7,8-Dihydroxyflavone hydrate
Title | Journal |
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Pharmacological Bypass of Cockayne Syndrome B Function in Neuronal Differentiation. | Cell reports 20160322 |
7,8-Dihydroxyflavone, a TrkB agonist, attenuates behavioral abnormalities and neurotoxicity in mice after administration of methamphetamine. | Psychopharmacology 20140101 |
Optimization of a small tropomyosin-related kinase B (TrkB) agonist 7,8-dihydroxyflavone active in mouse models of depression. | Journal of medicinal chemistry 20121011 |
7,8-dihydroxyflavone rescues spatial memory and synaptic plasticity in cognitively impaired aged rats. | Journal of neurochemistry 20120801 |
Fear extinction and BDNF: translating animal models of PTSD to the clinic. | Genes, brain, and behavior 20120701 |
7,8-dihydroxyflavone induces G1 arrest of the cell cycle in U937 human monocytic leukemia cells via induction of the Cdk inhibitor p27 and downregulation of pRB phosphorylation. | Oncology reports 20120701 |
7,8-Dihydroxyflavone exhibits anti-inflammatory properties by downregulating the NF-κB and MAPK signaling pathways in lipopolysaccharide-treated RAW264.7 cells. | International journal of molecular medicine 20120601 |
7,8-dihydroxyflavone, a TrkB receptor agonist, blocks long-term spatial memory impairment caused by immobilization stress in rats. | Hippocampus 20120301 |
7,8-dihydroxyflavone exhibits therapeutic efficacy in a mouse model of Rett syndrome. | Journal of applied physiology (Bethesda, Md. : 1985) 20120301 |
The novel TrkB receptor agonist 7,8-dihydroxyflavone enhances neuromuscular transmission. | Muscle & nerve 20120201 |
7,8-dihydroxyflavone, a small-molecule TrkB agonist, reverses memory deficits and BACE1 elevation in a mouse model of Alzheimer's disease. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20120101 |
Activation of TrkB by 7,8-dihydroxyflavone prevents fear memory defects and facilitates amygdalar synaptic plasticity in aging. | Journal of Alzheimer's disease : JAD 20120101 |
A novel relationship between the radical-scavenging activity of flavonoids and enthalpy of formation revealed with Hartree-Fock computations and thermochemical deduction. | Redox report : communications in free radical research 20120101 |
Brain-derived neurotrophic factor enhances calcium regulatory mechanisms in human airway smooth muscle. | PloS one 20120101 |
Epigenetic enhancement of BDNF signaling rescues synaptic plasticity in aging. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111207 |
Vulnerability to depression: from brain neuroplasticity to identification of biomarkers. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110907 |
Antioxidant activity of 7,8-dihydroxyflavone provides neuroprotection against glutamate-induced toxicity. | Neuroscience letters 20110725 |
Effect of 7,8-dihydroxyflavone, a small-molecule TrkB agonist, on emotional learning. | The American journal of psychiatry 20110201 |
Toward neurotrophin-based therapeutics. | The American journal of psychiatry 20110201 |
Behavioral and endocrine consequences of simultaneous exposure to two different stressors in rats: interaction or independence? | PloS one 20110101 |
Structure of flavonoids influences the degree inhibition of Benzo(a)pyrene - induced DNA damage and micronuclei in HepG2 cells. | Neoplasma 20110101 |
Synergistic activation of dopamine D1 and TrkB receptors mediate gain control of synaptic plasticity in the basolateral amygdala. | PloS one 20110101 |
Structure-function relationships of inhibition of human cytochromes P450 1A1, 1A2, 1B1, 2C9, and 3A4 by 33 flavonoid derivatives. | Chemical research in toxicology 20101220 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Characterization of an O-methyltransferase from Streptomyces avermitilis MA-4680. | Journal of microbiology and biotechnology 20100901 |
An efficient and economical MTT assay for determining the antioxidant activity of plant natural product extracts and pure compounds. | Journal of natural products 20100723 |
[Effect of seven kinds of flavonoids on recombinant human protein tyrosine phosphatase]. | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20100501 |
A selective TrkB agonist with potent neurotrophic activities by 7,8-dihydroxyflavone. | Proceedings of the National Academy of Sciences of the United States of America 20100209 |
Reliability of bond dissociation enthalpy calculated by the PM6 method and experimental TEAC values in antiradical QSAR of flavonoids. | Bioorganic & medicinal chemistry 20100101 |
Deoxygedunin, a natural product with potent neurotrophic activity in mice. | PloS one 20100101 |
Effects of brain-derived neurotrophic factor on local inflammation in experimental stroke of rat. | Mediators of inflammation 20100101 |
Acidity of hydroxyl groups: an overlooked influence on antiradical properties of flavonoids. | The Journal of organic chemistry 20090403 |
Preventive effect of 7,8-dihydroxyflavone against oxidative stress induced genotoxicity. | Biological & pharmaceutical bulletin 20090201 |
Empirically predicted 13C NMR chemical shifts for 8-hydroxyflavone starting from 7,8,4'-trihydroxyflavone and from 7,8-dihydroxyflavone. | Magnetic resonance in chemistry : MRC 20080701 |
Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods. | Journal of molecular graphics & modelling 20061101 |
Human NAD(P)H:quinone oxidoreductase inhibition by flavonoids in living cells. | Free radical biology & medicine 20050715 |
Catecholic flavonoids acting as telomerase inhibitors. | Journal of medicinal chemistry 20041216 |
A flexible data analysis tool for chemical genetic screens. | Chemistry & biology 20041101 |
P53 hot-spot mutants are resistant to ubiquitin-independent degradation by increased binding to NAD(P)H:quinone oxidoreductase 1. | Proceedings of the National Academy of Sciences of the United States of America 20031209 |
Different catalytic properties and inhibitor responses of the goldfish brain and ovary aromatase isozymes. | General and comparative endocrinology 20010801 |
Flavonolignan and flavone inhibitors of a Staphylococcus aureus multidrug resistance pump: structure-activity relationships. | Journal of medicinal chemistry 20010118 |
Steroid hormone activity of flavonoids and related compounds. | Breast cancer research and treatment 20000701 |
Anti-AIDS agents, 10. Acacetin-7-O-beta-D-galactopyranoside, an anti-HIV principle from Chrysanthemum morifolium and a structure-activity correlation with some related flavonoids. | Journal of natural products 19940101 |
Flavones are inhibitors of HIV-1 proteinase. | Biochemical and biophysical research communications 19921030 |
Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases. | European journal of biochemistry 19900705 |