N-Cyclohexyl-N-methyl-4-((2-oxo-1,2-dihydroquinolin-6-yl)oxy)butanamide
| Title | Journal |
|---|---|
| Effects of lipoic acid on lipolysis in 3T3-L1 adipocytes. | Journal of lipid research 20121101 |
| Pharmacologic agents elevating cAMP prevent arginase II expression and proliferation of pulmonary artery smooth muscle cells. | American journal of respiratory cell and molecular biology 20120801 |
| Gap junction-mediated communications regulate chromatin remodeling during bovine oocyte growth and differentiation through cAMP-dependent mechanism(s). | Biology of reproduction 20111201 |
| Acylated and unacylated ghrelin attenuate isoproterenol-induced lipolysis in isolated rat visceral adipocytes through activation of phosphoinositide 3-kinase γ and phosphodiesterase 3B. | Biochimica et biophysica acta 20110601 |
| Neurite outgrowth mediated by translation elongation factor eEF1A1: a target for antiplatelet agent cilostazol. | PloS one 20110101 |
| Simulated physiological oocyte maturation (SPOM): a novel in vitro maturation system that substantially improves embryo yield and pregnancy outcomes. | Human reproduction (Oxford, England) 20101201 |
| Anagrelide represses GATA-1 and FOG-1 expression without interfering with thrombopoietin receptor signal transduction. | Journal of thrombosis and haemostasis : JTH 20101001 |
| Function of cardiac beta1- and beta2-adrenoceptors of newborn piglets: role of phosphodiesterases PDE3 and PDE4. | European journal of pharmacology 20100725 |
| A role of phosphodiesterase-3B pathway in mediating leptin action on proopiomelanocortin and neurotensin neurons in the hypothalamus. | Neuroscience letters 20100719 |
| PDE5A suppression of acute beta-adrenergic activation requires modulation of myocyte beta-3 signaling coupled to PKG-mediated troponin I phosphorylation. | Basic research in cardiology 20100501 |
| Decreased expression and activity of cAMP phosphodiesterases in cardiac hypertrophy and its impact on beta-adrenergic cAMP signals. | Circulation research 20091009 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Design, synthesis and pharmacological evaluation of 6-hydroxy-4-methylquinolin-2(1H)-one derivatives as inotropic agents. | Journal of enzyme inhibition and medicinal chemistry 20090801 |
| Effects of the cAMP-elevating agents cilostamide, cilostazol and forskolin on the phosphorylation of Akt and GSK-3beta in platelets. | Thrombosis and haemostasis 20090801 |
| Cilostamide produces hyperpolarization associated with K(ATP) channel activation, but does not augment endothelium-derived hyperpolarization in rat mesenteric arteries. | Clinical and experimental pharmacology & physiology 20090701 |
| Phosphodiesterases PDE3 and PDE4 jointly control the inotropic effects but not chronotropic effects of (-)-CGP12177 despite PDE4-evoked sinoatrial bradycardia in rat atrium. | Naunyn-Schmiedeberg's archives of pharmacology 20090401 |
| Inotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart. | British journal of pharmacology 20090101 |
| Ontogenic changes of the control by phosphodiesterase-3 and -4 of 5-HT responses in porcine heart and relevance to human atrial 5-HT(4) receptors. | British journal of pharmacology 20090101 |
| Phosphodiesterase 3 is present in rabbit and human erythrocytes and its inhibition potentiates iloprost-induced increases in cAMP. | American journal of physiology. Heart and circulatory physiology 20080801 |
| Effect of temporary nuclear arrest by phosphodiesterase 3-inhibitor on morphological and functional aspects of in vitro matured mouse oocytes. | Molecular reproduction and development 20080601 |
| Spatiotemporal dynamics of beta-adrenergic cAMP signals and L-type Ca2+ channel regulation in adult rat ventricular myocytes: role of phosphodiesterases. | Circulation research 20080509 |
| Effects of cilostamide and forskolin on the meiotic resumption and embryonic development of immature human oocytes. | Human reproduction (Oxford, England) 20080301 |
| Phosphodiesterase-4 blunts inotropism and arrhythmias but not sinoatrial tachycardia of (-)-adrenaline mediated through mouse cardiac beta(1)-adrenoceptors. | British journal of pharmacology 20080201 |
| Numerous distinct PKA-, or EPAC-based, signalling complexes allow selective phosphodiesterase 3 and phosphodiesterase 4 coordination of cell adhesion. | Cellular signalling 20071201 |
| The effects of both noradrenaline and CGP12177, mediated through human beta1 -adrenoceptors, are reduced by PDE3 in human atrium but PDE4 in CHO cells. | Naunyn-Schmiedeberg's archives of pharmacology 20070401 |
| Cilostamide potentiates more the positive inotropic effects of (-)-adrenaline through beta(2)-adrenoceptors than the effects of (-)-noradrenaline through beta (1)-adrenoceptors in human atrial myocardium. | Naunyn-Schmiedeberg's archives of pharmacology 20061201 |
| Phosphodiesterase PDE3 blunts the positive inotropic and cyclic AMP enhancing effects of CGP12177 but not of noradrenaline in rat ventricle. | British journal of pharmacology 20060101 |
| New insight into the role of phosphodiesterase 3A in porcine oocyte maturation. | BMC developmental biology 20060101 |
| Effects of long-term in vitro exposure to phosphodiesterase type-3 inhibitors on follicle and oocyte development. | Reproduction (Cambridge, England) 20050801 |
| The phosphodiesterase 3 inhibitor cilostamide enhances inotropic responses to glucagon but not to dobutamine in rat ventricular myocardium. | European journal of pharmacology 20050411 |
| Fundamental significance of specific phosphodiesterases in the control of spontaneous meiotic resumption in porcine oocytes. | Molecular reproduction and development 20050301 |
| Vascular endothelial cell cyclic nucleotide phosphodiesterases and regulated cell migration: implications in angiogenesis. | Molecular pharmacology 20050101 |
| Mouse oocyte meiotic resumption and polar body extrusion in vitro are differentially influenced by FSH, epidermal growth factor and meiosis-activating sterol. | Human reproduction (Oxford, England) 20041201 |
| The action mechanism of zinc(II) complexes with insulinomimetic activity in rat adipocytes. | Life sciences 20040625 |
| Identification of purine inhibitors of phosphodiesterase 7 (PDE7). | Bioorganic & medicinal chemistry letters 20040607 |
| Impaired activation of phosphatidylinositol 3-kinase by leptin is a novel mechanism of hepatic leptin resistance in diet-induced obesity. | The Journal of biological chemistry 20040521 |
| Augmentation of lipolysis in adipocytes from fed rats, but not from starved rats, by inhibition of rolipram-sensitive phosphodiesterase 4. | Archives of biochemistry and biophysics 20040501 |
| Benzyl vinylogous amide substituted aryldihydropyridazinones and aryldimethylpyrazolones as potent and selective PDE3B inhibitors. | Bioorganic & medicinal chemistry letters 20031117 |
| Synthesis and pharmacological characterization of functionalized 2-pyridones structurally related to the cardiotonic agent milrinone. | Bioorganic & medicinal chemistry 20031103 |
| The role of tryptophan 1072 in human PDE3B inhibitor binding. | Biochemical and biophysical research communications 20030808 |
| Phosphodiesterase 3 activity is reduced in dog lung following pacing-induced heart failure. | American journal of physiology. Lung cellular and molecular physiology 20030501 |
| Phosphodiesterase 3 inhibitors selectively block the spontaneous resumption of meiosis by macaque oocytes in vitro. | Human reproduction (Oxford, England) 20020801 |
| Changes in phosphodiesterase activity in the developing rat submandibular gland. | Archives of oral biology 20020801 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Differential effects of specific phosphodiesterase isoenzyme inhibitors on bovine oocyte meiotic maturation. | Developmental biology 20020415 |
| Altered phosphodiesterase 3-mediated cAMP hydrolysis contributes to a hypermotile phenotype in obese JCR:LA-cp rat aortic vascular smooth muscle cells: implications for diabetes-associated cardiovascular disease. | Diabetes 20020401 |
| Inhibition of PDE3B augments PDE4 inhibitor-induced apoptosis in a subset of patients with chronic lymphocytic leukemia. | Clinical cancer research : an official journal of the American Association for Cancer Research 20020201 |
| Mechanism of intracellular calcium ([Ca2+]i) inhibition of lipolysis in human adipocytes. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011101 |
| Inhibitors of phosphodiesterase isoforms III or IV suppress islet-cell nitric oxide production. | Laboratory investigation; a journal of technical methods and pathology 20010801 |
| Cyclic GMP regulation of the L-type Ca(2+) channel current in human atrial myocytes. | The Journal of physiology 20010601 |
| Characterization of an in vivo hormonally regulated phosphodiesterase 3 (PDE3) associated with a liver Golgi-endosomal fraction. | Archives of biochemistry and biophysics 20010301 |
| Potent effects of novel anti-platelet aggregatory cilostamide analogues on recombinant cyclic nucleotide phosphodiesterase isozyme activity. | Biochemical pharmacology 20000215 |
| Inhibitors of cyclic AMP phosphodiesterase. 1. Analogues of cilostamide and anagrelide. | Journal of medicinal chemistry 19870201 |