Home Other Building Blocks Fluocinolone acetonide

Fluocinolone acetonide

CAS No.:
67-73-2
Catalog Number:
AG0034XJ
Molecular Formula:
C24H30F2O6
Molecular Weight:
452.4882
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
98%
In Stock USA
United States
$69
- +
5g
98%
In Stock USA
United States
$244
- +
10g
98%
In Stock USA
United States
$437
- +
25g
98%
In Stock USA
United States
$781
- +
Product Description
Catalog Number:
AG0034XJ
Chemical Name:
Fluocinolone acetonide
CAS Number:
67-73-2
Molecular Formula:
C24H30F2O6
Molecular Weight:
452.4882
MDL Number:
MFCD00010525
IUPAC Name:
(1S,2S,4R,8S,9S,11S,12R,13S,19S)-12,19-difluoro-11-hydroxy-8-(2-hydroxyacetyl)-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-14,17-dien-16-one
InChI:
InChI=1S/C24H30F2O6/c1-20(2)31-19-9-13-14-8-16(25)15-7-12(28)5-6-21(15,3)23(14,26)17(29)10-22(13,4)24(19,32-20)18(30)11-27/h5-7,13-14,16-17,19,27,29H,8-11H2,1-4H3/t13-,14-,16-,17-,19+,21-,22-,23-,24+/m0/s1
InChI Key:
FEBLZLNTKCEFIT-VSXGLTOVSA-N
SMILES:
OCC(=O)[C@@]12OC(O[C@@H]1C[C@@H]1[C@]2(C)C[C@H](O)[C@]2([C@H]1C[C@@H](C1=CC(=O)C=C[C@]21C)F)F)(C)C
EC Number:
200-668-5
UNII:
0CD5FD6S2M
NSC Number:
92339
Properties
Complexity:
960  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Defined Bond Stereocenter Count:
0
Exact Mass:
452.201g/mol
Formal Charge:
0
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
452.495g/mol
Monoisotopic Mass:
452.201g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
93.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.5  
Literature
Title Journal
Safety and efficacy of fluocinolone acetonide intravitreal implant (0.59 mg) in birdshot retinochoroidopathy. Retina (Philadelphia, Pa.) 20141101
Sustained delivery fluocinolone acetonide vitreous inserts provide benefit for at least 3 years in patients with diabetic macular edema. Ophthalmology 20121001
Corticosteroid use for diabetic macular edema: old fad or new trend? Current diabetes reports 20120801
Intraocular corticosteroids for posterior segment disease: 2012 update. Expert opinion on pharmacotherapy 20120801
Trends in older adult psoriasis outpatient health care practices in the United States. Journal of drugs in dermatology : JDD 20120801
Nebulized corticosteroids in asthma and COPD. An Italian appraisal. Respiratory care 20120701
Combined posterior chamber intraocular lens, vitrectomy, Retisert, and pars plana tube in noninfectious uveitis. Archives of ophthalmology (Chicago, Ill. : 1960) 20120701
[Clinical signs of Cushing's syndrome after long-term local application of steroid in the oral cavity]. Ugeskrift for laeger 20120625
Preventing melasma recurrence: prescribing a maintenance regimen with an effective triple combination cream based on long-standing clinical severity. Journal of the European Academy of Dermatology and Venereology : JEADV 20120501
[The diabetic macular edema--new possibilities of the treatment]. Ceska a slovenska oftalmologie : casopis Ceske oftalmologicke spolecnosti a Slovenske oftalmologicke spolecnosti 20120501
Late (≥ 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants. The Cochrane database of systematic reviews 20120418
Spontaneous resolution of intravitreal steroid-induced bilateral cytomegalovirus retinitis. Korean journal of ophthalmology : KJO 20120401
Treatment of intractable posterior uveitis in pediatric patients with the fluocinolone acetonide intravitreal implant (Retisert). Retina (Philadelphia, Pa.) 20120301
Associations among visual acuity and vision- and health-related quality of life among patients in the multicenter uveitis steroid treatment trial. Investigative ophthalmology & visual science 20120301
Incorporation of anti-inflammatory agent into calcium hydroxide pulp capping material: an in vitro study of physical and mechanical properties. Dental materials journal 20120203
Topical hypopigmenting agents for pigmentary disorders and their mechanisms of action. Annals of dermatology 20120201
A PAMPA assay as fast predictive model of passive human skin permeability of new synthesized corticosteroid C-21 esters. Molecules (Basel, Switzerland) 20120105
Prospective study of a fluocinolone acetonide implant for chronic macular edema from central retinal vein occlusion: thirty-six-month results. Ophthalmology 20120101
Dendrimer-based targeted intravitreal therapy for sustained attenuation of neuroinflammation in retinal degeneration. Biomaterials 20120101
Scleral thickness in human eyes. PloS one 20120101
Post-cataract outcomes in patients with noninfectious posterior uveitis treated with the fluocinolone acetonide intravitreal implant. Clinical ophthalmology (Auckland, N.Z.) 20120101
Update on sympathetic ophthalmia. Middle East African journal of ophthalmology 20120101
EMBO Retinoids 2011: Mechanisms, biology and pathology of signaling by retinoic acid and retinoic acid receptors. Nuclear receptor signaling 20120101
Emerging pharmacotherapies for diabetic macular edema. Experimental diabetes research 20120101
Recurrent acute rhinosinusitis: a single blind clinical study of N-acetylcysteine vs ambroxol associated to corticosteroid therapy. International journal of immunopathology and pharmacology 20120101
Corticosteroid intravitreal implants. Developments in ophthalmology 20120101
Win percentage: a novel measure for assessing the suitability of machine classifiers for biological problems. BMC bioinformatics 20120101
Long-term results of oral valganciclovir for treatment of anterior segment inflammation secondary to cytomegalovirus infection. Clinical ophthalmology (Auckland, N.Z.) 20120101
Triple combination and glycolic peels in post-acne hyperpigmentation. Journal of cutaneous and aesthetic surgery 20120101
Cytomegalovirus retinitis after central retinal vein occlusion in a patient on systemic immunosuppression: does venooclusive disease predispose to cytomegalovirus retinitis in patients already at risk? Clinical ophthalmology (Auckland, N.Z.) 20120101
Necrotizing keratitis after laser refractive surgery in patients with inactive inflammatory bowel disease. Case reports in ophthalmology 20120101
Oral lichen planus as a preneoplastic inflammatory model. Journal of biomedicine & biotechnology 20120101
Intravitreal devices for the treatment of vitreous inflammation. Mediators of inflammation 20120101
Identifying a clinically meaningful threshold for change in uveitic macular edema evaluated by optical coherence tomography. American journal of ophthalmology 20111201
Challenges in the design and implementation of the Multicenter Uveitis Steroid Treatment (MUST) Trial--lessons for comparative effectiveness trials. Clinical trials (London, England) 20111201
Emerging drugs for diabetic retinopathy. Expert opinion on emerging drugs 20111201
Presumed necrotizing viral retinitis after intravitreal triamcinolone injection: case report. Korean journal of ophthalmology : KJO 20111201
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
Pars plana vitrectomy, fluocinolone acetonide implantation, and silicone oil infusion for the treatment of chronic, refractory uveitic hypotony. American journal of ophthalmology 20111101
Review and update of intraocular therapy in noninfectious uveitis. Current opinion in ophthalmology 20111101
Antitumor effect of non-steroid glucocorticoid receptor ligand CpdA on leukemia cell lines CEM and K562. Biochemistry. Biokhimiia 20111101
Combined use of algorithms for peak picking, peak tracking and retention modelling to optimize the chromatographic conditions for liquid chromatography-mass spectrometry analysis of fluocinolone acetonide and its degradation products. Analytica chimica acta 20111017
Intraocular pressure outcome of patients with fluocinolone acetonide intravitreal implant for noninfectious uveitis. Ophthalmology 20111001
Assessment and management of chronic otitis externa. Current opinion in otolaryngology & head and neck surgery 20111001
Randomized comparison of systemic anti-inflammatory therapy versus fluocinolone acetonide implant for intermediate, posterior, and panuveitis: the multicenter uveitis steroid treatment trial. Ophthalmology 20111001
Hyalinization of the pyloric stomach in CD-1 mice following oral (dietary) administration of the corticosteroid agonists mometasone furoate, budesonide, and flunisolide. Toxicologic pathology 20111001
Linear growth and bone maturation are unaffected by 1 year of therapy with inhaled flunisolide hydrofluoroalkane in prepubescent children with mild persistent asthma: a randomized, double-blind, placebo-controlled trial. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20111001
Sustained release intraocular drug delivery devices for treatment of uveitis. Journal of ophthalmic & vision research 20111001
Melasma treatment with pulsed-dye laser and triple combination cream: a prospective, randomized, single-blind, split-face study. Archives of dermatology 20110901
Validation of a photographic vitreous haze grading technique for clinical trials in uveitis. American journal of ophthalmology 20110801
Morphologic assessment for glaucoma in the Multicenter Uveitis Steroid Treatment (MUST) trial. Ocular immunology and inflammation 20110801
Cytomegalovirus endotheliitis after fluocinolone acetonide (Retisert) implant in a patient with Behçet uveitis. Ocular immunology and inflammation 20110801
Fluocinolone acetonide intravitreal implant for diabetic macular edema: a 3-year multicenter, randomized, controlled clinical trial. Ophthalmology 20110801
Therapeutic Index (TIX) for intranasal corticosteroids in the treatment of allergic rhinitis. Rhinology 20110801
Treatment outcome of Paederus dermatitis due to rove beetles (Coleoptera: Staphylinidae) on guinea pigs. Tropical biomedicine 20110801
Sustained-release intravitreal liquid drug delivery using triamcinolone acetonide for cystoid macular edema in retinal vein occlusion. Ophthalmology 20110701
Trabecular meshwork and lens partitioning of corticosteroids: implications for elevated intraocular pressure and cataracts. Archives of ophthalmology (Chicago, Ill. : 1960) 20110701
Fluocinolone acetonide implant (Retisert) for chronic cystoid macular edema in two patients with AIDS and a history of cytomegalovirus retinitis. Ocular immunology and inflammation 20110601
A functional, nonfunctioning Retisert implant. Ocular immunology and inflammation 20110601
Use of a high infusion rate to prevent posterior dislocation of fluocinolone acetonide implant during surgical removal. Ocular immunology and inflammation 20110601
Activities of aldo-keto reductase 1 enzymes on two inhaled corticosteroids: implications for the pharmacological effects of inhaled corticosteroids. Chemico-biological interactions 20110530
Influence of drug solubility and lipophilicity on transscleral retinal delivery of six corticosteroids. Drug metabolism and disposition: the biological fate of chemicals 20110501
Dexamethasone for ocular inflammation. Expert opinion on pharmacotherapy 20110501
Photoactivation of corticosteroids in UVB-exposed skin. Journal of photochemistry and photobiology. B, Biology 20110404
Long-term benefit of sustained-delivery fluocinolone acetonide vitreous inserts for diabetic macular edema. Ophthalmology 20110401
Investigation of solvolysis kinetics of new synthesized fluocinolone acetonide C-21 esters--an in vitro model for prodrug activation. Molecules (Basel, Switzerland) 20110323
Fluocinolone acetonide implantable device for diabetic retinopathy. Current pharmaceutical biotechnology 20110301
Triple combination and glycolic acid peels in melasma in Indian patients. Journal of cosmetic dermatology 20110301
[Intravitreal implants: drug carriers and carriers of hope?]. Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft 20110301
Herpetic necrotizing retinitis following flucinolone acetonide intravitreal implant. Ocular immunology and inflammation 20110201
Effect of fluocinolone acetonide on human dental pulp cells: cytotoxicity, proliferation, and extracellular matrix formation. Journal of endodontics 20110201
Sequential treatment with triple combination cream and intense pulsed light is more efficacious than sequential treatment with an inactive (control) cream and intense pulsed light in patients with moderate to severe melasma. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20110201
Low-fluence Q-switched neodymium-doped yttrium aluminum garnet laser for melasma with pre- or post-treatment triple combination cream. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20110101
Intranasal flunisolide treatment in patients with non-allergic rhinitis. International journal of immunopathology and pharmacology 20110101
Inflammatory glaucoma. Oman journal of ophthalmology 20110101
Biocompatibility and biodegradation studies of subconjunctival implants in rabbit eyes. PloS one 20110101
Alopecia: evaluation and treatment. Clinical, cosmetic and investigational dermatology 20110101
Alopecia areata: a new treatment plan. Clinical, cosmetic and investigational dermatology 20110101
A new paleozoic Symmoriiformes (Chondrichthyes) from the late Carboniferous of Kansas (USA) and cladistic analysis of early chondrichthyans. PloS one 20110101
Dexamethasone intravitreal implant for the treatment of noninfectious uveitis. Clinical ophthalmology (Auckland, N.Z.) 20110101
Atopic dermatitis. Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20110101
Nanotechnology and nanotoxicology in retinopathy. International journal of molecular sciences 20110101
A study of pathogenesis of acanthosis nigricans and its clinical implications. Indian journal of dermatology 20110101
Combination therapies in ophthalmology: implications for intravitreal delivery. Journal of ophthalmic & vision research 20110101
'For export only' medicines come back to Europe: a RP-LC method for the screening of six glucocorticoids in illegal and counterfeit anti-inflammatory and lightening creams. Journal of pharmaceutical and biomedical analysis 20101010
Cost-effectiveness of a hydroquinone/tretinoin/fluocinolone acetonide cream combination in treating melasma in the United States. The Journal of dermatological treatment 20100901
Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period. European journal of clinical pharmacology 20100901
Recent advances in ophthalmic drug delivery. Therapeutic delivery 20100901
Intravitreous delivery of the corticosteroid fluocinolone acetonide attenuates retinal degeneration in S334ter-4 rats. Investigative ophthalmology & visual science 20100801
Scleral thickness following fluocinolone acetonide implant (Retisert). Ocular immunology and inflammation 20100801
Interventions for melasma. The Cochrane database of systematic reviews 20100707
The effect of a preoperative subconjuntival injection of dexamethasone on blood-retinal barrier breakdown following scleral buckling retinal detachment surgery: a prospective randomized placebo-controlled double blind clinical trial. Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20100701
Sustained ocular delivery of fluocinolone acetonide by an intravitreal insert. Ophthalmology 20100701
Drug-target interaction prediction from chemical, genomic and pharmacological data in an integrated framework. Bioinformatics (Oxford, England) 20100615
Low-fluence Q-switched neodymium-doped yttrium aluminum garnet laser for melasma with pre- or post-treatment triple combination cream. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20100601
Continuous therapy followed by a maintenance therapy regimen with a triple combination cream for melasma. Journal of the American Academy of Dermatology 20100601
The clinical utility of a hand-held computerized optical imaging system at assessing skin discoloration. Journal of cosmetic dermatology 20100601
Combined fluocinolone acetonide intravitreal insertion and glaucoma drainage device placement for chronic uveitis and glaucoma. American journal of ophthalmology 20100501
Proof of concept for combined insertion of fluocinolone acetonide and glaucoma drainage implants for eyes with uveitis and glaucoma. American journal of ophthalmology 20100501
Modulation by flunisolide of tumor necrosis factor-alpha-induced stimulation of airway epithelial cell activities related to eosinophil inflammation. The Journal of asthma : official journal of the Association for the Care of Asthma 20100501
Use of ozone-depleting substances; removal of essential-use designation (flunisolide, etc.). Final rule. Federal register 20100414
The multicenter uveitis steroid treatment trial: rationale, design, and baseline characteristics. American journal of ophthalmology 20100401
Evaluation of an intravitreal fluocinolone acetonide implant versus standard systemic therapy in noninfectious posterior uveitis. Ophthalmology 20100301
An application of second-order UV-derivative spectrophotometry for study of solvolysis of a novel fluocinolone acetonide ester. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100201
Biodegradable intraocular therapies for retinal disorders: progress to date. Drugs & aging 20100201
Cytomegalovirus endotheliitis following fluocinolone acetonide (Retisert) implant. Eye (London, England) 20100101
Juvenile bullous pemphigoid: the presentation and follow-up of six cases. Journal of the European Academy of Dermatology and Venereology : JEADV 20100101
Current approach in the diagnosis and management of posterior uveitis. Indian journal of ophthalmology 20100101
The evolving role of therapeutic shampoos for targeting symptoms of inflammatory scalp disorders. Journal of drugs in dermatology : JDD 20100101
Oral lichenoid drug reaction associated with antihypertensive and hypoglycemic drugs. Journal of drugs in dermatology : JDD 20100101
Optimal management of cytomegalovirus retinitis in patients with AIDS. Clinical ophthalmology (Auckland, N.Z.) 20100101
Management of alopecia areata. BMJ (Clinical research ed.) 20100101
Antiretroviral Drug-Associated Oral Lichenoid Reaction in HIV Patient: A Case Report. International journal of dentistry 20100101
Differentiating intraocular glucocorticoids. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20100101
New developments in corticosteroid therapy for uveitis. Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20100101
Drug delivery options for the treatment of ocular inflammation. Seminars in ophthalmology 20100101
Treatment of noninfectious posterior uveitis with dexamethasone intravitreal implant. Clinical ophthalmology (Auckland, N.Z.) 20100101
Levels of salivary IFN-gamma, TNF-alfa, and TNF receptor-2 as prognostic markers in (erosive) oral lichen planus. Mediators of inflammation 20100101
Mometasone-based triple combination therapy in melasma: is it really safe? Indian journal of dermatology 20100101
Desipramine inhibits the growth of a mouse skin squamous cell carcinoma cell line and affects glucocorticoid receptor-mediated transcription. Molecular carcinogenesis 20091201
A histological examination for skin atrophy after 6 months of treatment with fluocinolone acetonide 0.01%, hydroquinone 4%, and tretinoin 0.05% cream. The American Journal of dermatopathology 20091201
The role of spirituality healing with perceptions of the medical encounter among Latinos. Journal of general internal medicine 20091101
Photoreceptor neuroprotection in RCS rats via low-dose intravitreal sustained-delivery of fluocinolone acetonide. Investigative ophthalmology & visual science 20091001
Expression of IFN-gamma before and after treatment of oral lichen planus with 0.1% fluocinolone acetonide in orabase. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20091001
Hyperpigmentation: old problem, new therapies. Journal of drugs in dermatology : JDD 20090901
Management of fluocinolone implant dissociation during implant exchange. Archives of ophthalmology (Chicago, Ill. : 1960) 20090901
Endogenous tenascin-C enhances glioblastoma invasion with reactive change of surrounding brain tissue. Cancer science 20090801
Melasma in Latin America: options for therapy and treatment algorithm. Journal of the European Academy of Dermatology and Venereology : JEADV 20090701
The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids. The Journal of allergy and clinical immunology 20090601
Effect of phosphodiesterase antagonists on glucocorticoid mediated growth inhibition in murine skin cell lines. European journal of pharmacology 20090521
Improvement of idiopathic acanthosis nigricans with a triple combination depigmenting cream. Journal of the European Academy of Dermatology and Venereology : JEADV 20090401
Targetoid pattern of hair regrowth in alopecia areata: a case report. Clinical and experimental dermatology 20090401
Fluocinolone inhibits VEGF expression via glucocorticoid receptor in human retinal pigment epithelial (ARPE-19) cells and TNF-alpha-induced angiogenesis in chick chorioallantoic membrane (CAM). Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20090401
Lymph node assessment: issues in pathology. Journal of surgical oncology 20090315
Promotion of mouse two-stage skin carcinogenesis by diacylglycerol-rich edible oil. Cancer letters 20090308
Management of sympathetic ophthalmia with the fluocinolone acetonide implant. Ophthalmology 20090301
Prevalence and management of elevated intraocular pressure after placement of an intravitreal sustained-release steroid implant. Current opinion in ophthalmology 20090301
Intravitreal inserts of steroids to treat diabetic macular edema. Current diabetes reviews 20090201
Uveitis treated with fluocinolone acetonide implants. Archives of ophthalmology (Chicago, Ill. : 1960) 20090101
Validation of a solid-phase extraction and ultra-performance liquid chromatographic tandem mass spectrometric method for the detection of 16 glucocorticoids in pig tissues. Journal of AOAC International 20090101
The role of topical retinoids in the treatment of pigmentary disorders: an evidence-based review. American journal of clinical dermatology 20090101
Primary treatment of diabetic macular edema. Clinical interventions in aging 20090101
High-dose inhaled flunisolide versus budesonide in the treatment of acute asthma exacerbations in preschool-age children. International journal of immunopathology and pharmacology 20090101
Overall and cancer related mortality among patients with ocular inflammation treated with immunosuppressive drugs: retrospective cohort study. BMJ (Clinical research ed.) 20090101
Prevention of surgery in children with adenoidal hypertrophy treated with intranasal flunisolide: a 12-month follow-up. Journal of biological regulators and homeostatic agents 20090101
Fluocinolone acetonide 0.01% in peanut oil: safety and efficacy data in the treatment of childhood atopic dermatitis in infants as young as 3 months of age. Pediatric dermatology 20090101
Glucocorticoids with different chemical structures but similar glucocorticoid receptor potency regulate subsets of common and unique genes in human trabecular meshwork cells. BMC medical genomics 20090101
Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles. PloS one 20090101
Fluocinolone acetonide intravitreal implants in Vogt-Koyanagi-Harada disease. Ocular immunology and inflammation 20090101
Triple combination of hydroquinone, tretinoin and mometasone furoate with glycolic acid peels in melasma. Indian journal of dermatology 20090101
Topical treatment of melasma. Indian journal of dermatology 20090101
Etiology and treatment of the inflammatory causes of cystoid macular edema. Journal of inflammation research 20090101
Cystoid macular edema. Clinical ophthalmology (Auckland, N.Z.) 20081201
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry 20081113
Successful treatment of moderate to severe melasma with triple-combination cream and glycolic acid peels: a pilot study. Cutis 20081101
Chronic cutaneous lupus erythematosus in vitiligo. Dermatology online journal 20081015
Outcome of fluocinolone acetonide implant (Retisert) reimplantation for chronic noninfectious posterior uveitis. Retina (Philadelphia, Pa.) 20081001
Combined fluocinolone acetonide intraocular delivery system insertion, phacoemulsification, and intraocular lens implantation for severe uveitis. American journal of ophthalmology 20081001
Immune system and inflammation. Indian journal of pharmacology 20081001
A randomized controlled trial of the efficacy and safety of a fixed triple combination (fluocinolone acetonide 0.01%, hydroquinone 4%, tretinoin 0.05%) compared with hydroquinone 4% cream in Asian patients with moderate to severe melasma. The British journal of dermatology 20080901
Iluvien: a new sustained delivery technology for posterior eye disease. Expert opinion on drug delivery 20080901
Treatment of posterior uveitis with a fluocinolone acetonide implant: three-year clinical trial results. Archives of ophthalmology (Chicago, Ill. : 1960) 20080901
Fluocinolone acetonide for the treatment of uveitis: weighing the balance between local and systemic immunosuppression. Archives of ophthalmology (Chicago, Ill. : 1960) 20080901
Fluocinolone acetonide sustained drug delivery device for chronic central retinal vein occlusion: 12-month results. American journal of ophthalmology 20080801
Cytomegalovirus retinitis after intravitreous triamcinolone injection in a patient with central retinal vein occlusion. Korean journal of ophthalmology : KJO 20080601
Current and future approaches in the prevention and treatment of diabetic retinopathy. Clinical ophthalmology (Auckland, N.Z.) 20080601
Efalizumab: results of a 3-year continuous dosing study for the long-term control of psoriasis. The British journal of dermatology 20080501
Update on treatments for diabetic macular edema. Current opinion in ophthalmology 20080501
Nebulisation of corticosteroid suspensions and solutions with a beta(2) agonist. The Journal of pharmacy and pharmacology 20080501
Partitioning of anti-inflammatory steroid drugs into phosphatidylcholine and phosphatidylcholine-cholesterol small unilamellar vesicles as studied by second-derivative spectrophotometry. Chemical & pharmaceutical bulletin 20080501
Reimplantation of a fluocinolone acetonide sustained drug delivery implant for chronic uveitis. American journal of ophthalmology 20080401
Subcutaneous emphysema caused by cryotherapy application over a corticosteroid-induced atrophic skin. Journal of the European Academy of Dermatology and Venereology : JEADV 20080401
Lichenoid and other clinical presentations of atopic dermatitis in an inner city practice. Journal of the American Academy of Dermatology 20080301
Intravitreal steroids for macular edema in diabetes. The Cochrane database of systematic reviews 20080123
Diabetic retinopathy: an update. Indian journal of ophthalmology 20080101
Treatment of serpiginous choroiditis with intravitreous fluocinolone acetonide implant. Ocular immunology and inflammation 20080101
PSivida corporation. Arzneimittel-Forschung 20080101
Intravitreal steroid slow-release device replacing repeated intravitreal triamcinolone injections for sympathetic ophthalmia. European journal of ophthalmology 20080101
Use of intravitreal triamcinolone in the treatment of macular edema related to retinal vein occlusion. The open ophthalmology journal 20080101
Injectable, in situ forming poly(propylene fumarate)-based ocular drug delivery systems. Journal of biomedical materials research. Part A 20071201
Epithelial cells in the hair follicle bulge do not contribute to epidermal regeneration after glucocorticoid-induced cutaneous atrophy. The Journal of investigative dermatology 20071201
Stem cells in the hair follicle and interfollicular epidermis of mice following topical application of fluocinolone acetonide. The Journal of investigative dermatology 20071201
An efficacy study of 3 commercially available hydroquinone 4% treatments for melasma. Cutis 20071201
Pharmacologic therapies for diabetic retinopathy and diabetic macular edema. Clinical ophthalmology (Auckland, N.Z.) 20071201
Intraocular pressure in patients with uveitis treated with fluocinolone acetonide implants. Archives of ophthalmology (Chicago, Ill. : 1960) 20071101
Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects. Respiratory medicine 20070701
Vitreous band formation and the sustained-release, intravitreal fluocinolone (Retisert) implant. Archives of ophthalmology (Chicago, Ill. : 1960) 20070601
Drug delivery methods for posterior segment disease. Current opinion in ophthalmology 20070501
Hypertrichosis as a side effect of inhaled steroids in children. Pediatric pulmonology 20070401
Retisert: is the new advance in treatment of uveitis a good one? The Annals of pharmacotherapy 20070301
A comparison of triple combination cream and hydroquinone 4% cream for the treatment of moderate to severe facial melasma. Journal of cosmetic dermatology 20070301
Fluocinolone acetonide intravitreal sustained release device--a new addition to the armamentarium of uveitic management. International journal of nanomedicine 20070301
Cytomegalovirus retinitis after fluocinolone acetonide (Retisert) implant. American journal of ophthalmology 20070201
Cost-effectiveness of a fixed combination of hydroquinone/tretinoin/fluocinolone cream compared with hydroquinone alone in the treatment of melasma. Journal of drugs in dermatology : JDD 20070201
Emerging therapies for the treatment of neovascular age-related macular degeneration and diabetic macular edema. BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20070101
Pharmacotherapies for diabetic retinopathy: present and future. Experimental diabetes research 20070101
Compressor/nebulizers differences in the nebulization of corticosteroids. The CODE study (Corticosteroids and Devices Efficiency). European review for medical and pharmacological sciences 20070101
A reappraisal of the clinical efficacy of nebulized flunisolide in pediatric asthma: the Italian experience. Allergy and asthma proceedings 20070101
Intranasal flunisolide treatment in children with adenoidal hypertrophy. International journal of immunopathology and pharmacology 20070101
Corticosteroid therapy in the treatment of pediatric patients with atopic dermatitis. GMS health technology assessment 20070101
Intravitreal steroids in the management of macular oedema. Acta ophthalmologica Scandinavica 20061201
Ethnic considerations in the treatment of Hispanic and Latin-American patients with hyperpigmentation. The British journal of dermatology 20061201
Validation of a melasma quality of life questionnaire for Brazilian Portuguese language: the MelasQoL-BP study and improvement of QoL of melasma patients after triple combination therapy. The British journal of dermatology 20061201
[New drugs in the treatment of noninfectious uveitis]. Archivos de la Sociedad Espanola de Oftalmologia 20061201
Topical glucocorticosteroids in rhinitis: clinical aspects. Acta oto-laryngologica 20061001
Treating chronic noninfectious posterior segment uveitis: the impact of cumulative damage. Proceedings of an expert panel roundtable discussion. Retina (Philadelphia, Pa.) 20061001
Long-term release of fluocinolone acetonide using biodegradable fumarate-based polymers. Journal of controlled release : official journal of the Controlled Release Society 20060828
Postinflammatory hyperpigmentation: evolving combination treatment strategies. Cutis 20060801
Efficacy of low-release-rate fluocinolone acetonide intravitreal implants to treat experimental uveitis. Archives of ophthalmology (Chicago, Ill. : 1960) 20060701
Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: thirty-four-week results of a multicenter randomized clinical study. Ophthalmology 20060601
Dark brown scaly plaques on face and ears. The Journal of family practice 20060601
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Long-term continuous efalizumab therapy in patients with moderate to severe chronic plaque psoriasis: updated results from an ongoing trial. Journal of the American Academy of Dermatology 20060401
Once-daily intranasal corticosteroids for allergic rhinitis. Examining Treatment issues. Advance for nurse practitioners 20060401
Expression of TNF-alpha in oral lichen planus treated with fluocinolone acetonide 0.1%. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20060301
Community-based trial of a triple-combination agent for the treatment of facial melasma. Cutis 20060301
Efficacy of nebulized flunisolide combined with salbutamol and ipratropium bromide in stable patients with moderate-to-severe chronic obstructive pulmonary disease. Respiration; international review of thoracic diseases 20060101
Inhaled flunisolide suppresses the hypothalamic-pituitary-adrenocortical axis, but has minimal systemic immune effects in healthy cats. Journal of veterinary internal medicine 20060101
A comprehensive review of the long-term and short-term treatment of melasma with a triple combination cream. American journal of clinical dermatology 20060101
Flunisolide decreases exhaled nitric oxide and nitrotyrosine levels in asthmatic children. Mediators of inflammation 20060101
Nebulized drug admixtures: effect on aerosol characteristics and albuterol output. Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20060101
Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: effect of hydrofluoroalkane-flunisolide. The Journal of allergy and clinical immunology 20051101
Retisert (Bausch & Lomb/Control Delivery Systems). Current opinion in investigational drugs (London, England : 2000) 20051101
Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis. Ophthalmology 20050701
The nitrosterols--a step forward from the steroid anti-inflammatory drugs? Expert opinion on investigational drugs 20050701
Effects of drug treatment on inflammation and hyperreactivity of airways and on immune variables in cats with experimentally induced asthma. American journal of veterinary research 20050701
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20050601
The safety profile of long-term, high-dose intraocular corticosteroid delivery. American journal of ophthalmology 20050301
Steroids for choroidal neovascularization. American journal of ophthalmology 20050301
Photochemistry and phototoxicity of fluocinolone 16,17-acetonide. Photochemistry and photobiology 20050101
Comparison of the analysis of corticosteroids using different techniques. Analytical and bioanalytical chemistry 20050101
Hydroquinone 4%, tretinoin 0.05%, fluocinolone acetonide 0.01%: a safe and efficacious 12-month treatment for melasma. Cutis 20050101
Fluocinolone acetonide ophthalmic--Bausch & Lomb: fluocinolone acetonide Envision TD implant. Drugs in R&D 20050101
A large 12-month extension study of an 8-week trial to evaluate the safety and efficacy of triple combination (TC) cream in melasma patients previously treated with TC cream or one of its dyads. Journal of drugs in dermatology : JDD 20050101
Fluocinolone acetonide topical oil for scalp psoriasis. The Journal of dermatological treatment 20041201
Enhanced anti-inflammatory potency of a nitric oxide-releasing derivative of flunisolide: role of nuclear factor-kappaB. The Journal of pharmacology and experimental therapeutics 20040901
In vitro effects of flunisolide on MMP-9, TIMP-1, fibronectin, TGF-beta1 release and apoptosis in sputum cells freshly isolated from mild to moderate asthmatics. Allergy 20040901
Ocular pharmacokinetics of fluocinolone acetonide after Retisert intravitreal implantation in rabbits over a 1-year period. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040601
Treatment with inhaled flunisolide. Chest 20040501
Flunisolide HFA for the treatment of asthma: an old friend reformulated. Expert opinion on pharmacotherapy 20040501
A comparative study of punch grafting followed by topical corticosteroid versus punch grafting followed by PUVA therapy in stable vitiligo. Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] 20040101
Rationale for the use of topical corticosteroids in melasma. Journal of drugs in dermatology : JDD 20040101
Improved quality of life with effective treatment of facial melasma: the pigment trial. Journal of drugs in dermatology : JDD 20040101
Utilizing combination therapy to optimize melasma outcomes. Journal of drugs in dermatology : JDD 20040101
Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses. Proceedings of the American Thoracic Society 20040101
Common hyperpigmentation disorders in adults: Part II. Melanoma, seborrheic keratoses, acanthosis nigricans, melasma, diabetic dermopathy, tinea versicolor, and postinflammatory hyperpigmentation. American family physician 20031115
A randomized controlled trial of inhaled flunisolide in the management of acute asthma in children. Chest 20030901
Effect of topical nasal corticosteroids on patients with chronic fatigue syndrome and rhinitis. The Journal of the American Osteopathic Association 20030901
Clinical evaluation in treatment of oral lichen planus with topical fluocinolone acetonide: a 2-year follow-up. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20030701
Effect of HFA-flunisolide on peripheral lung inflammation in asthma. The Journal of allergy and clinical immunology 20030701
Efficacy and safety of a new triple-combination agent for the treatment of facial melasma. Cutis 20030701
Triple inhaled drug protocol for the treatment of acute severe asthma. Chest 20030601
Recurrent oral ulceration. SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging 20030601
Fluocinolone acetonide 0.01% in peanut oil: therapy for childhood atopic dermatitis, even in patients who are peanut sensitive. Journal of the American Academy of Dermatology 20030401
Evaluation of efficacy and safety of flunisolide hydrofluoroalkane for the treatment of asthma. Clinical therapeutics 20030301
Small airway asthma therapy, challenges, and the future. Postgraduate medicine 20030201
A curious keloid of the penis. Acta dermato-venereologica 20030101
Nasal cellularity in 183 unselected schoolchildren aged 9 to 11 years. Pediatrics 20021201
Hematologic abnormalities in recurrent oral ulceration. The Southeast Asian journal of tropical medicine and public health 20021201
Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021101
Comparison of high-dose inhaled flunisolide to systemic corticosteroids in severe adult asthma. Chest 20021001
Supercritical fluids crystallization of budesonide and flunisolide. Pharmaceutical research 20021001
Deciphering the phosphorylation 'code' of the glucocorticoid receptor in vivo. The Journal of biological chemistry 20020719
One-year trial on safety and normal linear growth with flunisolide HFA in children with asthma. Clinical pediatrics 20020601
Systemic effect comparisons of six inhaled corticosteroid preparations. American journal of respiratory and critical care medicine 20020515
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20020501
The output of flunisolide from different nebulisers. The Journal of pharmacy and pharmacology 20020401
A comparison of methods for assessing hypothalamic-pituitary-adrenal (HPA) axis activity in asthma patients treated with inhaled corticosteroids. Journal of clinical pharmacology 20020301
Single-dose study to compare the pharmacokinetics of HFA flunisolide and CFC flunisolide. Journal of pharmaceutical sciences 20020201
Therapeutic significance of distal airway inflammation in asthma. The Journal of allergy and clinical immunology 20020201
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20020101
Multiple-dose proportionality study of flunisolide hydrofluoroalkane. Allergy and asthma proceedings 20020101
Flunisolide HFA. American journal of respiratory medicine : drugs, devices, and other interventions 20020101
Poor sleep and daytime somnolence in allergic rhinitis: significance of nasal congestion. American journal of respiratory medicine : drugs, devices, and other interventions 20020101
Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3). British journal of pharmacology 20011201
Cost analysis of the use of inhaled corticosteroids in the treatment of asthma: a 1-year follow-up. Respiratory medicine 20011201
Flunisolide HFA vs flunisolide CFC: pharmacokinetic comparison in healthy volunteers. Biopharmaceutics & drug disposition 20011201
Adrenal suppression with inhaled corticosteroids. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011101
Suppression of hypothalamic-pituitary-adrenal axis activity with inhaled flunisolide and fluticasone propionate in adult asthma patients. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011101
Effective control of asthma with hydrofluoroalkane flunisolide delivered as an extrafine aerosol in asthma patients. Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011101
Investigation of the allergenicity of a refined peanut oil-containing topical dermatologic agent in persons who are sensitive to peanuts. Cutis 20010801
Pharmacokinetics of intranasal corticosteroids. The Journal of allergy and clinical immunology 20010701
Improved asthma control after changing from low-to-medium doses of other inhaled corticosteroids to low-dose fluticasone propionate. MedGenMed : Medscape general medicine 20010608
Transactivation of RARE and GRE in the cellular response to arsenic. Molecular and cellular biochemistry 20010601
e-NO peak versus e-NO plateau values in evaluating e-NO production in steroid-naive and in steroid-treated asthmatic children and in detecting response to inhaled steroid treatment. Pediatric pulmonology 20010101
[Antiinflammatory effect of a topical corticosteroid: known brand versus generic drug]. Gaceta medica de Mexico 20010101
Deposition and pharmacokinetics of flunisolide delivered from pressurized inhalers containing non-CFC and CFC propellants. Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20010101
Corticosteroids administered by nebulization to children with bronchial asthma. Advances in therapy 20010101
Safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained delivery device. Investigative ophthalmology & visual science 20001001
Modulation of interleukin-1 alpha mRNA expression in mouse epidermis by tumor promoters and antagonists. Molecular carcinogenesis 19930101
Murine epidermal xanthine oxidase activity: correlation with degree of hyperplasia induced by tumor promoters. Cancer research 19871201
Comparison of amcinonide ointment 0.1 percent twice daily and fluocinonide ointment 0.05 percent three times daily in the treatment of psoriasis. Cutis 19830501
Treatment of psoriasis with amcinonide 0.1 percent and fluocinonide 0.05 percent ointments. A comparative double-blind study. Cutis 19820601
Corticosteroid-induced cutaneous atrophy and telangiectasia. Experimental production associated with weight loss in rats. Archives of dermatology 19760801
The treatment of steroid-induced rosacea and perioral dermatitis. Dermatologica 19760101
Steroid rosacea. Archives of dermatology 19741001
Iatrogenic dermatitis. British medical journal 19691004
Adverse effect of topical fluorinated corticosteroids in rosacea. British medical journal 19690315
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