Characterisation of acetylcholinesterase release from neuronal cells.

Chemico-biological interactions 20130325

Proteolysis controls endogenous substance P levels.

PloS one 20130101

Extra- and intracellular imaging of human matrix metalloprotease 11 (hMMP-11) with a cell-penetrating FRET substrate.

The Journal of biological chemistry 20121102

Integrin β8 signaling in neonatal hypoxic-ischemic brain injury.

Neurotoxicity research 20121101

Downregulation of matrix metalloproteinase-9 mRNA by valproic acid plays a role in inhibiting the shedding of MHC class I-related molecules A and B on the surface of human osteosarcoma cells.

Oncology reports 20121101

Suppression of tunicamycin-induced CD44v6 ectodomain shedding and apoptosis is correlated with temporal expression patterns of active ADAM10, MMP-9 and MMP-13 proteins in Caki-2 renal carcinoma cells.

Oncology reports 20121101

Changes in mitochondrial DNA alter expression of nuclear encoded genes associated with tumorigenesis.

Experimental cell research 20121015

Autocrine effect of EGFR ligands on the pro-inflammatory response induced by PM(2.5) exposure in human bronchial epithelial cells.

Archives of toxicology 20121001

Novel sonomicrometry of ex vivo diaphragm after phrenic nerve injury: Role of matrix metalloproteinases.

Synapse (New York, N.Y.) 20120801

Activated human hydroxy-carboxylic acid receptor-3 signals to MAP kinase cascades via the PLC-dependent PKC and MMP-mediated EGFR pathways.

British journal of pharmacology 20120701

Increased expression of matrix metalloproteinases mediates thromboxane A2-induced invasion in lung cancer cells.

Current cancer drug targets 20120701

Aβ₁₋₄₂-RAGE interaction disrupts tight junctions of the blood-brain barrier via Ca²⁺-calcineurin signaling.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20120627

Metalloproteinases regulate CD40L shedding from platelets and pulmonary recruitment of neutrophils in abdominal sepsis.

Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20120601

Effects of MMP inhibitors incorporated within dental adhesives.

Journal of dental research 20120601

Involvement of matrix metalloproteinase-9 in the development of morphine tolerance.

European journal of pharmacology 20120515

Crosstalk between oligodendrocytes and cerebral endothelium contributes to vascular remodeling after white matter injury.

Glia 20120501

Microvesicles shed by oligodendroglioma cells and rheumatoid synovial fibroblasts contain aggrecanase activity.

Matrix biology : journal of the International Society for Matrix Biology 20120501

Porphyromonas gingivalis promotes monocyte migration by activating MMP-9.

Journal of periodontal research 20120401

A dynamic model of calcific nodule destabilization in response to monocyte- and oxidized lipid-induced matrix metalloproteinases.

American journal of physiology. Cell physiology 20120215

A pharmacologically-based array to identify targets of cyclosporine A-induced toxicity in cultured renal proximal tubule cells.

Toxicology and applied pharmacology 20120115

Spinal matrix metalloproteinase 3 mediates inflammatory hyperalgesia via a tumor necrosis factor-dependent mechanism.

Neuroscience 20120103

Permissive effect of EGFR-activated pathways on RVI and their anti-apoptotic effect in hypertonicity-exposed mIMCD3 cells.

Bioscience reports 20111201

The anti-invasive activity of synthetic alkaloid ethoxyfagaronine on L1210 leukemia cells is mediated by down-regulation of plasminogen activators and MT1-MMP expression and activity.

Investigational new drugs 20111001

Doxycycline could aggravate the absence-like epileptic seizures of WAG/Rij rats via matrix metalloproteinase inhibition.

Neurochemistry international 20111001

ADAM-17/tumor necrosis factor-α-converting enzyme inhibits neurogenesis and promotes gliogenesis from neural stem cells.

Stem cells (Dayton, Ohio) 20111001

Zinc-triggered induction of tissue plasminogen activator by brain-derived neurotrophic factor and metalloproteinases.

Journal of neurochemistry 20110901

Inhibition of MMPs by alcohols.

Dental materials : official publication of the Academy of Dental Materials 20110901

Non-coding nucleotides and amino acids near the active site regulate peptide deformylase expression and inhibitor susceptibility in Chlamydia trachomatis.

Microbiology (Reading, England) 20110901

Interleukin-lβ induces migration of rat arterial smooth muscle cells through a mechanism involving increased matrix metalloproteinase-2 activity.

The Journal of surgical research 20110801

Methamphetamine-associated cleavage of the synaptic adhesion molecule intercellular adhesion molecule-5.

Journal of neurochemistry 20110801

Design, synthesis, docking, and biological evaluation of novel diazide-containing isoxazole- and pyrazole-based histone deacetylase probes.

Journal of medicinal chemistry 20110714

Advancing the treatment of conjunctival scarring: a novel ex vivo model.

Archives of ophthalmology (Chicago, Ill. : 1960) 20110501

Fluoride does not inhibit enamel protease activity.

Journal of dental research 20110401

LIM kinase1 modulates function of membrane type matrix metalloproteinase 1: implication in invasion of prostate cancer cells.

Molecular cancer 20110101

Calpain activator dibucaine induces platelet apoptosis.

International journal of molecular sciences 20110101

Matrix metalloproteinase-2 and -9 secreted by leukemic cells increase the permeability of blood-brain barrier by disrupting tight junction proteins.

PloS one 20110101

Soluble amyloid precursor protein: a novel proliferation factor of adult progenitor cells of ectodermal and mesodermal origin.

Stem cell research & therapy 20110101

Inhibition of matrix metalloproteinases in Siberian hamsters impedes photostimulated recrudescence of ovaries.

Reproduction (Cambridge, England) 20101201

Increased Na, K-ATPase alpha2 isoform gene expression by ammonia in astrocytes and in brain in vivo.

Neurochemistry international 20101101

Serotonin increases ERK1/2 phosphorylation in astrocytes by stimulation of 5-HT2B and 5-HT2C receptors.

Neurochemistry international 20101101

Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Bioorganic & medicinal chemistry letters 20101101

Stromal remodelling is required for progressive involution of the rat ventral prostate after castration: identification of a matrix metalloproteinase-dependent apoptotic wave.

International journal of andrology 20101001

Ovarian steroids, mitogen-activated protein kinases, and/or aspartic proteinases cooperate to control endometrial remodeling by regulating gene expression in the stroma and glands.

Endocrinology 20100901

Cocarcinogenic effect of capsaicin involves activation of EGFR signaling but not TRPV1.

Cancer research 20100901

Matrix metalloproteinase-9 is upregulated in nucleophosmin-anaplastic lymphoma kinase-positive anaplastic lymphomas and activated at the cell surface by the chaperone heat shock protein 90 to promote cell invasion.

Cancer research 20100901

Regulation of the blood-brain barrier integrity by pericytes via matrix metalloproteinases mediated activation of vascular endothelial growth factor in vitro.

Brain research 20100806

Enhanced matrix metalloproteinase activity in the spontaneously hypertensive rat: VEGFR-2 cleavage, endothelial apoptosis, and capillary rarefaction.

Journal of vascular research 20100801

Thymoquinone-induced Neu4 sialidase activates NFκB in macrophage cells and pro-inflammatory cytokines in vivo.

Glycoconjugate journal 20100801

Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells.

FEBS letters 20100702

Thromboxane prostanoid receptor stimulation induces shedding of the transmembrane chemokine CX3CL1 yet enhances CX3CL1-dependent leukocyte adhesion.

American journal of physiology. Cell physiology 20100601

Use of a specific MMP-inhibitor (galardin) for preservation of hybrid layer.

Dental materials : official publication of the Academy of Dental Materials 20100601

Induction of CD44 cleavage in articular chondrocytes.

Arthritis and rheumatism 20100501

Neoplastic progression of the human breast cancer cell line G3S1 is associated with elevation of cytoskeletal dynamics and upregulation of MT1-MMP.

International journal of oncology 20100401

Matrix metalloproteinase inhibition enhances the rate of nerve regeneration in vivo by promoting dedifferentiation and mitosis of supporting schwann cells.

Journal of neuropathology and experimental neurology 20100401

The role of calpain in the regulation of ADAM17-dependent GPIbalpha ectodomain shedding.

Archives of biochemistry and biophysics 20100315

Cholesterol efflux stimulates metalloproteinase-mediated cleavage of occludin and release of extracellular membrane particles containing its C-terminal fragments.

Experimental cell research 20100201

ATP induced microglial cell migration through non-transcriptional activation of matrix metalloproteinase-9.

Archives of pharmacal research 20100201

Potent homocysteine-induced ERK phosphorylation in cultured neurons depends on self-sensitization via system Xc(-).

Toxicology and applied pharmacology 20100115

Three-dimensional cell culture array using magnetic force-based cell patterning for analysis of invasive capacity of BALB/3T3/v-src.

Lab on a chip 20091207

ERK phosphorylation in intact, adult brain by alpha(2)-adrenergic transactivation of EGF receptors.

Neurochemistry international 20091201

Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production.

American journal of respiratory and critical care medicine 20091101

Chronic treatment of astrocytes with therapeutically relevant fluoxetine concentrations enhances cPLA2 expression secondary to 5-HT2B-induced, transactivation-mediated ERK1/2 phosphorylation.

Psychopharmacology 20091101

Analysis of gene expression in PTHrP-/- mammary buds supports a role for BMP signaling and MMP2 in the initiation of ductal morphogenesis.

Developmental dynamics : an official publication of the American Association of Anatomists 20091101

Altered expression of glycoproteins on the cell surface of Jurkat cells during etoposide-induced apoptosis: shedding and intracellular translocation of glycoproteins.

Biochimica et biophysica acta 20091001

Grassystatins A-C from marine cyanobacteria, potent cathepsin E inhibitors that reduce antigen presentation.

Journal of medicinal chemistry 20090924

Evaluation of protease inhibitors and an antioxidant for treatment of sulfur mustard-induced toxic lung injury.

Toxicology 20090901

In vitro and ex vivo activity of peptide deformylase inhibitors against Mycobacterium tuberculosis H37Rv.

International journal of antimicrobial agents 20090901

A protease inhibitor discovery method using fluorescence correlation spectroscopy with position-specific labeled protein substrates.

Analytical biochemistry 20090715

Transmural pressure and axial loading interactively regulate arterial remodeling ex vivo.

American journal of physiology. Heart and circulatory physiology 20090701

Inhibition of matrix metalloproteinases enhances in vitro repair of the meniscus.

Clinical orthopaedics and related research 20090601

Matrix metalloproteinase inhibition reduces oxidative stress associated with cerebral amyloid angiopathy in vivo in transgenic mice.

Journal of neurochemistry 20090601

Prolonged inhibition of protein kinase A results in metalloproteinase-dependent platelet GPIbalpha shedding.

Thrombosis research 20090501

Secreted cysteine-rich FGF receptor derives from posttranslational processing by furin-like prohormone convertases.

Biochemical and biophysical research communications 20090501

Cell migration in response to the amino-terminal fragment of urokinase requires epidermal growth factor receptor activation through an ADAM-mediated mechanism.

Journal of vascular surgery 20090501

Nonlinear optical microscopy reveals invading endothelial cells anisotropically alter three-dimensional collagen matrices.

Experimental cell research 20090201

Activated human neutrophils rapidly release the chemotactically active D2D3 form of the urokinase-type plasminogen activator receptor (uPAR/CD87).

Molecular and cellular biochemistry 20090101

Cutting edge: the metalloproteinase ADAM17/TNF-alpha-converting enzyme regulates proteolytic shedding of the MHC class I-related chain B protein.

Journal of immunology (Baltimore, Md. : 1950) 20090101

Expression profiles of matrix metalloproteinase 9 in teleost fish provide evidence for its active role in initiation and resolution of inflammation.

Immunology 20081201

Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation.

Psychopharmacology 20081201

Metalloproteinase- and gamma-secretase-mediated cleavage of protein-tyrosine phosphatase receptor type Z.

The Journal of biological chemistry 20081107

Protective effect of ilomastat on trinitrobenzenesulfonic acid-induced ulcerative colitis in rats.

World journal of gastroenterology 20081007

Matrix metalloproteinase 2 improves the transplanted adipocyte survival in mice.

European journal of clinical investigation 20081001

Beta-blockers alprenolol and carvedilol stimulate beta-arrestin-mediated EGFR transactivation.

Proceedings of the National Academy of Sciences of the United States of America 20080923

Introduction of the 4-(4-bromophenyl)benzenesulfonyl group to hydrazide analogs of Ilomastat leads to potent gelatinase B (MMP-9) inhibitors with improved selectivity.

Bioorganic & medicinal chemistry 20080915

Gamma-secretase and metalloproteinase activity regulate the distribution of endoplasmic reticulum to hippocampal neuron dendritic spines.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080801

Mitochondrial matrix metalloproteinase activation decreases myocyte contractility in hyperhomocysteinemia.

American journal of physiology. Heart and circulatory physiology 20080801

Insulin-induced epidermal growth factor activation in vascular smooth muscle cells is ADAM-dependent.

Surgery 20080801

Latanoprost-induced changes in rat intraocular pressure: direct or indirect?

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20080801

The effect of therapeutic human serum drops on corneal stromal wound-healing activity.

Current eye research 20080801

Macrophages regulate tumor necrosis factor-alpha expression in adipocytes through the secretion of matrix metalloproteinase-3.

International journal of obesity (2005) 20080601

Acrolein-activated matrix metalloproteinase 9 contributes to persistent mucin production.

American journal of respiratory cell and molecular biology 20080401

Luteinizing hormone signaling in preovulatory follicles involves early activation of the epidermal growth factor receptor pathway.

Molecular endocrinology (Baltimore, Md.) 20080401

The highly specific platelet glycoprotein (GP) VI agonist trowaglerix impaired collagen-induced platelet aggregation ex vivo through matrix metalloproteinase-dependent GPVI shedding.

Journal of thrombosis and haemostasis : JTH 20080401

[Study on inhibitory effects of matrix metalloproteinase inhibitor on migration of cultured human lens epithelial cells].

[Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20080401

Endothelial dependence of matrix metalloproteinase-mediated vascular hyporeactivity caused by lipopolysaccharide.

European journal of pharmacology 20080317

Heparin-binding epidermal growth factor and Src family kinases in proliferation of renal epithelial cells.

American journal of physiology. Renal physiology 20080301

Human T cells stimulate fibroblast-mediated degradation of extracellular matrix in vitro.

Clinical and experimental immunology 20080201

Characterization of the cell membrane-associated products of the Neuregulin 4 gene.

Oncogene 20080124

Potential protective effect of fresh grown unicellular green algae component (resilient factor) against PMA- and UVB-induced MMP1 expression in skin fibroblasts.

European journal of dermatology : EJD 20080101

Actin polymerization modulates CD44 surface expression, MMP-9 activation, and osteoclast function.

Journal of cellular physiology 20071201

Rapid determination of enzyme kinetics from fluorescence: overcoming the inner filter effect.

Analytical biochemistry 20071201

VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt dependent pathway to modulate Tie2 signaling.

Arteriosclerosis, thrombosis, and vascular biology 20071201

Leptin stimulates endothelin-1 expression via extracellular signal-regulated kinase by epidermal growth factor receptor transactivation in rat aortic smooth muscle cells.

European journal of pharmacology 20071114

Differential modulation of Alzheimer's disease amyloid beta-peptide accumulation by diverse classes of metal ligands.

The Biochemical journal 20071101

Ligand binding rapidly induces disulfide-dependent dimerization of glycoprotein VI on the platelet plasma membrane.

The Journal of biological chemistry 20071019

Shedding of the urinary biomarker kidney injury molecule-1 (KIM-1) is regulated by MAP kinases and juxtamembrane region.

Journal of the American Society of Nephrology : JASN 20071001

Discovery and characterization of a novel inhibitor of matrix metalloprotease-13 that reduces cartilage damage in vivo without joint fibroplasia side effects.

The Journal of biological chemistry 20070921

Characterisation of endothelin converting enzyme-1 shedding from endothelial cells.

FEBS letters 20070918

Membrane-bound heparin-binding epidermal growth factor like growth factor regulates E-cadherin expression in pancreatic carcinoma cells.

Cancer research 20070915

Complex regulation of pulmonary inflammation and fibrosis by CCL18.

The American journal of pathology 20070801

Targeting host cell furin proprotein convertases as a therapeutic strategy against bacterial toxins and viral pathogens.

The Journal of biological chemistry 20070720

Simultaneous presence of unsaturation and long alkyl chain at P'1 of Ilomastat confers selectivity for gelatinase A (MMP-2) over gelatinase B (MMP-9) inhibition as shown by molecular modelling studies.

Bioorganic & medicinal chemistry 20070715

Fluorescent substrates for the proteinases ADAM17, ADAM10, ADAM8, and ADAM12 useful for high-throughput inhibitor screening.

Analytical biochemistry 20070715

Lutropin/choriogonadotropin stimulate the proliferation of primary cultures of rat Leydig cells through a pathway that involves activation of the extracellularly regulated kinase 1/2 cascade.

Endocrinology 20070701

Controlled shedding of platelet glycoprotein (GP)VI and GPIb-IX-V by ADAM family metalloproteinases.

Journal of thrombosis and haemostasis : JTH 20070701

Depolarization-induced, glutamate receptor-mediated, and transactivation-dependent extracellular-signal regulated kinase phosphorylation in cultured cerebellar granule neurons.

Neuroscience 20070629

Processing of Reelin by embryonic neurons is important for function in tissue but not in dissociated cultured neurons.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20070418

Protein kinase C activity mediates LH-induced ErbB/Erk signaling in differentiated hen granulosa cells.

Reproduction (Cambridge, England) 20070401

Extracellular signal-regulated kinase activation by parathyroid hormone in distal tubule cells.

American journal of physiology. Renal physiology 20070301

Functional corpora lutea are formed in matrix metalloproteinase inhibitor-treated plasminogen-deficient mice.

Endocrinology 20070301

Big ET-1 processing into vasoactive peptides in arteries and veins.

Vascular pharmacology 20070101

gamma-Aminbuturic acid A receptor mitigates homocysteine-induced endothelial cell permeability.

Endothelium : journal of endothelial cell research 20070101

Methylmercury induces activation of Notch signaling.

Neurotoxicology 20061201

Transmigration: a new property of mature multinucleated osteoclasts.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20061201

Differentiated thyroid cancer cell invasion is regulated through epidermal growth factor receptor-dependent activation of matrix metalloproteinase (MMP)-2/gelatinase A.

Endocrine-related cancer 20061201

Effects of alpha1D-adrenergic receptors on shedding of biologically active EGF in freshly isolated lacrimal gland epithelial cells.

American journal of physiology. Cell physiology 20061101

GnRH actions on rat preovulatory follicles are mediated by paracrine EGF-like factors.

Molecular reproduction and development 20061001

Kinin modulation of conventional outflow facility in the bovine eye.

Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20061001

Matrix metalloproteinases promote inflammation and fibrosis in asbestos-induced lung injury in mice.

American journal of respiratory cell and molecular biology 20060901

TIMP-1/MMP-9 imbalance in brain edema in rats with fulminant hepatic failure.

The Journal of surgical research 20060801

Relative contribution of matrix metalloprotease and cysteine protease activities to cytokine-stimulated articular cartilage degradation.

Osteoarthritis and cartilage 20060801

Matrix metalloproteinase inhibition attenuates aortic calcification.

Arteriosclerosis, thrombosis, and vascular biology 20060701

Plasminogen activation independent of uPA and tPA maintains wound healing in gene-deficient mice.

The EMBO journal 20060621

Metalloprotease inhibitors GM6001 and TAPI-0 inhibit the obligate intracellular human pathogen Chlamydia trachomatis by targeting peptide deformylase of the bacterium.

The Journal of biological chemistry 20060616

Matrix metalloproteinase-9 promotes neutrophil and T cell recruitment and migration in the postischemic liver.

Journal of leukocyte biology 20060601

Balamuthia mandrillaris exhibits metalloprotease activities.

FEMS immunology and medical microbiology 20060601

Metalloprotease-dependent amphiregulin release mediates tumor necrosis factor-alpha-induced IL-8 secretion in the human airway epithelial cell line NCI-H292.

Life sciences 20060522

Lysophosphatidic acid-induced effects in human colon carcinoma DLD1 cells are partially dependent on transactivation of epidermal growth factor receptor.

The Journal of surgical research 20060501

Transcriptional up-regulation of MMP12 and MMP13 by asbestos occurs via a PKCdelta-dependent pathway in murine lung.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060501

Src homology 2-containing phosphotyrosine phosphatase regulates endothelin-1-induced epidermal growth factor receptor transactivation in rat renal tubular cell NRK-52E.

Pflugers Archiv : European journal of physiology 20060401

Vascular responses to alpha1-adrenergic receptors in small rat mesenteric arteries depend on mitochondrial reactive oxygen species.

Arteriosclerosis, thrombosis, and vascular biology 20060401

PAR-type thrombin receptors in renal carcinoma cells: PAR1-mediated EGFR activation promotes cell migration.

Oncology reports 20060401

The death of human platelets during incubation in citrated plasma involves shedding of CD42b and aggregation of dead platelets.

Thrombosis and haemostasis 20060101

NCAM140 stimulates integrin-dependent cell migration by ectodomain shedding.

Journal of neurochemistry 20051201

Combining in silico tools and NMR data to validate protein-ligand structural models: application to matrix metalloproteinases.

Journal of medicinal chemistry 20051201

Activation of matrix metalloproteinase-9 via neuronal nitric oxide synthase contributes to NMDA-induced retinal ganglion cell death.

Investigative ophthalmology & visual science 20051201

Filamin is essential for shedding of the transmembrane serine protease, epithin.

EMBO reports 20051101

Angiotensin II activates matrix metalloproteinase type II and mimics age-associated carotid arterial remodeling in young rats.

The American journal of pathology 20051101

Shedding of the amyloid precursor protein-like protein APLP2 by disintegrin-metalloproteinases.

The FEBS journal 20051101

Transactivation of epidermal growth factor receptor is involved in leptin-induced activation of janus-activated kinase 2 and extracellular signal-regulated kinase 1/2 in human gastric cancer cells.

Cancer research 20051015

Modulation of conventional outflow facility by the adenosine A1 agonist N6-cyclohexyladenosine.

Investigative ophthalmology & visual science 20051001

Matrix metalloproteinases mediate beta-adrenergic receptor-stimulated apoptosis in adult rat ventricular myocytes.

American journal of physiology. Cell physiology 20050701

Functional selectivity of G protein signaling by agonist peptides and thrombin for the protease-activated receptor-1.

The Journal of biological chemistry 20050701

Selective inhibition of TNF-alpha-induced activation of mitogen-activated protein kinases and metastatic activities by gefitinib.

British journal of cancer 20050509

Epidermal growth factor receptor-dependent and -independent pathways in hydrogen peroxide-induced mitogen-activated protein kinase activation in cardiomyocytes and heart fibroblasts.

The Journal of pharmacology and experimental therapeutics 20050301

Metalloproteinases mediate mucin 5AC expression by epidermal growth factor receptor activation.

American journal of respiratory and critical care medicine 20050215

Epidermal growth factor family members: endogenous mediators of the ovulatory response.

Endocrinology 20050101

Relaxin's induction of metalloproteinases is associated with the loss of collagen and glycosaminoglycans in synovial joint fibrocartilaginous explants.

Arthritis research & therapy 20050101

Effect of a matrix metalloproteinase activity and TNF-alpha converting enzyme inhibitor on intra-abdominal adhesions.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20050101

Structure-based virtual screening and biological evaluation of potent and selective ADAM12 inhibitors.

Bioorganic & medicinal chemistry letters 20041220

Narrow-band ultraviolet-B stimulates proliferation and migration of cultured melanocytes.

Experimental dermatology 20041201

Kinetics of vascular normalization by VEGFR2 blockade governs brain tumor response to radiation: role of oxygenation, angiopoietin-1, and matrix metalloproteinases.

Cancer cell 20041201

Transactivation of epidermal growth factor receptor mediates catecholamine-induced growth of vascular smooth muscle.

Circulation research 20041112

TIMP-1 stimulates proliferation of human aortic smooth muscle cells and Ras effector pathways.

Biochemical and biophysical research communications 20041105

Alpha lipoic acid inhibits human T-cell migration: implications for multiple sclerosis.

Journal of neuroscience research 20041101

Down-regulated expression of A disintegrin and metalloproteinase with thrombospondin-like repeats-1 by progesterone receptor antagonist is associated with impaired expansion of porcine cumulus-oocyte complexes.

Endocrinology 20041001

Matrix metalloproteinase inhibitor GM 6001 attenuates keratinocyte migration, contraction and myofibroblast formation in skin wounds.

Experimental cell research 20041001

Opioid control of MAP kinase cascade.

European journal of pharmacology 20041001

Effect of MMP/ADAM inhibitors on goblet cell hyperplasia in cultured human bronchial epithelial cells.

Bioscience, biotechnology, and biochemistry 20041001

The role of matrix metalloproteinases in vascular function: implications for normal pregnancy and pre-eclampsia.

BJOG : an international journal of obstetrics and gynaecology 20040901

Minocycline exerts multiple inhibitory effects on vascular endothelial growth factor-induced smooth muscle cell migration: the role of ERK1/2, PI3K, and matrix metalloproteinases.

Circulation research 20040820

EGF-Like domain of tenascin-C is proapoptotic for cultured smooth muscle cells.

Arteriosclerosis, thrombosis, and vascular biology 20040801

Evidence for disulfide involvement in the regulation of intramolecular autolytic processing by human adamalysin19/ADAM19.

Experimental cell research 20040801

Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist.

Journal of immunology (Baltimore, Md. : 1950) 20040801

Release of soluble CD40L from platelets is regulated by glycoprotein IIb/IIIa and actin polymerization.

Journal of the American College of Cardiology 20040616

Heparin-binding epidermal growth factor cleavage mediates zinc-induced epidermal growth factor receptor phosphorylation.

American journal of respiratory cell and molecular biology 20040401

Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface.

Journal of cell science 20040401

Mechanisms and kinetics of glycosaminoglycan release following in vitro cartilage injury.

Arthritis and rheumatism 20040301

Tissue inhibitor of metalloproteinase-1 stimulates proliferation of human cancer cells by inhibiting a metalloproteinase.

British journal of cancer 20040126

Role of matrix metalloproteinases in delayed neuronal damage after transient global cerebral ischemia.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20040121

Tetrahydroisoquinoline based sulfonamide hydroxamates as potent matrix metalloproteinase inhibitors.

Bioorganic & medicinal chemistry letters 20040105

Ovarian carcinoma spheroids disaggregate on type I collagen and invade live human mesothelial cell monolayers.

Clinical & experimental metastasis 20040101

Essential role for vascular gelatinase activity in relaxin-induced renal vasodilation, hyperfiltration, and reduced myogenic reactivity of small arteries.

Circulation research 20031212

Gamma-aminobutyric acid as a promoting factor of cancer metastasis; induction of matrix metalloproteinase production is potentially its underlying mechanism.

Cancer research 20031201

Galardin (GM 6001), a broad-spectrum matrix metalloproteinase inhibitor, blocks bombesin- and LPA-induced EGF receptor transactivation and DNA synthesis in rat-1 cells.

Experimental cell research 20031101

Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration.

Developmental cell 20031001

MMPs inhibitors: new succinylhydroxamates with selective inhibition of MMP-2 over MMP-3.

Bioorganic & medicinal chemistry letters 20030901

Tamoxifen induces apoptosis in Fas+ tumor cells by upregulating the expression of Fas ligand.

Cancer chemotherapy and pharmacology 20030401

Glucagon-like peptide 1 induces pancreatic beta-cell proliferation via transactivation of the epidermal growth factor receptor.

Diabetes 20030101

Establishment of an in vitro assay to measure the invasion of ovarian carcinoma cells through mesothelial cell monolayers.

Clinical & experimental metastasis 20030101

Matrix metalloproteinases are not involved in early brain edema formation after cardiac arrest in rats.

Acta neurochirurgica. Supplement 20030101

Decreased expression of membrane IL-5 receptor alpha on human eosinophils: II. IL-5 down-modulates its receptor via a proteinase-mediated process.

Journal of immunology (Baltimore, Md. : 1950) 20021201

In vitro migration of melanoblasts requires matrix metalloproteinase-2: implications to vitiligo therapy by photochemotherapy.

Pigment cell research 20021201

Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration.

The Journal of biological chemistry 20021018

Metalloproteases and guidance of retinal axons in the developing visual system.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20020915

TNF-alpha mediates chemokine and cytokine expression and renal injury in cisplatin nephrotoxicity.

The Journal of clinical investigation 20020915

Transforming growth factor-beta1 modulates matrix metalloproteinase-9 production through the Ras/MAPK signaling pathway in transformed keratinocytes.

Biochemical and biophysical research communications 20020816

Synthetic matrix metalloproteinase inhibitors inhibit growth of established breast cancer osteolytic lesions and prolong survival in mice.

Clinical cancer research : an official journal of the American Association for Cancer Research 20020601

Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-beta and PDGF-BB.

American journal of physiology. Heart and circulatory physiology 20020201

Matrix metalloproteinases: a role in the contraction of vitreo-retinal scar tissue.

The American journal of pathology 20011001

Mutation analysis of membrane type-1 matrix metalloproteinase (MT1-MMP). The role of the cytoplasmic tail Cys(574), the active site Glu(240), and furin cleavage motifs in oligomerization, processing, and self-proteolysis of MT1-MMP expressed in breast carcinoma cells.

The Journal of biological chemistry 20010713

PECAM-1 shedding during apoptosis generates a membrane-anchored truncated molecule with unique signaling characteristics.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010201

Keratinocyte-driven contraction of reconstructed human skin.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20010101