Structural influence of isothiocyanates on expression of cytochrome P450, phase II enzymes, and activation of Nrf2 in primary rat hepatocytes.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120801

Identifying and characterizing binding sites on the irreversible inhibition of human glutathione S-transferase P1-1 by S-thiocarbamoylation.

Chembiochem : a European journal of chemical biology 20120723

Enhancement of cisplatin cytotoxicity by benzyl isothiocyanate in HL-60 cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20120701

Contact and fumigant toxicity of Armoracia rusticana essential oil, allyl isothiocyanate and related compounds to Dermatophagoides farinae.

Pest management science 20120501

Molecular and life-history effects of a natural toxin on herbivorous and non-target soil arthropods.

Ecotoxicology (London, England) 20120501

First study on antimicriobial activity and synergy between isothiocyanates and antibiotics against selected Gram-negative and Gram-positive pathogenic bacteria from clinical and animal source.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20120501

Optimized labeling of NOTA-conjugated octreotide with F-18.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120401

Content determination of benzyl glucosinolate and anti-cancer activity of its hydrolysis product in Carica papaya L.

Asian Pacific journal of tropical medicine 20120301

3-Benzyl-6-methyl-2-sulfanylidene-2,3-di-hydroquinazolin-4(1H)-one.

Acta crystallographica. Section E, Structure reports online 20120301

Cytotoxicity of benzyl isothiocyanate in normal renal proximal tubular cells and its modulation by glutathione.

Journal of agricultural and food chemistry 20120222

Benzyl isothiocyanate (BITC) induces G2/M phase arrest and apoptosis in human melanoma A375.S2 cells through reactive oxygen species (ROS) and both mitochondria-dependent and death receptor-mediated multiple signaling pathways.

Journal of agricultural and food chemistry 20120118

Varied response of Spodoptera littoralis against Arabidopsis thaliana with metabolically engineered glucosinolate profiles.

Plant physiology and biochemistry : PPB 20120101

Benzyl isothiocyanate inhibits basal and hepatocyte growth factor-stimulated migration of breast cancer cells.

Molecular and cellular biochemistry 20120101

The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes.

Journal of oncology 20120101

Diindolylmethane suppresses ovarian cancer growth and potentiates the effect of cisplatin in tumor mouse model by targeting signal transducer and activator of transcription 3 (STAT3).

BMC medicine 20120101

α-Tocopherol sensitizes human leukemia HL-60 cells to apoptosis induced by benzyl isothiocyanate.

Bioscience, biotechnology, and biochemistry 20120101

Dual-wavelength imaging of tumor progression by activatable and targeting near-infrared fluorescent probes in a bioluminescent breast cancer model.

PloS one 20120101

Critical role of p53 upregulated modulator of apoptosis in benzyl isothiocyanate-induced apoptotic cell death.

PloS one 20120101

Herbivory by a Phloem-feeding insect inhibits floral volatile production.

PloS one 20120101

Benzyl isothiocyanate causes FoxO1-mediated autophagic death in human breast cancer cells.

PloS one 20120101

Antimicrobial activities of isothiocyanates against Campylobacter jejuni isolates.

Frontiers in cellular and infection microbiology 20120101

Nanoemulsions of cancer chemopreventive agent benzyl isothiocyanate display enhanced solubility, dissolution, and permeability.

Journal of agricultural and food chemistry 20111214

Mitogen-activated protein kinase mediates the apoptosis of highly metastatic human non-small cell lung cancer cells induced by isothiocyanates.

The British journal of nutrition 20111201

Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation by inducing apoptosis.

International journal of molecular medicine 20111201

Radiolabeled CCK/gastrin peptides for imaging and therapy of CCK2 receptor-expressing tumors.

Amino acids 20111101

Oral administration of benzyl-isothiocyanate inhibits solid tumor growth and lung metastasis of 4T1 murine mammary carcinoma cells in BALB/c mice.

Breast cancer research and treatment 20111101

Characteristics of papaya seed oils obtained by extrusion-expelling processes.

Journal of the science of food and agriculture 20111001

Phenethyl isothiocyanate sensitizes human cervical cancer cells to apoptosis induced by cisplatin.

Molecular nutrition & food research 20111001

Dietary isothiocyanate-induced apoptosis via thiol modification of DNA topoisomerase IIα.

The Journal of biological chemistry 20110923

Engineering GST M2-2 for high activity with indene 1,2-oxide and indication of an H-site residue sustaining catalytic promiscuity.

Journal of molecular biology 20110909

Benzyl isothiocyanate (BITC) and phenethyl isothiocyanate (PEITC)-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of caspase-3, mitochondria dysfunction and nitric oxide (NO) in human osteogenic sarcoma U-2 OS cells.

Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20110801

Assessment of the protective effects of selected dietary anticarcinogens against DNA damage and cytogenetic effects induced by benzo[a]pyrene in C57BL/6J mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801

Synthesis and antiproliferative activity of novel α- and β-dialkoxyphosphoryl isothiocyanates.

Bioorganic & medicinal chemistry letters 20110801

In vitro and in vivo antifungal activity of synthetic pure isothiocyanates against Sclerotinia sclerotiorum.

Pest management science 20110701

Benzyl isothiocyanate inhibits epithelial-mesenchymal transition in cultured and xenografted human breast cancer cells.

Cancer prevention research (Philadelphia, Pa.) 20110701

The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics.

Chemico-biological interactions 20110630

Benzyl isothiocyanate (BITC) inhibits migration and invasion of human gastric cancer AGS cells via suppressing ERK signal pathways.

Human & experimental toxicology 20110401

Structural requirements for mutation formation from polycyclic aromatic hydrocarbon dihydrodiol epoxides in their interaction with food chemopreventive compounds.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110401

Pancreatic tumor suppression by benzyl isothiocyanate is associated with inhibition of PI3K/AKT/FOXO pathway.

Clinical cancer research : an official journal of the American Association for Cancer Research 20110401

Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways.

Cell death & disease 20110401

Benzyl isothiocyanate inhibits oncogenic actions of leptin in human breast cancer cells by suppressing activation of signal transducer and activator of transcription 3.

Carcinogenesis 20110301

The roles of AIF and Endo G in the apoptotic effects of benzyl isothiocyanate on DU 145 human prostate cancer cells via the mitochondrial signaling pathway.

International journal of oncology 20110301

Selective depletion of mutant p53 by cancer chemopreventive isothiocyanates and their structure-activity relationships.

Journal of medicinal chemistry 20110210

Isothiocyanates inhibit proteasome activity and proliferation of multiple myeloma cells.

Carcinogenesis 20110201

MicroRNA-375 and MicroRNA-221: Potential Noncoding RNAs Associated with Antiproliferative Activity of Benzyl Isothiocyanate in Pancreatic Cancer.

Genes & cancer 20110201

Effectiveness of different solid-phase microextraction fibres for differentiation of selected Madeira island fruits based on their volatile metabolite profile--identification of novel compounds.

Talanta 20110115

Dietary phenethyl isothiocyanate alters gene expression in human breast cancer cells.

Evidence-based complementary and alternative medicine : eCAM 20110101

Medicinal plants used as antitumor agents in Brazil: an ethnobotanical approach.

Evidence-based complementary and alternative medicine : eCAM 20110101

Role of mitochondrial electron transport chain complexes in capsaicin mediated oxidative stress leading to apoptosis in pancreatic cancer cells.

PloS one 20110101

Honokiol arrests cell cycle, induces apoptosis, and potentiates the cytotoxic effect of gemcitabine in human pancreatic cancer cells.

PloS one 20110101

Inhibition of lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression by 4-[(2'-O-acetyl-α-L-rhamnosyloxy)benzyl]isothiocyanate from Moringa oleifera.

Nutrition and cancer 20110101

Benzyl isothiocyanate, a major component from the roots of Salvadora persica is highly active against Gram-negative bacteria.

PloS one 20110101

Dietary fat increases solid tumor growth and metastasis of 4T1 murine mammary carcinoma cells and mortality in obesity-resistant BALB/c mice.

Breast cancer research : BCR 20110101

Resveratrol inhibits growth of orthotopic pancreatic tumors through activation of FOXO transcription factors.

PloS one 20110101

Benzyl isothiocyanate suppresses pancreatic tumor angiogenesis and invasion by inhibiting HIF-α/VEGF/Rho-GTPases: pivotal role of STAT-3.

PloS one 20110101

Notch activation by phenethyl isothiocyanate attenuates its inhibitory effect on prostate cancer cell migration.

PloS one 20110101

Antiplasmodial Properties and Bioassay-Guided Fractionation of Ethyl Acetate Extracts from Carica papaya Leaves.

Journal of parasitology research 20110101

Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells.

Clinical epigenetics 20110101

Glutathione s-transferases in pediatric cancer.

Frontiers in oncology 20110101

Phytochemical and antifungal profiles of the seeds of carica papaya L.

Indian journal of pharmaceutical sciences 20110101

Determination of new biomarkers to monitor the dietary consumption of isothiocyanates.

Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20101201

Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Bioorganic & medicinal chemistry letters 20101101

Analogues of morphanthridine and the tear gas dibenz[b,f][1,4]oxazepine (CR) as extremely potent activators of the human transient receptor potential ankyrin 1 (TRPA1) channel.

Journal of medicinal chemistry 20101014

Trypanocidal and antileukaemic effects of the essential oils of Hagenia abyssinica, Leonotis ocymifolia, Moringa stenopetala, and their main individual constituents.

Phytomedicine : international journal of phytotherapy and phytopharmacology 20101001

Evaluation of antibacterial activity of 3-butenyl, 4-pentenyl, 2-phenylethyl, and benzyl isothiocyanate in Brassica vegetables.

Journal of food science 20100901

Candidate dietary phytochemicals modulate expression of phase II enzymes GSTP1 and NQO1 in human lung cells.

The Journal of nutrition 20100801

Transient receptor potential ankyrin 1 (TRPA1) channel as emerging target for novel analgesics and anti-inflammatory agents.

Journal of medicinal chemistry 20100722

Benzyl isothiocyanate-mediated inhibition of histone deacetylase leads to NF-kappaB turnoff in human pancreatic carcinoma cells.

Molecular cancer therapeutics 20100601

p53-Independent apoptosis by benzyl isothiocyanate in human breast cancer cells is mediated by suppression of XIAP expression.

Cancer prevention research (Philadelphia, Pa.) 20100601

Inhibition of human breast cancer xenograft growth by cruciferous vegetable constituent benzyl isothiocyanate.

Molecular carcinogenesis 20100501

Antimicrobial activity of phenolics and glucosinolate hydrolysis products and their synergy with streptomycin against pathogenic bacteria.

Medicinal chemistry (Shariqah (United Arab Emirates)) 20100501

New biomarkers for monitoring the levels of isothiocyanates in humans.

Chemical research in toxicology 20100419

Enhanced Nrf2-dependent induction of glutathione in mouse embryonic fibroblasts by isoselenocyanate analog of sulforaphane.

Bioorganic & medicinal chemistry letters 20100415

Phytochemicals in cancer prevention and therapy: truth or dare?

Toxins 20100401

Benzyl isothiocyanate (BITC) inhibits migration and invasion of human colon cancer HT29 cells by inhibiting matrix metalloproteinase-2/-9 and urokinase plasminogen (uPA) through PKC and MAPK signaling pathway.

Journal of agricultural and food chemistry 20100310

Chloroplastic phosphoadenosine phosphosulfate metabolism regulates basal levels of the prohormone jasmonic acid in Arabidopsis leaves.

Plant physiology 20100301

The toxic effects of benzyl glucosinolate and its hydrolysis product, the biofumigant benzyl isothiocyanate, to Folsomia fimetaria.

Environmental toxicology and chemistry 20100201

Immunochemical detection of food-derived isothiocyanate as a lysine conjugate.

Bioscience, biotechnology, and biochemistry 20100101

Cruciferous vegetable intake is inversely associated with lung cancer risk among smokers: a case-control study.

BMC cancer 20100101

Isothiocyanates induce oxidative stress and suppress the metastasis potential of human non-small cell lung cancer cells.

BMC cancer 20100101

Molecular and cellular designs of insect taste receptor system.

Frontiers in cellular neuroscience 20100101

Inhibition of PI3K/AKT and MAPK/ERK pathways causes activation of FOXO transcription factor, leading to cell cycle arrest and apoptosis in pancreatic cancer.

Journal of molecular signaling 20100101

Ethnopharmacological survey among migrants living in the Southeast Atlantic Forest of Diadema, São Paulo, Brazil.

Journal of ethnobiology and ethnomedicine 20100101

Salvadora persica.

Pharmacognosy reviews 20100101

Prevention of mammary carcinogenesis in MMTV-neu mice by cruciferous vegetable constituent benzyl isothiocyanate.

Cancer research 20091215

Benzyl isothiocyanate exhibits anti-inflammatory effects in murine macrophages and in mouse skin.

Journal of molecular medicine (Berlin, Germany) 20091201

[Antimicrobial efficacy of benzyl isothiocyanate].

Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20091201

Benzyl isothiocyanate inhibits murine WEHI-3 leukemia cells in vitro and promotes phagocytosis in BALB/c mice in vivo.

Leukemia research 20091101

A new class of isothiocyanate-based irreversible inhibitors of macrophage migration inhibitory factor.

Biochemistry 20091020

Aggresome-like structure induced by isothiocyanates is novel proteasome-dependent degradation machinery.

Biochemical and biophysical research communications 20091016

Benzyl isothiocyanate-mediated generation of reactive oxygen species causes cell cycle arrest and induces apoptosis via activation of MAPK in human pancreatic cancer cells.

Carcinogenesis 20091001

Growth-inhibiting activities of phenethyl isothiocyanate and its derivatives against intestinal bacteria.

Journal of food science 20091001

Anti-proliferative and proapoptotic effects of benzyl isothiocyanate on human pancreatic cancer cells is linked to death receptor activation and RasGAP/Rac1 down-modulation.

International journal of oncology 20090901

Diverse chemicals including aryl hydrocarbon receptor ligands modulate transcriptional activity of the 3'immunoglobulin heavy chain regulatory region.

Toxicology 20090630

Cancer preventive isothiocyanates induce selective degradation of cellular alpha- and beta-tubulins by proteasomes.

The Journal of biological chemistry 20090619

Re: The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.

Journal of the National Cancer Institute 20090616

Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents.

Toxicology and applied pharmacology 20090615

Degradation and sorption of 2-propenyl and benzyl isothiocyanate in soil.

Environmental toxicology and chemistry 20090601

Potency of isothiocyanates to induce luciferase reporter gene expression via the electrophile-responsive element from murine glutathione S-transferase Ya.

Toxicology in vitro : an international journal published in association with BIBRA 20090601

The antimicrobial effects of glucosinolates and their respective enzymatic hydrolysis products on bacteria isolated from the human intestinal tract.

Journal of applied microbiology 20090601

Benzyl isothiocyanate sensitizes human pancreatic cancer cells to radiation therapy.

Frontiers in bioscience (Elite edition) 20090601

Activation of ATM/Chk1 by curcumin causes cell cycle arrest and apoptosis in human pancreatic cancer cells.

British journal of cancer 20090505

Enzyme activities and subcellular localization of members of the Arabidopsis glutathione transferase superfamily.

Journal of experimental botany 20090301

The role of STAT-3 in the induction of apoptosis in pancreatic cancer cells by benzyl isothiocyanate.

Journal of the National Cancer Institute 20090204

Aurintricarboxylic acid inhibits influenza virus neuraminidase.

Antiviral research 20090201

Isothiocyanates repress estrogen receptor alpha expression in breast cancer cells.

Oncology reports 20090101

Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L.

Foodborne pathogens and disease 20090101

Phytochemical induction of cell cycle arrest by glutathione oxidation and reversal by N-acetylcysteine in human colon carcinoma cells.

Nutrition and cancer 20090101

Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells.

Cancer cell international 20090101

Differing mechanisms of simple nitrile formation on glucosinolate degradation in Lepidium sativum and Nasturtium officinale seeds.

Phytochemistry 20090101

(-)-Epigallocatechin-3-gallate potentiates the cytotoxicity induced by benzyl isothiocyanate and hydrogen peroxide in human Jurkat T lymphocytes.

Bioscience, biotechnology, and biochemistry 20081101

Inhibitory effect of fermented papaya preparation on hydroxyl radical generation from methylguanidine.

Journal of clinical biochemistry and nutrition 20081101

Benzyl isothiocyanate targets mitochondrial respiratory chain to trigger reactive oxygen species-dependent apoptosis in human breast cancer cells.

The Journal of biological chemistry 20081031

Benzylglucosinolate, benzylisothiocyanate, and myrosinase activity in papaya fruit during development and ripening.

Journal of agricultural and food chemistry 20081022

Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles.

Proceedings of the National Academy of Sciences of the United States of America 20081014

ATP depletion alters the mode of cell death induced by benzyl isothiocyanate.

Biochimica et biophysica acta 20081001

Dietary isothiocyanate mediated apoptosis of human cancer cells is associated with Bcl-xL phosphorylation.

International journal of oncology 20081001

Cancer is a preventable disease that requires major lifestyle changes.

Pharmaceutical research 20080901

Suppressive Effects of Selected Food Phytochemicals on CD74 Expression in NCI-N87 Gastric Carcinoma Cells.

Journal of clinical biochemistry and nutrition 20080901

Benzyl isothiocyanate inhibits metalloproteinase-2/-9 expression by suppressing the mitogen-activated protein kinase in SK-Hep1 human hepatoma cells.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080701

Herbal compounds and toxins modulating TRP channels.

Current neuropharmacology 20080301

Etoposide induces ATM-dependent mitochondrial biogenesis through AMPK activation.

PloS one 20080101

Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate.

PloS one 20080101

Triphala inhibits both in vitro and in vivo xenograft growth of pancreatic tumor cells by inducing apoptosis.

BMC cancer 20080101

Binding to protein by isothiocyanates: a potential mechanism for apoptosis induction in human non small lung cancer cells.

Nutrition and cancer 20080101

Modifying effects of dietary factors on (-)-epigallocatechin-3-gallate-induced pro-matrix metalloproteinase-7 production in HT-29 human colorectal cancer cells.

Bioscience, biotechnology, and biochemistry 20071001

Glutathione- and thioredoxin-related enzymes are modulated by sulfur-containing chemopreventive agents.

Biological chemistry 20071001

Formation and degradation kinetics of the biofumigant benzyl isothiocyanate in soil.

Environmental science & technology 20070615

Papaya seed represents a rich source of biologically active isothiocyanate.

Journal of agricultural and food chemistry 20070530

Selective cytotoxicity of benzyl isothiocyanate in the proliferating fibroblastoid cells.

International journal of cancer 20070201

Lipid peroxidation, oxidative stress genes and dietary factors in breast cancer protection: a hypothesis.

Breast cancer research : BCR 20070101

Comments regarding: Benzyl isothiocyanate (BITC) induces apoptosis in ovarian cancer cells in vitro Kalkunte S, Swamy N, Dizon DS, Brard L. J Exp Ther Oncol.5(4):287-300, 2006.

Journal of experimental therapeutics & oncology 20070101

p38MAPK mediates benzyl isothiocyanate-induced p21WAF1 expression in vascular smooth muscle cells via the regulation of Sp1.

Biochemical and biophysical research communications 20061124

Benzyl isothiocyanate-induced apoptosis in human breast cancer cells is initiated by reactive oxygen species and regulated by Bax and Bak.

Molecular cancer therapeutics 20061101

Protective effects of benzyl isothiocyanate and sulforaphane but not resveratrol against initiation of pancreatic carcinogenesis in hamsters.

Cancer letters 20060928

Characterization of two Arabidopsis thaliana glutathione S-transferases.

Plant cell reports 20060901

Newly constructed stable reporter cell lines for mechanistic studies on electrophile-responsive element-mediated gene expression reveal a role for flavonoid planarity.

Biochemical pharmacology 20060714

Haplotype-environment interactions that regulate the human glutathione S-transferase P1 promoter.

Cancer research 20060615

Raphanus sativus and its isothiocyanates inhibit vascular smooth muscle cells proliferation and induce G(1) cell cycle arrest.

International immunopharmacology 20060501

Invasive plant suppresses the growth of native tree seedlings by disrupting belowground mutualisms.

PLoS biology 20060501

Effects of benzyl and phenethyl isothiocyanate on P450s 2A6 and 2A13: potential for chemoprevention in smokers.

Carcinogenesis 20060401

Effect of isothiocyanates on nuclear accumulation of NF-kappaB, Nrf2, and thioredoxin in caco-2 cells.

Journal of agricultural and food chemistry 20060308

The principal urinary metabolites of dietary isothiocyanates, N-acetylcysteine conjugates, elicit the same anti-proliferative response as their parent compounds in human bladder cancer cells.

Anti-cancer drugs 20060301

Cell death induction by isothiocyanates and their underlying molecular mechanisms.

BioFactors (Oxford, England) 20060101

Benzyl isothiocyanate (BITC) induces apoptosis in ovarian cancer cells in vitro.

Journal of experimental therapeutics & oncology 20060101

Dietary isothiocyanates modify mitochondrial functions through their electrophilic reaction.

Bioscience, biotechnology, and biochemistry 20051201

Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.

Current drug metabolism 20051001

The role of c-Jun in the AP-1 activation induced by naturally occurring isothiocyanates.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050901

Modulation of jejunal contractions by extract of Carica papaya L. seeds.

Phytotherapy research : PTR 20050701

A novel function of benzyl isothiocyanate in vascular smooth muscle cells: the role of ERK1/2, cell cycle regulation, and matrix metalloproteinase-9.

Journal of cellular physiology 20050601

The identification of 1,3-oxazolidine-2-thiones and 1,3-thiazolidine-2-thiones from the reaction of glucose with benzyl isothiocyanate.

Carbohydrate research 20050207

Glutathione S-transferase Pi has at least three distinguishable xenobiotic substrate sites close to its glutathione-binding site.

The Journal of biological chemistry 20041126

Identification and characterization of a Pi isoform of glutathione S-transferase (GSTP1) as a zeaxanthin-binding protein in the macula of the human eye.

The Journal of biological chemistry 20041119

Targeting of a head and neck squamous cell carcinoma xenograft model using the chimeric monoclonal antibody U36 radioiodinated with a closo-dodecaborate-containing linker.

Acta oto-laryngologica 20041101

Structure-activity relationship of S-benzylisothiourea derivatives to induce spherical cells in Escherichia coli.

Bioscience, biotechnology, and biochemistry 20041101

Do aberrant crypt foci have predictive value for the occurrence of colorectal tumours? Potential of gene expression profiling in tumours.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041001

Induction of apoptosis in a non-small cell human lung cancer cell line by isothiocyanates is associated with P53 and P21.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20041001

Cell cycle arrest, apoptosis induction and inhibition of nuclear factor kappa B activation in anti-proliferative activity of benzyl isothiocyanate against human pancreatic cancer cells.

Carcinogenesis 20040901

Dietary organic isothiocyanates are cytotoxic in human breast cancer MCF-7 and mammary epithelial MCF-12A cell lines.

Experimental biology and medicine (Maywood, N.J.) 20040901

Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040801

Effects of benzyl-, phenethyl-, and alpha-naphthyl isothiocyanates on P-glycoprotein- and MRP1-mediated transport.

Journal of pharmaceutical sciences 20040701

Selective inhibition of CYP2B6-catalyzed bupropion hydroxylation in human liver microsomes in vitro.

Drug metabolism and disposition: the biological fate of chemicals 20040601

Effect of benzyl isothiocyanate on spontaneous and induced force of rat uterine contraction.

Pharmacological research 20040501

Pregnancy outcomes following pre- and post-implantation exposure of Sprague-Dawley rats to benzyl isothiocyanate.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040501

Benzyl isothiocyanate inhibits excessive superoxide generation in inflammatory leukocytes: implication for prevention against inflammation-related carcinogenesis.

Carcinogenesis 20040401

A link between benzyl isothiocyanate-induced cell cycle arrest and apoptosis: involvement of mitogen-activated protein kinases in the Bcl-2 phosphorylation.

Cancer research 20040315

In vitro digestion of sinigrin and glucotropaeolin by single strains of Bifidobacterium and identification of the digestive products.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040301

Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.

Environmental and molecular mutagenesis 20040101

Benzyl isothiocyanate modifies expression of the G2/M arrest-related genes.

BioFactors (Oxford, England) 20040101

Benzyl isothiocyanate inhibits oxidative stress in mouse skin: Involvement of attenuation of leukocyte infiltration.

BioFactors (Oxford, England) 20040101

Tocolytic and toxic activity of papaya seed extract on isolated rat uterus.

Life sciences 20031219

Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl)nitrosamine in rats after initiation.

Cancer science 20031101

Requirement of a carbon spacer in benzyl isothiocyanate-mediated cytotoxicity and MAPK activation in head and neck squamous cell carcinoma.

Carcinogenesis 20031001

Influence of plant and bacterial myrosinase activity on the metabolic fate of glucosinolates in gnotobiotic rats.

The British journal of nutrition 20030801

Naturally occurring Phe151Leu substitution near a conserved folding module lowers stability of glutathione transferase P1-1.

Biochimica et biophysica acta 20030626

Effects of selected food factors with chemopreventive properties on combined lipopolysaccharide- and interferon-gamma-induced IkappaB degradation in RAW264.7 macrophages.

Cancer letters 20030530

Determination of amino acids in foods by reversed-phase HPLC with new precolumn derivatives, butylthiocarbamyl, and benzylthiocarbamyl derivatives compared to the phenylthiocarbamyl derivative and ion exchange chromatography.

Molecular biotechnology 20030501

Effects of benzyl isothiocyanate and 2-phenethyl isothiocyanate on benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism in F-344 rats.

Carcinogenesis 20030301

Effects of garden and water cress juices and their constituents, benzyl and phenethyl isothiocyanates, towards benzo(a)pyrene-induced DNA damage: a model study with the single cell gel electrophoresis/Hep G2 assay.

Chemico-biological interactions 20030106

Enhancement of glutathione and g-glutamylcysteine synthetase, the rate limiting enzyme of glutathione synthesis, by chemoprotective plant-derived food and beverage components in the human hepatoma cell line HepG2.

Nutrition and cancer 20030101

Involvement of toxicity as an early event in urinary bladder carcinogenesis induced by phenethyl isothiocyanate, benzyl isothiocyanate, and analogues in F344 rats.

Toxicologic pathology 20030101

Benzyl isothiocyanate: an effective inhibitor of polycyclic aromatic hydrocarbon tumorigenesis in A/J mouse lung.

Cancer letters 20021210

Effect of organic isothiocyanates on the P-glycoprotein- and MRP1-mediated transport of daunomycin and vinblastine.

Pharmaceutical research 20021001

Investigation of the tuber constituents of maca (Lepidium meyenii Walp.).

Journal of agricultural and food chemistry 20020925

Effects of benzyl isothiocyanate and phenethyl isothiocyanate on DNA adduct formation by a mixture of benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung.

Carcinogenesis 20020901

Chemoprotective effects of garden cress (Lepidium sativum) and its constituents towards 2-amino-3-methyl-imidazo[4,5-f]quinoline (IQ)-induced genotoxic effects and colonic preneoplastic lesions.

Carcinogenesis 20020701

Effects of papaya seed extract and benzyl isothiocyanate on vascular contraction.

Life sciences 20020621

Effect of naturally occurring organosulfur compounds on nitric oxide production in lipopolysaccharide-activated macrophages.

Life sciences 20020614

Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis.

The Journal of biological chemistry 20020308

Palladium(0)-catalyzed enantioselective O,S-rearrangement of racemic O-allylic thiocarbamates: a new entry to enantioenriched allylic sulfur compounds.

The Journal of organic chemistry 20020222

Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis.

Cancer research 20020101

Pyridazine derivatives and related compounds, part 9. tetrazolo[1,5-b]pyridazine-8-carbohydrazide: synthesis and some reactions.

Bollettino chimico farmaceutico 20020101

Simultaneous treatment with benzyl isothiocyanate, a strong bladder promoter, inhibits rat urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.

Nutrition and cancer 20020101

4-(Methylthio)-3-butenyl isothiocyanate, a principal antimutagen in daikon (Raphanus sativus; Japanese white radish).

Journal of agricultural and food chemistry 20011201

Decomposition rates of isothiocyanate conjugates determine their activity as inhibitors of cytochrome p450 enzymes.

Chemical research in toxicology 20010901

Dietary indoles and isothiocyanates that are generated from cruciferous vegetables can both stimulate apoptosis and confer protection against DNA damage in human colon cell lines.

Cancer research 20010815

Differential effects of naturally occurring isothiocyanates on the activities of cytochrome P450 2E1 and the mutant P450 2E1 T303A.

Archives of biochemistry and biophysics 20010701

Benzyl isothiocyanate is the chief or sole anthelmintic in papaya seed extracts.

Phytochemistry 20010601

Effects of benzyl isothiocyanate on rat and human cytochromes P450: identification of metabolites formed by P450 2B1.

The Journal of pharmacology and experimental therapeutics 20010101

Toxic effects of benzyl and allyl isothiocyanates and benzyl-isoform specific metabolites in the urinary bladder after a single intravesical application to rats.

Toxicologic pathology 20010101

Increased bioactivation of dihaloalkanes in rat liver due to induction of class theta glutathione S-transferase T1-1.

The Biochemical journal 19981101

Chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity.

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