Home Other Building Blocks Butyl Benzyl Phthalate

Butyl Benzyl Phthalate

CAS No.:
85-68-7
Catalog Number:
AG0034KL
Molecular Formula:
C19H20O4
Molecular Weight:
312.3597
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
95%
In Stock USA
United States
$33
- +
5g
95%
In Stock USA
United States
$47
- +
25g
95%
In Stock USA
United States
$87
- +
100g
95%
In Stock USA
United States
$172
- +
Product Description
Catalog Number:
AG0034KL
Chemical Name:
Butyl Benzyl Phthalate
CAS Number:
85-68-7
Molecular Formula:
C19H20O4
Molecular Weight:
312.3597
MDL Number:
MFCD00009440
IUPAC Name:
2-O-benzyl 1-O-butyl benzene-1,2-dicarboxylate
InChI:
InChI=1S/C19H20O4/c1-2-3-13-22-18(20)16-11-7-8-12-17(16)19(21)23-14-15-9-5-4-6-10-15/h4-12H,2-3,13-14H2,1H3
InChI Key:
IRIAEXORFWYRCZ-UHFFFAOYSA-N
SMILES:
CCCCOC(=O)c1ccccc1C(=O)OCc1ccccc1
EC Number:
201-622-7
UNII:
YPC4PJX59M
NSC Number:
71001
RTECS Number:
TH9990000
UN Number:
3082
Properties
Complexity:
374  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
312.136g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
312.365g/mol
Monoisotopic Mass:
312.136g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
52.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
4.9  
Literature
Title Journal
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Curcumin inhibits adipogenesis induced by benzyl butyl phthalate in 3T3-L1 cells. Toxicology and applied pharmacology 20170815
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Molecularly imprinted microspheres and nanospheres for di(2-ethylhexyl)phthalate prepared by precipitation polymerization. Analytical and bioanalytical chemistry 20070901
Hershberger assay for antiandrogenic effects of phthalates. Journal of toxicology and environmental health. Part A 20070801
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Benzyl butyl phthalate influences actin distribution and cell proliferation in rat Py1a osteoblasts. Journal of cellular biochemistry 20070601
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Simultaneous determination of seven phthalates and four parabens in cosmetic products using HPLC-DAD and GC-MS methods. Journal of separation science 20070101
The plasticizer butyl benzyl phthalate induces genomic changes in rat mammary gland after neonatal/prepubertal exposure. BMC genomics 20070101
[Effects of subchronic exposure of laboratory mice to benzylbutyl phthalate (BBP) on the quantity and quality of male germ cells]. Roczniki Panstwowego Zakladu Higieny 20070101
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. Journal of molecular graphics & modelling 20061101
Experimental parameters affecting sensitivity and specificity of a yeast assay for estrogenic compounds: results of an interlaboratory validation exercise. Analytical and bioanalytical chemistry 20061101
Altered semen quality in relation to urinary concentrations of phthalate monoester and oxidative metabolites. Epidemiology (Cambridge, Mass.) 20061101
Effects of possible endocrine disrupting chemicals on bacterial component-induced activation of NF-kappaB. Biological & pharmaceutical bulletin 20061001
Agricultural pesticide use and hypospadias in eastern Arkansas. Environmental health perspectives 20061001
Elucidation of n-butyl benzyl phthalate biodegradation using high-performance liquid chromatography and gas chromatography-mass spectrometry. Analytical and bioanalytical chemistry 20060901
Exposure to phthalates in neonatal intensive care unit infants: urinary concentrations of monoesters and oxidative metabolites. Environmental health perspectives 20060901
Estrogenic activity of phthalate esters by in vitro VTG assay using primary-cultured Xenopus hepatocytes. Dental materials journal 20060901
Considerations on ultra-trace analysis of phthalates in drinking water. Water research 20060701
A biomimetic approach to the detection and identification of estrogen receptor agonists in surface waters using semipermeable membrane devices (SPMDs) and bioassay-directed chemical analysis. Environmental science and pollution research international 20060701
Diisobutyl phthalate has comparable anti-androgenic effects to di-n-butyl phthalate in fetal rat testis. Toxicology letters 20060601
Estimated daily phthalate exposures in a population of mothers of male infants exhibiting reduced anogenital distance. Environmental health perspectives 20060601
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Association of phthalate esters with endometriosis in Indian women. BJOG : an international journal of obstetrics and gynaecology 20060501
Disruption of reproductive development in male rat offspring following in utero exposure to phthalate esters. International journal of andrology 20060201
Making progress on breast cancer. Environmental health perspectives 20060201
Butyl benzyl phthalate blocks Ca2+ signaling coupled with purinoceptor in rat PC12 cells. Toxicology and applied pharmacology 20060101
Validity of anogenital distance as a marker of in utero phthalate exposure. Environmental health perspectives 20060101
Determination of phthalates in milk and milk products by liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20060101
Analysis of consumer cosmetic products for phthalate esters. Journal of cosmetic science 20060101
DNA methylation of estrogen receptor alpha gene by phthalates. Journal of toxicology and environmental health. Part A 20051210
Detection of thyroid system-disrupting chemicals using in vitro and in vivo screening assays in Xenopus laevis. Toxicological sciences : an official journal of the Society of Toxicology 20051201
Effects of endocrine disruptors on the formation of prostaglandin and arachidonoyl-CoA formed from arachidonic acid in rabbit kidney medulla microsomes. Prostaglandins, leukotrienes, and essential fatty acids 20051201
The promoter of the human sodium/iodide symporter responds to certain phthalate plasticisers. Molecular and cellular endocrinology 20051201
Modulation of iodide uptake by dialkyl phthalate plasticisers in FRTL-5 rat thyroid follicular cells. Molecular and cellular endocrinology 20051201
Two-generation reproductive toxicity studies in rats with extra parameters for detecting endocrine disrupting activity: introductory overview of results for nine chemicals. The Journal of toxicological sciences 20051201
A two-generation reproductive toxicity study of butyl benzyl phthalate in rats. The Journal of toxicological sciences 20051201
Are EDCs blurring issues of gender? Environmental health perspectives 20051001
Phthalates in indoor dust and their association with building characteristics. Environmental health perspectives 20051001
Phthalate exposure during pregnancy and lower anogenital index in boys: wider implications for the general population? Environmental health perspectives 20050801
Decrease in anogenital distance among male infants with prenatal phthalate exposure. Environmental health perspectives 20050801
Determination of phthalate esters in cosmetics by gas chromatography with flame ionization detection and mass spectrometric detection. International journal of cosmetic science 20050801
Gene expression profiling following in utero exposure to phthalate esters reveals new gene targets in the etiology of testicular dysgenesis. Biology of reproduction 20050701
[Biodegradation of butylbenzyl phthalate by acclimated activated sludge]. Huan jing ke xue= Huanjing kexue 20050701
Differential effects of phthalate esters on transcriptional activities via human estrogen receptors alpha and beta, and androgen receptor. Toxicology 20050601
Simultaneous screening and determination eight phthalates in plastic products for food use by sonication-assisted extraction/GC-MS methods. Talanta 20050430
Multivariate optimization of a solid-phase microextraction method for the analysis of phthalate esters in environmental waters. Journal of chromatography. A 20050422
Exposure of nursery school children and their parents and teachers to di-n-butylphthalate and butylbenzylphthalate. International archives of occupational and environmental health 20050401
Alkyl phenols and diethylhexyl phthalate in tissues of sheep grazing pastures fertilized with sewage sludge or inorganic fertilizer. Environmental health perspectives 20050401
Evidence of interaction between polychlorinated biphenyls and phthalates in relation to human sperm motility. Environmental health perspectives 20050401
Conflict of estrogenic activity by various phthalates between in vitro and in vivo models related to the expression of Calbindin-D9k. The Journal of reproduction and development 20050401
Potential selection biases. Environmental health perspectives 20050301
Human colon microbiota transform polycyclic aromatic hydrocarbons to estrogenic metabolites. Environmental health perspectives 20050101
Pathways in the degradation of hydrolyzed alcohols of butyl benzyl phthalate in metabolically diverse Gordonia sp. strain MTCC 4818. Journal of molecular microbiology and biotechnology 20050101
Induction and inhibition of oocyte maturation by EDCs in zebrafish. Reproductive biology and endocrinology : RB&E 20050101
A mixture of the 'antiandrogens' linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion. Biology of reproduction 20041201
Phthalates inhibit tamoxifen-induced apoptosis in MCF-7 human breast cancer cells. Journal of toxicology and environmental health. Part A 20041201
Temporal variability of urinary phthalate metabolite levels in men of reproductive age. Environmental health perspectives 20041201
The association between asthma and allergic symptoms in children and phthalates in house dust: a nested case-control study. Environmental health perspectives 20041001
Phthalate treatment does not influence levels of IgE or Th2 cytokines in B6C3F1 mice. Toxicology 20040901
Identification and quantification of n-octyl esters of alkanoic and hexanedioic acids and phthalates as urban wastewater markers in biota and sediments from estuarine areas. Journal of chromatography. A 20040813
Suppression by phthalates of the calcium signaling of human nicotinic acetylcholine receptors in human neuroblastoma SH-SY5Y cells. Toxicology 20040805
Phthalate exposure and early thelarche. Environmental health perspectives 20040701
Effect of endocrine disrupting chemicals on lipopolysaccharide-induced tumor necrosis factor-alpha and nitric oxide production by mouse macrophages. Biological & pharmaceutical bulletin 20040701
[Analysis of the phthalates in cosmetics by capillary gas chromatography]. Se pu = Chinese journal of chromatography 20040501
Lack of modifying effects of 4-ter t-octylphenol and benzyl butyl phthalate on 3,2-dimethyl-4-aminobiphenyl-induced prostate carcinogenesis in rats. Cancer science 20040401
Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis. Toxicology letters 20040202
Postexposure effects of DDE and butylbenzylphthalate on feeding behavior in threespine stickleback. Ecotoxicology and environmental safety 20040201
Reproductive toxicity evaluation of dietary butyl benzyl phthalate (BBP) in rats. Reproductive toxicology (Elmsford, N.Y.) 20040101
[Reproductive toxicity and functional mechanism of the environmental hormone butylbenzyl phthalate]. Huan jing ke xue= Huanjing kexue 20040101
Anogenital distance in human male and female newborns: a descriptive, cross-sectional study. Environmental health : a global access science source 20040101
Prenatal exposures to phthalates among women in New York City and Krakow, Poland. Environmental health perspectives 20031101
[PAEs in composts of municipal sludge and rice straw]. Ying yong sheng tai xue bao = The journal of applied ecology 20031101
The effect of endocrine disrupting chemicals on thyroid hormone binding to Japanese quail transthyretin and thyroid hormone receptor. General and comparative endocrinology 20031015
Study of 202 natural, synthetic, and environmental chemicals for binding to the androgen receptor. Chemical research in toxicology 20031001
Metabolism of butyl benzyl phthalate by Gordonia sp. strain MTCC 4818. Biochemical and biophysical research communications 20030912
Activation of PPARalpha and PPARgamma by environmental phthalate monoesters. Toxicological sciences : an official journal of the Society of Toxicology 20030801
Estimation of estrogenic and anti-estrogenic activities of some phthalate diesters and monoesters by MCF-7 cell proliferation assay in vitro. Biological & pharmaceutical bulletin 20030801
Full activation of estrogen receptor alpha activation function-1 induces proliferation of breast cancer cells. The Journal of biological chemistry 20030718
Estrogenic activity of tissue conditioners in vitro. Dental materials : official publication of the Academy of Dental Materials 20030601
Estimated daily intake of plasticizers in 1-week duplicate diet samples following regulation of DEHP-containing PVC gloves in Japan. Food additives and contaminants 20030401
Investigation of the adjuvant and immuno-suppressive effects of benzyl butyl phthalate, phthalic acid and benzyl alcohol in a murine injection model. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20030301
NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Butyl Benzyl Phthalate (BBP). NTP CERHR MON 20030301
Gas chromatography-mass spectrometry determination of the migration of phthalate plasticisers from polyvinyl chloride toys and childcare articles. Journal of chromatography. A 20030103
Butyl benzyl phthalate blocks Ca2+ signaling and catecholamine secretion coupled with nicotinic acetylcholine receptors in bovine adrenal chromaffin cells. Neurotoxicology 20030101
Decreased anogenital distance and increased incidence of undescended testes in fetuses of rats given monobenzyl phthalate, a major metabolite of butyl benzyl phthalate. Reproductive toxicology (Elmsford, N.Y.) 20030101
Comparative embryotoxicities of butyl benzyl phthalate, mono-n-butyl phthalate and mono-benzyl phthalate in mice and rats: in vivo and in vitro observations. Reproductive toxicology (Elmsford, N.Y.) 20030101
Effects of phthalate esters on actin cytoskeleton of Py1a rat osteoblasts. Histology and histopathology 20021001
Generation of anticalins with specificity for a nonsymmetric phthalic acid ester. Analytical biochemistry 20020915
Comparison of embryotoxicity of ESBO and phthalate esters using an in vitro battery system. Toxicology in vitro : an international journal published in association with BIBRA 20020801
Butyl benzyl phthalate, an endocrine disrupter, inhibits pulsatile luteinizing hormone secretion under an insulin-induced hypoglycaemic state in ovariectomized rats. Journal of neuroendocrinology 20020601
Butyl benzyl phthalate affects shoaling behavior and bottom-dwelling behavior in threespine stickleback. Environmental research 20020601
The association between biomarker-based exposure estimates for phthalates and demographic factors in a human reference population. Environmental health perspectives 20020401
Effects on development of the reproductive system in male offspring of rats given butyl benzyl phthalate during late pregnancy. Reproductive toxicology (Elmsford, N.Y.) 20020101
[Determination of monoester metabolites of butylbenzyl phthalate (BBP) by GC-MS in the urine of exposed workers]. Acta clinica Belgica 20020101
Preparation of samples for gas chromatography/mass spectrometry analysis of phthalate and adipate esters in plasma and beverages by steam distillation and extraction. Journal of AOAC International 20020101
NTP Center for the Evaluation of Risks to Human Reproduction: phthalates expert panel report on the reproductive and developmental toxicity of butyl benzyl phthalate. Reproductive toxicology (Elmsford, N.Y.) 20020101
A biomarker approach to measuring human dietary exposure to certain phthalate diesters. Food additives and contaminants 20011201
Response of MCF-7 human breast cancer cells to some binary mixtures of oestrogenic compounds in-vitro. The Journal of pharmacy and pharmacology 20011101
The endocrine disrupters butyl benzyl phthalate and bisphenol A increase the expression of progesterone receptor messenger ribonucleic acid in the preoptic area of adult ovariectomized rats. Neuroendocrinology 20010801
Phthalate esters influence FGF-2 translocation in Py1a rat osteoblasts. European journal of morphology 20010701
Environmental xenoestrogens, antiandrogens and disorders of male sexual differentiation. Molecular and cellular endocrinology 20010610
Estrogenic activity and metabolism of n-butyl benzyl phthalate in vitro: identification of the active molecule(s). Toxicology and applied pharmacology 20010415
Structure-activity relationships for a large diverse set of natural, synthetic, and environmental estrogens. Chemical research in toxicology 20010301
Effect of butyl benzyl phthalate on reproduction and zinc metabolism. Toxicology 20010221
Occurrence of organic pollutants in recovered soil fines from construction and demolition waste. Waste management (New York, N.Y.) 20010101
Effects of endocrine disrupting chemicals on the microtubule network in Chinese hamster V79 cells in culture and in Sertoli cells in rats. Teratogenesis, carcinogenesis, and mutagenesis 20010101
Female infertility--effect of perinatal xenoestrogen exposure on reproductive functions in animals and humans. Folia histochemica et cytobiologica 20010101
Differential estrogen receptor binding of estrogenic substances: a species comparison. The Journal of steroid biochemistry and molecular biology 20001115
Estrogenic activity of chemicals for dental and similar use in vitro. Journal of materials science. Materials in medicine 20000801
Several environmental oestrogens are also anti-androgens. The Journal of endocrinology 19980901
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