Biapenem
| Title | Journal |
|---|---|
| In vivo efficacy and pharmacokinetics of biapenem in a murine model of ventilator-associated pneumonia with Pseudomonas aeruginosa. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20120801 |
| Biapenem inactivation by B2 metallo β-lactamases: energy landscape of the post-hydrolysis reactions. | PloS one 20120101 |
| [Determination of biapenem in human plasma by high performance liquid chromatography]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110701 |
| Clinical efficacy and safety of biapenem for febrile neutropenia in patients with underlying hematopoietic diseases: a multi-institutional study. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110201 |
| Improved RP-HPLC method to determine biapenem in human plasma/urine and its application to a pharmacokinetic study. | Arzneimittel-Forschung 20110101 |
| In vitro activity of biapenem against Burkholderia pseudomallei. | International journal of antimicrobial agents 20100501 |
| HPLC method for measuring meropenem and biapenem concentrations in human peritoneal fluid and bile: application to comparative pharmacokinetic investigations. | Journal of chromatographic science 20100101 |
| A multicenter, randomized controlled clinical study on biapenem and imipenem/cilastatin injection in the treatment of respiratory and urinary tract infections. | Chemotherapy 20100101 |
| Common mechanistic features among metallo-beta-lactamases: a computational study of Aeromonas hydrophila CphA enzyme. | The Journal of biological chemistry 20091009 |
| Metallo-beta-lactamase inhibitory activity of phthalic acid derivatives. | Bioorganic & medicinal chemistry letters 20090901 |
| Pharmacokinetics and pharmacodynamics of biapenem in human cerebrospinal fluid. | International journal of antimicrobial agents 20090801 |
| The stability of biapenem and structural identification of impurities in aqueous solution. | Journal of pharmaceutical and biomedical analysis 20090501 |
| [Dosing regimen rationalization of biapenem in pediatric patients: use of Monte Carlo simulation]. | The Japanese journal of antibiotics 20090201 |
| Clinical and microbiological effects of biapenem in febrile neutropenic patients with hematologic malignancies. | Scandinavian journal of infectious diseases 20090101 |
| Pharmacodynamic evaluation of biapenem in peritoneal fluid using population pharmacokinetic modelling and Monte Carlo simulation. | International journal of antimicrobial agents 20081001 |
| Bacteremia caused by Desulfovibrio fairfieldensis. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20081001 |
| Pharmacokinetics and pharmacodynamics of biapenem in critically ill patients under continuous venovenous hemodiafiltration. | The Japanese journal of antibiotics 20081001 |
| [Clinical effects of biapenem on febrile neutropenia in patients with hematological malignancy]. | The Japanese journal of antibiotics 20080601 |
| Population pharmacokinetics and pharmacodynamics of biapenem in paediatric patients. | Journal of clinical pharmacy and therapeutics 20080401 |
| [Clinical investigation on target value of T>MIC in carbapenems]. | The Japanese journal of antibiotics 20080401 |
| Pharmacokinetic and pharmacodynamic properties of biapenem, a carbapenem antibiotic, in rat experimental model of severe acute pancreatitis. | Pancreas 20080301 |
| Pharmacokinetic modeling and dosage adaptation of biapenem in Japanese patients during continuous venovenous hemodiafiltration. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20080201 |
| Pharmacokinetic-pharmacodynamic target attainment analysis of biapenem in adult patients: a dosing strategy. | Chemotherapy 20080101 |
| [Analysis on the effective dosage regimens for meropenem, biapenem and doripenem against P. aeruginosa infection based on pharmacokinetics and pharmacodynamics theory]. | The Japanese journal of antibiotics 20071201 |
| Protonation state and substrate binding to B2 metallo-beta-lactamase CphA from Aeromonas hydrofila. | Proteins 20071115 |
| [Comparison of ciprofloxacin with biapenem in patients with moderate or severe pneumonia]. | Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 20070501 |
| [Clinical evaluation of biapenem for febrile neutropenia in patients with hematological disorders]. | The Japanese journal of antibiotics 20070401 |
| A simple and rapid determination of biapenem in plasma by high-performance liquid chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20061121 |
| [Antimicrobial susceptibility of Pseudomonas aeruginosa isolated from urine at one hospital to mainly carbapenem and fluoroquinolone drugs]. | The Japanese journal of antibiotics 20060401 |
| Catalytic mechanism of class B2 metallo-beta-lactamase. | The Journal of biological chemistry 20060331 |
| [The combination effects of antibacterial agents against clinical isolated multiple-drug resistant Pseudomonas aeruginosa]. | The Japanese journal of antibiotics 20060201 |
| Antibiotic binding to monozinc CphA beta-lactamase from Aeromonas hydropila: quantum mechanical/molecular mechanical and density functional theory studies. | Journal of medicinal chemistry 20051020 |
| Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. | Journal of pharmaceutical sciences 20050701 |
| A metallo-beta-lactamase enzyme in action: crystal structures of the monozinc carbapenemase CphA and its complex with biapenem. | Journal of molecular biology 20050128 |
| Role for rpoS gene of Pseudomonas aeruginosa in antibiotic tolerance. | FEMS microbiology letters 20050101 |
| [Combined effects of arbekacin with biapenem against in vitro and in vivo model of a mixture of MRSA and Pseudomonas aeruginosa]. | The Japanese journal of antibiotics 20040601 |
| Optimization of dose and dose regimen of biapenem based on pharmacokinetic and pharmacodynamic analysis. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20040401 |
| Optimization of dose and dose regimen of biapenem based on pharmacokinetic and pharmacodynamic analysis. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20040401 |
| [Proper use of carbapenem antibiotics based on the feature in the treatment of infectious diseases (discussion)]]. | The Japanese journal of antibiotics 20040201 |
| Noncognitive symptoms and long-term treatment expectations for Alzheimer disease. | Alzheimer disease and associated disorders 20040101 |
| [Clinical evaluation on biapenem for respiratory infections in elderly patients: safety for renal function]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20030701 |
| [Antibacterial activity of biapenem against recent clinical isolates]. | The Japanese journal of antibiotics 20030401 |
| [Bactericidal activity of biapenem against various efflux system mutants of Pseudomonas aeruginosa]. | The Japanese journal of antibiotics 20020201 |
| Biapenem. | Drugs 20020101 |
| [Bactericidal activity of biapenem against various bacteria]. | The Japanese journal of antibiotics 20011201 |
| [Comparative antibacterial activity of carbapenems against P. aeruginosa (1)]. | The Japanese journal of antibiotics 20011101 |
| [Antimicrobial activities of carbapenems and fourth generation cephems against clinically isolated strains]. | The Japanese journal of antibiotics 20010901 |
| Correlation between in vitro and in vivo models of proconvulsive activity with the carbapenem antibiotics, biapenem, imipenem/cilastatin and meropenem. | Toxicology letters 19950401 |