Ethyl 4-chloroacetoacetate
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Development of a substrate-coupled biocatalytic process driven by an NADPH-dependent sorbose reductase from Candida albicans for the asymmetric reduction of ethyl 4-chloro-3-oxobutanoate. | Biotechnology letters 20121201 |
Overexpression and characterization of a novel (S)-specific extended short-chain dehydrogenase/reductase from Candida parapsilosis. | Bioresource technology 20121101 |
Microwave-assisted synthesis of cyclopentanones using the relevant phosphorus ylides. | Combinatorial chemistry & high throughput screening 20120501 |
Expression, purification, crystallization and preliminary X-ray analysis of carbonyl reductase S1 from Candida magnoliae. | Acta crystallographica. Section F, Structural biology and crystallization communications 20120501 |
[Cloning, expression and characterization of chiral alcohol dehydrogenase from Rhodococcus erythropolis ATCC 4277]. | Wei sheng wu xue bao = Acta microbiologica Sinica 20120101 |
Robust optimization of alginate-Carbopol 940 bead formulations. | TheScientificWorldJournal 20120101 |
A novel reductase from Candida albicans for the production of ethyl (S)-4-chloro-3-hydroxybutanoate. | Bioscience, biotechnology, and biochemistry 20120101 |
Novel carbon-carbon bond formations for biocatalysis. | Current opinion in biotechnology 20111201 |
Highly stereoselective reduction of prochiral ketones by a bacterial reductase coupled with cofactor regeneration. | Organic & biomolecular chemistry 20110807 |
Highly efficient synthesis of chiral alcohols with a novel NADH-dependent reductase from Streptomyces coelicolor. | Bioresource technology 20110701 |
Novel anti-Prelog stereospecific carbonyl reductases from Candida parapsilosis for asymmetric reduction of prochiral ketones. | Organic & biomolecular chemistry 20110607 |
Biochemical characterisation of a NADPH-dependent carbonyl reductase from Neurospora crassa reducing α- and β-keto esters. | Enzyme and microbial technology 20110506 |
Ethyl (2E)-2-(2H-1,3-benzodioxol-5-yl-methyl-idene)-4-chloro-3-oxobutano-ate. | Acta crystallographica. Section E, Structure reports online 20110501 |
Purification and characterization of a novel NADH-dependent carbonyl reductase from Pichia stipitis involved in biosynthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate. | Bioresource technology 20110101 |
First synthesis of 2-(benzofuran-2-yl)-6,7-methylene dioxyquinoline-3-carboxylic acid derivatives. | Beilstein journal of organic chemistry 20110101 |
High-yield production of biologically active recombinant protein in shake flask culture by combination of enzyme-based glucose delivery and increased oxygen transfer. | Microbial cell factories 20110101 |
Biocatalytic synthesis of (S)-4-chloro-3-hydroxybutanoate ethyl ester using a recombinant whole-cell catalyst. | Applied microbiology and biotechnology 20101201 |
Biosynthesis of (S)-4-chloro-3-hydroxybutanoate ethyl using Escherichia coli co-expressing a novel NADH-dependent carbonyl reductase and a glucose dehydrogenase. | Bioresource technology 20101101 |
Construction and co-expression of a polycistronic plasmid encoding carbonyl reductase and glucose dehydrogenase for production of ethyl (S)-4-chloro-3-hydroxybutanoate. | Bioresource technology 20100901 |
Enantioselective bioconversion using Escherichia coli cells expressing Saccharomyces cerevisiae reductase and Bacillus subtilis glucose dehydrogenase. | Journal of microbiology and biotechnology 20100901 |
High-level production of heterologous proteins using untreated cane molasses and corn steep liquor in Escherichia coli medium. | Applied microbiology and biotechnology 20100601 |
Purification, cloning, and overexpression of an alcohol dehydrogenase from Nocardia globerula reducing aliphatic ketones and bulky ketoesters. | Applied microbiology and biotechnology 20100501 |
Asymmetric synthesis of (S)-ethyl-4-chloro-3-hydroxybutanoate using Candida parapsilosis ATCC 7330. | Journal of industrial microbiology & biotechnology 20100201 |
Synthesis of the marine pyrroloiminoquinone alkaloids, discorhabdins. | Marine drugs 20100101 |
Molecular cloning and biochemical characterization of a novel erythrose reductase from Candida magnoliae JH110. | Microbial cell factories 20100101 |
A new member of the short-chain dehydrogenases/reductases superfamily: purification, characterization and substrate specificity of a recombinant carbonyl reductase from Pichia stipitis. | Bioresource technology 20091201 |
A novel carbonyl reductase from Pichia stipitis for the production of ethyl (S)-4-chloro-3-hydroxybutanoate. | Biotechnology letters 20090401 |
Biosimulation of drug metabolism--a yeast based model. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090131 |
Asymmetric reduction of prochiral ketones to chiral alcohols catalyzed by plants tissue. | Journal of industrial microbiology & biotechnology 20080901 |
Improvement of natural isolates of Saccharomyces cerevisiae strains for synthesis of a chiral building block using classic genetics. | Applied microbiology and biotechnology 20080301 |
(Z)-Ethyl 4-chloro-2-[(4-chloro-phen-yl)hydrazono]-3-oxobutanoate. | Acta crystallographica. Section E, Structure reports online 20080201 |
Whole-cell bioreduction of aromatic alpha-keto esters using Candida tenuis xylose reductase and Candida boidinii formate dehydrogenase co-expressed in Escherichia coli. | Microbial cell factories 20080101 |
Engineering the phenylacetaldehyde reductase mutant for improved substrate conversion in the presence of concentrated 2-propanol. | Applied microbiology and biotechnology 20071201 |
Bioconversion of ethyl 4-chloro-3-oxobutanoate by permeabilized fresh brewer's yeast cells in the presence of allyl bromide. | Journal of industrial microbiology & biotechnology 20070201 |
Construction of a two-strain system for asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to (S)-4-chloro-3-hydroxybutanoate ethyl ester. | Applied microbiology and biotechnology 20060301 |
X-ray structures of NADPH-dependent carbonyl reductase from Sporobolomyces salmonicolor provide insights into stereoselective reductions of carbonyl compounds. | Journal of molecular biology 20050923 |
Comparison of (+)- and (-)-hemipalmitoylcarnitinium as inhibitors of hepatic mitochondrial carnitine palmitoyltransferases in diabetic rats. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20050901 |
Robust NADH-regenerator: improved alpha-haloketone-resistant formate dehydrogenase. | Applied microbiology and biotechnology 20050401 |
Asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate with two co-existing, recombinant Escherichia coli strains. | Biotechnology letters 20050101 |
Efficient production of recombinant aldehyde reductase and its application for asymmetric reduction of ethyl 4-chloro-3-oxobutanoate to ethyl (R)-4-chloro-3-hydroxybutanoate. | Preparative biochemistry & biotechnology 20050101 |
A novel NADH-dependent carbonyl reductase from Kluyveromyces aestuarii and comparison of NADH-regeneration system for the synthesis of ethyl (S)-4-chloro-3-hydroxybutanoate. | Bioscience, biotechnology, and biochemistry 20040301 |
Fungal aerobic reductive dechlorination of ethyl 2-chloroacetoacetate by Saccharomyces cerevisiae: mechanism of a novel type of microbial dehalogenation. | Chembiochem : a European journal of chemical biology 20040103 |
Purification and characterization of an alpha-haloketone-resistant formate dehydrogenase from Thiobacillus sp. strain KNK65MA, and cloning of the gene. | Bioscience, biotechnology, and biochemistry 20031001 |
Purification and properties of a carbonyl reductase involved in stereoselective reduction of ethyl 4-chloro-3-oxobutanoate from Cylindrocarpon sclerotigenum IFO 31855. | Bioscience, biotechnology, and biochemistry 20030601 |
Synthesis of ethyl ( S)-4-chloro-3-hydroxybutanoate using fabG-homologues. | Applied microbiology and biotechnology 20030401 |
Applying the Taguchi robust design to the optimization of the asymmetric reduction of ethyl 4-chloro acetoacetate by bakers' yeast. | Journal of biotechnology 20030213 |
Applying slow-release biocatalysis to the asymmetric reduction of ethyl 4-chloroacetoacetate. | Biotechnology letters 20030101 |
Purification and properties of a carbonyl reductase useful for production of ethyl (S)-4-chloro-3-hydroxybutanoate from Kluyveromyces lactis. | Bioscience, biotechnology, and biochemistry 20020801 |
Chiral alcohol production by NADH-dependent phenylacetaldehyde reductase coupled with in situ regeneration of NADH. | European journal of biochemistry 20020501 |
Synthesis of ethyl (R)-4-chloro-3-hydroxybutanoate with recombinant Escherichia coli cells expressing (S)-specific secondary alcohol dehydrogenase. | Bioscience, biotechnology, and biochemistry 20020201 |
Design of the pH profile for asymmetric bioreduction of ethyl 4-chloro-3-oxobutyrate on the basis of a data-driven method. | Biotechnology progress 20020101 |
Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by fungi. | Bioscience, biotechnology, and biochemistry 20010701 |
Synthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate by Escherichia coli transformant cells coexpressing the carbonyl reductase and glucose dehydrogenase genes. | Applied microbiology and biotechnology 20010501 |