3,3'-Iminodipropionitrile
Title | Journal |
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Strain and Sex Differences in the Vestibular and Systemic Toxicity of 3,3'-Iminodipropionitrile in Mice. | Toxicological sciences : an official journal of the Society of Toxicology 20170301 |
Maternal exposure to 3,3'-iminodipropionitrile targets late-stage differentiation of hippocampal granule cell lineages to affect brain-derived neurotrophic factor signaling and interneuron subpopulations in rat offspring. | Journal of applied toxicology : JAT 20150801 |
Acute toxic effects of 3,3'-iminodipropionitrile on hypothalamic-pituitary-gonadal axis in male rats. | Reproductive toxicology (Elmsford, N.Y.) 20140101 |
Surface chemical conversion of 3-glycidoxypropyldimethylethoxysilane on hydroxylated silicon surface: FT-IR, contact angle and ellipsometry analysis. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121201 |
N-nitro-L-arginine, a nitric oxide synthase inhibitor, aggravates iminodipropionitrile-induced neurobehavioral and vestibular toxicities in rats. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20121101 |
Vestibular toxicity of cis-2-pentenenitrile in the rat. | Toxicology letters 20120620 |
The involvement of neurofilament heavy chain phosphorylation in the maturation and degeneration of rat oocytes. | Endocrinology 20120401 |
Loss of neurofilaments in the neuromuscular junction in a rat model of proximal axonopathy. | Neuropathology and applied neurobiology 20120201 |
Role of CYP2E1-mediated metabolism in the acute and vestibular toxicities of nineteen nitriles in the mouse. | Toxicology letters 20120125 |
Acute reproductive toxicity of 3,3'-iminodipropionitrile in female rats. | Reproductive toxicology (Elmsford, N.Y.) 20120101 |
Domino alkylation/oxa-Michael of 1,3-cyclohexanediones: steering the C/O-chemoselectivity to reach tetrahydrobenzofuranones. | Organic & biomolecular chemistry 20111007 |
Selective atonal gene delivery improves balance function in a mouse model of vestibular disease. | Gene therapy 20110901 |
A new unifying hypothesis for lathyrism, konzo and tropical ataxic neuropathy: nitriles are the causative agents. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110301 |
Butenenitriles have low axonopathic potential in the rat. | Toxicology letters 20110205 |
Clinical physiology and mechanism of dizocilpine (MK-801): electron transfer, radicals, redox metabolites and bioactivity. | Oxidative medicine and cellular longevity 20100101 |
Nervous and vestibular toxicities of acrylonitrile and iminodipropionitrile. | Toxicological sciences : an official journal of the Society of Toxicology 20090701 |
Pentoxifylline attenuates iminodipropionitrile-induced behavioral abnormalities in rats. | Behavioural pharmacology 20090701 |
Neurovestibular toxicities of acrylonitrile and iminodipropionitrile in rats: a comparative evaluation of putative mechanisms and target sites. | Toxicological sciences : an official journal of the Society of Toxicology 20090501 |
Phosphorylation and compactness of neurofilaments in multiple sclerosis: indicators of axonal pathology. | Experimental neurology 20081001 |
[Curative effect and possible mechanisms of topiramate in treatment of Tourette syndrome in rats]. | Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics 20080801 |
Requirement of vimentin filament assembly for beta3-adrenergic receptor activation of ERK MAP kinase and lipolysis. | The Journal of biological chemistry 20070323 |
Behavioral disturbances and hair cell loss in the inner ear following nitrile exposure in mice, guinea pigs, and frogs. | Toxicological sciences : an official journal of the Society of Toxicology 20070301 |
Protective effect of hydrocortisone on iminodipropionitrile-induced neurotoxicity in rats. | Basic & clinical pharmacology & toxicology 20070301 |
Propagation of scrapie in peripheral nerves after footpad infection in normal and neurotoxin exposed hamsters. | Veterinary research 20070101 |
Mechanism of neurotoxic 3,3'-iminodipropionitrile: relation to unsaturated nitriles, cocaine, and reactive oxygen species. | Medical hypotheses 20060101 |
Behavioral and pathological effects in the rat define two groups of neurotoxic nitriles. | Toxicological sciences : an official journal of the Society of Toxicology 20051201 |
Does copper ameliorate the vestibular toxicity of iminodipropionitrile (IDPN)? | Neurotoxicology 20050601 |
Extruding auditory hair cells in rats exposed to subchronic 3,3'-iminodipropionitrile. | Environmental toxicology and pharmacology 20050501 |
The neurotoxicity of iminodipropionitrile (IDPN) is ameliorated by copper. | Neurotoxicology 20050301 |
Role of oxidative metabolites of cocaine in toxicity and addiction: oxidative stress and electron transfer. | Medical hypotheses 20050101 |
On the similarity of cocaine and 3,3'-iminodipropionitrile. | Medical hypotheses 20050101 |
Sodium benzoate attenuates iminodipropionitrile-induced behavioral syndrome in rats. | Behavioural pharmacology 20041201 |
Metoclopramide attenuates iminodipropionitrile-induced oxidative stress and neurobehavioral toxicity in rats. | Pharmacology, biochemistry, and behavior 20041101 |
Retinal microvascular patency in the diabetic rat. | International ophthalmology 20040701 |
Inhibitory effect of free radical scavenger, MCI-186, in the increase of hydroxyl radical induced by iminodipropionitrile in rats. | Journal of the neurological sciences 20040415 |
Distal effects in a model of proximal axonopathy: 3,3'-iminodipropionitrile causes specific loss of neurofilaments in rat vestibular afferent endings. | Acta neuropathologica 20031101 |
Influence of age on iminodipropionitrile-induced vestibular and neurobehavioral toxicities in rats. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20030901 |
Expression of neurotransmitter genes in motor regions of the dyskinetic rat after iminodipropionitrile. | Neuroscience letters 20030814 |
A hypothetical mathematical construct explaining the mechanism of biological amplification in an experimental model utilizing picoTesla (PT) electromagnetic fields. | Medical hypotheses 20030601 |
[Neurobehavioral toxicity of acrylamide and IDPN (3,3'-iminodipropionitrile) in rats by 28-day oral administration--problems encountered in collaborative study and a commentary on conducting neurobehavioral testing]. | The Journal of toxicological sciences 20030501 |
Comparison of cis- and trans-crotononitrile effects in the rat reveals specificity in the neurotoxic properties of nitrile isomers. | Toxicology and applied pharmacology 20030301 |
Three-dimensional mapping of the lesions induced by beta-beta'-iminodiproprionitrile, methyl iodide and methyl methacrylate in the rat nasal cavity. | Toxicologic pathology 20030101 |
Attenuation of iminodipropionitrile induced behavioral syndrome by sodium salicylate in rats. | Pharmacology, biochemistry, and behavior 20021001 |
Masses of phosphorylated neurofilaments are associated with abnormal golgi apparatus of anterior horn neurons of beta, beta'-iminodipropionitrile-intoxicated rats. | Neuropathology : official journal of the Japanese Society of Neuropathology 20020601 |
Relationship between insult intensity and mode of hair cell loss in the vestibular system of rats exposed to 3,3'-iminodipropionitrile. | The Journal of comparative neurology 20011029 |
Pathology of the rat vestibular sensory epithelia during subchronic 3,3'-iminodipropionitrile exposure: hair cells may not be the primary target of toxicity. | Acta neuropathologica 20011001 |
Behavioural disturbances and sensory pathology following allylnitrile exposure in rats. | Brain research 20010622 |
Characterization of olfactory deficits in the rat following administration of 2,6-dichlorobenzonitrile (dichlobenil), 3,3'-iminodipropionitrile, or methimazole. | Fundamental and applied toxicology : official journal of the Society of Toxicology 19960101 |
The ototoxicity of 3,3'-iminodipropionitrile: functional and morphological evidence of cochlear damage. | Hearing research 19941101 |