9H-Pyrido[3,4-b]indole
Title | Journal |
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Indoleamine 2,3-dioxygenase 1 (IDO1) inhibitors activate the aryl hydrocarbon receptor. | Toxicology and applied pharmacology 20170515 |
Monoamine oxidase inhibitory activity in tobacco particulate matter: Are harman and norharman the only physiologically relevant inhibitors? | Neurotoxicology 20170301 |
Inhibition of the aryl hydrocarbon receptor prevents Western diet-induced obesity. Model for AHR activation by kynurenine via oxidized-LDL, TLR2/4, TGFβ, and IDO1. | Toxicology and applied pharmacology 20160601 |
Content of heterocyclic amines and polycyclic aromatic hydrocarbons in pork, beef and chicken barbecued at home by Danish consumers. | Meat science 20130101 |
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. | Bioorganic & medicinal chemistry 20121115 |
Antioxidant capacity and inhibitory effect of grape seed and rosemary extract in marinades on the formation of heterocyclic amines in fried beef patties. | Food chemistry 20120915 |
Detection of bioactive exometabolites produced by the filamentous marine cyanobacterium Geitlerinema sp. | Marine biotechnology (New York, N.Y.) 20120801 |
Beta-carboline alkaloids derived from the ascidian Synoicum sp. | Bioorganic & medicinal chemistry 20120701 |
6-Meth-oxy-1-(4-meth-oxy-phen-yl)-1,2,3,4-tetra-hydro-9H-β-carbolin-2-ium acetate. | Acta crystallographica. Section E, Structure reports online 20120501 |
Charged behaviour from neutral ligands: synthesis and properties of N-heterocyclic pseudo-amides. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120402 |
Bis(6-meth-oxy-1-methyl-2,3,4,9-tetra-hydro-1H-β-carbolin-2-ium) tetra-chloridozincate(II) dihydrate. | Acta crystallographica. Section E, Structure reports online 20120401 |
Structure-activity relationship study of beta-carboline derivatives as haspin kinase inhibitors. | Bioorganic & medicinal chemistry letters 20120301 |
Effects of apomorphine and β-carbolines on firing rate of neurons in the ventral pallidum in the rats. | Behavioural brain research 20120201 |
Novel indoleamine 2,3-dioxygenase-1 inhibitors from a multistep in silico screen. | Bioorganic & medicinal chemistry 20120201 |
Vitamin e supplementation with rauwolfia vomitoria root bark extract improves hematological indices. | North American journal of medical sciences 20120201 |
Administration of harmine and imipramine alters creatine kinase and mitochondrial respiratory chain activities in the rat brain. | Depression research and treatment 20120101 |
New acetylcholinesterase inhibitors for Alzheimer's disease. | International journal of Alzheimer's disease 20120101 |
The role of circulating serotonin in the development of chronic obstructive pulmonary disease. | PloS one 20120101 |
Tacrine-6-ferulic acid, a novel multifunctional dimer, inhibits amyloid-β-mediated Alzheimer's disease-associated pathogenesis in vitro and in vivo. | PloS one 20120101 |
Alpha7 nicotinic acetylcholine receptor is a target in pharmacology and toxicology. | International journal of molecular sciences 20120101 |
Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents. | Frontiers in microbiology 20120101 |
JKA97, a novel benzylidene analog of harmine, exerts anti-cancer effects by inducing G1 arrest, apoptosis, and p53-independent up-regulation of p21. | PloS one 20120101 |
Mouse models of Down syndrome as a tool to unravel the causes of mental disabilities. | Neural plasticity 20120101 |
Intracerebral injection of low amounts of norharman induces moderate Parkinsonism-like behavioral symptoms in rat. | Neurotoxicology and teratology 20120101 |
Formation of heterocyclic amines during cooking of duck meat. | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101 |
A series of beta-carboline derivatives inhibit the kinase activity of PLKs. | PloS one 20120101 |
Molecular insights into human monoamine oxidase (MAO) inhibition by 1,4-naphthoquinone: evidences for menadione (vitamin K3) acting as a competitive and reversible inhibitor of MAO. | Bioorganic & medicinal chemistry 20111215 |
Beta-carboline-3-carboxamide derivatives as promising antileishmanial agents. | Annals of tropical medicine and parasitology 20111201 |
Molecular analysis and structure-activity relationship modeling of the substrate/inhibitor interaction site of plasma membrane monoamine transporter. | The Journal of pharmacology and experimental therapeutics 20111101 |
Synthesis, structures, cellular uptake and apoptosis-inducing properties of highly cytotoxic ruthenium-Norharman complexes. | Dalton transactions (Cambridge, England : 2003) 20110914 |
The Arabidopsis phi class glutathione transferase AtGSTF2: binding and regulation by biologically active heterocyclic ligands. | The Biochemical journal 20110815 |
Inhibition of the bioactivation of the neurotoxin MPTP by antioxidants, redox agents and monoamine oxidase inhibitors. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801 |
[Simultaneous determination of 9 heterocyclic aromatic amine in poultry products by solid-phase extraction-high performance liquid chromatography]. | Se pu = Chinese journal of chromatography 20110801 |
In vitro and in vivo activities of Peganum harmala extract against Leishmania major. | Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences 20110801 |
Dietary inhibitors of monoamine oxidase A. | Journal of neural transmission (Vienna, Austria : 1996) 20110701 |
β-Carboline (norharman). | Acta crystallographica. Section C, Crystal structure communications 20110701 |
[Fingerprint research and multi-component quantitative analysis of Kumu injection by HPLC]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20110701 |
Harmine, a natural beta-carboline alkaloid, upregulates astroglial glutamate transporter expression. | Neuropharmacology 20110601 |
The inhibition activity of selected beta-carboline alkaloids on enzymes of acetylcholinesterase and butyrylcholinesterase. | Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20110601 |
SPE/RP-HPLC using C1 columns: an environmentally friendly alternative to conventional reverse-phase separations for quantitation of beta-carboline alkaloids in human serum samples. | Analytical and bioanalytical chemistry 20110401 |
Effects of harmane and other β-carbolines on apomorphine-induced licking behavior in rat. | Pharmacology, biochemistry, and behavior 20110401 |
Screening of non-polar heterocyclic amines in urine by microextraction in packed sorbent-fluorimetric detection and confirmation by capillary liquid chromatography. | Talanta 20110215 |
Indol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors. | Bioorganic & medicinal chemistry 20110215 |
3-benzylamino-β-carboline derivatives induce apoptosis through G2/M arrest in human carcinoma cells HeLa S-3. | European journal of medicinal chemistry 20110201 |
Hazardous compounds in tobacco smoke. | International journal of environmental research and public health 20110201 |
Effects of spider venom toxin PWTX-I (6-Hydroxytrypargine) on the central nervous system of rats. | Toxins 20110201 |
Norharmane: old yet highly selective dual channel ratiometric fluoride and hydrogen sulfate ion sensor. | The Analyst 20110121 |
The biochemical and cellular basis for nutraceutical strategies to attenuate neurodegeneration in Parkinson's disease. | International journal of molecular sciences 20110101 |
Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO). | PloS one 20110101 |
Analysis of additivity and synergism in the anti-plasmodial effect of purified compounds from plant extracts. | Malaria journal 20110101 |
Harmine activates intrinsic and extrinsic pathways of apoptosis in B16F-10 melanoma. | Chinese medicine 20110101 |
Antioxidant activity of beta-carboline derivatives. | Acta poloniae pharmaceutica 20110101 |
Synthesis of 1-substituted carbazolyl-1,2,3,4-tetrahydro- and carbazolyl-3,4-dihydro-β-carboline analogs as potential antitumor agents. | Marine drugs 20110101 |
β-carboline compounds, including harmine, inhibit DYRK1A and tau phosphorylation at multiple Alzheimer's disease-related sites. | PloS one 20110101 |
Antibacterial activity of some selected medicinal plants of Pakistan. | BMC complementary and alternative medicine 20110101 |
Impact of synaptic neurotransmitter concentration time course on the kinetics and pharmacological modulation of inhibitory synaptic currents. | Frontiers in cellular neuroscience 20110101 |
Blood harmane concentrations in 497 individuals relative to coffee, cigarettes, and food consumption on the morning of testing. | Journal of toxicology 20110101 |
Phenobarbital but Not Diazepam Reduces AMPA/kainate Receptor Mediated Currents and Exerts Opposite Actions on Initial Seizures in the Neonatal Rat Hippocampus. | Frontiers in cellular neuroscience 20110101 |
Comparative Effects of α-, β-, and γ-Carbolines on Platelet Aggregation and Lipid Membranes. | Journal of toxicology 20110101 |
Studies on anti-metastatic and anti-invasive effects of harmine using highly metastatic murine B16F-10 melanoma cells. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20110101 |
Chronic Treatment with a Promnesiant GABA-A α5-Selective Inverse Agonist Increases Immediate Early Genes Expression during Memory Processing in Mice and Rectifies Their Expression Levels in a Down Syndrome Mouse Model. | Advances in pharmacological sciences 20110101 |
Kinase inhibitors from marine sponges. | Marine drugs 20110101 |
Recently confirmed apoptosis-inducing lead compounds isolated from marine sponge of potential relevance in cancer treatment. | Marine drugs 20110101 |
Long term exposure to norharman exacerbates 6-hydroxydopamine-induced parkinsonism: possible involvement of L-type Ca2+ channels. | Behavioural brain research 20101220 |
Harmine inhibits tumour specific neo-vessel formation by regulating VEGF, MMP, TIMP and pro-inflammatory mediators both in vivo and in vitro. | European journal of pharmacology 20101215 |
Anti-oxidant and Anti-hypercholesterolemic Activities of Wasabia japonica. | Evidence-based complementary and alternative medicine : eCAM 20101201 |
Beta-carboline alkaloids harmaline and harmalol induce melanogenesis through p38 mitogen-activated protein kinase in B16F10 mouse melanoma cells. | BMB reports 20101201 |
Capillary liquid chromatography with diode array and mass spectrometry detection for heterocyclic aromatic amine determination in ready-to-eat food treated with electron-beam irradiation. | Journal of chromatography. A 20101022 |
Antibacterial and antifungal activities of (beta)-carboline alkaloids of Peganum harmala (L) seeds and their combination effects. | Fitoterapia 20101001 |
Fractionation and identification of organic nitrogen species from bio-oil produced by fast pyrolysis of sewage sludge. | Bioresource technology 20101001 |
Synthesis and bioactivity of beta-carboline derivatives. | Natural product communications 20101001 |
Beta-carboline alkaloids bind DNA. | Journal of photochemistry and photobiology. B, Biology 20100802 |
Regulation of dioxin receptor function by different beta-carboline alkaloids. | Archives of toxicology 20100801 |
Synthesis and evaluation of beta-carboline derivatives as inhibitors of human immunodeficiency virus. | Bioorganic & medicinal chemistry letters 20100801 |
Eudistomidin G, a new beta-carboline alkaloid from the Okinawan marine tunicate Eudistoma glaucus and structure revision of eudistomidin B. | Bioorganic & medicinal chemistry letters 20100715 |
Kinesin spindle protein (KSP) inhibitors with 2,3-fused indole scaffolds. | Journal of medicinal chemistry 20100708 |
Simultaneous determination of six non-polar heterocyclic amines in meat samples by supercritical fluid extraction-capillary electrophoresis under fluorimetric detection. | Electrophoresis 20100701 |
Construction of indole- and isoquinoline-fused nitrogen-containing heterocycles through copper-catalyzed multi-component reaction. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100701 |
Photosensitized cleavage of plasmidic DNA by norharmane, a naturally occurring beta-carboline. | Organic & biomolecular chemistry 20100607 |
Tandem intramolecular photocycloaddition-retro-Mannich fragmentation as a route to spiro[pyrrolidine-3,3'-oxindoles]. Total synthesis of (+/-)-coerulescine, (+/-)-horsfiline, (+/-)-elacomine, and (+/-)-6-deoxyelacomine. | The Journal of organic chemistry 20100604 |
Design, synthesis and 3D-QSAR of beta-carboline derivatives as potent antitumor agents. | European journal of medicinal chemistry 20100601 |
Beta-carboline alkaloids from the stems of Picrasma quassioides. | Magnetic resonance in chemistry : MRC 20100601 |
Bivalent beta-carbolines as potential multitarget anti-Alzheimer agents. | Journal of medicinal chemistry 20100513 |
A class of 3S-2-aminoacyltetrahydro-beta-carboline-3-carboxylic acids: their facile synthesis, inhibition for platelet activation, and high in vivo anti-thrombotic potency. | Journal of medicinal chemistry 20100422 |
Synthesis and cytotoxic evaluation of N2-benzylated quaternary beta-carboline amino acid ester conjugates. | European journal of medicinal chemistry 20100401 |
Electrophysiological characterization of harmane-induced activation of mesolimbic dopamine neurons. | European journal of pharmacology 20100310 |
Electrospray MS-based characterization of beta-carbolines--mutagenic constituents of thermally processed meat. | Molecular nutrition & food research 20100301 |
beta-Carboline alkaloids in Peganum harmala and inhibition of human monoamine oxidase (MAO). | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100301 |
Context dependent benzodiazepine modulation of GABA(A) receptor opening frequency. | Current neuropharmacology 20100301 |
A beta-carboline alkaloid from the Papua New Guinea marine sponge hyrtios reticulatus. | Journal of natural products 20100226 |
The beta-carboline alkaloid harmine inhibits BCRP and can reverse resistance to the anticancer drugs mitoxantrone and camptothecin in breast cancer cells. | Phytotherapy research : PTR 20100101 |
Substituted tetrahydro-beta-carbolines as potential agents for the treatment of human papillomavirus infection. | Bioorganic & medicinal chemistry letters 20100101 |
The effect of eurycoma longifolia Jack on spermatogenesis in estrogen-treated rats. | Clinics (Sao Paulo, Brazil) 20100101 |
Marine drugs from sponge-microbe association--a review. | Marine drugs 20100101 |
Disease resistance in the drywood termite, Incisitermes schwarzi: does nesting ecology affect immunocompetence? | Journal of insect science (Online) 20100101 |
Are known cyanotoxins involved in the toxicity of picoplanktonic and filamentous North Atlantic marine cyanobacteria? | Marine drugs 20100101 |
Investigation into the in vivo effects of five novel tacrine/ferulic acid and beta-carboline derivatives on scopolamine-induced cognitive impairment in rats using radial maze paradigm. | Arzneimittel-Forschung 20100101 |
Beta-carboline alkaloids and essential tremor: exploring the environmental determinants of one of the most prevalent neurological diseases. | TheScientificWorldJournal 20100101 |
Effects of cooking variables on formation of heterocyclic amines (HCA) in roasted pork and mackerel. | Journal of toxicology and environmental health. Part A 20100101 |
Gene expression signature-based screening identifies new broadly effective influenza a antivirals. | PloS one 20100101 |
Antiviral lead compounds from marine sponges. | Marine drugs 20100101 |
Immense essence of excellence: marine microbial bioactive compounds. | Marine drugs 20100101 |
Arylalkylamine-, beta-carboline-, quinolizine- and azecine-derived compounds and their in vitro interaction with the ionotropic 5-HT3 receptor: search for new lead structures. | Arzneimittel-Forschung 20100101 |
Harmine and imipramine promote antioxidant activities in prefrontal cortex and hippocampus. | Oxidative medicine and cellular longevity 20100101 |
A highly enantioselective access to tetrahydroisoquinoline and beta-carboline alkaloids with simple noyori-type catalysts in aqueous media. | Chemistry (Weinheim an der Bergstrasse, Germany) 20091207 |
Hollow fibre-supported liquid membrane extraction and LC-MS/MS detection for the analysis of heterocyclic amines in urine samples. | Molecular nutrition & food research 20091201 |
DH166, a beta-carboline derivative, inhibits the kinase activity of PLK1. | Cancer biology & therapy 20091201 |
Structure-activity relationship studies of manzamine A: amidation of positions 6 and 8 of the beta-carboline moiety. | Bioorganic & medicinal chemistry 20091115 |
Acute harmine administration induces antidepressive-like effects and increases BDNF levels in the rat hippocampus. | Progress in neuro-psychopharmacology & biological psychiatry 20091113 |
Synthesis and antiviral activity of beta-carboline derivatives bearing a substituted carbohydrazide at C-3 against poliovirus and herpes simplex virus (HSV-1). | European journal of medicinal chemistry 20091101 |
Harmine specifically inhibits protein kinase DYRK1A and interferes with neurite formation. | The FEBS journal 20091101 |
The Methyltetrahydro-{beta}-Carbolines in Maca (Lepidium meyenii). | Evidence-based complementary and alternative medicine : eCAM 20090901 |
Molecular determinants of beta-carboline inhibition of the glycine receptor. | Journal of neurochemistry 20090901 |
Tobacco mosaic virus (TMV) inhibitors from Picrasma quassioides Benn. | Journal of agricultural and food chemistry 20090812 |
Carboline alkaloids from Trigonostemon lii. | Planta medica 20090801 |
Photochemistry of norharmane in aqueous solution. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090801 |
Photophysics and rotational relaxation dynamics of a beta-carboline based fluorophore in cationic alkyltrimethylammonium bromide micelles. | Journal of colloid and interface science 20090715 |
Preparation and characterisation of fried chicken as a laboratory reference material for the analysis of heterocyclic amines. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090715 |
Synthesis of hybrid analogues of caffeine and eudistomin D and its affinity for adenosine receptors. | Bioorganic & medicinal chemistry 20090701 |
Harmol induces apoptosis by caspase-8 activation independently of Fas/Fas ligand interaction in human lung carcinoma H596 cells. | Anti-cancer drugs 20090601 |
Tabernines A-C, beta-carbolines from the leaves of Tabernaemontana elegans. | Journal of natural products 20090601 |
Advances in marine microbial symbionts in the china sea and related pharmaceutical metabolites. | Marine drugs 20090601 |
Marine antimalarials. | Marine drugs 20090601 |
Photophysics and rotational dynamics of a beta-carboline analogue in nonionic micelles: effect of variation of length of the headgroup and the tail of the surfactant. | The journal of physical chemistry. B 20090528 |
Biological activity of 1,2,3,4-tetrahydro-beta-carboline-3-carboxamides against Trypanosoma cruzi. | Acta tropica 20090401 |
5-Bromo-8-methoxy-1-methyl-beta-carboline, an alkaloid from the New Zealand marine bryozoan Pterocella vesiculosa. | Journal of natural products 20090401 |
Dual emission of temperature-induced betacarboline self-associated hydrogen bond aggregates. | Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20090301 |
Analysis of heterocyclic amines and beta-carbolines by liquid chromatography-mass spectrometry in cooked meats commonly consumed in Korea. | Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090301 |
Synthesis and in vitro cytotoxic evaluation of novel 3,4,5-trimethoxyphenyl substituted beta-carboline derivatives. | European journal of medicinal chemistry 20090201 |
The effect of temperature on the stability of compounds used as UV-MALDI-MS matrix: 2,5-dihydroxybenzoic acid, 2,4,6-trihydroxyacetophenone, alpha-cyano-4-hydroxycinnamic acid, 3,5-dimethoxy-4-hydroxycinnamic acid, nor-harmane and harmane. | Journal of mass spectrometry : JMS 20090201 |
Zamamidines A and B, new manzamine alkaloids from the sponge Amphimedon species. | Organic letters 20090101 |
Antiplatelet activity of beta-carboline alkaloids from Perganum harmala: a possible mechanism through inhibiting PLCgamma2 phosphorylation. | Vascular pharmacology 20090101 |
Gas chromatographic analysis of dimethyltryptamine and beta-carboline alkaloids in ayahuasca, an Amazonian psychoactive plant beverage. | Phytochemical analysis : PCA 20090101 |
Floral nectar composition of Peganum harmala L. | Natural product research 20090101 |
beta-carboline alkaloid-enriched extract from the amazonian rain forest tree pao pereira suppresses prostate cancer cells. | Journal of the Society for Integrative Oncology 20090101 |
Optimized HPLC method for analysis of polar and nonpolar heterocyclic amines in cooked meat products. | Journal of AOAC International 20090101 |
Analysis of an RNA adduct formed from aminophenylnorharman. | Nucleic acids symposium series (2004) 20090101 |
Synthesis of novel tadalafil analogues and their evaluation as phosphodiesterase inhibitors and anticancer agents. | Arzneimittel-Forschung 20090101 |
Pharmacological alterations of anxious behaviour in mice depending on both strain and the behavioural situation. | PloS one 20090101 |
Smoking induces long-lasting effects through a monoamine-oxidase epigenetic regulation. | PloS one 20090101 |
Acquired auditory-visual synesthesia: A window to early cross-modal sensory interactions. | Psychology research and behavior management 20090101 |
Synthesis and cytotoxic activities of 1-benzylidine substituted beta-carboline derivatives. | Bioorganic & medicinal chemistry letters 20081215 |
Parallel factor analysis of spider fluorophores. | Journal of photochemistry and photobiology. B, Biology 20081211 |
Mana-Hox displays anticancer activity against prostate cancer cells through tubulin depolymerization and DNA damage stress. | Naunyn-Schmiedeberg's archives of pharmacology 20081201 |
DYRK1A phosphorylates caspase 9 at an inhibitory site and is potently inhibited in human cells by harmine. | The FEBS journal 20081201 |
The role of prior stressor controllability and the dorsal raphé nucleus in sucrose preference and social exploration. | Behavioural brain research 20081103 |
3D and quantum QSAR of non-benzodiazepine compounds. | European journal of medicinal chemistry 20081101 |
Antifungal activity of the termite alkaloid norharmane against the mycelial growth of Metarhizium anisopliae and Aspergillus nomius. | Journal of invertebrate pathology 20081101 |
Effect of Peganum harmala or its beta-carboline alkaloids on certain antibiotic resistant strains of bacteria and protozoa from poultry. | Phytotherapy research : PTR 20081101 |
Oxidative metabolism of the bioactive and naturally occurring beta-carboline alkaloids, norharman and harman, by human cytochrome P450 enzymes. | Chemical research in toxicology 20081101 |
Metal-catalyzed reaction of N-(2-indolyl)methyl, N-bis(trimethylsilyl)methyl diazoamides: an entry into the beta-carboline ring system. | Chemical communications (Cambridge, England) 20081021 |
Identification of N,N-dimethyltryptamine and beta-carbolines in psychotropic ayahuasca beverage. | Biomedical chromatography : BMC 20081001 |
Furan oligomers and beta-carbolines from terrestrial streptomycetes. | Journal of natural products 20080901 |
A versatile cyclodehydration reaction for the synthesis of isoquinoline and beta-carboline derivatives. | Organic letters 20080821 |
A case of beta-carboline alkaloid intoxication following ingestion of Peganum harmala seed extract. | Forensic science international 20080806 |
Cytotoxicity of the beta-carboline alkaloids harmine and harmaline in human cell assays in vitro. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080801 |
Potent and selective antiplasmodial activity of the cyanobacterial alkaloid nostocarboline and its dimers. | Bioorganic & medicinal chemistry letters 20080801 |
The effects of rivastigmine plus selegiline on brain acetylcholinesterase, (Na, K)-, Mg-ATPase activities, antioxidant status, and learning performance of aged rats. | Neuropsychiatric disease and treatment 20080801 |
The use of natural product scaffolds as leads in the search for trypanothione reductase inhibitors. | Bioorganic & medicinal chemistry 20080715 |
Quantitative structure-activity relationship studies of a series of non-benzodiazepine structural ligands binding to benzodiazepine receptor. | European journal of medicinal chemistry 20080701 |
Photophysics of a beta-carboline based non-ionic probe in anionic and zwitterionic liposome membranes. | Chemistry and physics of lipids 20080701 |
Nonsymmetrical beta-carboline dimers from an Ascidian, Didemnum sp. | Journal of natural products 20080701 |
Quantification of heterocyclic aromatic amines in fried meat by HPTLC/UV-FLD and HPLC/UV-FLD: a comparison of two methods. | Journal of agricultural and food chemistry 20080625 |
Effects of harman and norharman on dopamine biosynthesis and L-DOPA-induced cytotoxicity in PC12 cells. | European journal of pharmacology 20080610 |
Indolealkylamines: biotransformations and potential drug-drug interactions. | The AAPS journal 20080601 |
Influence of the presence of methyl cyclodextrins in high-performance liquid chromatography mobile phases on the separation of beta-carboline alkaloids. | Journal of chromatography. A 20080530 |
Electronic structure of the ground and excited states of beta-carboline. | Chemphyschem : a European journal of chemical physics and physical chemistry 20080421 |
Synthesis of eudistomin D analogues and its effects on adenosine receptors. | Bioorganic & medicinal chemistry 20080401 |
Gamma-carboline derivatives with anti-bovine viral diarrhea virus (BVDV) activity. | Bioorganic & medicinal chemistry 20080401 |
Effect of surfactant chain length on the binding interaction of a biological photosensitizer with cationic micelles. | The journal of physical chemistry. B 20080327 |
Daytime Ayahuasca administration modulates REM and slow-wave sleep in healthy volunteers. | Psychopharmacology 20080201 |
The enantioselective total synthesis of a beta-carboline alkaloid, (S)-(-)-dichotomine C. | Chemical & pharmaceutical bulletin 20080201 |
Beta-carboline alkaloids from a Korean tunicate Eudistoma sp. | Journal of natural products 20080201 |
Strictosidine synthase: mechanism of a Pictet-Spengler catalyzing enzyme. | Journal of the American Chemical Society 20080116 |
A newly developed assay for the quantitative determination of antimicrobial (anticyanobacterial) activity of both hydrophilic and lipophilic test compounds without any restriction. | Microbiological research 20080101 |
Screening of microalgae for species excreting norharmane, a manifold biologically active indole alkaloid. | Microbiological research 20080101 |
Determination of beta-carboline alkaloids in fruiting bodies of Hygrophorus spp. by liquid chromatography/electrospray ionisation tandem mass spectrometry. | Phytochemical analysis : PCA 20080101 |
Effect of norharmane in vitro on juvenile hormone epoxide hydrolase activity in the lower termite, Reticulitermes speratus. | Journal of insect science (Online) 20080101 |
Degradation of heterocyclic aromatic amines in oil under storage and frying conditions and reduction of their mutagenic potential. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20071101 |
Identification and occurrence of beta-carboline alkaloids in raisins and inhibition of monoamine oxidase (MAO). | Journal of agricultural and food chemistry 20071017 |
Tumor-initiating potency of a novel heterocyclic amine, aminophenylnorharman in mouse colonic carcinogenesis model. | International journal of cancer 20071015 |
Direct experimental evidence for a heterogeneous reaction of ozone with bromide at the air-aqueous interface. | The journal of physical chemistry. A 20071004 |
Coupled hydrogen-bonding interactions between beta-carboline derivatives and acetic acid. | Magnetic resonance in chemistry : MRC 20071001 |
Synthesis of 3,8,9-trisubstituted-1,7,9-triaza-fluorene-6-carboxylic acid derivatives as a new class of insulin secretagogues. | Bioorganic & medicinal chemistry 20070901 |
Towards GAG glycomics: analysis of highly sulfated heparins by MALDI-TOF mass spectrometry. | Glycobiology 20070901 |
Brunneins A-C, beta-carboline alkaloids from Cortinarius brunneus. | Journal of natural products 20070901 |
Sustained inhibition of brotizolam induced anterograde amnesia by norharmane and retrograde amnesia by L-glutamic acid in mice. | Behavioural brain research 20070822 |
Validation of an ion-pair liquid chromatography-electrospray-tandem mass spectrometry method for the determination of heterocyclic aromatic amines in meat-based infant foods. | Food additives and contaminants 20070801 |
DH334, a beta-carboline anti-cancer drug, inhibits the CDK activity of budding yeast. | Cancer biology & therapy 20070801 |
Rapid identification of enzyme variants for reengineered alkaloid biosynthesis in periwinkle. | Chemistry & biology 20070801 |
Theoretical and UV spectral study of isomeric 1-(quinolinyl)-beta-carbolines conformations. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070701 |
Differential effects of dopamine melanin on norharman-induced toxicity in PC12 cells. | Journal of neural transmission (Vienna, Austria : 1996) 20070701 |
Antioxidant properties of beta-carboline alkaloids are related to their antimutagenic and antigenotoxic activities. | Mutagenesis 20070701 |
Effect of cyclodextrin nanocavity confinement on the photophysics of a beta-carboline analogue: a spectroscopic study. | The journal of physical chemistry. B 20070628 |
Neuroprotective effects of the beta-carboline abecarnil studied in cultured cortical neurons and organotypic retinal cultures. | Neuropharmacology 20070601 |
Golden opportunities in natural product synthesis: first total synthesis of (-)-isocyclocapitelline and (-)-isochrysotricine by gold-catalyzed allene cycloisomerization. | Organic & biomolecular chemistry 20070521 |
Synthesis of hybrid molecules of caffeine and eudistomin D and its effects on adenosine receptors. | Bioorganic & medicinal chemistry 20070501 |
N-methyltetrahydro-beta-carboline analogs of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) neurotoxin are oxidized to neurotoxic beta-carbolinium cations by heme peroxidases. | Biochemical and biophysical research communications 20070427 |
Surfactant chain-length-dependent modulation of the prototropic transformation of a biological photosensitizer: norharmane in anionic micelles. | Langmuir : the ACS journal of surfaces and colloids 20070424 |
Flazinamide, a novel beta-carboline compound with anti-HIV actions. | Biochemical and biophysical research communications 20070420 |
From pyrroles to 1-oxo-2,3,4,9-tetrahydro-1H-beta-carbolines: a new class of orally bioavailable mGluR1 antagonists. | Bioorganic & medicinal chemistry letters 20070415 |
Heterocyclic amines in griddled beef steak analysed using a single extract clean-up procedure. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20070401 |
Solid-phase fluorescence and ionization efficiency in negative-ion matrix-assisted laser desorption/ionization of neutral oligosaccharides: interaction between beta-carboline matrix and ammonium salt. | Journal of the American Society for Mass Spectrometry 20070401 |
Factors influencing the norharman and harman contents in espresso coffee. | Journal of agricultural and food chemistry 20070307 |
Determination of beta-carboline alkaloids in foods and beverages by high-performance liquid chromatography with electrochemical detection at a glassy carbon electrode modified with carbon nanotubes. | Analytica chimica acta 20070307 |
Anticonvulsants in sports: ethical considerations. | Epilepsy & behavior : E&B 20070301 |
Binding interaction of a biological photosensitizer with serum albumins: a biophysical study. | Biomacromolecules 20070301 |
Methylglyoxal-derived beta-carbolines formed from tryptophan and its derivates in the Maillard reaction. | Amino acids 20070201 |
Validation of a new planar chromatographic method for quantification of the heterocyclic aromatic amines most frequently found in meat. | Analytical and bioanalytical chemistry 20070201 |
Synthesis and evaluation of antitumor activity of novel N-acyllavendamycin analogues and quinoline-5,8-diones. | Bioorganic & medicinal chemistry 20070101 |
Risk assessment of ritual use of oral dimethyltryptamine (DMT) and harmala alkaloids. | Addiction (Abingdon, England) 20070101 |
Detection of aminophenylnorharman, a possible endogenous mutagenic and carcinogenic compound, in human urine samples. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070101 |
beta-Carboline alkaloids: biochemical and pharmacological functions. | Current medicinal chemistry 20070101 |
From the behavioral pharmacology of beta-carbolines to seizures, anxiety, and memory. | TheScientificWorldJournal 20070101 |
Identification of the endogenous key substrates of the human organic cation transporter OCT2 and their implication in function of dopaminergic neurons. | PloS one 20070101 |
Plants used traditionally to treat malaria in Brazil: the archives of Flora Medicinal. | Journal of ethnobiology and ethnomedicine 20070101 |
Mapping of oxidative stress responses of human tumor cells following photodynamic therapy using hexaminolevulinate. | BMC genomics 20070101 |
Pharmacology of the beta-carboline FG-7,142, a partial inverse agonist at the benzodiazepine allosteric site of the GABA A receptor: neurochemical, neurophysiological, and behavioral effects. | CNS drug reviews 20070101 |
Synthesis, crystal structure and biological activity of beta-carboline based selective CDK4-cyclin D1 inhibitors. | Organic & biomolecular chemistry 20061221 |
Efficient and sensitive method for quantitative analysis of alkaloids in hardinggrass (Phalaris aquatica L.). | Journal of agricultural and food chemistry 20061213 |
Monoamine oxidase A rather than monoamine oxidase B inhibition increases nicotine reinforcement in rats. | The European journal of neuroscience 20061201 |
Receptor-based pharmacophores for serotonin 5-HT7R antagonists-implications to selectivity. | Journal of medicinal chemistry 20061116 |
6-Hydroxy- and 6-methoxy-beta-carbolines as acetyl- and butyrylcholinesterase inhibitors. | Bioorganic & medicinal chemistry letters 20061115 |
Anti-prostate cancer activity of a beta-carboline alkaloid enriched extract from Rauwolfia vomitoria. | International journal of oncology 20061101 |
Activation of aminophenylnorharman, aminomethylphenylnorharman and aminophenylharman to genotoxic metabolites by human N-acetyltransferases and cytochrome P450 enzymes expressed in Salmonella typhimurium umu tester strains. | Mutagenesis 20061101 |
Effects of beta-carboline alkaloids on the object recognition task in mice. | Life sciences 20061026 |
Effect of red wine marinades on the formation of heterocyclic amines in fried chicken breast. | Journal of agricultural and food chemistry 20061018 |
Synthesis and cytotoxic activities of beta-carboline amino acid ester conjugates. | Bioorganic & medicinal chemistry 20061015 |
Design of beta-carboline derivatives as DNA-targeting antitumor agents. | European journal of medicinal chemistry 20061001 |
Parkinson's disease-like syndrome in rats induced by 2,9-dimethyl-beta-carbolinium ion, a beta-carboline occurring in the human brain. | Behavioural pharmacology 20060901 |
Inhibition of neuronal nitric oxide synthase activity by N1-acetyl-5-methoxykynuramine, a brain metabolite of melatonin. | Journal of neurochemistry 20060901 |
Partial least squares-based multivariate spectral calibration method for simultaneous determination of beta-carboline derivatives in Peganum harmala seed extracts. | Analytica chimica acta 20060811 |
Monoamine oxidase inhibitors allow locomotor and rewarding responses to nicotine. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20060801 |
Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic culture. | Journal of neurochemistry 20060801 |
Effect of nanocavity confinement on the rotational relaxation dynamics: 3-acetyl-4-oxo-6,7-dihydro-12H indolo-[2,3-a] quinolizine in micelles. | The Journal of chemical physics 20060728 |
Analysis of monoamine oxidase enzymatic activity by reversed-phase high performance liquid chromatography and inhibition by beta-carboline alkaloids occurring in foods and plants. | Journal of chromatography. A 20060707 |
Antidepressant-like effect of harmane and other beta-carbolines in the mouse forced swim test. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20060701 |
Phytochemical and pharmacological study of roots and leaves of Guiera senegalensis J.F. Gmel (Combretaceae). | Journal of ethnopharmacology 20060630 |
Antimalarial activity of a new family of analogues of manzamine A. | Organic letters 20060608 |
A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells. | The Journal of pharmacology and experimental therapeutics 20060601 |
Identification of norharman as the cytotoxic compound produced by the sponge (Hymeniacidon perleve)-associated marine bacterium Pseudoalteromonas piscicida and its apoptotic effect on cancer cells. | Biotechnology and applied biochemistry 20060601 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Beta-carboline derivatives: novel photosensitizers that intercalate into DNA to cause direct DNA damage in photodynamic therapy. | Biochemical and biophysical research communications 20060414 |
Norharman-induced motoric impairment in mice: neurodegeneration and glial activation in substantia nigra. | Journal of neural transmission (Vienna, Austria : 1996) 20060301 |
In vitro and ex vivo distribution of [3H]harmane, an endogenous beta-carboline, in rat brain. | Neuropharmacology 20060301 |
Preparation, structure and spasmolytic activities of some derivatives of harmine series of alkaloids. | Natural product research 20060301 |
The alkaloid alstonine: a review of its pharmacological properties. | Evidence-based complementary and alternative medicine : eCAM 20060301 |
Effect of chlorine as substituent on the photochemistry and acid-base properties of beta-carboline alkaloids. | Journal of photochemistry and photobiology. B, Biology 20060201 |
Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee. | Life sciences 20060118 |
Syntheses of new substituted triazino tetrahydroisoquinolines and beta-carbolines as novel antileishmanial agents. | European journal of medicinal chemistry 20060101 |
Antialgal, antibacterial and antifungal activity of two metabolites produced and excreted by cyanobacteria during growth. | Microbiological research 20060101 |
2,9-Dimethyl-beta-carbolinium, a neurotoxin occurring in human brain, is a potent inducer of apoptosis as 1-methyl-4-phenylpyridinium. | Neuroscience 20060101 |
Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice. | Cell division 20060101 |
Toxicity and metabolism of the chloral-derived mammalian alkaloid 1-trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) in PC12 cells. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20060101 |
DNA binding properties of 9-substituted harmine derivatives. | Biochemical and biophysical research communications 20051223 |
beta-Carboline alkaloid suppresses NF-kappaB transcriptional activity through inhibition of IKK signaling pathway. | Journal of toxicology and environmental health. Part A 20051210 |
Isolation and chemical characterization of PwTx-II: a novel alkaloid toxin from the venom of the spider Parawixia bistriata (Araneidae, Araneae). | Toxicon : official journal of the International Society on Toxinology 20051201 |
The beta-carboline analog Mana-Hox causes mitotic aberration by interacting with DNA. | Chemistry & biology 20051201 |
Nostocarboline: isolation and synthesis of a new cholinesterase inhibitor from Nostoc 78-12A. | Journal of natural products 20051201 |
Conformationally constrained N1-arylsulfonyltryptamine derivatives as 5-HT6 receptor antagonists. | Bioorganic & medicinal chemistry letters 20051101 |
Harmane inhibits serotonergic dorsal raphe neurons in the rat. | Psychopharmacology 20051101 |
Isolation of mutagenic beta-carboline derivatives after nitrite treatment of maillard reaction mixtures and analysis of these compounds from foodstuffs and human urine. | Bioscience, biotechnology, and biochemistry 20051101 |
Investigation of the separation of heterocyclic aromatic amines by reversed phase ion-pair liquid chromatography coupled with tandem mass spectrometry: the role of ion pair reagents on LC-MS/MS sensitivity. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051025 |
Design, synthesis and in vitro and in vivo antitumor activities of novel beta-carboline derivatives. | European journal of medicinal chemistry 20051001 |
Isolation and characterization of norharmane from Reticulitermes termites (Isoptera: Rhinotermitidae). | Journal of economic entomology 20051001 |
Effects of harmaline on anxiety-related behavior in mice. | Physiology & behavior 20050915 |
Design, synthesis and bioactivities of TAR RNA targeting beta-carboline derivatives based on Tat-TAR interaction. | European journal of medicinal chemistry 20050901 |
High-affinity binding of beta-carbolines to imidazoline I2B receptors and MAO-A in rat tissues: norharman blocks the effect of morphine withdrawal on DOPA/noradrenaline synthesis in the brain. | European journal of pharmacology 20050822 |
Tangutorine induces p21 expression and abnormal mitosis in human colon cancer HT-29 cells. | Biochemical pharmacology 20050715 |
Photochemistry of the alkaloids eudistomin N (6-bromo-nor-harmane) and eudistomin O (8-bromo-nor-harmane) and other bromo-beta-carbolines. | Journal of photochemistry and photobiology. B, Biology 20050701 |
Gesashidine A, a beta-carboline alkaloid with an imidazole ring from a Thorectidae sponge. | Journal of natural products 20050701 |
Toxocara canis: search for a potential drug amongst beta-carboline alkaloids--in vitro and mouse studies. | Experimental parasitology 20050601 |
Synthesis and evaluation of beta-carbolinium cations as new antimalarial agents based on pi-delocalized lipophilic cation (DLC) hypothesis. | Chemical & pharmaceutical bulletin 20050601 |
Alkaloids and aromatics of Cyathobasis fruticulosa (Bunge) Aellen. | Journal of natural products 20050601 |
Developmental regulation of beta-carboline-induced inhibition of glycine-evoked responses depends on glycine receptor beta subunit expression. | Molecular pharmacology 20050501 |
Characterization of some synthetic Ru and Ir complexes by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | Journal of mass spectrometry : JMS 20050501 |
Comparison of the Protective Effect of Indole beta-carbolines and R-(-)-deprenyl Against Nitrogen Species-Induced Cell Death in Experimental Culture Model of Parkinson's Disease. | Journal of clinical neurology (Seoul, Korea) 20050401 |
In-source and postsource decay in negative-ion matrix-assisted laser desorption/ionization time-of-flight mass spectrometry of neutral oligosaccharides. | Analytical chemistry 20050315 |
Encapsulation of norharmane in cyclodextrin: formation of 1:1 and 1:2 inclusion complexes. | Journal of photochemistry and photobiology. B, Biology 20050301 |
Synthesis and in vitro cytotoxic evaluation of 1,3-bisubstituted and 1,3,9-trisubstituted beta-carboline derivatives. | European journal of medicinal chemistry 20050301 |
Agonistic effects of the beta-carboline DMCM revealed in GABA(A) receptor gamma 2 subunit F77I point-mutated mice. | Neuropharmacology 20050301 |
Lack of combination hepatocarcinogenicity of harman, norharman and amitrole when given with NaNO2 in the rat. | The Journal of toxicological sciences 20050201 |
Human monoamine oxidase is inhibited by tobacco smoke: beta-carboline alkaloids act as potent and reversible inhibitors. | Biochemical and biophysical research communications 20050114 |
Photophysics in motionally constrained bioenvironment: interaction of norharmane with bovine serum albumin. | Photochemistry and photobiology 20050101 |
Beta-carbolines induce apoptosis in cultured cerebellar granule neurons via the mitochondrial pathway. | Neuropharmacology 20050101 |
Red maca (Lepidium meyenii) reduced prostate size in rats. | Reproductive biology and endocrinology : RB&E 20050101 |
Permissive nicotine regulation as a complement to traditional tobacco control. | BMC public health 20050101 |
Differential modulation of microglia superoxide anion and thromboxane B2 generation by the marine manzamines. | BMC pharmacology 20050101 |
Fluorescence quenching of beta-carboline alkaloids in micellar media. A study to select the adequate surfactant to use in analytical techniques. | Luminescence : the journal of biological and chemical luminescence 20050101 |
Beta-carboline and quinoline alkaloids in root cultures and intact plants of Peganum harmala. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20050101 |
Comprehensive photochemistry and photophysics of land- and marine-based beta-carbolines employing time-resolved emission and flash transient spectroscopy. | Photochemistry and photobiology 20050101 |
Addition of various carbohydrates to beef burgers affects the formation of heterocyclic amines during frying. | Journal of agricultural and food chemistry 20041215 |
New beta-carboline alkaloids from the Andaman Sea sponge Dragmacidon sp. | Journal of natural products 20041201 |
Relative exposure to beta-carbolines norharman and harman from foods and tobacco smoke. | Food additives and contaminants 20041101 |
The putative imidazoline receptor agonist, harmane, promotes intracellular calcium mobilisation in pancreatic beta-cells. | European journal of pharmacology 20041006 |
Carcinogenicity of aminophenylnorharman, a possible novel endogenous mutagen, formed from norharman and aniline, in F344 rats. | Carcinogenesis 20041001 |
Norharman and alcohol-dependency in male Wistar rats. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20041001 |
Synthesis, acute toxicities, and antitumor effects of novel 9-substituted beta-carboline derivatives. | Bioorganic & medicinal chemistry 20040901 |
Analysis of alpha- and beta-carbolines in mainstream smoke of reference cigarettes by gas chromatography-mass spectrometry. | Journal of chromatography. A 20040813 |
Identification of cytochrome P-450s involved in the formation of APNH from norharman with aniline. | Mutation research 20040808 |
Antibiotic-mediated release of tumour necrosis factor alpha and norharman in patients with hospital-acquired pneumonia and septic encephalopathy. | Intensive care medicine 20040801 |
Synthesis and antimycobacterial activity of some beta-carboline alkaloids. | Natural product research 20040801 |
A comparative molecular field analysis of cytotoxic beta-carboline analogs. | Acta pharmacologica Sinica 20040701 |
A fast assembly of pentacyclic benz[f]indolo[2,3-a]quinolizidine core by tandem intermolecular formal aza-[3 + 3] cycloaddition/Pictet-Spengler cyclization: a formal synthesis of (+/-)-tangutorine. | The Journal of organic chemistry 20040625 |
Synthesis and biological evaluation of novel beta-carboline derivatives as Tat-TAR interaction inhibitors. | Bioorganic & medicinal chemistry letters 20040621 |
Characterization of the cytotoxic mechanism of Mana-Hox, an analog of manzamine alkaloids. | Biochimica et biophysica acta 20040611 |
Cytotoxic alkaloids from the marine sponge Thorectandra sp. | Natural product research 20040601 |
Dopamine transporter-mediated cytotoxicity of beta-carbolinium derivatives related to Parkinson's disease: relationship to transporter-dependent uptake. | Journal of neurochemistry 20040501 |
Photophysics of norharmane in micellar environments: a fluorometric study. | Biophysical chemistry 20040501 |
Clinical investigations of the therapeutic potential of ayahuasca: rationale and regulatory challenges. | Pharmacology & therapeutics 20040501 |
Pi-delocalized beta-carbolinium cations as potential antimalarials. | Bioorganic & medicinal chemistry letters 20040405 |
[Synthesis of 1-indole substituted beta-carboline alkaloid and its derivatives and evaluation of their preliminary antitumor activities]. | Yao xue xue bao = Acta pharmaceutica Sinica 20040401 |
High-performance liquid chromatographic analysis of beta-carbolines in human scalp hair. | Journal of chromatography. A 20040326 |
Occurrence of heterocyclic amines in several home-cooked meat dishes of the Spanish diet. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325 |
Exposure to beta-carbolines norharman and harman. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325 |
Mutagens formed from beta-carbolines with aromatic amines. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040325 |
Regulation and biochemistry of mouse molybdo-flavoenzymes. The DBA/2 mouse is selectively deficient in the expression of aldehyde oxidase homologues 1 and 2 and represents a unique source for the purification and characterization of aldehyde oxidase. | The Journal of biological chemistry 20040305 |
Long-term retention of neurotoxic beta-carbolines in brain neuromelanin. | Journal of neural transmission (Vienna, Austria : 1996) 20040201 |
The effects of imidazoline agents on the aggregation of human platelets. | The Journal of pharmacy and pharmacology 20040201 |
In vitro activity of the beta-carboline alkaloids harmane, harmine, and harmaline toward parasites of the species Leishmania infantum. | Experimental parasitology 20040101 |
Characterization of humic substances by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. | Rapid communications in mass spectrometry : RCM 20040101 |
A new efficient synthetic methodology for tetrahydroisoquinoline and tetrahydro-beta-carboline derivatives using the Pictet-Spengler reaction. | Molecular diversity 20040101 |
Effect of diazepam on the CNS excitation and behavioural changes induced by harmaline and its newly synthesized analogues. | Pakistan journal of pharmaceutical sciences 20040101 |
Effects of the beta-carbolines, harmane and pinoline, on insulin secretion from isolated human islets of Langerhans. | European journal of pharmacology 20031215 |
Potent genotoxicity of aminophenylnorharman, formed from non-mutagenic norharman and aniline, in the liver of gpt delta transgenic mouse. | Carcinogenesis 20031201 |
Craving for cigarettes among low and high dependent smokers: impact of norharman. | Addiction biology 20031201 |
Comparative effects of efaroxan and beta-carbolines on the secretory activity of rodent and human beta cells. | Annals of the New York Academy of Sciences 20031201 |
Effect of harmane on mononeuropathic pain in rats. | Annals of the New York Academy of Sciences 20031201 |
Possibility of the involvement of 9H-pyrido[3,4-b]indole (norharman) in carcinogenesis via inhibition of cytochrome P450-related activities and intercalation to DNA. | Mutation research 20031110 |
Influence of antioxidants in virgin olive oil on the formation of heterocyclic amines in fried beefburgers. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20031101 |
Identification of tryptophan and beta-carboline as paralysins in larvae of the yellow mealworm, Tenebrio molitor. | Biochemical and biophysical research communications 20031010 |
Cytotoxic and antimalarial beta-carboline alkaloids from the roots of Eurycoma longifolia. | Journal of natural products 20031001 |
Detection and characterization of cyclodextrin complexes with beta-carboline derivatives by spectroscopic techniques. | Journal of pharmaceutical and biomedical analysis 20030808 |
Novel IKK inhibitors: beta-carbolines. | Bioorganic & medicinal chemistry letters 20030721 |
Photophysical properties of methyl beta-carboline-3-carboxylate mediated by hydrogen-bonded complexes--a comparative study in different solvents. | Biophysical chemistry 20030701 |
Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase. | Pharmacogenetics 20030601 |
New manzamine alkaloids with activity against infectious and tropical parasitic diseases from an Indonesian sponge. | Journal of natural products 20030601 |
Spectrofluorimetric determination of manzamine A in spiked human urine and plasma. | Die Pharmazie 20030601 |
Chemical constituents of Taraxacum formosanum. | Chemical & pharmaceutical bulletin 20030501 |
Design, synthesis, and biological evaluation of non-peptidic ligands at the Xenopus laevis skin-melanocortin receptor. | European journal of medicinal chemistry 20030501 |
Design, synthesis and biological activity of beta-carboline-based type-5 phosphodiesterase inhibitors. | Bioorganic & medicinal chemistry letters 20030417 |
Contribution of individual cytochrome P450 isozymes to the O-demethylation of the psychotropic beta-carboline alkaloids harmaline and harmine. | The Journal of pharmacology and experimental therapeutics 20030401 |
Shishijimicins A-C, novel enediyne antitumor antibiotics from the ascidian Didemnum proliferum(1). | Journal of the American Chemical Society 20030226 |
Isolation and identification of two [(3)H]norharman- ([(3)H]beta-carboline)-binding proteins from rat liver. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030125 |
Mechanism-based pharmacokinetic/pharmacodynamic modeling of the electroencephalogram effects of GABAA receptor modulators: in vitro-in vivo correlations. | The Journal of pharmacology and experimental therapeutics 20030101 |
Beta-carboline alkaloids from a New Zealand marine bryozoan, Cribricellina cribraria. | Natural product research 20030101 |
Tetrahydroisoquinoline and beta-carboline alkaloids from Haloxylon articulatum (Cav.) Bunge (Chenopodiaceae). | Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101 |
The role of GABA in the pathophysiology and treatment of anxiety disorders. | Psychopharmacology bulletin 20030101 |
Synthesis of beta- and gamma-carbolines by the palladium-catalyzed iminoannulation of alkynes. | The Journal of organic chemistry 20021227 |
Elevation of blood beta-carboline alkaloids in essential tremor. | Neurology 20021224 |
Rhythmicity without synchrony in the electrically uncoupled inferior olive. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20021215 |
Effects of ayahuasca on sensory and sensorimotor gating in humans as measured by P50 suppression and prepulse inhibition of the startle reflex, respectively. | Psychopharmacology 20021201 |
Determination of N,N-dimethyltryptamine and beta-carboline alkaloids in human plasma following oral administration of Ayahuasca. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20021105 |
Structure of DNA adduct formed with aminophenylnorharman, being responsible for the comutagenic action of norharman with aniline. | Chemical research in toxicology 20021001 |
In vitro and in vivo formation of aminophenylnorharman from norharman and aniline. | Mutation research 20020930 |
Synthesis and cytotoxic activity of pyridazino[1',6':1,2]pyrido[3,4-b]indol-5-inium derivatives as anti-cancer agents. | Bioorganic & medicinal chemistry letters 20020916 |
Contribution of the alpha1-GABA(A) receptor subtype to the pharmacological actions of benzodiazepine site inverse agonists. | Neuropharmacology 20020901 |
High-performance liquid chromatographic, capillary electrophoretic and capillary electrophoretic-electrospray ionisation mass spectrometric analysis of selected alkaloid groups. | Journal of chromatography. A 20020816 |
Screening for heterocyclic amines in chicken cooked in various ways. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020801 |
The biosynthesis of beta-carboline and quinolizidine alkaloids of Alangium lamarckii. | Phytochemistry 20020801 |
5-hydroxytryptamine-derived alkaloids from two marine sponges of the genus Hyrtios. | Journal of natural products 20020801 |
Multistep mass spectrometry of heterocyclic amines in a quadrupole ion trap mass analyser. | Journal of mass spectrometry : JMS 20020801 |
Identification and occurrence of the bioactive beta-carbolines norharman and harman in coffee brews. | Food additives and contaminants 20020801 |
Tetrahydro-beta-carboline alkaloids that occur in foods and biological systems act as radical scavengers and antioxidants in the ABTS assay. | Free radical research 20020801 |
Identification and occurrence of the novel alkaloid pentahydroxypentyl-tetrahydro-beta-carboline-3-carboxylic acid as a tryptophan glycoconjugate in fruit juices and jams. | Journal of agricultural and food chemistry 20020731 |
1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) and related derivatives: chemistry and biochemical effects on catecholamine biosynthesis. | Bioorganic & medicinal chemistry 20020701 |
The anti-epileptic drug levetiracetam reverses the inhibition by negative allosteric modulators of neuronal GABA- and glycine-gated currents. | British journal of pharmacology 20020701 |
Thermodynamic study of small hydrophobic ions at the water-lipid interface. | Journal of colloid and interface science 20020701 |
Phenylethanolamine N-methyltransferase has beta-carboline 2N-methyltransferase activity: hypothetical relevance to Parkinson's disease. | Neurochemistry international 20020601 |
Topographic pharmaco-EEG mapping of the effects of the South American psychoactive beverage ayahuasca in healthy volunteers. | British journal of clinical pharmacology 20020601 |
Natural variations of precursors in pig meat affect the yield of heterocyclic amines--effects of RN genotype, feeding regime, and sex. | Journal of agricultural and food chemistry 20020508 |
The levels of norharman are high enough after smoking to affect monoamineoxidase B in platelets. | European journal of pharmacology 20020419 |
Beta-carbolines as specific inhibitors of cyclin-dependent kinases. | Bioorganic & medicinal chemistry letters 20020408 |
[The effect on other individual presentations of the goldfish by FG7142 injection]. | Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20020401 |
Induction of sister chromatid exchanges and chromosome aberrations in cultured mammalian cells treated with aminophenylnorharman formed by norharman with aniline. | Mutation research 20020325 |
Genotoxic and recombinogenic activities of the two beta-carboline alkaloids harman and harmine in Saccharomyces cerevisiae. | Mutation research 20020320 |
Characterization of the discriminable stimulus produced by 2-BFI: effects of imidazoline I(2)-site ligands, MAOIs, beta-carbolines, agmatine and ibogaine. | British journal of pharmacology 20020301 |
Maternal and developmental toxicity in mice by aminophenylnorharman, formed from norharman and aniline. | Human & experimental toxicology 20020301 |
Beta-carboline-carbohydrate hybrids: molecular design, chemical synthesis and evaluation of novel DNA photocleavers. | Bioorganic & medicinal chemistry letters 20020225 |
The impact of smoking and drinking on plasma levels of norharman. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020201 |
Synergistic in vitro antimalarial activity of plant extracts used as traditional herbal remedies in Mali. | Parasitology research 20020201 |
Indole and beta-carboline alkaloids from Geissospermum sericeum. | Journal of natural products 20020101 |
An in vitro evaluation of human DNA topoisomerase I inhibition by Peganum harmala L. seeds extract and its beta-carboline alkaloids. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20020101 |
Interaction of folk medicinal plant extracts with human alpha2-adrenoceptor subtypes. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20020101 |
An in vitro study on the kinetics, subcellular distribution and phototoxicity of harmine in human tumor cells. | Bollettino chimico farmaceutico 20020101 |
Potential neurotoxic 'agents provocateurs' in Parkinson's disease. | Neurotoxicology and teratology 20020101 |
[Serum norharman and harman analysis using high pressure liquid chromatography/mass spectrometry and value of beta-carbolines as blood alcohol markers]. | Archiv fur Kriminologie 20020101 |
Total syntheses of beta-carboline alkaloids, (R)-(-)-pyridindolol K1, (R)-(-)-pyridindolol K2, and (R)-(-)-pyridindolol. | The Journal of organic chemistry 20011228 |
Toxicokinetics of tremorogenic natural products, harmane and harmine, in male Sprague-Dawley rats. | Journal of toxicology and environmental health. Part A 20011221 |
Degradation of tetrahydro-beta-carbolines in the presence of nitrite: HPLC-MS analysis of the reaction products. | Journal of agricultural and food chemistry 20011201 |
Genotoxic effects of the alkaloids harman and harmine assessed by comet assay and chromosome aberration test in mammalian cells in vitro. | Pharmacology & toxicology 20011201 |
New cytotoxic N-methylated beta-carboline alkaloids from the marine ascidian Eudistoma gilboverde. | Journal of natural products 20011101 |
beta-carboline binding to imidazoline receptors. | Drug and alcohol dependence 20011001 |
Pharmacokinetics of the beta-carboline norharman in man. | Life sciences 20010921 |
Testicular toxicity in F344 rats by aminophenylnorharman, formed from norharman and aniline. | Toxicology and applied pharmacology 20010901 |
Stimulatory effect of harmane and other beta-carbolines on locus coeruleus neurons in anaesthetized rats. | Neuroscience letters 20010810 |
Why are the terpenoid indole alkaloids of type I homochiral? | Chirality 20010801 |
Oxidative DNA damage by an N-hydroxy metabolite of the mutagenic compound formed from norharman and aniline. | Mutation research 20010725 |
Anti-AIDS agents. 46. Anti-HIV activity of harman, an anti-HIV principle from Symplocos setchuensis, and its derivatives. | Journal of natural products 20010701 |
[Synthetic studies of the bioactive natural products by using the thermal electrocyclic reaction of 6 pi electron systems]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20010701 |
Structures of mutagens produced by the co-mutagen norharman with o- and m-toluidine isomers. | Mutation research 20010627 |
The acute effects of norharman on cocaine self-administration and sensorimotor function in male Wistar rats. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20010601 |
Psychotogenic properties of benzodiazepine receptor inverse agonists. | Psychopharmacology 20010601 |
Tryptophan: a precursor for the endogenous synthesis of norharman in man. | Neuroscience letters 20010511 |
Reaction of tryptophan with carbohydrates: identification and quantitative determination of novel beta-carboline alkaloids in food. | Journal of agricultural and food chemistry 20010501 |
L-Deprenyl prevents the cell hypoxia induced by dopaminergic neurotoxins, MPP(+) and beta-carbolinium: a microdialysis study in rats. | Neuroscience letters 20010420 |
Exposure of a 'witness rat' to one treated with beta-carboline FG 7142 does not increase dopamine turnover in the medial prefrontal cortex of the 'witness rat'. | Neuroscience letters 20010420 |
Hydrogen bonding NH/pi interactions between betacarboline and methyl benzene derivatives. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20010401 |
Induction of liver preneoplastic lesions by aminophenylnorharman, formed from norharman and aniline, in male F344 rats. | Cancer letters 20010226 |
Synthesis and biological evaluation of DNA targeting flexible side-chain substituted beta-carboline derivatives. | Bioorganic & medicinal chemistry letters 20010226 |
Canthin-6-one and beta-carboline alkaloids from Eurycoma harmandiana. | Phytochemistry 20010201 |
Cis- and trans-platinum and palladium complexes: a comparative study review as antitumour agents. | Bollettino chimico farmaceutico 20010101 |
Norharman, an indoleamine-derived beta-carboline, but not Trp-P-2, a gamma-carboline, induces apoptotic cell death in human neuroblastoma SH-SY5Y cells. | Journal of neural transmission (Vienna, Austria : 1996) 20010101 |
Effects of beta- and gamma-carboline derivatives of DNA topoisomerase activities. | Mutation research 19960201 |
ELISA of pentosidine, an advanced glycation end product, in biological specimens. | Clinical chemistry 19940901 |
Inhibition of indoleamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase by beta-carboline and indole derivatives. | Archives of biochemistry and biophysics 19840801 |