5,6-Dimethylbenzimidazole
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Anaerobic biosynthesis of the lower ligand of vitamin B12. | Proceedings of the National Academy of Sciences of the United States of America 20150825 |
Electronic spectroscopy and computational studies of glutathionylco(III)balamin. | The journal of physical chemistry. A 20120628 |
Active site residues critical for flavin binding and 5,6-dimethylbenzimidazole biosynthesis in the flavin destructase enzyme BluB. | Protein science : a publication of the Protein Society 20120601 |
Tris(5,6-dimethyl-1H-benzimidazole-κN(3))(pyridine-2,6-dicarboxyl-ato-κ(3)O(2),N,O(6))nickel(II). | Acta crystallographica. Section E, Structure reports online 20120601 |
Improvement of adenosylcobalamin production by metabolic control strategy in Propionibacterium freudenreichii. | Applied biochemistry and biotechnology 20120501 |
Synthesis and biological evaluation of benzo[d]imidazole derivatives as potential anti-cancer agents. | Bioorganic & medicinal chemistry letters 20120201 |
Immobilised vitamin B12 as a biomimetic model for base-off/histidine-on coordination. | Chemical communications (Cambridge, England) 20111028 |
Intermediate-assisted multifunctional catalysis in the conversion of flavin to 5,6-dimethylbenzimidazole by BluB: a density functional theory study. | Journal of the American Chemical Society 20110323 |
Navigating the human metabolome for biomarker identification and design of pharmaceutical molecules. | Journal of biomedicine & biotechnology 20110101 |
Novel benzyl-substituted N-heterocyclic carbene-silver acetate complexes: synthesis, cytotoxicity and antibacterial studies. | Metallomics : integrated biometal science 20110101 |
A nuclear magnetic resonance based approach to accurate functional annotation of putative enzymes in the methanogen Methanosarcina acetivorans. | BMC genomics 20110101 |
Redetermination of the X-ray structure of nitroxylcobalamin: base-on nitroxylcobalamin exhibits a remarkably long Co-N(dimethylbenzimidazole) bond distance. | Dalton transactions (Cambridge, England : 2003) 20101128 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Genetic disorders of vitamin B₁₂ metabolism: eight complementation groups--eight genes. | Expert reviews in molecular medicine 20101101 |
Sirtuin chemical mechanisms. | Biochimica et biophysica acta 20100801 |
Thermolability of mutant MMACHC protein in the vitamin B12-responsive cblC disorder. | Molecular genetics and metabolism 20100501 |
(E)-1,2-Bis(1-propyl-5,6-dimethyl-1H-benzimidazol-2-yl)ethene. | Acta crystallographica. Section E, Structure reports online 20100301 |
Purification and some properties of wild-type and N-terminal-truncated ethanolamine ammonia-lyase of Escherichia coli. | Journal of biochemistry 20100101 |
Toxicology and drug delivery by cucurbit[n]uril type molecular containers. | PloS one 20100101 |
The cobinamide amidohydrolase (cobyric acid-forming) CbiZ enzyme: a critical activity of the cobamide remodelling system of Rhodobacter sphaeroides. | Molecular microbiology 20091201 |
Structure-based mechanism of ADP-ribosylation by sirtuins. | The Journal of biological chemistry 20091127 |
Apparent ruminal synthesis and intestinal disappearance of vitamin B12 and its analogs in dairy cows. | Journal of dairy science 20090901 |
(N-n-Butyl-pyridine-4-carbothio-amide-κN)chloridobis(dimethyl-glyoximato-κN,N')cobalt(III) hemihydrate. | Acta crystallographica. Section E, Structure reports online 20090701 |
Stabilization of the base-off forms of vitamin B(12) and coenzyme B(12) by encapsulation of the alpha-axial 5,6-dimethylbenzimidazole ligand with cucurbit[7]uril. | Dalton transactions (Cambridge, England : 2003) 20090514 |
Residue Phe112 of the human-type corrinoid adenosyltransferase (PduO) enzyme of Lactobacillus reuteri is critical to the formation of the four-coordinate Co(II) corrinoid substrate and to the activity of the enzyme. | Biochemistry 20090414 |
NMR spectroscopy and molecular modelling studies of nitrosylcobalamin: further evidence that the deprotonated, base-off form is important for nitrosylcobalamin in solution. | Dalton transactions (Cambridge, England : 2003) 20090121 |
[Effect of a corrinoid on Methanosarcina barkeri DNA synthesis]. | Mikrobiologiia 20090101 |
Ag4L2 nanocage as a building unit toward the construction of silver metal strings. | Inorganic chemistry 20081117 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. | Journal of medicinal chemistry 20081113 |
Metabolism of halophilic archaea. | Extremophiles : life under extreme conditions 20080301 |
Identification of metabolites with anticancer properties by computational metabolomics. | Molecular cancer 20080101 |
Medical implications of benzimidazole derivatives as drugs designed for targeting DNA and DNA associated processes. | Current medicinal chemistry 20080101 |
Analysis of vibrational spectra of 5,6-dimethyl benzimidazole based on density functional theory calculations. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20071101 |
Pseudovitamin B(12) is the corrinoid produced by Lactobacillus reuteri CRL1098 under anaerobic conditions. | FEBS letters 20071016 |
The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors. | Bioorganic & medicinal chemistry 20070515 |
X-ray structural characterization of imidazolylcobalamin and histidinylcobalamin: cobalamin models for aquacobalamin bound to the B12 transporter protein transcobalamin. | Inorganic chemistry 20070430 |
Biochemistry: molecular cannibalism. | Nature 20070322 |
BluB cannibalizes flavin to form the lower ligand of vitamin B12. | Nature 20070322 |
The enzymatic activation of coenzyme B12. | Dalton transactions (Cambridge, England : 2003) 20060307 |
Differentiation of ionised benzimidazole from its isomeric alpha-distonic ion by collision-induced dissociation and neutralisation-reionisation mass spectrometry. | European journal of mass spectrometry (Chichester, England) 20050101 |
Solution structure and thermolysis of Cobeta-5'-deoxyadenosylimidazolylcobamide, a coenzyme B12 analogue with an imidazole axial nucleoside. | Inorganic chemistry 20041213 |
Spectroscopic and computational studies on the adenosylcobalamin-dependent methylmalonyl-CoA mutase: evaluation of enzymatic contributions to Co-C bond activation in the Co3+ ground state. | Journal of the American Chemical Society 20040707 |
Cobalamin-dependent methionine synthase: probing the role of the axial base in catalysis of methyl transfer between methyltetrahydrofolate and exogenous cob(I)alamin or cob(I)inamide. | Biochemistry 20031216 |
Reactions of nitric oxide with vitamin B12 and its precursor, cobinamide. | Biochemistry 20030729 |
Formation of the dimethylbenzimidazole ligand of coenzyme B(12) under physiological conditions by a facile oxidative cascade. | Organic letters 20030626 |
Spectroscopic and computational studies of Co3+-corrinoids: spectral and electronic properties of the B12 cofactors and biologically relevant precursors. | Journal of the American Chemical Society 20030514 |
Alpha-5,6-dimethylbenzimidazole adenine dinucleotide (alpha-DAD), a putative new intermediate of coenzyme B12 biosynthesis in Salmonella typhimurium. | Microbiology (Reading, England) 20030401 |
The crystal structure of coenzyme B12-dependent glycerol dehydratase in complex with cobalamin and propane-1,2-diol. | European journal of biochemistry 20020901 |
Synthesis of adenosylcobinamide 2-chlorophenyl phosphate, a zwitterionic cobinamide phosphate analog of adenosylcobalamin en route to crystallizable cobinamides. | Journal of inorganic biochemistry 20020815 |
Enzymatic activity of coenzyme B(12) derivatives with altered axial nucleotides: probing the mechanochemical triggering hypothesis in ribonucleotide reductase. | Inorganic chemistry 20011105 |
Equilibrium and kinetic studies on the reactions of alkylcobalamins with cyanide. | Inorganic chemistry 20011008 |
Structural investigation of the biosynthesis of alternative lower ligands for cobamides by nicotinate mononucleotide: 5,6-dimethylbenzimidazole phosphoribosyltransferase from Salmonella enterica. | The Journal of biological chemistry 20011005 |
Renal interstitial cGMP mediates natriuresis by direct tubule mechanism. | Hypertension (Dallas, Tex. : 1979) 20010901 |
Assessment of the existence of hyper-long axial Co(II)-N bonds in cobinamide B(12) models by using electron paramagnetic resonance spectroscopy. | Journal of the American Chemical Society 20010411 |
Thermodynamic and kinetic studies on the reaction between the vitamin B12 derivative beta-(N-methylimidazolyl)cobalamin and N-methylimidazole: ligand displacement at the alpha axial site of cobalamins. | Inorganic chemistry 20010326 |
Molecular modeling of the mechanochemical triggering mechanism for catalysis of carbon-cobalt bond homolysis in coenzyme B12. | Journal of inorganic biochemistry 20010115 |