Butadiene monoxide
Title | Journal |
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Inhibitory potency of 4-carbon alkanes and alkenes toward CYP2E1 activity. | Toxicology 20140406 |
DNA damage induced by three major metabolites of 1,3-butadiene in human hepatocyte L02 cells. | Mutation research 20120918 |
A mechanistic modeling framework for predicting metabolic interactions in complex mixtures. | Environmental health perspectives 20111201 |
Kinetics of ethylene and ethylene oxide in subcellular fractions of lungs and livers of male B6C3F1 mice and male fischer 344 rats and of human livers. | Toxicological sciences : an official journal of the Society of Toxicology 20111001 |
Quantitative analysis of trihydroxybutyl mercapturic acid, a urinary metabolite of 1,3-butadiene, in humans. | Chemical research in toxicology 20110919 |
1,3-Butadiene: Biomarkers and application to risk assessment. | Chemico-biological interactions 20110630 |
Stereoselective coupling reaction of dimethylzinc and alkyne toward nickelacycles. | Organic letters 20110506 |
1,3-Butadiene: II. Genotoxicity profile. | Critical reviews in toxicology 20101001 |
Exposure-response of 1,2:3,4-diepoxybutane-specific N-terminal valine adducts in mice and rats after inhalation exposure to 1,3-butadiene. | Toxicological sciences : an official journal of the Society of Toxicology 20100601 |
Mutagenicity of stereochemical configurations of 1,3-butadiene epoxy metabolites in human cells. | Research report (Health Effects Institute) 20100601 |
Quantitative investigation on the metabolism of 1,3-butadiene and of its oxidized metabolites in once-through perfused livers of mice and rats. | Toxicological sciences : an official journal of the Society of Toxicology 20100301 |
Stereoselective ring expansion of vinyl oxiranes: mechanistic insights and natural product total synthesis. | Angewandte Chemie (International ed. in English) 20100222 |
Cob(I)alamin for trapping butadiene epoxides in metabolism with rat S9 and for determining associated kinetic parameters. | Chemical research in toxicology 20090901 |
Genotoxicity of 1,3-butadiene and its epoxy intermediates. | Research report (Health Effects Institute) 20090801 |
Investigation on the mechanisms of genotoxicity of butadiene, styrene and their combination in human lymphocytes using the Comet assay. | Mutation research 20090512 |
Alternative reagents for chemical noise reduction in liquid chromatography-mass spectrometry using selective ion-molecule reactions. | Journal of the American Society for Mass Spectrometry 20090101 |
An efficient and general enantioselective synthesis of sphingosine, phythosphingosine, and 4-substituted derivatives. | Organic letters 20090101 |
Evaluation of cancer tests of 1,3-butadiene using internal dose, genotoxic potency, and a multiplicative risk model. | Cancer research 20081001 |
Bimetallic dendrimer-encapsulated nanoparticles as catalysts: a review of the research advances. | Chemical Society reviews 20080801 |
HPRT mutations in lymphocytes from 1,3-butadiene-exposed workers in China. | Environmental health perspectives 20080201 |
Catalytic performance of symmetrical and unsymmetrical sulfur-containing pincer complexes: synthesis and tandem catalytic activity of the first PCS-pincer palladium complex. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
Development of a physiologically based toxicokinetic model for butadiene and four major metabolites in humans: global sensitivity analysis for experimental design issues. | Chemico-biological interactions 20070501 |
Metabolism of 1,3-butadiene to toxicologically relevant metabolites in single-exposed mice and rats. | Chemico-biological interactions 20070320 |
Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites. | Chemico-biological interactions 20070320 |
Synthesis of DNA oligodeoxynucleotides containing structurally defined N6-(2-hydroxy-3-buten-1-yl)-adenine adducts of 3,4-epoxy-1-butene. | Chemico-biological interactions 20070320 |
Mutagenicity of stereochemical configurations of 1,2-epoxybutene and 1,2:3,4-diepoxybutane in human lymphblastoid cells. | Chemico-biological interactions 20070320 |
Quantitative analysis of N-terminal valine peptide adducts specific for 1,2-epoxy-3-butene. | Chemico-biological interactions 20070320 |
N-terminal globin adducts as biomarkers for formation of butadiene derived epoxides. | Chemico-biological interactions 20070320 |
Identification of covalent modifications in P450 2E1 by 1,2-epoxy-3-butene in vitro. | Chemico-biological interactions 20070320 |
Copper-catalyzed rearrangement of vinyl oxiranes. | Journal of the American Chemical Society 20061220 |
Palladium-catalyzed DYKAT of butadiene monoepoxide: enantioselective total synthesis of (+)-DMDP, (-)-bulgecinine, and (+)-broussonetine G. | Chemistry (Weinheim an der Bergstrasse, Germany) 20060825 |
3,4-Epoxy-1-butene, a reactive metabolite of 1,3-butadiene, induces somatic mutations in Xpc-null mice. | Environmental and molecular mutagenesis 20060101 |
Cellular analysis of disorazole C and structure-activity relationship of analogs of the natural product. | Chemical biology & drug design 20060101 |
Hemoglobin adducts and micronuclei in rodents after treatment with isoprene monoxide or butadiene monoxide. | Mutation research 20050801 |
Structure of an oligodeoxynucleotide containing a butadiene oxide-derived N1 beta-hydroxyalkyl deoxyinosine adduct in the human N-ras codon 61 sequence. | Biochemistry 20050308 |
Regio- and stereoselectivity of the addition of O-, S-, N-, and C-nucleophiles to the beta vinyl oxirane derived from D-glucal. | The Journal of organic chemistry 20041210 |
Effects of 1,3-butadiene, isoprene, and their photochemical degradation products on human lung cells. | Environmental health perspectives 20041101 |
Stereospecific uncatalyzed alpha-O-glycosylation and alpha-C-glycosidation by means of a new D-Gulal-derived alpha vinyl oxirane. | The Journal of organic chemistry 20041015 |
Synthesis of chiral phosphoantigens and their activity in gamma delta T cell stimulation. | Bioorganic & medicinal chemistry letters 20040906 |
DNA adducts in rats and mice following exposure to [4-14C]-1,2-epoxy-3-butene and to [2,3-14C]-1,3-butadiene. | Chemico-biological interactions 20040630 |
Characterization of alkyl-cobalamins formed on trapping of epoxide metabolites of 1,3-butadiene. | Journal of separation science 20040501 |
Dose responses for DNA adduct formation in tissues of rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-[(14)C]-butadiene. | Chemico-biological interactions 20040315 |
Dose responses for the formation of hemoglobin adducts and urinary metabolites in rats and mice exposed by inhalation to low concentrations of 1,3-[2,3-(14)C]-butadiene. | Chemico-biological interactions 20040315 |
Identification and characterization of a series of nucleoside adducts formed by the reaction of 2'-deoxyguanosine and 1,2,3,4-diepoxybutane under physiological conditions. | Chemical research in toxicology 20031201 |
Genetic susceptibility, biomarker respones, and cancer. | Mutation research 20031101 |
Mutagenic spectrum of butadiene-derived N1-deoxyinosine adducts and N6,N6-deoxyadenosine intrastrand cross-links in mammalian cells. | Chemical research in toxicology 20021201 |
New stereoselective beta-glycosylation via a vinyl oxirane derived from D-glucal. | Organic letters 20021017 |
Synthesis and characterization of water-soluble hydroxybutenyl cyclomaltooligosaccharides (cyclodextrins). | Carbohydrate research 20020315 |
Enantioselective allylation of beta,gamma-unsaturated aldehydes generated via Lewis acid induced rearrangement of 2-vinyloxiranes. | Organic letters 20020110 |
Dose-dependent excretion of unconjugated 3-butene-1,2-diol measured in urine with a gc/ms after 1,3-butadiene exposure. | Toxicology mechanisms and methods 20020101 |
Metabolism of butadiene monoxide by freshly isolated hepatocytes from mice and rats: different partitioning between oxidative, hydrolytic, and conjugation pathways. | Drug metabolism and disposition: the biological fate of chemicals 20010601 |
Cellular and molecular basis for species, sex and tissue differences in 1,3-butadiene metabolism. | Chemico-biological interactions 20010601 |
First-pass metabolism of 1,3-butadiene in once-through perfused livers of rats and mice. | Chemico-biological interactions 20010601 |
Physiological modeling of butadiene disposition in mice and rats. | Chemico-biological interactions 20010601 |
Development of a preliminary physiologically based toxicokinetic (PBTK) model for 1,3-butadiene risk assessment. | Chemico-biological interactions 20010601 |
Mutational spectrum of 1,3-butadiene and metabolites 1,2-epoxybutene and 1,2,3,4-diepoxybutane to assess mutagenic mechanisms. | Chemico-biological interactions 20010601 |
Advances in the mass spectrometry of hemoglobin adducts: global analysis of the covalent binding of butadiene monoxide. | Chemico-biological interactions 20010601 |
A novel DNA adduct, originating from 1,2-epoxy-3,4-butanediol, is the major DNA adduct after exposure to [2,3-(14)C]-1,3-butadiene,[4-(14)C]-1,2-epoxy-3-butane. | Chemico-biological interactions 20010601 |
In vitro genotoxicity testing of (1-chloroethenyl)oxirane, a metabolite of beta-chloroprene. | Chemico-biological interactions 20010601 |
Synthesis and characterization of oligodeoxynucleotides containing an N1 beta-hydroxyalkyl adduct of 2'-deoxyinosine. | Chemical research in toxicology 20010601 |
Synthesis and characterization of nucleosides and oligonucleotides bearing adducts of butadiene epoxides on adenine n(6) and guanine n(2). | Chemical research in toxicology 20010401 |
Lung-specific mutagenicity and mutational spectrum in B6C3F1 lacI transgenic mice following inhalation exposure to 1,2-epoxybutene. | Mutation research 20010125 |
Hemoglobin adducts of epoxybutene in workers occupationally exposed to 1,3-butadiene. | Archives of toxicology 20010101 |
Reactive metabolites of 1,3-butadiene: DNA and hemoglobin adduct formation and potential roles in carcinogenicity. | Advances in experimental medicine and biology 20010101 |
Point mutations induced by 1,2-epoxy-3-butene N1 deoxyinosine adducts. | Environmental and molecular mutagenesis 20010101 |
1,3-Butadiene oxidation by human myeloperoxidase. Role of chloride ion in catalysis of divergent pathways. | The Journal of biological chemistry 19921005 |