2-(3-Methoxy-4-nitrophenyl)-4h-chromen-4-one
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The highly bioactive molecule and signal substance 6-formylindolo[3,2-b]carbazole (FICZ) plays bi-functional roles in cell growth and apoptosis in vitro. | Archives of toxicology 20171001 |
Aryl hydrocarbon receptor signaling modifies Toll-like receptor-regulated responses in human dendritic cells. | Archives of toxicology 20170501 |
Environmental pollutants parathion, paraquat and bisphenol A show distinct effects towards nuclear receptors-mediated induction of xenobiotics-metabolizing cytochromes P450 in human hepatocytes. | Toxicology letters 20151001 |
Activation of the aryl hydrocarbon receptor by the widely used Src family kinase inhibitor 4-amino-5-(4-chlorophenyl)-7-(dimethylethyl)pyrazolo[3,4-d]pyrimidine (PP2). | Archives of toxicology 20150801 |
Aryl hydrocarbon receptor-dependent cell cycle arrest in isolated mouse oval cells. | Toxicology letters 20131023 |
Long interspersed element-1 is differentially regulated by food-borne carcinogens via the aryl hydrocarbon receptor. | Oncogene 20131010 |
Regulation of estrogen sulfotransferase expression by confluence of MCF10A breast epithelial cells: role of the aryl hydrocarbon receptor. | The Journal of pharmacology and experimental therapeutics 20111101 |
Suppression of WIF-1 through promoter hypermethylation causes accelerated proliferation of the aryl hydrocarbon receptor (AHR) overexpressing MCF10AT1 breast cancer cells. | Toxicology 20110729 |
Identification of a high-affinity ligand that exhibits complete aryl hydrocarbon receptor antagonism. | The Journal of pharmacology and experimental therapeutics 20110701 |
Activation of aryl hydrocarbon receptor induces vascular inflammation and promotes atherosclerosis in apolipoprotein E-/- mice. | Arteriosclerosis, thrombosis, and vascular biology 20110601 |
FRET analysis of protein tyrosine kinase c-Src activation mediated via aryl hydrocarbon receptor. | Biochimica et biophysica acta 20110401 |
The AhR is constitutively activated and affects granulosa cell features in the human cell line KGN. | Molecular human reproduction 20110201 |
Species-specific differential AhR expression protects human neural progenitor cells against developmental neurotoxicity of PAHs. | Environmental health perspectives 20101101 |
CH223191 is a ligand-selective antagonist of the Ah (Dioxin) receptor. | Toxicological sciences : an official journal of the Society of Toxicology 20101001 |
Cytochrome P450 1A1 gene regulation by UVB involves crosstalk between the aryl hydrocarbon receptor and nuclear factor kappaB. | Chemico-biological interactions 20100330 |
Arylhydrocarbon receptor activation in NCI-H441 cells and C57BL/6 mice: possible mechanisms for lung dysfunction. | American journal of respiratory cell and molecular biology 20100201 |
TCDD-induced cyclooxygenase-2 expression is mediated by the nongenomic pathway in mouse MMDD1 macula densa cells and kidneys. | Biochemical pharmacology 20100201 |
Antagonism of aryl hydrocarbon receptor signaling by 6,2',4'-trimethoxyflavone. | The Journal of pharmacology and experimental therapeutics 20100101 |
Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators. | Molecular endocrinology (Baltimore, Md.) 20100101 |
The arylhydrocarbon receptor is only marginally involved in the antileukemic effects of its ligand curcumin. | Anticancer research 20091101 |
The conversion of rapid TCCD nongenomic signals to persistent inflammatory effects via select protein kinases in MCF10A cells. | Molecular endocrinology (Baltimore, Md.) 20090401 |
Characterization of MCF mammary epithelial cells overexpressing the Arylhydrocarbon receptor (AhR). | BMC cancer 20090101 |
Significance of the nongenomic, inflammatory pathway in mediating the toxic action of TCDD to induce rapid and long-term cellular responses in 3T3-L1 adipocytes. | Biochemistry 20081230 |
Aryl hydrocarbon receptor signaling mediates expression of indoleamine 2,3-dioxygenase. | Biochemical and biophysical research communications 20081024 |
Roles of cytosolic phospholipase A2 and Src kinase in the early action of 2,3,7,8-tetrachlorodibenzo-p-dioxin through a nongenomic pathway in MCF10A cells. | Molecular pharmacology 20080701 |
Molecular determinants of species-specific agonist and antagonist activity of a substituted flavone towards the aryl hydrocarbon receptor. | Archives of biochemistry and biophysics 20080415 |
Pathogenesis of aryl hydrocarbon receptor-mediated development of lymphoma is associated with increased cyclooxygenase-2 expression. | The American journal of pathology 20071101 |
Cigarette smoke condensate and dioxin suppress culture shock induced senescence in normal human oral keratinocytes. | Oral oncology 20070801 |
beta-Naphthoflavone and 3'-methoxy-4'-nitroflavone exert ambiguous effects on Ah receptor-dependent cell proliferation and gene expression in rat liver 'stem-like' cells. | Biochemical pharmacology 20070515 |
Identification of kaempferol as an inhibitor of cigarette smoke-induced activation of the aryl hydrocarbon receptor and cell transformation. | Carcinogenesis 20070301 |
Lack of the aryl hydrocarbon receptor leads to impaired activation of AKT/protein kinase B and enhanced sensitivity to apoptosis induced via the intrinsic pathway. | The Journal of pharmacology and experimental therapeutics 20070101 |
Impact of the arylhydrocarbon receptor on eugenol- and isoeugenol-induced cell cycle arrest in human immortalized keratinocytes (HaCaT). | Biological chemistry 20060901 |
Aryl hydrocarbon receptor- and calcium-dependent induction of the chemokine CCL1 by the environmental contaminant benzo[a]pyrene. | The Journal of biological chemistry 20060721 |
Human endothelial progenitors constitute targets for environmental atherogenic polycyclic aromatic hydrocarbons. | Biochemical and biophysical research communications 20060317 |
The ligand status of the aromatic hydrocarbon receptor modulates transcriptional activation of BRCA-1 promoter by estrogen. | Cancer research 20060215 |
The aryl hydrocarbon receptor is a regulator of cigarette smoke induction of the cyclooxygenase and prostaglandin pathways in human lung fibroblasts. | American journal of physiology. Lung cellular and molecular physiology 20050901 |
Human CD34-positive hematopoietic stem cells constitute targets for carcinogenic polycyclic aromatic hydrocarbons. | The Journal of pharmacology and experimental therapeutics 20050801 |
Superinduction of CYP1A1 in MCF10A cultures by cycloheximide, anisomycin, and puromycin: a process independent of effects on protein translation and unrelated to suppression of aryl hydrocarbon receptor proteolysis by the proteasome. | Molecular pharmacology 20041001 |
Dioxin-induced immortalization of normal human keratinocytes and silencing of p53 and p16INK4a. | The Journal of biological chemistry 20040625 |
Presence and functional activity of the aryl hydrocarbon receptor in isolated murine cerebral vascular endothelial cells and astrocytes. | Neurotoxicology 20040601 |
TCDD administration after the pro-adipogenic differentiation stimulus inhibits PPARgamma through a MEK-dependent process but less effectively suppresses adipogenesis. | Toxicology and applied pharmacology 20040401 |
3'-methoxy-4'-nitroflavone, a reported aryl hydrocarbon receptor antagonist, enhances Cyp1a1 transcription by a dioxin responsive element-dependent mechanism. | Archives of biochemistry and biophysics 20030801 |
Species-specific transcriptional activity of synthetic flavonoids in guinea pig and mouse cells as a result of differential activation of the aryl hydrocarbon receptor to interact with dioxin-responsive elements. | Molecular pharmacology 20030401 |
The aryl hydrocarbon receptor antagonist, 3'methoxy-4'nitroflavone, attenuates 2,3,7,8-tetrachlorodibenzo-p-dioxin-dependent regulation of growth factor signaling and apoptosis in the MCF-10A cell line. | Toxicology and applied pharmacology 20030401 |
Involvement of a post-transcriptional mechanism in the inhibition of CYP1A1 expression by resveratrol in breast cancer cells. | Biochemical pharmacology 20011015 |
In vivo antagonism of AhR-mediated gene induction by 3'-methoxy-4'-nitroflavone in TCDD-responsive lacZ mice. | Toxicological sciences : an official journal of the Society of Toxicology 20010601 |
Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene- and cigarette smoke condensate-induced cytogenetic damage in vivo. | Carcinogenesis 20010101 |
Suppression of cell cycle progression by flavonoids: dependence on the aryl hydrocarbon receptor. | Carcinogenesis 19990801 |
Substituted flavones as aryl hydrocarbon (Ah) receptor agonists and antagonists. | Biochemical pharmacology 19960426 |