Detection of Δ4-3-oxo-steroid 5β-reductase deficiency by LC-ESI-MS/MS measurement of urinary bile acids.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120701

[Chemical constituents contained in roots of Pterospermum heterophyllum].

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120701

Intracrine and myotrophic roles of 5α-reductase and androgens: a review.

Medicine and science in sports and exercise 20120501

Expression of 5α-reductase in apocrine carcinoma of the breast and its correlation with clinicopathological aggressiveness.

Histopathology 20120501

A novel 3-hydroxysteroid dehydrogenase that regulates reproductive development and longevity.

PLoS biology 20120401

Liver fluke-induced hepatic oxysterols stimulate DNA damage and apoptosis in cultured human cholangiocytes.

Mutation research 20120301

Biosynthesis of a cholesterol-derived brassinosteroid, 28-norcastasterone, in Arabidopsis thaliana.

Journal of experimental botany 20120301

Olesoxime accelerates myelination and promotes repair in models of demyelination.

Annals of neurology 20120201

[The relationship of serum testosterone and its related index with the metabolism syndrome in women at perimenopausal or postmenopausal periods].

Zhonghua fu chan ke za zhi 20120201

Continuous steroid biotransformations in microchannel reactors.

New biotechnology 20120115

Activation mobilizes the cholesterol in the late endosomes-lysosomes of Niemann Pick type C cells.

PloS one 20120101

Cholesterol-lowering probiotics as potential biotherapeutics for metabolic diseases.

Experimental diabetes research 20120101

Inhibition of the Mitochondrial Permeability Transition for Cytoprotection: Direct versus Indirect Mechanisms.

Biochemistry research international 20120101

Influence of pioglitazone on experimental heart failure and hyperlipidemia in rats.

Indian journal of pharmacology 20120101

Steady-state pharmacokinetics of oral testosterone undecanoate with concomitant inhibition of 5α-reductase by finasteride.

International journal of andrology 20111201

Overexpression of hepatic 5α-reductase and 11β-hydroxysteroid dehydrogenase type 1 in visceral adipose tissue is associated with hyperinsulinemia in morbidly obese patients.

Metabolism: clinical and experimental 20111201

New ester derivatives of dehydroepiandrosterone as 5α-reductase inhibitors.

Steroids 20111101

Inhibition of 5α-reductase activity in late pregnancy decreases gestational length and fecundity and impairs object memory and central progestogen milieu of juvenile rat offspring.

Journal of neuroendocrinology 20111101

17α-Estradiol and genistein inhibit high fat diet induced prostate gene expression and prostate growth in the rat.

The Journal of urology 20111001

Potential prostate cancer drug target: bioactivation of androstanediol by conversion to dihydrotestosterone.

Clinical cancer research : an official journal of the American Association for Cancer Research 20110915

Reduced levels of 5-α reductase 2 in adult prostate tissue and implications for BPH therapy.

The Prostate 20110901

Restoration of IFNγR subunit assembly, IFNγ signaling and parasite clearance in Leishmania donovani infected macrophages: role of membrane cholesterol.

PLoS pathogens 20110901

High-resolution phenotypic profiling defines genes essential for mycobacterial growth and cholesterol catabolism.

PLoS pathogens 20110901

Increased muscular dehydroepiandrosterone levels are associated with improved hyperglycemia in obese rats.

American journal of physiology. Endocrinology and metabolism 20110801

Association of genetic variants in the two isoforms of 5α-reductase, SRD5A1 and SRD5A2, in lean patients with polycystic ovary syndrome.

European journal of obstetrics, gynecology, and reproductive biology 20110801

[Active ingredients of Plastrum Testudinis inhibit epidermal stem cell apoptosis in serum-deprived culture].

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20110801

Changes in the activity of connective tissue matrix enzymes in the metabolic syndrome.

Archives of medical science : AMS 20110801

Isolation rearing-induced reduction of brain 5α-reductase expression: relevance to dopaminergic impairments.

Neuropharmacology 20110601

Profiling sterols in cerebrotendinous xanthomatosis: utility of Girard derivatization and high resolution exact mass LC-ESI-MS(n) analysis.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110515

The first successful paternity through in vitro fertilization-intracytoplasmic sperm injection with a man homozygous for the 5α-reductase-2 gene mutation.

Fertility and sterility 20110501

Initial step in the catabolism of cholesterol by Mycobacterium smegmatis mc2 155.

Environmental microbiology 20110401

Impact of 5α-reductase inhibitors on men followed by active surveillance for prostate cancer.

European urology 20110401

Testosterone, not 5α-dihydrotestosterone, stimulates LRH-1 leading to FSH-independent expression of Cyp19 and P450scc in granulosa cells.

Molecular endocrinology (Baltimore, Md.) 20110401

The use of 5α-reductase inhibitors for the prevention and treatment of prostate cancer.

European urology 20110401

[Sterols of marine bryozoan Bugula neritina from the South China Sea].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20110201

The mitochondrial permeability transition pore regulates nitric oxide-mediated apoptosis of neurons induced by target deprivation.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20110105

The role of non-aromatizable testosterone metabolite in metabolic pathways.

Physiological research 20110101

Estrogen and androgen signaling in the pathogenesis of BPH.

Nature reviews. Urology 20110101

Mechanisms of oxysterol-induced carcinogenesis.

Lipids in health and disease 20110101

Impacts of membrane biophysics in Alzheimer's disease: from amyloid precursor protein processing to aβ Peptide-induced membrane changes.

International journal of Alzheimer's disease 20110101

Androgens and estrogens in benign prostatic hyperplasia: past, present and future.

Differentiation; research in biological diversity 20110101

QSAR studies on human 5alpha-reductase inhibitors: unsaturated 3-carboxysteroids.

Acta poloniae pharmaceutica 20110101

Bioactivities from marine algae of the genus Gracilaria.

International journal of molecular sciences 20110101

Caveolin-1-mediated apolipoprotein A-I membrane binding sites are not required for cholesterol efflux.

PloS one 20110101

Hypolipidemic and Antiobesity-Like Activity of Standardised Extract of Hypericum perforatum L. in Rats.

ISRN pharmacology 20110101

Androgen regulation of 5α-reductase isoenzymes in prostate cancer: implications for prostate cancer prevention.

PloS one 20110101

Structural and biochemical characterization of Mycobacterium tuberculosis CYP142: evidence for multiple cholesterol 27-hydroxylase activities in a human pathogen.

The Journal of biological chemistry 20101203

Antimicrobial, antitumor and 5α-reductase inhibitor activities of some hydrazonoyl substituted pyrimidinones.

European journal of medicinal chemistry 20101201

Structure and biological evaluation of novel cytotoxic sterol glycosides from the marine red alga Peyssonnelia sp.

Bioorganic & medicinal chemistry 20101201

Functional redundancy of steroid C26-monooxygenase activity in Mycobacterium tuberculosis revealed by biochemical and genetic analyses.

The Journal of biological chemistry 20101119

Microbial side-chain degradation of ergosterol and its 3-substituted derivatives: a new route for obtaining of deltanoids.

Steroids 20101001

Inhibition of 5alpha-reductase enhances testosterone-induced expression of U19/Eaf2 tumor suppressor during the regrowth of LNCaP xenograft tumor in nude mice.

The Prostate 20101001

Palmitoylation of human FasL modulates its cell death-inducing function.

Cell death & disease 20101001

Olesoxime prevents microtubule-targeting drug neurotoxicity: selective preservation of EB comets in differentiated neuronal cells.

Biochemical pharmacology 20100915

Artifactual measurement of low serum HDL-cholesterol due to paraproteinemia.

Clinical research in cardiology : official journal of the German Cardiac Society 20100901

A study of gender outcome of Egyptian patients with 46,XY disorder of sex development.

Sexual development : genetics, molecular biology, evolution, endocrinology, embryology, and pathology of sex determination and differentiation 20100901

Establishment of a novel model for studying the effects of extracts of Chinese herb medicine on human type II 5alpha-reductase in vitro.

Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20100901

Mycobacterium tuberculosis CYP125A1, a steroid C27 monooxygenase that detoxifies intracellularly generated cholest-4-en-3-one.

Molecular microbiology 20100801

Olesoxime, a cholesterol-like neuroprotectant for the potential treatment of amyotrophic lateral sclerosis.

IDrugs : the investigational drugs journal 20100801

Consequences of switching 5alpha-reductase inhibitors on prostate specific antigen velocity.

The Journal of urology 20100701

The use of 5-alpha reductase inhibitors for the prevention of prostate cancer.

Cancer biology & therapy 20100701

Enzyme-linked immunosorbent assays for doping control of 5alpha-reductase inhibitors finasteride and dutasteride.

Analytica chimica acta 20100625

[Hormones and hair growth].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20100601

Current role for combination therapy in male LUTS.

Archivos espanoles de urologia 20100601

5alpha-reductase inhibitory components as antiandrogens from herbal medicine.

Journal of acupuncture and meridian studies 20100601

Increased atherosclerosis and vascular inflammation in APP transgenic mice with apolipoprotein E deficiency.

Atherosclerosis 20100501

Androgen receptor and 5alpha-reductase immunohistochemical profiles in extramammary Paget disease.

The British journal of dermatology 20100501

Do 5-alpha reductase inhibitors influence the severity of brain injury in men after a stroke?

Medical hypotheses 20100501

Investigating contamination of phytotherapy products for benign prostatic hyperplasia with alpha-blockers and 5alpha-reductase inhibitors.

The Journal of urology 20100501

Effect of the dual 5alpha-reductase inhibitor, dutasteride, on serum testosterone and body mass index in men with benign prostatic hyperplasia.

BJU international 20100401

Testosterone selectively affects aromatase and 5alpha-reductase activities in the green anole lizard brain.

General and comparative endocrinology 20100301

Testosterone metabolites differentially maintain adult morphology in a sexually dimorphic neuromuscular system.

Developmental neurobiology 20100301

Korean urologist's view of practice patterns in diagnosis and management of benign prostatic hyperplasia: a nationwide survey.

Yonsei medical journal 20100301

11β-Hydroxysteroid dehydrogenase type-2 and type-1 (11β-HSD2 and 11β-HSD1) and 5β-reductase activities in the pathogenia of essential hypertension.

Endocrine 20100201

3D-QSAR studies on unsaturated 4-azasteroids as human 5alpha-reductase inhibitors: a self organizing molecular field analysis approach.

European journal of medicinal chemistry 20100201

Current status of 5alpha-reductase inhibitors in the management of lower urinary tract symptoms and BPH.

World journal of urology 20100201

NX-1207: a novel investigational drug for the treatment of benign prostatic hyperplasia.

Expert opinion on investigational drugs 20100201

Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-alpha-reductase inhibitor: a treatment strategy for acne.

The Journal of dermatology 20100201

Does the combination of an alpha1-adrenergic antagonist with a 5alpha-reductase inhibitor improve urinary symptoms more than either monotherapy?

Current opinion in urology 20100101

Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors.

Urologia internationalis 20100101

Production of recombinant cholesterol oxidase containing covalently bound FAD in Escherichia coli.

BMC biotechnology 20100101

Cholesterol-lowering effects of probiotics and prebiotics: a review of in vivo and in vitro findings.

International journal of molecular sciences 20100101

Aromatase and 5-alpha reductase gene expression: modulation by pain and morphine treatment in male rats.

Molecular pain 20100101

Mycobacterial cytochrome p450 125 (cyp125) catalyzes the terminal hydroxylation of c27 steroids.

The Journal of biological chemistry 20091218

Olesoxime (cholest-4-en-3-one, oxime): analgesic and neuroprotective effects in a rat model of painful peripheral neuropathy produced by the chemotherapeutic agent, paclitaxel.

Pain 20091215

Increased androgen receptor and remodeling in the prostatic stroma after the inhibition of 5-alpha reductase and aromatase in gerbil ventral prostate.

Microscopy research and technique 20091201

Effects of the 5 alpha-reductase inhibitor dutasteride on gene expression in prostate cancer xenografts.

The Prostate 20091201

Cholesterol oxidase: biotechnological applications.

The FEBS journal 20091201

Cytochrome P450 125 (CYP125) catalyses C26-hydroxylation to initiate sterol side-chain degradation in Rhodococcus jostii RHA1.

Molecular microbiology 20091201

Inhibiting lateral domain formation in lipid bilayers: simulations of alternative steroid headgroup chemistries.

Journal of the American Chemical Society 20091118

Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research 20091115

Estrogen increases latencies to seizures and levels of 5alpha-pregnan-3alpha-ol-20-one in hippocampus of wild-type, but not 5alpha-reductase knockout, mice.

Epilepsy & behavior : E&B 20091101

Role of neurosteroids in regulating cell death and proliferation in the late gestation fetal brain.

Neuroscience 20091020

Guideline for 5-alpha-reductase inhibitors in the prevention of prostate cancer is premature.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091020

Novel C-6 substituted and unsubstituted pregnane derivatives as 5alpha-reductase inhibitors and their effect on hamster flank organs diameter size.

Steroids 20091001

High abundance of testosterone and salivary androgen-binding protein in the lateral nasal gland of male mice.

The Journal of steroid biochemistry and molecular biology 20091001

Oral cholic acid for hereditary defects of primary bile acid synthesis: a safe and effective long-term therapy.

Gastroenterology 20091001

[Green light laser efficacy in patients with prostatic hyperplasia treatment with 5-alpha reductase inhibitors].

Actas urologicas espanolas 20091001

Intracrine androgenic apparatus in human bone marrow stromal cells.

Journal of cellular and molecular medicine 20090901

A comparison of the packing behavior of egg phosphatidylcholine with cholesterol and biogenically related sterols in Langmuir monolayer films.

Chemistry and physics of lipids 20090901

Increased 5 alpha-reductase activity and adrenocortical drive in women with polycystic ovary syndrome.

The Journal of clinical endocrinology and metabolism 20090901

Cholesterol-rich fluid membranes solubilize ceramide domains: implications for the structure and dynamics of mammalian intracellular and plasma membranes.

The Journal of biological chemistry 20090821

Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat Part 2: Effects on reproductive parameters, on sex behavior, on memory retention and on hypothalamic expression of aromatase and 5alpha-reductases in the offspring.

Toxicology and applied pharmacology 20090815

Caveolin-1-dependent and -independent membrane domains.

Journal of lipid research 20090801

Pharmacological options for treatment of hyperandrogenic disorders.

Mini reviews in medicinal chemistry 20090801

Enduring effects of severe developmental adversity, including nutritional deprivation, on cortisol metabolism in aging Holocaust survivors.

Journal of psychiatric research 20090601

SRD5B1 gene analysis needed for the accurate diagnosis of primary 3-oxo-Delta4-steroid 5beta-reductase deficiency.

Journal of gastroenterology and hepatology 20090501

Chemoprevention of prostate cancer: what can be recommended to patients?

Current urology reports 20090501

Efficient biotransformations using Escherichia coli with tolC acrAB mutations expressing cytochrome P450 genes.

Bioscience, biotechnology, and biochemistry 20090423

Effect of discontinuation of 5alpha-reductase inhibitors on prostate volume and symptoms in men with BPH: a prospective study.

Urology 20090401

Use of 5alpha-reductase inhibitors for prostate cancer chemoprevention: American Society of Clinical Oncology/American Urological Association 2008 Clinical Practice Guideline.

The Journal of urology 20090401

A guideline for discussion and some thoughts.

The Journal of urology 20090401

The urinary steroid profile in patients diagnosed with adrenal incidentaloma.

Clinical biochemistry 20090401

Prostate cancer: a serious disease suitable for prevention.

BJU international 20090401

Anti-androgenic activity of fatty acids.

Chemistry & biodiversity 20090401

Isolation and pharmacological characterization of fatty acids from saw palmetto extract.

Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20090401

Aromatase and 5alpha-reductase inhibition during an exogenous testosterone clamp unveils selective sex steroid modulation of somatostatin and growth hormone secretagogue actions in healthy older men.

The Journal of clinical endocrinology and metabolism 20090301

Can dutasteride delay or prevent the progression of prostate cancer in patients with biochemical failure after radical therapy? Rationale and design of the Avodart after Radical Therapy for Prostate Cancer Study.

BJU international 20090301

Bioconversion of norethisterone, a progesterone receptor agonist into estrogen receptor agonists in osteoblastic cells.

The Journal of endocrinology 20090201

Faecal steroid excretion in humans is affected by calcium supplementation and shows gender-specific differences.

European journal of nutrition 20090201

The limited role of midnight salivary cortisol levels in the diagnosis of subclinical hypercortisolism in patients with adrenal incidentaloma.

European journal of endocrinology 20090101

Anabolic applications of androgens for functional limitations associated with aging and chronic illness.

Frontiers of hormone research 20090101

The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism.

Nuclear receptor signaling 20090101

Therapeutic effects of add-on botulinum toxin A on patients with large benign prostatic hyperplasia and unsatisfactory response to combined medical therapy.

Scandinavian journal of urology and nephrology 20090101

Combination therapy with dutasteride and tamsulosin for the treatment of symptomatic enlarged prostate.

Clinical interventions in aging 20090101

GABA(A) receptor function and gene expression during pregnancy and postpartum.

International review of neurobiology 20090101

Evaluation of 5-alpha reductase activity on cultured fibroblast in patients with hyperandrogenemia.

Romanian journal of internal medicine = Revue roumaine de medecine interne 20090101

The hypocholesterolemic effects of Cistanche tubulosa extract, a Chinese traditional crude medicine, in mice.

The American journal of Chinese medicine 20090101

Current and emerging treatments for amyotrophic lateral sclerosis.

Neuropsychiatric disease and treatment 20090101

Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity.

Diabetes 20081001

Decline of plasma 5alpha-dihydrotestosterone (DHT) levels upon testosterone administration to elderly men with subnormal plasma testosterone and high DHT levels.

Andrologia 20081001

Expression of E-SOD, GPX5 mRNAs and immunoexpression of Cu/ZnSOD in epididymal epithelial cells of finasteride-treated rats.

Andrologia 20081001

Synthesis, characterization and in vitro antibacterial activity of new steroidal 5-en-3-oxazolo and thiazoloquinoxaline.

European journal of medicinal chemistry 20080901

Differences in testicular development between 5alpha-reductase 2 deficiency and isolated bilateral cryptorchidism.

The Journal of urology 20080901

[Effect of fenghuaqianqingcha on experimentally induced prostatic hyperplasia in mice].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080901

The crystal structure of human Delta4-3-ketosteroid 5beta-reductase defines the functional role of the residues of the catalytic tetrad in the steroid double bond reduction mechanism.

Biochemistry 20080812

Specific antinociceptive activity of cholest-4-en-3-one, oxime (TRO19622) in experimental models of painful diabetic and chemotherapy-induced neuropathy.

The Journal of pharmacology and experimental therapeutics 20080801

Inhibition of 5alpha-reduced steroid biosynthesis impedes acquisition of ethanol drinking in male C57BL/6J mice.

Alcoholism, clinical and experimental research 20080801

Combination 5-alpha-reductase inhibitors and alpha-blockers for treatment of lower urinary tract symptoms secondary to benign prostatic hyperplasia.

Current urology reports 20080701

Reduced glucocorticoid production rate, decreased 5alpha-reductase activity, and adipose tissue insulin sensitization after weight loss.

Diabetes 20080601

The effect of 5alpha-reductase inhibition with dutasteride and finasteride on bone mineral density, serum lipoproteins, hemoglobin, prostate specific antigen and sexual function in healthy young men.

The Journal of urology 20080601

Open to debate. The Motion: all men over the age of 50 should be encouraged to take a 5alpha-reductase inhibitor to prevent prostate cancer.

European urology 20080501

Different patterns of 5alpha-reductase expression, cellular distribution, and testosterone metabolism in human follicular dermal papilla cells.

Biochemical and biophysical research communications 20080418

Human Delta4-3-oxosteroid 5beta-reductase (AKR1D1) deficiency and steroid metabolism.

Steroids 20080401

Finasteride induces apoptosis via Bcl-2, Bcl-xL, Bax and caspase-3 proteins in LNCaP human prostate cancer cell line.

International journal of oncology 20080401

Current status of 5alpha-reductase inhibitors in the treatment of benign hyperplasia of prostate.

Indian journal of medical sciences 20080401

Anticholinergic therapy for lower urinary tract symptoms associated with benign prostatic hyperplasia.

Pharmacotherapy 20080301

Oxytocin increases 5alpha-reductase activity of human prostate epithelial cells, but not stromal cells.

The Prostate 20080201

Benign prostatic hyperplasia. Part 2--management.

BMJ (Clinical research ed.) 20080126

Androgen receptor and 5alpha-reductase are expressed in pelvic endometriosis.

BJOG : an international journal of obstetrics and gynaecology 20080101

[Alpha blockers and 5-alpha reductase inhibitors].

Pharmazie in unserer Zeit 20080101

Prolonged human chorionic gonadotrophin stimulation as a tool for investigating and managing undescended testes.

Clinical endocrinology 20071201

Decreased efficiency of potassium-titanyl-phosphate laser photoselective vaporization prostatectomy with long-term 5 alpha-reductase inhibition therapy: is it true?

Urology 20071101

[Effect of fatty acids from plastrum testudinis on proliferation of rat bone mesenchymal stem cell].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology 20071101

Editorial comment on: Low-activity V89L variant in SRD5A2 is associated with aggressive prostate cancer risk: an explanation for the adverse effects observed in chemoprevention trials using 5-alpha-reductase inhibitors.

European urology 20071001

Low-activity V89L variant in SRD5A2 is associated with aggressive prostate cancer risk: an explanation for the adverse effects observed in chemoprevention trials using 5-alpha-reductase inhibitors.

European urology 20071001

Editorial comment on: Low-activity V89L variant in SRD5A2 is associated with aggressive prostate cancer risk: an explanation for the adverse effects observed in chemoprevention trials using 5-alpha-reductase inhibitors.

European urology 20071001

Effects of gonadectomy on glucocorticoid metabolism in obese Zucker rats.

Endocrinology 20071001

LUTS treatment: future treatment options.

Neurourology and urodynamics 20071001

Plasma levels of dihydrotestosterone remain in the normal range in men treated with long-acting parenteral testosterone undecanoate.

Andrologia 20071001

Hormonal protection of gender-related peculiarities of testosterone metabolism in the brain of prenatally stressed rats.

Neuro endocrinology letters 20071001

Biocatalytic synthesis of 4-pregnen-20,21-diol-3-one, a selective inhibitor of human 5alpha-reductase type II.

Journal of enzyme inhibition and medicinal chemistry 20071001

Anabolic effects of testosterone are preserved during inhibition of 5alpha-reductase.

American journal of physiology. Endocrinology and metabolism 20070801

Identification and characterization of cholest-4-en-3-one, oxime (TRO19622), a novel drug candidate for amyotrophic lateral sclerosis.

The Journal of pharmacology and experimental therapeutics 20070801

Fetal distribution of 5alpha-reductase 1 and 5alpha-reductase 2, and their input on human prostate development.

The Journal of urology 20070801

Longitudinal analysis of sexual function reported by men in the Prostate Cancer Prevention Trial.

Journal of the National Cancer Institute 20070704

Inhibition of fatty acid synthase activity in prostate cancer cells by dutasteride.

The Prostate 20070701

Optimizing prostate biopsy techniques.

The Journal of urology 20070601

[Studies on chemical constituents of marine bryozoan Bugula neritina L].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20070601

Re: The interpretation of serum prostate specific antigen in men receiving 5alpha-reductase inhibitors: a review and clinical recommendations.

The Journal of urology 20070501

Doping-control analysis of the 5alpha-reductase inhibitor finasteride: determination of its influence on urinary steroid profiles and detection of its major urinary metabolite.

Therapeutic drug monitoring 20070401

Treatment of men with lower urinary tract symptoms and overactive bladder.

JAMA 20070321

Is it necessary to cure prostate cancer when it is possible? (Understanding the role of prostate inflammation resolution to prostate cancer evolution).

Clinical interventions in aging 20070301

Inhibition of 5alpha-reductase activity in SZ95 sebocytes and HaCaT keratinocytes in vitro.

Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20070201

Differential gene expression during development in two oligodendroglial cell lines overexpressing transferrin: a cDNA array analysis.

Developmental neuroscience 20070101

Histopathological changes induced by therapies in the benign prostate and prostate adenocarcinoma.

Histology and histopathology 20070101

Establishment of type II 5alpha-reductase over-expressing cell line as an inhibitor screening model.

The Journal of steroid biochemistry and molecular biology 20070101

[Modern algorithm of examination and treatment of patients with prostatic adenoma].

Urologiia (Moscow, Russia : 1999) 20070101

A decision aid for GPs for the treatment of elderly male patients with lower urinary tract symptoms (LUTS).

Family practice 20061201

Managing enlarged prostate in primary care.

International journal of clinical practice 20061201

Comorbid LUTS and erectile dysfunction: optimizing their management.

Current medical research and opinion 20061201

Structural and kinetic analyses of the H121A mutant of cholesterol oxidase.

The Biochemical journal 20061115

Interaction of the glycoalkaloid tomatine with DMPC and sterol monolayers studied by surface pressure measurements and Brewster angle microscopy.

The journal of physical chemistry. B 20061109

Effects of testosterone on brain mRNA levels of steroid 5alpha-reductase isozymes in early postnatal life of rat.

Neurochemistry international 20061101

The effect of oxysterols, individually and as a representative mixture from food, on in vitro cultured bovine ovarian granulosa cells.

Molecular and cellular biochemistry 20061101

Long-term results of medical treatment in benign prostatic hyperplasia.

Urology 20061101

One new anthraquinone from marine Streptomyces sp. FX-58.

Natural product research 20061101

Steroid structural requirements for interaction of ostreolysin, a lipid-raft binding cytolysin, with lipid monolayers and bilayers.

Biochimica et biophysica acta 20061001

New dimensions in Hirsutism.

Lasers in medical science 20060901

The interpretation of serum prostate specific antigen in men receiving 5alpha-reductase inhibitors: a review and clinical recommendations.

The Journal of urology 20060901

Bone mineral density in the complete androgen insensitivity and 5alpha-reductase-2 deficiency syndromes.

The Journal of clinical endocrinology and metabolism 20060801

New progesterone derivatives as inhibitors of 5alpha-reductase enzyme and prostate cancer cell growth.

Journal of enzyme inhibition and medicinal chemistry 20060801

Re: The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge.

The Journal of urology 20060701

Stress and acid-base balance in chickens.

Poultry science 20060701

[Feminizing syndrome].

Nihon rinsho. Japanese journal of clinical medicine 20060628

[Hermaphroditism].

Nihon rinsho. Japanese journal of clinical medicine 20060628

[Micropenis].

Nihon rinsho. Japanese journal of clinical medicine 20060628

Comparative non-radioactive RT-PCR assay: an approach to study the neurosteroids biosynthetic pathway in humans.

Journal of neuroscience methods 20060615

Effects of the dual 5 alpha-reductase inhibitor dutasteride on apoptosis in primary cultures of prostate cancer epithelial cells and cell lines.

Cancer 20060615

Synthesis of some new testosterone derivatives fused with substituted pyrazoline ring as promising 5alpha-reductase inhibitors.

Acta pharmaceutica (Zagreb, Croatia) 20060601

[Case-control study of the genes of receptors of the androgens of vitamin-D and of 5-alphareductase in a population of Afro-Caribbean population with prostate cancer].

Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20060601

Sigmoid colon vaginoplasty in children.

European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie 20060601

CD39, NTPDase 1, is attached to the plasma membrane by two transmembrane domains. Why?

Purinergic signalling 20060601

Identifying putative contraceptive targets by dissecting signal transduction networks in the epididymis using an in vivo electroporation (electrotransfer) approach.

Molecular and cellular endocrinology 20060516

Actions of 5alpha-reductase inhibitors on the epididymis.

Molecular and cellular endocrinology 20060516

Phase behavior of lipid monolayers containing DPPC and cholesterol analogs.

Biophysical journal 20060501

Clinical usefulness of serum prostate specific antigen for the detection of prostate cancer is preserved in men receiving the dual 5alpha-reductase inhibitor dutasteride.

The Journal of urology 20060501

Oxidation of cholesterol by a biomimetic oxidant, cetyltrimethylammonium dichromate.

The Journal of organic chemistry 20060428

Dutasteride: a dual 5-alpha reductase inhibitor for the treatment of symptomatic benign prostatic hyperplasia.

The Annals of pharmacotherapy 20060401

Effects of male sex hormones on gender identity, sexual behavior, and cognitive function.

Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20060401

Identification of ligands for DAF-12 that govern dauer formation and reproduction in C. elegans.

Cell 20060324

Noninvasive treatment of benign prostatic hyperplasia. Where do we stand in 2005.

Saudi medical journal 20060301

Androgens modulate the inflammatory response during acute wound healing.

Journal of cell science 20060215

Micellar solubilisation of cholesterol is essential for absorption in humans.

Gut 20060201

5alpha-reductase inhibitory effect of triterpenoids isolated from Ganoderma lucidum.

Biological & pharmaceutical bulletin 20060201

[Epidemiology of BPH and medication approaches].

Therapeutische Umschau. Revue therapeutique 20060201

Androgen replacement and/or 5 alpha reductase inhibitors in aging men.

The Canadian journal of urology 20060201

Revaluation of the role of cholesterol in stabilizing rafts implicated in T cell receptor signaling.

Cellular signalling 20060101

Increased serum estrogenic bioactivity in three male newborns with ambiguous genitalia: a potential consequence of prenatal exposure to environmental endocrine disruptors.

Environmental research 20060101

Inhibitors of 5alpha-reductase in the treatment of benign prostatic hyperplasia.

Current pharmaceutical design 20060101

Discovery and clinical development of dutasteride, a potent dual 5alpha-reductase inhibitor.

Current topics in medicinal chemistry 20060101

A new look at the 5alpha-reductase inhibitor finasteride.

CNS drug reviews 20060101

Roles of cholesterol and lipids in the etiopathogenesis of Alzheimer's disease.

Journal of biomedicine & biotechnology 20060101

Treatment of benign prostatic hyperplasia in patients with cardiovascular disease.

Drugs & aging 20060101

[Treatment of prostatic adenoma patients with inhibitor of 5-alpha-reductase of type I and II avodart (dutasteride)].

Urologiia (Moscow, Russia : 1999) 20060101

Localization of 5alpha-reductase in the rat main olfactory bulb.

The Journal of comparative neurology 20051219

Circulating levels of isoflavones and markers of 5alpha-reductase activity are higher in Japanese compared with New Zealand males: what is the role of circulating steroids in prostate disease?

Steroids 20051215

Model studies of cholesterol and ascorbate oxidation by copper complexes: relevance to Alzheimer's disease beta-amyloid metallochemistry.

Journal of inorganic biochemistry 20051201

The effects of 5alpha-reductase inhibitors on the natural history, detection and grading of prostate cancer: current state of knowledge.

The Journal of urology 20051201

Effectiveness of finasteride on patients with male pattern baldness who have different androgen receptor gene polymorphism.

The journal of investigative dermatology. Symposium proceedings 20051201

Sex steroid metabolism in human peripheral blood mononuclear cells changes with aging.

The Journal of clinical endocrinology and metabolism 20051101

Benign prostatic hyperplasia: an insight into current investigational medical therapies.

Expert opinion on investigational drugs 20051101

Effects of prenatal stress on the activity of an enzyme involved in neurosteroid synthesis during the 'critical period' of sexual differentiation of the brain in male rats.

Neuroscience and behavioral physiology 20051101

Five-alpha-reductase expression in benign and malignant urothelium: correlation with disease characteristics and outcome.

Urology 20051101

[Modern pharmacotherapy of benign prostatic hyperplasia].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20051101

Anti-androgenic activities of Ganoderma lucidum.

Journal of ethnopharmacology 20051031

Sterol structure determines miscibility versus melting transitions in lipid vesicles.

Biophysical journal 20050901

Alzheimer disease beta-amyloid activity mimics cholesterol oxidase.

The Journal of clinical investigation 20050901

Increased A-ring reduction of glucocorticoids in obese Zucker rats: effects of insulin sensitization.

Obesity research 20050901

Changes in the expression of genes related to bile acid synthesis and transport by the rat liver during hepatocarcinogenesis.

Clinical science (London, England : 1979) 20050801

5alpha-Reductase activity in Lycopersicon esculentum: cloning and functional characterization of LeDET2 and evidence of the presence of two isoenzymes.

The Journal of steroid biochemistry and molecular biology 20050801

Cholesterol-dependent lipid assemblies regulate the activity of the ecto-nucleotidase CD39.

The Journal of biological chemistry 20050715

Combined inhibition of types I and II 5 alpha-reductase selectively augments the basal (nonpulsatile) mode of testosterone secretion in young men.

The Journal of clinical endocrinology and metabolism 20050701

Dissecting the structural determinants of the stability of cholesterol oxidase containing covalently bound flavin.

The Journal of biological chemistry 20050617

Membrane cholesterol oxidation inhibits ligand binding function of hippocampal serotonin(1A) receptors.

Biochemical and biophysical research communications 20050603

Effects of finasteride on chronic and acute ethanol withdrawal severity in the WSP and WSR selected lines.

Alcoholism, clinical and experimental research 20050601

Chronic prostatitis.

Clinical evidence 20050601

New drugs for the prostate.

Harvard men's health watch 20050601

Transient changes in the expression pattern of key enzymes for bile acid synthesis during rat liver regeneration.

Biochimica et biophysica acta 20050515

The hair growth promoting effect of Asiasari radix extract and its molecular regulation.

Journal of dermatological science 20050501

Effects of 5 alpha reductase inhibitors on androgen-dependent human prostatic carcinoma cells.

Journal of cancer research and clinical oncology 20050401

Treatment of benign prostatic hyperplasia and occurrence of prostatic surgery and acute urinary retention: a population-based cohort study in the Netherlands.

European urology 20050401

An evidence-based approach to understanding the pharmacological class effect in the management of prostatic diseases.

BJU international 20050401

Ontogeny of 3 beta-hydroxysteroid dehydrogenase and 5 alpha-reductase in the frog brain.

Annals of the New York Academy of Sciences 20050401

New 5alpha-reductase inhibitors: in vitro and in vivo effects.

Steroids 20050301

Effect of testosterone and steroids homologues on indolamines and lipid peroxidation in rat brain.

The Journal of steroid biochemistry and molecular biology 20050301

Role of 5a-reductase inhibitors and selective estrogen receptor modulators as potential chemopreventive agents for prostate cancer.

Clinical prostate cancer 20050301

5alpha-reductase in human embryonic kidney cell line HEK293: evidence for type II enzyme expression and activity.

Molecular and cellular biochemistry 20050201

The role of progesterone metabolites in breast cancer: potential for new diagnostics and therapeutics.

The Journal of steroid biochemistry and molecular biology 20050201

Quantitative appreciation of steroidogenic gene expression in mouse tissues: new roles for type 2 5alpha-reductase, 20alpha-hydroxysteroid dehydrogenase and estrogen sulfotransferase.

The Journal of steroid biochemistry and molecular biology 20050201

Inhibition of 5alpha-reductase blocks prostate effects of testosterone without blocking anabolic effects.

American journal of physiology. Endocrinology and metabolism 20050101

Novel male hormonal contraceptive combinations: the hormonal and spermatogenic effects of testosterone and levonorgestrel combined with a 5alpha-reductase inhibitor or gonadotropin-releasing hormone antagonist.

The Journal of clinical endocrinology and metabolism 20050101

[Effect of selective 5alpha-reductase inhibitor or/and testosterone undecanoate on the reproductive function of male rats].

Zhonghua nan ke xue = National journal of andrology 20050101

Recent advances in the chemistry and pharmacological activity of new steroidal antiandrogens and 5 alpha-reductase inhibitors.

Current medicinal chemistry 20050101

[Dutasteride (Avodart): a novel 5-alpha reductase inhibitor for treatment of benign prostate hypertrophy].

Revue medicale de Bruxelles 20050101

Androgenic correlates of genetic variation in the gene encoding 5alpha-reductase type 1.

Journal of human genetics 20050101

Combination therapy for the pharmacological management of benign prostatic hyperplasia: rationale and treatment options.

Drugs & aging 20050101

Oxysterols from human bile induce apoptosis of canine gallbladder epithelial cells in monolayer culture.

American journal of physiology. Gastrointestinal and liver physiology 20041201

Regulation of 5alpha-reductase isoforms by oxytocin in the rat ventral prostate.

Endocrinology 20041201

Proscar and propecia--a therapeutic perspective.

The Journal of clinical endocrinology and metabolism 20041201

[Benign prostatic hyperplasia: CPG, PSA and 5-alpha-reductase inhibitors].

Annales d'urologie 20041201

[Combination therapy in benign prostatic hyperplasia (BPH)].

Annales d'urologie 20041201

[The PCPT study: the viewpoint of an urologist involved].

Annales d'urologie 20041201

[Use of 5-alpha-reductase inhibitors in the prevention of prostate cancer].

Annales d'urologie 20041201

Altered testicular microsomal steroidogenic enzyme activities in rats with lifetime exposure to soy isoflavones.

The Journal of steroid biochemistry and molecular biology 20041201

Increased allopregnanolone levels in the fetal sheep brain following umbilical cord occlusion.

The Journal of physiology 20041015

Novel cationic lipids incorporating an acid-sensitive acylhydrazone linker: synthesis and transfection properties.

Journal of medicinal chemistry 20041007

[The effect of prenatal stress on activity of the neurosteroids synthesis enzyme in the 'critical period' of brain sexual differentiation in male rats].

Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20041001

Evaluation of cell permeation of a potent 5alpha-reductase inhibitor using MALDI-TOF MS.

Journal of enzyme inhibition and medicinal chemistry 20041001

Effect of dehydroepiandrosterone on radioligand binding of [3H]-testosterone by androgen receptors in rat hypothalamus.

Bulletin of experimental biology and medicine 20041001

Pharmacological therapy of benign prostatic hyperplasia/lower urinary tract symptoms: an overview for the practising clinician.

BJU international 20040901

Further insight into the pathomechanism of acne by considering the 5-alpha-reductase inhibitory effect of linoleic acid.

International journal of dermatology 20040901

Theaflavin-3,3'-digallate and penta-O-galloyl-beta-D-glucose inhibit rat liver microsomal 5alpha-reductase activity and the expression of androgen receptor in LNCaP prostate cancer cells.

Carcinogenesis 20040701

Solubilization and solid-state characterization of a poorly soluble 5-alpha reductase inhibitor.

Drug development and industrial pharmacy 20040701

Lycopene and vitamin E interfere with autocrine/paracrine loops in the Dunning prostate cancer model.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040601

Expression of cytochrome P450c17 and other steroid-converting enzymes in the rat kidney throughout the life-span.

The Journal of steroid biochemistry and molecular biology 20040601

5alpha-reduced glucocorticoids, novel endogenous activators of the glucocorticoid receptor.

The Journal of biological chemistry 20040528

The potential role of cyclooxygenase-2 inhibitors and 5alpha-reductase inhibitors in the prevention of urologic conditions.

The Urologic clinics of North America 20040501

Marked suppression of dihydrotestosterone in men with benign prostatic hyperplasia by dutasteride, a dual 5alpha-reductase inhibitor.

The Journal of clinical endocrinology and metabolism 20040501

Progesterone enhances motor, anxiolytic, analgesic, and antidepressive behavior of wild-type mice, but not those deficient in type 1 5 alpha-reductase.

Brain research 20040409

Implementation of the Prostate Cancer Prevention Trial (PCPT).

Controlled clinical trials 20040401

SRD5B1 (AKR1D1) gene analysis in delta(4)-3-oxosteroid 5beta-reductase deficiency: evidence for primary genetic defect.

Journal of hepatology 20040401

Optimising the medical management of benign prostatic hyperplasia.

European urology 20040401

Finasteride in the treatment of alopecia.

Expert opinion on pharmacotherapy 20040401

A systemic type I 5 alpha-reductase inhibitor is ineffective in the treatment of acne vulgaris.

Journal of the American Academy of Dermatology 20040301

An update on the use of 5alpha-reductase inhibitors.

Drugs of today (Barcelona, Spain : 1998) 20040301

The role of pregnane neurosteroids in ethanol withdrawal: behavioral genetic approaches.

Pharmacology & therapeutics 20040201

A current review of medical therapy for benign prostatic hyperplasia.

The Journal of the American Osteopathic Association 20040201

Cholesterol oxidase senses subtle changes in lipid bilayer structure.

Biochemistry 20040127

[Androgenetic alopecia].

Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20040101

Electron ionization mass spectral fragmentation of derivatized 4,5- and 5,6-epoxysterols.

Rapid communications in mass spectrometry : RCM 20040101

5 alpha-reductase and finasteride in pattern alopecia and acne.

Journal of drugs in dermatology : JDD 20040101

Gene expression in prostate cancer cells treated with the dual 5 alpha-reductase inhibitor dutasteride.

Journal of andrology 20040101

Cytogenetics and etiology of ambiguous genitalia in 120 pediatric patients.

Annals of Saudi medicine 20040101

Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in fetal sheep with umbilicoplacental embolization.

Pediatric research 20031201

Inhibition of chemokine receptor function by membrane cholesterol oxidation.

Experimental cell research 20031115

Effects of insulin-like growth factor I on steroidogenic enzyme expression levels in mouse leydig cells.

Endocrinology 20031101

Decreased gene expression of steroid 5 alpha-reductase 2 in human prostate cancer: implications for finasteride therapy of prostate carcinoma.

The Prostate 20031001

Mutations in SRD5B1 (AKR1D1), the gene encoding delta(4)-3-oxosteroid 5beta-reductase, in hepatitis and liver failure in infancy.

Gut 20031001

Origin of oxysterols in hepatic bile of patients with biliary infection.

The American journal of gastroenterology 20031001

Brain aromatase, 5 alpha-reductase, and 5 beta-reductase change seasonally in wild male song sparrows: relationship to aggressive and sexual behavior.

Journal of neurobiology 20030905

Sequential amination/annulation/aromatization reaction of carbonyl compounds and propargylamine: a new one-pot approach to functionalized pyridines.

The Journal of organic chemistry 20030905

Comparative pharmacophore development for inhibitors of human and rat 5-alpha-reductase.

Journal of molecular graphics & modelling 20030901

On the substrate specificity of human CYP27A1: implications for bile acid and cholestanol formation.

Journal of lipid research 20030801

Semiquantitative RT-PCR method coupled to capillary electrophoresis to study 5alpha-reductase mRNA isozymes in rat ventral prostate in different androgen status.

Molecular and cellular biochemistry 20030801

Familial hyperestrogenism in both sexes: clinical, hormonal, and molecular studies of two siblings.

The Journal of clinical endocrinology and metabolism 20030701

Micropenis and the 5alpha-reductase-2 (SRD5A2) gene: mutation and V89L polymorphism analysis in 81 Japanese patients.

The Journal of clinical endocrinology and metabolism 20030701

SRD5A2 gene polymorphisms and the risk of prostate cancer: a meta-analysis.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20030701

New approach to regioselective synthesis: using proteins in vitro as guidance-regioselective reduction of steroids with guidance from bovine serum albumin.

Biotechnology and bioengineering 20030630

Cerium(III) chloride-mediated reactions of sulfonamide dianions.

The Journal of organic chemistry 20030627

Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer.

The Prostate 20030615

Changes in 5alpha-pregnane steroids and neurosteroidogenic enzyme expression in the perinatal sheep.

Pediatric research 20030601

Association of V89L SRD5A2 polymorphism with prostate cancer development in a Japanese population.

The Journal of urology 20030601

Beyond adrenal and ovarian androgen generation: Increased peripheral 5 alpha-reductase activity in women with polycystic ovary syndrome.

The Journal of clinical endocrinology and metabolism 20030601

Use of finasteride in the treatment of men with androgenetic alopecia (male pattern hair loss).

The journal of investigative dermatology. Symposium proceedings 20030601

Molecular analysis of 5alpha-reductase type 2 gene in eight unrelated egyptian children with suspected 5alpha-reductase deficiency: prevalence of the G34R mutation.

Clinical endocrinology 20030501

Re: Hormonal markers and hepatitis B virus-related hepatocellular carcinoma risk: a nested case-control study among men.

Journal of the National Cancer Institute 20030402

Selective reduction of AKR1C2 in prostate cancer and its role in DHT metabolism.

The Prostate 20030301

Activity and expression of progesterone metabolizing 5alpha-reductase, 20alpha-hydroxysteroid oxidoreductase and 3alpha(beta)-hydroxysteroid oxidoreductases in tumorigenic (MCF-7, MDA-MB-231, T-47D) and nontumorigenic (MCF-10A) human breast cancer cells.

BMC cancer 20030101

Kinetic analysis of LDL oxidation in IHD and IHD risk subjects in Indian population.

Indian journal of clinical biochemistry : IJCB 20030101

Virion-associated cholesterol is critical for the maintenance of HIV-1 structure and infectivity.

AIDS (London, England) 20021122

5 alpha-reductase-catalyzed conversion of testosterone to dihydrotestosterone is increased in prostatic adenocarcinoma cells: suppression by 15-lipoxygenase metabolites of gamma-linolenic and eicosapentaenoic acids.

The Journal of steroid biochemistry and molecular biology 20021101

[Enzyme inhibition in the drug therapy of benign prostatic hyperplasia].

Casopis lekaru ceskych 20021011

5 alpha-reductase and 11 beta-hydroxysteroid dehydrogenase activity in prepubertal Hispanic girls with premature adrenarche.

The Journal of clinical endocrinology and metabolism 20021001

Impact of constitutional genetic variation in androgen/oestrogen-regulating genes on age-related changes in human prostate.

European journal of endocrinology 20021001

Inhibition of type 1 and type 2 5alpha-reductase activity by free fatty acids, active ingredients of Permixon.

The Journal of steroid biochemistry and molecular biology 20021001

Polymorphisms in the androgen receptor and type II 5 alpha-reductase genes and prostate cancer prognosis.

The Prostate 20020901

5Alpha-reductase type 2 genes in Japanese males do not appear to be associated with cryptorchidism.

Fertility and sterility 20020801

Hormonal therapies in acne.

Expert opinion on pharmacotherapy 20020701

Association of polymorphisms within androgen receptor, 5alpha-reductase, and PSA genes with prostate volume, clinical parameters, and endocrine status in elderly men.

The Prostate 20020701

Cholesterol is essential for macrophage inflammatory protein 1 beta binding and conformational integrity of CC chemokine receptor 5.

Blood 20020615

Construction of a catalytically inactive cholesterol oxidase mutant: investigation of the interplay between active site-residues glutamate 361 and histidine 447.

Archives of biochemistry and biophysics 20020615

Induction of apoptosis in rat ventral prostate by finasteride is associated with alteration in MAP kinase pathways and Bcl-2 related family of proteins.

International journal of oncology 20020601

Determination of total cholesterol in serum by cholesterol esterase and cholesterol oxidase immobilized and co-immobilized on to arylamine glass.

Biotechnology and applied biochemistry 20020601

Mutation screening for the 5alpha-reductase type 2 gene in Japanese men with idiopathic azoospermia.

Fertility and sterility 20020501

Safety evaluation of phytosterol esters. Part 7. Assessment of mutagenic activity of phytosterols, phytosterol esters and the cholesterol derivative, 4-cholesten-3-one.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20020401

A simple, accurate, and sensitive assay method of dehydroepiandrosterone sulfate: application for quantitative determination in human breast cyst and duct fluids.

Steroids 20020401

A randomized, double-blind, placebo-controlled trial to determine the effectiveness of botanically derived inhibitors of 5-alpha-reductase in the treatment of androgenetic alopecia.

Journal of alternative and complementary medicine (New York, N.Y.) 20020401

Advances in male contraception.

Expert opinion on investigational drugs 20020301

Anti-androgens for the treatment of hirsutism.

Expert opinion on investigational drugs 20020301

Allelic frequencies of six polymorphic markers for risk of prostate cancer.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20020201

A novel homozygous disruptive mutation in the SRD5A2-gene in a partially virilized patient with 5alpha-reductase deficiency.

International journal of andrology 20020201

Rhodococcus erythropolis ATCC 25544 as a suitable source of cholesterol oxidase: cell-linked and extracellular enzyme synthesis, purification and concentration.

BMC biotechnology 20020101

A49T, V89L and TA repeat polymorphisms of steroid 5alpha-reductase type II and breast cancer risk in Japanese women.

Breast cancer research : BCR 20020101

Molecular quantum similarity-based QSARs for binding affinities of several steroid sets.

Journal of chemical information and computer sciences 20020101

Ethnic differences in the frequency of prostate cancer susceptibility alleles at SRD5A2 and CYP3A4.

Human heredity 20020101

What studies on human longevity tell us about the risk for cancer in the oldest old: data and hypotheses on the genetics and immunology of centenarians.

Experimental gerontology 20020101

Micropenis: an animal model and its human correlates.

Advances in experimental medicine and biology 20020101

The presence of a hydrogen bond between asparagine 485 and the pi system of FAD modulates the redox potential in the reaction catalyzed by cholesterol oxidase.

Biochemistry 20011120

Investigations of cholesterol transformation during sewage treatment: relevance to estrogen formation pathways?

The Science of the total environment 20011112

Biosynthesis of the neurosteroid 3 alpha-hydroxy-4-pregnen-20-one (3 alpha hp), a specific inhibitor of FSH release.

Endocrinology 20011101

Seasonal variation in androgen-metabolizing enzymes in the diencephalon and telencephalon of the male European starling (Sturnus vulgaris).

Journal of neuroendocrinology 20011101

Genetic polymorphisms in the androgen receptor and type II 5 alpha-reductase genes in prostate enlargement.

The Journal of urology 20011001

Polymorphic markers in the SRD5A2 gene and prostate cancer risk: a population-based case-control study.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20011001

Dissection of a flavoenzyme active site: the reaction catalyzed by cholesterol oxidase.

Antioxidants & redox signaling 20011001

Dietary soy-phytoestrogens decrease testosterone levels and prostate weight without altering LH, prostate 5alpha-reductase or testicular steroidogenic acute regulatory peptide levels in adult male Sprague-Dawley rats.

The Journal of endocrinology 20010901

Prostate carcinoma risk and allelic variants of genes involved in androgen biosynthesis and metabolism pathways.

Cancer 20010901

Stable expression of human 5alpha-reductase type II in COS1 cells due to chromosomal gene integration: a novel tool for inhibitor identification.

The Journal of steroid biochemistry and molecular biology 20010901

Bile acids and sterols in urban sewage treatment plants.

Journal of chromatography. A 20010824

Steroid hormone influence on brain calbindin-D(28K) in male prepubertal and ovariectomized rats.

Brain research. Developmental brain research 20010823

Oxygen access to the active site of cholesterol oxidase through a narrow channel is gated by an Arg-Glu pair.

The Journal of biological chemistry 20010810

Divergent immune responses in male and female mice after trauma-hemorrhage: dimorphic alterations in T lymphocyte steroidogenic enzyme activities.

Endocrinology 20010801

Effects of different steroid-biosynthesis inhibitors on the testicular steroidogenesis of the toad Bufo arenarum.

Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20010801

Identification of oxysterols in human bile and pigment gallstones.

Gastroenterology 20010701

5 alpha-reductase type 2 is constitutively expressed in the dermal papilla and connective tissue sheath of the hair follicle in vivo but not during culture in vitro.

The Journal of clinical endocrinology and metabolism 20010601

Steroids in the nervous system: a Pandora's box?

Trends in neurosciences 20010601

Activation of the hypothalamic-pituitary-adrenal axis in obesity: cause or consequence?

Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society 20010601

Sebocytes are the key regulators of androgen homeostasis in human skin.

The Journal of investigative dermatology 20010501

Lifestyle determinants of 5alpha-reductase metabolites in older African-American, white, and Asian-American men.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010501

Solid-state photodimerization of cholest-4-en-3-one.

The Journal of organic chemistry 20010323

Genomic organization of a human 5beta-reductase and its pseudogene and substrate selectivity of the expressed enzyme.

Biochimica et biophysica acta 20010126

V89L polymorphism of type-2, 5-alpha reductase enzyme gene predicts prostate cancer presence and progression.

Urology 20010101

Basic Science.

Urology 20010101

Stable expression of the human 5alpha-reductase isoenzymes type I and type II in HEK293 cells to identify dual and selective inhibitors.

Journal of enzyme inhibition 20010101

QSARs for 6-azasteroids as inhibitors of human type 1 5alpha-reductase: prediction of binding affinity and selectivity relative to 3-BHSD.

Journal of chemical information and computer sciences 20010101