Home Other Building Blocks (S)-2-Guanidinosuccinic acid

(S)-2-Guanidinosuccinic acid

CAS No.:
6133-30-8
Catalog Number:
AG0034ZD
Molecular Formula:
C5H9N3O4
Molecular Weight:
175.1427
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
10mg
98%
1 week
United States
$126
- +
50mg
98%
1 week
United States
$223
- +
100mg
98%
1 week
United States
$307
- +
Product Description
Catalog Number:
AG0034ZD
Chemical Name:
(S)-2-Guanidinosuccinic acid
CAS Number:
6133-30-8
Molecular Formula:
C5H9N3O4
Molecular Weight:
175.1427
MDL Number:
MFCD00055819
IUPAC Name:
(2S)-2-(diaminomethylideneamino)butanedioic acid
InChI:
InChI=1S/C5H9N3O4/c6-5(7)8-2(4(11)12)1-3(9)10/h2H,1H2,(H,9,10)(H,11,12)(H4,6,7,8)/t2-/m0/s1
InChI Key:
VVHOUVWJCQOYGG-REOHCLBHSA-N
SMILES:
NC(=N)N[C@H](C(=O)O)CC(=O)O
Properties
Complexity:
221  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
175.059g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
175.144g/mol
Monoisotopic Mass:
175.059g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
139A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-2  
Literature
Title Journal
Metabolomics with LC-QTOF-MS permits the prediction of disease stage in aortic abdominal aneurysm based on plasma metabolic fingerprint. PloS one 20120101
[Analysis of transporter function and development to clinical application]. Seikagaku. The Journal of Japanese Biochemical Society 20110401
Simultaneous determination of guanidinosuccinic acid and guanidinoacetic acid in urine using high performance liquid chromatography/tandem mass spectrometry. Analytica chimica acta 20100916
Impact of increasing haemodialysis frequency versus haemodialysis duration on removal of urea and guanidino compounds: a kinetic analysis. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20090701
First indications demonstrating the preventive effects of NZ-419, a novel intrinsic antioxidant, on the initiation and/or progression of chronic renal failure in rats. Biological & pharmaceutical bulletin 20090701
Accumulation of methylguanidine and changes in guanidino compound levels in plasma, urine, and kidneys of furosemide-treated rats. Metabolism: clinical and experimental 20080601
Guanidino compounds after creatine supplementation in renal failure patients and their relation to inflammatory status. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20080401
Premature aging in uremia. Molecular and cellular biochemistry 20070401
Anisoin: a useful pre-chromatographic derivatization fluorogenic reagent for LC analysis of guanidino compounds. Journal of pharmaceutical and biomedical analysis 20060911
Biochemical validation of a rat model for polycystic kidney disease: comparison of guanidino compound profile with the human condition. Kidney international 20060601
Substrate specificity of the human renal sodium dicarboxylate cotransporter, hNaDC-3, under voltage-clamp conditions. American journal of physiology. Renal physiology 20050401
GSA: behavioral, histological, electrophysiological and neurochemical effects. Physiology & behavior 20050215
[Guanidino compounds derivatives (guanidinosuccinic acid, guanidinoacetic acid)]. Nihon rinsho. Japanese journal of clinical medicine 20041101
Effect of NaCN on currents evoked by uremic retention solutes in dissociated mouse neurons. Brain research 20040515
Involvement of voltage- and ligand-gated Ca2+ channels in the neuroexcitatory and synergistic effects of putative uremic neurotoxins. Kidney international 20030501
Inhibition of arginine synthesis by urea: a mechanism for arginine deficiency in renal failure which leads to increased hydroxyl radical generation. Molecular and cellular biochemistry 20030201
Methyl group deficiency and guanidino production in uremia. Molecular and cellular biochemistry 20030201
Methyl group deficiency States. Nephron 20020901
Long-term effect of partial nephrectomy on biological parameters, kidney histology, and guanidino compound levels in mice. Metabolism: clinical and experimental 20011201
Influence of 72% injury in one kidney on several organs involved in guanidino compound metabolism: a time course study. Pflugers Archiv : European journal of physiology 20010701
Role of nitric oxide in the synthesis of guanidinosuccinic acid, an activator of the N-methyl-D-aspartate receptor. Kidney international. Supplement 20010201
Erythrocyte transketolase activity and guanidino compounds in hemodialysis patients. Kidney international. Supplement 20010201
Properties