5,5-Dimethyl-1-pyrroline N-oxide
Title | Journal |
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An evaluation of myeloperoxidase-mediated bio-activation of NSAIDs in promyelocytic leukemia (HL-60) cells for potential cytotoxic selectivity. | Toxicology letters 20171005 |
Phenylbutazone Oxidation via Cu,Zn-SOD Peroxidase Activity: An EPR Study. | Chemical research in toxicology 20150720 |
Guest inclusion in cucurbiturils studied by ESR and DFT: the case of nitroxide radicals and spin adducts of DMPO and MNP. | The journal of physical chemistry. A 20120823 |
Inhibition of ROS-induced apoptosis in endothelial cells by nitrone spin traps via induction of phase II enzymes and suppression of mitochondria-dependent pro-apoptotic signaling. | Biochemical pharmacology 20120815 |
Post-trapping derivatization of radical-derived EPR-silent adducts: application to free radical detection by HPLC/UV in chemical, biochemical, and biological systems and comparison with EPR spectroscopy. | Analytical chemistry 20120807 |
Measurement of intracellular biomolecular oxidation in liver ischemia-reperfusion injury via immuno-spin trapping. | Free radical biology & medicine 20120801 |
Free radical-operated proteotoxic stress in macrophages primed with lipopolysaccharide. | Free radical biology & medicine 20120701 |
The spin trap 5,5-dimethyl-1-pyrroline N-oxide inhibits lipopolysaccharide-induced inflammatory response in RAW 264.7 cells. | Life sciences 20120310 |
On the efficiency of water soluble antioxidants. | Ultrasonics sonochemistry 20120301 |
Measuring sunscreen protection against solar-simulated radiation-induced structural radical damage to skin using ESR/spin trapping: development of an ex vivo test method. | Free radical research 20120301 |
Identification of isomeric spin adducts of Leu-Tyr and Tyr-Leu free radicals using liquid chromatography-tandem mass spectrometry. | Biomedical chromatography : BMC 20120101 |
The plasma membrane is involved in the visible light-tissue interaction. | Photomedicine and laser surgery 20120101 |
Detoxification of 6-hydroxydopamine-induced dopaminergic neurodegeneration by 5,5-dimethyl-1-pyrroline N-oxide, a radical trapper, in hemiparkinsonian rats. | Biological & pharmaceutical bulletin 20120101 |
Evaluation of the Forrester-Hepburn mechanism as an artifact source in ESR spin-trapping. | Chemical research in toxicology 20111219 |
Oxidative stress studies of six TiO₂ and two CeO₂ nanomaterials: immuno-spin trapping results with DNA. | Nanotoxicology 20111201 |
Isolated Hb Providence β82Asn and β82Asp fractions are more stable than native HbA(0) under oxidative stress conditions. | Biochemistry 20111115 |
Direct assessment of the antioxidant properties of midazolam by electron spin resonance spectroscopy. | Journal of anesthesia 20111001 |
Kinetic analysis of reactive oxygen species generated by the in vitro reconstituted NADPH oxidase and xanthine oxidase systems. | Journal of biochemistry 20110801 |
Studies on the photosensitized reduction of resorufin and implications for the detection of oxidative stress with Amplex Red. | Free radical biology & medicine 20110701 |
Evaluation of superoxide anion radicals generated from an aqueous extract of particulate phase cigarette smoke by electron spin resonance using 5,5-dimethyl-1-pyrroline-N-oxide. | Bioscience, biotechnology, and biochemistry 20110101 |
Biotinylated analogue of the spin-trap 5,5-dimethyl-1-pyrroline-N-oxide for the detection of low-abundance protein radicals by mass spectrometry. | Analytical chemistry 20101115 |
Detailed analysis of reactive oxygen species induced by visible light in various cell types. | Lasers in surgery and medicine 20100801 |
(Bi)sulfite oxidation by copper, zinc-superoxide dismutase: Sulfite-derived, radical-initiated protein radical formation. | Environmental health perspectives 20100701 |
Effect of 2, 5-substituents on the stability of cyclic nitrone superoxide spin adducts: A density functional theory approach. | Free radical research 20100701 |
Myeloperoxidase-induced genomic DNA-centered radicals. | The Journal of biological chemistry 20100625 |
Using cyclodextrins to encapsulate oxygen-centered and carbon-centered radical adducts: the case of DMPO, PBN, and MNP spin traps. | The journal of physical chemistry. A 20100603 |
Reactions of superoxide with the myoglobin tyrosyl radical. | Free radical biology & medicine 20100601 |
Investigating the mechanisms of aromatic amine-induced protein free radical formation by quantitative structure-activity relationships: implications for drug-induced agranulocytosis. | Chemical research in toxicology 20100517 |
Peroxynitrite-mediated oxidative modifications of complex II: relevance in myocardial infarction. | Biochemistry 20100323 |
Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide. 6. Redox properties. | The journal of physical chemistry. A 20100121 |
New heteroaryl nitrones with spin trap properties: Identification of a 4-furoxanyl derivative with excellent properties to be used in biological systems. | Bioorganic & medicinal chemistry 20100115 |
Spin trapping of radicals other than the *OH radical upon reduction of the anticancer agent tirapazamine by cytochrome P450 reductase. | Journal of the American Chemical Society 20091014 |
Molecular mechanisms underlying the flavonoid-induced inhibition of alpha-synuclein fibrillation. | Biochemistry 20090901 |
The fate of free radicals in a cellulose based hydrogel: detection by electron paramagnetic resonance spectroscopy. | Journal of pharmaceutical sciences 20090701 |
Comparison of superoxide detection abilities of newly developed spin traps in the living cells. | Free radical research 20090701 |
Arsenic induces telomerase expression and maintains telomere length in human cord blood cells. | Toxicology 20090616 |
Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide. 5. Thermodynamics and kinetics of unimolecular decomposition. | The journal of physical chemistry. A 20090604 |
The radical trap 5,5-dimethyl-1-pyrroline N-oxide exerts dose-dependent protection against myocardial ischemia-reperfusion injury through preservation of mitochondrial electron transport. | The Journal of pharmacology and experimental therapeutics 20090501 |
Thermal generation of stable SO4*- spin trap adducts with super-hyperfine structure in their EPR spectra: an alternative EPR spin trapping assay for radical scavenging capacity determination in dimethylsulphoxide. | Free radical research 20090501 |
Pharmaco/ferrokinetic-related pro-oxidant activity of deferiprone in beta-thalassemia. | Free radical research 20090501 |
Inhibitory effect of antioxidants on hydroxyl radical generation from methylguanidine: an ESR study. | Neurochemical research 20090401 |
Immuno-spin trapping of protein and DNA radicals: 'tagging' free radicals to locate and understand the redox process. | Free radical biology & medicine 20090401 |
Degradation of high-molar-mass hyaluronan by ascorbate plus cupric ions: effects of D-penicillamine addition. | Chemistry & biodiversity 20090301 |
Immuno-spin trapping of a post-translational carboxypeptidase B1 radical formed by a dual role of xanthine oxidase and endothelial nitric oxide synthase in acute septic mice. | Free radical biology & medicine 20090215 |
Studies toward the analysis of S-nitrosoproteins. | Organic & biomolecular chemistry 20090121 |
Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide. 4. Conformational effects on the EPR hyperfine splitting constants. | The journal of physical chemistry. A 20081211 |
Identification of free radicals induced by UV irradiation in collagen water solutions. | Journal of photochemistry and photobiology. B, Biology 20081113 |
Spin trapping investigation of peroxide- and isoniazid-induced radicals in Mycobacterium tuberculosis catalase-peroxidase. | Biochemistry 20081028 |
Identification of protein radicals formed in the human neuroglobin-H2O2 reaction using immuno-spin trapping and mass spectrometry. | Biochemistry 20080930 |
Extensive screening for edible herbal extracts with potent scavenging activity against superoxide anions. | Plant foods for human nutrition (Dordrecht, Netherlands) 20080601 |
Mechanisms involved in A2E oxidation. | Experimental eye research 20080601 |
Assessment of genotoxicity of methyl-tert-butyl ether, benzene, toluene, ethylbenzene, and xylene to human lymphocytes using comet assay. | Journal of hazardous materials 20080501 |
Mechanistic studies of the reactions of nitrone spin trap PBN with glutathiyl radical. | The journal of physical chemistry. B 20080417 |
Ascorbate interacts with reduced glutathione to scavenge phenoxyl radicals in HL60 cells. | Free radical biology & medicine 20080415 |
Direct mitochondrial dysfunction precedes reactive oxygen species production in amiodarone-induced toxicity in human peripheral lung epithelial HPL1A cells. | Toxicology and applied pharmacology 20080315 |
Ciclopirox olamine directly scavenges hydroxyl radical. | International journal of dermatology 20080101 |
Reaction of the carbonate radical with the spin-trap 5,5-dimethyl-1-pyrroline-N-oxide in chemical and cellular systems: pulse radiolysis, electron paramagnetic resonance, and kinetic-competition studies. | Free radical biology & medicine 20071201 |
Structure-activity relationship of C6-C3 phenylpropanoids on xanthine oxidase-inhibiting and free radical-scavenging activities. | Free radical biology & medicine 20071201 |
Superoxide dismutase enhanced the formation of hydroxyl radicals in a reaction mixture containing xanthone under UVA irradiation. | Bioscience, biotechnology, and biochemistry 20071201 |
UVA photoirradiation of anhydroretinol--formation of singlet oxygen and superoxide. | Toxicology and industrial health 20071101 |
Investigation of the generation of hydroxyl radicals and their oxidative role in the presence of heterogeneous copper catalysts. | Chemosphere 20071001 |
Iron-chelating agents never suppress Fenton reaction but participate in quenching spin-trapped radicals. | Analytica chimica acta 20070919 |
Aminoglutethimide-induced protein free radical formation on myeloperoxidase: a potential mechanism of agranulocytosis. | Chemical research in toxicology 20070701 |
Red light-induced redox reactions in cells observed with TEMPO. | Photomedicine and laser surgery 20070601 |
Sulfite-radical anions in isolated soy proteins. | Journal of food science 20070601 |
DMPO-OH radical formation from 5,5-dimethyl-1-pyrroline N-oxide (DMPO) in hot water. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070201 |
Theoretical and experimental studies of the spin trapping of inorganic radicals by 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 2. Carbonate radical anion. | The journal of physical chemistry. A 20070118 |
Immuno-spin trapping analyses of DNA radicals. | Nature protocols 20070101 |
Cadaverine protects Vibrio vulnificus from superoxide stress. | Journal of microbiology and biotechnology 20070101 |
Theoretical and experimental studies of the spin trapping of inorganic radicals by 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 1. Carbon dioxide radical anion. | The journal of physical chemistry. A 20061214 |
Caffeine metabolites are inhibitors of the nuclear enzyme poly(ADP-ribose)polymerase-1 at physiological concentrations. | Biochemical pharmacology 20060928 |
Azelnidipine, a new calcium channel blocker, inhibits endothelial inflammatory response by reducing intracellular levels of reactive oxygen species. | European journal of pharmacology 20060928 |
Protein radical formation on thyroid peroxidase during turnover as detected by immuno-spin trapping. | Free radical biology & medicine 20060801 |
Inactivation of bacteria G(+)-S. aureus and G(-)-E. coli by phototoxic polythiophene incorporated in ZSM-5 zeolite. | Chemosphere 20060601 |
High static pressure alters spin trapping rates in solution. Dependence on the structure of nitrone spin traps. | Organic & biomolecular chemistry 20060307 |
Immuno-spin trapping of DNA radicals. | Nature methods 20060201 |
Beneficial effects of ascorbic acid on heat-induced fish gel (Kamaboko) from the superoxide anion radical. | Bioscience, biotechnology, and biochemistry 20060201 |
Hypoxic reperfusion of the ischemic heart and oxygen radical generation. | American journal of physiology. Heart and circulatory physiology 20060101 |
Vanadium promotes hydroxyl radical formation by activated human neutrophils. | Free radical biology & medicine 20060101 |
Influence of complexation with cyclodextrins on photo-induced free radical production by the common sunscreen agents octyl-dimethylaminobenzoate and octyl-methoxycinnamate. | Die Pharmazie 20060101 |
Detection of reactive free radicals derived from nucleosides by liquid chromatography coupled to tandem mass spectrometry of DMPO spin trapping adducts. | Rapid communications in mass spectrometry : RCM 20060101 |
Intramolecular electron transfer between tyrosyl radical and cysteine residue inhibits tyrosine nitration and induces thiyl radical formation in model peptides treated with myeloperoxidase, H2O2, and NO2-: EPR SPIN trapping studies. | The Journal of biological chemistry 20051209 |
Superoxide generation from mitochondrial NADH dehydrogenase induces self-inactivation with specific protein radical formation. | The Journal of biological chemistry 20051111 |
Immunochemical detection of nitric oxide and nitrogen dioxide trapping of the tyrosyl radical and the resulting nitrotyrosine in sperm whale myoglobin. | Free radical biology & medicine 20051015 |
Free radical generation during chemical depolymerization of heparin. | Analytical biochemistry 20050915 |
Nitric oxide release from the unimolecular decomposition of the superoxide radical anion adduct of cyclic nitrones in aqueous medium. | Organic & biomolecular chemistry 20050907 |
Characterization of the high-resolution ESR spectra of superoxide radical adducts of 5-(diethoxyphosphoryl)-5-methyl-1-pyrroline N-oxide (DEPMPO) and 5,5-dimethyl-1-pyrroline N-oxide (DMPO). Analysis of conformational exchange. | Free radical research 20050801 |
Acoustic cavitation in phacoemulsification and the role of antioxidants. | Ultrasound in medicine & biology 20050801 |
Copper-catalyzed protein oxidation and its modulation by carbon dioxide: enhancement of protein radicals in cells. | The Journal of biological chemistry 20050722 |
ESR spin trapping of a carbon-centered free radical from agonist-stimulated human platelets. | Free radical biology & medicine 20050715 |
Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline n-oxide (DMPO). 1. The thermodynamics of formation and its acidity. | The journal of physical chemistry. A 20050714 |
Superoxide radical anion adduct of 5,5-dimethyl-1-pyrroline N-oxide (DMPO). 2. The thermodynamics of decay and EPR spectral properties. | The journal of physical chemistry. A 20050714 |
5,5-Dimethyl-2-pyrrolidone-N-oxyl formation in electron spin resonance studies of electrolyzed NaCl solution using 5,5-dimethyl-1-pyrroline-N-oxide as a spin trapping agent. | Journal of agricultural and food chemistry 20050615 |
Study of the oxidative stress in a rat model of chronic brain hypoperfusion. | Neurochemistry international 20050601 |
Identification of the myoglobin tyrosyl radical by immuno-spin trapping and its dimerization. | Free radical biology & medicine 20050401 |
Photochemistry of naphthalene diimides: EPR study of free radical formation via photoredox process. | Photochemistry and photobiology 20050101 |
Protective effect of egg yolk phosvitin against ultraviolet- light-induced lipid peroxidation in the presence of iron ions. | Biological trace element research 20050101 |
Inhibition of LPS-stimulated NO production in mouse macrophage-like cells by azulenequinones. | Anticancer research 20050101 |
Production of the carbonate radical anion during xanthine oxidase turnover in the presence of bicarbonate. | The Journal of biological chemistry 20041210 |
Involvement of protein radical, protein aggregation, and effects on NO metabolism in the hypochlorite-mediated oxidation of mitochondrial cytochrome c. | Free radical biology & medicine 20041115 |
Novel identification of a sulfur-centered, radical-derived 5,5-dimethyl-1-pyrroline N-oxide nitrone adduct formed from the oxidation of DTT by LC/ELISA, LC/electrospray ionization-MS, and LC/tandem MS. | Chemical research in toxicology 20041101 |
Inhibition of BPA degradation by serum as a hydroxyl radical scavenger and an Fe trapping agent in Fenton process. | Chemosphere 20041001 |
Electron spin resonance study of phosphorus-nitroxides from 1,3-additions of silicon-phosphorus reagents to nitrones. | Magnetic resonance in chemistry : MRC 20041001 |
Using anti-5,5-dimethyl-1-pyrroline N-oxide (anti-DMPO) to detect protein radicals in time and space with immuno-spin trapping. | Free radical biology & medicine 20040515 |
Conversion of the 2,2,6,6-tetramethylpiperidine moiety to a 2,2-dimethylpyrrolidine by cytochrome P450: evidence for a mechanism involving nitroxide radicals and heme iron. | Biochemistry 20040511 |
Mechanism of hydroxyl radical scavenging by rebamipide: identification of mono-hydroxylated rebamipide as a major reaction product. | Free radical research 20040501 |
Hydroxyl radical generation caused by the reaction of singlet oxygen with a spin trap, DMPO, increases significantly in the presence of biological reductants. | Free radical research 20040401 |
Theoretical study of the spin trapping of hydroxyl radical by cyclic nitrones: a density functional theory approach. | Journal of the American Chemical Society 20040218 |
The reaction rate of edaravone (3-methyl-1-phenyl-2-pyrazolin-5-one (MCI-186)) with hydroxyl radical. | Chemical & pharmaceutical bulletin 20040201 |
Both the D-(+) and L-(-) enantiomers of nicotine inhibit Abeta aggregation and cytotoxicity. | Biochemistry 20040127 |
Enzymatic and nonenzymatic formation of reactive oxygen species from 6-anilino-5,8-quinolinequinone. | Biochimica et biophysica acta 20040105 |
Effects of uvalino, a new autochthonous wine, on the inhibition of the production of hydroxyl radicals. | Drugs under experimental and clinical research 20040101 |
Flow-injection EPR investigation on OH radical scavenging activity of Gd(III) containing MRI contrast media. | Journal of medicine 20040101 |
Repressions of actin assembly and RhoA localization are involved in inhibition of tumor cell motility by lipophilic ascorbyl phosphate. | International journal of oncology 20031201 |
Formation of superoxide anion during ferrous ion-induced decomposition of linoleic acid hydroperoxide under aerobic conditions. | Journal of biochemistry 20031201 |
Reaction of human hemoglobin with peroxynitrite. Isomerization to nitrate and secondary formation of protein radicals. | The Journal of biological chemistry 20031107 |
Comparative investigation of superoxide trapping by cyclic nitrone spin traps: the use of singular value decomposition and multiple linear regression analysis. | Free radical biology & medicine 20031101 |
Separation and identification of DMPO adducts of oxygen-centered radicals formed from organic hydroperoxides by HPLC-ESR, ESI-MS and MS/MS. | Journal of the American Society for Mass Spectrometry 20030801 |
EPR spin-trapping evidence for the direct, one-electron reduction of tert-butylhydroperoxide to the tert-butoxyl radical by copper(II): paradigm for a previously overlooked reaction in the initiation of lipid peroxidation. | Journal of the American Chemical Society 20030611 |
Proteasome activation and nNOS down-regulation in neuroblastoma cells expressing a Cu,Zn superoxide dismutase mutant involved in familial ALS. | Journal of neurochemistry 20030601 |
Effect of chlorogenic acid on hydroxyl radical. | Molecular and cellular biochemistry 20030501 |
The metabolism of S-nitrosothiols in the trypanosomatids: the role of ovothiol A and trypanothione. | The Biochemical journal 20030401 |
The plasma superoxide scavenging activity in canine cancer and hepatic disease. | The Journal of veterinary medical science 20030401 |
In vitro genotoxicity of lead acetate: induction of single and double DNA strand breaks and DNA-protein cross-links. | Mutation research 20030303 |
Inhibitory activity of epigallocatechin gallate (EGCg) in paraquat-induced microsomal lipid peroxidation--a mechanism of protective effects of EGCg against paraquat toxicity. | Toxicology 20030201 |
Photochemical and photobiological studies of tirapazamine (SR 4233) and related quinoxaline 1,4-Di-N-oxide analogues. | Chemical research in toxicology 20030201 |
Reduction of nitroxides and radioprotective ability in glioblastoma cells. | Brain tumor pathology 20030101 |
Evaluation of the antioxidant activity of new carotenoid-like compounds by electron paramagnetic resonance. | Drugs under experimental and clinical research 20030101 |
DNA damage induced by methylated trivalent arsenicals is mediated by reactive oxygen species. | Chemical research in toxicology 20021201 |
Antioxidants inhibit endothelin-1 (1-31)-induced proliferation of vascular smooth muscle cells via the inhibition of mitogen-activated protein (MAP) kinase and activator protein-1 (AP-1). | Biochemical pharmacology 20021115 |
Site of methylguanidine production and factors that influence production levels. | Nephron 20021001 |
Inactivation of the 2-oxo acid dehydrogenase complexes upon generation of intrinsic radical species. | European journal of biochemistry 20021001 |
Immunological identification of the heart myoglobin radical formed by hydrogen peroxide. | Free radical biology & medicine 20020801 |
Production of hydroxyl free radical in the xanthine oxidase system with addition of 1-methyl-3-nitro-1-nitrosoguanidine. | Free radical research 20020601 |
Electron paramagnetic resonance spin trapping investigation into the kinetics of glutathione oxidation by the superoxide radical: re-evaluation of the rate constant. | Free radical biology & medicine 20020515 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Hydroxyl radical scavenging action of capsaicin. | Redox report : communications in free radical research 20020101 |
EPR detection of glutathionyl and protein-tyrosyl radicals during the interaction of peroxynitrite with macrophages (J774). | The Journal of biological chemistry 20011026 |
A novel method of measuring hydroxyl radical-scavenging activity of antioxidants using gamma-irradiation. | Free radical research 20010901 |
Reaction of human myoglobin and peroxynitrite: characterizing biomarkers for myoglobin-derived oxidative stress. | Biochemical and biophysical research communications 20010817 |
Enhanced free radical scavenging and decreased lipid peroxidation in the rat fetal brain after treatment with ethyl docosahexaenoate. | Biochimica et biophysica acta 20010629 |
Nitration and oxidation of a hydrophobic tyrosine probe by peroxynitrite in membranes: comparison with nitration and oxidation of tyrosine by peroxynitrite in aqueous solution. | Biochemistry 20010626 |
The role of the DMPO-hydrated electron spin adduct in DMPO-*OH spin trapping. | Free radical biology & medicine 20010615 |
Light-dependent generation of reactive oxygen species in cell culture media. | Free radical biology & medicine 20010615 |
NMR spin trapping: detection of free radical reactions with a new fluorinated DMPO analog. | Free radical biology & medicine 20010515 |
Reaction of human myoglobin and H2O2. Electron transfer between tyrosine 103 phenoxyl radical and cysteine 110 yields a protein-thiyl radical. | The Journal of biological chemistry 20010511 |
Spin trapping of polyunsaturated fatty acid-derived peroxyl radicals: reassignment to alkoxyl radical adducts. | Free radical biology & medicine 20010115 |
Detection of free radicals in skin: a review of the literature and new developments. | Current problems in dermatology 20010101 |
Electron paramagnetic resonance detection of free radicals in UV-irradiated human and mouse skin. | Current problems in dermatology 20010101 |
Bicarbonate enhances nitration and oxidation reactions in biological systems--role of reactive oxygen and nitrogen species. | Advances in experimental medicine and biology 20010101 |
Chalcones: structural requirements for antioxidant, estrogenic and antiproliferative activities. | Anticancer research 20010101 |
Induction of superoxide dismutase and cytotoxicity by manganese in human breast cancer cells. | Archives of biochemistry and biophysics 19990515 |
Determination of the mechanism of free radical generation in human aortic endothelial cells exposed to anoxia and reoxygenation. | The Journal of biological chemistry 19940930 |
Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance. | Arzneimittel-Forschung 19930301 |
Protective effects of spin-trapping agents on adriamycin-induced cardiotoxicity in isolated rat atria. | Free radical research communications 19910101 |
Mechanism of peroxidative activation of the bladder carcinogen 2-amino-4-(5-nitro-2-furyl)-thiazole (ANFT): comparison with benzidine. | Carcinogenesis 19901101 |
Synthesis of spin traps specific for hydroxyl radical. | Journal of medicinal chemistry 19880201 |