone actions using a compilation of gene expression profiles. | BMC physiology 20050101 |
| Genome-wide structural and evolutionary analysis of the P450 monooxygenase genes (P450ome) in the white rot fungus Phanerochaete chrysosporium: evidence for gene duplications and extensive gene clustering. | BMC genomics 20050101 |
| Vesicle fluctuation analysis of the effects of sterols on membrane bending rigidity. | European biophysics journal : EBJ 20041201 |
| Meiosis-activating sterol synthesis in rat preovulatory follicle: is it involved in resumption of meiosis? | Biology of reproduction 20041201 |
| Lead nitrate-induced development of hypercholesterolemia in rats: sterol-independent gene regulation of hepatic enzymes responsible for cholesterol homeostasis. | Toxicology letters 20041201 |
| Lanostanoid triterpenes from Laetiporus sulphureus and apoptosis induction on HL-60 human myeloid leukemia cells. | Journal of natural products 20041201 |
| Bioactive friedolanostanes and 11(10-->8)-abeolanostanes from the bark of Garcinia speciosa. | Journal of natural products 20041201 |
| 27-norlanostane glycosides from the bulbs of Muscari paradoxum. | Journal of natural products 20041201 |
| Studies on the expression levels of sterol-metabolizing enzymes in the obese model SHR/NDmcr-cp rats. | Clinical and experimental pharmacology & physiology 20041201 |
| Biochemical characterization of terbinafine-resistant Trichophyton rubrum isolates. | Medical mycology 20041201 |
| Molecular mechanisms of vitamin E transport. | Annals of the New York Academy of Sciences 20041201 |
| Cloning and characterization of the lanosterol 14alpha-demethylase (ERG11) gene in Cryptococcus neoformans. | Biochemical and biophysical research communications 20041112 |
| Insight into steroid scaffold formation from the structure of human oxidosqualene cyclase. | Nature 20041104 |
| Agrobacterium tumefaciens-mediated transformation of the antitumor clavaric acid-producing basidiomycete Hypholoma sublateritium. | Current genetics 20041101 |
| New lanostane-type triterpenes from Fomes officinalis. | Chemical & pharmaceutical bulletin 20041101 |
| Anti-inflammatory and anti-hyaluronate lyase activities of lanostanoids from Piptoporus betulinus. | The Journal of antibiotics 20041101 |
| What's so special about cholesterol? | Lipids 20041101 |
| Cholesterol is essential for mitosis progression and its deficiency induces polyploid cell formation. | Experimental cell research 20041015 |
| Geranylgeraniol regulates negatively caspase-1 autoprocessing: implication in the Th1 response against Mycobacterium tuberculosis. | Journal of immunology (Baltimore, Md. : 1950) 20041015 |
| Oxysteroids: a new class of steroids with autocrine and paracrine functions. | Trends in endocrinology and metabolism: TEM 20041001 |
| Abnormal steroidogenesis in three patients with Antley-Bixler syndrome: apparent decreased activity of 17alpha-hydroxylase, 17,20-lyase and 21-hydroxylase. | Pediatrics international : official journal of the Japan Pediatric Society 20041001 |
| Low concentrations of the non-ionic detergent Nonidet P-40 interfere with sterol biogenesis and viability of the yeast Saccharomyces cerevisiae. | FEMS microbiology letters 20040901 |
| A low-toxicity method for the separation of lanosterol and dihydrolanosterol from commercial mixtures. | Steroids 20040901 |
| CYP51 from Trypanosoma brucei is obtusifoliol-specific. | Biochemistry 20040824 |
| Undetectable maternal serum uE3 and postnatal abnormal sterol and steroid metabolism in Antley-Bixler syndrome. | American journal of medical genetics. Part A 20040815 |
| Genome-wide expression profiling reveals genes associated with amphotericin B and fluconazole resistance in experimentally induced antifungal resistant isolates of Candida albicans. | The Journal of antimicrobial chemotherapy 20040801 |
| Homology modeling of lanosterol 14alpha-demethylase of Candida albicans and Aspergillus fumigatus and insights into the enzyme-substrate Interactions. | Journal of biomolecular structure & dynamics 20040801 |
| Compound heterozygous mutations of cytochrome P450 oxidoreductase gene (POR) in two patients with Antley-Bixler syndrome. | American journal of medical genetics. Part A 20040801 |
| Quantitation of lanosterol and its major metabolite FF-MAS in an inhibition assay of CYP51 by azoles with atmospheric pressure photoionization based LC-MS/MS. | Journal of the American Society for Mass Spectrometry 20040801 |
| Sterol metabolism in the opportunistic pathogen Pneumocystis: advances and new insights. | Lipids 20040801 |
| New lanostane-type triterpenoids from Ganoderma applanatum. | Journal of natural products 20040701 |
| New aspects on lanosterol 14alpha-demethylase and cytochrome P450 evolution: lanosterol/cycloartenol diversification and lateral transfer. | Journal of molecular evolution 20040701 |
| Selective anti-Toxoplasma gondii activities of azasterols. | International journal of antimicrobial agents 20040601 |
| Phytoestrogen cimicifugoside-mediated inhibition of catecholamine secretion by blocking nicotinic acetylcholine receptor in bovine adrenal chromaffin cells. | The Journal of pharmacology and experimental therapeutics 20040501 |
| The role of cholesterol in the activity of pneumolysin, a bacterial protein toxin. | Biophysical journal 20040501 |
| Ananosic acids B and C, two new 18(13-->12)-abeo-lanostane triterpenoids from Kadsura ananosma. | Journal of natural products 20040501 |
| Eucosterol-type nortriterpenoids from Merwilla natalensis. | Journal of natural products 20040501 |
| Roles of gonadotropins and meiosis-activating sterols in meiotic resumption of cultured follicle-enclosed mouse oocytes. | Molecular and cellular endocrinology 20040415 |
| Efficient routes to epimerically-pure side-chain derivatives of lanosterol. | Steroids 20040401 |
| Enzymatic cyclization of 22,23-dihydro-2,3-oxidosqualene into euph-7-en-3beta-ol and bacchar-12-en-3beta-ol by recombinant beta-amyrin synthase. | Journal of the American Chemical Society 20040324 |
| The monotopic membrane protein human oxidosqualene cyclase is active as monomer. | Biochemical and biophysical research communications 20040305 |
| A functional cytochrome P450 lanosterol 14 alpha-demethylase CYP51 enzyme in the acrosome: transport through the Golgi and synthesis of meiosis-activating sterols. | Endocrinology 20040301 |
| Two new cyclolanostanol glycosides from the aerial parts of Cimicifuga foetida. | Journal of Asian natural products research 20040301 |
| Characterization of a human Sec14-like protein cDNA SEC14L3 highly homologous to human SPF/TAP. | Molecular biology reports 20040301 |
| Impact of 10 dietary sterols on growth and reproduction of Daphnia galeata. | Journal of chemical ecology 20040301 |
| CYP51--the omnipotent P450. | Molecular and cellular endocrinology 20040227 |
| Lanosterol and cholesterol-induced variations in bilayer elasticity probed by 2H NMR relaxation. | Langmuir : the ACS journal of surfaces and colloids 20040217 |
| Cholesterol-lowering properties of Ganoderma lucidum in vitro, ex vivo, and in hamsters and minipigs. | Lipids in health and disease 20040101 |
| Modeling lipid-sterol bilayers: applications to structural evolution, lateral diffusion, and rafts. | Methods in enzymology 20040101 |
| Fungal biofilms and drug resistance. | Emerging infectious diseases 20040101 |
| Cloning and analysis of Trypanosoma cruzi lanosterol 14alpha-demethylase. | Molecular and biochemical parasitology 20031201 |
| Novel sterols synthesized via the CYP27A1 metabolic pathway. | Archives of biochemistry and biophysics 20031201 |
| Lanosterol and tetranorlanosterol glycosides from the bulbs of Muscari paradoxum. | Phytochemistry 20031201 |
| Changes in cholesterol and its precursors during the first days after major trauma. | Wiener klinische Wochenschrift 20031128 |
| Combined overexpression of genes of the ergosterol biosynthetic pathway leads to accumulation of sterols in Saccharomyces cerevisiae. | FEMS yeast research 20031001 |
| Localization of mammalian NAD(P)H steroid dehydrogenase-like protein on lipid droplets. | The Journal of biological chemistry 20030919 |
| Conservation in the CYP51 family. Role of the B' helix/BC loop and helices F and G in enzymatic function. | Biochemistry 20030805 |
| Characterization of a lanosterol 14 alpha-demethylase from Pneumocystis carinii. | American journal of respiratory cell and molecular biology 20030801 |
| Anti-inflammatory lanostane-type triterpene acids from Piptoporus betulinus. | Journal of natural products 20030801 |
| In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activity. | Biochimica et biophysica acta 20030704 |
| Revision and confirmation of the regiochemistry of isoxazoles derived from methyl oleanonate and lanost-8-en-3-one. Synthesis of a new lanostane triterpenoid with a cyano-enone functionality in ring A. | The Journal of organic chemistry 20030613 |
| Lanosterol metabolism and sterol regulatory element binding protein (SREBP) expression in male germ cell maturation. | The Journal of steroid biochemistry and molecular biology 20030601 |
| Phylogeny of choanozoa, apusozoa, and other protozoa and early eukaryote megaevolution. | Journal of molecular evolution 20030501 |
| Mechanistic insights into oxidosqualene cyclizations through homology modeling. | Journal of computational chemistry 20030430 |
| Production of progesterone from de novo-synthesized cholesterol in cumulus cells and its physiological role during meiotic resumption of porcine oocytes. | Biology of reproduction 20030401 |
| Saccharomyces cerevisiae Dap1p, a novel DNA damage response protein related to the mammalian membrane-associated progesterone receptor. | Eukaryotic cell 20030401 |
| Antitumor agents 220. Antitumor-promoting effects of cimigenol and related compounds on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis. | Bioorganic & medicinal chemistry 20030320 |
| Human serum paraoxonase 1 decreases macrophage cholesterol biosynthesis: possible role for its phospholipase-A2-like activity and lysophosphatidylcholine formation. | Arteriosclerosis, thrombosis, and vascular biology 20030301 |
| Drug induced proteome changes in Candida albicans: comparison of the effect of beta(1,3) glucan synthase inhibitors and two triazoles, fluconazole and itraconazole. | Proteomics 20030301 |
| [Studies on the new triterpenoid saponin of the aerial part of Cimicifuga foetida]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030301 |
| Structure-based de novo design, synthesis, and biological evaluation of non-azole inhibitors specific for lanosterol 14alpha-demethylase of fungi. | Journal of medicinal chemistry 20030213 |
| Conservation and cloning of CYP51: a sterol 14 alpha-demethylase from Mycobacterium smegmatis. | Biochemical and biophysical research communications 20030207 |
| Identification of farnesoid X receptor beta as a novel mammalian nuclear receptor sensing lanosterol. | Molecular and cellular biology 20030201 |
| Triterpenoids from the orchids Agrostophyllum brevipes and Agrostophyllum callosum. | Phytochemistry 20030201 |
| [Serum markers in relation to cognitive functioning in an aging population: results of the Maastricht Aging Study (MAAS)]. | Tijdschrift voor gerontologie en geriatrie 20030201 |
| [Studies on new trierpenoid constituents from the Rhizoma of Cimicifuga foetida]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20030201 |
| Formation of the C ring in the lanosterol biosynthesis from squalene. | Organic letters 20030123 |
| Many facets of mammalian lanosterol 14alpha-demethylase from the evolutionarily conserved cytochrome P450 family CYP51. | Archives of biochemistry and biophysics 20030101 |
| Serum cholesterol, precursors and metabolites and cognitive performance in an aging population. | Neurobiology of aging 20030101 |
| Supernatant protein factor and tocopherol-associated protein: an unexpected link between cholesterol synthesis and vitamin E (review). | The Journal of nutritional biochemistry 20030101 |
| Protein prenyltransferases. | Genome biology 20030101 |
| Two new 24-isopropenyl-lanostanoids from Tillandsia brachycaulos. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101 |
| Scale-up of a liquid static culture process for hyperproduction of ganoderic acid by the medicinal mushroom Ganoderma lucidum. | Biotechnology progress 20030101 |
| Identification of two proteins induced by exposure of the pathogenic fungus Candida glabrata to fluconazole. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021225 |
| Creating new supramolecular materials by architecture of three-dimensional nanocrystal fiber networks. | Journal of the American Chemical Society 20021218 |
| Desmosterolosis presenting with multiple congenital anomalies and profound developmental delay. | American journal of medical genetics 20021215 |
| Directed evolution experiments reveal mutations at cycloartenol synthase residue His477 that dramatically alter catalysis. | Organic letters 20021212 |
| A novel sterol 14alpha-demethylase/ferredoxin fusion protein (MCCYP51FX) from Methylococcus capsulatus represents a new class of the cytochrome P450 superfamily. | The Journal of biological chemistry 20021206 |
| Nuclear receptor agonists stimulate release of arachidonic acid from rat liver cells. | Prostaglandins, leukotrienes, and essential fatty acids 20021201 |
| Sterol biosynthesis in Pneumocystis: unique steps that define unique targets. | Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 20021201 |
| Novel hydroquinone as a matrix metallo-proteinase inhibitor from the mushroom, Piptoporus betulinus. | Bioscience, biotechnology, and biochemistry 20021201 |
| The role of cytochrome P450 in the regulation of cholesterol biosynthesis. | Lipids 20021201 |
| Evidence for multiple sterol methyl transferase pathways in Pneumocystis carinii. | Lipids 20021201 |
| Progesterone and 17 alpha-OH-progesterone in concentrations similar to that of preovulatory follicular fluid is without effect on resumption of meiosis in mouse cumulus enclosed oocytes cultured in the presence of hypoxanthine. | Steroids 20021101 |
| Triterpenoid constituents isolated from the bark of Abies sachalinensis. | Journal of natural products 20021101 |
| Anisotropic motion and molecular dynamics of cholesterol, lanosterol, and ergosterol in lecithin bilayers studied by quasi-elastic neutron scattering. | Biochemistry 20021029 |
| Complete characterisation of lanolin steryl esters by sub-ambient pressure gas chromatography-mass spectrometry in the electron impact and chemical ionisation modes. | Journal of chromatography. A 20020913 |
| Concomitant C-ring Expansion and D-ring formation in lanosterol biosynthesis from squalene without violation of Markovnikov's rule. | Journal of the American Chemical Society 20020904 |
| A cAMP-responsive element binding site is essential for sterol regulation of the human lanosterol 14alpha-demethylase gene (CYP51). | Molecular endocrinology (Baltimore, Md.) 20020801 |
| Conversion of a plant oxidosqualene-cycloartenol synthase to an oxidosqualene-lanosterol cyclase by random mutagenesis. | Biochemistry 20020702 |
| Cholesterol metabolism in normal and heterozygous familial hypercholesterolemic newborns. | The Journal of laboratory and clinical medicine 20020701 |
| Profile of cholesterol-related sterols in aged amyloid precursor protein transgenic mouse brain. | Journal of lipid research 20020701 |
| Comprehensive and definitive structural identities of Pneumocystis carinii sterols. | Journal of lipid research 20020701 |
| Altered gene expression of hepatic lanosterol 14alpha-demethylase (CYP51) in lead nitrate-treated rats. | Archives of toxicology 20020701 |
| Abnormal sterol metabolism in a patient with Antley-Bixler syndrome and ambiguous genitalia. | American journal of medical genetics 20020615 |
| Sterol 14alpha-demethylase activity in Streptomyces coelicolor A3(2) is associated with an unusual member of the CYP51 gene family. | The Biochemical journal 20020601 |
| The Salmonella-containing vacuole is a major site of intracellular cholesterol accumulation and recruits the GPI-anchored protein CD55. | Cellular microbiology 20020601 |
| Polyene substrates with unusual methylation patterns to probe the active sites of three catalytic antibodies. | Bioorganic & medicinal chemistry 20020501 |
| The Pneumocystis carinii drug target S-adenosyl-L-methionine:sterol C-24 methyl transferase has a unique substrate preference. | Molecular microbiology 20020501 |
| Membrane-bound enzymes of cholesterol synthesis from lanosterol. | Biochemical and biophysical research communications 20020419 |
| My years with Konrad, a memoir. | Biochemical and biophysical research communications 20020419 |
| Directed evolution to generate cycloartenol synthase mutants that produce lanosterol. | Organic letters 20020418 |
| Inhibition of tumor-promoting effects by poricoic acids G and H and other lanostane-type triterpenes and cytotoxic activity of poricoic acids A and G from Poria cocos. | Journal of natural products 20020401 |
| New lanostanoids, elfvingic acids A-H, from the fruit body of Elfvingia applanata. | Journal of natural products 20020401 |
| Modeling of binding modes and inhibition mechanism of some natural ligands of farnesyl transferase using molecular docking. | Journal of medicinal chemistry 20020328 |
| Elution behavior of unsaponifiable lipids with various capillary electrochromatographic stationary phases. | Journal of chromatography. A 20020308 |
| From lanosterol to cholesterol: structural evolution and differential effects on lipid bilayers. | Biophysical journal 20020301 |
| Differential effects of ergosterol and cholesterol on Cdk1 activation and SRE-driven transcription. | European journal of biochemistry 20020301 |
| New lanostanoids from the fungus Ganoderma concinna. | Journal of natural products 20020301 |
| Mechanism of azole antifungal activity as determined by liquid chromatographic/mass spectrometric monitoring of ergosterol biosynthesis. | Journal of mass spectrometry : JMS 20020301 |
| Lanosterol 14alpha-demethylase and MAS sterols in mammalian gametogenesis. | Molecular and cellular endocrinology 20020222 |
| Role of meiosis activating sterols, MAS, in induced oocyte maturation. | Molecular and cellular endocrinology 20020222 |
| Molecular basis of resistance to azole antifungals. | Trends in molecular medicine 20020201 |
| Yeast oxidosqualene cyclase (Erg7p) is a major component of lipid particles. | The Journal of biological chemistry 20020125 |
| Cloning and expression of sterol Delta 14-reductase from bovine liver. | European journal of biochemistry 20020101 |
| New lanostanoids from the mushroom Ganoderma lucidum. | Journal of natural products 20020101 |
| Lanostanoids of Amentotaxus formosana. | Journal of natural products 20020101 |
| Two-stage culture process for improved production of ganoderic acid by liquid fermentation of higher fungus Ganoderma lucidum. | Biotechnology progress 20020101 |
| Is Pneumocystis a plant? | The Journal of eukaryotic microbiology 20020101 |
| Chemopreventive effect of farnesol and lanosterol on colon carcinogenesis. | Cancer detection and prevention 20020101 |
| Substrate recognition sites in 14alpha-sterol demethylase from comparative analysis of amino acid sequences and X-ray structure of Mycobacterium tuberculosis CYP51. | Journal of inorganic biochemistry 20011215 |
| Gonadotropin-induced accumulation of 4,4-dimethylsterols in mouse ovaries and its temporal relation to meiosis. | Biology of reproduction 20011201 |
| Anticomplement activity of terpenoids from the spores of Ganoderma lucidum. | Planta medica 20011201 |
| Regulation of hepatic lanosterol 14 alpha-demethylase gene expression by dietary cholesterol and cholesterol-lowering agents. | Archives of biochemistry and biophysics 20011115 |
| Steryl and stanyl esters of fatty acids by solvent-free esterification and transesterification in vacuo using lipases from Rhizomucor miehei, Candida antarctica, and Carica papaya. | Journal of agricultural and food chemistry 20011101 |
| Blocking protein geranylgeranylation is essential for lovastatin-induced apoptosis of human acute myeloid leukemia cells. | Leukemia 20010901 |
| New pentanorlanostane derivatives, cladosporide B-D, as characteristic antifungal agents against Aspergillus fumigatus, isolated from Cladosporium sp. | The Journal of antibiotics 20010901 |
| Identification of a novel mutation in 3beta-hydroxysteroid-Delta8-Delta7-isomerase in a case of Conradi-Hünermann-Happle syndrome. | Experimental dermatology 20010801 |
| [A new triterpene from the fruiting bodies of Ganoderma lucidum]. | Yao xue xue bao = Acta pharmaceutica Sinica 20010801 |
| Obtusifoliol 14alpha-demethylase (CYP51) antisense Arabidopsis shows slow growth and long life. | Biochemical and biophysical research communications 20010706 |
| The interactions of amphotericin B with various sterols in relation to its possible use in anticancer therapy. | Biophysical chemistry 20010702 |
| Neutral sterols of rat epididymis. High concentrations of dehydrocholesterols in rat caput epididymidis. | Journal of lipid research 20010701 |
| Content of meiosis activating sterols in equine follicular fluids: correlation to follicular size and dominance. | Theriogenology 20010701 |
| Trypanosome and animal lanosterol synthases use different catalytic motifs. | Organic letters 20010614 |
| Mammalian exocrine secretions XVI. Constitutents of secretion of supplementary sacculi of dwarf hamster, Phodopus sungorus sungorus. | Journal of chemical ecology 20010601 |
| Cholesterol biosynthesis from lanosterol. A concerted role for Sp1 and NF-Y-binding sites for sterol-mediated regulation of rat 7-dehydrocholesterol reductase gene expression. | The Journal of biological chemistry 20010525 |
| Molecular dynamics simulation of the structure of dimyristoylphosphatidylcholine bilayers with cholesterol, ergosterol, and lanosterol. | Biophysical journal 20010401 |
| Anaerobiosis induces complex changes in sterol esterification pattern in the yeast Saccharomyces cerevisiae. | FEMS microbiology letters 20010401 |
| Ergosterol biosynthesis in novel melanized fungi from hypersaline environments. | Journal of lipid research 20010301 |
| [Studies on quality specification standards for Saposhnicovia divaricata (Turcz.) Schischk]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20010301 |
| LDL downregulates CYP51 in porcine vascular endothelial cells and in the arterial wall through a sterol regulatory element binding protein-2-dependent mechanism. | Circulation research 20010216 |
| Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions. | The Biochemical journal 20010201 |
| Meiosis-activating sterol and the maturation of isolated mouse oocytes. | Biology of reproduction 20010101 |
| Role of meiosis-activating sterols in rat oocyte maturation: effects of specific inhibitors and changes in the expression of lanosterol 14alpha-demethylase during the preovulatory period. | Biology of reproduction 20010101 |
| Quantification of plasma membrane ergosterol of Saccharomyces cerevisiae by direct-injection atmospheric pressure chemical ionization/tandem mass spectrometry. | Analytical biochemistry 20010101 |
| Molecular cloning and expression in yeast of 2,3-oxidosqualene-triterpenoid cyclases from Arabidopsis thaliana. | Plant molecular biology 20010101 |
| Localisation of lanosterol 14alpha-demethylase in round and elongated spermatids of the mouse testis: an immunoelectron microscopic and stereological study. | Pflugers Archiv : European journal of physiology 20010101 |
| Inhibitors of sterol biosynthesis and amphotericin B reduce the viability of pneumocystis carinii f. sp. carinii. | Antimicrobial agents and chemotherapy 20000601 |
| Synthesis of 25-aminosterols, new antifungal agents. | Bioorganic & medicinal chemistry letters 19990607 |
| Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo. | Biochemistry 19940419 |
| Plant sterol biosynthesis: 7-oxo-obtusifoliol analogues as potential selective inhibitors of cytochrome P-450 dependent obtusifoliol 14 alpha-demethylase. | Biochimica et biophysica acta 19920423 |
| Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase. | Journal of medicinal chemistry 19920101 |
| Effects of environmentally encountered epoxides on mouse liver epoxide-metabolizing enzymes. | Biochemical pharmacology 19910601 |
| [Steroid alkaloids. 138(12). Chemical composition of the fruits and grains of Holarrhena mitis R. Br. (Apocynacea): alkaloids and unsaponifiable material]. | Annales pharmaceutiques francaises 19721201 |
| 3',5'-cyclic adenosine monophosphate response element binding protein up-regulated cytochrome P450 lanosterol 14alpha-demethylase expression involved in follicle-stimulating hormone-induced mouse oocyte maturation. | Molecular endocrinology (Baltimore, Md.) |