Home Other Building Blocks Kinetin riboside

Kinetin riboside

CAS No.:
4338-47-0
Catalog Number:
AG00352P
Molecular Formula:
C15H17N5O5
Molecular Weight:
347.3260
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
99%
1 week
United States
$173
- +
Product Description
Catalog Number:
AG00352P
Chemical Name:
Kinetin riboside
CAS Number:
4338-47-0
Molecular Formula:
C15H17N5O5
Molecular Weight:
347.3260
MDL Number:
MFCD00037987
IUPAC Name:
(2R,3R,4S,5R)-2-[6-(furan-2-ylmethylamino)purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
InChI:
InChI=1S/C15H17N5O5/c21-5-9-11(22)12(23)15(25-9)20-7-19-10-13(17-6-18-14(10)20)16-4-8-2-1-3-24-8/h1-3,6-7,9,11-12,15,21-23H,4-5H2,(H,16,17,18)/t9-,11-,12-,15-/m1/s1
InChI Key:
CAGLGYNQQSIUGX-SDBHATRESA-N
SMILES:
OC[C@H]1O[C@H]([C@@H]([C@@H]1O)O)n1cnc2c1ncnc2NCc1ccco1
EC Number:
224-389-3
Properties
Complexity:
460  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
347.123g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
347.331g/mol
Monoisotopic Mass:
347.123g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
139A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.2  
Literature
Title Journal
A small molecule screening strategy with validation on human leukemia stem cells uncovers the therapeutic efficacy of kinetin riboside. Blood 20120202
Antiproliferative activity of kinetin riboside on HCT-15 colon cancer cell line. Nucleosides, nucleotides & nucleic acids 20120101
Simultaneous determination of different endogenetic plant growth regulators in common green seaweeds using dispersive liquid-liquid microextraction method. Plant physiology and biochemistry : PPB 20111101
Effects of kinetin riboside on proliferation and proapoptotic activities in human normal and cancer cell lines. Journal of cellular biochemistry 20110801
Anticancer activity of natural cytokinins: a structure-activity relationship study. Phytochemistry 20100801
FKBP38 protects Bcl-2 from caspase-dependent degradation. The Journal of biological chemistry 20100326
The experimental chemotherapeutic N6-furfuryladenosine (kinetin-riboside) induces rapid ATP depletion, genotoxic stress, and CDKN1A(p21) upregulation in human cancer cell lines. Biochemical pharmacology 20090401
Inhibitory effect of kinetin riboside in human heptamoa, HepG2. Molecular bioSystems 20090101
Ribose-modified purine nucleosides as ribonucleotide reductase inhibitors. Synthesis, antitumor activity, and molecular modeling of N6-substituted 3'-C-methyladenosine derivatives. Journal of medicinal chemistry 20080724
Constrained NBMPR analogue synthesis, pharmacophore mapping and 3D-QSAR modeling of equilibrative nucleoside transporter 1 (ENT1) inhibitory activity. Bioorganic & medicinal chemistry 20080401
Kinetin riboside preferentially induces apoptosis by modulating Bcl-2 family proteins and caspase-3 in cancer cells. Cancer letters 20080308
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Properties