1-(3-chlorophenyl)piperazine
Title | Journal |
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The role of 5-HT(2c) receptor on corticosterone-mediated food intake. | Journal of biochemical and molecular toxicology 20170601 |
Structure-dependent inhibition of the human α1β2γ2 GABAA receptor by piperazine derivatives: A novel mode of action. | Neurotoxicology 20151201 |
BF-1--a novel selective 5-HT2B receptor antagonist blocking neurogenic dural plasma protein extravasation in guinea pigs. | European journal of pharmacology 20150315 |
5-HT2C receptor desensitization moderates anxiety in 5-HTT deficient mice: from behavioral to cellular evidence. | The international journal of neuropsychopharmacology 20150201 |
Additive inhibition of human α1β2γ2 GABAA receptors by mixtures of commonly used drugs of abuse. | Neurotoxicology 20130301 |
Activation of 5-HT(2C) receptors in the dorsal periaqueductal gray increases antinociception in mice exposed to the elevated plus-maze. | Behavioural brain research 20121101 |
Binding of the amphetamine-like 1-phenyl-piperazine to monoamine transporters. | ACS chemical neuroscience 20120919 |
A double dissociation in the effects of 5-HT2A and 5-HT2C receptors on the acquisition and expression of conditioned defeat in Syrian hamsters. | Behavioral neuroscience 20120801 |
Investigations on the 1-(2-biphenyl)piperazine motif: identification of new potent and selective ligands for the serotonin(7) (5-HT(7)) receptor with agonist or antagonist action in vitro or ex vivo. | Journal of medicinal chemistry 20120726 |
Serotonin 5-HT2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons. | American journal of physiology. Endocrinology and metabolism 20120601 |
Piperazine compounds as drugs of abuse. | Drug and alcohol dependence 20120501 |
Effects of serotonin 2C receptor agonists on the behavioral and neurochemical effects of cocaine in squirrel monkeys. | The Journal of pharmacology and experimental therapeutics 20120501 |
Linking the pharmacological content of ecstasy tablets to the subjective experiences of drug users. | Psychopharmacology 20120401 |
Determination of piperazine-type stimulants in human urine by means of microextraction in packed sorbent and high performance liquid chromatography-diode array detection. | Journal of pharmaceutical and biomedical analysis 20120305 |
Methamphetamine, amphetamine, MDMA ('ecstasy'), MDA and mCPP modulate electrical and cholinergic input in PC12 cells. | Neurotoxicology 20120301 |
Influence of serotonergic 5-HT2C receptor antagonist mesulergine in the reversal of memory deficits induced by mCPP. | Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20120201 |
Rapid determination of piperazine-type stimulants in human urine by microextraction in packed sorbent after method optimization using a multivariate approach. | Journal of chromatography. A 20120127 |
Estradiol increases the anorexia associated with increased 5-HT(2C) receptor activation in ovariectomized rats. | Physiology & behavior 20120118 |
Effects of acute tryptophan depletion on prefrontal-amygdala connectivity while viewing facial signals of aggression. | Biological psychiatry 20120101 |
Imbalanced Dopaminergic Transmission Mediated by Serotonergic Neurons in L-DOPA-Induced Dyskinesia. | Parkinson's disease 20120101 |
Yohimbine-induced amygdala activation in pathological gamblers: a pilot study. | PloS one 20120101 |
[Behavioral effects of ketanserine in prenatally stressed female rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20120101 |
Dynamic 5-HT2C receptor editing in a mouse model of obesity. | PloS one 20120101 |
Modulation of human GABAA receptor function: a novel mode of action of drugs of abuse. | Neurotoxicology 20111201 |
Safety, tolerability, and pharmacokinetics of once-daily trazodone extended-release caplets in healthy subjects. | International journal of clinical pharmacology and therapeutics 20111201 |
Differences in serotonin receptor expression in the brainstem may explain the differential ability of a serotonin agonist to block seizure-induced sudden death in DBA/2 vs. DBA/1 mice. | Brain research 20111018 |
Unique brain areas associated with abstinence control are damaged in multiply detoxified alcoholics. | Biological psychiatry 20110915 |
Mirtazapine antagonises the subjective, hormonal and neuronal effects of m-chlorophenylpiperazine (mCPP) infusion: a pharmacological-challenge fMRI (phMRI) study. | NeuroImage 20110915 |
Control of hippocampal theta rhythm by serotonin: role of 5-HT2c receptors. | Neuropharmacology 20110901 |
Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels. | Neuron 20110811 |
Desorption atmospheric pressure photoionization-mass spectrometry in routine analysis of confiscated drugs. | Forensic science international 20110715 |
Chemical profile of meta-chlorophenylpiperazine (m-CPP) in ecstasy tablets by easy ambient sonic-spray ionization, X-ray fluorescence, ion mobility mass spectrometry and NMR. | Analytical and bioanalytical chemistry 20110701 |
Hypophagic and hypolocomotive effects of metachloro phenyl piperazine in rats treated with theophylline and caffeine. | Pakistan journal of pharmaceutical sciences 20110701 |
The trazodone metabolite meta-chlorophenylpiperazine can cause false-positive urine amphetamine immunoassay results. | Journal of analytical toxicology 20110701 |
3,4-methylenedioxymethamphetamine (MDMA) interacts with therapeutic drugs on CYP3A by inhibition of pregnane X receptor (PXR) activation and catalytic enzyme inhibition. | Toxicology letters 20110530 |
Participation of cyclooxygenase pathway in the vasoconstriction induced by 5-HT in the in situ autoperfused kidney of long-term diabetic rats. | European journal of pharmacology 20110520 |
Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110501 |
The autonomic stress-induced hyperthermia response is not enhanced by several anxiogenic drugs. | Physiology & behavior 20110110 |
Separation of positional CPP isomers by chiral HPLC-DAD of seized tablets. | International journal of legal medicine 20110101 |
Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice. | BMC pharmacology 20110101 |
[Effects of 5-HT1 and 5-HT2 serotonin receptors on anxiety- and depression-like behavior in female rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
Development of a rapid LC-MS/MS method for direct urinalysis of designer drugs. | Drug testing and analysis 20110101 |
Influence of early stress on social abilities and serotonergic functions across generations in mice. | PloS one 20110101 |
[Influence of 2-ethyl-6-methyl-3-hydroxypyridine hemisuccinate on cerebral blood perfusion in rats under experimental pathology conditions]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
[Cerebrovascular and antiserotoninergic activity of the combination of tropoxin and mexidol]. | Eksperimental'naia i klinicheskaia farmakologiia 20110101 |
Acute and chronic treatment with serotonin reuptake inhibitors exert opposite effects on respiration in rats: possible implications for panic disorder. | Journal of psychopharmacology (Oxford, England) 20101201 |
Dose proportionality of once-daily trazodone extended-release caplets under fasting conditions. | Journal of clinical pharmacology 20101201 |
5-HT2CRs expressed by pro-opiomelanocortin neurons regulate insulin sensitivity in liver. | Nature neuroscience 20101201 |
Blockade of 5-HT2A/2C-type receptors impairs learning in female rats in the course of estrous cycle. | Bulletin of experimental biology and medicine 20101201 |
Neuro-psychopharmacogenetics and Neurological Antecedents of Posttraumatic Stress Disorder: Unlocking the Mysteries of Resilience and Vulnerability. | Current neuropharmacology 20101201 |
Constitutive activity of serotonin 2C receptors at G protein-independent signaling: modulation by RNA editing and antidepressants. | Molecular pharmacology 20101101 |
Trazodone, meta-chlorophenylpiperazine (an hallucinogenic drug and trazodone metabolite), and the hallucinogen trifluoromethylphenylpiperazine cross-react with the EMIT®II ecstasy immunoassay in urine. | Journal of analytical toxicology 20101101 |
[Behavioral effects of m-CPP and ketanserine during ovarian cycle in female rats]. | Eksperimental'naia i klinicheskaia farmakologiia 20101101 |
Hypothalamic orexin and pro-opiomelanocortin activities are essential for the anorexic effects of m-chlorophenylpiperazine in mice. | The international journal of neuropsychopharmacology 20101001 |
Multiple anxiogenic drugs recruit a parvalbumin-containing subpopulation of GABAergic interneurons in the basolateral amygdala. | Progress in neuro-psychopharmacology & biological psychiatry 20101001 |
5-HT2C receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatment. | Journal of neurochemistry 20101001 |
Analysis of phenylpiperazine-like stimulants in human hair as trimethylsilyl derivatives by gas chromatography-mass spectrometry. | Journal of chromatography. A 20101001 |
Detection of 1-benzylpiperazine, 1-(3-trifluoromethylphenyl)-piperazine, and 1-(3-chlorophenyl)-piperazine in 3,4-methylenedioxymethamphetamine-positive urine samples. | Journal of analytical toxicology 20101001 |
mCPP: an undesired addition to the ecstasy market. | Journal of psychopharmacology (Oxford, England) 20100901 |
[Effect of tropoxin on cerebrovascular effects of meta-chlorophenylpiperazine and serotonin]. | Eksperimental'naia i klinicheskaia farmakologiia 20100901 |
Abstracts of the 5(th) Cachexia Conference, Barcelona, Spain, December 5-8, 2009. | Journal of cachexia, sarcopenia and muscle 20100901 |
Determining the subjective effects of TFMPP in human males. | Psychopharmacology 20100801 |
Fear-potentiated startle, but not light-enhanced startle, is enhanced by anxiogenic drugs. | Pharmacology, biochemistry, and behavior 20100701 |
Tolerance to 3,4-methylenedioxymethamphetamine is associated with impaired serotonin release. | Addiction biology 20100701 |
Comprehensive identification of active compounds in tablets by flow-injection data-dependent tandem mass spectrometry combined with library search. | Forensic science international 20100415 |
Rikkunshito and 5-HT2C receptor antagonist improve cisplatin-induced anorexia via hypothalamic ghrelin interaction. | Regulatory peptides 20100409 |
Utility of multivariate analysis in support of in vitro metabolite identification studies: retrospective analysis using the antidepressant drug nefazodone. | Xenobiotica; the fate of foreign compounds in biological systems 20100401 |
Acute SSRI-induced anxiogenic and brain metabolic effects are attenuated 6 months after initial MDMA-induced depletion. | Behavioural brain research 20100305 |
The effects of the 5-HT2C agonist m-chlorophenylpiperazine on elite athletes with unexplained underperformance syndrome (overtraining). | British journal of sports medicine 20100301 |
Acquisition session length modulates consolidation effects produced by 5-HT2C ligands in a mouse autoshaping-operant procedure. | Behavioural pharmacology 20100301 |
Neuronal correlates and serotonergic modulation of behavioural inhibition and reward in healthy and antisocial individuals. | Journal of psychiatric research 20100201 |
5-hydroxytryptamine receptor stimulation of mitochondrial biogenesis. | The Journal of pharmacology and experimental therapeutics 20100201 |
Tricyclic dihydroquinazolinones as novel 5-HT2C selective and orally efficacious anti-obesity agents. | Bioorganic & medicinal chemistry letters 20100201 |
A novel 5-HT(2A) receptor antagonist exhibits antidepressant-like effects in a battery of rodent behavioural assays: approaching early-onset antidepressants. | Pharmacology, biochemistry, and behavior 20100101 |
Decreased response inhibition in middle-aged male patients with type 2 diabetes. | BioPsychoSocial medicine 20100101 |
Cobalamin deficiency, hyperhomocysteinemia, and dementia. | Neuropsychiatric disease and treatment 20100101 |
Brain serotonin synthesis in adult males characterized by physical aggression during childhood: a 21-year longitudinal study. | PloS one 20100101 |
Revisiting the role of neurons in neurovascular coupling. | Frontiers in neuroenergetics 20100101 |
Tinnitus psychopharmacology: A comprehensive review of its pathomechanisms and management. | Neuropsychiatric disease and treatment 20100101 |
The many faces of trichotillomania. | International journal of trichology 20100101 |
An overview of Indian research in obsessive compulsive disorder. | Indian journal of psychiatry 20100101 |
Content of ecstasy in the Netherlands: 1993-2008. | Addiction (Abingdon, England) 20091201 |
Further pharmacological characterization of 5-HT(2C) receptor agonist-induced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus in vivo. | British journal of pharmacology 20091101 |
Characterization of the contractile 5-hydroxytryptamine receptor in the autoperfused kidney of L-NAME hypertensive rats. | European journal of pharmacology 20091012 |
Physical binding pocket induction for affinity prediction. | Journal of medicinal chemistry 20091008 |
Role of spinal serotonergic pathways in sneeze-induced urethral continence reflex in rats. | American journal of physiology. Renal physiology 20091001 |
Design and synthesis of pyridazinone-based 5-HT(2C) agonists. | Bioorganic & medicinal chemistry letters 20091001 |
Characterizing the effects of 5-HT(2C) receptor ligands on motor activity and feeding behaviour in 5-HT(2C) receptor knockout mice. | Neuropharmacology 20090901 |
Discovery of a novel azepine series of potent and selective 5-HT2C agonists as potential treatments for urinary incontinence. | Bioorganic & medicinal chemistry letters 20090901 |
Serotonin 5-HT2C receptor-independent expression of hypothalamic NOR1, a novel modulator of food intake and energy balance, in mice. | Biochemical and biophysical research communications 20090821 |
Individual differences in the sensitivity to serotonergic drugs: a pharmacobehavioural approach using rats selected on the basis of their response to novelty. | Psychopharmacology 20090801 |
Overexpression of 5-HT2C receptors in forebrain leads to elevated anxiety and hypoactivity. | The European journal of neuroscience 20090701 |
Fluvoxamine exerts anorexic effect in 5-HT2C receptor mutant mice with heterozygous mutation of beta-endorphin gene. | The international journal of neuropsychopharmacology 20090501 |
Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin. | Biological psychiatry 20090501 |
1-(m-Chlorophenyl)piperazine induces depressogenic-like behaviour in rodents by stimulating the neuronal 5-HT(2A) receptors: proposal of a modified rodent antidepressant assay. | European journal of pharmacology 20090417 |
Synergistic actions of apomorphine and m-chlorophenylpiperazine on ejaculation, but not penile erection in rats. | Biomedical research (Tokyo, Japan) 20090401 |
Behavioral and neurochemical profile of m-CPP following exposure to single restraint stress in rat. | Acta neurologica Belgica 20090301 |
Subthalamic neurons show increased firing to 5-HT2C receptor activation in 6-hydroxydopamine-lesioned rats. | Brain research 20090223 |
Creation and application of psychoactive designer drugs data library using liquid chromatography with photodiode array spectrophotometry detector and gas chromatography-mass spectrometry. | Talanta 20090215 |
Prevalence of ergot derivatives in natural ryegrass pastures: detection and pathogenicity in the horse. | Theriogenology 20090201 |
Distribution and neurochemical characterization of neurons within the nucleus of the solitary tract responsive to serotonin agonist-induced hypophagia. | Behavioural brain research 20090103 |
Trazodone generates m-CPP: in 2008 risks from m-CPP might outweigh benefits of trazodone. | The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101 |
Obsessive-compulsive disorder and related disorders: a comprehensive survey. | Annals of general psychiatry 20090101 |
Effect of buspirone on thermal sensory and pain thresholds in human volunteers. | BMC clinical pharmacology 20090101 |
Analysis of host-mediated repair mechanisms after human CNS-stem cell transplantation for spinal cord injury: correlation of engraftment with recovery. | PloS one 20090101 |
Migraine: an overview. | The open neurology journal 20090101 |
Anti-inflammatory effects of m-chlorophenylpiperazine in brain glia cells. | International immunopharmacology 20081210 |
5-HT2CRs expressed by pro-opiomelanocortin neurons regulate energy homeostasis. | Neuron 20081126 |
Dopaminergic modulation of auditory cortex-dependent memory consolidation through mTOR. | Cerebral cortex (New York, N.Y. : 1991) 20081101 |
Dopaminergic and serotonergic modulation of persistent behaviour in the reinforced spatial alternation model of obsessive-compulsive disorder. | Psychopharmacology 20081101 |
Relationship of the serotonin transporter with prolactin response to meta-chlorophenylpiperazine in cocaine dependence. | Journal of psychiatric research 20081001 |
Characterization of contractile 5-hydroxytryptamine receptor subtypes in the in situ autoperfused kidney in the anaesthetized rat. | European journal of pharmacology 20080911 |
Effects of chemotherapeutic agents 5-fluorouracil and methotrexate alone and combined in a mouse model of learning and memory. | Psychopharmacology 20080901 |
Hypersensitivity of 5-HT2 receptors in OCD patients. An increased prolactin response after a challenge with meta-chlorophenylpiperazine and pre-treatment with ritanserin and placebo. | Journal of psychiatric research 20080901 |
Taste-dependent sociophobia: when food and company do not mix. | Behavioural brain research 20080822 |
HPLC analysis of the antidepressant trazodone and its main metabolite m-CPP in human plasma. | Journal of pharmaceutical and biomedical analysis 20080805 |
High throughput and sensitive determination of trazodone and its primary metabolite, m-chlorophenylpiperazine, in human plasma by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080801 |
Exercise is associated with reduction in the anxiogenic effect of mCPP on acoustic startle. | Behavioral neuroscience 20080801 |
5-HT(2C) receptor activation is a common mechanism on proerectile effects of apomorphine, oxytocin and melanotan-II in rats. | European journal of pharmacology 20080728 |
Serotonin systems upregulate the expression of hypothalamic NUCB2 via 5-HT2C receptors and induce anorexia via a leptin-independent pathway in mice. | Biochemical and biophysical research communications 20080718 |
Behavioral effects of 1-(m-chlorophenyl)piperazine (m-CPP) in a rat model of tardive dyskinesia. | Pakistan journal of pharmaceutical sciences 20080701 |
Liquid chromatography-atmospheric pressure ionization electrospray mass spectrometry determination of 'hallucinogenic designer drugs' in urine of consumers. | Journal of pharmaceutical and biomedical analysis 20080609 |
Antagonism of AMPA receptors produces anxiolytic-like behavior in rodents: effects of GYKI 52466 and its novel analogues. | Psychopharmacology 20080601 |
5HT2 receptor activation facilitates P2X receptor mediated excitatory neurotransmission to cardiac vagal neurons in the nucleus ambiguus. | Neuropharmacology 20080601 |
Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism. | Gastroenterology 20080601 |
Acute chlorophenylpiperazine overdose: a case report and review of the literature. | Therapeutic drug monitoring 20080601 |
Detection of novel reactive metabolites of trazodone: evidence for CYP2D6-mediated bioactivation of m-chlorophenylpiperazine. | Drug metabolism and disposition: the biological fate of chemicals 20080501 |
Effects of a Cannabinoid1 receptor antagonist and Serotonin2C receptor agonist alone and in combination on motivation for palatable food: a dose-addition analysis study in mice. | The Journal of pharmacology and experimental therapeutics 20080501 |
Behavioral characterization of serotonergic activation in the flatworm Planaria. | Behavioural pharmacology 20080501 |
m-CPP induced hypolocomotion does not interfere in the assessment of memory functions in rats. | Pakistan journal of pharmaceutical sciences 20080401 |
Inverse agonist and neutral antagonist actions of antidepressants at recombinant and native 5-hydroxytryptamine2C receptors: differential modulation of cell surface expression and signal transduction. | Molecular pharmacology 20080301 |
Single-blind and Double-blind Randomized Controlled Trials of Palmtherapy(R), an Alternative Medical Approach, for Anxiety before Cardiac Catheterization. | Evidence-based complementary and alternative medicine : eCAM 20080301 |
Investigation of the first deaths in the United Kingdom involving the detection and quantitation of the piperazines BZP and 3-TFMPP. | Journal of analytical toxicology 20080301 |
Stereotypic behaviour in the deer mouse: pharmacological validation and relevance for obsessive compulsive disorder. | Progress in neuro-psychopharmacology & biological psychiatry 20080215 |
5-HT2 receptor activation in the midbrain periaqueductal grey (PAG) reduces anxiety-like behaviour in mice. | Behavioural brain research 20080211 |
Ejaculatory response induced by a 5-HT2 receptor agonist m-CPP in rats: differential roles of 5-HT2 receptor subtypes. | Pharmacology, biochemistry, and behavior 20080201 |
Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity. | Journal of medicinal chemistry 20080124 |
5-HT(2C) antagonism blocks blood oxygen level-dependent pharmacological-challenge magnetic resonance imaging signal in rat brain areas related to feeding. | The European journal of neuroscience 20080101 |
Comparison of electron and chemical ionization modes by validation of a quantitative gas chromatographic-mass spectrometric assay of new generation antidepressants and their active metabolites in plasma. | Journal of chromatography. A 20071228 |
An antidepressant that extends lifespan in adult Caenorhabditis elegans. | Nature 20071122 |
Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways. | Cell metabolism 20071107 |
MDMA-like behavioral effects of N-substituted piperazines in the mouse. | Pharmacology, biochemistry, and behavior 20071101 |
Fluvoxamine, a selective serotonin reuptake inhibitor, and 5-HT2C receptor inactivation induce appetite-suppressing effects in mice via 5-HT1B receptors. | The international journal of neuropsychopharmacology 20071001 |
Behavioural effects of rapid intravenous administration of meta-chlorophenylpiperazine (m-CPP) in patients with generalized social anxiety disorder, panic disorder and healthy controls. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20071001 |
Adrenergic and serotoninergic regulation of myocardial contractility in patients with various morphofunctional changes in the heart resulting from chronic heart failure. | Bulletin of experimental biology and medicine 20071001 |
Increase of plasma brain-derived neurotrophic factor levels in two psychotic depressed patients responding to lithium addition to paroxetine treatment. | Neuropsychiatric disease and treatment 20071001 |
Stimulation of growth hormone release by 5-hydroxytryptamine (5-HT) in cultured rat anterior pituitary cell aggregates: evidence for mediation by 5-HT2B, 5-HT7, 5-HT1B, and ketanserin-sensitive receptors. | Endocrinology 20070901 |
The chronobiology and neurobiology of winter seasonal affective disorder. | Dialogues in clinical neuroscience 20070901 |
Proof of a 1-(3-chlorophenyl)piperazine (mCPP) intake: use as adulterant of cocaine resulting in drug-drug interactions? | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070815 |
Trazodone inhibits T-type calcium channels. | Neuropharmacology 20070801 |
Possible involvement of spinal noradrenergic mechanisms in the antiallodynic effect of intrathecally administered 5-HT2C receptor agonists in the rats with peripheral nerve injury. | European journal of pharmacology 20070712 |
Amygdala-prefrontal disconnection in borderline personality disorder. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070701 |
Neurochemical and behavioral effects of m-CPP in a rat model of tardive dyskinesia. | Pakistan journal of pharmaceutical sciences 20070701 |
5-HT2 modulation of AY-9944 induced atypical absence seizures. | Neuroscience letters 20070511 |
Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior. | Neuroscience 20070511 |
Novel class of arylpiperazines containing N-acylated amino acids: their synthesis, 5-HT1A, 5-HT2A receptor affinity, and in vivo pharmacological evaluation. | Bioorganic & medicinal chemistry 20070415 |
High-throughput quantitation of nefazodone and its metabolites in human plasma by high flow direct-injection LC-MS/MS. | Journal of pharmaceutical and biomedical analysis 20070411 |
Role of pregabalin in the treatment of generalized anxiety disorder. | Neuropsychiatric disease and treatment 20070401 |
The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain. | European journal of pharmacology 20070322 |
Discovery of (R)-9-ethyl-1,3,4,10b-tetrahydro-7-trifluoromethylpyrazino[2,1-a]isoindol- 6(2H)-one, a selective, orally active agonist of the 5-HT(2C) receptor. | Journal of medicinal chemistry 20070322 |
Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze. | Behavioural brain research 20070312 |
5-Hydroxytryptamine2C receptor contribution to m-chlorophenylpiperazine and N-methyl-beta-carboline-3-carboxamide-induced anxiety-like behavior and limbic brain activation. | The Journal of pharmacology and experimental therapeutics 20070301 |
Effect of meta-chlorophenylpiperazine and cholecystokinin on food intake of Osborne-Mendel and S5B/P1 rats. | Obesity (Silver Spring, Md.) 20070301 |
Selective activation of 5-HT(2C) receptors stimulates GABA-ergic function in the rat substantia nigra pars reticulata: a combined in vivo electrophysiological and neurochemical study. | Neuroscience 20070223 |
Influence of diltiazem on the behavior of zolpidem-treated mice in the elevated-plus maze test. | Journal of neural transmission (Vienna, Austria : 1996) 20070201 |
Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity. | Neurotoxicity research 20070201 |
3,4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings. | Psychopharmacology 20070101 |
Carbon dioxide inhalation induces dose-dependent and age-related negative affectivity. | PloS one 20070101 |
Salicylate-induced tinnitus: molecular mechanisms and modulation by anxiety. | Progress in brain research 20070101 |
Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010: a comparison with diazepam and buspirone. | European journal of pharmacology 20061228 |
Hyperphagia alters expression of hypothalamic 5-HT2C and 5-HT1B receptor genes and plasma des-acyl ghrelin levels in Ay mice. | Endocrinology 20061201 |
Serotonin dysfunction in pathological gamblers: increased prolactin response to oral m-CPP versus placebo. | CNS spectrums 20061201 |
Polymorphism in the serotonin transporter gene and moderators of prolactin response to meta-chlorophenylpiperazine in African-American cocaine abusers and controls. | Psychiatry research 20061115 |
[Role of the serotonergic nervous system in anxiety disorders and the anxiolytic mechanism of selective serotonin reuptake inhibitors]. | Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20061101 |
Role of the 5-HT2C receptor in improving weight-supported stepping in adult rats spinalized as neonates. | Brain research 20060927 |
The genetic studies of obsessive-compulsive disorder and its future directions. | Yonsei medical journal 20060831 |
Relationship of prolactin response to meta-chlorophenylpiperazine with severity of drug use in cocaine dependence. | Human psychopharmacology 20060801 |
Functional magnetic resonance imaging and c-Fos mapping in rats following an anorectic dose of m-chlorophenylpiperazine. | NeuroImage 20060701 |
Effects of soybean food pellets on m-CPP-induced anxiety model of mice. | Biological & pharmaceutical bulletin 20060701 |
Pharmacological evidence for a functional serotonin-2B receptor in a human uterine smooth muscle cell line. | The Journal of pharmacology and experimental therapeutics 20060601 |
Pharmacological characterization of 5-hydroxytryptamine-induced contraction in the chicken gastrointestinal tract. | Autonomic & autacoid pharmacology 20060401 |
Pharmacological evaluation of the stress-induced social avoidance model of anxiety. | Brain research bulletin 20060331 |
Childhood sexual abuse in relation to neurobiological challenge tests in patients with borderline personality disorder and normal controls. | Psychiatry research 20060330 |
A negative feedback system between brain serotonin systems and plasma active ghrelin levels in mice. | Biochemical and biophysical research communications 20060317 |
Relationship of disinhibition and aggression to blunted prolactin response to meta-chlorophenylpiperazine in cocaine-dependent patients. | Psychopharmacology 20060301 |
Serotonin 1B and 2C receptor interactions in the modulation of feeding behaviour in the mouse. | Psychopharmacology 20060301 |
5-HT2c receptor activation induces grooming behaviour in rats: possible correlations with obsessive-compulsive disorder. | Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20060301 |
Pyrrolo(iso)quinoline derivatives as 5-HT(2C) receptor agonists. | Bioorganic & medicinal chemistry letters 20060201 |
Does meta-chlorophenylpiperazine (mCPP) activate human platelets? | Platelets 20060201 |
gamma-Aminobutyric acid-serotonin interactions in healthy men: implications for network models of psychosis and dissociation. | Biological psychiatry 20060115 |
Medial parabrachial nucleus neurons modulate d-fenfluramine-induced anorexia through 5HT2C receptors. | Brain research 20060105 |
Desensitization of 5-HT2A receptor function by chronic administration of selective serotonin reuptake inhibitors. | Brain research 20060105 |
Discriminative stimulus effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans trained to discriminate among d-amphetamine, meta-chlorophenylpiperazine and placebo. | Drug and alcohol dependence 20060104 |
Effects of mu-CPP and mesulergine on dietary choices in deprived rats: possible mechanisms of their action. | Progress in neuro-psychopharmacology & biological psychiatry 20060101 |
Pharmacologic analysis of non-synonymous coding h5-HT2A SNPs reveals alterations in atypical antipsychotic and agonist efficacies. | The pharmacogenomics journal 20060101 |
The C(-1019)G 5-HT1A promoter polymorphism and personality traits: no evidence for significant association in alcoholic patients. | Behavioral and brain functions : BBF 20060101 |
[Metachlorophenylpiperazine (mCPP): a new designer drug]. | Therapie 20060101 |
Development of a solid phase extraction for 13 'new' generation antidepressants and their active metabolites for gas chromatographic-mass spectrometric analysis. | Journal of chromatography. A 20051209 |
Estradiol supplementation modulates neuroendocrine response to M-chlorophenylpiperazine in menstrual status migrainosus triggered by oral contraception-free interval. | Human reproduction (Oxford, England) 20051201 |
Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice. | Neuropharmacology 20051201 |
Methylone and mCPP, two new drugs of abuse? | Addiction biology 20051201 |
Ethanol substitutes for the discriminative stimulus effects of m-chlorophenylpiperazine. | Brain research 20051116 |
m-Chlorophenylpiperazine exacerbates perception of salicylate-induced tinnitus in rats. | The European journal of neuroscience 20051101 |
Enhanced 5-HT2C receptor signaling is associated with haloperidol-induced 'early onset' vacuous chewing in rats: implications for antipsychotic drug therapy. | Psychopharmacology 20051001 |
Chronic treatment with duloxetine is necessary for an anxiolytic-like response in the mouse zero maze: the role of the serotonin transporter. | Psychopharmacology 20051001 |
Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat. | Clinical and experimental pharmacology & physiology 20051001 |
Inhibition of serotonin transporters by cocaine and meprylcaine through 5-TH2C receptor stimulation facilitates their seizure activities. | Brain research 20050928 |
Does the panic attack activate the hypothalamic-pituitary-adrenal axis? | Anais da Academia Brasileira de Ciencias 20050901 |
The AGNP-TDM Expert Group Consensus Guidelines: focus on therapeutic monitoring of antidepressants. | Dialogues in clinical neuroscience 20050901 |
Updated overview of the putative role of the serotoninergic system in obsessive-compulsive disorder. | Neuropsychiatric disease and treatment 20050901 |
Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa. | American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20050805 |
Serotonergic/glutamatergic interactions: potentiation of phencyclidine-induced stimulus control by citalopram. | Pharmacology, biochemistry, and behavior 20050701 |
Analgesic therapy in postherpetic neuralgia: a quantitative systematic review. | PLoS medicine 20050701 |
Responsiveness of 5-HT(1A) and 5-HT2 receptors in the rat orbitofrontal cortex after long-term serotonin reuptake inhibition. | Journal of psychiatry & neuroscience : JPN 20050701 |
Brain angiotensin and anxiety-related behavior: the transgenic rat TGR(ASrAOGEN)680. | Brain research 20050607 |
The use of sudden darkness in mice: a behavioural and pharmacological approach. | Psychopharmacology 20050601 |
Metabolism of designer drugs of abuse. | Current drug metabolism 20050601 |
Endophenotypes in the personality disorders. | Dialogues in clinical neuroscience 20050601 |
Effects of 5,7-dihydroxytryptamine lesion of the dorsal raphe nucleus on ethanol discrimination in the rat. | Alcohol (Fayetteville, N.Y.) 20050601 |
Reinforced spatial alternation as an animal model of obsessive-compulsive disorder (OCD): investigation of 5-HT2C and 5-HT1D receptor involvement in OCD pathophysiology. | Biological psychiatry 20050515 |
Trazodone and its active metabolite m-chlorophenylpiperazine as partial agonists at 5-HT1A receptors assessed by [35S]GTPgammaS binding. | Journal of psychopharmacology (Oxford, England) 20050501 |
Effects of serotonin and serotonergic agonists and antagonists on the production of tumor necrosis factor alpha and interleukin-6. | Psychiatry research 20050430 |
Effect of the activation of central 5-HT2C receptors by the 5-HT2C agonist mCPP on blood pressure and heart rate in rats. | Brain research 20050408 |
Measurement and characterization of energy intake in the mouse. | Current protocols in pharmacology 20050401 |
Agonist diversity in 5-HT(2C) receptor-mediated weight control in rats. | Psychopharmacology 20050301 |
m-CPP, a 5-HT2C receptor agonist that modifies the perfusion pressure of the hindquarter vascular bed of anesthetized rat. | Pharmacology 20050201 |
Anxiogenic treatments do not increase fear-potentiated startle in mice. | Biological psychiatry 20050101 |
Serotonergic 5-HT2C receptors as a potential therapeutic target for the design antiepileptic drugs. | Current topics in medicinal chemistry 20050101 |
Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs. | Neuroscience 20050101 |
Pharmacological challenge with a serotonin 1D agonist in alcohol dependence. | BMC psychiatry 20050101 |
Effects of the 5-HT7 receptor antagonists SB-269970 and DR 4004 in autoshaping Pavlovian/instrumental learning task. | Behavioural brain research 20041206 |
Thermogenic effect of YM348, a novel 5-HT2C-receptor agonist, in rats. | The Journal of pharmacy and pharmacology 20041201 |
Anxiety-like state associates with taste to produce conditioned taste aversion. | Biological psychiatry 20041201 |
Behavioral effects of serotonin and serotonin agonists in two crayfish species, Procambarus clarkii and Orconectes rusticus. | Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20041201 |
Behavioral phenotype of pre-proenkephalin-deficient mice on diverse congenic backgrounds. | Psychopharmacology 20041101 |
Neuroimaging and 5-HT2C receptor polymorphism: a HMPAO-SPECT study in healthy male probands using mCPP-challenge of the 5-HT2C receptor. | Pharmacopsychiatry 20041101 |
Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout mice. | Psychopharmacology 20041001 |
Behavioural effects of rapid intravenous administration of meta-chlorophenylpiperazine in patients with panic disorder and controls. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20041001 |
Increased repetitive behaviours and prolactin responsivity to oral m-chlorophenylpiperazine in adults with autism spectrum disorders. | The international journal of neuropsychopharmacology 20040901 |
Differential effects of 5-HT1 and 5-HT2 receptor agonists on hindlimb movements in paraplegic mice. | Progress in neuro-psychopharmacology & biological psychiatry 20040901 |
A 5-HT2C agonist elicits hyperactivity and oral dyskinesia with hypophagia in rabbits. | Physiology & behavior 20040801 |
Chronic treatment with fluvoxamine desensitizes 5-HT2C receptor-mediated hypolocomotion in rats. | Pharmacology, biochemistry, and behavior 20040801 |
Pharmacological characterisation of the agonist radioligand binding site of 5-HT(2A), 5-HT(2B) and 5-HT(2C) receptors. | Naunyn-Schmiedeberg's archives of pharmacology 20040801 |
Pharmacokinetics of m-chlorophenylpiperazine after intravenous and oral administration in healthy male volunteers: implication for the pharmacodynamic profile. | Pharmacopsychiatry 20040701 |
Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats. | Pharmacology 20040601 |
Serotonin function, personality-trait variations, and childhood abuse in women with bulimia-spectrum eating disorders. | The Journal of clinical psychiatry 20040601 |
New arylpiperazine 5-HT(1A) receptor ligands containing the pyrimido[2,1-f]purine fragment: synthesis, in vitro, and in vivo pharmacological evaluation. | Journal of medicinal chemistry 20040506 |
Indoline derivatives as 5-HT(2C) receptor agonists. | Bioorganic & medicinal chemistry letters 20040503 |
mCPP-induced hyperactivity in 5-HT2C receptor mutant mice is mediated by activation of multiple 5-HT receptor subtypes. | Neuropharmacology 20040401 |
Relationship between anorexia and loss of serotonin uptake sites in brain of mice and rats receiving d-norfenfluramine or d-fenfluramine. | Pharmacology, biochemistry, and behavior 20040301 |
The application of the principles of clinical drug development to pharmacological challenge tests of the serotonergic system. | Journal of psychopharmacology (Oxford, England) 20040301 |
Antiallodynic effects of intrathecally administered 5-HT(2C) receptor agonists in rats with nerve injury. | Pain 20040301 |
m-Chlorophenylpiperazine (mCPP) modulates the discriminative stimulus effects of cocaine through actions at the 5-HT2C receptor. | Behavioral neuroscience 20040201 |
Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor. | European journal of pharmacology 20040126 |
Neurobiological correlates of diagnosis and underlying traits in patients with borderline personality disorder compared with normal controls. | Psychiatry research 20040101 |
Modification of human 5-HT(2C) receptor function by Cys23Ser, an abundant, naturally occurring amino-acid substitution. | Molecular psychiatry 20040101 |
Pharmacological profile of YM348, a novel, potent and orally active 5-HT2C receptor agonist. | European journal of pharmacology 20040101 |
Bulimia nervosa with co-morbid avoidant personality disorder: behavioural characteristics and serotonergic function. | Psychological medicine 20040101 |
Serotonergic dissection of obsessive compulsive symptoms: a challenge study with m-chlorophenylpiperazine and sumatriptan. | Neuropsychobiology 20040101 |
Serotoninergics attenuate hyperlocomotor activity in rats. Potential new therapeutic strategy for hyperactivity. | Neurotoxicity research 20040101 |
Substitution profiles of N-methyl-D-aspartate antagonists in ethanol-discriminating inbred mice. | Alcohol (Fayetteville, N.Y.) 20040101 |
5-HT2C receptors inhibit and 5-HT1A receptors activate the generation of spike-wave discharges in a genetic rat model of absence epilepsy. | Experimental neurology 20031201 |
Depression of mGluR-mediated IPSCs by 5-HT in dopamine neurons of the rat substantia nigra pars compacta. | The European journal of neuroscience 20031101 |
Implications of compulsive and impulsive traits for serotonin status in women with bulimia nervosa. | Psychiatry research 20031015 |
A PET study after treatment with an anxiety-provoking agent, m-chlorophenyl-piperazine, in conscious rhesus monkeys. | Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030901 |
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy. | British journal of pharmacology 20030901 |
Involvement of 5-HT(2) receptor in imipramine-induced hyperglycemia in mice. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20030901 |
Central 5-HT2B/2C and 5-HT3 receptor stimulation decreases salt intake in sodium-depleted rats. | Brain research 20030815 |
Regulation of septo-hippocampal activity by 5-hydroxytryptamine(2C) receptors. | The Journal of pharmacology and experimental therapeutics 20030801 |
Discriminative stimulus effects of m-chlorophenylpiperazine as a model of the role of serotonin receptors in anxiety. | Life sciences 20030801 |
MDMA exposure alters cognitive and electrophysiological sensitivity to rapid tryptophan depletion in rhesus monkeys. | Pharmacology, biochemistry, and behavior 20030801 |
Serotonin in the dorsal periaqueductal gray modulates inhibitory avoidance and one-way escape behaviors in the elevated T-maze. | European journal of pharmacology 20030725 |
Higher-end serotonin receptors: 5-HT(5), 5-HT(6), and 5-HT(7). | Journal of medicinal chemistry 20030703 |
Neuroendocrine response to the serotonin agonist M-chlorophenylpiperazine in women with menstrual status migrainosus. | Neuroendocrinology 20030701 |
m-CPP-induced self-grooming is mediated by 5-HT2C receptors. | Behavioural brain research 20030616 |
Effects of single and repeated electroconvulsive shock on the social and agonistic behaviour of resident rats. | Neuropharmacology 20030601 |
Screening for and validated quantification of amphetamines and of amphetamine- and piperazine-derived designer drugs in human blood plasma by gas chromatography/mass spectrometry. | Journal of mass spectrometry : JMS 20030601 |
Oral administration of the 5-HT2Creceptor agonist, mCPP, reduces body weight gain in rats over 28 days as a result of maintained hypophagia. | Psychopharmacology 20030501 |
Experimental anxiety and antiepileptics: the effects of valproate and vigabatrin in the mirrored chamber test. | Methods and findings in experimental and clinical pharmacology 20030501 |
Effects of m-CPP in altering neuronal function: blocking depolarization in invertebrate motor and sensory neurons but exciting rat dorsal horn neurons. | Brain research 20030418 |
Serotonin induces tonic firing in layer V pyramidal neurons of rat prefrontal cortex during postnatal development. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030415 |
Neurogenic dural protein extravasation induced by meta-chlorophenylpiperazine (mCPP) involves nitric oxide and 5-HT2B receptor activation. | Cephalalgia : an international journal of headache 20030301 |
Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT 2C receptor responsivity. | Neuropharmacology 20030301 |
The glycine transporter-1 inhibitors NFPS and Org 24461: a pharmacological study. | Pharmacology, biochemistry, and behavior 20030301 |
Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs. | Biological psychiatry 20030215 |
Differential regulation of somatodendritic and nerve terminal dopamine release by serotonergic innervation of substantia nigra. | Journal of neurochemistry 20030201 |
Effect of repeated administration of dexfenfluramine on feeding and brain Fos in mice. | Physiology & behavior 20030201 |
Central serotonergic effects of m-chlorophenylpiperazine (mCPP) among normal control adolescents. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030101 |
Pharmacological characterization of 5-HT(1B) receptor-mediated inhibition of local excitatory synaptic transmission in the CA1 region of rat hippocampus. | British journal of pharmacology 20030101 |
5-HT1B receptor knockout mice show a compensatory reduction in 5-HT2C receptor function. | The European journal of neuroscience 20030101 |
5-HT2C receptor agonists as potential drugs for the treatment of obesity. | Current topics in medicinal chemistry 20030101 |
Piperazine-derived designer drug 1-(3-chlorophenyl)piperazine (mCPP): GC-MS studies on its metabolism and its toxicological detection in rat urine including analytical differentiation from its precursor drugs trazodone and nefazodone. | Journal of analytical toxicology 20030101 |
Anxiolytic-like profile of propofol, a general anesthetic, in the plus-maze test in mice. | Polish journal of pharmacology 20030101 |
Neuroendocrine response to meta-chlorophenylpiperazine and ipsapirone in relation to anxiety and aggression. | Psychiatry research 20021215 |
Synthesis and pharmacological evaluation of new arylpiperazines. 3-[4-[4-(3-chlorophenyl)-1-piperazinyl]butyl]-quinazolidin-4-one - a dual serotonin 5-HT(1A)/5-HT(2A) receptor ligand with an anxiolytic-like activity. | Bioorganic & medicinal chemistry 20021201 |
Cognitive performance of MDMA-treated rhesus monkeys: sensitivity to serotonergic challenge. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021201 |
Serotonergic dysregulation in bipolar disorders: a literature review of serotonergic challenge studies. | Bipolar disorders 20021201 |
Antidepressants reduce phosphoinositide-specific phospholipase C (PI-PLC) activity and the mRNA and protein expression of selective PLC beta 1 isozyme in rat brain. | Neuropharmacology 20021201 |
Involvement of 5-HT(2A/2B/2C) receptors on memory formation: simple agonism, antagonism, or inverse agonism? | Cellular and molecular neurobiology 20021201 |
Neurogenetics of emotional reactivity to stress in animals. | Dialogues in clinical neuroscience 20021201 |
Sleep-wake effects of meta-chlorophenyl piperazine and mianserin in the behaviorally depressed rat. | European journal of pharmacology 20021122 |
2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine]. | The Journal of pharmacology and experimental therapeutics 20021101 |
5-HT2C receptor mediation of unconditioned escape behaviour in the unstable elevated exposed plus maze. | Psychopharmacology 20021101 |
The effects of gender and gonadal steroids on the neuroendocrine and temperature response to m-chlorophenylpiperazine in leuprolide-induced hypogonadism in women and men. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021101 |
In vitro identification of metabolic pathways and cytochrome P450 enzymes involved in the metabolism of etoperidone. | Xenobiotica; the fate of foreign compounds in biological systems 20021101 |
Allelic variants of the serotonin(2C) receptor and neuroendocrinological responses to the serotonin(2C) receptor agonist m-chlorophenylpiperazine in healthy male volunteers. | Pharmacopsychiatry 20021101 |
Effects of GABA(A) compounds on mCPP drug discrimination in rats. | Life sciences 20021018 |
mCPP-induced hypophagia in rats is unaffected by the profile of dietary unsaturated fatty acids. | Pharmacology, biochemistry, and behavior 20021001 |
p-Methylthioamphetamine and 1-(m-chlorophenyl)piperazine, two non-neurotoxic 5-HT releasers in vivo, differ from neurotoxic amphetamine derivatives in their mode of action at 5-HT nerve endings in vitro. | Journal of neurochemistry 20020901 |
Are there anxious genes? | Dialogues in clinical neuroscience 20020901 |
5-HT(2C) receptor activation by m-chlorophenylpiperazine detected in humans with fMRI. | Neuroreport 20020827 |
Relationship between plasma concentrations of trazodone and its active metabolite, m-chlorophenylpiperazine, and its clinical effect in depressed patients. | Therapeutic drug monitoring 20020801 |
Metachlorophenylpiperazine (m-CPP) induced intracavernous pressure responses in anaesthetized rats. | International journal of impotence research 20020801 |
The effects of serotonin agonists on the hypothalamic regulation of sexual receptivity in Syrian hamsters. | Hormones and behavior 20020801 |
Central administration of mCPP, a serotonin 5-HT(2B/2C) agonist, decreases water intake in rats. | Pharmacology, biochemistry, and behavior 20020701 |
Blunted prefrontal cortical 18fluorodeoxyglucose positron emission tomography response to meta-chlorophenylpiperazine in impulsive aggression. | Archives of general psychiatry 20020701 |
Therapeutic and adverse actions of serotonin transporter substrates. | Pharmacology & therapeutics 20020701 |
Ritanserin antagonism of m-chlorophenylpiperazine effects in neuroleptic-free schizophrenics patients: support for serotonin-2 receptor modulation of schizophrenia symptoms. | Psychopharmacology 20020601 |
Treatment of depression associated with the menstrual cycle: premenstrual dysphoria, postpartum depression, and the perimenopause. | Dialogues in clinical neuroscience 20020601 |
Gonadal steroids, brain, and behavior: role of context. | Dialogues in clinical neuroscience 20020601 |
Ethopharmacological analysis of the unstable elevated exposed plus maze, a novel model of extreme anxiety: predictive validity and sensitivity to anxiogenic agents. | Psychopharmacology 20020501 |
Antinociceptive role of 5-HT1A receptors in rat spinal cord. | British journal of anaesthesia 20020501 |
Altered prolactin response to M-chlorophenylpiperazine in monkeys previously treated with 3,4-methylenedioxymethamphetamine (MDMA) or fenfluramine. | Synapse (New York, N.Y.) 20020401 |
Human CYP3A4 and the metabolism of nefazodone and hydroxynefazodone by human liver microsomes and heterologously expressed enzymes. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020401 |
Serotonin 2C receptor agonists and the behavioural satiety sequence in mice. | Pharmacology, biochemistry, and behavior 20020401 |
Alteration in 5-hydroxytryptamine agonist-induced behaviour following a corticosterone implant in adult rats. | Pharmacology, biochemistry, and behavior 20020401 |
Serotonin releasing agents. Neurochemical, therapeutic and adverse effects. | Pharmacology, biochemistry, and behavior 20020401 |
The nature of the acetylcholine and 5-hydroxytryptamine receptors in buccal smooth muscle of the pest slug Deroceras reticulatum. | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020401 |
Role of 5-hT2C receptors in the hypophagic effect of m-CPP, ORG 37684 and CP-94,253 in the rat. | Progress in neuro-psychopharmacology & biological psychiatry 20020401 |
The atypical 5-HT2 receptor mediating tachycardia in pithed rats: pharmacological correlation with the 5-HT2A receptor subtype. | British journal of pharmacology 20020301 |
Saccadic peak velocity and EEG as end-points for a serotonergic challenge test. | Human psychopharmacology 20020301 |
Comparison of the potency of MDL 100,907 and SB 242084 in blocking the serotonin (5-HT)(2) receptor agonist-induced increases in rat serum corticosterone concentrations: evidence for 5-HT(2A) receptor mediation of the HPA axis. | Neuropharmacology 20020201 |
Effects of fenfluramine, m-CPP and triazolam on repeated-acquisition in squirrel monkeys before and after neurotoxic MDMA administration. | Psychopharmacology 20020201 |
Evaluation of isotryptamine derivatives at 5-HT(2) serotonin receptors. | Bioorganic & medicinal chemistry letters 20020121 |
Perturbations of plasma cortisol and DHEA-S following discontinuation of cocaine use in cocaine addicts. | Psychoneuroendocrinology 20020101 |
Psychomotor slowing, neuroendocrine responses, and behavioral changes after oral administration of meta-chlorophenylpiperazine in normal volunteers. | Psychiatry research 20011231 |
The subjective effects of MDMA and mCPP in moderate MDMA users. | Drug and alcohol dependence 20011201 |
The effect of olanzapine treatment on m-chlorophenylpiperazine-induced hormone release in schizophrenia. | Journal of clinical psychopharmacology 20011201 |
The 5-HT2C/2B receptor agonist m-chlorophenylpiperazine (mCPP) inhibits 2-deoxy-D-glucose (2-DG)-induced hyperphagia in rats. | Biological & pharmaceutical bulletin 20011201 |
Effects of serotonin and serotonin analogs on posture and agonistic behavior in crayfish. | Journal of comparative physiology. A, Sensory, neural, and behavioral physiology 20011201 |
Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635. | The international journal of neuropsychopharmacology 20011201 |
m-CPP hypolocomotion is selectively antagonized by compounds with high affinity for 5-HT(2C) receptors but not 5-HT(2A) or 5-HT(2B) receptors. | Behavioural pharmacology 20011201 |
Evaluation of the absorption, excretion and metabolism of [14C] etoperidone in man. | Xenobiotica; the fate of foreign compounds in biological systems 20011101 |
Altered responsiveness to 5-HT at the crayfish neuromuscular junction due to chronic p-CPA and m-CPP treatment. | Brain research 20011019 |
Association of serotonin and cortisol indices with childhood abuse in bulimia nervosa. | Archives of general psychiatry 20010901 |
Mapping of brain activation in response to pharmacological agents using fMRI in the rat. | Magnetic resonance imaging 20010901 |
Agonist-induced functional desensitization of recombinant human 5-HT2 receptors expressed in CHO-K1 cells. | Biochemical pharmacology 20010815 |
Self-destructiveness and serotonin function in bulimia nervosa. | Psychiatry research 20010805 |
Pedophilia is accompanied by increased plasma concentrations of catecholamines, in particular epinephrine. | Psychiatry research 20010805 |
Tryptophan hydroxylase gene and major psychoses. | Psychiatry research 20010805 |
SB-243213; a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile: lack of tolerance and withdrawal anxiety. | Neuropharmacology 20010801 |
Altered response to meta-chlorophenylpiperazine in anorexia nervosa: support for a persistent alteration of serotonin activity after short-term weight restoration. | The International journal of eating disorders 20010701 |
Effect of a low tryptophan diet on the prolactin responses to the 5-HT2A agonist DOI in the rat. | Pharmacopsychiatry 20010701 |
The serotonergic 5-HT(2C) agonist m-chlorophenylpiperazine increases weight-supported locomotion without development of tolerance in rats with spinal transections. | Experimental neurology 20010601 |
A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long-term defect in thermoregulation. | Psychopharmacology 20010601 |
1-(m-chlorophenyl)piperazine (mCPP) dissociates in vivo serotonin release from long-term serotonin depletion in rat brain. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010501 |
Dissociation of systemic and hippocampal modulation of rat locomotor activity by 5-HT(2C) receptors. | Neuroscience research 20010501 |
Strain-dependent effects of diazepam and the 5-HT2B/2C receptor antagonist SB 206553 in spontaneously hypertensive and Lewis rats tested in the elevated plus-maze. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20010501 |
Decreased tryptophan availability but normal post-synaptic 5-HT2c receptor sensitivity in chronic fatigue syndrome. | Psychological medicine 20010501 |
Effects of genetic polymorphism of CYP1A2 inducibility on the steady-state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazine in depressed Japanese patients. | Pharmacology & toxicology 20010501 |
Effect of aerobic exercise on behavioral and neuroendocrine responses to meta-chlorophenylpiperazine and to ipsapirone in untrained healthy subjects. | Psychopharmacology 20010501 |
Discriminative stimulus properties of indorenate, a 5-HT1A, 5-HT1B and 5-HT2C agonist: a study in rats. | Journal of psychopharmacology (Oxford, England) 20010301 |
Neuroendocrine and behavioral responses to mCPP in Obsessive-Compulsive Disorder. | Psychoneuroendocrinology 20010201 |
Increased m-CPP-induced oral dyskinesia after lesion of serotonergic neurons. | Pharmacology, biochemistry, and behavior 20010201 |
Investigations into migraine pathogenesis: time course for effects of m-CPP, BW723C86 or glyceryl trinitrate on appearance of Fos-like immunoreactivity in rat trigeminal nucleus caudalis (TNC). | Cephalalgia : an international journal of headache 20010201 |
Low versus standard dose mCPP challenge in obsessive-compulsive patients. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010101 |
Lower baseline plasma cortisol and prolactin together with increased body temperature and higher mCPP-induced cortisol responses in men with pedophilia. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010101 |
Implications of impulsive and affective symptoms for serotonin function in bulimia nervosa. | Psychological medicine 20010101 |
Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX1) receptors, with downstream 5-HT2C receptor involvement. | Psychopharmacology 20010101 |
m-Chlorophenylpiperazine excites non-dopaminergic neurons in the rat substantia nigra and ventral tegmental area by activating serotonin-2C receptors. | Neuroscience 20010101 |
Inhibition of K(+)-evoked release of rat striatal 5-hydroxytryptamine by an atypical antidepressant: trazodone. | Neuropsychobiology 20010101 |
Modulation of 5-HT(2A) receptor-mediated head-twitch behaviour in the rat by 5-HT(2C) receptor agonists. | Pharmacology, biochemistry, and behavior 20010101 |
Evidence for possible involvement of 5-HT(2B) receptors in the cardiac valvulopathy associated with fenfluramine and other serotonergic medications. | Circulation 20001205 |
Cloning, expression, and characterization of ferret 5-HT(3) receptor subunit. | European journal of pharmacology 20000707 |
Agonist high and low affinity state ratios predict drug intrinsic activity and a revised ternary complex mechanism at serotonin 5-HT(2A) and 5-HT(2C) receptors. | Synapse (New York, N.Y.) 20000201 |
Serotonin(2C) receptors appear to mediate genetic sensitivity to cocaine-induced convulsions. | Psychopharmacology 19991001 |
Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions. | Psychopharmacology 19990701 |
High-affinity agonist binding correlates with efficacy (intrinsic activity) at the human serotonin 5-HT2A and 5-HT2C receptors: evidence favoring the ternary complex and two-state models of agonist action. | Journal of neurochemistry 19990501 |
Comparisons of hallucinogenic phenylisopropylamine binding affinities at cloned human 5-HT2A, -HT(2B) and 5-HT2C receptors. | Naunyn-Schmiedeberg's archives of pharmacology 19990101 |
Trazodone is metabolized to m-chlorophenylpiperazine by CYP3A4 from human sources. | Drug metabolism and disposition: the biological fate of chemicals 19980601 |
[3H]Rauwolscine: an antagonist radioligand for the cloned human 5-hydroxytryptamine2b (5-HT2B) receptor. | Naunyn-Schmiedeberg's archives of pharmacology 19980101 |
Effect of fenfluramine challenge on cocaine craving in addicted male users. | The American journal on addictions 19980101 |
The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons. | European journal of pharmacology 19970501 |
SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist. | Neuropharmacology 19970101 |
Bupropion plasma levels and CYP2D6 phenotype. | Therapeutic drug monitoring 19961001 |
In vitro and in vivo profile of SB 206553, a potent 5-HT2C/5-HT2B receptor antagonist with anxiolytic-like properties. | British journal of pharmacology 19960201 |
Radiolabelling of the human 5-HT2A receptor with an agonist, a partial agonist and an antagonist: effects on apparent agonist affinities. | Biochemical pharmacology 19960112 |
Post-synaptic 5-HT1A receptor involvement in yawning and penile erections induced by apomorphine, physostigmine and mCPP in rats. | Psychopharmacology 19950801 |
Trazodone treatment increases plasma prolactin concentrations in depressed patients. | International clinical psychopharmacology 19950601 |
Penile erection and yawning induced by 5-HT1C receptor agonists in male rats: relationship with dopaminergic and oxytocinergic transmission. | European journal of pharmacology 19940811 |
Central action of glaucine in rodents. | Acta poloniae pharmaceutica 19940101 |
Prolonged penile erections induced by hydroxyzine: possible mechanism of action. | Neuropsychobiology 19940101 |
d-Fenfluramine- and d-norfenfluramine-induced hypophagia: differential mechanisms and involvement of postsynaptic 5-HT receptors. | European journal of pharmacology 19930921 |
Molecular cloning and expression of a 5-hydroxytryptamine7 serotonin receptor subtype. | The Journal of biological chemistry 19930825 |
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs. | Molecular pharmacology 19930301 |
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor. | Molecular pharmacology 19930301 |
Trazodone induction of migraine headache through mCPP. | The American journal of psychiatry 19920501 |
Basic central pharmacological properties of thiophosphoric acid alkaloid derivatives from Chelidonium majus L. | Polish journal of pharmacology and pharmacy 19920101 |
Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor. | Molecular pharmacology 19910801 |
A pilot placebo-controlled study of chronic m-CPP administration in Alzheimer's disease. | Biological psychiatry 19910715 |
Serotonergic responsivity in obsessive-compulsive disorder. Effects of chronic clomipramine treatment. | Archives of general psychiatry 19880201 |
Central action of ipsapirone, a new anxiolytic drug, on serotoninergic, noradrenergic and dopaminergic functions. | Journal of neural transmission 19870101 |
Central antiserotonergic and antidopaminergic action of pirenperone, a putative 5-HT2 receptor antagonist. | Polish journal of pharmacology and pharmacy 19850101 |
1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole. | The Journal of pharmacy and pharmacology 19821001 |