Home Other Building Blocks 4-Hydroxy-2-mercapto-6-methylpyrimidine

4-Hydroxy-2-mercapto-6-methylpyrimidine

CAS No.:
56-04-2
Catalog Number:
AG0034DF
Molecular Formula:
C5H6N2OS
Molecular Weight:
142.1789
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
50g
98%
In Stock USA
United States
$43
- +
250g
98%
In Stock USA
United States
$121
- +
Product Description
Catalog Number:
AG0034DF
Chemical Name:
4-Hydroxy-2-mercapto-6-methylpyrimidine
CAS Number:
56-04-2
Molecular Formula:
C5H6N2OS
Molecular Weight:
142.1789
MDL Number:
MFCD00006040
IUPAC Name:
6-methyl-2-sulfanylidene-1H-pyrimidin-4-one
InChI:
InChI=1S/C5H6N2OS/c1-3-2-4(8)7-5(9)6-3/h2H,1H3,(H2,6,7,8,9)
InChI Key:
HWGBHCRJGXAGEU-UHFFFAOYSA-N
SMILES:
Cc1cc(O)nc(n1)S
EC Number:
200-252-3
UNII:
QW24888U5F
UN Number:
3077
Properties
Complexity:
197  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
142.02g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
142.176g/mol
Monoisotopic Mass:
142.02g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
73.2A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.2  
Literature
Title Journal
Anti-inflammatory effects of methylthiouracil in vitro and in vivo. Toxicology and applied pharmacology 20151101
Electron configuration and hydrogen-bonding pattern in several thymine and uracil analogues studied by 1H-14N NQDR and DFT/QTAIM. The journal of physical chemistry. B 20120802
Identifying chelators for metalloprotein inhibitors using a fragment-based approach. Journal of medicinal chemistry 20110127
Vasculoprotective effects of rosiglitazone through modulating renin-angiotensin system in vivo and vitro. Cardiovascular diabetology 20110101
Optimization and Validation of RP-HPLC-UV/Vis Method for Determination Phenolic Compounds in Several Personal Care Products. International journal of analytical chemistry 20110101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Interaction of antithyroid drugs with bovine serum albumin: electrophoretic and fluorimetric study. Journal of pharmaceutical sciences 20100301
Antithyroid drugs and their analogues protect against peroxynitrite-mediated protein tyrosine nitration--a mechanistic study. Chemistry (Weinheim an der Bergstrasse, Germany) 20100125
Determination of thyreostatics in animal feeds by CE with electrochemical detector. Electrophoresis 20091001
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Influence of thioketo substitution on the properties of uracil and its noncovalent interactions with alkali metal ions: threshold collision-induced dissociation and theoretical studies. The journal of physical chemistry. A 20060202
Bioinorganic chemistry in thyroid gland: effect of antithyroid drugs on peroxidase-catalyzed oxidation and iodination reactions. Bioinorganic chemistry and applications 20060101
First example of mu(3)-sulfido bridged mixed-valent triruthenium complex triangle Ru(III)(2)Ru(II)(O,O-acetylacetonate)(3)(mu-O,O,gamma-C-acetylacetonate)(3)(mu(3)-S) (1) incorporating simultaneous O,O- and gamma-C-bonded bridging acetylacetonate units. Synthesis, crystal structure, and spectral and redox properties. Inorganic chemistry 20030224
Carbon fiber cylindrical microelectrode-based detector for the determination of antithyroid drugs. Talanta 20020304
Method for the analysis of thyreostats in meat tissue using gas chromatography with nitrogen phosphorus detection and tandem mass spectrometric confirmation. Journal of chromatographic science 20010501
Thiouracil antithyroid drugs as a new class of neuronal nitric oxide synthase inhibitors. Biochemical and biophysical research communications 20010406
Structure-activity relationship of ligands of uracil phosphoribosyltransferase from Toxoplasma gondii. Biochemical pharmacology 19940817
Aplastic anaemia after propylthiouracil. Lancet (London, England) 19680622
Properties