Home Nitriles 3,3'-Iminodipropionitrile

3,3'-Iminodipropionitrile

CAS No.:
111-94-4
Catalog Number:
AG0033HU
Molecular Formula:
C6H9N3
Molecular Weight:
123.1558
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
90%
In Stock USA
United States
$13
- +
25g
90%
In Stock USA
United States
$19
- +
100g
90%
In Stock USA
United States
$50
- +
Product Description
Catalog Number:
AG0033HU
Chemical Name:
3,3'-Iminodipropionitrile
CAS Number:
111-94-4
Molecular Formula:
C6H9N3
Molecular Weight:
123.1558
MDL Number:
MFCD00001956
IUPAC Name:
3-(2-cyanoethylamino)propanenitrile
InChI:
InChI=1S/C6H9N3/c7-3-1-5-9-6-2-4-8/h9H,1-2,5-6H2
InChI Key:
SBAJRGRUGUQKAF-UHFFFAOYSA-N
SMILES:
N#CCCNCCC#N
UNII:
3XP1CVU865
NSC Number:
7770
UN Number:
3334
Properties
Complexity:
126  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
123.08g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
123.159g/mol
Monoisotopic Mass:
123.08g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
59.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.8  
Literature
Title Journal
Strain and Sex Differences in the Vestibular and Systemic Toxicity of 3,3'-Iminodipropionitrile in Mice. Toxicological sciences : an official journal of the Society of Toxicology 20170301
Maternal exposure to 3,3'-iminodipropionitrile targets late-stage differentiation of hippocampal granule cell lineages to affect brain-derived neurotrophic factor signaling and interneuron subpopulations in rat offspring. Journal of applied toxicology : JAT 20150801
Acute toxic effects of 3,3'-iminodipropionitrile on hypothalamic-pituitary-gonadal axis in male rats. Reproductive toxicology (Elmsford, N.Y.) 20140101
Surface chemical conversion of 3-glycidoxypropyldimethylethoxysilane on hydroxylated silicon surface: FT-IR, contact angle and ellipsometry analysis. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201
N-nitro-L-arginine, a nitric oxide synthase inhibitor, aggravates iminodipropionitrile-induced neurobehavioral and vestibular toxicities in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20121101
Vestibular toxicity of cis-2-pentenenitrile in the rat. Toxicology letters 20120620
The involvement of neurofilament heavy chain phosphorylation in the maturation and degeneration of rat oocytes. Endocrinology 20120401
Loss of neurofilaments in the neuromuscular junction in a rat model of proximal axonopathy. Neuropathology and applied neurobiology 20120201
Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse. Toxicology letters 20120125
Acute reproductive toxicity of 3,3'-iminodipropionitrile in female rats. Reproductive toxicology (Elmsford, N.Y.) 20120101
Domino alkylation/oxa-Michael of 1,3-cyclohexanediones: steering the C/O-chemoselectivity to reach tetrahydrobenzofuranones. Organic & biomolecular chemistry 20111007
Selective atonal gene delivery improves balance function in a mouse model of vestibular disease. Gene therapy 20110901
A new unifying hypothesis for lathyrism, konzo and tropical ataxic neuropathy: nitriles are the causative agents. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110301
Butenenitriles have low axonopathic potential in the rat. Toxicology letters 20110205
Clinical physiology and mechanism of dizocilpine (MK-801): electron transfer, radicals, redox metabolites and bioactivity. Oxidative medicine and cellular longevity 20100101
Nervous and vestibular toxicities of acrylonitrile and iminodipropionitrile. Toxicological sciences : an official journal of the Society of Toxicology 20090701
Pentoxifylline attenuates iminodipropionitrile-induced behavioral abnormalities in rats. Behavioural pharmacology 20090701
Neurovestibular toxicities of acrylonitrile and iminodipropionitrile in rats: a comparative evaluation of putative mechanisms and target sites. Toxicological sciences : an official journal of the Society of Toxicology 20090501
Phosphorylation and compactness of neurofilaments in multiple sclerosis: indicators of axonal pathology. Experimental neurology 20081001
[Curative effect and possible mechanisms of topiramate in treatment of Tourette syndrome in rats]. Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20080801
Requirement of vimentin filament assembly for beta3-adrenergic receptor activation of ERK MAP kinase and lipolysis. The Journal of biological chemistry 20070323
Behavioral disturbances and hair cell loss in the inner ear following nitrile exposure in mice, guinea pigs, and frogs. Toxicological sciences : an official journal of the Society of Toxicology 20070301
Protective effect of hydrocortisone on iminodipropionitrile-induced neurotoxicity in rats. Basic & clinical pharmacology & toxicology 20070301
Propagation of scrapie in peripheral nerves after footpad infection in normal and neurotoxin exposed hamsters. Veterinary research 20070101
Mechanism of neurotoxic 3,3'-iminodipropionitrile: relation to unsaturated nitriles, cocaine, and reactive oxygen species. Medical hypotheses 20060101
Behavioral and pathological effects in the rat define two groups of neurotoxic nitriles. Toxicological sciences : an official journal of the Society of Toxicology 20051201
Does copper ameliorate the vestibular toxicity of iminodipropionitrile (IDPN)? Neurotoxicology 20050601
Extruding auditory hair cells in rats exposed to subchronic 3,3'-iminodipropionitrile. Environmental toxicology and pharmacology 20050501
The neurotoxicity of iminodipropionitrile (IDPN) is ameliorated by copper. Neurotoxicology 20050301
Role of oxidative metabolites of cocaine in toxicity and addiction: oxidative stress and electron transfer. Medical hypotheses 20050101
On the similarity of cocaine and 3,3'-iminodipropionitrile. Medical hypotheses 20050101
Sodium benzoate attenuates iminodipropionitrile-induced behavioral syndrome in rats. Behavioural pharmacology 20041201
Metoclopramide attenuates iminodipropionitrile-induced oxidative stress and neurobehavioral toxicity in rats. Pharmacology, biochemistry, and behavior 20041101
Retinal microvascular patency in the diabetic rat. International ophthalmology 20040701
Inhibitory effect of free radical scavenger, MCI-186, in the increase of hydroxyl radical induced by iminodipropionitrile in rats. Journal of the neurological sciences 20040415
Distal effects in a model of proximal axonopathy: 3,3'-iminodipropionitrile causes specific loss of neurofilaments in rat vestibular afferent endings. Acta neuropathologica 20031101
Influence of age on iminodipropionitrile-induced vestibular and neurobehavioral toxicities in rats. Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030901
Expression of neurotransmitter genes in motor regions of the dyskinetic rat after iminodipropionitrile. Neuroscience letters 20030814
A hypothetical mathematical construct explaining the mechanism of biological amplification in an experimental model utilizing picoTesla (PT) electromagnetic fields. Medical hypotheses 20030601
[Neurobehavioral toxicity of acrylamide and IDPN (3,3'-iminodipropionitrile) in rats by 28-day oral administration--problems encountered in collaborative study and a commentary on conducting neurobehavioral testing]. The Journal of toxicological sciences 20030501
Comparison of cis- and trans-crotononitrile effects in the rat reveals specificity in the neurotoxic properties of nitrile isomers. Toxicology and applied pharmacology 20030301
Three-dimensional mapping of the lesions induced by beta-beta'-iminodiproprionitrile, methyl iodide and methyl methacrylate in the rat nasal cavity. Toxicologic pathology 20030101
Attenuation of iminodipropionitrile induced behavioral syndrome by sodium salicylate in rats. Pharmacology, biochemistry, and behavior 20021001
Masses of phosphorylated neurofilaments are associated with abnormal golgi apparatus of anterior horn neurons of beta, beta'-iminodipropionitrile-intoxicated rats. Neuropathology : official journal of the Japanese Society of Neuropathology 20020601
Relationship between insult intensity and mode of hair cell loss in the vestibular system of rats exposed to 3,3'-iminodipropionitrile. The Journal of comparative neurology 20011029
Pathology of the rat vestibular sensory epithelia during subchronic 3,3'-iminodipropionitrile exposure: hair cells may not be the primary target of toxicity. Acta neuropathologica 20011001
Behavioural disturbances and sensory pathology following allylnitrile exposure in rats. Brain research 20010622
Characterization of olfactory deficits in the rat following administration of 2,6-dichlorobenzonitrile (dichlobenil), 3,3'-iminodipropionitrile, or methimazole. Fundamental and applied toxicology : official journal of the Society of Toxicology 19960101
The ototoxicity of 3,3'-iminodipropionitrile: functional and morphological evidence of cochlear damage. Hearing research 19941101
Properties