2-{1,8-diethyl-1H,3H,4H,9H-pyrano[3,4-b]indol-1-yl}acetic acid
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Evaluating the Role of Multidrug Resistance Protein 3 (MDR3) Inhibition in Predicting Drug-Induced Liver Injury Using 125 Pharmaceuticals. | Chemical research in toxicology 20170515 |
Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | Chemical research in toxicology 20150518 |
Assessing the cardiovascular risk between celecoxib and nonselective nonsteroidal antiinflammatory drugs in patients with rheumatoid arthritis and osteoarthritis. | Circulation journal : official journal of the Japanese Circulation Society 20140101 |
Cyclooxygenase 2 and prostaglandin E2 regulate the attachment of calcium oxalate crystals to renal epithelial cells. | International journal of urology : official journal of the Japanese Urological Association 20121001 |
Renal effects of carprofen and etodolac in euvolemic and volume-depleted dogs. | American journal of veterinary research 20120901 |
Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia. | The Journal of pharmacology and experimental therapeutics 20120701 |
Self-organizing molecular field analysis of NSAIDs: assessment of pharmacokinetic and physicochemical properties using 3D-QSPkR approach. | European journal of medicinal chemistry 20120701 |
The effect of renal administration of a selective cyclooxygenase-2 inhibitor or stable prostaglandin I2 analog on the progression of sclerotic glomerulonephritis in rats. | Clinical and experimental nephrology 20120401 |
Spectrofluorimetric determination of etodolac, moxepril HCl and fexofenadine HCl using europium sensitized fluorescence in bulk and pharmaceutical preparations. | Journal of fluorescence 20120101 |
Etodolac blocks the allyl isothiocyanate-induced response in mouse sensory neurons by selective TRPA1 activation. | Pharmacology 20120101 |
The effects of the selective cyclooxygenase-2 inhibitor on endometrial cytological findings in uterine endometrial cancer patients. | Acta cytologica 20120101 |
Effects of a selective COX-2 inhibitor in patients with uterine endometrial cancers. | Archives of gynecology and obstetrics 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Comparative evaluation of efficacy and safety of etodolac and diclofenac sodium injection in patients with postoperative orthopedic pain. | Current medical research and opinion 20111101 |
Acute generalized exanthematous pustulosis due to etodolac in a patient with an iliopsoas muscle abscess. | Acta dermato-venereologica 20110901 |
Etodolac improves 5-FU sensitivity of head and neck cancer cells through inhibition of thymidylate synthase. | Anticancer research 20110901 |
The effect of β-adrenergic blockade and COX-2 inhibition on healing of colon, muscle, and skin in rats undergoing colonic anastomosis. | International journal of clinical pharmacology and therapeutics 20110901 |
In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines. | British journal of cancer 20110726 |
Randomized double-blind trial of sulindac and etodolac to eradicate aberrant crypt foci and to prevent sporadic colorectal polyps. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110601 |
Development and in vitro/in vivo evaluation of etodolac controlled porosity osmotic pump tablets. | AAPS PharmSciTech 20110601 |
Improving postoperative immune status and resistance to cancer metastasis: a combined perioperative approach of immunostimulation and prevention of excessive surgical stress responses. | Annals of surgery 20110401 |
High specific activity tritiation of several biologically active indoles. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20110201 |
Influence of nonsteroidal anti-inflammatory drugs on the antiplatelet effects of aspirin in rats. | Biological & pharmaceutical bulletin 20110101 |
The enantiomers of etodolac, a racemic anti-inflammatory agent, play different roles in efficacy and gastrointestinal safety. | Biological & pharmaceutical bulletin 20110101 |
Effect of beta blocker combined with COX-2 inhibitor on colonic anastomosis in rats. | International journal of colorectal disease 20101201 |
R-etodolac induces E-cadherin and suppresses colitis-related mouse colon tumorigenesis. | Oncology reports 20101201 |
Polymeric surfactant based etodolac chewable tablets: formulation and in vivo evaluation. | AAPS PharmSciTech 20101201 |
Transcription factor NF-κB inhibitors as single therapeutic agents or in combination with classical chemotherapeutic agents for the treatment of hematologic malignancies. | Current molecular pharmacology 20101101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Assessment of the efficacy of pamidronate in ankylosing spondylitis: an open prospective trial. | Singapore medical journal 20101101 |
Efficacy and safety of etodolac-paracetamol fixed dose combination in patients with knee osteoarthritis flare-up: a randomized, double-blind comparative evaluation. | The Clinical journal of pain 20100901 |
A multicentric, randomized, comparative clinical trial to evaluate the efficacy and safety of S-etodolac in the treatment of osteoarthritis in Indian patients. | International journal of clinical pharmacology and therapeutics 20100701 |
In vitro and ex vivo inhibition of canine cyclooxygenase isoforms by robenacoxib: a comparative study. | Research in veterinary science 20100601 |
Sacroiliitis and severe disability due to isotretinoin therapy. | Rheumatology international 20100501 |
Profiling of cell cycle genes of breast cells exposed to etodolac. | Oncology reports 20100501 |
Blurred vision and weakness in a 60-year-old woman. | The American journal of emergency medicine 20100501 |
Chemopreventive activities of etodolac and oxyphenbutazone against mouse skin carcinogenesis. | Bioorganic & medicinal chemistry letters 20100415 |
Preventive effects of etodolac, a selective cyclooxygenase-2 inhibitor, on cancer development in extensive metaplastic gastritis, a Helicobacter pylori-negative precancerous lesion. | International journal of cancer 20100315 |
Improving survival rates in two models of spontaneous postoperative metastasis in mice by combined administration of a beta-adrenergic antagonist and a cyclooxygenase-2 inhibitor. | Journal of immunology (Baltimore, Md. : 1950) 20100301 |
The cyclooxygenase-2 selective inhibitor, etodolac, but not aspirin reduces neovascularization in a murine ischemic hind limb model. | European journal of pharmacology 20100210 |
Enhanced oral bioavailability of etodolac by self-emulsifying systems: in-vitro and in-vivo evaluation. | The Journal of pharmacy and pharmacology 20100201 |
Crystal and molecular structure of beta-cyclodextrins functionalized with the anti-inflammatory drug Etodolac. | Biopolymers 20091201 |
Preparative resolution of etodolac enantiomers by preferential crystallization method. | Archives of pharmacal research 20091001 |
In vitro and in vivo characteristics of a thermogelling rectal delivery system of etodolac. | AAPS PharmSciTech 20090901 |
Racemic Etodolac is cytotoxic and cytostatic for B-cell precursor acute lymphoblastic leukemia cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090801 |
Reversible cerebral vasoconstriction syndrome: case report. | The journal of headache and pain 20090801 |
Evidence-based review of clinical studies on pharmacology (non-anesthetic studies). | Journal of endodontics 20090801 |
Paradoxical effects of a selective cyclooxygenase-2 inhibitor, etodolac, on proliferative changes of forestomach in alloxan-induced diabetic rats. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20090701 |
Etodolac/cyclodextrin formulations: physicochemical characterization and in vivo pharmacological studies. | Drug development and industrial pharmacy 20090701 |
Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells. | European journal of pharmacology 20090610 |
Etodolac attenuates mechanical allodynia in a mouse model of neuropathic pain. | Journal of pharmacological sciences 20090401 |
Cyclooxygenase (COX)-inhibiting drug reduces HSV-1 reactivation in the mouse eye model. | Current eye research 20090301 |
The efficacy of prostaglandin E1 derivative in patients with lumbar spinal stenosis. | Spine 20090115 |
Single dose oral etodolac for acute postoperative pain in adults. | The Cochrane database of systematic reviews 20090101 |
Dextran-etodolac conjugates: synthesis, in vitro and in vivo evaluation. | Acta poloniae pharmaceutica 20090101 |
COX-2 inhibition attenuates cough reflex sensitivity to inhaled capsaicin in patients with asthma. | Journal of investigational allergology & clinical immunology 20090101 |
The risk of acute myocardial infarction with etodolac is not increased compared to naproxen: a historical cohort analysis of a generic COX-2 selective inhibitor. | Journal of cardiovascular pharmacology and therapeutics 20081201 |
Improvement of the etodolac purity test by reversed phase high-performance liquid chromatography. | Die Pharmazie 20081201 |
The effects of etodolac, nimesulid and naproxen sodium on the frequency of sister chromatid exchange after enclused third molars surgery. | Yonsei medical journal 20081031 |
Comparative pharmacological study of free radical scavenger, nitric oxide synthase inhibitor, nitric oxide synthase activator and cyclooxygenase inhibitor against MPTP neurotoxicity in mice. | Metabolic brain disease 20080901 |
Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents. | Bioorganic & medicinal chemistry 20080901 |
Determination of enantiomeric impurity of etodolac by capillary electrophoresis using (2-hydroxypropyl)-beta-cyclodextrin. | Archives of pharmacal research 20080901 |
Chiral non-steroidal anti-inflammatory drugs--a review. | Journal of the Indian Medical Association 20080901 |
The role of non-steroidal anti-inflammatory drugs in the risk of development and treatment of hematologic malignancies. | Leukemia & lymphoma 20080801 |
In vitro inhibition of CYP1A2 by model inhibitors, anti-inflammatory analgesics and female sex steroids: predictability of in vivo interactions. | Basic & clinical pharmacology & toxicology 20080801 |
Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening. | Bioorganic & medicinal chemistry 20080601 |
Analysis of flurbiprofen, ketoprofen and etodolac enantiomers by pre-column derivatization RP-HPLC and application to drug-protein binding in human plasma. | Journal of pharmaceutical and biomedical analysis 20080414 |
Phase I study of a novel pro-apoptotic drug R-etodolac in patients with B-cell chronic lymphocytic leukemia. | Investigational new drugs 20080401 |
Chemopreventive effects of a selective cyclooxygenase-2 inhibitor (etodolac) on chemically induced intraductal papillary carcinoma of the pancreas in hamsters. | Carcinogenesis 20080401 |
Role of interleukin-1beta and tumor necrosis factor-alpha-dependent expression of cyclooxygenase-2 mRNA in thermal hyperalgesia induced by chronic inflammation in mice. | Neuroscience 20080318 |
Development and validation of a high performance liquid chromatography-tandem mass spectrometry for the determination of etodolac in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215 |
Inhibitory effects of the cyclooxygenase-2 inhibitor, etodolac, on colitis-associated tumorigenesis in p53-deficient mice treated with dextran sulfate sodium. | Oncology reports 20080201 |
Etodolac, a selective cyclooxygenase-2 inhibitor, induces upregulation of E-cadherin and has antitumor effect on human bladder cancer cells in vitro and in vivo. | Urology 20080101 |
Spectrophotometric determination of etodolac in pure form and pharmaceutical formulations. | Chemistry Central journal 20080101 |
Combination therapy of S-1 with selective cyclooxygenase-2 inhibitor for liver metastasis of colorectal carcinoma. | Anticancer research 20080101 |
Singlet oxygen scavenging activity of non-steroidal anti-inflammatory drugs. | Redox report : communications in free radical research 20080101 |
Use of liposomes as membrane models to evaluate the contribution of drug-membrane interactions to antioxidant properties of etodolac. | Redox report : communications in free radical research 20080101 |
The effect of etodolac on experimental temporomandibular joint osteoarthritis in dogs. | Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery 20071201 |
Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via reduction of lymphangiogenesis. | Cancer research 20071101 |
SDX-308 and SDX-101, non-steroidal anti-inflammatory drugs, as therapeutic candidates for treating hematologic malignancies including myeloma. | Archiv der Pharmazie 20071001 |
In vitro and ex vivo permeation studies of etodolac from hydrophilic gels and effect of terpenes as enhancers. | Drug delivery 20071001 |
More than meets the eyes. | Journal of the Mississippi State Medical Association 20071001 |
R-etodolac (SDX-101) and the related indole-pyran analogues SDX-308 and SDX-309 potentiate the antileukemic activity of standard cytotoxic agents in primary chronic lymphocytic leukaemia cells. | Cancer chemotherapy and pharmacology 20070901 |
Treatment of multiple myeloma with SDX-308. | Drug news & perspectives 20070901 |
Pharmacological profiling of novel non-COX-inhibiting indole-pyran analogues of etodolac reveals high solid tumour activity of SDX-308 in vitro. | Investigational new drugs 20070801 |
Etodolac-induced pigmenting fixed drug eruption. | Clinical and experimental dermatology 20070501 |
R-Etodolac decreases beta-catenin levels along with survival and proliferation of hepatoma cells. | Journal of hepatology 20070501 |
One center's experience: the serology and drugs associated with drug-induced immune hemolytic anemia--a new paradigm. | Transfusion 20070401 |
Novel etodolac analog SDX-308 (CEP-18082) induces cytotoxicity in multiple myeloma cells associated with inhibition of beta-catenin/TCF pathway. | Leukemia 20070301 |
Safety of selective cyclooxygenase-2 inhibitors and a basic non-steroidal anti-inflammatory drug (NSAID) in Japanese patients with NSAID-induced urticaria and/or angioedema: Comparison of meloxicam, etodolac and tiaramide. | The Journal of dermatology 20070301 |
Evaluation of adverse effects of long-term oral administration of carprofen, etodolac, flunixin meglumine, ketoprofen, and meloxicam in dogs. | American journal of veterinary research 20070301 |
Keratoconjunctivitis sicca associated with administration of etodolac in dogs: 211 cases (1992-2002). | Journal of the American Veterinary Medical Association 20070215 |
Pharmacokinetics of etodolac in the horse following oral and intravenous administration. | Journal of veterinary pharmacology and therapeutics 20070201 |
Overproduction of PGE2 in peripheral blood monocytes of gastrointestinal cancer patients with mucins in their bloodstream. | Cancer letters 20070108 |
Etodolac, a selective cyclooxygenase-2 inhibitor, induces apoptosis by activating caspases in human malignant rhabdoid tumor cells (FRTK-1). | Oncology reports 20070101 |
Membranous nephropathy associated with the relatively selective cyclooxygenase-2 inhibitor, etodolac, in a patient with early rheumatoid arthritis. | Internal medicine (Tokyo, Japan) 20070101 |
Charge transfer complex studies between some non-steroidal anti-inflammatory drugs and pi-electron acceptors. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061201 |
Non-steroidal anti-inflammatory drug therapy for chronic lymphocytic leukemia. | Leukemia & lymphoma 20061201 |
Cytotoxic effect of R-etodolac (SDX-101) in combination with purine analogs or monoclonal antibodies on ex vivo B-cell chronic lymphocytic leukemia cells. | Leukemia & lymphoma 20061201 |
Effects of cyclooxygenase inhibition on the gastrointestinal tract. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20061101 |
Involvement of cyclooxygenase-2 in allergic nasal inflammation in rats. | International immunopharmacology 20061101 |
Case of the month. Chronic hepatitis. | JAAPA : official journal of the American Academy of Physician Assistants 20061101 |
The clinical pharmacology of cyclooxygenase-2-selective and dual inhibitors. | The Veterinary clinics of North America. Small animal practice 20060901 |
Chemoprevention of spontaneous development of hepatocellular carcinomas in fatty liver Shionogi mice by a cyclooxygenase-2 inhibitor. | Cancer science 20060801 |
Etodolac-liquid-filled dispersion into hard gelatin capsules: an approach to improve dissolution and stability of etodolac formulation. | Drug development and industrial pharmacy 20060801 |
High-grade slippage of the lumbar spine in a rat model of spondylolisthesis: effects of cyclooxygenase-2 inhibitor on its deformity. | Spine 20060715 |
In vivo and in vitro cytotoxicity of R-etodolac with dexamethasone in glucocorticoid-resistant multiple myeloma cells. | British journal of haematology 20060701 |
Different progression of tumor xenografts between mucin-producing and mucin-non-producing mammary adenocarcinoma-bearing mice. | Cancer research 20060615 |
Etodolac versus dexamethasone effect in reduction of postoperative symptoms following surgical endodontic treatment: a double-blind study. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20060601 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Depressed-type early invasive colon cancer in a patient treated with cyclooxygenase-2 inhibitor. | Digestive diseases and sciences 20060501 |
Zaltoprofen, a non-steroidal anti-inflammatory drug, inhibits bradykinin-induced pain responses without blocking bradykinin receptors. | Neuroscience research 20060401 |
Use of force plate analysis to assess the analgesic effects of etodolac in horses with navicular syndrome. | American journal of veterinary research 20060401 |
[Intestinal side effects of COX-2 inhibitors]. | Ugeskrift for laeger 20060327 |
Etodolac induces apoptosis and inhibits cell adhesion to bone marrow stromal cells in human myeloma cells. | Leukemia research 20060201 |
Etodolac, a selective cyclooxygenase-2 inhibitor, inhibits liver metastasis of colorectal cancer cells via the suppression of MMP-9 activity. | International journal of molecular medicine 20060201 |
Ocular adverse effects associated with cyclooxygenase-2 inhibitors. | Archives of ophthalmology (Chicago, Ill. : 1960) 20060201 |
[Expression of cyclooxygenase (COX)-2 in astrocytic tumors and anti-tumor effects of selective COX-2 inhibitors]. | No to shinkei = Brain and nerve 20060101 |
Efficacy and safety of preoperative etodolac and butorphanol administration in dogs undergoing ovariohysterectomy. | Journal of the American Animal Hospital Association 20060101 |
[Postoperative pain management in clinics of otolaryngology]. | Kulak burun bogaz ihtisas dergisi : KBB = Journal of ear, nose, and throat 20060101 |
Temporal relationship between use of NSAIDs, including selective COX-2 inhibitors, and cardiovascular risk. | Drug safety 20060101 |
Poststreptococcal reactive arthritis. | Journal of the American Podiatric Medical Association 20060101 |
Efficacy and safety of firocoxib in the management of canine osteoarthritis under field conditions. | Veterinary therapeutics : research in applied veterinary medicine 20060101 |
Combined administration of ethodolac, ascorbic acid and radiotherapy as adjuvant therapies in an extrathoracic desmoid tumor with gross postoperative residual disease; case report and review of the literature. | Journal of B.U.ON. : official journal of the Balkan Union of Oncology 20060101 |
Expression of receptor for advanced glycation end products during rat tongue carcinogenesis by 4-nitroquinoline 1-oxide and effect of a selective cyclooxygenase-2 inhibitor, etodolac. | Pathobiology : journal of immunopathology, molecular and cellular biology 20060101 |
Nonsteroidal anti-inflammatory drugs and their analogues as inhibitors of aldo-keto reductase AKR1C3: new lead compounds for the development of anticancer agents. | Bioorganic & medicinal chemistry letters 20051201 |
Antitumor effects of etodolac, a selective cyclooxygenase-II inhibitor, against human prostate cancer cell lines in vitro and in vivo. | Urology 20051201 |
Prostaglandin production during growth of Candida albicans biofilms. | Journal of medical microbiology 20051101 |
An overview of the recent developments in analytical methodologies for determination of COX-2 inhibitors in bulk drugs, pharmaceuticals and biological matrices. | Journal of pharmaceutical and biomedical analysis 20050915 |
Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the growth inhibition and death in human colon cancer cells. | Biochemical pharmacology 20050901 |
Etodolac inhibits EBER expression and induces Bcl-2-regulated apoptosis in Burkitt's lymphoma cells. | European journal of haematology 20050901 |
Inhibitory effect of etodolac, a selective cyclooxygenase-2 inhibitor, on stomach carcinogenesis in Helicobacter pylori-infected Mongolian gerbils. | Biochemical and biophysical research communications 20050826 |
Cyclooxygenase-2 inhibitor delays fracture healing in rats. | Acta orthopaedica 20050801 |
SDX-101, the R-enantiomer of etodolac, induces cytotoxicity, overcomes drug resistance, and enhances the activity of dexamethasone in multiple myeloma. | Blood 20050715 |
Expression of cyclooxygenase-2 in uterine endometrial cancer and anti-tumor effects of a selective COX-2 inhibitor. | International journal of oncology 20050501 |
In vivo effects of carprofen, deracoxib, and etodolac on prostanoid production in blood, gastric mucosa, and synovial fluid in dogs with chronic osteoarthritis. | American journal of veterinary research 20050501 |
Preferential and non-selective cyclooxygenase inhibitors reduce inflammation during lipopolysaccharide-induced synovitis. | Research in veterinary science 20050401 |
Separation of etodolac enantiomers by capillary electrophoresis. Validation and application of the chiral method to the analysis of commercial formulations. | Electrophoresis 20050301 |
The R-enantiomer of the nonsteroidal antiinflammatory drug etodolac binds retinoid X receptor and induces tumor-selective apoptosis. | Proceedings of the National Academy of Sciences of the United States of America 20050215 |
Chemopreventative effect of a cyclooxygenase-2-specific inhibitor (etodolac) on chemically induced biliary carcinogenesis in hamsters. | Carcinogenesis 20050201 |
Etodolac, a selective cyclo-oxygenase-2 inhibitor, enhances carboplatin-induced apoptosis of human tongue carcinoma cells by down-regulation of FAP-1 expression. | Oral oncology 20050101 |
Anti-inflammatory, antinociceptive, and gastric effects of Hypericum perforatum in rats. | TheScientificWorldJournal 20050101 |
Nonsteroidal antiinflammatory drugs: a review. | Journal of the American Animal Hospital Association 20050101 |
Effects of etodolac on P450 isoform-specific activities in human hepatic microsomes. | Arzneimittel-Forschung 20050101 |
Spectrophotometric study of etodolac complexes with copper (II) and iron (III). | Journal of AOAC International 20050101 |
COX-2-selective inhibitor, etodolac, suppresses choroidal neovascularization in a mice model. | Biochemical and biophysical research communications 20041210 |
Suppressive effects of a selective cyclooxygenase-2 inhibitor, etodolac, on 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20041201 |
Carboxyl nonsteroidal anti-inflammatory drugs are efficiently glucuronidated by microsomes of the human gastrointestinal tract. | Biochimica et biophysica acta 20041118 |
Risks of clinically significant upper gastrointestinal events with etodolac and naproxen: a historical cohort analysis. | Gastroenterology 20041101 |
Novel cyclooxygenase-1 inhibitors discovered using affinity fingerprints. | Journal of medicinal chemistry 20040923 |
Warning of an adverse effect of etodolac. | Journal of the American Veterinary Medical Association 20040815 |
Adverse drug event reports at the United States Food And Drug Administration Center for Veterinary Medicine. | Journal of the American Veterinary Medical Association 20040815 |
Involvement of cell cycle regulatory proteins and MAP kinase signaling pathway in growth inhibition and cell cycle arrest by a selective cyclooxygenase 2 inhibitor, etodolac, in human hepatocellular carcinoma cell lines. | Cancer science 20040801 |
Pharmacokinetic difference between S-(+)- and R-(-)-etodolac in rats. | Acta pharmacologica Sinica 20040801 |
Effect of etodolac, a COX-2 inhibitor, on neuropathic pain in a rat model. | Brain research 20040604 |
Inhibition of HER-kinase activation prevents ERK-mediated degradation of PPARgamma. | Cancer cell 20040601 |
Effects of flunixin meglumine or etodolac treatment on mucosal recovery of equine jejunum after ischemia. | American journal of veterinary research 20040601 |
Determination of expression of cyclooxygenase-1 and -2 isozymes in canine tissues and their differential sensitivity to nonsteroidal anti-inflammatory drugs. | American journal of veterinary research 20040601 |
[A case of rheumatoid arthritis/Sjogren's syndrome with acute renal failure due to hyperuricemia associated with mizoribine therapy]. | Nihon Rinsho Men'eki Gakkai kaishi = Japanese journal of clinical immunology 20040601 |
Inhibitory effects of etodolac, a selective COX-2 inhibitor, on the occurrence of tumors in colitis-induced tumorigenesis model in rats. | Oncology reports 20040501 |
Stereoselective glucuronidation and hydroxylation of etodolac by UGT1A9 and CYP2C9 in man. | Xenobiotica; the fate of foreign compounds in biological systems 20040501 |
MCF-7 breast cancer cell line grown in agarose culture for study of COX-2 inhibitors in three-dimensional growth system. | Cancer letters 20040308 |
Patient retention and hand-wrist radiograph progression of rheumatoid arthritis during a 3-year prospective study that prohibited disease modifying antirheumatic drugs. | The Journal of rheumatology 20040301 |
Sequence-dependent effect of a cyclooxygenase-2 inhibitor on topoisomerase I inhibitor and 5-fluorouracil-induced cytotoxicity of colon cancer cells. | Anti-cancer drugs 20040301 |
Efficacy of transdermal nitroglycerin combined with etodolac for the treatment of chronic post-thoracotomy pain: an open-label prospective clinical trial. | Journal of pain and symptom management 20040301 |
Combined treatment with selective cyclooxygenase-2 inhibitor and fluorinated pyrimidines for liver metastasis of colon cancer. | Oncology reports 20040101 |
Secondary hypertrophic osteoarthropathy (HOA) mimicking primary HOA (pachydermoperiostitis or Touraine-Solente-Golé) syndrome. | The Israel Medical Association journal : IMAJ 20040101 |
Oral etodolac, a COX-2 inhibitor, reduces postoperative pain immediately after fast-track cardiac surgery. | Journal of anesthesia 20040101 |
In vitro effects of selective and non-selective nonsteroidal anti-inflammatory drugs on the frequency of sister chromatid exchanges. | Drugs in R&D 20040101 |
Identification and prediction of promiscuous aggregating inhibitors among known drugs. | Journal of medicinal chemistry 20031009 |
Effects of a single arthrocentesis and a COX-2 inhibitor on disorders of temporomandibular joints. A preliminary clinical study. | The British journal of oral & maxillofacial surgery 20031001 |
Inhibitory effects of selective cyclooxygenase-2 inhibitors, nimesulide and etodolac, on the development of squamous cell dysplasias and carcinomas of the tongue in rats initiated with 4-nitroquinoline 1-oxide. | Cancer letters 20030925 |
[Combined treatment with fluorinated pyrimidines and selective cyclooxygenase-2 inhibitors for liver metastasis of colon cancer]. | Nihon rinsho. Japanese journal of clinical medicine 20030901 |
Anti-inflammatory effect and low ulcerogenic activity of etodolac, a cyclooxygenase-2 selective non-steroidal anti-inflammatory drug, on adjuvant-induced arthritis in rats. | Pharmacology 20030601 |
Colon cancer cells with high invasive potential are susceptible to induction of apoptosis by a selective COX-2 inhibitor. | Cancer science 20030301 |
Review article: NSAIDs, gastroprotection and cyclo-oxygenase-II-selective inhibitors. | Alimentary pharmacology & therapeutics 20030201 |
Pain treatment with a COX-2 inhibitor after coronary artery bypass operation: a randomized trial. | The Annals of thoracic surgery 20030201 |
Double-blind, randomised, comparative trial of etodolac SR versus diclofenac in the treatment of osteoarthritis of the knee. | Current medical research and opinion 20030101 |
Superficially elevated colonic adenoma changed to undetectable configuration on ordinary endoscopy during treatment with preferential cyclooxygenase-2 inhibitor. | Journal of gastroenterology 20030101 |
Effect of dosing and sampling time on serum thyroxine, free thyroxine, and thyrotropin concentrations in dogs following multidose etodolac administration. | Veterinary therapeutics : research in applied veterinary medicine 20030101 |
A study of the comparative efficacy of three common analgesics in the control of pain after third molar surgery under local anaesthesia. | Australian dental journal 20021201 |
Selective cyclooxygenase-2 inhibitors show a differential ability to inhibit proliferation and induce apoptosis of colon adenocarcinoma cells. | FEBS letters 20021106 |
Results of thyroid function tests and concentrations of plasma proteins in dogs administered etodolac. | American journal of veterinary research 20021101 |
In vitro investigation of the effects of cyclooxygenase-2 inhibitors on contractile activity of the equine dorsal and ventral colon. | American journal of veterinary research 20021101 |
Cyclooxygenase-2 inhibitor inhibits the fracture healing. | Journal of physiological anthropology and applied human science 20020901 |
The effects of cyclo-oxygenase inhibitors on bile-injured and normal equine colon. | Equine veterinary journal 20020701 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Enhanced clearance of leukemic lymphocytes in B-cell chronic lymphocytic leukemia with etodolac. | Blood 20020401 |
Regulation of prostaglandin production in an immortalized human myometrial cell line by cytokines and non-steroidal anti-inflammatory drugs. | European journal of obstetrics, gynecology, and reproductive biology 20020110 |
Effects of etodolac, a selective cyclooxygenase-2 inhibitor, on the expression of E-cadherin-catenin complexes in gastrointestinal cell lines. | Journal of gastroenterology 20020101 |
Search of antimicrobial activity of selected non-antibiotic drugs. | Acta poloniae pharmaceutica 20020101 |
Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes. | The Journal of pharmacy and pharmacology 20011201 |
Regioselective biomimetic oxidation of etodolac with iodosylbenzene catalyzed by halogenated and perhalogenated metalloporphyrins in dichloromethane. | Chemical & pharmaceutical bulletin 20011001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control. | Medicine and health, Rhode Island 20011001 |
Comparison of the upper gastrointestinal effects of etodolac and aspirin in healthy dogs. | The Journal of veterinary medical science 20011001 |
Does cyclooxygenase-2 inhibitor prevent renal tissue damage in unilateral ureteral obstruction? | The Journal of urology 20010901 |
Cyclooxygenase selectivity of non-steroid anti-inflammatory drugs in humans: ex vivo evaluation. | European journal of pharmacology 20010824 |
Long-term temporal evaluation of ground reaction forces during development of experimentally induced osteoarthritis in dogs. | American journal of veterinary research 20010801 |
Isolation of an unknown metabolite of the non-steroidal anti-inflammatory drug etodolac and its identification as 5-hydroxy etodolac. | Journal of pharmaceutical and biomedical analysis 20010701 |
Induction of apoptosis by cyclooxygenase-2 inhibitors in prostate cancer cell lines. | International journal of urology : official journal of the Japanese Urological Association 20010701 |
Effects of cyclooxygenase-2 inhibitor on gastric acid secretion in Helicobacter pylori-infected C57BL/6 mice. | Scandinavian journal of gastroenterology 20010601 |
Tumor invasiveness and liver metastasis of colon cancer cells correlated with cyclooxygenase-2 (COX-2) expression and inhibited by a COX-2-selective inhibitor, etodolac. | International journal of cancer 20010315 |
Direct superoxide scavenging activity of nonsteroidal anti-inflammatory drugs: determination by electron spin resonance using the spin trap method. | Headache 20010201 |
[Suppressive efffects of clarithromycin and cyclooxygenase-2 inhibitor, etodolac on N-nitrosobis(2-hydroxypropyl)amine(BHP)- induced experimental lung neoplasm in rats]. | The Japanese journal of antibiotics 20010201 |
Nimesulide, a balanced drug for the treatment of osteoarthritis. | Clinical and experimental rheumatology 20010101 |
The role of eicosanoids in the process of adaptation following massive bowel resection in the rat. | JPEN. Journal of parenteral and enteral nutrition 20010101 |
The effect of etodolac on bile salt and histamine-mediated gastric mucosal injury in the rat. | Journal of physiology, Paris 20010101 |
Effects of some pharmacological agents on the survival of unipedicled venous flaps: an experimental study. | Microsurgery 20010101 |
Sulindac and a cyclooxygenase-2 inhibitor, etodolac, increase APC mRNA in the colon of rats treated with azoxymethane. | Gut 20001201 |
Immune hemolytic anemia caused by sensitivity to a metabolite of etodolac, a nonsteroidal anti-inflammatory drug. | Transfusion 20000601 |
The effect of NSAIDs and a COX-2 specific inhibitor on Helicobacter pylori-induced PGE2 and HGF in human gastric fibroblasts. | Alimentary pharmacology & therapeutics 20000401 |
Reactive oxygen species are involved in the apoptosis induced by nonsteroidal anti-inflammatory drugs in cultured gastric cells. | European journal of pharmacology 19991103 |
Biochemical and pharmacological profile of a tetrasubstituted furanone as a highly selective COX-2 inhibitor. | British journal of pharmacology 19970501 |
Nonsteroidal antiinflammatory drug induced hypersensitivity vasculitis clinically mimicking temporal arteritis. | The Journal of rheumatology 19960101 |
Fulminant hepatic failure associated with etodolac use. | The American journal of gastroenterology 19950401 |
Anti-inflammatory effects of etodolac: comparison with other non-steroidal anti-inflammatory drugs. | Biological & pharmaceutical bulletin 19941201 |
Efficacy and tolerability of etodolac in aged patients affected by degenerative joint disease (osteoarthritis) in its active phase. | International journal of clinical pharmacology research 19940101 |
[Allergic vasculitis caused by etodolac. The first case]. | Annales de medecine interne 19890101 |
Comparative effects of etodolac, indomethacin, and benoxaprofen on icosanoid biosynthesis. | Inflammation 19841201 |