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Copper(ii) chloride

CAS No.:
7447-39-4
Catalog Number:
AG0034N0
Molecular Formula:
Cl2Cu
Molecular Weight:
134.4520
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
95%
In Stock USA
United States
$13
- +
25g
95%
In Stock USA
United States
$19
- +
100g
95%
In Stock USA
United States
$50
- +
250g
98%
In Stock USA
United States
$73
- +
Product Description
Catalog Number:
AG0034N0
Chemical Name:
Copper(ii) chloride
CAS Number:
7447-39-4
Molecular Formula:
Cl2Cu
Molecular Weight:
134.4520
MDL Number:
MFCD00149676
IUPAC Name:
dichlorocopper
InChI:
InChI=1S/2ClH.Cu/h2*1H;/q;;+2/p-2
InChI Key:
ORTQZVOHEJQUHG-UHFFFAOYSA-L
SMILES:
[Cl-].[Cl-].[Cu+2]
NSC Number:
165706
UN Number:
2802
Properties
Complexity:
2.8  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
132.867g/mol
Formal Charge:
0
Heavy Atom Count:
3  
Hydrogen Bond Acceptor Count:
0
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
134.446g/mol
Monoisotopic Mass:
132.867g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Hippocampal Subcellular Organelle Proteomic Alteration of Copper-Treated Mice. Toxicological sciences : an official journal of the Society of Toxicology 20180701
Copper-redox cycling by coumarin-di(2-picolyl)amine hybrid molecule leads to ROS-mediated DNA damage and apoptosis: A mechanism for cancer chemoprevention. Chemico-biological interactions 20180625
Nickel ions bind to HSP90β and enhance HIF-1α-mediated IL-8 expression. Toxicology 20180215
Mechanisms of redox interactions of bilirubin with copper and the effects of penicillamine. Chemico-biological interactions 20171225
Copper Inhibits the AlkB Family DNA Repair Enzymes under Wilson's Disease Condition. Chemical research in toxicology 20171016
Neurobehavioral alterations plus transcriptional changes of the heat shock protein 90 and hypoxia inducible factor-1α in the crucian carp exposed to copper. Neurotoxicology 20160101
Ziram and sodium N,N-dimethyldithiocarbamate inhibit ubiquitin activation through intracellular metal transport and increased oxidative stress in HEK293 cells. Chemical research in toxicology 20150420
Copper-induced immunotoxicity involves cell cycle arrest and cell death in the liver. Environmental toxicology 20150401
Elevated copper ion levels as potential cause of impaired kinesin-dependent transport processes. Archives of toxicology 20150401
Omeprazole, a gastric proton pump inhibitor, inhibits melanogenesis by blocking ATP7A trafficking. The Journal of investigative dermatology 20150301
Peptides derived from the copper-binding region of lysyl oxidase exhibit antiangiogeneic properties by inhibiting enzyme activity: an in vitro study. Journal of peptide science : an official publication of the European Peptide Society 20141101
Cytotoxic effects of pyrrolidine dithiocarbamate in small-cell lung cancer cells, alone and in combination with cisplatin. International journal of oncology 20141001
Detection of increased 64Cu uptake by human copper transporter 1 gene overexpression using PET with 64CuCl2 in human breast cancer xenograft model. Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20141001
Uptake of compounds that selectively kill multidrug-resistant cells: the copper transporter SLC31A1 (CTR1) increases cellular accumulation of the thiosemicarbazone NSC73306. Molecular pharmaceutics 20140804
Loss of COMMD1 and copper overload disrupt zinc homeostasis and influence an autism-associated pathway at glutamatergic synapses. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20140801
Preventive effect of CuCl₂ on behavioral alterations and mercury accumulation in central nervous system induced by HgCl2 in newborn rats. Journal of biochemical and molecular toxicology 20140701
Regulation of copper transport crossing brain barrier systems by Cu-ATPases: effect of manganese exposure. Toxicological sciences : an official journal of the Society of Toxicology 20140601
The transcriptomic response to copper exposure by the gill tissue of Japanese scallops (Mizuhopecten yessoensis) using deep-sequencing technology. Fish & shellfish immunology 20140601
Genes involved in cysteine metabolism of Chironomus tepperi are regulated differently by copper and by cadmium. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20140501
Understanding copper sensitivity in zebrafish (Danio rerio) through the intracellular localization of copper transporters in a hepatocyte cell-line ZFL and the tissue expression profiles of copper transporters. Metallomics : integrated biometal science 20140501
Subneurotoxic copper(II)-induced NF-κB-dependent microglial activation is associated with mitochondrial ROS. Toxicology and applied pharmacology 20140415
Disulfiram is a direct and potent inhibitor of human O6-methylguanine-DNA methyltransferase (MGMT) in brain tumor cells and mouse brain and markedly increases the alkylating DNA damage. Carcinogenesis 20140301
Involvement of CTR1 and ATP7A in lead (Pb)-induced copper (Cu) accumulation in choroidal epithelial cells. Toxicology letters 20140210
Interference of CuO nanoparticles with metal homeostasis in hepatocytes under sub-toxic conditions. Nanoscale 20140101
The Copper Metabolism MURR1 domain protein 1 (COMMD1) modulates the aggregation of misfolded protein species in a client-specific manner. PloS one 20140101
Transcription patterns of genes encoding four metallothionein homologs in Daphnia pulex exposed to copper and cadmium are time- and homolog-dependent. Aquatic toxicology (Amsterdam, Netherlands) 20131015
Synthesis, structure and antifungal activity of thiophene-2,3-dicarboxaldehyde bis(thiosemicarbazone) and nickel(II), copper(II) and cadmium(II) complexes: unsymmetrical coordination mode of nickel complex. Journal of inorganic biochemistry 20130901
Biomarkers of waterborne copper exposure in the guppy Poecilia vivipara acclimated to salt water. Aquatic toxicology (Amsterdam, Netherlands) 20130815
Effect of copper exposure on GST activity and on the expression of four GSTs under oxidative stress condition in the monogonont rotifer, Brachionus koreanus. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20130801
Copper-induced deregulation of microRNA expression in the zebrafish olfactory system. Environmental science & technology 20130702
Differential effects of metal contamination on the transcript expression of immune- and stress-response genes in the Sydney Rock oyster, Saccostrea glomerata. Environmental pollution (Barking, Essex : 1987) 20130701
Copper induced immunotoxicity promote differential apoptotic pathways in spleen and thymus. Toxicology 20130405
Lysyl oxidase and enhancement of cell proliferation and angiogenesis in oral squamous cell carcinoma. Head & neck 20130201
Evaluation of topically applied copper(II) oxide nanoparticle cytotoxicity in human skin organ culture. Toxicology in vitro : an international journal published in association with BIBRA 20130201
Copper stabilizes the Menkes copper-transporting ATPase (Atp7a) protein expressed in rat intestinal epithelial cells. American journal of physiology. Cell physiology 20130201
Contributions of rat Ctr1 to the uptake and toxicity of copper and platinum anticancer drugs in dorsal root ganglion neurons. Biochemical pharmacology 20130115
A study of molecular structure and vibrational spectra of copper(II) halide complex of 2-(2'-thienyl)pyridine. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001
Pd(II)-mediated cyclization of o-allylbenzaldehydes in water: a novel synthesis of isocoumarins. Organic letters 20120921
Effectiveness of copper chloride in protecting against alterations induced by mercury chloride in newborn rats. Journal of biochemical and molecular toxicology 20120901
Protecting-group-free synthesis of glycosyl 1-phosphates. Organic letters 20120817
Nuclear translocation of DJ-1 during oxidative stress-induced neuronal cell death. Free radical biology & medicine 20120815
Identification of hepatic copper-binding proteins from tilapia by column chromatography with proteomic approaches. Metallomics : integrated biometal science 20120801
Mixed metal copper(II)-nickel(II) and copper(II)-zinc(II) complexes of multihistidine peptide fragments of human prion protein. Journal of inorganic biochemistry 20120701
The effects of chronic copper exposure on the amyloid protein metabolisim associated genes' expression in chronic cerebral hypoperfused rats. Neuroscience letters 20120614
Casiopeina II-gly and bromo-pyruvate inhibition of tumor hexokinase, glycolysis, and oxidative phosphorylation. Archives of toxicology 20120501
Leishmania amazonensis: inhibition of 3'-nucleotidase activity by Cu2+ ions. Experimental parasitology 20120501
A simple and efficient fluorescent sensor for histidine. Chemical communications (Cambridge, England) 20120407
Expression profiles of seven glutathione S-transferase (GST) genes from Venerupis philippinarum exposed to heavy metals and benzo[a]pyrene. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120401
Mutational analysis of cysteine 328 and cysteine 368 at the interface of Plasmodium falciparum adenylosuccinate synthetase. Biochimica et biophysica acta 20120401
New CuCl2-induced glucoside esters and other constituents from Portucala oleracea. Carbohydrate research 20120401
Copper can still be epitaxially deposited on palladium nanocrystals to generate core-shell nanocubes despite their large lattice mismatch. ACS nano 20120327
Copper-induced immunotoxicity involves cell cycle arrest and cell death in the spleen and thymus. Toxicology 20120311
Effect of Cu-nanoparticles versus Cu-salt in Enchytraeus albidus (Oligochaeta): differential gene expression through microarray analysis. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20120301
Proteomic discovery of biomarkers of metal contamination in Sydney Rock oysters (Saccostrea glomerata). Aquatic toxicology (Amsterdam, Netherlands) 20120301
Contribution of nano-copper particles to in vivo liver dysfunction and cellular damage: role of IκBα/NF-κB, MAPKs and mitochondrial signal. Nanotoxicology 20120201
Copper export from cultured astrocytes. Neurochemistry international 20120201
Free-radical degradation of high-molar-mass hyaluronan induced by ascorbate plus cupric ions: evaluation of antioxidative effect of cysteine-derived compounds. Chemistry & biodiversity 20120201
Rectangular coordination polymer nanoplates: large-scale, rapid synthesis and their application as a fluorescent sensing platform for DNA detection. PloS one 20120101
Copper and bezafibrate cooperate to rescue cytochrome c oxidase deficiency in cells of patients with SCO2 mutations. Orphanet journal of rare diseases 20120101
Antibacterial properties of PES/CuCl(2) three-bore hollow fiber UF membrane. Water science and technology : a journal of the International Association on Water Pollution Research 20120101
Formation of diclofenac molecular ions as the effect of Cu(2+)-π interaction under electrospray ionization mass spectrometry conditions. European journal of mass spectrometry (Chichester, England) 20120101
Prenatal treatment of mosaic mice (Atp7a mo-ms) mouse model for Menkes disease, with copper combined by dimethyldithiocarbamate (DMDTC). PloS one 20120101
Inhibition of TDP-43 accumulation by bis(thiosemicarbazonato)-copper complexes. PloS one 20120101
Effect of Gly-Gly-His, Gly-His-Lys and their copper complexes on TNF-alpha-dependent IL-6 secretion in normal human dermal fibroblasts. Acta poloniae pharmaceutica 20120101
Disulfiram/copper complex activated JNK/c-jun pathway and sensitized cytotoxicity of doxorubicin in doxorubicin resistant leukemia HL60 cells. Blood cells, molecules & diseases 20111215
In vitro effect of copper chloride exposure on reactive oxygen species generation and respiratory chain complex activities of mitochondria isolated from broiler liver. Biological trace element research 20111201
High copper levels promotes broiler hepatocyte mitochondrial permeability transition in vivo and in vitro. Biological trace element research 20111201
Oral administration of copper to rats leads to increased lymphocyte cellular DNA degradation by dietary polyphenols: implications for a cancer preventive mechanism. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20111201
Copper(II) chloride mediated synthesis and DNA photocleavage activity of 1-aryl/heteroaryl-4-substituted-1,2,4-triazolo[4,3-a]quinoxalines. European journal of medicinal chemistry 20111201
Menkes disease and infantile epilepsy. Brain & development 20111101
Copper-catalyzed C(sp3)-C(sp3) bond formation using a hypervalent iodine reagent: an efficient allylic trifluoromethylation. Journal of the American Chemical Society 20111019
Effects of Cu2O nanoparticle and CuCl2 on zebrafish larvae and a liver cell-line. Aquatic toxicology (Amsterdam, Netherlands) 20111001
CuCl2-promoted 6-endo-dig chlorocyclization and oxidative aromatization cascade: efficient construction of 1-azaanthraquinones from N-propargylaminoquinones. Organic letters 20110819
Differentially expressed proteins in zebrafish liver cells exposed to copper. Aquatic toxicology (Amsterdam, Netherlands) 20110801
Copper-treatment increases the cellular GSH content and accelerates GSH export from cultured rat astrocytes. Neuroscience letters 20110701
Cell growing density affects the structural and functional properties of Caco-2 differentiated monolayer. Journal of cellular physiology 20110601
Myricetin: a naturally occurring regulator of metal-induced amyloid-β aggregation and neurotoxicity. Chembiochem : a European journal of chemical biology 20110516
Indicator approach to develop a chemosensor for the colorimetric sensing of thiol-containing water and its application for the thiol detection in plasma. The Analyst 20110507
Clusterin (apolipoprotein J), a molecular chaperone that facilitates degradation of the copper-ATPases ATP7A and ATP7B. The Journal of biological chemistry 20110325
Copper(II)chloride-mediated cyclization reaction of N-alkoxy-ortho-alkynylbenzamides. Organic letters 20110204
Adsorption of low-density lipoprotein, its oxidation, and subsequent binding of specific recombinant antibodies: An in situ ellipsometric study. Biochimica et biophysica acta 20110201
Linking molecular biomarkers with higher level condition indicators to identify effects of copper exposures on the endangered delta smelt (Hypomesus transpacificus). Environmental toxicology and chemistry 20110201
Zebrafish sod1 and sp1 expression are modulated by the copper ATPase gene atp7a in response to intracellular copper status. Chemico-biological interactions 20110201
A novel dithiocarbamate analogue with potentially decreased ALDH inhibition has copper-dependent proteasome-inhibitory and apoptosis-inducing activity in human breast cancer cells. Cancer letters 20110101
New stress metabolite from Bulbophyllum kwangtungense. Natural product communications 20110101
Glutathione level of Desulfovibrio desulfuricans IMV K-6 under the influence of heavy metal salts. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20110101
Pyrrolidine dithiocarbamate (PDTC)/Cu complex induces lung epithelial cell apoptosis through mitochondria and ER-stress pathways. Toxicology letters 20101215
Prediction of the contact sensitizing potential of chemicals using analysis of gene expression changes in human THP-1 monocytes. Toxicology letters 20101110
One-pot highly stereoselective synthesis of cyano aziridines via the CuCl-catalyzed aminochlorination of α,β-unsaturated nitriles and intramolecular S(N) 2 substitution. Chemical biology & drug design 20101101
Coordination properties of ionic liquid-mediated chromium(II) and copper(II) chlorides and their complexes with glucose. Inorganic chemistry 20101101
Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B. The Journal of biological chemistry 20100827
Redox cycling of catechol estrogens generating apurinic/apyrimidinic sites and 8-oxo-deoxyguanosine via reactive oxygen species differentiates equine and human estrogens. Chemical research in toxicology 20100816
Apoptosis and necroptosis are induced in rainbow trout cell lines exposed to cadmium. Aquatic toxicology (Amsterdam, Netherlands) 20100801
An unusual stress metabolite induced by CuCl(2) and other constituents from the leaves of Chloranthus anhuiensis. Journal of natural products 20100625
Discovery of metabolic signatures for predicting whole organism toxicology. Toxicological sciences : an official journal of the Society of Toxicology 20100601
Antioxidant and electron donating function of hypothalamic polypeptides: galarmin and Gx-NH2. Neurochemical research 20100601
Stability of disubstituted copper complexes in the gas phase analyzed by electrospray ionization mass spectrometry. Rapid communications in mass spectrometry : RCM 20100515
Phenolic content and antioxidant activity of raspberry and blackberry cultivars. Journal of food science 20100501
Advanced glycation end products and antioxidant status in nondiabetic and streptozotocin induced diabetic rats: effects of copper treatment. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20100201
1,10-phenanthroline stabilizes mRNA of the carcinogen-metabolizing enzyme, cytochrome P450 1a1. Toxicology letters 20100201
Experimental study on the effects of H(2)O on PCDD/Fs formation by de novo synthesis in carbon/CuCl(2) model system. Chemosphere 20100201
A short, unsupported CuI...CuI interaction, 2.65 A, in a dinuclear guanidine chloride complex. Chemical communications (Cambridge, England) 20100107
An efficient, practical synthesis of 2-methoxyestradiol. Steroids 20100101
Type of cell death induced by seven metals in cultured mouse osteoblastic cells. In vivo (Athens, Greece) 20100101
Type of cell death induced by various metal cations in cultured human gingival fibroblasts. In vivo (Athens, Greece) 20100101
Efficient degradation of Rhodamine B by using ethylenediamine-CuCl2 complex under alkaline conditions. Journal of hazardous materials 20091115
Cu(II) complexes bearing the 2,2,2-tris(1-pyrazolyl)ethanol or 2,2,2-tris(1-pyrazolyl)ethyl methanesulfonate scorpionates. X-Ray structural characterization and application in the mild catalytic peroxidative oxidation of cyclohexane. Dalton transactions (Cambridge, England : 2003) 20091114
High-throughput cell-based screening of 4910 known drugs and drug-like small molecules identifies disulfiram as an inhibitor of prostate cancer cell growth. Clinical cancer research : an official journal of the American Association for Cancer Research 20091001
Changes in the protein expression profiles of the Hepa-T1 cell line when exposed to Cu2+. Aquatic toxicology (Amsterdam, Netherlands) 20090914
Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators. Journal of neurochemistry 20090901
Transcriptomic response of Argopecten purpuratus post-larvae to copper exposure under experimental conditions. Gene 20090801
Evaluation of toxic and interactive toxic effects of three agrochemicals and copper using a battery of microbiotests. The Science of the total environment 20090801
Gene expression profiling of copper-induced responses in the intertidal copepod Tigriopus japonicus using a 6K oligochip microarray. Aquatic toxicology (Amsterdam, Netherlands) 20090726
Study on a novel copper-containing composite for contraception. Contraception 20090601
Dominant roles of the polybasic proline motif and copper in the PrP23-89-mediated stress protection response. Journal of cell science 20090515
Cloning, expression, and characterization of cadmium-induced metallothionein-2 from the earthworms Metaphire posthuma and Polypheretima elongata. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090401
Cellular lipid metabolism is influenced by the coordination environment of copper. Journal of the American Chemical Society 20090225
CuX2-mediated halolactonization reaction of monoesters of 1,2-allenyl phosphonic acids and their Suzuki cross-coupling reaction. The Journal of organic chemistry 20090206
Metabolic acidosis increases intracellular calcium in bone cells through activation of the proton receptor OGR1. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090201
Metal ions-stimulated iron oxidation in hydroxylases facilitates stabilization of HIF-1 alpha protein. Toxicological sciences : an official journal of the Society of Toxicology 20090201
Binding-site mutations in the alpha1 subunit of the inhibitory glycine receptor convert the inhibitory metal ion Cu2+ into a positive modulator. Neuropharmacology 20090101
Novel mechanism for regulation of extracellular SOD transcription and activity by copper: role of antioxidant-1. Free radical biology & medicine 20090101
The mechanisms of oxidative DNA damage and apoptosis induced by norsalsolinol, an endogenous tetrahydroisoquinoline derivative associated with Parkinson's disease. Journal of neurochemistry 20090101
Regulation of heme synthesis and proteasomal activity by copper: possible implications for Wilson's disease. Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20090101
Synthesis and in vitro evaluation of the antifungal activities of dihydropyrimidinones. Bioorganic & medicinal chemistry letters 20081215
Transcriptional biomarkers and mechanisms of copper-induced olfactory injury in zebrafish. Environmental science & technology 20081215
Purification and biochemical characterization of methionine aminopeptidase (MetAP) from Mycobacterium smegmatis mc2155. Applied biochemistry and biotechnology 20081201
Homocysteine and copper interact to promote type 5 phosphodiesterase expression in rabbit cavernosal smooth muscle cells. Asian journal of andrology 20081101
Synthesis of beta-, gamma-, and delta-lactams via Pd(II)-catalyzed C-H activation reactions. Journal of the American Chemical Society 20081029
Accumulation of hypoxia-inducible factor-1 alpha protein and its role in the differentiation of myeloid leukemic cells induced by all-trans retinoic acid. Haematologica 20081001
Formation of hexachlorobenzene from dusts of an electric arc furnace used in steelmaking: effect of temperature and dust composition. Environmental science & technology 20081001
Enantiomeric reversed-phase high-performance liquid chromatography resolution of D-/L-penicillamine after spirocyclization with ninhydrin and by using copper(II)-L-proline complex as a chiral selector in the mobile phase. Journal of chromatography. A 20080926
Effects of exposure to multiple trace metals on biochemical, histological and ultrastructural features of gills of a freshwater fish, Channa punctata Bloch. Chemico-biological interactions 20080811
Copper ion-mediated liposomal encapsulation of mitoxantrone: the role of anions in drug loading, retention and release. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080807
Oxidative status of Matricaria chamomilla plants related to cadmium and copper uptake. Ecotoxicology (London, England) 20080801
Chlorination and thermal degradation of 2-chlorodibenzodioxin and dibenzofuran by CuCl2 or CuCl at 350 degrees C. Chemosphere 20080801
Direct synthesis of bicyclic guanidines through unprecedented palladium(ii) catalysed diamination with copper chloride as oxidant. Chemical communications (Cambridge, England) 20080528
Oxidative amination of cuprated pyrimidine and purine derivatives. Organic letters 20080501
Blocking creatine kinase refolding by trace amounts of copper ions. Journal of inorganic biochemistry 20080401
X-ray crystal structure and magnetic and photophysical properties of novel copper(II) N-oxide adduct [(4-MPyO)2(CuCl2)2(H2O)(C2H5OH)] (4-MPyO = 4-(4-methoxystyryl)pyridine N-oxide). Inorganic chemistry 20080317
Apoptosis of cultured astrocytes induced by the copper and neocuproine complex through oxidative stress and JNK activation. Toxicological sciences : an official journal of the Society of Toxicology 20080301
Imprinted polymers as drug delivery vehicles for metal-based anti-inflammatory drug. International journal of pharmaceutics 20080212
Efficient addition of alcohols, amines and phenol to unactivated alkenes by Au(III) or Pd(II) stabilized by CuCl2. Dalton transactions (Cambridge, England : 2003) 20080121
Cholinergic responses of ileal longitudinal muscle under short-lasting exposure to cupric ions. Autonomic & autacoid pharmacology 20080101
Prevention of oxidative DNA damage by bioactive berry components. Nutrition and cancer 20080101
Role of the epsilon subunit of thermophilic F1-ATPase as a sensor for ATP. The Journal of biological chemistry 20071228
BLT-1, a specific inhibitor of the HDL receptor SR-BI, induces a copper-dependent phenotype during zebrafish development. Toxicology letters 20071210
A simple and efficient procedure of low valent iron- or copper-mediated Reformatsky reaction of aldehydes. The Journal of organic chemistry 20071123
Synthesis of novel size exclusion chromatography support by surface initiated aqueous atom transfer radical polymerization. Langmuir : the ACS journal of surfaces and colloids 20071106
Molecular cloning and characterization of omega class glutathione S-transferase (GST-O) from the polychaete Neanthes succinea: biochemical comparison with theta class glutathione S-transferase (GST-T). Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20071101
A novel molecular assay to discriminate transcriptional effects caused by xenoestrogens. Molecular and cellular endocrinology 20070930
Molecular characterization of a transient expression gene encoding for 1-aminocyclopropane-1-carboxylate synthase in cotton (Gossypium hirsutum L.). Journal of biochemistry and molecular biology 20070930
Application of a biomarker battery for the evaluation of the sublethal effects of pollutants in the earthworm Eisenia andrei. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070901
Micro fluid segment technique for screening and development studies on Danio rerio embryos. Lab on a chip 20070901
Effect of copper on the cytotoxicity of phenanthrene and 9,10-phenanthrenequinone to the human placental cell line, JEG-3. Reproductive toxicology (Elmsford, N.Y.) 20070601
In vitro cytotoxicity assay with selected chemicals using human cells to predict target-organ toxicity of liver and kidney. Toxicology in vitro : an international journal published in association with BIBRA 20070601
Gene expression profiling of liver cells after copper overload in vivo and in vitro reveals new copper-regulated genes. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 20070501
Thermal degradation of 2-chlorophenol promoted by CuCl2 or CuCl: formation and destruction of PCDD/Fs. Chemosphere 20070401
Structural observations of time dependent oscillatory behavior of CuIICl2 solutions measured via extended X-ray absorption fine structure. Journal of inorganic biochemistry 20070401
[Visualization and evaluation of the promoter activities of genes for stress-inducible proteins in response to environmental pollutants]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20070401
CuCl-induced formation and migration of isoindazolyl carbenoids. The Journal of organic chemistry 20070330
Cu2+ and acute thermal stress induce protective events via the p38-MAPK signalling pathway in the perfused Rana ridibunda heart. The Journal of experimental biology 20070201
Purification and membrane reconstitution of catalytically active Menkes copper-transporting P-type ATPase (MNK; ATP7A). The Biochemical journal 20070115
RNA and CuCl2 induced conformational changes of the recombinant ovine prion protein. Molecular and cellular biochemistry 20070101
Effects of sulfur dioxide, hydrogen peroxide and sulfuric acid on the de novo synthesis of PCDD/F and PCB under model laboratory conditions. Chemosphere 20070101
Size matters! Fragmentation chemistry of [Cu(L)n]2+ complexes of diacylglycerophosphocholines as a function of coordination number (n = 2-7). Rapid communications in mass spectrometry : RCM 20070101
CuCl2-catalyzed one-pot formation of tetrahydroquinolines from N-methyl-N-alkylanilines and vinyl ethers in the presence of t-butylhydroperoxide. Molecules (Basel, Switzerland) 20061220
Hyaluronan degradation by copper(II) chloride and ascorbate: rotational viscometric, EPR spin-trapping, and MALDI-TOF mass spectrometric investigations. Carbohydrate research 20061211
Copper(I)-catalyzed chlorine atom transfer radical cyclization reactions of unsaturated alpha-chloro beta-keto esters. Organic letters 20061207
Novel supramolecular assembly of symmetrical mixed-metal-ligand complexes of dioxouranium(VI). Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20061201
Combination of NADPH and copper ions generates proteinase K-resistant aggregates from recombinant prion protein. The Journal of biological chemistry 20061117
Iron chelators reduce chromosomal breaks in ataxia-telangiectasia cells. DNA repair 20061108
Polychlorinated dibenzo-p-dioxin (PCDD) and dibenzofuran (PCDF) isomer patterns from municipal waste combustion: formation mechanism fingerprints. Chemosphere 20061101
Cadmium restores in vitro splicing activity inhibited by zinc-depletion. Archives of toxicology 20061001
Immunomodulation the marine green mussel Perna viridis exposed to sub-lethal concentrations of Cu and Hg. Archives of environmental contamination and toxicology 20061001
Expression profiling of endocrine-disrupting compounds using a customized Cyprinus carpio cDNA microarray. Toxicological sciences : an official journal of the Society of Toxicology 20061001
Products of Cu(II)-catalyzed oxidation of the N-terminal fragments of alpha-synuclein in the presence of hydrogen peroxide. Journal of inorganic biochemistry 20061001
Effect of water on catalyzed de novo formation of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans. Journal of hazardous materials 20060901
High affinity copper binding by stefin B (cystatin B) and its role in the inhibition of amyloid fibrillation. The FEBS journal 20060901
Properties of copper-free pig kidney amine oxidase: role of topa quinone. FEBS letters 20060807
Retinal localization and copper-dependent relocalization of the Wilson and Menkes disease proteins. Investigative ophthalmology & visual science 20060701
Mechanisms of the copper-dependent turnover of the copper chaperone for superoxide dismutase. The Journal of biological chemistry 20060512
Bioaccumulation of copper by Trichoderma viride. Bioresource technology 20060501
Crystal structures of triazine-3-thione derivatives by reaction with copper and cobalt salts. Inorganic chemistry 20060403
Variable reactivity of an engineered cysteine at position 338 in cystic fibrosis transmembrane conductance regulator reflects different chemical states of the thiol. The Journal of biological chemistry 20060324
Copper (II) ions potently inhibit purified PrPres amplification. Journal of neurochemistry 20060301
Soil properties affecting the toxicity of CuC12 and NiC12 for soil microbial processes in freshly spiked soils. Environmental toxicology and chemistry 20060301
Immuno-spin trapping of DNA radicals. Nature methods 20060201
Induction of cellular prion protein gene expression by copper in neurons. American journal of physiology. Cell physiology 20060101
Allergenicity and cross-reactivity of naphthenic acid and its metallic salts in experimental animals. Contact dermatitis 20060101
[Energy transformation coupled to formate oxidation during anaerobic fermentation]. Biofizika 20060101
Influence of copper on the interaction between cytochrome c and sulfite in vitro. Journal of biochemical and molecular toxicology 20060101
DNA damage in mouse lymphocytes exposed to curcumin and copper. Journal of applied genetics 20060101
The cupric ion reducing antioxidant capacity and polyphenolic content of some herbal teas. International journal of food sciences and nutrition 20060101
CuCl2-catalyzed PCDD/F formation and congener patterns from phenols. Chemosphere 20051201
Copper exposure induces trafficking of the menkes protein in intestinal epithelium of ATP7A transgenic mice. The Journal of nutrition 20051201
Acute thermal stress and various heavy metals induce tissue-specific pro- or anti-apoptotic events via the p38-MAPK signal transduction pathway in Mytilus galloprovincialis (Lam.). The Journal of experimental biology 20051201
Molecular mechanism of inhibition of nonclassical FGF-1 export. Biochemistry 20051129
Pathogenicity of Vibrio penaeicida for white shrimp Litopenaeus vannamei: a cysteine protease-like exotoxin as a virulence factor. Diseases of aquatic organisms 20051128
Interactions of charged ligands with beta(2)-microglobulin conformers in affinity capillary electrophoresis. Biochimica et biophysica acta 20051110
Oxidative dehydrogenation of dihydropyrimidinones and dihydropyrimidines. Organic letters 20051013
Physiological responses of Dunaliella salina and Dunaliella tertiolecta to copper toxicity. Biomolecular engineering 20051001
Extracellular histidine residues identify common structural determinants in the copper/zinc P2X2 receptor modulation. Journal of neurochemistry 20051001
Copper-dependent activation of hypoxia-inducible factor (HIF)-1: implications for ceruloplasmin regulation. Blood 20050615
Determination of total N-nitroso compounds by chemical denitrosation using CuCl. Journal of agricultural and food chemistry 20050615
Methionine regulates copper/hydrogen peroxide oxidation products of Abeta. Journal of peptide science : an official publication of the European Peptide Society 20050601
[Study on the structure of periodic and chaotic patterns of AMP-DC-Cu-gel systems]. Guang pu xue yu guang pu fen xi = Guang pu 20050601
Early-phase immunodetection of metallothionein and heat shock proteins in extruded earthworm coelomocytes after dermal exposure to metal ions. Environmental pollution (Barking, Essex : 1987) 20050501
Pyruvate protects motor neurons expressing mutant superoxide dismutase 1 against copper toxicity. Neuroreport 20050425
The characteristics of the (alpha V371C)3(beta R337C)3 gamma double mutant subcomplex of the TF1-ATPase indicate that the catalytic site at the alpha TP-beta TP interface with bound MgADP in crystal structures of MF1 represents a catalytic site containing inhibitory MgADP. Biochemistry 20050222
Active site rearrangement of the 2-hydrazinopyridine adduct in Escherichia coli amine oxidase to an azo copper(II) chelate form: a key role for tyrosine 369 in controlling the mobility of the TPQ-2HP adduct. Biochemistry 20050208
Quinone methide formations in the Cu(2+)-induced oxidation of a diterpenone catechol and concurrent damage on DNA. Chemical research in toxicology 20050201
Studies in oligonucleotide-based artificial nuclease systems. intramolecular copper (II) complex formation in an oligonucleotide bis-phenanthroline conjugate. Nucleosides, nucleotides & nucleic acids 20050101
Copper related toxic effects on cellular protein metabolism in human astrocytes. BioFactors (Oxford, England) 20050101
Stimulation of asiaticoside accumulation in the whole plant cultures of Centella asiatica (L.) urban by elicitors. Plant cell reports 20041101
Inhibition of the Escherichia coli RecA protein: zinc(II), copper(II) and mercury(II) trap RecA as inactive aggregates. Journal of inorganic biochemistry 20041101
Antioxidant properties of a novel phycocyanin extract from the blue-green alga Aphanizomenon flos-aquae. Life sciences 20040924
Furin inhibition by compounds of copper and zinc. The Journal of biological chemistry 20040827
Aerobic oxidation of 2,3,6-trimethylphenol to trimethyl-1,4-benzoquinone with copper(II) chloride as catalyst in ionic liquid and structure of the active species. Journal of the American Chemical Society 20040811
Effects of a fluoride etchant on resin bonding to titanium-aluminum-niobium alloy. European journal of oral sciences 20040801
Inner envelope protein 32 is imported into chloroplasts by a novel pathway. Journal of cell science 20040801
Inhibition by copper(II) binding of hepatocyte growth factor (HGF) interaction with its receptor Met and blockade of HGF/Met function. The Journal of biological chemistry 20040730
GammaM23K, gammaM232K, and gammaL77K single substitutions in the TF1-ATPase lower ATPase activity by disrupting a cluster of hydrophobic side chains. Biochemistry 20040727
Cloning of zebrafish metallothionein gene and characterization of its gene promoter region in HepG2 cell line. Biochimica et biophysica acta 20040713
Effects of copper source on phosphorus retention in broiler chicks and laying hens. Poultry science 20040601
Ligand-dependent structural changes in the V(1) ATPase from Manduca sexta. Journal of bioenergetics and biomembranes 20040601
Cu2+ toxicity inhibition of mitochondrial dehydrogenases in vitro and in vivo. Annals of neurology 20040501
Chloro(histamine)(1,10-phenanthroline)copper(II) chloride monohydrate. Acta crystallographica. Section C, Crystal structure communications 20040501
Efficacy of animal anti-fertility compounds against sea lamprey (Petromyzon marinus) spermatozoa. Theriogenology 20040415
Inducible superoxide dismutase 1 aggregation in transgenic amyotrophic lateral sclerosis mouse fibroblasts. Journal of cellular biochemistry 20040401
Organic copper complexes as a new class of proteasome inhibitors and apoptosis inducers in human cancer cells. Biochemical pharmacology 20040315
The ionic track in the F1-ATPase from the thermophilic Bacillus PS3. Biochemistry 20040309
Increase in the conformational flexibility of beta 2-microglobulin upon copper binding: a possible role for copper in dialysis-related amyloidosis. Protein science : a publication of the Protein Society 20040301
Metals accelerate production of the aberrant splicing isoform of the presenilin-2. Journal of neurochemistry 20040301
Effects of a metal etchant and two primers on resin bonding durability to titanium. European journal of oral sciences 20040201
Selenoprotein P protects low-density lipoprotein against oxidation. Free radical research 20040201
EPR, magnetic and spectral studies of copper(II) and nickel(II) complexes of schiff base macrocyclic ligand derived from thiosemicarbazide and glyoxal. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20040101
Quantitative changes of secondary metabolites of Matricaria chamomilla by abiotic stress. Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101
Phytoalexins from Thlaspi arvense, a wild crucifer resistant to virulent Leptosphaeria maculans: structures, syntheses and antifungal activity. Phytochemistry 20031101
Oxidative DNA damage induced by benz[a]anthracene metabolites via redox cycles of quinone and unique non-quinone. Chemical research in toxicology 20031101
Modulation of L-type voltage-gated calcium channels by recombinant prion protein. Journal of neurochemistry 20031101
Cu(II)-nitroxyl radicals as catalytic galactose oxidase mimics. Organic & biomolecular chemistry 20030921
Copper stimulates the synthesis and release of interleukin-8 in human endothelial cells: a possible early role in systemic inflammatory responses. Shock (Augusta, Ga.) 20030801
Chlorination of dibenzofuran and dibenzo-p-dioxin vapor by copper (II) chloride. Chemosphere 20030601
Effects of copper chloride on formation of polychlorinated dibenzo-p-dioxins in model waste incineration. Chemosphere 20030601
Estrogen-like activity of metals in MCF-7 breast cancer cells. Endocrinology 20030601
Oxidative demetalation of cyclohexadienyl ruthenium(II) complexes: a net Ru-mediated dearomatization. Organic letters 20030529
Inhibition of oxygen evolution in Photosystem II by Cu(II) ions is associated with oxidation of cytochrome b559. The Biochemical journal 20030415
Protective action of copper (II) complex of a Schiff base against DNA damage induced by m-chloroperbenzoic acid using a novel DNA unwinding technique. Journal of biochemical and biophysical methods 20030328
Overexpression of Arabidopsis phytochelatin synthase paradoxically leads to hypersensitivity to cadmium stress. Plant physiology 20030201
Modulatory effect of copper on nonenzymatic antioxidants in freshwater fish Channa punctatus (Bloch.). Biological trace element research 20030101
Effect of quercetin and genistein on copper- and iron-induced lipid peroxidation in methyl linolenate. Journal of applied toxicology : JAT 20030101
Dual effect of glucose on LDL oxidation: dependence on vitamin E. Free radical biology & medicine 20021015
Effects of copper on the expression of metal transporters in human intestinal Caco-2 cells. FEBS letters 20020911
Reactive oxygen species generated by PAH o-quinones cause change-in-function mutations in p53. Chemical research in toxicology 20020601
Cross-talk in the A1-ATPase from Methanosarcina mazei Go1 due to nucleotide binding. The Journal of biological chemistry 20020510
Effect of CuCl2, NaCl and EDTA on the enzyme alpha-L-iduronidase in the plasma of normal individuals and heterozygotes for MPS I. Clinica chimica acta; international journal of clinical chemistry 20020401
Copper inhibits activated protein C: protective effect of human albumin and an analogue of its high-affinity copper-binding site, d-DAHK. Biochemical and biophysical research communications 20020208
[L-Glutamate oxidase from Streptomyces cremeus 510 MGU: growth media optimization for the enhancement of the producer fermentative activity]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101
Copper modulation of extracellular matrix synthesis by human articular chondrocytes. Scandinavian journal of rheumatology 20020101
Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure. The Journal of biological chemistry 20011123
Spermidine as a potential biosynthetic precursor to the 1,5-diazabicyclo[4:3:o]nonene residue in the efrapeptins. The journal of peptide research : official journal of the American Peptide Society 20011101
CueO is a multi-copper oxidase that confers copper tolerance in Escherichia coli. Biochemical and biophysical research communications 20010907
Formation of polychlorinated dibenzo-p-dioxins/dibenzofurans from residual carbon on municipal solid waste incinerator fly ash using Na37Cl. Chemosphere 20010901
Copper stimulates human oral fibroblasts in vitro: a role in the pathogenesis of oral submucous fibrosis. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010901
Effects of metal salts on the oral production of volatile sulfur-containing compounds (VSC). Journal of clinical periodontology 20010801
Zinc enhances synthesis of presenilin 1 in mouse primary cortical culture. Biochemical and biophysical research communications 20010720
Antioxidant activity of amiodarone on human lipoprotein oxidation. British journal of pharmacology 20010701
Regioselective C-3-O-acylation and O-methylation of 4,6-O-benzylidene-beta-D-gluco- and galactopyranosides displaying a range of anomeric substituents. Carbohydrate research 20010518
Regio- and stereochemically controlled formation of hydroxamic acid containing anti- or syn-1,4-cycloalkenols from acylnitroso-derived Diels-Alder adducts. The Journal of organic chemistry 20010406
Induced accumulation of 2-hydroxy-4,7-dimethoxy-1,4-benzoxazin-3-one glucoside (HDMBOA-Glc) in maize leaves. Phytochemistry 20010401
Cu-metallothioneins (Cu(I)8-MTs) in LEC rat livers 13 weeks after birth still act as antioxidants. Archives of biochemistry and biophysics 20010315
Oxidative stress and c-Jun-amino-terminal kinase activation involved in apoptosis of primary astrocytes induced by disulfiram-Cu(2+) complex. European journal of pharmacology 20010302
Homocysteine potentiates copper- and amyloid beta peptide-mediated toxicity in primary neuronal cultures: possible risk factors in the Alzheimer's-type neurodegenerative pathways. Journal of neurochemistry 20010301
The Menkes copper transporter is required for the activation of tyrosinase. Human molecular genetics 20001122
The tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu2+ stimulates matrix metalloproteinase-2 expression by fibroblast cultures. Life sciences 20000922
Copper-transporting P-type adenosine triphosphatase (ATP7B) is associated with cisplatin resistance. Cancer research 20000301
Copper-dependent formation of disulfide-linked dimer of S100B protein. Archives of biochemistry and biophysics 20000215
Metal-induced modulation of nitric oxide production in vitro by murine macrophages: lead, nickel, and cobalt utilize different mechanisms. Toxicology and applied pharmacology 19961201
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