Aminoquinolines as fluorescent labels for hydrophilic interaction liquid chromatography of oligosaccharides.

Biological chemistry 20120801

Enantioselective synthesis of AG-041R by using N-heteroarenesulfonyl cinchona alkaloid amides as organocatalysts.

Chemistry (Weinheim an der Bergstrasse, Germany) 20120723

Optical turn-on sensor based on graphene oxide for selective detection of D-glucosamine.

Analytical chemistry 20120703

Elimination therapy for the endemic malarias.

Current infectious disease reports 20120601

Amino acid, dipeptide and pseudodipeptide conjugates of ring-substituted 8-aminoquinolines: synthesis and evaluation of anti-infective, β-haematin inhibition and cytotoxic activities.

European journal of medicinal chemistry 20120601

Leishmaniasis: current status of available drugs and new potential drug targets.

Asian Pacific journal of tropical medicine 20120601

(8-Amino-quinoline-κ(2)N,N')bis-(1,1,1,5,5,5-hexa-fluoro-pentane-2,4-dionato-κ(2)O,O')cobalt(II).

Acta crystallographica. Section E, Structure reports online 20120401

Understanding the mechanisms for metabolism-linked hemolytic toxicity of primaquine against glucose 6-phosphate dehydrogenase deficient human erythrocytes: evaluation of eryptotic pathway.

Toxicology 20120329

A new practical approach towards the synthesis of unsymmetric and symmetric 1,10-phenanthroline derivatives at room temperature.

Chemical communications (Cambridge, England) 20120318

A quinoline based bis-urea receptor for anions: a selective receptor for hydrogen sulfate.

Natural product communications 20120301

Reactions of substituted pyridines with electrophilic boranes.

Dalton transactions (Cambridge, England : 2003) 20120221

Inhibition of human monoamine oxidase A and B by 5-phenoxy 8-aminoquinoline analogs.

Bioorganic & medicinal chemistry letters 20120215

Trichlorido{2-dimeth-oxy-methyl-4-methyl-6-[(quinolin-8-yl)imino-meth-yl]phenolato-κN,N',O}tin(IV).

Acta crystallographica. Section E, Structure reports online 20120201

Development of a borondipyrromethene-based Zn2+ fluorescent probe: solvent effects on modulation sensing ability.

Dalton transactions (Cambridge, England : 2003) 20120121

Palladium-catalyzed direct ortho-alkynylation of aromatic carboxylic acid derivatives.

Organic letters 20120106

Cytotoxic palladium(II) complexes of 8-aminoquinoline derivatives and the interaction with human serum albumin.

Journal of inorganic biochemistry 20120101

catena-Poly[[(8-amino-quinoline-κN,N')cadmium]-di-μ-thio-cyanato-κN:S;κS:N-[(8-amino-quinoline-κN,N')cadmium]-di-μ-chlorido].

Acta crystallographica. Section E, Structure reports online 20120101

3,3'-Bis(quinolin-8-yl)-1,1'-[4,4'-methyl-enebis(4,1-phenyl-ene)]diurea.

Acta crystallographica. Section E, Structure reports online 20120101

Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence 'transmission blocking' assay.

PloS one 20120101

Failure of Supervised Chloroquine and Primaquine Regimen for the Treatment of Plasmodium vivax in the Peruvian Amazon.

Malaria research and treatment 20120101

CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine.

Malaria journal 20120101

Copper chelator induced efficient episodic memory recovery in a non-transgenic Alzheimer's mouse model.

PloS one 20120101

Review: Improving the therapeutic index of 8-aminoquinolines by the use of drug combinations: review of the literature and proposal for future investigations.

The American journal of tropical medicine and hygiene 20111201

Dried matrix spot direct analysis: evaluating the robustness of a direct elution technique for use in quantitative bioanalysis.

Bioanalysis 20111201

2,4-Dibromo-6-[(quinolin-8-yl-amino)-methyl-idene]cyclo-hexa-2,4-dien-1-one monohydrate.

Acta crystallographica. Section E, Structure reports online 20111201

Method of applying internal standard to dried matrix spot samples for use in quantitative bioanalysis.

Analytical chemistry 20111115

OFF-ON-OFF fluorescence switch with T-latch function.

Organic letters 20111021

DFT study on the radical anions formed by primaquine and its derivatives.

Chemical research in toxicology 20110919

A near-infrared fluorescence turn-on sensor for sulfide anions.

Organic letters 20110902

A new rhodamine based colorimetric 'off-on' fluorescence sensor selective for Pd2+ along with the first bound X-ray crystal structure.

Chemical communications (Cambridge, England) 20110828

N-(Quinolin-8-yl)ferrocene-1-carbox-amide.

Acta crystallographica. Section E, Structure reports online 20110801

Pharmacokinetics of oral sitamaquine taken with or without food and safety and efficacy for treatment of visceral leishmaniais: a randomized study in Bihar, India.

The American journal of tropical medicine and hygiene 20110601

Why is Plasmodium vivax a neglected tropical disease?

PLoS neglected tropical diseases 20110601

8-aminoquinoline functionalized silica nanoparticles: a fluorescent nanosensor for detection of divalent zinc in aqueous and in yeast cell suspension.

ACS applied materials & interfaces 20110501

Sitamaquine as a putative antileishmanial drug candidate: from the mechanism of action to the risk of drug resistance.

Parasite (Paris, France) 20110501

N-(heteroarenesulfonyl)prolinamides-catalyzed aldol reaction between acetone and aryl trihalomethyl ketones.

Organic letters 20110401

Physicochemical characterization of NPC 1161C, a novel antimalarial 8-aminoquinoline, in solution and solid state.

AAPS PharmSciTech 20110301

Methemoglobinemia caused by 8-aminoquinoline drugs: DFT calculations suggest an analogy to H4B's role in nitric oxide synthase.

Journal of the American Chemical Society 20110209

Rapid analysis of dried blood spot samples with sub-2-µm LC-MS/MS.

Bioanalysis 20110201

Identification of small molecule lead compounds for visceral leishmaniasis using a novel ex vivo splenic explant model system.

PLoS neglected tropical diseases 20110201

Identifying chelators for metalloprotein inhibitors using a fragment-based approach.

Journal of medicinal chemistry 20110127

Synthesis of substituted 8-aminoquinolines and phenanthrolines through a Povarov approach.

Organic & biomolecular chemistry 20110121

Evidence of the formation of direct covalent adducts of primaquine, 2-tert-butylprimaquine (NP-96) and monohydroxy metabolite of NP-96 with glutathione and N-acetylcysteine.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110101

Synthesis, antiprotozoal, antimicrobial, β-hematin inhibition, cytotoxicity and methemoglobin (MetHb) formation activities of bis(8-aminoquinolines).

Bioorganic & medicinal chemistry 20110101

Influence of climate and river level on the incidence of malaria in Cacao, French Guiana.

Malaria journal 20110101

A research agenda for malaria eradication: drugs.

PLoS medicine 20110101

The role of research in viral disease eradication and elimination programs: lessons for malaria eradication.

PLoS medicine 20110101

Towards an in vitro model of Plasmodium hypnozoites suitable for drug discovery.

PloS one 20110101

Structures, targets and recent approaches in anti-leishmanial drug discovery and development.

The open medicinal chemistry journal 20110101

Radical curative efficacy of tafenoquine combination regimens in Plasmodium cynomolgi-infected Rhesus monkeys (Macaca mulatta).

Malaria journal 20110101

Synthesis and pharmacological evaluation of some quinoline derivatives as potential cognition enhancers.

Arzneimittel-Forschung 20110101

Determinants of relapse periodicity in Plasmodium vivax malaria.

Malaria journal 20110101

Identification and characterization of genes involved in leishmania pathogenesis: the potential for drug target selection.

Molecular biology international 20110101

Primaquine in vivax malaria: an update and review on management issues.

Malaria journal 20110101

Prevalence and distribution of glucose-6-phosphate dehydrogenase (G6PD) variants in Thai and Burmese populations in malaria endemic areas of Thailand.

Malaria journal 20110101

Association of sub-microscopic malaria parasite carriage with transmission intensity in north-eastern Tanzania.

Malaria journal 20110101

Antileishmanial and antitrypanosomal activities of the 8-aminoquinoline tafenoquine.

Antimicrobial agents and chemotherapy 20101201

Mechanism of interaction of sitamaquine with Leishmania donovani.

The Journal of antimicrobial chemotherapy 20101201

Operational strategies to achieve and maintain malaria elimination.

Lancet (London, England) 20101106

Cascading transformations within a dynamic self-assembled system.

Nature chemistry 20100801

The effect of hematocrit on assay bias when using DBS samples for the quantitative bioanalysis of drugs.

Bioanalysis 20100801

From sensors to silencers: quinoline- and benzimidazole-sulfonamides as inhibitors for zinc proteases.

Journal of the American Chemical Society 20100623

Both visual and fluorescent sensor for Zn2+ based on quinoline platform.

Inorganic chemistry 20100503

The impact of phenotypic and genotypic G6PD deficiency on risk of plasmodium vivax infection: a case-control study amongst Afghan refugees in Pakistan.

PLoS medicine 20100501

Direct analysis of dried blood spots utilizing desorption electrospray ionization (DESI) mass spectrometry.

The Analyst 20100401

A systems-based analysis of Plasmodium vivax lifecycle transcription from human to mosquito.

PLoS neglected tropical diseases 20100401

Chloroquine and its derivatives exacerbate B19V-associated anemia by promoting viral replication.

PLoS neglected tropical diseases 20100401

Auxiliary-assisted palladium-catalyzed arylation and alkylation of sp2 and sp3 carbon-hydrogen bonds.

Journal of the American Chemical Society 20100324

Targeting the hypnozoite reservoir of Plasmodium vivax: the hidden obstacle to malaria elimination.

Trends in parasitology 20100301

Bis[2-(8-quinolylimino-meth-yl)phenolato-κN,N',O]iron(III) azide.

Acta crystallographica. Section E, Structure reports online 20100201

2,4-Dichloro-6-(8-quinolylamino-methyl-ene)cyclo-hexa-2,4-dien-1-one methanol solvate.

Acta crystallographica. Section E, Structure reports online 20100201

Control of visceral leishmaniasis in latin america-a systematic review.

PLoS neglected tropical diseases 20100101

Solid-phase extractors based on 8-aminoquinoline and 2-aminopyridine covalently bonded to silica gel for the selective separation and determination of calcium in natural water and pharmaceutical samples.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20100101

Treatment of visceral leishmaniasis.

Journal of global infectious diseases 20100101

Drug resistance in leishmaniasis.

Journal of global infectious diseases 20100101

The reality of using primaquine.

Malaria journal 20100101

Bis(N-triisopropyl-silyl-quinolin-8-aminato)nickel(II).

Acta crystallographica. Section E, Structure reports online 20100101

Structural modifications of quinoline-based antimalarial agents: Recent developments.

Journal of pharmacy & bioallied sciences 20100101

Palladium-catalyzed aryl C-H bonds activation/acetoxylation utilizing a bidentate system.

Organic letters 20091217

Direct quantitative bioanalysis of drugs in dried blood spot samples using a thin-layer chromatography mass spectrometer interface.

Analytical chemistry 20091215

Cytochrome P(450)-dependent toxic effects of primaquine on human erythrocytes.

Toxicology and applied pharmacology 20091115

Synthesis and characterization of organoaluminum compounds containing quinolin-8-amine derivatives and their catalytic behaviour for ring-opening polymerization of epsilon-caprolactone.

Dalton transactions (Cambridge, England : 2003) 20091107

Application of a liquid extraction based sealing surface sampling probe for mass spectrometric analysis of dried blood spots and mouse whole-body thin tissue sections.

Analytical chemistry 20091101

The synthesis and coordination chemistry of a tris-8-aminoquinoline tripodal ligand.

Dalton transactions (Cambridge, England : 2003) 20091021

Dichlorido[1-(8-quinolylimino-meth-yl)-2-naphtholato]iron(III).

Acta crystallographica. Section E, Structure reports online 20090701

N,N'-Di-8-quinolyladipamide.

Acta crystallographica. Section E, Structure reports online 20090601

Electrochemistry of ruthenium(II) complexes of 8-aminoquinoline.

Dalton transactions (Cambridge, England : 2003) 20090514

N-(2-hydroxypropyl)methacrylamide-amphotericin B (HPMA-AmB) copolymer conjugates as antileishmanial agents.

International journal of antimicrobial agents 20090501

Optimally timing primaquine treatment to reduce Plasmodium falciparum transmission in low endemicity Thai-Myanmar border populations.

Malaria journal 20090101

Electrospray ionization mass spectrometry as a valuable tool in the characterization of novel primaquine peptidomimetic derivatives.

European journal of mass spectrometry (Chichester, England) 20090101

Antimalarials and the fight against malaria in Brazil.

Therapeutics and clinical risk management 20090101

Synthesis, cytotoxic activity, and DNA binding properties of copper (II) complexes with hesperetin, naringenin, and apigenin.

Bioinorganic chemistry and applications 20090101

Visualisation and quantitative analysis of the rodent malaria liver stage by real time imaging.

PloS one 20090101

Pharmacotherapeutic options for visceral leishmaniasis-current scenario.

Clinical medicine. Pathology 20090101

Identification of differentially expressed genes after acute exposure to bulaquine (CDRI 80/53) in mice liver.

Basic & clinical pharmacology & toxicology 20081201

Selection of the most promising 2-substituted quinoline as antileishmanial candidate for clinical trials.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20081201

2-Nitro-N-(8-quinolyl)benzamide.

Acta crystallographica. Section E, Structure reports online 20081201

3-Nitro-N-(8-quinol-yl)benzamide.

Acta crystallographica. Section E, Structure reports online 20081201

4-Nitro-N-(8-quinol-yl)benzamide.

Acta crystallographica. Section E, Structure reports online 20081201

8-Iodo-quinolinium chloride dihydrate.

Acta crystallographica. Section E, Structure reports online 20081101

8-Iodo-quinolinium triiodide tetra-hydro-furan solvate.

Acta crystallographica. Section E, Structure reports online 20081101

Electrospray ionization-ion trap mass spectrometry study of PQAAPro and PQProAA mimetic derivatives of the antimalarial primaquine.

Journal of the American Society for Mass Spectrometry 20081001

Simulation-based cheminformatic analysis of organelle-targeted molecules: lysosomotropic monobasic amines.

Journal of computer-aided molecular design 20080901

In vitro antileishmanial activity of fluoro-artemisinin derivatives against Leishmania donovani.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080901

Toxicity in rhesus monkeys following administration of the 8-aminoquinoline 8-[(4-amino-l-methylbutyl)amino]- 5-(l-hexyloxy)-6-methoxy-4-methylquinoline (WR242511).

Journal of medical toxicology : official journal of the American College of Medical Toxicology 20080901

Effects of amino acids on malarial heme crystallization.

Biological & pharmaceutical bulletin 20080801

Clinical development of new prophylactic antimalarial drugs after the 5th Amendment to the Declaration of Helsinki.

Therapeutics and clinical risk management 20080801

8-Quinolylguanidinium chloride.

Acta crystallographica. Section E, Structure reports online 20080701

Selection and phenotype characterisation of sitamaquine-resistant promastigotes of Leishmania donovani.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080301

One-dimensional hydrogen-bonded structures in the 1:1 proton-transfer compounds of 4,5-dichlorophthalic acid with 8-hydroxyquinoline, 8-aminoquinoline and quinoline-2-carboxylic acid (quinaldic acid).

Acta crystallographica. Section C, Crystal structure communications 20080301

N,N'-Bis(8-quinol-yl)pyridine-2,6-dicarboxamide.

Acta crystallographica. Section E, Structure reports online 20080201

First dicyanamide-bridged spin-crossover coordination polymer: synthesis, structural, magnetic, and spectroscopic studies.

Chemistry (Weinheim an der Bergstrasse, Germany) 20080101

The role of anti-malarial drugs in eliminating malaria.

Malaria journal 20080101

Primaquine-induced differential gene expression analysis in mice liver using DNA microarrays.

Toxicology 20070924

Tafenoquine: a promising new antimalarial agent.

Expert opinion on investigational drugs 20070501

Response to malaria epidemics in Africa.

Emerging infectious diseases 20070501

DNA interaction of new copper(II) complexes with sulfonamides as ligands.

Journal of inorganic biochemistry 20070301

Interaction of sitamaquine with membrane lipids of Leishmania donovani promastigotes.

Biochimica et biophysica acta 20070201

Synthesis, antimalarial, antileishmanial, antimicrobial, cytotoxicity, and methemoglobin (MetHB) formation activities of new 8-quinolinamines.

Bioorganic & medicinal chemistry 20070115

Self-gelling primaquine-gum arabic conjugate: an injectable controlled delivery system for primaquine.

Biomacromolecules 20070101

8-Aminoquinolines: future role as antiprotozoal drugs.

Current opinion in infectious diseases 20061201

Drug development papers in PLoS Medicine: how we try to spot a winner.

PLoS medicine 20061201

Direct nitric oxide detection in aqueous solution by copper(II) fluorescein complexes.

Journal of the American Chemical Society 20061108

Synthesis and structures of acyclic monoanionic tetradentate aza beta-diketiminate complexes of magnesium, zinc, and cadmium.

Dalton transactions (Cambridge, England : 2003) 20061028

In-vitro and in-vivo studies on a topical formulation of sitamaquine dihydrochloride for cutaneous leishmaniasis.

The Journal of pharmacy and pharmacology 20060801

Novel acetoxylation and C-C coupling reactions at unactivated positions in alpha-amino acid derivatives.

Organic letters 20060720

Development and validation of a stability-indicating reversed-phase high performance liquid chromatography method for NPC 1161C, a novel 8-aminoquinoline anti-malarial drug.

Journal of chromatography. A 20060331

Visceral leishmaniasis (kala-azar): challenges ahead.

The Indian journal of medical research 20060301

Evaluation of immobilized metal-ion affinity chromatography for the fractionation of natural Cu complexing ligands.

Journal of chromatography. A 20051230

QZ1 and QZ2: rapid, reversible quinoline-derivatized fluoresceins for sensing biological Zn(II).

Journal of the American Chemical Society 20051207

A phase II dose-ranging study of sitamaquine for the treatment of visceral leishmaniasis in India.

The American journal of tropical medicine and hygiene 20051201

Clinical status of agents being developed for leishmaniasis.

Expert opinion on investigational drugs 20051101

A phase II dose-increasing study of sitamaquine for the treatment of visceral leishmaniasis in Kenya.

The American journal of tropical medicine and hygiene 20051101

Synthesis, antimalarial, antileishmanial, and antimicrobial activities of some 8-quinolinamine analogues.

Bioorganic & medicinal chemistry 20050715

Simple synthesis of aminoquinoline/ethylaniline copolymer semiconducting nanoparticles.

Chemistry (Weinheim an der Bergstrasse, Germany) 20050704

Isatin-Schiff base copper(II) complexes and their influence on cellular viability.

Journal of inorganic biochemistry 20050701

Prediction of genotoxicity of chemical compounds by statistical learning methods.

Chemical research in toxicology 20050601

[Therapeutic options for visceral leishmaniasis].

Medecine et maladies infectieuses 20050601

Modern malaria chemoprophylaxis.

Drugs 20050101

Randomized trial of 3-dose regimens of tafenoquine (WR238605) versus low-dose primaquine for preventing Plasmodium vivax malaria relapse.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20041015

Short report: the activity of pamaquine, an 8-aminoquinoline drug, against sporozoite-induced infections of Plasmodium vivax (New Guinea strains).

The American journal of tropical medicine and hygiene 20040801

Entrapment and release of quinoline derivatives using a hydrogel of a low molecular weight gelator.

Journal of controlled release : official journal of the Controlled Release Society 20040618

Ring-substituted quinolines as potential anti-tuberculosis agents.

Bioorganic & medicinal chemistry 20040515

Targetable water-soluble polymer-drug conjugates for the treatment of visceral leishmaniasis.

Journal of controlled release : official journal of the Controlled Release Society 20040108

Coordination chemistry of 2-(8-aminoquinolino)-4,6-di-tert-butylphenol with manganese(IV), iron(III), and cobalt(II/III):N,O-coordinated o-iminobenzosemiquinonate(1-) pi radical monoanions vs.o-iminophenolate(2-) dianions.

Dalton transactions (Cambridge, England : 2003) 20040107

8-Quinolinamines conjugated with amino acids are exhibiting potent blood-schizontocidal antimalarial activities.

Bioorganic & medicinal chemistry 20040102

Preparation and in vitro evaluation of primaquine-conjugated gum arabic microspheres.

Biomacromolecules 20040101

[Effects of two trypanosomicide drugs, gention violet and WR6026, on platelet concentrates preservation].

Revista da Sociedade Brasileira de Medicina Tropical 20040101

Visceral leishmaniasis with concomittant post kala-azar dermal leishmaniasis responds to oral sitamaquine: case report.

East African medical journal 20030801

Orally effective drugs for kala-azar (visceral leishmaniasis): focus on miltefosine and sitamaquine.

The Journal of the Association of Physicians of India 20030701

Blood schizontocidal activity of WR 238605 (Tafenoquine) against Plasmodium cynomolgi and Plasmodium fragile infections in rhesus monkeys.

Acta tropica 20030401

A randomized, double-blind, placebo-controlled, dose-ranging trial of tafenoquine for weekly prophylaxis against Plasmodium falciparum.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030301

Sitamaquine (GlaxoSmithKline/Walter Reed Army Institute).

Current opinion in investigational drugs (London, England : 2000) 20021001

Visceral leishmaniasis: current status of control, diagnosis, and treatment, and a proposed research and development agenda.

The Lancet. Infectious diseases 20020801

Chemistry of stable iminopropadienones, RN=C=C=C=O.

The Journal of organic chemistry 20020419

N-(ferrocenecarbonyl)-N'-(quinolin-8-yl)thiourea.

Acta crystallographica. Section C, Crystal structure communications 20020101

Mutagenic activity and mutational specificity of antiprotozoal drugs with and without nitrite treatment.

Environmental and molecular mutagenesis 20020101

Triangular test applied to the clinical trial of azithromycin against relapses in Plasmodium vivax infections.

Malaria journal 20020101

Compassionate use of sitamaquine in an HIV-positive patient with visceral leishmaniasis.

Transactions of the Royal Society of Tropical Medicine and Hygiene 20020101

Aminoquinolone WR6026 as a feasible substitute for gentian violet in Chagas' disease prophylaxis in preserved blood for transfusional purposes.

Revista da Sociedade Brasileira de Medicina Tropical 20020101

A new primaquine analogue, tafenoquine (WR 238605), for prophylaxis against Plasmodium falciparum malaria.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011215

N-(2-hydroxypropyl)methacrylamide (HPMA) copolymers for targeted delivery of 8-aminoquinoline antileishmanial drugs.

Journal of controlled release : official journal of the Controlled Release Society 20011213

Phase 2 trial of WR6026, an orally administered 8-aminoquinoline, in the treatment of visceral leishmaniasis caused by Leishmania chagasi.

The American journal of tropical medicine and hygiene 20011201

Effect of primaquine standard dose (15 mg/day for 14 days) in the treatment of vivax malaria patients in Thailand.

The Southeast Asian journal of tropical medicine and public health 20011201

Drug resistance in Indian visceral leishmaniasis.

Tropical medicine & international health : TM & IH 20011101

General rules for the packing of hydrogen-bonded crystals as derived from the analysis of squaric acid anions: aminoaromatic nitrogen base co-crystals.

Acta crystallographica. Section B, Structural science 20010801

Malaria chemoprophylaxis in the age of drug resistance. I. Currently recommended drug regimens.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010715

fac-Trichloro(quinolin-8-ylimido-N,N')(triphenylphosphine-P)rhenium(V).

Acta crystallographica. Section C, Crystal structure communications 20010501

Structural features of Plasmodium cytochrome b that may underlie susceptibility to 8-aminoquinolines and hydroxynaphthoquinones.

Molecular and biochemical parasitology 19930301