Home Other Building Blocks Gamma-linolenic acid

Gamma-linolenic acid

CAS No.:
506-26-3
Catalog Number:
AG0034YP
Molecular Formula:
C18H30O2
Molecular Weight:
278.4296
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
50mg
≥98%
1 week
United States
$83
- +
100mg
≥98%
1 week
United States
$97
- +
250mg
≥98%
1 week
United States
$143
- +
1g
≥98%
1 week
United States
$268
- +
Product Description
Catalog Number:
AG0034YP
Chemical Name:
Gamma-linolenic acid
CAS Number:
506-26-3
Molecular Formula:
C18H30O2
Molecular Weight:
278.4296
MDL Number:
MFCD00065718
IUPAC Name:
(6Z,9Z,12Z)-octadeca-6,9,12-trienoic acid
InChI:
InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h6-7,9-10,12-13H,2-5,8,11,14-17H2,1H3,(H,19,20)/b7-6-,10-9-,13-12-
InChI Key:
VZCCETWTMQHEPK-QNEBEIHSSA-N
SMILES:
CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O
UNII:
78YC2MAX4O
Properties
Complexity:
301  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
3  
Exact Mass:
278.225g/mol
Formal Charge:
0
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
278.436g/mol
Monoisotopic Mass:
278.225g/mol
Rotatable Bond Count:
13  
Topological Polar Surface Area:
37.3A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.9  
Literature
Title Journal
JNK implication in adipocyte-like cell death induced by chemotherapeutic drug cisplatin. The Journal of toxicological sciences 20150201
Protective effect of conjugated linolenic acid isomers present in vegetable oils against arsenite-induced renal toxicity in rat model. Nutrition (Burbank, Los Angeles County, Calif.) 20130601
A novel antidiabetic drug, fasiglifam/TAK-875, acts as an ago-allosteric modulator of FFAR1. PloS one 20130101
Reversal of experimental ethanol-induced liver steatosis by borage oil. Phytotherapy research : PTR 20121101
Histopathological study of evening primrose oil effects on experimental diabetic neuropathy. Ultrastructural pathology 20120801
Hypolipidemic activity in Sprague-Dawley rats and constituents of a novel natural vegetable oil from Cornus wilsoniana fruits. Journal of food science 20120801
Comparison of growth, serum biochemistries and n-6 fatty acid metabolism in rats fed diets supplemented with high-gamma-linolenic acid safflower oil or borage oil for 90 days. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120601
Regioisomer separation and identification of triacylglycerols containing vaccenic and oleic acids, and α- and γ-linolenic acids, in thermophilic cyanobacteria Mastigocladus laminosus and Tolypothrix sp. Phytochemistry 20120601
Transfollicular enhancement of gel containing cationic niosomes loaded with unsaturated fatty acids in rice (Oryza sativa) bran semi-purified fraction. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120601
Nutritional interventions to prevent and treat osteoarthritis. Part I: focus on fatty acids and macronutrients. PM & R : the journal of injury, function, and rehabilitation 20120501
High level accumulation of gamma linolenic acid (C18:3Δ6.9,12 cis) in transgenic safflower (Carthamus tinctorius) seeds. Transgenic research 20120401
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Composition of transgenic soybean seeds with higher γ-linolenic acid content is equivalent to that of conventional control. Journal of agricultural and food chemistry 20120307
Probiotics and dietary counselling targeting maternal dietary fat intake modifies breast milk fatty acids and cytokines. European journal of nutrition 20120301
The production of conjugated α-linolenic, γ-linolenic and stearidonic acids by strains of bifidobacteria and propionibacteria. Lipids 20120301
Effect of fish oil supplementation in pregnancy on the fatty acid composition of erythrocyte phospholipids and breast milk lipids. International journal of food sciences and nutrition 20120201
Polyunsaturated fatty acids induce modification in the lipid composition and the prostaglandin production of the conjunctival epithelium cells. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20120201
Isolation and functional characterization of polyunsaturated fatty acid elongase (AsELOVL5) gene from black seabream (Acanthopagrus schlegelii). Biotechnology letters 20120201
Supplementation in acute lung injury. JAMA 20120111
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Metabolomics of dietary fatty acid restriction in patients with phenylketonuria. PloS one 20120101
A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ. PloS one 20120101
Modifications of stearidonic acid soybean oil by enzymatic acidolysis for the production of human milk fat analogues. Journal of agricultural and food chemistry 20111228
Erythrocyte membrane phospholipid polyunsaturated fatty acids are related to plasma C-reactive protein and adiponectin in middle-aged German women and men. European journal of nutrition 20111201
Guidelines for specialized nutritional and metabolic support in the critically-ill patient: update. Consensus SEMICYUC-SENPE: hyperglycemia and diabetes mellitus. Nutricion hospitalaria 20111101
Pharmaconutrition in acute lung injury. JAMA 20111012
Enteral omega-3 fatty acid, gamma-linolenic acid, and antioxidant supplementation in acute lung injury. JAMA 20111012
Effect of an enteral diet enriched with eicosapentaenoic acid, gamma-linolenic acid and anti-oxidants on the outcome of mechanically ventilated, critically ill, septic patients. Clinical nutrition (Edinburgh, Scotland) 20111001
Production of γ-linolenic acid using a novel heterologous expression system in the oleaginous yeast Lipomyces kononenkoae. Biotechnology letters 20111001
Δ6-Desaturase from Mortierella alpina: cDNA cloning, expression, and phylogenetic analysis. Biotechnology letters 20111001
The effects of evening primrose oil on lipid peroxidation induced by subacute aflatoxin exposure in mice. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110901
Evidence for the efficacy of complementary and alternative medicines in the management of rheumatoid arthritis: a systematic review. Rheumatology (Oxford, England) 20110901
Effects of prefermented cereal-derived substrates (ground barley and rye bran) enriched with fungal γ-linolenic acid on rumen fermentation parameters and lipid metabolism in vitro. Journal of applied microbiology 20110901
The lipogenesis pathway as a cancer target. Journal of medicinal chemistry 20110825
Up-regulated desaturase and elongase gene expression promoted accumulation of polyunsaturated fatty acid (PUFA) but not long-chain PUFA in Lates calcarifer, a tropical euryhaline fish, fed a stearidonic acid- and γ-linoleic acid-enriched diet. Journal of agricultural and food chemistry 20110810
A-z of nutritional supplements: dietary supplements, sports nutrition foods and ergogenic aids for health and performance--part 23. British journal of sports medicine 20110801
Delta-6 desaturase from borage converts linoleic acid to gamma-linolenic acid in HEK293 cells. Biochemical and biophysical research communications 20110708
Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats. Journal of cardiovascular pharmacology 20110701
Fish oil is not the fix for acute lung injury. Critical care medicine 20110701
Status epilepticus associated with borage oil ingestion. Journal of medical toxicology : official journal of the American College of Medical Toxicology 20110601
Herbal therapy for treating rheumatoid arthritis. The Cochrane database of systematic reviews 20110216
Acute respiratory distress syndrome: use of specialized nutrients in pediatric patients and infants. Nutrition in clinical practice : official publication of the American Society for Parenteral and Enteral Nutrition 20110201
Molecular cloning and expression analysis of a delta 6-fatty acid desaturase gene from Rhizopus stolonifer strain YF6 which can accumulate high levels of gamma-linolenic acid. Journal of microbiology (Seoul, Korea) 20110201
Separation of γ-linolenic and other polyunsaturated fatty acids from Boraginaceae via supercritical CO2. Journal of separation science 20110101
Enteral nutrition with eicosapentaenoic acid, γ-linolenic acid and antioxidants in the early treatment of sepsis: results from a multicenter, prospective, randomized, double-blinded, controlled study: the INTERSEPT study. Critical care (London, England) 20110101
Australian children are not consuming enough long-chain omega-3 polyunsaturated fatty acids for optimal health. Nutrition (Burbank, Los Angeles County, Calif.) 20110101
Incorporation of n-3 PUFA and γ-linolenic acid in blood lipids and red blood cell lipids together with their influence on disease activity in patients with chronic inflammatory arthritis--a randomized controlled human intervention trial. Lipids in health and disease 20110101
MicroRNA profile of polyunsaturated fatty acid treated glioma cells reveal apoptosis-specific expression changes. Lipids in health and disease 20110101
Fish oil and sepsis: we still need more trials. Critical care (London, England) 20110101
Dietary supplementation of gamma-linolenic acid improves skin parameters in subjects with dry skin and mild atopic dermatitis. Journal of oleo science 20110101
Central composite design for the optimization of supercritical carbon dioxide fluid extraction of fatty acids from Borago officinalis L. flower. Journal of food science 20110101
Rationale and use of n-3 fatty acids in artificial nutrition. The Proceedings of the Nutrition Society 20101101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Fermentation process development of recombinant Hansenula polymorpha for gamma-linolenic acid production. Journal of microbiology and biotechnology 20101101
Co-expression of heterologous desaturase genes in Yarrowia lipolytica. New biotechnology 20100930
Antimicrobial activity of n-6, n-7 and n-9 fatty acids and their esters for oral microorganisms. Archives of oral biology 20100801
Antineoplastic effects of gamma linolenic Acid on hepatocellular carcinoma cell lines. Journal of clinical biochemistry and nutrition 20100701
Microbial production of conjugated gamma-linolenic acid from gamma-linolenic acid by Lactobacillus plantarum AKU 1009a. Journal of applied microbiology 20100601
Efficacy of blackcurrant oil soft capsule, a Chinese herbal drug, in hyperlipidemia treatment. Phytotherapy research : PTR 20100601
Changes in fatty acid profiles in testis and spermatozoa of red deer exposed to metal pollution. Reproductive toxicology (Elmsford, N.Y.) 20100601
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Reduction of 5-azacitidine induced skin reactions in MDS patients with evening primrose oil. Annals of hematology 20100401
Vitamin E and evening primrose oil for management of cyclical mastalgia: a randomized pilot study. Alternative medicine review : a journal of clinical therapeutic 20100401
Oxygen-induced expression of Delta(6)-, Delta(9)- and Delta(12)-desaturase genes modulates fatty acid composition in Mucor rouxii. Applied microbiology and biotechnology 20100301
Gamma-linolenic acid inhibits inflammatory responses by regulating NF-kappaB and AP-1 activation in lipopolysaccharide-induced RAW 264.7 macrophages. Inflammation 20100201
Fatty acid supplements improve respiratory, inflammatory and nutritional parameters in adults with cystic fibrosis. Archivos de bronconeumologia 20100201
Recent trends in the advanced analysis of bioactive fatty acids. Journal of pharmaceutical and biomedical analysis 20100120
The novel ruthenium-gamma-linolenic complex [Ru(2)(aGLA)(4)Cl] inhibits C6 rat glioma cell proliferation and induces changes in mitochondrial membrane potential, increased reactive oxygen species generation and apoptosis in vitro. Cell biochemistry and function 20100101
Barrier functionality and transport machineries of human ECV304 cells. Medical science monitor : international medical journal of experimental and clinical research 20100101
Borage oil in the treatment of atopic dermatitis. Nutrition (Burbank, Los Angeles County, Calif.) 20100101
Polyunsaturated fatty acids and atopic dermatitis. Nutrition (Burbank, Los Angeles County, Calif.) 20100101
Re: The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. JPEN. Journal of parenteral and enteral nutrition 20100101
Feeding stimulant in Cinnamomum camphora for the common bluebottle, Graphium sarpedon nipponum (Lepidoptera: Papilionidae). Zeitschrift fur Naturforschung. C, Journal of biosciences 20100101
Fatty acid composition in lipid fractions lengthwise the mycelium of Mortierella isabellina and lipid production by solid state fermentation. Bioresource technology 20091201
Clinical study of the effects on asthma-related QOL and asthma management of a medical food in adult asthma patients. Current medical research and opinion 20091201
Evening primrose oil supplementation increases citraturia and decreases other urinary risk factors for calcium oxalate urolithiasis. The Journal of urology 20091201
Evidence of effectiveness of herbal medicinal products in the treatment of arthritis. Part 2: Rheumatoid arthritis. Phytotherapy research : PTR 20091201
Comparison of various types of stationary phases in non-aqueous reversed-phase high-performance liquid chromatography-mass spectrometry of glycerolipids in blackcurrant oil and its enzymatic hydrolysis mixture. Journal of chromatography. A 20091120
Identification and characterization of a novel delta6-fatty acid desaturase gene from Rhizopus nigricans. Molecular biology reports 20091101
Assessment of anticoagulant effect of evening primrose oil. Pakistan journal of pharmaceutical sciences 20091001
Which complementary therapies can help patients with PMS? The Journal of family practice 20091001
Production of gamma-linolenic acid in Pichia pastoris by Expression of a delta-6 desaturase gene from Cunninghamella echinulata. Journal of microbiology and biotechnology 20091001
Efficacy of a 2-month dietary supplementation with polyunsaturated fatty acids in dry eye induced by scopolamine in a rat model. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20090801
The activity of lysosomal exoglycosidases in serum of alcohol-dependent men supplemented with borage oil enriched with vitamin E. Journal of medicinal food 20090801
Steady-state and time-resolved fluorescence studies of stripped Borage oil. Analytica chimica acta 20090730
Gamma-linolenic acid production of Mucor rouxii by solid-state fermentation using agricultural by-products. Letters in applied microbiology 20090701
Effect of dietary fatty acids on inflammatory gene expression in healthy humans. The Journal of biological chemistry 20090605
Gamma-linolenic acid modulates the response of multidrug-resistant K562 leukemic cells to anticancer drugs. Toxicology in vitro : an international journal published in association with BIBRA 20090601
Dietary n-3 and n-6 PUFA enhance DHA incorporation in retinal phospholipids without affecting PGE(1) and PGE (2) levels. Lipids 20090501
Gamma-linolenic acid induces apoptosis and lipid peroxidation in human chronic myelogenous leukemia K562 cells. Cell biology international 20090301
Intervention with flaxseed and borage oil supplements modulates skin condition in women. The British journal of nutrition 20090201
Application of response surface method for studying the role of dissolved oxygen and agitation speed on gamma-linolenic acid production. Applied biochemistry and biotechnology 20090101
Gamma-linolenic acid inhibits both tumour cell cycle progression and angiogenesis in the orthotopic C6 glioma model through changes in VEGF, Flt1, ERK1/2, MMP2, cyclin D1, pRb, p53 and p27 protein expression. Lipids in health and disease 20090101
Nutrition for the eye: different susceptibility of the retina and the lacrimal gland to dietary omega-6 and omega-3 polyunsaturated fatty acid incorporation. Ophthalmic research 20090101
Treatment of carpal tunnel syndrome with alpha-lipoic acid. European review for medical and pharmacological sciences 20090101
Effects of fatty acids on metabolism and cell growth of human colon cell lines of different transformation state. BioFactors (Oxford, England) 20090101
Activation of testicular orphan receptor 4 by fatty acids. Biochimica et biophysica acta 20090101
The use of alpha-lipoic acid (ALA), gamma linolenic acid (GLA) and rehabilitation in the treatment of back pain: effect on health-related quality of life. International journal of immunopathology and pharmacology 20090101
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[Effects of gamma linolenic acid on atherosclerosis induced by cholesterol-rich diet in rats]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20081201
Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity. PLoS genetics 20081101
Magnesium stimulates renal phosphate reabsorption. American journal of physiology. Renal physiology 20081001
Stability analysis of zinc oxide-nanoencapsulated conjugated linoleic acid and gamma-linolenic acid. Journal of food science 20081001
Gamma-linolenic acid production by Cunninghamella echinulata growing on complex organic nitrogen sources. Bioresource technology 20080901
Consumption of functional fermented milk containing borage oil, green tea and vitamin E enhances skin barrier function. Experimental dermatology 20080801
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Regioisomeric structure determination of alpha- and gamma-linolenoyldilinoleoylglycerol in blackcurrant seed oil by silver ion high-performance liquid chromatography and mass spectrometry. Analytical chemistry 20080801
Purification and identification of bovine cheese whey fatty acids exhibiting in vitro antifungal activity. Journal of dairy science 20080701
Fatty acid composition of serum lipid classes in mice following allergic sensitisation with or without dietary docosahexaenoic acid-enriched fish oil substitution. The British journal of nutrition 20080601
LC/ESR/MS study of spin trapped carbon-centred radicals formed from in vitro lipoxygenase-catalysed peroxidation of gamma-linolenic acid. Free radical research 20080501
Evaluation of inoculum performance for enhancing gamma-linolenic acid production from Mucor rouxii. Letters in applied microbiology 20080401
Screening of 397 chemicals and development of a quantitative structure--activity relationship model for androgen receptor antagonism. Chemical research in toxicology 20080401
Monoepoxy octadecadienoates and monoepoxy octadecatrienoates 1: NMR spectral characterization. Chemistry and physics of lipids 20080401
Cholesterol-induced stimulation of platelet aggregation is prevented by a hempseed-enriched diet. Canadian journal of physiology and pharmacology 20080401
[Prepared evening primrose oil microspheres by spray drying]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20080401
Enhanced biomass and gamma-linolenic acid production of mutant strain Arthrospira platensis. Journal of microbiology and biotechnology 20080301
Co-supplementation of healthy women with fish oil and evening primrose oil increases plasma docosahexaenoic acid, gamma-linolenic acid and dihomo-gamma-linolenic acid levels without reducing arachidonic acid concentrations. The British journal of nutrition 20080201
The impact of a medical food containing gammalinolenic and eicosapentaenoic acids on asthma management and the quality of life of adult asthma patients. Current medical research and opinion 20080201
Down the primrose path: petechiae in a neonate exposed to herbal remedy for parturition. The Journal of pediatrics 20080101
Linoleic acid metabolite levels and transepidermal water loss in children with atopic dermatitis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080101
Metabolism of omega-6 polyunsaturated fatty acids in women with dysmenorrhea. Asia Pacific journal of clinical nutrition 20080101
[Ankylosing Spondylitis and convenient nutrition]. Wiener medizinische Wochenschrift (1946) 20080101
[Activity of NAD-dependent isocitrate dehydrogenase, isocitrate lyase, and malate dehydrogenase in Mucor circinelloides var. lusitanicus INMI under different modes of nitrogen supply]. Mikrobiologiia 20080101
[Metabolic characteristics and lipid composition of yeastlike cells and mycelium of Mucor circinelloides var. lusitanicus INMI grown at a high glucose content in the medium]. Mikrobiologiia 20080101
[Effects of conditions for obtaining sporangiospores of the inoculum on the morphology and productivity of the fungus Mucor circinelloides var. lusitanicus 12 M, a producer of gamma-linolenic acid]. Prikladnaia biokhimiia i mikrobiologiia 20080101
The use of an inflammation-modulating diet in patients with acute lung injury or acute respiratory distress syndrome: a meta-analysis of outcome data. JPEN. Journal of parenteral and enteral nutrition 20080101
Nutrition therapy for acute respiratory distress syndrome. JPEN. Journal of parenteral and enteral nutrition 20080101
Modified EN support for patients with acute respiratory distress syndrome. JPEN. Journal of parenteral and enteral nutrition 20080101
The influence of feeding linoleic, gamma-linolenic and docosahexaenoic acid rich oils on rat brain tumor fatty acids composition and fatty acid binding protein 7 mRNA expression. Lipids in health and disease 20080101
Evening primrose oil is effective in atopic dermatitis: a randomized placebo-controlled trial. Indian journal of dermatology, venereology and leprology 20080101
A diet enriched in eicosapentanoic acid, gamma-linolenic acid and antioxidants in the prevention of new pressure ulcer formation in critically ill patients with acute lung injury: A randomized, prospective, controlled study. Clinical nutrition (Edinburgh, Scotland) 20071201
Specific effects of gamma-linolenic, eicosapentaenoic, and docosahexaenoic ethyl esters on bone post-ovariectomy in rats. Calcified tissue international 20071201
Clinical effects of undershirts coated with borage oil on children with atopic dermatitis: a double-blind, placebo-controlled clinical trial. The Journal of dermatology 20071201
A 5-month open study with long-chain polyunsaturated fatty acids in dyslexia. Journal of medicinal food 20071201
Anti-wrinkling effects of the mixture of vitamin C, vitamin E, pycnogenol and evening primrose oil, and molecular mechanisms on hairless mouse skin caused by chronic ultraviolet B irradiation. Photodermatology, photoimmunology & photomedicine 20071001
Low intensity laser therapy is comparable to bromocriptine-evening primrose oil for the treatment of cyclical mastalgia in Egyptian females. Tanzania health research bulletin 20070901
[Influence of methyl esterification on the ultraviolet absorption of gamma-linolenic acid]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070901
The safety of evening primrose oil in epilepsy. Prostaglandins, leukotrienes, and essential fatty acids 20070801
Gamma-linolenic acid therapy of human glioma-a review of in vitro, in vivo, and clinical studies. Medical science monitor : international medical journal of experimental and clinical research 20070701
Enhanced tight junction function in human breast cancer cells by antioxidant, selenium and polyunsaturated lipid. Journal of cellular biochemistry 20070501
Effect of oral linoleic and gamma-linolenic acid on meibomian gland dysfunction. Cornea 20070401
Conjugated linoleic acid and black currant seed oil in the treatment of canine atopic dermatitis: a preliminary report. Veterinary journal (London, England : 1997) 20070301
High-quality enteral nutrition essential for reducing morbidity and mortality in acute care patients. Critical care medicine 20070301
Saving lives in severe sepsis with the help of enteral nutrition. Critical care medicine 20070301
Long-chain polyunsaturated fatty acids and the pathophysiology of myalgic encephalomyelitis (chronic fatigue syndrome). Journal of clinical pathology 20070201
[Cloning and expression of a delta6-fatty acid desaturase gene from Rhizopus stolonifer in Saccharomyces cervisiae]. Wei sheng wu xue bao = Acta microbiologica Sinica 20070201
TRPV1 is a novel target for omega-3 polyunsaturated fatty acids. The Journal of physiology 20070115
High-performance liquid chromatography with nuclear magnetic resonance detection--A method for quantification of alpha- and gamma-linolenic acids in their mixtures with free fatty acids. Journal of chromatography. A 20070112
A randomised cross-over trial in healthy adults indicating improved absorption of omega-3 fatty acids by pre-emulsification. Nutrition journal 20070101
Undershirts coated with borage oil alleviate the symptoms of atopic dermatitis in children. European journal of dermatology : EJD 20070101
[Biology of essential fatty acids (EFA)]. Przeglad lekarski 20070101
[The gamma-linolenic acid (GLA)--the therapeutic value]. Przeglad lekarski 20070101
Dietary effect of gamma-linolenic acid on the lipid profile of rat fed erucic acid rich oil. Journal of oleo science 20070101
Production of polyunsaturated fatty acids in transgenic plants. Biotechnology & genetic engineering reviews 20070101
Changes in the content of gamma-linolenic C18:3 (n-6) and stearidonic C18:4 (n-3) acids in developing seeds of viper's bugloss Echium vulgare L. Acta biochimica Polonica 20070101
Lipids of Cunninghamella echinulata with emphasis to gamma-linolenic acid distribution among lipid classes. Applied microbiology and biotechnology 20061201
Properties of cholesterol-reduced butter made with beta-cyclodextrin and added evening primrose oil and phytosterols. Journal of dairy science 20061201
A nutritional strategy to improve oxygenation and decrease morbidity in patients who have acute respiratory distress syndrome. Respiratory care clinics of North America 20061201
Tumoricidal and anti-angiogenic actions of gamma-linolenic acid and its derivatives. Current pharmaceutical biotechnology 20061201
A meta-analysis of randomized, placebo-controlled clinical trials of Efamol evening primrose oil in atopic eczema. Where do we go from here in light of more recent discoveries? Current pharmaceutical biotechnology 20061201
Gamma linolenic acid: an antiinflammatory omega-6 fatty acid. Current pharmaceutical biotechnology 20061201
Conjugated linoleic acid, unlike other unsaturated fatty acids, strongly induces glutathione synthesis without any lipoperoxidation. The British journal of nutrition 20061101
Revealing the complementation of ferredoxin by cytochrome b (5) in the Spirulina- (6)-desaturation reaction by N-terminal fusion and co-expression of the fungal-cytochrome b (5) domain and Spirulina- (6)-acyl-lipid desaturase. Applied microbiology and biotechnology 20061001
Fatty acid-induced toxicity and neutral lipid accumulation in insulin-producing RINm5F cells. Toxicology in vitro : an international journal published in association with BIBRA 20061001
Systematic study on ROS production induced by oleic, linoleic, and gamma-linolenic acids in human and rat neutrophils. Free radical biology & medicine 20061001
Effects of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants in mechanically ventilated patients with severe sepsis and septic shock. Critical care medicine 20060901
Enteral therapy to decrease morbidity and improve survival in acute respiratory distress syndrome: its time has come. Critical care medicine 20060901
Distribution and metabolism of dihomo-gamma-linolenic acid (DGLA, 20:3n-6) by oral supplementation in rats. Bioscience, biotechnology, and biochemistry 20060901
Comparative effect of gromwell (Lithospermum erythrorhizon) extract and borage oil on reversing epidermal hyperproliferation in guinea pigs. Bioscience, biotechnology, and biochemistry 20060901
Induction of apoptosis in K562/ADM cells by gamma-linolenic acid involves lipid peroxidation and activation of caspase-3. Chemico-biological interactions 20060825
Synergistic regulation of endothelial tight junctions by antioxidant (Se) and polyunsaturated lipid (GLA) via Claudin-5 modulation. Journal of cellular biochemistry 20060801
Therapeutic effect of topical gamma-linolenic acid on refractory uremic pruritus. American journal of kidney diseases : the official journal of the National Kidney Foundation 20060701
Self-reported health problems in young male subjects supplementing their diet with oils rich in eicosapentaenoic, gamma-linolenic and stearidonic acids. Prostaglandins, leukotrienes, and essential fatty acids 20060701
Effect of diets enriched in Delta6 desaturated fatty acids (18:3n-6 and 18:4n-3), on growth, fatty acid composition and highly unsaturated fatty acid synthesis in two populations of Arctic charr (Salvelinus alpinus L.). Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20060601
Re: Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. Journal of the National Cancer Institute 20060517
Induction of renal cytochrome P450 arachidonic acid epoxygenase activity by dietary gamma-linolenic acid. The Journal of pharmacology and experimental therapeutics 20060501
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Benefit of an enteral diet enriched with eicosapentaenoic acid and gamma-linolenic acid in ventilated patients with acute lung injury. Critical care medicine 20060401
Acute lung injury and nutritional support. Critical care medicine 20060401
Dietary gamma-linolenate attenuates tumor growth in a rodent model of prostatic adenocarcinoma via suppression of elevated generation of PGE(2) and 5S-HETE. Prostaglandins, leukotrienes, and essential fatty acids 20060401
Effect of gamma-linolenic acid and prostaglandins E1 on gamma-radiation and chemical-induced genetic damage to the bone marrow cells of mice. Prostaglandins, leukotrienes, and essential fatty acids 20060301
Impact of early dietary gamma-linolenic acid supplementation on atopic eczema in infancy. Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20060301
Gamma-linolenic acid from Cape Verdian Boraginaceae. Natural product research 20060101
Systemic omega-6 essential fatty acid treatment and pge1 tear content in Sjögren's syndrome patients. Investigative ophthalmology & visual science 20051201
A 3-month double-blind randomised study comparing an olive oil- with a soyabean oil-based intravenous lipid emulsion in home parenteral nutrition patients. The British journal of nutrition 20051201
Effect of gamma-linolenic acid on the transcriptional activity of the Her-2/neu (erbB-2) oncogene. Journal of the National Cancer Institute 20051102
Preferential pi-pi complexation between tamoxifen and borage oil/gamma linolenic acid: transcutaneous delivery and NMR spectral modulation. International journal of pharmaceutics 20050930
Modification of skin composition by conjugated linoleic acid alone or with combination of other fatty acids in mice. The British journal of nutrition 20050801
Black currant seed oil and fish oil supplements differ in their effects on fatty acid profiles of plasma lipids, and concentrations of serum total and lipoprotein lipids, plasma glucose and insulin. The Journal of nutritional biochemistry 20050601
The Influence of long-chain polyunsaturated fatty acids on total lipid fatty acid composition of a canine mastocytoma cell line. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20050601
Substrate specificity and preference of Delta6-desaturase of Mucor rouxii. FEBS letters 20050509
N-6 polyunsaturated fatty acids confer hemodynamic stability in an experimental model of multiple trauma. Prostaglandins, leukotrienes, and essential fatty acids 20050501
15-lipoxygenase metabolites of gamma-linolenic acid/eicosapentaenoic acid suppress growth and arachidonic acid metabolism in human prostatic adenocarcinoma cells: possible implications of dietary fatty acids. Prostaglandins, leukotrienes, and essential fatty acids 20050501
Evening primrose oil effects on osteoclasts during tooth movement. The Angle orthodontist 20050501
Gamma-Linolenic acid regulates the expression and secretion of SPARC in human cancer cells. Prostaglandins, leukotrienes, and essential fatty acids 20050401
Dietary fish and evening primrose oil with vitamin E effects on semen variables in cockerels. British poultry science 20050401
Regulation of reactive oxygen species (ROS) production by C18 fatty acids in Jurkat and Raji cells. Clinical science (London, England : 1979) 20050301
Is there clinical evidence supporting the use of botanical dietary supplements in children? The Journal of pediatrics 20050301
[Study on the encapsulation technique of high purity gamma-linolenic acid, part 1--saponification reaction and saponification value]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301
[Study on the encapsulation technique of high purity gamma-linolenic acid, part 1--Single factor, and two-factor tests for encapsulation process]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20050301
Cloning of delta6-desaturase from Mucor circinelloides and its high expression in Saccharomyces cerevisiae. Yi chuan xue bao = Acta genetica Sinica 20050301
Topical nonsteroidal anti-inflammatory drugs versus oil of evening primrose in the treatment of mastalgia. The surgeon : journal of the Royal Colleges of Surgeons of Edinburgh and Ireland 20050201
Inhibition of fatty acid synthase-dependent neoplastic lipogenesis as the mechanism of gamma-linolenic acid-induced toxicity to tumor cells: an extension to Nwankwo's hypothesis. Medical hypotheses 20050101
Free fatty acids regulate gut incretin glucagon-like peptide-1 secretion through GPR120. Nature medicine 20050101
A randomized multicenter study of gamolenic acid (Efamast) with and without antioxidant vitamins and minerals in the management of mastalgia. The breast journal 20050101
Molecular evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of an elongase. Lipids 20050101
Screening of bacterial associates of marine sponges for single cell oil and PUFA. Letters in applied microbiology 20050101
Effect of a combination of isoflavones and Actaea racemosa Linnaeus on climacteric symptoms in healthy symptomatic perimenopausal women: a 12-week randomized, placebo-controlled, double-blind study. Menopause (New York, N.Y.) 20050101
Single cell oil (SCO) production by Mortierella isabellina grown on high-sugar content media. Bioresource technology 20041201
Metabolic consequences of hypoxia from birth and dexamethasone treatment in the neonatal rat: comprehensive hepatic lipid and fatty acid profiling. Endocrinology 20041101
In-vitro transcutaneous delivery of tamoxifen and gamma-linolenic acid from borage oil containing ethanol and 1,8-cineole. The Journal of pharmacy and pharmacology 20041101
Alterations of mast cell mediator production and release by gamma-linolenic and docosahexaenoic acid. Veterinary dermatology 20041001
The effect of six different C18 fatty acids on body fat and energy metabolism in mice. The British journal of nutrition 20040901
Suppression of cyclooxygenase-2 overexpression by 15S-hydroxyeicosatrienoic acid in androgen-dependent prostatic adenocarcinoma cells. International journal of cancer 20040820
Alteration of prostaglandin production and agonist responsiveness by n-6 polyunsaturated fatty acids in endometrial cells from late-gestation ewes. The Journal of endocrinology 20040801
[Heteologous expression of Mortierella isabellina delta6 -fatty acid desaturase gene in soybean]. Yi chuan xue bao = Acta genetica Sinica 20040801
Effect of long-term dietary supplementation of high-gamma-linolenic canola oil versus borage oil on growth, hematology, serum biochemistry, and N-6 fatty acid metabolism in rats. Journal of agricultural and food chemistry 20040616
Quantitative analysis of anti-inflammatory and radical scavenging triterpenoid esters in evening primrose oil. Journal of agricultural and food chemistry 20040602
The influence of different combinations of gamma-linolenic, stearidonic and eicosapentaenoic acids on the fatty acid composition of blood lipids and mononuclear cells in human volunteers. Prostaglandins, leukotrienes, and essential fatty acids 20040601
From bench to the clinic: gamma-linolenic acid therapy of human gliomas. Prostaglandins, leukotrienes, and essential fatty acids 20040601
Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression. Oncology reports 20040601
Overexpression and hyperactivity of breast cancer-associated fatty acid synthase (oncogenic antigen-519) is insensitive to normal arachidonic fatty acid-induced suppression in lipogenic tissues but it is selectively inhibited by tumoricidal alpha-linolenic and gamma-linolenic fatty acids: a novel mechanism by which dietary fat can alter mammary tumorigenesis. International journal of oncology 20040601
Nutrient supplementation with polyunsaturated fatty acids and micronutrients in rheumatoid arthritis: clinical and biochemical effects. European journal of clinical nutrition 20040601
The influence of different combinations of gamma-linolenic acid, stearidonic acid and EPA on immune function in healthy young male subjects. The British journal of nutrition 20040601
The use of dietary manipulation by parents of children with atopic dermatitis. The British journal of dermatology 20040601
A randomized, controlled study to evaluate the steroid sparing effect of essential fatty acid supplementation in the treatment of canine atopic dermatitis. Veterinary dermatology 20040601
[Prostaglandin/bradykinin]. Nihon rinsho. Japanese journal of clinical medicine 20040601
Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) is a selective estrogen-response modulator in human breast cancer cells: gamma-linolenic acid antagonizes estrogen receptor-dependent transcriptional activity, transcriptionally represses estrogen receptor expression and synergistically enhances tamoxifen and ICI 182,780 (Faslodex) efficacy in human breast cancer cells. International journal of cancer 20040510
Re: Packer RJ. Effects of radiotherapy on the brain. Med Pediatr Oncol 2003;41:448-449. Pediatric blood & cancer 20040501
Intracellular oxidation by human glioma cell populations: effect of arachidonic acid. Prostaglandins, leukotrienes, and essential fatty acids 20040501
Who and how many people are taking herbal supplements? A survey of 21,923 adults. International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20040501
[Progress on molecular biology of delta6-fatty acid desaturases]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040501
A trial of omega-3 fatty acids for prevention of hypertension. The American journal of cardiology 20040415
Eicosapentaenoic acid and gamma-linolenic acid increase hippocampal concentrations of IL-4 and IL-10 and abrogate lipopolysaccharide-induced inhibition of long-term potentiation. Prostaglandins, leukotrienes, and essential fatty acids 20040401
Gamma-linolenic acid prevents conjugated linoleic acid-induced fatty liver in mice. Nutrition (Burbank, Los Angeles County, Calif.) 20040401
Randomized, double-blind trial of long-chain polyunsaturated fatty acid supplementation with fish oil and borage oil in preterm infants. The Journal of pediatrics 20040401
Oral essential fatty acid supplementation in atopic dermatitis-a meta-analysis of placebo-controlled trials. The British journal of dermatology 20040401
Prevention and partial reversal of diabetes-induced changes in enteric nerves of the rat ileum by combined treatment with alpha-lipoic acid and evening primrose oil. Autonomic neuroscience : basic & clinical 20040331
Gamma-linolenic acid (GLA). Monograph. Alternative medicine review : a journal of clinical therapeutic 20040301
Simultaneous permeation of tamoxifen and gamma linolenic acid across excised human skin. Further evidence of the permeation of solvated complexes. International journal of pharmaceutics 20040301
Suppression of leukotriene B4 generation by ex-vivo neutrophils isolated from asthma patients on dietary supplementation with gammalinolenic acid-containing borage oil: possible implication in asthma. Clinical & developmental immunology 20040301
Fatty acid content and juice characteristics in black currant (Ribes nigrum L.) genotypes. Journal of agricultural and food chemistry 20040225
An aqueous formulation of gamma-linolenic acid with anti-proliferative action on human pancreatic cancer cell lines. Anti-cancer drugs 20040201
Identification and characterization of a novel Delta6-fatty acid desaturase gene from Rhizopus arrhizus. FEBS letters 20040102
Occlusion of infusion vessels on gamma-linolenic acid infusion. Prostaglandins, leukotrienes, and essential fatty acids 20040101
Effects of different dietary oils on inflammatory mediator generation and fatty acid composition in rat neutrophils. Metabolism: clinical and experimental 20040101
The clinical advantages of cold-pressed non-raffinated evening primrose oil over refined preparations. Medical hypotheses 20040101
Omega 3 oils and pregnancy. Midwifery today with international midwife 20040101
Lipase-catalyzed ethanolysis of borage oil: a kinetic study. Biotechnology progress 20040101
A retinoid X receptor (RXR)-selective retinoid reveals that RXR-alpha is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands. Breast cancer research : BCR 20040101
Repression of reserve lipid turnover in Cunninghamella echinulata and Mortierella isabellina cultivated in multiple-limited media. Journal of applied microbiology 20040101
Inhibition of 5-lipoxygenase induces cell death in anti-inflammatory fatty acid-treated HL-60 cells. JPEN. Journal of parenteral and enteral nutrition 20040101
[Expression of delta6-fatty acid desaturase gene from Mortierella alpina in Pichia pastoris]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20040101
Evening primrose oil for atopic dermatitis. BMJ (Clinical research ed.) 20031213
Efficacy and tolerability of borage oil in adults and children with atopic eczema: randomised, double blind, placebo controlled, parallel group trial. BMJ (Clinical research ed.) 20031213
Caspase-independent apoptosis induced by evening primrose extract in Ehrlich ascites tumor cells. Cancer letters 20031110
Fat facts and fallacies. Home healthcare nurse 20031101
Effects of dietary n-3 or n-6 fatty acids on interleukin-1beta-induced anxiety, stress, and inflammatory responses in rats. Journal of lipid research 20031001
Effect of linoleic acid and gamma-linolenic acid on tear production, tear clearance and on the ocular surface after photorefractive keratectomy. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20030701
Characterization of a heart-specific fatty acid transport protein. The Journal of biological chemistry 20030502
Herbal medicines for the treatment of rheumatoid arthritis: a systematic review. Rheumatology (Oxford, England) 20030501
Synthesis and isolation of trans-7,cis-9 octadecadienoic acid and other CLA isomers by base conjugation of partially hydrogenated gamma-linolenic acid. Lipids 20030501
Effects of dietary linseed, evening primrose or fish oils on fatty acid and prostaglandin E2 contents in the rat livers and 7,12-dimethylbenz[a]anthracene-induced tumours. Biochimica et biophysica acta 20030417
Treating hot flushes without hormone replacement therapy. The Journal of family practice 20030401
Diet and asthma: has the role of dietary lipids been overlooked in the management of asthma? Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20030401
Pilot study of dietary fatty acid supplementation in the treatment of adult periodontitis. Prostaglandins, leukotrienes, and essential fatty acids 20030301
Systemic linoleic and gamma-linolenic acid therapy in dry eye syndrome with an inflammatory component. Cornea 20030301
Inhibition of leukotriene synthesis, pharmacokinetics, and tolerability of a novel dietary fatty acid formulation in healthy adult subjects. Clinical therapeutics 20030301
Inhibition of leukotriene biosynthesis by a novel dietary fatty acid formulation in patients with atopic asthma: a randomized, placebo-controlled, parallel-group, prospective trial. Clinical therapeutics 20030301
[Expression of Mortierella isabellina delta6-fatty acid desaturase gene in gamma-linolenic acid production in transgenic tobacco]. Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20030301
Enteral nutrition with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants reduces alveolar inflammatory mediators and protein influx in patients with acute respiratory distress syndrome. Critical care medicine 20030201
Effect of gamma-linolenic acid or docosahexaenoic acid on tight junction permeability in intestinal monolayer cells and their mechanism by protein kinase C activation and/or eicosanoid formation. Nutrition (Burbank, Los Angeles County, Calif.) 20030201
Arachidonic acid-induced channel- and carrier-type ion transport across planar bilayer lipid membranes. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030201
Effects of high-gamma-linolenic acid canola oil compared with borage oil on reproduction, growth, and brain and behavioral development in mice. Lipids 20030201
Activation of peroxisome proliferator-activated receptor (PPAR)-gamma by 15S-hydroxyeicosatrienoic acid parallels growth suppression of androgen-dependent prostatic adenocarcinoma cells. Cancer letters 20030110
Epirubicin and meglumine gamma-linolenic acid: a logical choice of combination therapy for patients with superficial bladder carcinoma. Cancer 20030101
The effectiveness of treatments of diabetic autonomic neuropathy is not the same in autonomic nerves supplying different organs. Diabetes 20030101
Acyl-CoA thioesterase activity in human placental choriocarcinoma (BeWo), cells: effects of fatty acids. Prostaglandins, leukotrienes, and essential fatty acids 20030101
Production of gamma-linolenic acid by disrupted mycelia of Mortierella isabellina. Letters in applied microbiology 20030101
Botanicals and dietary supplements in diabetic peripheral neuropathy. The Journal of the American Board of Family Practice 20030101
Structural characterization of triacylglycerol in several oils containing gamma-linolenic acid. Bioscience, biotechnology, and biochemistry 20030101
Effect of enteral feeding with eicosapentaenoic acid, gamma-linolenic acid, and antioxidants on antioxidant status in patients with acute respiratory distress syndrome. JPEN. Journal of parenteral and enteral nutrition 20030101
Antioxidant status, lipoprotein profile and liver lipids in rats fed on high-cholesterol diet containing currant oil rich in n-3 and n-6 polyunsaturated fatty acids. Physiological research 20030101
Individual fatty acids influence cultured human liver cells differently when compared to plant oils. Anticancer research 20030101
Lipid peroxidation by Pseudomonas aeruginosa in the pathogenesis of nosocomial sepsis. Journal of postgraduate medicine 20030101
Synergistic activity of gamma-linolenic acid and cytotoxic drugs against pancreatic adenocarcinoma cell lines. Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20030101
Antioxidant properties of captopril in vitro. Acta poloniae pharmaceutica 20030101
Evening primrose oil and fish oil for severe chronic mastalgia: a randomized, double-blind, controlled trial. American journal of obstetrics and gynecology 20021101
Highly unsaturated fatty acid induced tumour regression in glioma pharmacodynamics and bioavailability of gamma linolenic acid in an implantation glioma model: effects on tumour biomass, apoptosis and neuronal tissue histology. Prostaglandins, leukotrienes, and essential fatty acids 20021101
Comparison of the extrapancreatic action of gamma-linolenic acid and n-3 PUFAs in the high fat diet-induced insulin resistance [corrected]. Endocrine regulations 20021101
5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids. The Journal of steroid biochemistry and molecular biology 20021101
Measurement by nuclear magnetic resonance diffusion of the dimensions of the mobile lipid compartment in C6 cells. Cancer research 20021015
Differential expression of desaturases and changes in fatty acid composition during sporangiospore germination and development in Mucor rouxii. Fungal genetics and biology : FG & B 20021001
[Prevention and treatment of diabetic neuropathy]. Nihon rinsho. Japanese journal of clinical medicine 20021001
Constituents in evening primrose oil with radical scavenging, cyclooxygenase, and neutrophil elastase inhibitory activities. Journal of agricultural and food chemistry 20020925
Doctor accused of giving false information to drug trial. BMJ (Clinical research ed.) 20020921
Effects of diabetes and evening primrose oil treatment on responses of aorta, corpus cavernosum and mesenteric vasculature in rats. Life sciences 20020906
Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. Nutrition (Burbank, Los Angeles County, Calif.) 20020901
Eicosapentaenoic acid and gamma-linolenic acid induce apoptosis in HL-60 cells. The Journal of surgical research 20020901
Ayurvedic medicines. Pharmacoepidemiology and drug safety 20020901
Positional distribution of FA in TAG of enzymatically modified borage and evening primrose oils. Lipids 20020801
A direct method for regiospecific analysis of TAG using alpha-MAG. Lipids 20020801
Intravesical meglumine gamma-linolenic acid in superficial bladder cancer: an efficacy study. European urology 20020701
Gamma-linolenic acid alters the composition of mitochondrial membrane subfractions, decreases outer mitochondrial membrane binding of hexokinase and alters carnitine palmitoyltransferase I properties in the Walker 256 rat tumour. Biochimica et biophysica acta 20020613
Modification of fatty acid composition in tomato (Lycopersicon esculentum) by expression of a borage delta6-desaturase. Molecular biotechnology 20020601
gamma-Linoleic acid and ascorbic acid ameliorate the effects of experimental diabetes on electrolyte and bone homeostasis in pregnant rats. The Journal of endocrinology 20020501
High-level production of gamma-linolenic acid in Brassica juncea using a delta6 desaturase from Pythium irregulare. Plant physiology 20020501
Cloning and molecular characterization of the delta6-desaturase from two echium plant species: production of GLA by heterologous expression in yeast and tobacco. Lipids 20020401
Synergistic interaction between vinorelbine and gamma-linolenic acid in breast cancer cells. Breast cancer research and treatment 20020401
Production of gamma-linolenic acid by Cunninghamella echinulata cultivated on glucose and orange peel. Applied microbiology and biotechnology 20020301
The effects of meglumine gamma linolenic acid (MeGLA) on an organ culture model of superficial bladder cancer. Urological research 20020301
Oral administration of gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, modulates interleukin-1beta production by human monocytes. Journal of clinical immunology 20020301
Golden nail pigmentation. The Journal of dermatological treatment 20020301
Structured lipids via lipase-catalyzed incorporation of eicosapentaenoic acid into borage (Borago officinalis L.) and evening primrose (Oenothera biennis L.) oils. Journal of agricultural and food chemistry 20020130
Regulation of the rat SREBP-1c promoter in primary rat hepatocytes. Biochemical and biophysical research communications 20020111
The therapeutic effect of evening primrose oil in atopic dermatitis patients with dry scaly skin lesions is associated with the normalization of serum gamma-interferon levels. Skin pharmacology and applied skin physiology 20020101
Antitumour and pro-apoptotic actions of highly unsaturated fatty acids in glioma. Prostaglandins, leukotrienes, and essential fatty acids 20020101
Abrupt and complete occlusion of tumor-feeding vessels by gamma-linolenic acid. Nutrition (Burbank, Los Angeles County, Calif.) 20020101
Gammalinolenic acid treatment of fatigue associated with primary Sjögren's syndrome. Scandinavian journal of rheumatology 20020101
The effect of gamma-linolenic acid on plasma and membrane lipids and renal prostaglandin synthesis in older subjects. Bratislavske lekarske listy 20020101
[Synthesis of biologically active lipids by fungus Mucor lusitanicus 306D grown on media with various composition]. Prikladnaia biokhimiia i mikrobiologiia 20020101
Hypocholesterolemic effect of spirulina in patients with hyperlipidemic nephrotic syndrome. Journal of medicinal food 20020101
Dietary EPA reduces tumor load in ApcMin/+ mice by altering arachidonic acid metabolism, but conjugated linoleic acid, gamma--and alpha-linolenic acids have no effect. Advances in experimental medicine and biology 20020101
Delta-6 desaturase activity and gene expression, tissue fatty acid profile and glucose turnover rate in hereditary hypertriglyceridemic rats. Endocrine regulations 20011201
Fatty acid composition of lymphocyte membrane phospholipids in children with acute leukemia. Cancer letters 20011128
Borage oil reduction of rheumatoid arthritis activity may be mediated by increased cAMP that suppresses tumor necrosis factor-alpha. International immunopharmacology 20011101
Influence of dietary supplementation with long-chain n-3 or n-6 polyunsaturated fatty acids on blood inflammatory cell populations and functions and on plasma soluble adhesion molecules in healthy adults. Lipids 20011101
gamma-Linolenic acid and eicosapentaenoic acid induce modifications in mitochondrial metabolism, reactive oxygen species generation, lipid peroxidation and apoptosis in Walker 256 rat carcinosarcoma cells. Biochimica et biophysica acta 20011031
[Meager support for herbal therapy of rheumatoid arthritis]. Lakartidningen 20011010
Dietary mold oil rich in gamma linolenic acid increases insulin-dependent glucose utilization in isolated rat adipocytes. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20011001
The toxicities of a polyunsaturated fatty acid and a microcystin to Daphnia magna. Environmental toxicology 20011001
Dietary gamma-linolenic acid dose-dependently modifies fatty acid composition and immune parameters in rats. Prostaglandins, leukotrienes, and essential fatty acids 20011001
Benign breast pain. New approaches manage this common condition more effectively. Advance for nurse practitioners 20011001
Occurrence and characterization of oils rich in gamma-linolenic acid (III): the taxonomical value of the fatty acids in Echium (Boraginaceae). Phytochemistry 20010901
Antioxidant properties of evening primrose seed extracts. Journal of agricultural and food chemistry 20010901
2,3-Dinor-5,6-dihydro-15-F(2t)-isoprostane: a bioactive prostanoid metabolite. American journal of physiology. Regulatory, integrative and comparative physiology 20010801
The effects of treatment with alpha-lipoic acid or evening primrose oil on vascular hemostatic and lipid risk factors, blood flow, and peripheral nerve conduction in the streptozotocin-diabetic rat. Metabolism: clinical and experimental 20010801
Gammalinolenic acid, an unsaturated fatty acid with anti-inflammatory properties, blocks amplification of IL-1 beta production by human monocytes. Journal of immunology (Baltimore, Md. : 1950) 20010701
Polyunsaturated fatty acids in maternal diet, breast milk, and serum lipid fatty acids of infants in relation to atopy. Allergy 20010701
Modification of doxorubicin-induced cardiotoxicity: effect of essential fatty acids and ICRF-187 (dexrazoxane). European journal of cancer (Oxford, England : 1990) 20010701
Ethanol-induced dimorphism and lipid composition changes in Mucor fragilis CCMI 142. Letters in applied microbiology 20010701
Fat-specific satiety in humans for fat high in linoleic acid vs fat high in oleic acid. European journal of clinical nutrition 20010601
Influence of formulas with borage oil or borage oil plus fish oil on the arachidonic acid status in premature infants. Lipids 20010601
Effect of dietary GLA+/-tamoxifen on the growth, ER expression and fatty acid profile of ER positive human breast cancer xenografts. International journal of cancer 20010501
Repression of cellular anaplerosis as the hypothesized mechanism of gamma-linolenic acid-induced toxicity to tumor cells. Medical hypotheses 20010501
[Nutritional support for ARDS]. Nihon rinsho. Japanese journal of clinical medicine 20010501
Oxidative stress participates in the breakdown of neuronal phenotype in experimental diabetic neuropathy. Diabetologia 20010401
Activity of soybean lipoxygenase isoforms against esterified fatty acids indicates functional specificity. Archives of biochemistry and biophysics 20010401
The effect of low light flux and nitrogen deficiency on the chemical composition of Spirulina sp. (Arthrospira) grown on digested pig waste. Bioresource technology 20010301
Role of gamma-linolenic acid in counteracting doxorubicin-induced damage in cultured rat cardiomyocytes. Prostaglandins, leukotrienes, and essential fatty acids 20010301
Effects of diets enriched in n-6 or n-3 fatty acids on cholesterol metabolism in older rats chronically fed a cholesterol-enriched diet. Lipids 20010301
Effects of polyunsaturated fatty acids on atrophic gastritis in a Japanese population. Cancer letters 20010226
Gamma-linolenic acid biosynthesis: cryptoregiochemistry of delta6 desaturation. The Journal of organic chemistry 20010223
Trifluoromethyl-containing 3-alkoxymethyl- and 3-aryloxymethyl-2-pyridinones are potent inhibitors of HIV-1 non-nucleoside reverse transcriptase. Bioorganic & medicinal chemistry letters 20010212
gamma-Linolenic acid production by solid-state fermentation of Mucorales strains on cereals. Bioresource technology 20010201
Biochemical effects of supplemented long-chain polyunsaturated fatty acids in hyperphenylalaninemia. Prostaglandins, leukotrienes, and essential fatty acids 20010201
Effects of gamma-linolenic acid and oleic acid on paclitaxel cytotoxicity in human breast cancer cells. European journal of cancer (Oxford, England : 1990) 20010201
[Are there effective dietary recommendations for patients with rheumatoid arthritis?]. Zeitschrift fur Rheumatologie 20010201
Effect of conjugated linoleic acid on fungal delta6-desaturase activity in a transformed yeast system. Lipids 20010201
Interactions of dietary fats and proteins on fatty acid composition of immune cells and LTB4 production by peritoneal exudate cells of rats. Bioscience, biotechnology, and biochemistry 20010201
Stereotactic radiosurgery XII. Large AVM and the failure of the radiation response modifier gamma linolenic acid to improve the therapeutic ratio. British journal of neurosurgery 20010201
Modifications in mitochondrial metabolism and ultrastructure and their relationship to tumour growth inhibition by gamma-linolenic acid. Molecular and cellular biochemistry 20010201
The effect of gamma-linolenic acid-alpha-lipoic acid on functional deficits in the peripheral and central nervous system of streptozotocin-diabetic rats. Journal of the neurological sciences 20010101
Gamma-linolenic acid and tocopherol contents in the seed oil of 47 accessions from several Ribes species. Journal of agricultural and food chemistry 20010101
Cataract development in diabetic sand rats treated with alpha-lipoic acid and its gamma-linolenic acid conjugate. Diabetes/metabolism research and reviews 20010101
Herbal therapy for treating rheumatoid arthritis. The Cochrane database of systematic reviews 20010101
Potential of evening primrose, borage, black currant, and fungal oils in human health. Annals of nutrition & metabolism 20010101
Peroxisome proliferator-activated receptor- gamma expression in human malignant and normal brain, breast and prostate-derived cells. Prostaglandins, leukotrienes, and essential fatty acids 20010101
Gamma-linolenic acid induces apoptosis in B-chronic lymphocytic leukaemia cells in vitro. Leukemia & lymphoma 20010101
NMR and isotope ratio mass spectrometry studies of in vivo uptake and metabolism of polyunsaturates by the developing rat brain. Journal of molecular neuroscience : MN 20010101
[Effect of gamma-linolenic acid on microsomal oxidation in the rat liver following gamma-irradiation]. Eksperimental'naia i klinicheskaia farmakologiia 20010101
Corpus cavernosum dysfunction in diabetic rats: effects of combined alpha-lipoic acid and gamma-linolenic acid treatment. Diabetes/metabolism research and reviews 20010101
Fatty acid composition of Chlorella and Spirulina microalgae species. Journal of AOAC International 20010101
Vaccenic acid feeding increases tissue levels of conjugated linoleic acid and suppresses development of premalignant lesions in rat mammary gland. Nutrition and cancer 20010101
Identification of the major intestinal fatty acid transport protein. Molecular cell 19990901
Evidence for direct binding of fatty acids and eicosanoids to human peroxisome proliferators-activated receptor alpha. Biochemical and biophysical research communications 19990714
Characterization of arachidonic acid-induced apoptosis. Cell biochemistry and biophysics 19990101
Modulation in vitro of human natural cytotoxicity, lymphocyte proliferative response to mitogens and cytokine production by essential fatty acids. Immunology 19971001
Bimoclomol (BRLP-42) ameliorates peripheral neuropathy in streptozotocin-induced diabetic rats. Brain research bulletin 19970101
Synergistic effects of fish oil diet and dimethylthiourea in acute adriamycin nephrosis. The American journal of the medical sciences 19941101
Treatment of lithium-induced tremor and familial essential tremor with essential fatty acids. Progress in lipid research 19810101
Properties