Cyanamide-mediated Inhibition of N-acetyltransferase 1.

Toxicology 20121208

Simultaneous high-performance liquid chromatography determination of coenzyme A, dephospho-coenzyme A, and acetyl-coenzyme A in normal and pantothenic acid-deficient rats.

Analytical biochemistry 20121115

Radical reactions of thiamin pyrophosphate in 2-oxoacid oxidoreductases.

Biochimica et biophysica acta 20121101

A detailed biochemical characterization of phosphopantothenate synthetase, a novel enzyme involved in coenzyme A biosynthesis in the Archaea.

Extremophiles : life under extreme conditions 20121101

Turnover-dependent covalent inactivation of Staphylococcus aureus coenzyme A-disulfide reductase by coenzyme A-mimetics: mechanistic and structural insights.

Biochemistry 20121002

Formation of a heterooctameric complex between aspartate α-decarboxylase and its cognate activating factor, PanZ, is CoA-dependent.

Biochemical and biophysical research communications 20120928

Stimulation of histone deacetylase activity by metabolites of intermediary metabolism.

The Journal of biological chemistry 20120914

The catalytic mechanism of the hotdog-fold enzyme superfamily 4-hydroxybenzoyl-CoA thioesterase from Arthrobacter sp. strain SU.

Biochemistry 20120904

Genetic studies of the role of fatty acid and coenzyme A in photocatalytic inactivation of Escherichia coli.

Water research 20120901

A selection platform for carbon chain elongation using the CoA-dependent pathway to produce linear higher alcohols.

Metabolic engineering 20120901

Impaired coenzyme A synthesis in fission yeast causes defective mitosis, quiescence-exit failure, histone hypoacetylation and fragile DNA.

Open biology 20120901

Coenzyme depletion by members of the aerolysin family of pore-forming toxins leads to diminished ATP levels and cell death.

Molecular bioSystems 20120801

Structural and biochemical characterization of a trapped coenzyme A adduct of Caenorhabditis elegans glucosamine-6-phosphate N-acetyltransferase 1.

Acta crystallographica. Section D, Biological crystallography 20120801

Taxol biosynthesis: tyrocidine synthetase A catalyzes the production of phenylisoserinyl CoA and other amino phenylpropanoyl thioesters.

Chemistry & biology 20120622

The antibiotic CJ-15,801 is an antimetabolite that hijacks and then inhibits CoA biosynthesis.

Chemistry & biology 20120525

Crystal structures of Xanthomonas campestris OleA reveal features that promote head-to-head condensation of two long-chain fatty acids.

Biochemistry 20120522

The missing link in coenzyme A biosynthesis: PanM (formerly YhhK), a yeast GCN5 acetyltransferase homologue triggers aspartate decarboxylase (PanD) maturation in Salmonella enterica.

Molecular microbiology 20120501

The human gene SLC25A17 encodes a peroxisomal transporter of coenzyme A, FAD and NAD+.

The Biochemical journal 20120401

Bacterial degradation of benzoate: cross-regulation between aerobic and anaerobic pathways.

The Journal of biological chemistry 20120323

Crystal structure of the complex between 4-hydroxybutyrate CoA-transferase from Clostridium aminobutyricum and CoA.

Archives of microbiology 20120301

Mitochondrial oxidative stress and epilepsy in SOD2 deficient mice: attenuation by a lipophilic metalloporphyrin.

Neurobiology of disease 20120301

Metabolic consequences of mitochondrial coenzyme A deficiency in patients with PANK2 mutations.

Molecular genetics and metabolism 20120301

A fluorescence-based assay for N-myristoyltransferase activity.

Analytical biochemistry 20120201

[The function of mitochondrion, carnitine, coenzyme-A, fat acids, glucose, the Randle cycle and insulin: a lecture].

Klinicheskaia laboratornaia diagnostika 20120201

Structural studies of AntD: an N-Acyltransferase involved in the biosynthesis of D-Anthrose.

Biochemistry 20120131

Investigation of the catalytic mechanism of the hotdog-fold enzyme superfamily Pseudomonas sp. strain CBS3 4-hydroxybenzoyl-CoA thioesterase.

Biochemistry 20120124

Diverse biological activities of the vascular non-inflammatory molecules - the Vanin pantetheinases.

Biochemical and biophysical research communications 20120113

An unanticipated architecture of the 750-kDa α6β6 holoenzyme of 3-methylcrotonyl-CoA carboxylase.

Nature 20120112

Acute pantothenic acid and cysteine supplementation does not affect muscle coenzyme A content, fuel selection, or exercise performance in healthy humans.

Journal of applied physiology (Bethesda, Md. : 1985) 20120101

Metformin rescues the myocardium from doxorubicin-induced energy starvation and mitochondrial damage in rats.

Oxidative medicine and cellular longevity 20120101

Substitution of asparagine 76 by a tyrosine residue induces domain swapping in Helicobacter pylori phosphopantetheine adenylyltransferase.

Journal of biomolecular structure & dynamics 20120101

An organic/inorganic hybrid membrane as a solid 'turn-on' fluorescent chemosensor for coenzyme A (CoA), cysteine (Cys), and glutathione (GSH) in aqueous media.

Sensors (Basel, Switzerland) 20120101

Germline deletion of pantothenate kinases 1 and 2 reveals the key roles for CoA in postnatal metabolism.

PloS one 20120101

Cofilin/Twinstar phosphorylation levels increase in response to impaired coenzyme a metabolism.

PloS one 20120101

Molecular mechanisms of ursodeoxycholic acid toxicity & side effects: ursodeoxycholic acid freezes regeneration & induces hibernation mode.

International journal of molecular sciences 20120101

The Bacillus anthracis arylamine N-acetyltransferase ((BACAN)NAT1) that inactivates sulfamethoxazole, reveals unusual structural features compared with the other NAT isoenzymes.

FEBS letters 20111215

Substrate recognition by β-ketoacyl-ACP synthases.

Biochemistry 20111213

SILEC: a protocol for generating and using isotopically labeled coenzyme A mass spectrometry standards.

Nature protocols 20111208

Coenzyme A binding to the aminoglycoside acetyltransferase (3)-IIIb increases conformational sampling of antibiotic binding site.

Biochemistry 20111206

Impaired Coenzyme A metabolism affects histone and tubulin acetylation in Drosophila and human cell models of pantothenate kinase associated neurodegeneration.

EMBO molecular medicine 20111201

Coenzyme A contained in mothers' milk is associated with the potential to induce atopic dermatitis.

International immunology 20111201

Crystal structure of phosphopantetheine adenylyltransferase from Enterococcus faecalis in the ligand-unbound state and in complex with ATP and pantetheine.

Molecules and cells 20111130

Vibrational coherence spectroscopy of the heme domain in the CO-sensing transcriptional activator CooA.

Journal of the American Chemical Society 20111123

Identifying developmental toxicity pathways for a subset of ToxCast chemicals using human embryonic stem cells and metabolomics.

Toxicology and applied pharmacology 20111115

Chemo-enzymatic synthesis of polyhydroxyalkanoate (PHA) incorporating 2-hydroxybutyrate by wild-type class I PHA synthase from Ralstonia eutropha.

Applied microbiology and biotechnology 20111101

Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but induce specific cancer cell death.

Pharmaceutical research 20111101

The coenzyme A disulphide reductase of Borrelia burgdorferi is important for rapid growth throughout the enzootic cycle and essential for infection of the mammalian host.

Molecular microbiology 20111101

Antibiotic selection by the promiscuous aminoglycoside acetyltransferase-(3)-IIIb is thermodynamically achieved through the control of solvent rearrangement.

Biochemistry 20111101

Enzymes involved in the anaerobic degradation of meta-substituted halobenzoates.

Molecular microbiology 20111101

Ligand-induced conformational changes within a hexameric Acyl-CoA thioesterase.

The Journal of biological chemistry 20111014

Identification of lysine acetyltransferase p300 substrates using 4-pentynoyl-coenzyme A and bioorthogonal proteomics.

Bioorganic & medicinal chemistry letters 20110901

Analysis of a range of catabolic mutants provides evidence that phytanoyl-coenzyme A does not act as a substrate of the electron-transfer flavoprotein/electron-transfer flavoprotein:ubiquinone oxidoreductase complex in Arabidopsis during dark-induced senescence.

Plant physiology 20110901

Substrate promiscuity of a rosmarinic acid synthase from lavender (Lavandula angustifolia L.).

Planta 20110801

Stabilization of the second oxyanion intermediate by 1,4-dihydroxy-2-naphthoyl-coenzyme A synthase of the menaquinone pathway: spectroscopic evidence of the involvement of a conserved aspartic acid.

Biochemistry 20110705

Methylmalonate-semialdehyde dehydrogenase from Bacillus subtilis: substrate specificity and coenzyme A binding.

The Journal of biological chemistry 20110624

Kinetics of inhibition of firefly luciferase by dehydroluciferyl-coenzyme A, dehydroluciferin and L-luciferin.

Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110601

Closing in on complete pathways of biotin biosynthesis.

Molecular bioSystems 20110601

Characterization of TioQ, a type II thioesterase from the thiocoraline biosynthetic cluster.

Molecular bioSystems 20110601

Characterization of non-enzymatic acylation of amino or thiol groups of bionucleophiles by the acyl-adenylate or acyl-CoA thioester of cholic acid.

Analytical and bioanalytical chemistry 20110601

Novel pathway for assimilation of dimethylsulphoniopropionate widespread in marine bacteria.

Nature 20110512

Structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase in complex with the feedback inhibitor CoA reveals only one active-site conformation.

Acta crystallographica. Section F, Structural biology and crystallization communications 20110501

Purification and characterization of OleA from Xanthomonas campestris and demonstration of a non-decarboxylative Claisen condensation reaction.

The Journal of biological chemistry 20110401

Studies on the mechanism of ring hydrolysis in phenylacetate degradation: a metabolic branching point.

The Journal of biological chemistry 20110401

Esterification of okadaic acid in the mussel Mytilus galloprovincialis.

Toxicon : official journal of the International Society on Toxinology 20110401

Aminoacyl-coenzyme A synthesis catalyzed by a CoA ligase from Penicillium chrysogenum.

FEBS letters 20110323

Structural and biochemical elucidation of mechanism for decarboxylative condensation of beta-keto acid by curcumin synthase.

The Journal of biological chemistry 20110225

Enzymatic extender unit generation for in vitro polyketide synthase reactions: structural and functional showcasing of Streptomyces coelicolor MatB.

Chemistry & biology 20110225

Stable isotope labeling by essential nutrients in cell culture for preparation of labeled coenzyme A and its thioesters.

Analytical chemistry 20110215

Influence of cellular arachidonic acid levels on phospholipid remodeling and CoA-independent transacylase activity in human monocytes and U937 cells.

Biochimica et biophysica acta 20110201

Maleimide photolithography for single-molecule protein-protein interaction analysis in micropatterns.

Analytical chemistry 20110115

New potent bisubstrate inhibitors of histone acetyltransferase p300: design, synthesis and biological evaluation.

Chemical biology & drug design 20110101

L-Carnitine attenuates ifosfamide-induced carnitine deficiency and decreased intramitochondrial CoA-SH in rat kidney tissues.

Journal of nephrology 20110101

The TIP30 protein complex, arachidonic acid and coenzyme A are required for vesicle membrane fusion.

PloS one 20110101

Insights into the regulatory characteristics of the mycobacterial dephosphocoenzyme A kinase: implications for the universal CoA biosynthesis pathway.

PloS one 20110101

A novel acyl-CoA beta-transaminase characterized from a metagenome.

PloS one 20110101

A novel N-acetylglutamate synthase architecture revealed by the crystal structure of the bifunctional enzyme from Maricaulis maris.

PloS one 20110101

Identification and characterization of oxalate oxidoreductase, a novel thiamine pyrophosphate-dependent 2-oxoacid oxidoreductase that enables anaerobic growth on oxalate.

The Journal of biological chemistry 20101224

Kinetic, thermodynamic, and structural insight into the mechanism of phosphopantetheine adenylyltransferase from Mycobacterium tuberculosis.

Journal of molecular biology 20101126

Characterization of 5-chloro-5-deoxy-D-ribose 1-dehydrogenase in chloroethylmalonyl coenzyme A biosynthesis: substrate and reaction profiling.

The Journal of biological chemistry 20101029

ATP-citrate lyase reduction mediates palmitate-induced apoptosis in pancreatic beta cells.

The Journal of biological chemistry 20101015

A general scheme for synthesis of substrate-based polyketide labels for acyl carrier proteins.

Bioorganic & medicinal chemistry letters 20101001

Michael acceptor-containing coenzyme A analogues as inhibitors of the atypical coenzyme A disulfide reductase from Staphylococcus aureus.

Journal of the American Chemical Society 20100922

Identification of the citrate-binding site of human ATP-citrate lyase using X-ray crystallography.

The Journal of biological chemistry 20100827

Modulation of pantothenate kinase 3 activity by small molecules that interact with the substrate/allosteric regulatory domain.

Chemistry & biology 20100827

Kinetic mechanism of the Rtt109-Vps75 histone acetyltransferase-chaperone complex.

Biochemistry 20100803

Coenzyme A-dependent aerobic metabolism of benzoate via epoxide formation.

The Journal of biological chemistry 20100702

Synthesis and characterization of cis-4-decenoyl-CoA, 3-phenylpropionyl-CoA, and 2,6-dimethylheptanoyl-CoA.

Analytical biochemistry 20100601

Pantothenate utilization by Plasmodium as a target for antimalarial chemotherapy.

Infectious disorders drug targets 20100601

Interactions of coenzyme A with the aminoglycoside acetyltransferase (3)-IIIb and thermodynamics of a ternary system.

Biochemistry 20100518

Three different and tissue-specific NAD-malic enzymes generated by alternative subunit association in Arabidopsis thaliana.

The Journal of biological chemistry 20100416

Mass spectrometric method incorporating enzymatic amplification for attomole-level analysis of target metabolites in biological samples.

Chemical communications (Cambridge, England) 20100407

5-Hydroxydecanoate and coenzyme A are inhibitors of native sarcolemmal KATP channels in inside-out patches.

Biochimica et biophysica acta 20100301

Functional immobilization and patterning of proteins by an enzymatic transfer reaction.

Analytical chemistry 20100215

Hyperoxia exposure alters hepatic eicosanoid metabolism in newborn mice.

Pediatric research 20100201

Alterations in brain glucose utilization accompanying elevations in blood ethanol and acetate concentrations in the rat.

Alcoholism, clinical and experimental research 20100201

Integrated network systems and evolutionary developmental endocrinology.

Medical hypotheses 20100101

Increased urinary losses of carnitine and decreased intramitochondrial coenzyme A in gentamicin-induced acute renal failure in rats.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20100101

Coenzyme A enhances activity of the mitochondrial adenine nucleotide translocator.

The international journal of biochemistry & cell biology 20100101

Computational study of the three-dimensional structure of N-acetyltransferase 2-acetyl coenzyme a complex.

Biological & pharmaceutical bulletin 20100101

Palmitate and insulin synergistically induce IL-6 expression in human monocytes.

Cardiovascular diabetology 20100101

Tissue-specific short chain fatty acid metabolism and slow metabolic recovery after ischemia from hyperpolarized NMR in vivo.

The Journal of biological chemistry 20091225

Cooperation between a coenzyme A-independent stand-alone initiation module and an iterative type I polyketide synthase during synthesis of mycobacterial phenolic glycolipids.

Journal of the American Chemical Society 20091125

The thiolase reaction mechanism: the importance of Asn316 and His348 for stabilizing the enolate intermediate of the Claisen condensation.

Biochemistry 20091124

Crystal structure and catalytic properties of Bacillus anthracis CoADR-RHD: implications for flavin-linked sulfur trafficking.

Biochemistry 20091013

Pantoate kinase and phosphopantothenate synthetase, two novel enzymes necessary for CoA biosynthesis in the Archaea.

The Journal of biological chemistry 20091009

Identification of domains involved in the allosteric regulation of cytosolic Arabidopsis thaliana NADP-malic enzymes.

The FEBS journal 20091001

Selective sensitization of cancer cells to DNA damage by a HAT inhibitor.

Cell cycle (Georgetown, Tex.) 20090915

The human malaria parasite Plasmodium falciparum is not dependent on host coenzyme A biosynthesis.

The Journal of biological chemistry 20090911

hChAT: a tool for the chemoenzymatic generation of potential acetyl/butyrylcholinesterase inhibitors.

Chembiochem : a European journal of chemical biology 20090904

In vitro precursor-directed synthesis of polyketide analogues with coenzyme a regeneration for the development of antiangiogenic agents.

Organic letters 20090903

Spermidinyl-CoA-based HAT inhibitors block DNA repair and provide cancer-specific chemo- and radiosensitization.

Cell cycle (Georgetown, Tex.) 20090901

Solid phase 4'-phosphopantetheinylation: fungal thiolation domains are targets for chemoenzymatic modification.

Bioconjugate chemistry 20090819

Multimeric options for the auto-activation of the Saccharomyces cerevisiae FAS type I megasynthase.

Structure (London, England : 1993) 20090812

Current medical aspects of pantethine.

Ideggyogyaszati szemle 20090730

A novel member of solute carrier family 25 (SLC25A42) is a transporter of coenzyme A and adenosine 3',5'-diphosphate in human mitochondria.

The Journal of biological chemistry 20090703

The Pseudomonas aeruginosa liuE gene encodes the 3-hydroxy-3-methylglutaryl coenzyme A lyase, involved in leucine and acyclic terpene catabolism.

FEMS microbiology letters 20090701

Preparation, characterization and drug release behavior of polyion complex micelles.

International journal of pharmaceutics 20090605

Structural snapshots for the conformation-dependent catalysis by human medium-chain acyl-coenzyme A synthetase ACSM2A.

Journal of molecular biology 20090522

Genetic analysis of coenzyme A biosynthesis in the yeast Saccharomyces cerevisiae: identification of a conditional mutation in the pantothenate kinase gene CAB1.

Current genetics 20090401

Mycobacterium tuberculosis pantothenate kinase: possible changes in location of ligands during enzyme action.

Acta crystallographica. Section D, Biological crystallography 20090401

Biochemical and physiological characterization of Arabidopsis thaliana AtCoAse: a Nudix CoA hydrolyzing protein that improves plant development.

Physiologia plantarum 20090401

Detection of metabolite changes in C6 glioma cells cultured with antimitotic oleyl glycoside by 1H MAS NMR.

Journal of medicinal chemistry 20090312

Temperature stability of proteins essential for the intracellular survival of Mycobacterium tuberculosis.

The Biochemical journal 20090301

Identification of the lysine residue responsible for coenzyme A binding in the heterodimeric 2-oxoacid:ferredoxin oxidoreductase from Sulfolobus tokodaii, a thermoacidophilic archaeon, using 4-fluoro-7-nitrobenzofurazan as an affinity label.

Biochimica et biophysica acta 20090201

Phylogenetic analysis, homology modelling, molecular dynamics and docking studies of caffeoyl-CoA-O- methyl transferase (CCoAOMT 1 and 2) isoforms isolated from subabul (Leucaena leucocephala).

Journal of molecular modeling 20090201

Bisubstrate Inhibitors of the MYST HATs Esa1 and Tip60.

Bioorganic & medicinal chemistry 20090201

Preparation and drug controlled-release of polyion complex micelles as drug delivery systems.

Colloids and surfaces. B, Biointerfaces 20090201

[A look into the Archaeal genomes].

Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20090201

Comparative study of sesame lignans (sesamin, episesamin and sesamolin) affecting gene expression profile and fatty acid oxidation in rat liver.

Journal of nutritional science and vitaminology 20090201

Structural characterization of CalO2: a putative orsellinic acid P450 oxidase in the calicheamicin biosynthetic pathway.

Proteins 20090101

Synthesis of a phosphonate-linked aminoglycoside-coenzyme a bisubstrate and use in mechanistic studies of an enzyme involved in aminoglycoside resistance.

Chemistry (Weinheim an der Bergstrasse, Germany) 20090101

Chapter 10 using phosphopantetheinyl transferases for enzyme posttranslational activation, site specific protein labeling and identification of natural product biosynthetic gene clusters from bacterial genomes.

Methods in enzymology 20090101

Overexpression and characterization of medium-chain-length polyhydroxyalkanoate granule bound polymerases from Pseudomonas putida GPo1.

Microbial cell factories 20090101

Identification of marker genes for lipid-lowering effect of a short-chain fructooligosaccharide by DNA microarray analysis.

Journal of dietary supplements 20090101

Development of a method for the parallel synthesis and purification of N-substituted pantothenamides, known inhibitors of coenzyme A biosynthesis and utilization.

Organic & biomolecular chemistry 20081207

Control of lipid oxidation during exercise: role of energy state and mitochondrial factors.

Acta physiologica (Oxford, England) 20081201

Structure of an acetyl-CoA binding protein from Staphylococcus aureus representing a novel subfamily of GCN5-related N-acetyltransferase-like proteins.

Journal of structural and functional genomics 20081201

The sulfur atoms of the substrate CoA and the catalytic cysteine are required for a productive mode of substrate binding in bacterial biosynthetic thiolase, a thioester-dependent enzyme.

The FEBS journal 20081201

Bacillus anthracis o-succinylbenzoyl-CoA synthetase: reaction kinetics and a novel inhibitor mimicking its reaction intermediate.

Biochemistry 20081125

Antibiotic evaluation and in vivo analysis of alkynyl Coenzyme A antimetabolites in Escherichia coli.

Bioorganic & medicinal chemistry letters 20081115

The biochemistry of drug metabolism--an introduction: part 4. reactions of conjugation and their enzymes.

Chemistry & biodiversity 20081101

Pyruvate uptake is inhibited by valproic acid and metabolites in mitochondrial membranes.

FEBS letters 20081015

Synthesis and use of sulfonamide-, sulfoxide-, or sulfone-containing aminoglycoside-CoA bisubstrates as mechanistic probes for aminoglycoside N-6'-acetyltransferase.

Bioorganic & medicinal chemistry letters 20081015

L-Carnitine suppresses oleic acid-induced membrane permeability transition of mitochondria.

Cell biochemistry and function 20081001

Effect of energy compound on skeletal muscle strain injury and regeneration in rats.

Industrial health 20081001

Direct site-selective covalent protein immobilization catalyzed by a phosphopantetheinyl transferase.

Journal of the American Chemical Society 20080917

Structural characterization of a 140 degrees domain movement in the two-step reaction catalyzed by 4-chlorobenzoate:CoA ligase.

Biochemistry 20080805

Mechanism of 4-chlorobenzoate:coenzyme a ligase catalysis.

Biochemistry 20080805

An eight residue fragment of an acyl carrier protein suffices for post-translational introduction of fluorescent pantetheinyl arms in protein modification in vitro and in vivo.

Journal of the American Chemical Society 20080730

Role of betaine:CoA ligase (CaiC) in the activation of betaines and the transfer of coenzyme A in Escherichia coli.

Journal of applied microbiology 20080701

De novo CoA biosynthesis is required to maintain DNA integrity during development of the Drosophila nervous system.

Human molecular genetics 20080701

An optimized luciferase bioluminescent assay for coenzyme A.

Analytical and bioanalytical chemistry 20080701

A shared binding site for NAD+ and coenzyme A in an acetaldehyde dehydrogenase involved in bacterial degradation of aromatic compounds.

Biochemistry 20080701

Malonyl CoenzymeA decarboxylase regulates lipid and glucose metabolism in human skeletal muscle.

Diabetes 20080601

An orthogonal purification strategy for isolating crosslinked domains of modular synthases.

Bioorganic & medicinal chemistry letters 20080515

Pyridine nucleotide complexes with Bacillus anthracis coenzyme A-disulfide reductase: a structural analysis of dual NAD(P)H specificity.

Biochemistry 20080506

Structure of a putative acetyltransferase (PA1377) from Pseudomonas aeruginosa.

Acta crystallographica. Section F, Structural biology and crystallization communications 20080501

Divergence of function in the hot dog fold enzyme superfamily: the bacterial thioesterase YciA.

Biochemistry 20080304

Modulation of hSlo BK current inactivation by fatty acid esters of CoA.

Journal of neurochemistry 20080301

Acyl derivatives of coenzyme A inhibit platelet function via antagonism at P2Y1 and P2Y12 receptors: a new finding that may influence the design of anti-thrombotic agents.

Platelets 20080301

Interaction of the electrophilic ketoprofenyl-glucuronide and ketoprofenyl-coenzyme A conjugates with cytosolic glutathione S-transferases.

Drug metabolism and disposition: the biological fate of chemicals 20080201

Structural and functional characterization of the TRI101 trichothecene 3-O-acetyltransferase from Fusarium sporotrichioides and Fusarium graminearum: kinetic insights to combating Fusarium head blight.

The Journal of biological chemistry 20080118

Divergence of cofactor recognition across evolution: coenzyme A binding in a prokaryotic arylamine N-acetyltransferase.

Journal of molecular biology 20080104

Coenzyme A biosynthesis: an antimicrobial drug target.

FEMS microbiology reviews 20080101

Influence of the plant extract complex 'AdMax' on global gene expression levels in cultured human fibroblasts.

Journal of dietary supplements 20080101

Preparation and properties of a pH/temperature-responsive carboxymethyl chitosan/poly(N-isopropylacrylamide)semi-IPN hydrogel for oral delivery of drugs.

Carbohydrate research 20071126

Mechanism and substrate recognition of human holo ACP synthase.

Chemistry & biology 20071126

How pantothenol intervenes in Coenzyme-A biosynthesis of Mycobacterium tuberculosis.

Biochemical and biophysical research communications 20071005

Stable expression of the oxc and frc genes from Oxalobacter formigenes in human embryo kidney 293 cells: implications for gene therapy of hyperoxaluria.

International journal of molecular medicine 20071001

Identification of the cysteine residue exposed by the conformational change in pig heart succinyl-CoA:3-ketoacid coenzyme A transferase on binding coenzyme A.

Biochemistry 20070925

Peroxisomes contain a specific phytanoyl-CoA/pristanoyl-CoA thioesterase acting as a novel auxiliary enzyme in alpha- and beta-oxidation of methyl-branched fatty acids in mouse.

The Journal of biological chemistry 20070914

Analysis of intracellular short organic acid-coenzyme A esters from actinomycetes using liquid chromatography-electrospray ionization-mass spectrometry.

Journal of mass spectrometry : JMS 20070901

Feedback inhibition of pantothenate kinase regulates pantothenol uptake by the malaria parasite.

The Journal of biological chemistry 20070831

Discovery and characterization of a second mammalian thiol dioxygenase, cysteamine dioxygenase.

The Journal of biological chemistry 20070831

Domain architecture of pyruvate carboxylase, a biotin-dependent multifunctional enzyme.

Science (New York, N.Y.) 20070824

Transient kinetic studies support refinements to the chemical and kinetic mechanisms of aminolevulinate synthase.

The Journal of biological chemistry 20070810

Preparation and characterization of temperature and pH-sensitive chitosan material and its controlled release on coenzyme A.

Colloids and surfaces. B, Biointerfaces 20070801

Biochemical characterization of enoyl reductase involved in Type II fatty acid synthesis in the intestinal coccidium Eimeria tenella (Phylum Apicomplexa).

FEMS microbiology letters 20070701

Crystallographic snapshots of oxalyl-CoA decarboxylase give insights into catalysis by nonoxidative ThDP-dependent decarboxylases.

Structure (London, England : 1993) 20070701

Characterization of NcsB2 as a promiscuous naphthoic acid/coenzyme A ligase integral to the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin.

Journal of the American Chemical Society 20070627

Formation of an enolate intermediate is required for the reaction catalyzed by 3-hydroxyacyl-CoA dehydrogenase.

Bioorganic & medicinal chemistry letters 20070601

Structural and mutational studies of anthocyanin malonyltransferases establish the features of BAHD enzyme catalysis.

The Journal of biological chemistry 20070525

Structural basis for cofactor-independent dioxygenation in vancomycin biosynthesis.

Nature 20070517

Preparation and characterization of pH sensitive comb-shaped chitosan material for the controlled release of coenzyme A.

Journal of materials science. Materials in medicine 20070501

A new spectrofluorometric probe for the determination of trace amounts of CoA in injection, human serum and pig livers.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070501

Crystallographic and kinetic studies of human mitochondrial acetoacetyl-CoA thiolase: the importance of potassium and chloride ions for its structure and function.

Biochemistry 20070410

Studies on the extra-mitochondrial CoA -ester formation of valproic and Delta4 -valproic acids.

Biochimica et biophysica acta 20070401

Structure of the type III pantothenate kinase from Bacillus anthracis at 2.0 A resolution: implications for coenzyme A-dependent redox biology.

Biochemistry 20070320

Spectrofluorimetric determination of trace amounts of coenzyme A using a terbium ion-ciprofloxacin complex probe in the presence of periodic acid.

Analytical and bioanalytical chemistry 20070301

Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis.

Chemistry & biology 20070301

Microbial transformation of ferulic acid to vanillic acid by Streptomyces sannanensis MTCC 6637.

Journal of industrial microbiology & biotechnology 20070201

Irreversible inhibition of glucose-6-phosphate dehydrogenase by the coenzyme A conjugate of ketoprofen: a key to oxidative stress induced by non-steroidal anti-inflammatory drugs?

Biochemical pharmacology 20070201

One-pot preparation of coenzyme A analogues via an improved chemo-enzymatic synthesis of pre-CoA thioester synthons.

Chemical communications (Cambridge, England) 20070128

Novel sulfamide analogs of oleoylethanolamide showing in vivo satiety inducing actions and PPARalpha activation.

Journal of medicinal chemistry 20070125

Reversible covalent inhibition of a phenol sulfotransferase by coenzyme A.

Archives of biochemistry and biophysics 20070115

Structural characterization of a beta-diketone hydrolase from the cyanobacterium Anabaena sp. PCC 7120 in native and product-bound forms, a coenzyme A-independent member of the crotonase suprafamily.

Biochemistry 20070109

High-throughput system for analyzing ligand-induced cofactor recruitment by vitamin D receptor.

Bioconjugate chemistry 20070101

Novel CoA-polyamine conjugates for effective inhibition of spermine/spermidine-N1-acetyltransferase.

Nucleosides, nucleotides & nucleic acids 20070101

Substrate binding and catalytic mechanism of human choline acetyltransferase.

Biochemistry 20061212

Peroxisomal membrane permeability and solute transfer.

Biochimica et biophysica acta 20061201

The inside tag.

Nature methods 20061101

Structure of coenzyme A-disulfide reductase from Staphylococcus aureus at 1.54 A resolution.

Biochemistry 20060926

Characterization of the acyl substrate binding pocket of acetyl-CoA synthetase.

Biochemistry 20060926

Synthesis and evaluation of bioorthogonal pantetheine analogues for in vivo protein modification.

Journal of the American Chemical Society 20060920

Simultaneous quantitative analysis of metabolites using ion-pair liquid chromatography-electrospray ionization mass spectrometry.

Analytical chemistry 20060915

Simultaneous species identification and detection of methicillin resistance in staphylococci using triplex real-time PCR assay.

Diagnostic microbiology and infectious disease 20060901

Cytoplasmic accumulation of long-chain coenzyme A esters activates KATP and inhibits Kir2.1 channels.

The Journal of physiology 20060901

Endogenous coenzyme A glutathione disulfide in human myocardial tissue.

Journal of endocrinological investigation 20060901

Purification and characterization of enzyme responsible for N-myristoylation of octapeptide in aqueous solution without ATP and coenzyme a from Pseudomonas aeruginosa.

Journal of bioscience and bioengineering 20060901

The product complex of M. tuberculosis malate synthase revisited.

Protein science : a publication of the Protein Society 20060801

A type III polyketide synthase from Wachendorfia thyrsiflora and its role in diarylheptanoid and phenylphenalenone biosynthesis.

Planta 20060701

Plant coenzyme A biosynthesis: characterization of two pantothenate kinases from Arabidopsis.

Plant molecular biology 20060701

Analysis of the temperature-sensitive mutation of Escherichia coli pantothenate kinase reveals YbjN as a possible protein stabilizer.

Biochemical and biophysical research communications 20060630

Brain pyruvate and 2-oxoglutarate dehydrogenase complexes are mitochondrial targets of the CoA ester of the Refsum disease marker phytanic acid.

FEBS letters 20060612

The vasodilator potency of the endothelium-derived relaxing factor, L-S-nitrosocysteine, is impaired in conscious spontaneously hypertensive rats.

Vascular pharmacology 20060601

Invariance and variability in bacterial PanK: a study based on the crystal structure of Mycobacterium tuberculosis PanK.

Acta crystallographica. Section D, Biological crystallography 20060601

Peroxisomal trans-2-enoyl-CoA reductase is involved in phytol degradation.

FEBS letters 20060403

A monotopic membrane protein goes solo.

Structure (London, England : 1993) 20060401

Chronic carbamazepine decreases the incorporation rate and turnover of arachidonic acid but not docosahexaenoic acid in brain phospholipids of the unanesthetized rat: relevance to bipolar disorder.

Biological psychiatry 20060301

An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment.

Plant physiology 20060301

Priming type II polyketide synthases via a type II nonribosomal peptide synthetase mechanism.

Journal of the American Chemical Society 20060208

The substrate-induced conformational change of Mycobacterium tuberculosis mycothiol synthase.

The Journal of biological chemistry 20060203

Seizure-induced changes in mitochondrial redox status.

Free radical biology & medicine 20060115

One-pot chemo-enzymatic synthesis of reporter-modified proteins.

Organic & biomolecular chemistry 20060107

Acute effect of fatty acids on metabolism and mitochondrial coupling in skeletal muscle.

Biochimica et biophysica acta 20060101

Borrelia burgdorferi bb0728 encodes a coenzyme A disulphide reductase whose function suggests a role in intracellular redox and the oxidative stress response.

Molecular microbiology 20060101

Chemical expansion of cofactor activity.

Nature chemical biology 20060101

Crystallographic trapping of the glutamyl-CoA thioester intermediate of family I CoA transferases.

The Journal of biological chemistry 20051230

Structure of human phytanoyl-CoA 2-hydroxylase identifies molecular mechanisms of Refsum disease.

The Journal of biological chemistry 20051209

Crystal structures of a phosphotransacetylase from Bacillus subtilis and its complex with acetyl phosphate.

Journal of structural and functional genomics 20051201

The identification of a succinyl-CoA thioesterase suggests a novel pathway for succinate production in peroxisomes.

The Journal of biological chemistry 20051118

Trichloroacetic acid-facilitated coenzyme A-SH-stabilization-based end-point spectrophotometric 5,5'-dithiobis-2-nitrobenzoic acid assay for plant terpene alcohol acetyltransferases.

Analytical biochemistry 20051101

Chemoenzymatic approaches for streamlined detection of active site modifications on thiotemplate assembly lines using mass spectrometry.

Biochemistry 20051101

Coenzyme A affects firefly luciferase luminescence because it acts as a substrate and not as an allosteric effector.

The FEBS journal 20051001

Feedback regulation of murine pantothenate kinase 3 by coenzyme A and coenzyme A thioesters.

The Journal of biological chemistry 20050923

Free CoA-mediated regulation of intermediary and central metabolism: an hypothesis which accounts for the excretion of alpha-ketoglutarate during aerobic growth of Escherichia coli on acetate.

Research in microbiology 20050901

In vivo reporter labeling of proteins via metabolic delivery of coenzyme A analogues.

Journal of the American Chemical Society 20050817

Fluorescence analysis of a dynamic loop in the PCAF/GCN5 histone acetyltransferase.

Biochemistry 20050809

Characterization of the final step in the conversion of phytol into phytanic acid.

The Journal of biological chemistry 20050722

Mitochondrial glycerol-3-phosphate acyltransferase-1 is essential in liver for the metabolism of excess acyl-CoAs.

The Journal of biological chemistry 20050708

Long-chain acyl-CoA esters inhibit phosphorylation of AMP-activated protein kinase at threonine-172 by LKB1/STRAD/MO25.

American journal of physiology. Endocrinology and metabolism 20050601

Constitutive UCP3 overexpression at physiological levels increases mouse skeletal muscle capacity for fatty acid transport and oxidation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050601

Characterization of a new pantothenate kinase isoform from Helicobacter pylori.

The Journal of biological chemistry 20050527

The diverse phenotype and genotype of pantothenate kinase-associated neurodegeneration.

Neurology 20050524

Peroxisome proliferator-activated receptor alpha interacts with high affinity and is conformationally responsive to endogenous ligands.

The Journal of biological chemistry 20050513

Pantothenic acid quantification: method comparison of a stable isotope dilution assay and a microbiological assay.

International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20050501

Iso-coenzyme A.

The Journal of biological chemistry 20050429

A yeast polyamine acetyltransferase.

The Journal of biological chemistry 20050429

Crystal structure of Escherichia coli crotonobetainyl-CoA: carnitine CoA-transferase (CaiB) and its complexes with CoA and carnitinyl-CoA.

Biochemistry 20050419

Crystal structure of vinorine synthase, the first representative of the BAHD superfamily.

The Journal of biological chemistry 20050408

Unidirectional inversion of ibuprofen in Caco-2 cells: developing a suitable model for presystemic chiral inversion study.

Biological & pharmaceutical bulletin 20050401

Breakdown of 2-hydroxylated straight chain fatty acids via peroxisomal 2-hydroxyphytanoyl-CoA lyase: a revised pathway for the alpha-oxidation of straight chain fatty acids.

The Journal of biological chemistry 20050318

High resolution crystal structures of human cytosolic thiolase (CT): a comparison of the active sites of human CT, bacterial thiolase, and bacterial KAS I.

Journal of molecular biology 20050318

Discovery and characterization of a Coenzyme A disulfide reductase from Pyrococcus horikoshii. Implications for this disulfide metabolism of anaerobic hyperthermophiles.

The FEBS journal 20050301

Homology modeling and PAPS ligand (cofactor) binding study of bovine phenol sulfotransferase.

Journal of molecular modeling 20050301

Substrate specificities of Escherichia coli thioesterase I/protease I/lysophospholipase L1 are governed by its switch loop movement.

Biochemistry 20050215

Mutagenesis evidence that the partial reactions of firefly bioluminescence are catalyzed by different conformations of the luciferase C-terminal domain.

Biochemistry 20050208

A pantothenate kinase from Staphylococcus aureus refractory to feedback regulation by coenzyme A.

The Journal of biological chemistry 20050204

The selectivity for cysteine over serine in coenzyme A biosynthesis.

Chembiochem : a European journal of chemical biology 20050201

Altered neuronal mitochondrial coenzyme A synthesis in neurodegeneration with brain iron accumulation caused by abnormal processing, stability, and catalytic activity of mutant pantothenate kinase 2.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20050119

5-Hydroxydecanoate is metabolised in mitochondria and creates a rate-limiting bottleneck for beta-oxidation of fatty acids.

The Journal of physiology 20050115

Coenzyme A: back in action.

Progress in lipid research 20050101

Neurodegeneration with brain iron accumulation.

Folia neuropathologica 20050101

In vitro biosynthesis of glycosylphosphatidylinositol in Aspergillus fumigatus.

Biochemistry 20041207

Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites.

The Journal of biological chemistry 20041203

Age-related compensatory activation of pyruvate dehydrogenase complex in rat heart.

Biochemical and biophysical research communications 20041203

Purification, crystallization and preliminary X-ray crystallographic analysis of hydroxycinnamoyl-coenzyme A hydratase-lyase (HCHL), a crotonase homologue active in phenylpropanoid metabolism.

Acta crystallographica. Section D, Biological crystallography 20041201

[Pantothenic acid].

Nihon rinsho. Japanese journal of clinical medicine 20041201

Structural insights and functional implications of choline acetyltransferase.

Journal of structural biology 20041101

The rat liver peroxisomal membrane forms a permeability barrier for cofactors but not for small metabolites in vitro.

Journal of cell science 20041101

Structural basis of CTP-dependent peptide bond formation in coenzyme A biosynthesis catalyzed by Escherichia coli PPC synthetase.

Structure (London, England : 1993) 20041101

Structure and function of carnitine acyltransferases.

Annals of the New York Academy of Sciences 20041101

Interaction between altered insulin and lipid metabolism in CEACAM1-inactive transgenic mice.

The Journal of biological chemistry 20041022

Infantile neuroaxonal dystrophy and pantothenate-kinase-associated neurodegeneration: locus heterogeneity.

Neurology 20040914

Initiation of surfactin biosynthesis and the role of the SrfD-thioesterase protein.

Biochemistry 20040907

Determination of long-chain fatty acid acyl-coenzyme A compounds using liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040905

Substrate-induced asymmetry and channel closure revealed by the apoenzyme structure of Mycobacterium tuberculosis phosphopantetheine adenylyltransferase.

Protein science : a publication of the Protein Society 20040901

Flux to acetate and lactate excretions in industrial fermentations: physiological and biochemical implications.

Journal of industrial microbiology & biotechnology 20040801

Specific labeling of cell surface proteins with chemically diverse compounds.

Journal of the American Chemical Society 20040728

Fatty acyl CoA-mediated inhibition of endoplasmic reticulum assembly.

Biochimica et biophysica acta 20040723

Coenzyme A biosynthesis: reconstruction of the pathway in archaea and an evolutionary scenario based on comparative genomics.

Molecular biology and evolution 20040701

Effects of a novel dual lipid synthesis inhibitor and its potential utility in treating dyslipidemia and metabolic syndrome.

Journal of lipid research 20040701

Bisubstrate analogue structure-activity relationships for p300 histone acetyltransferase inhibitors.

Bioorganic & medicinal chemistry 20040615

Biochemical demonstration of the involvement of fatty acyl-CoA synthetase in fatty acid translocation across the plasma membrane.

The Journal of biological chemistry 20040604

Structure of serine acetyltransferase in complexes with CoA and its cysteine feedback inhibitor.

Biochemistry 20040525

Discovery and directed evolution of a glyphosate tolerance gene.

Science (New York, N.Y.) 20040521

Choline acetyltransferase structure reveals distribution of mutations that cause motor disorders.

The EMBO journal 20040519

Direct desaturation of free myristic acid by hen liver microsomal Delta9-desaturase without prior activation to myristoyl-CoA derivative.

Journal of agricultural and food chemistry 20040519

Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal.

The Biochemical journal 20040501

A sensitive and robust method for quantification of intracellular short-chain coenzyme A esters.

Analytical biochemistry 20040501

Structure-based mutational analysis of the 4'-phosphopantetheinyl transferases Sfp from Bacillus subtilis: carrier protein recognition and reaction mechanism.

Biochemistry 20040413

Cofactor engineering of intracellular CoA/acetyl-CoA and its effect on metabolic flux redistribution in Escherichia coli.

Metabolic engineering 20040401

Chemo- and regioselective peptide cyclization triggered by the N-terminal fatty acid chain length: the recombinant cyclase of the calcium-dependent antibiotic from Streptomyces coelicolor.

Biochemistry 20040316

Stabilization and characterization of histidine-tagged homocitrate synthase from Saccharomyces cerevisiae.

Archives of biochemistry and biophysics 20040115

The SNARE Ykt6 mediates protein palmitoylation during an early stage of homotypic vacuole fusion.

The EMBO journal 20040114

Identification of luciferyl adenylate and luciferyl coenzyme a synthesized by firefly luciferase.

Chembiochem : a European journal of chemical biology 20040103

Propionyl-coenzyme A synthetases of Ralstonia solanacearum and Salmonella choleraesuis display atypical kinetics.

FEBS letters 20040102

PPARalpha controls the intracellular coenzyme A concentration via regulation of PANK1alpha gene expression.

Journal of lipid research 20040101

One-pot chemoenzymatic preparation of coenzyme A analogues.

Analytical biochemistry 20040101

Serotonin metabolism in rat skin: characterization by liquid chromatography-mass spectrometry.

Archives of biochemistry and biophysics 20040101

New substrate analogues of human serotonin N-acetyltransferase produce in situ specific and potent inhibitors.

European journal of biochemistry 20040101

Inhibition of hepatocyte lipogenesis by nitric oxide donor: could nitric oxide regulate lipid synthesis?

IUBMB life 20040101

Systemic lupus erythematosus: a combined deficiency disease.

Medical hypotheses 20040101

Enhanced isoamyl acetate production upon manipulation of the acetyl-CoA node in Escherichia coli.

Biotechnology progress 20040101

Supplementation of L-carnitine in athletes: does it make sense?

Nutrition (Burbank, Los Angeles County, Calif.) 20040101

Carnitine acyltransferases and their influence on CoA pools in health and disease.

Molecular aspects of medicine 20040101

[Coenzyme A biosynthesis as universal mechanism of conjugation of exogenous and multiple pantothenic acid functions].

Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20040101

Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates.

Biochemistry 20031216

Further studies on the substrate spectrum of phytanoyl-CoA hydroxylase: implications for Refsum disease?

Journal of lipid research 20031201

Divergent effects of eicosapentaenoic and docosahexaenoic acid ethyl esters, and fish oil on hepatic fatty acid oxidation in the rat.

Biochimica et biophysica acta 20031130

Use of novel assays to indicate that O-esters and S-esters are produced by the same enzyme in brewing yeast.

FEMS microbiology letters 20031107

Production of vancomycin aglycone conjugated to a peptide carrier domain derived from a biosynthetic non-ribosomal peptide synthetase.

Chemical communications (Cambridge, England) 20031107

Single-sample preparation for simultaneous cellular redox and energy state determination.

Analytical biochemistry 20031101

4'-phosphopantetheine and coenzyme A biosynthesis in plants.

The Journal of biological chemistry 20031003

Novel bisubstrate analog inhibitors of serotonin N-acetyltransferase: the importance of being neutral.

Bioorganic chemistry 20031001

Polyhydroxyalkanoate (PHA) hemeostasis: the role of PHA synthase.

Natural product reports 20031001

Redox regulation of the human xenobiotic metabolizing enzyme arylamine N-acetyltransferase 1 (NAT1). Reversible inactivation by hydrogen peroxide.

The Journal of biological chemistry 20030912

Loading peptidyl-coenzyme A onto peptidyl carrier proteins: a novel approach in characterizing macrocyclization by thioesterase domains.

Journal of the American Chemical Society 20030910

Cloning, expression, and characterization of a human 4'-phosphopantetheinyl transferase with broad substrate specificity.

The Journal of biological chemistry 20030829

Futile cycling of intermediates of fatty acid biosynthesis toward peroxisomal beta-oxidation in Saccharomyces cerevisiae.

The Journal of biological chemistry 20030829

Identification, purification, and characterization of an eukaryotic-like phosphopantetheine adenylyltransferase (coenzyme A biosynthetic pathway) in the hyperthermophilic archaeon Pyrococcus abyssi.

The Journal of biological chemistry 20030815

Reverse reaction of lysophosphatidylinositol acyltransferase. Functional reconstitution of coenzyme A-dependent transacylation system.

The Journal of biological chemistry 20030808

Glutathione depletion exacerbates methylenedianiline toxicity to biliary epithelial cells and hepatocytes in rats.

Toxicological sciences : an official journal of the Society of Toxicology 20030801

Exercise and recovery metabolism in the Pacific spiny dogfish (Squalus acanthias).

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20030801

The final player in the coenzyme A biosynthetic pathway.

Structure (London, England : 1993) 20030801

Luminescent and substrate binding activities of firefly luciferase N-terminal domain.

Biochimica et biophysica acta 20030730

Glucose alleviates ammonia-induced inhibition of short-chain fatty acid metabolism in rat colonic epithelial cells.

American journal of physiology. Gastrointestinal and liver physiology 20030701

A novel Arabidopsis acetyltransferase interacts with the geminivirus movement protein NSP.

The Plant cell 20030701

Formyl-CoA transferase encloses the CoA binding site at the interface of an interlocked dimer.

The EMBO journal 20030701

Valproyl-CoA and esterified valproic acid are not found in brains of rats treated with valproic acid, but the brain concentrations of CoA and acetyl-CoA are altered.

Neurochemical research 20030601

Basis of a high-throughput method for nuclear receptor ligands.

Journal of biochemistry 20030601

Automated generation of MCSS-derived pharmacophoric DOCK site points for searching multiconformation databases.

Proteins 20030501

Standard transformed Gibbs energies of coenzyme A derivatives as functions of pH and ionic strength.

Biophysical chemistry 20030501

An approach to identifying novel substrates of bacterial arylamine N-acetyltransferases.

Bioorganic & medicinal chemistry 20030403

Does exercise training interfere with the effects of L-carnitine supplementation?

Nutrition (Burbank, Los Angeles County, Calif.) 20030401

Functional characterization of beta-ketoacyl-ACP reductase (FabG) from Plasmodium falciparum.

Biochemical and biophysical research communications 20030328

Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase.

Science (New York, N.Y.) 20030328

The 1.75 A crystal structure of acetyl-CoA synthetase bound to adenosine-5'-propylphosphate and coenzyme A.

Biochemistry 20030318

Random-order ternary complex reaction mechanism of serine acetyltransferase from Escherichia coli.

Biochemistry 20030318

NMR investigation of the catalytic mechanism of arylamine N-acetyltransferase from Salmonella typhimurium.

Biochimica et biophysica acta 20030317

Caloric restriction increases gluconeogenic and transaminase enzyme activities in mouse liver.

Experimental gerontology 20030301

Proposed mechanism and functional amino acid residues of malonyl-CoA:anthocyanin 5-O-glucoside-6'''-O-malonyltransferase from flowers of Salvia splendens, a member of the versatile plant acyltransferase family.

Biochemistry 20030218

Effects of dynamic exercise intensity on the activation of hormone-sensitive lipase in human skeletal muscle.

The Journal of physiology 20030215

Stereochemical studies on phosphopantothenoylcysteine decarboxylase from Escherichia coli.

Bioorganic & medicinal chemistry letters 20030210

Stilbenecarboxylate biosynthesis: a new function in the family of chalcone synthase-related proteins.

Phytochemistry 20030201

Purification, cloning, and properties of an acyltransferase controlling shikimate and quinate ester intermediates in phenylpropanoid metabolism.

The Journal of biological chemistry 20030103

Separation and quantitation of short-chain coenzyme A's in biological samples by capillary electrophoresis.

Analytical chemistry 20030101

The tyranny of adenosine recognition among RNA aptamers to coenzyme A.

BMC evolutionary biology 20030101

Sir2-dependent activation of acetyl-CoA synthetase by deacetylation of active lysine.

Science (New York, N.Y.) 20021220

Pressure-assisted capillary electrophoresis electrospray ionization mass spectrometry for analysis of multivalent anions.

Analytical chemistry 20021215

The antibiotic activity of N-pentylpantothenamide results from its conversion to ethyldethia-coenzyme a, a coenzyme a antimetabolite.

The Journal of biological chemistry 20021213

Conserved residues in the putative catalytic triad of human bile acid Coenzyme A:amino acid N-acyltransferase.

The Journal of biological chemistry 20021206

Coenzyme A and short-chain acyl-CoA species in control and ischemic rat brain.

Neurochemical research 20021201

MgATP may depress de novo neuronal nuclear PAF generation by promoting the formation of alkylacylglycerophosphate, an inhibitor of alkylglycerophosphate acetyltransferase.

Biochimica et biophysica acta 20021108

Separation and identification of organic acid-coenzyme A thioesters using liquid chromatography/electrospray ionization-mass spectrometry.

Analytical and bioanalytical chemistry 20021101

X-ray structure of pyruvate formate-lyase in complex with pyruvate and CoA. How the enzyme uses the Cys-418 thiyl radical for pyruvate cleavage.

The Journal of biological chemistry 20021018

Inhibition of bovine phenol sulfotransferase (bSULT1A1) by CoA thioesters. Evidence for positive cooperativity and inhibition by interaction with both the nucleotide and phenol binding sites.

The Journal of biological chemistry 20021018

The acetyl group deficit at the onset of contraction in ischaemic canine skeletal muscle.

The Journal of physiology 20021015

Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species.

European journal of biochemistry 20021001

Molecular characterization of the 4'-phosphopantothenoylcysteine synthetase domain of bacterial dfp flavoproteins.

The Journal of biological chemistry 20020927

Kinetic, Raman, NMR, and site-directed mutagenesis studies of the Pseudomonas sp. strain CBS3 4-hydroxybenzoyl-CoA thioesterase active site.

Biochemistry 20020917

A novel biosynthetic pathway providing precursors for fatty acid biosynthesis and secondary metabolite formation in myxobacteria.

The Journal of biological chemistry 20020906

Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis in complex with coenzyme A and aminoglycoside substrates.

Nature structural biology 20020901

Effects of fasting on tissue contents of coenzyme A and related intermediates in rats.

Pediatric research 20020901

Initial characterization of a type I fatty acid synthase and polyketide synthase multienzyme complex NorS in the biosynthesis of aflatoxin B(1).

Chemistry & biology 20020901

The roles of coenzyme A in the pyruvate:ferredoxin oxidoreductase reaction mechanism: rate enhancement of electron transfer from a radical intermediate to an iron-sulfur cluster.

Biochemistry 20020806

The structure of VibH represents nonribosomal peptide synthetase condensation, cyclization and epimerization domains.

Nature structural biology 20020701

Characterization of Type I and Type II myristoyl-CoA:protein N-myristoyltransferases with the Acyl-CoAs found on heterogeneously acylated retinal proteins.

Experimental eye research 20020701

Molecular cloning of CoA Synthase. The missing link in CoA biosynthesis.

The Journal of biological chemistry 20020621

Chemical reactivity of the naproxen acyl glucuronide and the naproxen coenzyme A thioester towards bionucleophiles.

Journal of pharmaceutical and biomedical analysis 20020620

Complete reconstitution of the human coenzyme A biosynthetic pathway via comparative genomics.

The Journal of biological chemistry 20020614

A bicyclic autotrophic CO2 fixation pathway in Chloroflexus aurantiacus.

The Journal of biological chemistry 20020607

The murine pantothenate kinase (Pank1) gene encodes two differentially regulated pantothenate kinase isozymes.

Gene 20020529

Purification and characterization of benzoate:coenzyme A ligase from Clarkia breweri.

Archives of biochemistry and biophysics 20020415

CoASH and CoASSG levels in lungs of hyperoxic rats as potential biomarkers of intramitochondrial oxidant stresses.

Pediatric research 20020301

Purification and characterisation of the BIOH protein from the biotin biosynthetic pathway.

FEBS letters 20020227

Ring scission of diastereomeric 4-butylspiropentylcarbinyl radicals as a chemical model for identifying enzyme-catalyzed FAD adducts resulting from spiropentylacetyl-CoA.

Journal of the American Chemical Society 20020220

Cloning and characterization of a novel human pantothenate kinase gene.

The international journal of biochemistry & cell biology 20020201

Alternate substrates of human glutaryl-CoA dehydrogenase: structure and reactivity of substrates, and identification of a novel 2-enoyl-CoA product.

Biochemistry 20020129

Characterization of an acyl-coA thioesterase that functions as a major regulator of peroxisomal lipid metabolism.

The Journal of biological chemistry 20020111

The Caenorhabditis elegans Y87G2A.14 Nudix hydrolase is a peroxisomal coenzyme A diphosphatase.

BMC biochemistry 20020101

Pantothenic acid: an organ-specific pro-oxidant vitamin. Brain and liver neuroprostane levels in rats fed a pantothenic acid-deficient diet.

Advances in experimental medicine and biology 20020101

Role of active site binding interactions in 4-chlorobenzoyl-coenzyme A dehalogenase catalysis.

Biochemistry 20011225

Enzymology. Coenzymes and radicals.

Science (New York, N.Y.) 20011221

Structure-guided programming of polyketide chain-length determination in chalcone synthase.

Biochemistry 20011211

In vitro reconstitution and analysis of the chain initiating enzymes of the R1128 polyketide synthase.

Biochemistry 20011211

Synergism between ERalpha transactivation function 1 (AF-1) and AF-2 mediated by steroid receptor coactivator protein-1: requirement for the AF-1 alpha-helical core and for a direct interaction between the N- and C-terminal domains.

Molecular endocrinology (Baltimore, Md.) 20011101

Role of a highly conserved YPITP motif in 2-oxoacid:ferredoxin oxidoreductase: heterologous expression of the gene from Sulfolobus sp.strain 7, and characterization of the recombinant and variant enzymes.

European journal of biochemistry 20011101

Coenzyme A stimulates collagen production in cultured fibroblasts; possible mechanisms in enzymatic and gene expression.

Archives of dermatological research 20011101

Crystal structure of dephospho-coenzyme A kinase from Haemophilus influenzae.

Journal of structural biology 20011101

Brain amino acid metabolism and ketosis.

Journal of neuroscience research 20011015

beta-Oxidation of simvastatin in mouse liver preparations.

Drug metabolism and disposition: the biological fate of chemicals 20011001

A mechanism of benzoic acid biosynthesis in plants and bacteria that mirrors fatty acid beta-oxidation.

Chembiochem : a European journal of chemical biology 20011001

Studies on phytanoyl-CoA 2-hydroxylase and synthesis of phytanoyl-coenzyme A.

Bioorganic & medicinal chemistry letters 20010917

Mitochondrial thiol status in the liver is altered by exposure to hyperoxia.

Toxicology letters 20010915

Regulation of catalytic activity of a multifunctional polyketide biosynthetic enzyme, 6-hydroxymellein synthase, by interaction between NADPH and phenylglyoxal-sensitive amino acid residue at the reaction center.

Biochimica et biophysica acta 20010910

Formation of retinoyl-CoA in rat tissues.

Journal of biochemistry 20010901

Simultaneous detection of cholyl adenylate and coenzyme A thioester utilizing liquid chromatography/electrospray ionization mass spectrometry.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010901

Adenine recognition: a motif present in ATP-, CoA-, NAD-, NADP-, and FAD-dependent proteins.

Proteins 20010815

Yeast cytoplasmic and mitochondrial methionyl-tRNA synthetases: two structural frameworks for identical functions.

Journal of molecular biology 20010803

Bisubstrate ketone analogues as serotonin N-acetyltransferase inhibitors.

Journal of medicinal chemistry 20010719

Mechanistic studies on phosphopantothenoylcysteine decarboxylase.

Journal of the American Chemical Society 20010704

The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives.

The Biochemical journal 20010701

Characterization of the reaction mechanism for the XL-I form of bovine liver xenobiotic/medium-chain fatty acid:CoA ligase.

The Biochemical journal 20010701

Acyl-CoA esters antagonize the effects of ligands on peroxisome proliferator-activated receptor alpha conformation, DNA binding, and interaction with Co-factors.

The Journal of biological chemistry 20010615

Synthesis of coenzyme A esters of 3alpha,7alpha,12alpha-trihydroxy- and 3alpha,7alpha-dihydroxy-24-oxo-5beta-cholestan-26-oic acids for the study of beta-oxidation in bile acid biosynthesis.

Steroids 20010601

Arabidopsis thaliana flavoprotein AtHAL3a catalyzes the decarboxylation of 4'-Phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis.

The Journal of biological chemistry 20010601

Biochemical characterization of the reverse activity of rat brain ceramidase. A CoA-independent and fumonisin B1-insensitive ceramide synthase.

The Journal of biological chemistry 20010518

Metabolic, idiosyncratic toxicity of drugs: overview of the hepatic toxicity induced by the anxiolytic, panadiplon.

Chemico-biological interactions 20010516

Standard apparent reduction potentials for biochemical half reactions as a function of pH and ionic strength.

Archives of biochemistry and biophysics 20010501

Structure and function of histone acetyltransferases.

Cellular and molecular life sciences : CMLS 20010501

Phosphopantothenoylcysteine synthetase from Escherichia coli. Identification and characterization of the last unidentified coenzyme A biosynthetic enzyme in bacteria.

The Journal of biological chemistry 20010427

Nitric oxide-dependent nitrosation of cellular CoA: a proposal for tissue responses.

Nitric oxide : biology and chemistry 20010401

fumble encodes a pantothenate kinase homolog required for proper mitosis and meiosis in Drosophila melanogaster.

Genetics 20010301

Retinoylation of proteins in cell-free fractions of rat tissues in vitro.

Biochimica et biophysica acta 20010226

Structure of the Escherichia coli GlmU pyrophosphorylase and acetyltransferase active sites.

Biochemistry 20010220

Characterization of the reversible nature of the reaction catalyzed by sphingolipid ceramide N-deacylase. A novel form of reverse hydrolysis reaction.

European journal of biochemistry 20010201

CoenzymeA glutathione disulfide is a potent modulator of angiotensin II-induced vasoconstriction.

American journal of hypertension 20010201

The biosynthesis of coenzyme A in bacteria.

Vitamins and hormones 20010101

Properties of firefly luciferase immobilized through a biotin carboxyl carrier protein domain.

Luminescence : the journal of biological and chemical luminescence 20010101

Adenine and guanine nucleotide-specific succinyl-CoA synthetases in the clonal beta-cell mitochondria: implications in the beta-cell high-energy phosphate metabolism in relation to physiological insulin secretion.

Diabetologia 20010101

Significance of pantothenate for glucose fermentation by Oenococcus oeni and for suppression of the erythritol and acetate production.

Archives of microbiology 20010101

Glutathione is a target in tellurite toxicity and is protected by tellurite resistance determinants in Escherichia coli.

Canadian journal of microbiology 20010101

Identification of triphosphoribosyl-dephospho-CoA as precursor of the citrate lyase prosthetic group.

FEBS letters 20001020

NADPH-dependent reductive ortho dehalogenation of 2,4-dichlorobenzoic acid in Corynebacterium sepedonicum KZ-4 and Coryneform bacterium strainNTB-1 via 2,4-dichlorobenzoyl coenzyme A.

Journal of bacteriology 19960501

Free and esterified coenzyme A in the liver and muscles of chronically hyperammonemic mice treated with sodium benzoate.

Biochemical and molecular medicine 19950401

Cardiac glucose and fatty acid oxidation in the streptozotocin-induced diabetic spontaneously hypertensive rat.

Hypertension (Dallas, Tex. : 1979) 19950201

ERG10 from Saccharomyces cerevisiae encodes acetoacetyl-CoA thiolase.

The Journal of biological chemistry 19941216

Anaerobic degradation of pimelate by newly isolated denitrifying bacteria.

Microbiology (Reading, England) 19940201

Products of enzymatic reduction of benzoyl-CoA, a key reaction in anaerobic aromatic metabolism.

European journal of biochemistry 19930201

Stereospecificity of the inhibition by etomoxir of fatty acid and cholesterol synthesis in isolated rat hepatocytes.

Biochemical pharmacology 19911009

Novel enzymic hydrolytic dehalogenation of a chlorinated aromatic.

Science (New York, N.Y.) 19910712

Identification of the principal catalytically important acidic residue of 3-hydroxy-3-methylglutaryl coenzyme A reductase.

The Journal of biological chemistry 19901215

2-Aminobenzoyl-CoA monooxygenase/reductase, a novel type of flavoenzyme. Identification of the reaction products.

European journal of biochemistry 19900731

Microbial metabolism of short-chain unsaturated hydrocarbons.

FEMS microbiology reviews 19890901

Oxfenicine-induced accumulation of lipid in the rat myocardium.

Journal of molecular and cellular cardiology 19880301

Glutaconate CoA-transferase from Acidaminococcus fermentans.

European journal of biochemistry 19810801

Enzymes of 2-oxo acid degradation and biosynthesis in cell-free extracts of mixed rumen micro-organisms.

The Biochemical journal 19760801

Incorporation of (1-14C)palmitoyl-CoA into phosphatidylcholine by plasma membranes of rat submaxillary glands in vitro.

European journal of biochemistry 19760102

On the mechanism of ketogenesis and its control. Purification, kinetic mechanism and regulation of different forms of mitochondrial acetoacetyl-CoA thiolases from ox liver.

European journal of biochemistry 19751115

An alkyl etherase in rat liver.

The Journal of physiology 19751101

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Steroids 19751001

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Solubilization and purification of beta-hydroxy-beta-methylglutaryl coenzyme A reductase from rat liver.

Biochemistry 19700414

NADH-dependent synthesis of butyric acid by rabbit mammary gland mitochondrial enzymes.

Archives of biochemistry and biophysics 19690901

The absolute configuration of methylmalonyl coenzyme A and stereochemistry of the methymalonyl coenzyme A mutase reaction.

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DITHIOTHREITOL, A NEW PROTECTIVE REAGENT FOR SH GROUPS.

Biochemistry 19640401

The structure of coenzyme A.

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Studies concerning the structure of coenzyme A.

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