Home Other Building Blocks 2-Pyrrolidone

2-Pyrrolidone

CAS No.:
616-45-5
Catalog Number:
AG0033FT
Molecular Formula:
C4H7NO
Molecular Weight:
85.1045
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25g
95%
In Stock USA
United States
$25
- +
100g
99%(GC)
In Stock USA
United States
$57
- +
500g
99%(GC)
In Stock USA
United States
$101
- +
Product Description
Catalog Number:
AG0033FT
Chemical Name:
2-Pyrrolidone
CAS Number:
616-45-5
Molecular Formula:
C4H7NO
Molecular Weight:
85.1045
MDL Number:
MFCD19217896
IUPAC Name:
pyrrolidin-2-one
InChI:
InChI=1S/C4H7NO/c6-4-2-1-3-5-4/h1-3H2,(H,5,6)
InChI Key:
HNJBEVLQSNELDL-UHFFFAOYSA-N
SMILES:
O=C1CCCN1
EC Number:
210-483-1
UNII:
KKL5D39EOL
RTECS Number:
UY5715000
Properties
Complexity:
69.9  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
85.053g/mol
Formal Charge:
0
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
85.106g/mol
Monoisotopic Mass:
85.053g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
29.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.8  
Literature
Title Journal
Microstructure-stability relations studies of porous chitosan microspheres supported palladium catalysts. International journal of biological macromolecules 20121201
A framework for identifying characteristic odor compounds in municipal wastewater effluent. Water research 20121115
Asymmetric synthesis of the fully elaborated pyrrolidinone core of oxazolomycin A. Organic letters 20121102
Phenolic alkaloids from the aerial parts of Dracocephalum heterophyllum. Phytochemistry 20121001
Polyvinyl alcohol-polyvinyl pyrrolidone thin films provide local short-term release of anti-inflammatory agents post spinal cord injury. Journal of biomedical materials research. Part B, Applied biomaterials 20121001
Antimicrobial activity of bioactive compounds and leaf extracts in Jatropha tanjorensis. Fitoterapia 20121001
(1-{(E)-[Phen-yl(pyridin-2-yl-κN)methyl-idene]amino-κN}pyrrolidin-2-one-κO)bis-(thio-cyanato-κN)copper(II). Acta crystallographica. Section E, Structure reports online 20121001
(8aR,9R)-9-Hy-droxy-7,8,8a,9-tetra-hydro-furo[3,2-f]indolizin-6(4H)-one. Acta crystallographica. Section E, Structure reports online 20121001
Differences in the volatile compositions of ginseng species (Panax sp.). Journal of agricultural and food chemistry 20120808
Surface modification of PAMAM dendrimer improves its biocompatibility. Nanomedicine : nanotechnology, biology, and medicine 20120801
In vitro and in vivo evaluation of novel osmotic pump tablets of isosorbide-5-mononitrate containing polyvinyl pyrrolidone (PVP) for controlled release. Die Pharmazie 20120801
Efficient iodine catalyzed three components domino reaction for the synthesis of 1-((phenylthio)(phenyl)methyl)pyrrolidin-2-one derivatives possessing anticancer activities. Organic & biomolecular chemistry 20120728
Design, synthesis, and biological and structural evaluations of novel HIV-1 protease inhibitors to combat drug resistance. Journal of medicinal chemistry 20120726
Production, recovery and purification of a recombinant β-galactosidase by expanded bed anion exchange adsorption. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120701
1'-Methyl-4'-(4-methyl-phen-yl)dispiro-[indane-2,3'-pyrrolidine-2',3''-indoline]-1,2''-dione. Acta crystallographica. Section E, Structure reports online 20120701
Structure elucidation of new fusarins revealing insights in the rearrangement mechanisms of the Fusarium mycotoxin fusarin C. Journal of agricultural and food chemistry 20120530
Nanotoxicity of gold and gold-cobalt nanoalloy. Chemical research in toxicology 20120521
pH-responsive surface activity and solubilization with novel pyrrolidone-based Gemini surfactants. Langmuir : the ACS journal of surfaces and colloids 20120508
A novel property of spider silk: chemical defence against ants. Proceedings. Biological sciences 20120507
Effects of glutamate decarboxylase and gamma-aminobutyric acid (GABA) transporter on the bioconversion of GABA in engineered Escherichia coli. Bioprocess and biosystems engineering 20120501
Surface modification of poly(styrene-b-(ethylene-co-butylene)-b-styrene) elastomer via UV-induced graft polymerization of N-vinyl pyrrolidone. Colloids and surfaces. B, Biointerfaces 20120501
Carbonyl-bis-(triphenyl-phosphane-κP)(η(2)-1-vinyl-pyrrolidin-2-one-κO)ruthenium(0). Acta crystallographica. Section E, Structure reports online 20120501
Close association of aquaporin-2 internalization with caveolin-1. Acta histochemica et cytochemica 20120426
Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1'-pyrrolidinone ring. Journal of medicinal chemistry 20120412
Preparation and characterization of magnetizable aerosols. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120411
A search for BACE inhibitors reveals new biosynthetically related pyrrolidones, furanones and pyrroles from a southern Australian marine sponge, Ianthella sp. Organic & biomolecular chemistry 20120407
Comparison of in vitro methods of measuring mucoadhesion: ellipsometry, tensile strength and rheological measurements. Colloids and surfaces. B, Biointerfaces 20120401
(6S,7S,8S,8aS)-6-Ethyl-3-oxo-1,2,3,5,6,7,8,8a-octa-hydro-indolizine-7,8-diyl diacetate. Acta crystallographica. Section E, Structure reports online 20120301
1,1'-[(2-Bromo-phen-yl)-methyl-ene]-dipyrrolidin-2-one. Acta crystallographica. Section E, Structure reports online 20120301
Improved compressibility, flowability, dissolution and bioavailability of pioglitazone hydrochloride by emulsion solvent diffusion with additives. Die Pharmazie 20120301
[Synthesis and characterization of mixed metal oxide pigments]. Guang pu xue yu guang pu fen xi = Guang pu 20120301
Room temperature aqueous synthesis of bipyramidal silver nanostructures. Journal of nanoscience and nanotechnology 20120301
Controllable synthesis of ZnO with various morphologies by hydrothermal method. Journal of nanoscience and nanotechnology 20120301
New investigation in PVP-mediated synthesis of noble metallic nanomaterials. Journal of nanoscience and nanotechnology 20120301
Effects of fullerene C60 nanocomposites on human platelet aggregation. Bulletin of experimental biology and medicine 20120301
Control of chemical kinetics for sub-10 nm Cu nanoparticles to fabricate highly conductive ink below 150 °C. Nanotechnology 20120217
Simultaneous 16S and 18S rRNA fluorescence in situ hybridization (FISH) on LR White sections demonstrated in Vestimentifera (Siboglinidae) tubeworms. Acta histochemica 20120201
New frontier in hypericin-mediated diagnosis of cancer with current optical technologies. Annals of biomedical engineering 20120201
Synthesis of nestlike ZnO hierarchically porous structures and analysis of their gas sensing properties. ACS applied materials & interfaces 20120201
Hydrothermal synthesis of ZnO nanorods in the presence of a surfactant. Journal of nanoscience and nanotechnology 20120201
Cubic phase-forming dry powders for controlled drug delivery on mucosal surfaces. Journal of controlled release : official journal of the Controlled Release Society 20120130
Design and evaluation of ocular drug delivery system for controlled delivery of gatifloxacin sesquehydrate: In vitro and in vivo evaluation. Pharmaceutical development and technology 20120101
Biocompatibility evaluation of a new hydrogel dressing based on polyvinylpyrrolidone/polyethylene glycol. Journal of biomedicine & biotechnology 20120101
Evaluation of zebrafish (Danio rerio) PGCs viability and DNA damage using different cryopreservation protocols. Theriogenology 20120101
Gelam (Melaleuca spp.) Honey-Based Hydrogel as Burn Wound Dressing. Evidence-based complementary and alternative medicine : eCAM 20120101
Use of quantitative structure-enantioselective retention relationship for the liquid chromatography chiral separation prediction of the series of pyrrolidin-2-one compounds. Chirality 20120101
In Vivo Toxicity of Silver Nanoparticles and Silver Ions in Zebrafish (Danio rerio). Journal of toxicology 20120101
Ethyl 2-(4-nitro-phen-yl)-1-[3-(2-oxopyrrolidin-1-yl)prop-yl]-1H-benzimidazole-5-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20120101
Ethyl 2-(4-hy-droxy-3-meth-oxy-phen-yl)-1-[3-(2-oxopyrrolidin-1-yl)prop-yl]-1H-benzimidazole-5-carboxyl-ate monohydrate. Acta crystallographica. Section E, Structure reports online 20120101
Preservation of mouse sperm by convective drying and storing in 3-O-methyl-D-glucose. PloS one 20120101
Zwitterionic chitosan derivative, a new biocompatible pharmaceutical excipient, prevents endotoxin-mediated cytokine release. PloS one 20120101
Link between intestinal CD36 ligand binding and satiety induced by a high protein diet in mice. PloS one 20120101
Expression, immobilization and enzymatic properties of glutamate decarboxylase fused to a cellulose-binding domain. International journal of molecular sciences 20120101
Magnetic nanoparticles: preparation, physical properties, and applications in biomedicine. Nanoscale research letters 20120101
Sesbania mosaic virus (SeMV) infectious clone: possible mechanism of 3' and 5' end repair and role of polyprotein processing in viral replication. PloS one 20120101
Improved oral bioavailability of poorly water-soluble indirubin by a supersaturatable self-microemulsifying drug delivery system. International journal of nanomedicine 20120101
Identification of a new rhoptry neck complex RON9/RON10 in the Apicomplexa parasite Toxoplasma gondii. PloS one 20120101
Leishmania amazonensis arginase compartmentalization in the glycosome is important for parasite infectivity. PloS one 20120101
Design and evaluation of patches for transdermal delivery of losartan potassium. PDA journal of pharmaceutical science and technology 20120101
Molecular dynamics simulation study and hybrid pharmacophore model development in human LTA4H inhibitor design. PloS one 20120101
Monodispersed molecularly imprinted polymer for creatinine by modified precipitation polymerization. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101
Successfully improving ocular drug delivery using the cationic nanoemulsion, novasorb. Journal of drug delivery 20120101
Synthesis of Li(1+x)V3O8 by chemical route and its characterization. Journal of nanoscience and nanotechnology 20120101
Polymer brushes on carbon nanotubes by thiol-lactam initiated radical polymerization of 2-hydroxyethyl methacrylate. Journal of nanoscience and nanotechnology 20120101
Crystal structure of a new benzoic acid inhibitor of influenza neuraminidase bound with a new tilt induced by overpacking subsite C6. BMC structural biology 20120101
Controlled synthesis and characterization of hollow flower-like silver nanostructures. International journal of nanomedicine 20120101
Macromolecular crowding directs extracellular matrix organization and mesenchymal stem cell behavior. PloS one 20120101
Preparation and application of amino functionalized mesoporous nanofiber membrane via electrospinning for adsorption of Cr3+ from aqueous solution. Journal of environmental sciences (China) 20120101
Room temperature radiolytic synthesized Cu@CuAlO(2)-Al(2)O(3) nanoparticles. International journal of molecular sciences 20120101
The possible mechanism of hypotensive activity of some pyrrolidin-2-one derivatives with antagonist properties at alpha1-adrenoceptors. European journal of pharmacology 20111230
Collection of peptides released from single neurons with particle-embedded monolithic capillaries followed by detection with matrix-assisted laser desorption/ionization mass spectrometry. Analytical chemistry 20111215
Adaptation of the Se301 insect cell line to suspension culture. Effect of turbulence on growth and on production of nucleopolyhedrovius (SeMNPV). Cytotechnology 20111201
Hydrogen-bonded structures of the 1:1 and 1:2 compounds of chloranilic acid with pyrrolidin-2-one and piperidin-2-one. Acta crystallographica. Section C, Crystal structure communications 20111201
A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor. PLoS pathogens 20111201
Ethyl 4-acetamido-3-acet-oxy-2-benzyl-3-methyl-butano-ate. Acta crystallographica. Section E, Structure reports online 20111201
Formulation and evaluation of an in situ gel forming system for controlled delivery of triptorelin acetate. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120
Development and validation of a liquid chromatographic method for the simultaneous determination of aniracetam and its related substances in the bulk drug and a tablet formulation. Journal of pharmaceutical and biomedical analysis 20111101
Odorous compounds in municipal wastewater effluent and potable water reuse systems. Environmental science & technology 20111101
Sap transporter mediated import and subsequent degradation of antimicrobial peptides in Haemophilus. PLoS pathogens 20111101
Methyl (9aR*,10S*,11R*,13aS*,13bS*)-9-oxo-6,7,9,9a,10,11-hexa-hydro-5H,13bH-11,13a-ep-oxy-pyrrolo-[2',1':3,4][1,4]diazepino[2,1-a]isoindole-10-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20111101
(6aS*,6bS*,11R*,11aR*)-6-(2-Furyl-methyl)-5,12-dioxo-5,6,6a,6b,7,11,11a,12-octa-hydro-furo[3',2':5,6]isoindolo[2,1-a]quinazoline-11-carb-oxy-lic acid. Acta crystallographica. Section E, Structure reports online 20111101
3,5-dimethylisoxazoles act as acetyl-lysine-mimetic bromodomain ligands. Journal of medicinal chemistry 20111013
pH-sensitive hydrogels based on semi-interpenetrating network (semi-IPN) of chitosan and polyvinyl pyrrolidone for clarithromycin release. Drug development and industrial pharmacy 20111001
Lecithin-based novel cationic nanocarriers (LeciPlex) I: fabrication, characterization and evaluation. Nanomedicine (London, England) 20111001
(S)-5-Oxo-N-phenyl-pyrrolidine-2-carboxamide. Acta crystallographica. Section E, Structure reports online 20111001
CaCu3Ti4O12 nanoparticles using polyvinyl pyrrolidone: synthesis and dielectric properties. Journal of nanoscience and nanotechnology 20111001
Analysis of the grafting process of PVP on a silicon surface by AFM and contact angle. Langmuir : the ACS journal of surfaces and colloids 20110920
Immobilization of Saccharomyces cerevisiae on to modified carboxymethylcellulose for production of ethanol. Bioprocess and biosystems engineering 20110901
In vitro and in vivo characterization of novel biomaterial for transdermal application. Current drug delivery 20110901
Violacein and related tryptophan metabolites produced by Chromobacterium violaceum: biosynthetic mechanism and pathway for construction of violacein core. Applied microbiology and biotechnology 20110901
Hydrogen-independent reductive transformation of carbohydrate biomass into γ-valerolactone and pyrrolidone derivatives with supported gold catalysts. Angewandte Chemie (International ed. in English) 20110816
(8aRS)-8,8a-Dihydro-furo[3,2-f]indolizine-6,9(4H,7H)-dione. Acta crystallographica. Section E, Structure reports online 20110801
Preparation of polymeric nanoparticles of cyclosporin A using infrared pulsed laser. International journal of pharmaceutics 20110729
Synthesis of 3-guaninyl- and 3-adeninyl-5-hydroxymethyl-2-pyrrolidinone nucleosides. The Journal of organic chemistry 20110715
Acoustic cavitation for engineering of gold sols in silver nitrate solutions. Ultrasonics sonochemistry 20110701
Exploration of photochemical reactions of N-trimethylsilylmethyl-substituted uracil, pyridone, and pyrrolidone derivatives. Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology 20110701
Suppression of the TRIF-dependent signaling pathway of toll-like receptors by (E)-isopropyl 4-oxo-4-(2-oxopyrrolidin-1-yl)-2-butenoate. BMB reports 20110701
New insights into the mucoadhesion of pectins by AFM roughness parameters in combination with SPR. International journal of pharmaceutics 20110615
Synthesis of nickel bowl-like nanoparticles and their doping for inducing planar alignment of a nematic liquid crystal. Journal of the American Chemical Society 20110608
QbD approach of rapid disintegrating tablets incorporating indomethacin solid dispersion. Pharmaceutical development and technology 20110601
The effects of macromolecular and serum supplements and oxygen tension during bovine in vitro procedures on kinetics of oocyte maturation and embryo development. In vitro cellular & developmental biology. Animal 20110601
Hydrogels based on interpenetrating network of chitosan and polyvinyl pyrrolidone for pH-sensitive delivery of repaglinide. Current drug discovery technologies 20110601
A green approach to the synthesis of reduced graphene oxide nanosheets under UV irradiation. Nanotechnology 20110527
Encapsulation of water-soluble drugs by an o/o/o-solvent extraction microencapsulation method. International journal of pharmaceutics 20110516
Enhancing the hydrophilic and antifouling properties of polypropylene nonwoven fabric membranes by the grafting of poly(N-vinyl-2-pyrrolidone) via the ATRP method. Journal of colloid and interface science 20110515
Quantitative analysis of 15N-labeled positional isomers of glutamine and citrulline via electrospray ionization tandem mass spectrometry of their dansyl derivatives. Rapid communications in mass spectrometry : RCM 20110515
Synthesis, in silico docking experiments of new 2-pyrrolidinone derivatives and study of their anti-inflammatory activity. Bioorganic & medicinal chemistry 20110501
Levetiracetam in brain ischemia: clinical implications in neuroprotection and prevention of post-stroke epilepsy. Brain & development 20110401
Effect of surface modification on photoluminescence properties of Y3Al5O12:Ce3+, Gd3+ nano-phosphors. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110401
Fast and facile synthesis of silica coated silver nanoparticles by microwave irradiation. Journal of colloid and interface science 20110315
Effects of polymer wrapping and covalent functionalization on the stability of MWCNT in aqueous dispersions. Journal of colloid and interface science 20110315
Silver and gold icosahedra: one-pot water-based synthesis and their superior performance in the electrocatalysis for oxygen reduction reactions in alkaline media. Chemistry (Weinheim an der Bergstrasse, Germany) 20110314
In vitro antibacterial activity of ceftobiprole against clinical isolates from French teaching hospitals: proposition of zone diameter breakpoints. International journal of antimicrobial agents 20110301
A novel Toxoplasma gondii nuclear factor TgNF3 is a dynamic chromatin-associated component, modulator of nucleolar architecture and parasite virulence. PLoS pathogens 20110301
In vitro antimicrobial effect of the tissue conditioner containing silver nanoparticles. The journal of advanced prosthodontics 20110301
12-oxo-phytodienoic acid accumulation during seed development represses seed germination in Arabidopsis. The Plant cell 20110201
1-[2-(4-Nitrophenyl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetrahydroquinolin-4-yl]pyrrolidin-2-one. Acta crystallographica. Section E, Structure reports online 20110201
Antiarrhythmic and antioxidant activity of novel pyrrolidin-2-one derivatives with adrenolytic properties. Naunyn-Schmiedeberg's archives of pharmacology 20110101
Validated hydrophilic interaction LC-MS/MS method for determination of 2-pyrrolidinone residue: applied to a depletion study of 2-pyrrolidinone in swine liver. Analytical and bioanalytical chemistry 20110101
Short distance movement of genomic negative strands in a host and nonhost for Sugarcane mosaic virus (SCMV). Virology journal 20110101
Preparation of silver nanoparticles in virgin coconut oil using laser ablation. International journal of nanomedicine 20110101
Susceptibility of in vitro produced hatched bovine blastocysts to infection with bluetongue virus serotype 8. Veterinary research 20110101
Electrospun nano composites of poly(vinyl pyrrolidone)/ nano-silver for antibacterial materials. Journal of nanoscience and nanotechnology 20110101
[Studying specific effects of nootropic drugs on glutamate receptors in the rat brain]. Eksperimental'naia i klinicheskaia farmakologiia 20110101
Development and evaluation of controlled porosity osmotic pump for nifedipine and metoprolol combination. Lipids in health and disease 20110101
Inhibition of anaplastic lymphoma kinase (ALK) activity provides a therapeutic approach for CLTC-ALK-positive human diffuse large B cell lymphomas. PloS one 20110101
Synthesis and characterization of silver/montmorillonite/chitosan bionanocomposites by chemical reduction method and their antibacterial activity. International journal of nanomedicine 20110101
1-[2-(4-Nitro-phen-yl)-5-(5-phenyl-1,2-oxazol-3-yl)-1,2,3,4-tetra-hydro-quinolin-4-yl]pyrrolidin-2-one monohydrate. Acta crystallographica. Section E, Structure reports online 20110101
Naphthalene-2,6-dicarb-oxy-lic acid-1-methyl-pyrrolidin-2-one (1/2). Acta crystallographica. Section E, Structure reports online 20110101
Synthesis of silver nanoparticles in montmorillonite and their antibacterial behavior. International journal of nanomedicine 20110101
Antidepressant potential of nitrogen-containing heterocyclic moieties: An updated review. Journal of pharmacy & bioallied sciences 20110101
Iron deposition is independent of cellular inflammation in a cerebral model of multiple sclerosis. BMC neuroscience 20110101
Photo-catalytic activity of Zn1-xMnxS nanocrystals synthesized by wet chemical technique. Nanoscale research letters 20110101
High-energy ball milling technique for ZnO nanoparticles as antibacterial material. International journal of nanomedicine 20110101
Polylactide-co-glycolide nanoparticles for controlled delivery of anticancer agents. International journal of nanomedicine 20110101
Optimization of DNA extraction for RAPD and ISSR analysis of Arbutus unedo L. Leaves. International journal of molecular sciences 20110101
Current state of type 1 diabetes immunotherapy: incremental advances, huge leaps, or more of the same? Clinical & developmental immunology 20110101
Comparative genomics of the mating-type loci of the mushroom Flammulina velutipes reveals widespread synteny and recent inversions. PloS one 20110101
Evaluation of safety margins of Chenopodium album seed decoction: 14-day subacute toxicity and microbicidal activity studies. Reproductive biology and endocrinology : RB&E 20110101
Synthesis, Characterization, Theoretical Crystal Structure, and Antibacterial Activities of Some Transition Metal Complexes of the Thiosemicarbazone (Z)-2-(pyrrolidin-2-ylidene)hydrazinecarbothioamide. Bioinorganic chemistry and applications 20110101
Cell arrest and cell death in mammalian preimplantation development: lessons from the bovine model. PloS one 20110101
Allopregnanolone promotes regeneration and reduces β-amyloid burden in a preclinical model of Alzheimer's disease. PloS one 20110101
Dietary and behavioral interventions protect against age related activation of caspase cascades in the canine brain. PloS one 20110101
Pharmacological screening of Coriandrum sativum Linn. for hepatoprotective activity. Journal of pharmacy & bioallied sciences 20110101
Oxidative stress and leaf senescence. BMC research notes 20110101
Assessing molecular signature for some potential date (Phoenix dactylifera L.) cultivars from Saudi Arabia, based on chloroplast DNA sequences rpoB and psbA-trnH. International journal of molecular sciences 20110101
Anisotropic nanomaterials: structure, growth, assembly, and functions. Nano reviews 20110101
Effect of poly-α, γ, L-glutamic acid as a capping agent on morphology and oxidative stress-dependent toxicity of silver nanoparticles. International journal of nanomedicine 20110101
Protoplast transformation of recalcitrant alkaliphilic Bacillus sp. with methylated plasmid DNA and a developed hard agar regeneration medium. PloS one 20110101
Critical aspects of substrate nanopatterning for the ordered growth of GaN nanocolumns. Nanoscale research letters 20110101
Development and evaluation of novel-trans-buccoadhesive films of Famotidine. Journal of advanced pharmaceutical technology & research 20110101
Investigation of microemulsion system for transdermal delivery of itraconazole. Journal of advanced pharmaceutical technology & research 20110101
Effect of contact lens material on cytotoxicity potential of multipurpose solutions using human corneal epithelial cells. Molecular vision 20110101
Solid dispersions in the form of electrospun core-sheath nanofibers. International journal of nanomedicine 20110101
In vitro Dissolution Studies on Solid Dispersions of Mefenamic Acid. Indian journal of pharmaceutical sciences 20110101
Solubility and dissolution enhancement of etoricoxib by solid dispersion technique using sugar carriers. ISRN pharmaceutics 20110101
Detection and analysis of endogenous badnaviruses in the New Zealand flora. AoB PLANTS 20110101
Preparation and gamma scintigraphic evaluation of colon specific pellets of ketoprofen prepared by powder layering technology. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101
Sustained-release effervescent floating matrix tablets of baclofen: development, optimization and in vitro-in vivo evaluation in healthy human volunteers. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101
Development of diclofenac sodium-loaded alginate-PVP K 30 microbeads using central composite design. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101
Food Restriction-Induced Changes in Gonadotropin-Inhibiting Hormone Cells are Associated with Changes in Sexual Motivation and Food Hoarding, but not Sexual Performance and Food Intake. Frontiers in endocrinology 20110101
Molecular basis for defining the pineal gland and pinealocytes as targets for tumor necrosis factor. Frontiers in endocrinology 20110101
Improvement of solubility and dissolution properties of clotrimazole by solid dispersions and inclusion complexes. Indian journal of pharmaceutical sciences 20110101
In vitro and in vivo evaluation of chitosan buccal films of ondansetron hydrochloride. International journal of pharmaceutical investigation 20110101
Diastereoselective synthesis of (±)-heliotropamide by a one-pot, four-component reaction. The Journal of organic chemistry 20101203
Curcumin-loaded hydrogel nanoparticles: application in anti-malarial therapy and toxicological evaluation. Journal of pharmaceutical sciences 20101201
Microarray analysis of the abscission-related transcriptome in the tomato flower abscission zone in response to auxin depletion. Plant physiology 20101201
(6S,7S,8S,8aS)-6-Ethyl-7,8-dihy-droxy-1,5,6,7,8,8a-hexa-hydro-indolizin-3(2H)-one monohydrate. Acta crystallographica. Section E, Structure reports online 20101201
The removal of heavy metal ions from aqueous solutions by novel pH-sensitive hydrogels. Journal of hazardous materials 20101115
Preparation and evaluation of nicotinic acid sustained-release pellets combined with immediate release simvastatin. International journal of pharmaceutics 20101115
Elucidation of the internal physical and chemical microstructure of pharmaceutical granules using X-ray micro-computed tomography, Raman microscopy and infrared spectroscopy. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20101101
Stereoselective formal synthesis of (+)-allokainic acid via thiol-mediated acyl radical cyclization. Chemical & pharmaceutical bulletin 20101101
Fractionation and identification of organic nitrogen species from bio-oil produced by fast pyrolysis of sewage sludge. Bioresource technology 20101001
Enhancement of the aqueous solubility and masking the bitter taste of famotidine using drug/SBE-beta-CyD/povidone K30 complexation approach. Journal of pharmaceutical sciences 20101001
Formulation of a novel tianeptine sodium orodispersible film. AAPS PharmSciTech 20100901
Investigation of solution and vapor phase mediated phase transformation in thiamine hydrochloride. Journal of pharmaceutical sciences 20100901
Solubilities of crystalline drugs in polymers: an improved analytical method and comparison of solubilities of indomethacin and nifedipine in PVP, PVP/VA, and PVAc. Journal of pharmaceutical sciences 20100901
Proline isosteres in a series of 2,4-disubstituted pyrrolo[1,2-f][1,2,4]triazine inhibitors of IGF-1R kinase and IR kinase. Bioorganic & medicinal chemistry letters 20100901
Pharmacokinetics of a losartan potassium released from a transdermal therapeutic system for the treatment of hypertension. Die Pharmazie 20100901
Simultaneous determination of piracetam and its four impurities by RP-HPLC with UV detection. Journal of chromatographic science 20100801
Analysis and chemistry of migrants from wine fining polymers. Journal of agricultural and food chemistry 20100728
Efficient total synthesis of ammosamide B. Organic letters 20100702
Enantioselective Henry addition of methyl 4-nitrobutyrate to aldehydes. Chiral building blocks for 2-pyrrolidinones and other derivatives. Organic letters 20100702
Concise formal synthesis of (-)-salinosporamide A (marizomib) using a regio- and stereoselective epoxidation and reductive oxirane ring-opening strategy. The Journal of organic chemistry 20100604
Cyto- and genotoxicological assessment and functional characterization of N-vinyl-2-pyrrolidone-acrylic acid-based copolymeric hydrogels with potential for future use in wound healing applications. Biomedical materials (Bristol, England) 20100601
Preparation and evaluation of famotidine polymorphs. Current drug discovery technologies 20100601
(3aR*,6S*,7S*,7aR*)-2-(4-Methoxy-benz-yl)-7-(4-nitro-phen-yl)-6-phenyl-3a,6,7,7a-tetra-hydro-isoindolin-1-one. Acta crystallographica. Section E, Structure reports online 20100601
Influence of polymer content on stabilizing milled amorphous salbutamol sulphate. International journal of pharmaceutics 20100531
Influence of excipients in comilling on mitigating milling-induced amorphization or structural disorder of crystalline pharmaceutical actives. Journal of pharmaceutical sciences 20100501
μ-η:η-Peroxido-bis-[nitratodioxido-bis(pyrrolidin-2-one)uranium(VI)]. Acta crystallographica. Section E, Structure reports online 20100501
Synthesis of spirocyclic carbazole- and acridine-lactams. Organic & biomolecular chemistry 20100421
Total oxidation of toluene on Pt/CeO2-ZrO2-Bi2O3/gamma-Al2O3 catalysts prepared in the presence of polyvinyl pyrrolidone. Journal of hazardous materials 20100415
Platinum-catalyzed intramolecular hydrohydrazination: evidence for alkene insertion into a Pt-N bond. Journal of the American Chemical Society 20100414
Pharmacodynamics of a losartan transdermal system for the treatment of hypertension. Drug development and industrial pharmacy 20100401
Reducing ability and mechanism for polyvinylpyrrolidone (PVP) in silver nanoparticles synthesis. Journal of nanoscience and nanotechnology 20100401
Ethyl 1-benzyl-4-hydr-oxy-2-methyl-5-oxopyrrolidine-3-carboxyl-ate. Acta crystallographica. Section E, Structure reports online 20100401
Interactions at the bilayer interface and receptor site induced by the novel synthetic pyrrolidinone analog MMK3. Biochimica et biophysica acta 20100301
Design, characterization, and evaluation of meloxicam gel prepared by suspension and solution polymerization using solubility parameter as the basis for development. AAPS PharmSciTech 20100301
Effects of thermal curing conditions on drug release from polyvinyl acetate-polyvinyl pyrrolidone matrices. AAPS PharmSciTech 20100301
Buccal drug delivery of pravastatin sodium. AAPS PharmSciTech 20100301
Polymer blends used to prepare nifedipine loaded hollow microspheres for a floating-type oral drug delivery system: in vitro evaluation. Archives of pharmacal research 20100301
Molecular genetic tools to infer the origin of forest plants and wood. Applied microbiology and biotechnology 20100201
BIN1 localizes the L-type calcium channel to cardiac T-tubules. PLoS biology 20100201
Polymer-drug interactions and wetting of solid dispersions. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100131
Influence of temperature on the solubilization of thiabendazole by combined action of solid dispersions and co-solvents. International journal of pharmaceutics 20100115
Brivaracetam (ucb 34714) inhibits Na(+) current in rat cortical neurons in culture. Epilepsy research 20100101
Single-walled carbon nanotubes dispersed in aqueous media via non-covalent functionalization: effect of dispersant on the stability, cytotoxicity, and epigenetic toxicity of nanotube suspensions. Water research 20100101
Role of platelets in neuroinflammation: a wide-angle perspective. Journal of neuroinflammation 20100101
Chemistry of secondary polyphenols produced during processing of tea and selected foods. International journal of molecular sciences 20100101
SSHscreen and SSHdb, generic software for microarray based gene discovery: application to the stress response in cowpea. Plant methods 20100101
Synthesis and pharmacological evaluation of pyrrolidin-2-one derivatives as antiarrhythmic, antihypertensive and alpha-adrenolytic agents. Pharmacological reports : PR 20100101
[Post-operative bacteremia caused by multidrug-resistant Aerococcus viridans in a patient with gall bladder cancer]. Mikrobiyoloji bulteni 20100101
Generating a generation of proteasome inhibitors: from microbial fermentation to total synthesis of salinosporamide a (marizomib) and other salinosporamides. Marine drugs 20100101
A review on progress in QSPR studies for surfactants. International journal of molecular sciences 20100101
A preliminary study of reactive oxygen species activity within motile Boer buck sperm using confocal laser scanning microscope (CLSM). La Clinica terapeutica 20100101
Tetramic and tetronic acids as scaffolds in bioinorganic and bioorganic chemistry. Bioinorganic chemistry and applications 20100101
Prevalence of Plasmodium vivax VK210 and VK247 subtype in Myanmar. Malaria journal 20100101
Hall measurements on carbon nanotube paper modified with electroless deposited platinum. Nanoscale research letters 20100101
Well-aligned Nickel Nanochains Synthesized by a Template-free Route. Nanoscale research letters 20100101
Engineering of N. benthamiana L. plants for production of N-acetylgalactosamine-glycosylated proteins--towards development of a plant-based platform for production of protein therapeutics with mucin type O-glycosylation. BMC biotechnology 20100101
Novel rare earth-polyvinyl pyridine complex functionalized hybrid silica microspheres: molecular assembly and photophysical property. Photochemistry and photobiology 20100101
ETM-ANN approach application for thiobenzamide and quinolizidine derivatives. Journal of biomedicine & biotechnology 20100101
Antiarrhythmic activity of novel S-enantiomers of pyrrolidin-2-one derivatives with adrenolytic properties. Acta poloniae pharmaceutica 20100101
Fast Dissolving Sublingual Films of Ondansetron Hydrochloride: Effect of Additives on in vitro Drug Release and Mucosal Permeation. Journal of young pharmacists : JYP 20100101
[Further improvement of the methods for the arrest of nasal bleeding]. Vestnik otorinolaringologii 20100101
Green synthesis of silver/montmorillonite/chitosan bionanocomposites using the UV irradiation method and evaluation of antibacterial activity. International journal of nanomedicine 20100101
Engineering the chloroplast targeted malarial vaccine antigens in Chlamydomonas starch granules. PloS one 20100101
Transdermal drug delivery of labetalol hydrochloride: Feasibility and effect of penetration enhancers. Journal of pharmacy & bioallied sciences 20100101
Development of a floating dosage form of ranitidine hydrochloride by statistical optimization technique. Journal of young pharmacists : JYP 20100101
Methyl 7,8-diacet-oxy-11-oxo-5-(2-oxo-pyrrolidin-1-yl)-7,9-epoxy-cyclo-penta-[4,5]pyrido[1,2-a]quinoline-10-carboxyl-ate sesquihydrate. Acta crystallographica. Section E, Structure reports online 20100101
In vitro response of retinal pigment epithelial cells exposed to chitosan materials prepared with different cross-linkers. International journal of molecular sciences 20100101
Infective Endocarditis: Identification of Catalase-Negative, Gram-Positive Cocci from Blood Cultures by Partial 16S rRNA Gene Analysis and by Vitek 2 Examination. The open microbiology journal 20100101
Preparation of Aligned Ultra-long and Diameter-controlled Silicon Oxide Nanotubes by Plasma Enhanced Chemical Vapor Deposition Using Electrospun PVP Nanofiber Template. Nanoscale research letters 20100101
Formulation and evaluation of trimetazidine dihydrochloride extended release tablets by melt congealing method. Indian journal of pharmaceutical sciences 20100101
Effect of Different Carriers on in vitro Permeation of Meloxicam through Rat Skin. Indian journal of pharmaceutical sciences 20100101
Iron oxide-based nanomagnets in nanomedicine: fabrication and applications. Nano reviews 20100101
The effect of pectin on swelling and permeability characteristics of free films containing Eudragit RL and/or RS as a coating formulation aimed for colonic drug delivery. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101
Preparation and in-vitro evaluation of indomethacin nanoparticles. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101
Cobalt-catalyzed regioselective synthesis of pyrrolidinone derivatives by reductive coupling of nitriles and acrylamides. Journal of the American Chemical Society 20091230
Selective light emission in nonbonding electron transitions in poly(vinyl pyrrolidone) molecules on spin-coating in thin layers. The journal of physical chemistry. A 20091224
Design of a 24-hour controlled porosity osmotic pump system containing PVP: formulation variables. Drug development and industrial pharmacy 20091201
trans-Bis(1-cyclo-hexyl-pyrrolidin-2-one)dinitratopalladium(II). Acta crystallographica. Section E, Structure reports online 20091201
Current and Novel Inhibitors of HIV Protease. Viruses 20091201
Zinc supplementation improves the outcome of chronic hepatitis C and liver cirrhosis. Journal of clinical biochemistry and nutrition 20091101
6-Benzyl-3-(1,4-dioxaspiro-[4.5]decan-2-yl)-8,8-dimethyl-1-oxa-2,6-diaza-spiro-[4.4]non-2-ene-7,9-dione. Acta crystallographica. Section E, Structure reports online 20091101
Nitro-Mannich/lactamization cascades for the direct stereoselective synthesis of pyrrolidin-2-ones. Organic letters 20091015
Translational and rotational diffusion of a small globular protein under crowded conditions. The journal of physical chemistry. B 20091008
Design, synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxy-propyl]-3,3-diphenylpyrrolidin-2-one derivatives with antiarrhythmic, antihypertensive, and alpha-adrenolytic activity. European journal of medicinal chemistry 20091001
Rubisco in planta kcat is regulated in balance with photosynthetic electron transport. Journal of experimental botany 20091001
Thermally induced dissociation nature of pure 2-pyrrolidinone via near-infrared correlation spectroscopy analysis. Applied spectroscopy 20091001
Application of simplex lattice design and desirability function for the formulation development of mouth dissolving film of salbutamol sulphate. Current drug delivery 20091001
1,3,5-Tris(N-phenyl-benzimidazol-2-yl)benzene methanol solvate. Acta crystallographica. Section E, Structure reports online 20091001
Development and optimization of a sublingual tablet formulation for physostigmine salicylate. Acta pharmaceutica (Zagreb, Croatia) 20090901
[Regioselectivity in the dehydrogenation of substituted ethylenediamines as nicotine models]. Die Pharmazie 20090901
Metadoxine, an ion-pair of pyridoxine and L-2-pyrrolidone-5-carboxylate, blocks adipocyte differentiation in association with inhibition of the PKA-CREB pathway. Archives of biochemistry and biophysics 20090815
Grafting modification and structural degradation of multi-walled carbon nanotubes under the effect of ultrasonics sonochemistry. Ultrasonics sonochemistry 20090801
(3aR,8aS,9S,9aR)-9-Hydroxy-perhydro-furo[3,2-f]indolizin-6-one. Acta crystallographica. Section E, Structure reports online 20090801
A one-pot method to enhance dissolution rate of low solubility drug molecules using dispersion polymerization in supercritical carbon dioxide. International journal of pharmaceutics 20090730
Double-layer weekly sustained release transdermal patch containing gestodene and ethinylestradiol. International journal of pharmaceutics 20090730
Microwave assisted synthesis of unsaturated jasmone heterocyclic analogues as new fragrant substances. European journal of medicinal chemistry 20090701
Profile of the new pyrrolidone derivative seletracetam (ucb 44212) in animal models of epilepsy. European journal of pharmacology 20090701
SAM levels, gene expression of SAM synthetase, methionine synthase and ACC oxidase, and ethylene emission from N. suaveolens flowers. Plant molecular biology 20090701
Chemical penetration enhancers: a patent review. Expert opinion on therapeutic patents 20090701
Optical properties in nanofluids of gold nanoparticles in poly(vinylpyrrolidone). Journal of nanoscience and nanotechnology 20090701
Phase behavior of mixtures of positively charged colloidal platelets and nonadsorbing polymer. Langmuir : the ACS journal of surfaces and colloids 20090602
Improvement of cytocompatibility of electrospinning PLLA microfibers by blending PVP. Journal of materials science. Materials in medicine 20090601
A novel hydrophilic adhesive matrix with self-enhancement for drug percutaneous permeation through rat skin. Pharmaceutical research 20090601
Cefuroxime axetil solid dispersion with polyglycolized glycerides for improved stability and bioavailability. The Journal of pharmacy and pharmacology 20090601
[Study on chemical constituents from roots of Saussurea lappa]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090501
Vitamin B12 diffusion and binding in crosslinked poly(acrylic acid)s and poly(acrylic acid-co-N-vinyl pyrrolidinone)s. International journal of pharmaceutics 20090417
Preparation and in vitro evaluation of a new fentanyl patch based on acrylic/silicone pressure-sensitive adhesive blends. Drug development and industrial pharmacy 20090401
(8aS)-7,8,8a,9-Tetra-hydro-thieno[3,2-f]indolizin-6(4H)-one. Acta crystallographica. Section E, Structure reports online 20090401
Plasticizers in the manufacture of novel skin-bioadhesive patches. International journal of pharmaceutics 20090331
Anti-inflammatory activity and PGE2 inhibitory properties of novel phenylcarbamoylmethyl ester-containing compounds. Molecules (Basel, Switzerland) 20090211
Pesticidal seed coats based on azadirachtin-A: release kinetics, storage life and performance. Pest management science 20090201
Formulation and evaluation of in situ gelling thermoreversible mucoadhesive gel of fluconazole. Drug discoveries & therapeutics 20090201
Mechanistic studies on the copper-catalyzed N-arylation of amides. Journal of the American Chemical Society 20090114
Effect of PVP K30 and/or L-arginine on stability constant of etoricoxib-HPbetaCD inclusion complex: preparation and characterization of etoricoxib-HPbetaCD binary system. Drug development and industrial pharmacy 20090101
Quantification of fibronectin 1 (FN1) splice variants, including two novel ones, and analysis of integrins as candidate FN1 receptors in bovine preimplantation embryos. BMC developmental biology 20090101
Simple high-cell density fed-batch technique for high-level recombinant protein production with Pichia pastoris: Application to intracellular production of Hepatitis B surface antigen. Microbial cell factories 20090101
Approaches to polymer selection for mascara formulation. Journal of cosmetic science 20090101
Vancomycin resistant enterococci (VRE) in Swedish sewage sludge. Acta veterinaria Scandinavica 20090101
Gold nanoparticles induce cytotoxicity in the alveolar type-II cell lines A549 and NCIH441. Particle and fibre toxicology 20090101
Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures. Neuropsychiatric disease and treatment 20090101
Genome-wide analysis reveals rapid and dynamic changes in miRNA and siRNA sequence and expression during ovule and fiber development in allotetraploid cotton (Gossypium hirsutum L.). Genome biology 20090101
Phenylalanine-rich peptides potently bind ESAT6, a virulence determinant of Mycobacterium tuberculosis, and concurrently affect the pathogen's growth. PloS one 20090101
Alfuzosin hydrochloride transdermal films: evaluation of physicochemical, in vitro human cadaver skin permeation and thermodynamic parameters. International braz j urol : official journal of the Brazilian Society of Urology 20090101
Carvedilol-loaded mucoadhesive buccal tablets: influence of various mucoadhesive polymers on drug release behavior. PDA journal of pharmaceutical science and technology 20090101
Development and evaluation of nefopam transdermal matrix patch system in human volunteers. PDA journal of pharmaceutical science and technology 20090101
In vitro production of buffalo embryos from stepwise vitrified immature oocytes. Veterinaria italiana 20090101
In situ forming polymeric drug delivery systems. Indian journal of pharmaceutical sciences 20090101
Enhanced Luminescence of Eu-Doped TiO2Nanodots. Nanoscale research letters 20090101
Gram-negative bacterial sensors for eukaryotic signal molecules. Sensors (Basel, Switzerland) 20090101
Brivaracetam and seletracetam, two new SV2A ligands, improve paroxysmal dystonia in the dt sz mutant hamster. European journal of pharmacology 20081228
Protein conformation in amorphous solids by FTIR and by hydrogen/deuterium exchange with mass spectrometry. Biophysical journal 20081215
Analysis of several methods for the extraction of high quality DNA from acetic acid bacteria in wine and vinegar for characterization by PCR-based methods. International journal of food microbiology 20081210
Characterization of ternary complexes of meloxicam-HPbetaCD and PVP or L-arginine prepared by the spray-drying technique. Acta pharmaceutica (Zagreb, Croatia) 20081201
Treatment of Lennox-Gastaut syndrome: overview and recent findings. Neuropsychiatric disease and treatment 20081201
Preparation and characterization of electrospun silica nanofibers from PVP/P123 blended polymer solution. Journal of nanoscience and nanotechnology 20081001
HPLC analysis, isolation and identification of a new degradation product in carvedilol tablets. Journal of pharmaceutical and biomedical analysis 20080910
Biphasic hydrogenation over PVP stabilized Rh nanoparticles in hydroxyl functionalized ionic liquids. Inorganic chemistry 20080901
Localization of sucrose synthase in developing seed and siliques of Arabidopsis thaliana reveals diverse roles for SUS during development. Journal of experimental botany 20080901
Electron capture dissociation, electron detachment dissociation, and collision-induced dissociation of polyamidoamine (PAMAM) dendrimer ions with amino, amidoethanol, and sodium carboxylate surface groups. Journal of the American Society for Mass Spectrometry 20080901
Mucoadhesive bilayered patches for administration of sumatriptan succinate. AAPS PharmSciTech 20080901
Development and in-vitro evaluation of transdermal matrix films of metoprolol tartrate. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080901
Thioesterase-like role for fungal PKS-NRPS hybrid reductive domains. Journal of the American Chemical Society 20080820
Surfactant-mediated growth of nanostructured zinc oxide thin films via electrodeposition and their photoelectrochemical performance. Nanotechnology 20080813
A concise and straightforward total synthesis of (+/-)-salinosporamide A, based on a biosynthesis model. Organic & biomolecular chemistry 20080807
The interaction of gabapentin and N6-(2-phenylisopropyl)-adenosine R-(-)isomer (R-PIA) on mechanical allodynia in rats with a spinal nerve ligation. Journal of Korean medical science 20080801
Structure formation and characterization of injectable drug loaded biodegradable devices: in situ implants versus in situ microparticles. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080703
Protein engineering strategies for sustained glucagon-like peptide-1 receptor-dependent control of glucose homeostasis. Diabetes 20080701
Process and formulation characterizations of the thermal adhesion granulation (TAG) process for improving granular properties. International journal of pharmaceutics 20080605
Sumatriptan succinate transdermal delivery systems for the treatment of migraine. Journal of pharmaceutical sciences 20080601
A study on maize proteins as a potential new tablet excipient. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080601
Synthesis and characterization of pectin/PVP hydrogel membranes for drug delivery system. AAPS PharmSciTech 20080601
Ceftobiprole: an extended-spectrum anti-methicillin-resistant Staphylococcus aureus cephalosporin. The Annals of pharmacotherapy 20080601
(11R,11aS)-11-Hydr-oxy-1,5,11,11a-tetra-hydro-1-benzothieno[2,3-f]indolizin-3(2H)-one. Acta crystallographica. Section E, Structure reports online 20080601
Benzyl 2-cyano-3,3-dimethyl-1-pyrrolidinecarboxylate, a versatile intermediate for the synthesis of 3,3-dimethylproline derivatives. The Journal of organic chemistry 20080516
Arsenic adsorption by polyvinyl pyrrolidone K25 coated cassava peel carbon from aqueous solution. Journal of hazardous materials 20080501
Evaluation of the enthalpy of formation, proton affinity, and gas-phase basicity of gamma-butyrolactone and 2-pyrrolidinone by isodesmic reactions. The journal of physical chemistry. A 20080501
Stereochemistry of flavonoidal alkaloids from Dracocephalum rupestre. Phytochemistry 20080401
Application of mass spectrometry for the detection of glycation and oxidation products in milk proteins. Annals of the New York Academy of Sciences 20080401
tert-Butyl 5-(4-methoxy-phen-yl)-1-methyl-2-oxopyrrolidin-3-yl carbonate. Acta crystallographica. Section E, Structure reports online 20080401
Generation of superoxide anion in chloroplasts of Arabidopsis thaliana during active photosynthesis: a focus on rapidly induced genes. Plant molecular biology 20080301
In vitro activity profile of ceftobiprole, an anti-MRSA cephalosporin, against recent gram-positive and gram-negative isolates of European origin. The Journal of antimicrobial chemotherapy 20080301
Effect of internal lubricating agents of disposable soft contact lenses on higher-order aberrations after blinking. Eye & contact lens 20080301
Percutaneous permeation enhancement by terpenes: mechanistic view. The AAPS journal 20080301
Preparation and characterization of electrospun SiO2 nanofibers. Journal of nanoscience and nanotechnology 20080301
Nano-vectors for efficient liver specific gene transfer. International journal of nanomedicine 20080301
4-Hydr-oxy-5-(4-methoxy-phen-yl)pyrrolidin-2-one. Acta crystallographica. Section E, Structure reports online 20080301
Zero-order delivery of a highly soluble, low dose drug alfuzosin hydrochloride via gastro-retentive system. International journal of pharmaceutics 20080204
Solubility-modulated monolithic osmotic pump tablet for atenolol delivery. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20080201
3-Aminopyrrolidines from alpha-aminoacids: total synthesis of (+)-nemonapride from D-alanine. The Journal of organic chemistry 20080201
Role of additives like polymers and surfactants in the crystallization of mebendazole. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20080201
Monotherapy for partial epilepsy: focus on levetiracetam. Neuropsychiatric disease and treatment 20080201
1-Benzyl-6-phenyl-imino-5-(pyrrol-2-yl-idene)hexa-hydro-pyrimidine-2,4-dione. Acta crystallographica. Section E, Structure reports online 20080201
Cardiovascular effects of transdermally delivered bupranolol in rabbits: effect of chemical penetration enhancers. Life sciences 20080130
Synthesis and evaluation of a gamma-lactam as a highly selective EP2 and EP4 receptor agonist. Bioorganic & medicinal chemistry letters 20080115
Development of monoclonal antibodies for the fusarin mycotoxins. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20080101
Regulation of DNA synthesis and the cell cycle in human prostate cancer cells and lymphocytes by ovine uterine serpin. BMC cell biology 20080101
Identification and characterization of a novel Plasmodium falciparum merozoite apical protein involved in erythrocyte binding and invasion. PloS one 20080101
Antibacterial and antimycotic activity of a cross-linked electrospun poly(vinyl pyrrolidone)-iodine complex and a poly(ethylene oxide)/poly(vinyl pyrrolidone)-iodine complex. Journal of biomaterials science. Polymer edition 20080101
Sperm-derived histones contribute to zygotic chromatin in humans. BMC developmental biology 20080101
Management of contaminated autologous grafts in plastic surgery. Eplasty 20080101
The Arabidopsis thaliana response regulator ARR22 is a putative AHP phospho-histidine phosphatase expressed in the chalaza of developing seeds. BMC plant biology 20080101
One-pot parallel solution-phase synthesis of 1-substituted 4-(2-aminoethyl)-1H-pyrazol-5-ols. Journal of combinatorial chemistry 20080101
Ruthenium-catalyzed carbonylative cycloaddition reactions involving carbonyl and imino groups as assembling units. Chemical record (New York, N.Y.) 20080101
Rapid and high quality DNA isolation from Origanum onites for RAPD and ISSR analysis. Zeitschrift fur Naturforschung. C, Journal of biosciences 20080101
Proteomic analysis of protein deposits on worn daily wear silicone hydrogel contact lenses. Molecular vision 20080101
Abstracts of papers presented at the 2008 pittsburgh conference. Journal of automated methods & management in chemistry 20080101
Modifications of antiepileptic drugs for improved tolerability and efficacy. Perspectives in medicinal chemistry 20080101
Design and development of mixed film of pectin: ethyl cellulose for colon specific drug delivery of sennosides and triphala. Indian journal of pharmaceutical sciences 20080101
Optimization of fast dissolving etoricoxib tablets prepared by sublimation technique. Indian journal of pharmaceutical sciences 20080101
Flow of Formulation Granules through a Conical Hopper. Indian journal of pharmaceutical sciences 20080101
Treatment of myoclonic seizures in patients with juvenile myoclonic epilepsy. Neuropsychiatric disease and treatment 20071201
Mixed transition metal-lanthanide complexes at high oxidation states: heteronuclear CeIVMnIV clusters. Inorganic chemistry 20071112
Complementary stereocontrolled approaches to 2-pyrrolidinones bearing a vicinal amino diol subunit with three continuous chiral centers: a formal asymmetric synthesis of (-)-detoxinine. The Journal of organic chemistry 20071109
Pyrrolidinone-modified di- and tripeptides: highly diastereoselective preparation and investigation of their stability. Organic & biomolecular chemistry 20071107
Biosynthesis of violacein: a genuine intermediate, protoviolaceinic acid, produced by VioABDE, and insight into VioC function. Chemical communications (Cambridge, England) 20071028
A practical synthesis of (3R,4R)-N-tert-butoxycarbonyl-4-hydroxymethylpyrrolidin-3-ol. Organic & biomolecular chemistry 20070907
Solubilization of poorly soluble compounds using 2-pyrrolidone. International journal of pharmaceutics 20070905
Quantitative phosphoproteomic analysis of plasma membrane proteins reveals regulatory mechanisms of plant innate immune responses. The Plant journal : for cell and molecular biology 20070901
Synthesis and pharmacological evaluation of new 1-[3-(4-arylpiperazin-1-yl)-2-hydroxypropyl]-pyrrolidin-2-one derivatives with anti-arrhythmic, hypotensive, and alpha-adrenolytic activity. Archiv der Pharmazie 20070901
An open trial of levetiracetam for segmental and generalized dystonia. Movement disorders : official journal of the Movement Disorder Society 20070815
Effect of pore former on the properties of casted film prepared from blends of Eudragit NE 30 D and Eudragit L 30 D-55. Chemical & pharmaceutical bulletin 20070801
Site-specific formation of Maillard, oxidation, and condensation products from whey proteins during reaction with lactose. Journal of agricultural and food chemistry 20070725
Preparation of magnetite nanocrystals with surface reactive moieties by one-pot reaction. Journal of colloid and interface science 20070715
Effect of hydrophilic polymers on buccoadhesive Eudragit patches of propranolol hydrochloride using factorial design. AAPS PharmSciTech 20070622
Modulation of drug release kinetics from hydroxypropyl methyl cellulose matrix tablets using polyvinyl pyrrolidone. International journal of pharmaceutics 20070607
Monitoring of dissolution induced changes in film coat composition by 1H NMR spectroscopy and SEM. Journal of controlled release : official journal of the Controlled Release Society 20070604
Biomass in the manufacture of industrial products--the use of proteins and amino acids. Applied microbiology and biotechnology 20070601
A beta-keto ester as a novel, efficient, and versatile ligand for copper(I)-catalyzed C-N, C-O, and C-S coupling reactions. The Journal of organic chemistry 20070511
Synthesis and stabilization of Prussian blue nanoparticles and application for sensors. Journal of colloid and interface science 20070501
Development of photolabile caged analogs of endothelin-1. Peptides 20070501
Problems of positive list system revealed by survey of pesticide residue in food. The Journal of toxicological sciences 20070501
Novel synthons from mucochloric acid: the first use of alpha,beta-dichloro-gamma-butenolides and gamma-butyrolactams for direct vinylogous aldol addition. The Journal of organic chemistry 20070427
Determination of N-vinyl-2-pyrrolidone and N-methyl-2-pyrrolidone in drugs using polypyrrole-based headspace solid-phase microextraction and gas chromatography-nitrogen-phosphorous detection. Analytica chimica acta 20070321
Organocatalytic sequential alpha-amination-Horner-Wadsworth-Emmons olefination of aldehydes: enantioselective synthesis of gamma-amino-alpha,beta-unsaturated esters. Organic letters 20070315
A novel in situ forming drug delivery system for controlled parenteral drug delivery. International journal of pharmaceutics 20070306
Dip-pen lithography using pens of different thicknesses. Journal of nanoscience and nanotechnology 20070301
Surface enhanced optical absorption and photoluminescence in nonbonding electrons in small poly(vinylpyrrolidone) molecules. The Journal of chemical physics 20070227
Intramolecular PIFA-mediated alkyne amidation and carboxylation reaction. The Journal of organic chemistry 20070216
Controlled synthesis and association behavior of graft Pluronic in aqueous solutions. Journal of colloid and interface science 20070215
Diffusion and structure of water in polymers containing N-vinyl-2-pyrrolidone. The journal of physical chemistry. B 20070208
Synthesis of the pyrrolidinone core of KSM-2690 B. Organic letters 20070201
Preparation and in vitro evaluation of ethyl cellulose microspheres containing stavudine by the double emulsion method. Die Pharmazie 20070201
Design and in vitro testing of a floatable gastroretentive tablet of metformin hydrochloride. Die Pharmazie 20070201
Purification and characterization of alcohol dehydrogenase reducing N-benzyl-3-pyrrolidinone from Geotrichum capitatum. Journal of bioscience and bioengineering 20070201
Dehydration versus deamination of N-terminal glutamine in collision-induced dissociation of protonated peptides. Journal of the American Society for Mass Spectrometry 20070101
Seletracetam (UCB 44212). Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20070101
Biocompatibility of nanocomposites used for artificial conjunctiva: in vivo experiments. Current eye research 20070101
Polymeric nanoparticle-encapsulated curcumin ('nanocurcumin'): a novel strategy for human cancer therapy. Journal of nanobiotechnology 20070101
Intracellular sugars improve survival of human red blood cells cryopreserved at -80 degrees C in the presence of polyvinyl pyrrolidone and human serum albumin. Cryo letters 20070101
Physiological evaluation of the filamentous fungus Trichoderma reesei in production processes by marker gene expression analysis. BMC biotechnology 20070101
Identification and expression analysis of genes associated with bovine blastocyst formation. BMC developmental biology 20070101
Monitoring of transcriptional regulation in Pichia pastoris under protein production conditions. BMC genomics 20070101
Gastrointestinal permeability in ovarian cancer and breast cancer patients treated with paclitaxel and platinum. BMC cancer 20070101
Efficacy of two ethanol-based skin antiseptics on the forehead at shorter application times. BMC microbiology 20070101
A convenient allylsilane-N-acyliminium route toward indolizidine and quinolizidine alkaloids. Beilstein journal of organic chemistry 20070101
Induced prion protein controls immune-activated retroviruses in the mouse spleen. PloS one 20070101
Patented small molecule inhibitors in the ubiquitin proteasome system. BMC biochemistry 20070101
Single-cell duplex RT-LATE-PCR reveals Oct4 and Xist RNA gradients in 8-cell embryos. BMC biotechnology 20070101
Delayed functional expression of neuronal chemokine receptors following focal nerve demyelination in the rat: a mechanism for the development of chronic sensitization of peripheral nociceptors. Molecular pain 20070101
Superparamagnetic iron oxide nanoparticles coated with galactose-carrying polymer for hepatocyte targeting. Journal of biomedicine & biotechnology 20070101
Synthesis and structural characterisation as 12-helix of the hexamer of a beta-amino acid tethered to a pyrrolidin-2-one ring. Chemical communications (Cambridge, England) 20061221
Probing the interaction of poly(vinylpyrrolidone) with platinum nanocrystals by UV-Raman and FTIR. The journal of physical chemistry. B 20061123
Discovery of orally active butyrolactam 11beta-HSD1 inhibitors. Bioorganic & medicinal chemistry letters 20061101
Stability of poly(D,L-lactide-co-glycolide) and leuprolide acetate in in-situ forming drug delivery systems. Journal of controlled release : official journal of the Controlled Release Society 20061010
Poly(vinyl pyrrolidone): a dual functional reductant and stabilizer for the facile synthesis of noble metal nanoplates in aqueous solutions. Langmuir : the ACS journal of surfaces and colloids 20060926
Primary explosives: electrostatic discharge initiation, additive effect and its relation to thermal and explosive characteristics. Journal of hazardous materials 20060921
The influence of PVP incorporation on moisture-induced surface crystallization of amorphous spray-dried lactose particles. International journal of pharmaceutics 20060914
Vacuum foam drying for preservation of LaSota virus: effect of additives. AAPS PharmSciTech 20060901
Enhancement of dissolution profile by solid dispersion (kneading) technique. AAPS PharmSciTech 20060901
A highly efficient synthesis of potent and selective butyrolactam inhibitors of 11beta-HSD1. Organic letters 20060831
A concise total synthesis of salinosporamide A. Organic & biomolecular chemistry 20060807
Thiourea-catalyzed asymmetric michael addition of activated methylene compounds to alpha,beta-unsaturated imides: dual activation of imide by intra- and intermolecular hydrogen bonding. Journal of the American Chemical Society 20060726
Molecular dynamics and interactions of aqueous and dichloromethane solutions of polyvinylpyrrolidone. The Journal of chemical physics 20060721
Bioadhesive monolayer film for the in vitro transdermal delivery of sumatriptan. Journal of pharmaceutical sciences 20060701
Formulation and optimization of mouth dissolve tablets containing rofecoxib solid dispersion. AAPS PharmSciTech 20060601
Selective placement of templated DNA nanowires between microstructured electrodes. International journal of nanomedicine 20060601
Microwave assisted synthesis of fragrant jasmone heterocyclic analogues. European journal of medicinal chemistry 20060501
Levels of N-methyl-2-pyrrolidone (NMP) and its metabolites in plasma and urine from volunteers after experimental exposure to NMP in dry and humid air. Toxicology letters 20060410
Preparation and characterization of (PVP + NaClO4) electrolytes for battery applications. The European physical journal. E, Soft matter 20060401
Synthesis and characterization of pyrrolidin-2-one fused N-confused calix[4]phyrins. Organic letters 20060316
Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds. European journal of medicinal chemistry 20060301
Effect of N-1 and N-2 residues on peptide deamidation rate in solution and solid state. The AAPS journal 20060301
Formulation of tablets from the crude extract of Rhinacanthus nasutus (Thai local plant) against Aedes aegypti and Culex quinquefasciatus larvae: a preliminary study. The Southeast Asian journal of tropical medicine and public health 20060301
Reducing-difference infrared spectral analysis of cis- and trans-configurated lactams. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060201
Stability and degradation profiles of Spantide II in aqueous solutions. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060201
Dissolution rate improvement of poorly water-soluble drugs obtained by adsorbing solutions of drugs in hydrophilic solvents onto high surface area carriers. European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060201
Epidemiology of Streptococcus agalactiae colonization in Germany. International journal of medical microbiology : IJMM 20060201
Molecular mobility of nifedipine-PVP and phenobarbital-PVP solid dispersions as measured by 13C-NMR spin-lattice relaxation time. Journal of pharmaceutical sciences 20060201
In situ gelling, bioadhesive nasal inserts for extended drug delivery: in vitro characterization of a new nasal dosage form. European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060101
A new water-based topical carrier with polar skin-lipids. Lipids in health and disease 20060101
[Correlations of pharmacokinetics and pharmacodynamics of a combined preparation containing pyrrolidone and pyroglutamic acid]. Eksperimental'naia i klinicheskaia farmakologiia 20060101
Cell growth on tissue-engineering scaffolds prepared by gamma irradiation grafting of N-vinyl-2-pyrrolidone onto polyvinyl alcohol. Journal of biomaterials science. Polymer edition 20060101
[Promoters of genes MTHFR from patients with hyperhomocysteinemia and PTEN from patients with malignant and benign endometrial and ovarian tumors]. Bioorganicheskaia khimiia 20060101
Ceftobiprole Medocaril: BAL5788, JNJ 30982081, JNJ30982081, RO 65-5788, RO 655788. Drugs in R&D 20060101
Transcriptional monitoring of steady state and effects of anaerobic phases in chemostat cultures of the filamentous fungus Trichoderma reesei. BMC genomics 20060101
Transcriptional and post-transcriptional regulation of retrotransposons IAP and MuERV-L affect pluripotency of mice ES cells. Reproductive biology and endocrinology : RB&E 20060101
Identification of prevalent potyvirus on maize and johnsongrass in corn fields of Tehran province of Iran and a study on some of its properties. Communications in agricultural and applied biological sciences 20060101
Nitrenium ion azaspirocyclization-spirodienone cleavage: a new synthetic strategy for the stereocontrolled preparation of highly substituted lactams and N-hydroxy lactams. The Journal of organic chemistry 20051209
DFT study of the monomers and dimers of 2-pyrrolidone: equilibrium structures, vibrational, orbital, topological, and NBO analysis of hydrogen-bonded interactions. The journal of physical chemistry. A 20051208
Making succinate more successful. Environmental health perspectives 20051201
Electrophilic activation of lactams with Tf2O and pyridine: expedient synthesis of (+/-)-tetraponerine T4. Organic letters 20051124
Intrinsic adhesion properties of poly(vinyl pyrrolidone) to pharmaceutical materials: humidity effect. Macromolecular bioscience 20051104
Investigation of physicochemical properties of lactam-based Brønsted acidic ionic liquids. The journal of physical chemistry. B 20051020
Effect of bioactive compounds from Sainfoin ( Onobrychis viciifolia Scop.) on the in vitro larval migration of Haemonchus contortus: role of tannins and flavonol glycosides. Parasitology 20051001
Stabilizer choice for rapid dissolving high potency itraconazole particles formed by evaporative precipitation into aqueous solution. International journal of pharmaceutics 20050930
Development of two enzyme-linked immunosorbent assays for detection of endosulfan residues in agricultural products. Journal of agricultural and food chemistry 20050921
Preparation and Suzuki-Miyaura coupling reactions of tetrahydropyridine-2-boronic acid pinacol esters. The Journal of organic chemistry 20050902
Concentrations of N-methyl-2-pyrrolidone (NMP) and its metabolites in plasma and urine following oral administration of NMP to rats. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20050901
Ocular inserts for controlled delivery of pefloxacin mesylate: preparation and evaluation. Acta pharmaceutica (Zagreb, Croatia) 20050901
Stereoselective synthesis of constrained azacyclic hydroxyethylene isosteres as aspartic protease inhibitors: dipolar cycloaddition and related methodologies toward branched pyrrolidine and pyrrolidinone carboxylic acids. The Journal of organic chemistry 20050819
Structure-based design, synthesis, and memapsin 2 (BACE) inhibitory activity of carbocyclic and heterocyclic peptidomimetics. Journal of medicinal chemistry 20050811
Synthesis of fluorescent silica-coated gibbsite platelets. Journal of colloid and interface science 20050715
Toward improving the chemistry of N-acyliminium ions: nucleophilic substitution reactions of pyrrolidinone derivatives with trialkylsilyl nucleophiles catalyzed by triisopropylsilyltrifluoromethane sulfonate (TIPSOTf). Organic letters 20050707
Lead exposure inhibits fracture healing and is associated with increased chondrogenesis, delay in cartilage mineralization, and a decrease in osteoprogenitor frequency. Environmental health perspectives 20050601
Blockade of nuclear factor-kappaB activation prevents hypodynamic shock and gastric hypoperfusion induced by endotoxin in anesthetized dogs. Intensive care medicine 20050501
Preclinical evaluation of the pharmacodynamic properties of 2,5-diaziridinyl-3-hydroxymethyl-6-methyl-1,4-benzoquinone. Clinical cancer research : an official journal of the American Association for Cancer Research 20050401
The synthesis of (-)-isodomoic acid C. Journal of the American Chemical Society 20050302
Effects of acidic N + 1 residues on asparagine deamidation rates in solution and in the solid state. Journal of pharmaceutical sciences 20050301
Skin permeation of propranolol from polymeric film containing terpene enhancers for transdermal use. International journal of pharmaceutics 20050131
Effect of penetration enhancers on the release and skin permeation of bupranolol from reservoir-type transdermal delivery systems. International journal of pharmaceutics 20050120
CCR5 antagonists as anti-HIV-1 agents. Part 3: Synthesis and biological evaluation of piperidine-4-carboxamide derivatives. Bioorganic & medicinal chemistry 20050117
Optimization of pyrrolidinone based HIV protease inhibitors. Bioorganic & medicinal chemistry letters 20050103
Rapid, single-tube method for quantitative preparation and analysis of RNA and DNA in samples as small as one cell. BMC biotechnology 20050101
Interaction of silver nanoparticles with HIV-1. Journal of nanobiotechnology 20050101
Effect of penetration enhancers on the transdermal delivery of bupranolol through rat skin. Drug delivery 20050101
Generation and analysis of 9792 EST sequences from cold acclimated oat, Avena sativa. BMC plant biology 20050101
Sequence homology: a poor predictive value for profilins cross-reactivity. Clinical and molecular allergy : CMA 20050101
A fully automatable enzymatic method for DNA extraction from plant tissues. BMC plant biology 20050101
Efficient gene-driven germ-line point mutagenesis of C57BL/6J mice. BMC genomics 20050101
Preparation of water-soluble magnetite nanocrystals from hydrated ferric salts in 2-pyrrolidone: mechanism leading to Fe3O4. Angewandte Chemie (International ed. in English) 20041217
Discovery of potent pyrrolidone-based HIV-1 protease inhibitors with enhanced drug-like properties. Bioorganic & medicinal chemistry letters 20041115
Regioselectivity in iron-catalyzed [2+2+1] cycloadditions: a DFT investigation of substituent effects in 1,4-diazabutadienes. Chemistry (Weinheim an der Bergstrasse, Germany) 20041105
Rapid induction of splenic and peritoneal B-1a cells in adult mice by thymus-independent type-2 antigen. Journal of immunology (Baltimore, Md. : 1950) 20041101
Extracting DNA from submerged pine wood. Genome 20041001
The effect of penetration enhancers on drug delivery through skin: a QSAR study. Journal of controlled release : official journal of the Controlled Release Society 20040914
Oxidation of 3-hydroxypiperidines with iodosylbenzene in water: tandem oxidative Grob fragmentation-cyclization reaction. Chemical & pharmaceutical bulletin 20040901
Development and evaluation of biocompatible inks for the local measurement of oxygen using in vivo EPR. NMR in biomedicine 20040801
Structural variations in keto-glutamines for improved inhibition against hepatitis A virus 3C proteinase. Bioorganic & medicinal chemistry letters 20040716
Design of temperature sensitive imprinted polymer hydrogels based on multiple-point hydrogen bonding. Macromolecular bioscience 20040714
Rapid dissolution of high-potency danazol particles produced by evaporative precipitation into aqueous solution. Journal of pharmaceutical sciences 20040701
Molecular dynamics study of the interactions of ice inhibitors on the ice {001} surface. Langmuir : the ACS journal of surfaces and colloids 20040622
Mechanism of growth of colloidal silver nanoparticles stabilized by polyvinyl pyrrolidone in gamma-irradiated silver nitrate solution. Journal of colloid and interface science 20040601
Total synthesis of (-)-dysibetaine via a nitrenium ion cyclization-dienone cleavage strategy. Chemical communications (Cambridge, England) 20040521
The effect of dehydration history on PVA/PVP hydrogels for nucleus pulposus replacement. Journal of biomedical materials research. Part B, Applied biomaterials 20040515
Micelles from lipid derivatives of water-soluble polymers as delivery systems for poorly soluble drugs. Advanced drug delivery reviews 20040507
Lactams as EP4 prostanoid receptor subtype selective agonists. Part 1: 2-Pyrrolidinones-stereochemical and lower side-chain optimization. Bioorganic & medicinal chemistry letters 20040405
Penetration enhancers. Advanced drug delivery reviews 20040327
Comparative pharmacokinetics and metabolism of levetiracetam, a new anti-epileptic agent, in mouse, rat, rabbit and dog. Xenobiotica; the fate of foreign compounds in biological systems 20040301
Properties and biocompatibility of polypropylene graft copolymer films. Journal of biomedical materials research. Part B, Applied biomaterials 20040215
Process and formulation variables affecting the performance of a rupturable capsule-based drug delivery system with pulsatile drug release. Drug development and industrial pharmacy 20040201
Discovery of 4-substituted pyrrolidone butanamides as new agents with significant antiepileptic activity. Journal of medicinal chemistry 20040129
Polyvinylpyrrolidone-drug conjugate: synthesis and release mechanism. Journal of controlled release : official journal of the Controlled Release Society 20040108
Vitrification of bovine oocytes and its application to intergeneric somatic cell nucleus transfer. Theriogenology 20040101
CCR5 antagonists as anti-HIV-1 agents. 1. Synthesis and biological evaluation of 5-oxopyrrolidine-3-carboxamide derivatives. Chemical & pharmaceutical bulletin 20040101
[Regulating effect of gamma-aminobutyric acid and pyrrolidone-2 on endogenous blood metalloproteins with anti- and pro-oxidant activity in hypoxia]. Eksperimental'naia i klinicheskaia farmakologiia 20040101
Polyvinyl pyrrolidone: a novel cryoprotectant in islet cell cryopreservation. Cell transplantation 20040101
[Functional-behavioral profile of new cyclic GABA analogs in acute toxicity tests]. Eksperimental'naia i klinicheskaia farmakologiia 20040101
Development of matrix-membrane transdermal drug delivery system for atenolol. Drug delivery 20040101
Non-peptide alpha(v)beta(3) antagonists: identification of potent, chain-shortened RGD mimetics that incorporate a central pyrrolidinone constraint. Bioorganic & medicinal chemistry letters 20031215
Dioxygen-coupled oxidative amination of styrene. Journal of the American Chemical Society 20031029
Mucoadhesive buccal patches of miconazole nitrate: in vitro/in vivo performance and effect of ageing. International journal of pharmaceutics 20031002
Developmental outcome of levetiracetam, its major metabolite in humans, 2-pyrrolidinone N-butyric acid, and its enantiomer (R)-alpha-ethyl-oxo-pyrrolidine acetamide in a mouse model of teratogenicity. Epilepsia 20031001
Formation of vinylogous compounds in model Maillard reaction systems. Chemical research in toxicology 20031001
Enhanced bleomycin-induced pulmonary damage in mice lacking extracellular superoxide dismutase. Free radical biology & medicine 20031001
Evaluation of critical formulation factors in the development of a rapidly dispersing captopril oral dosage form. Drug development and industrial pharmacy 20031001
2-pyrrolidinone induces a long-lasting facilitation of hippocampal synaptic transmission by enhancing alpha7 ACh receptor responses via a PKC pathway. Brain research. Molecular brain research 20030910
1-[2-(4-nitrophenoxy)acetyl]pyrrolidin-2-one: an antiamnesic agent. Acta crystallographica. Section C, Crystal structure communications 20030901
2-pyrrolidinone moiety is not critical for the cognition-enhancing activity of piracetam-like drugs. Farmaco (Societa chimica italiana : 1989) 20030901
Vibrational and electronic couplings in ultraviolet resonance Raman spectra of cyclic peptides. Biophysical chemistry 20030901
Chemical and olfactory characterization of odorous compounds and their precursors in the parotoid gland secretion of the green tree frog, Litoria caerulea. Journal of chemical ecology 20030901
Design and characterization of mucoadhesive buccal patches containing cetylpyridinium chloride. Acta pharmaceutica (Zagreb, Croatia) 20030901
Pyrrolidinobenzoic acid inhibitors of influenza virus neuraminidase: modifications of essential pyrrolidinone ring substituents. Bioorganic & medicinal chemistry 20030703
Dichloroketene-chiral olefin-based approach to pyrrolizidines: highly stereocontrolled synthesis of (+)-amphorogynine A. Organic letters 20030515
Effective inhibition of mannitol crystallization in frozen solutions by sodium chloride. Pharmaceutical research 20030401
A theoretical study on the complete catalytic cycle of the hetero-Pauson-Khand-type [2+2+1] cycloaddition reaction of ketimines, carbon monoxide and ethylene catalyzed by iron carbonyl complexes. Chemistry (Weinheim an der Bergstrasse, Germany) 20030303
Pyroglutamyl-peptidase I: cloning, sequencing, and characterisation of the recombinant human enzyme. Protein expression and purification 20030301
A study of 5-aminolevulinic acid and its methyl ester used in in vitro and in vivo systems of human bladder cancer. International journal of oncology 20030201
[Neuroprotective properties of pyroglutamic acid in combination with pyrrolidone]. Eksperimental'naia i klinicheskaia farmakologiia 20030101
Source reduction for prevention of methylene chloride hazards: cases from four industrial sectors. Environmental health : a global access science source 20030101
A general treatment of solubility. 1. The QSPR correlation of solvation free energies of single solutes in series of solvents. Journal of chemical information and computer sciences 20030101
Pyrrolidonyl and pyridyl alkaloids in Lymantria dispar. Zeitschrift fur Naturforschung. C, Journal of biosciences 20030101
[Characteristics of pyrrolidone pharmacokinetics in rats]. Eksperimental'naia i klinicheskaia farmakologiia 20030101
Development and in-vitro evaluation of sustained release poloxamer 407 (P407) gel formulations of ceftiofur. Journal of controlled release : official journal of the Controlled Release Society 20021213
Novel spirocyclic pyrrolidones as P2/P1 mimetics in potent inhibitors of HIV-1 protease. Bioorganic & medicinal chemistry letters 20021202
Design of inhibitors of scytalone dehydratase: probing interactions with an asparagine carboxamide. Bioorganic & medicinal chemistry 20021201
GABA and glutamate in the human brain. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 20021201
Nefiracetam induces a long-lasting facilitation of hippocampal postsynaptic responses in mice lacking the NMDA receptor epsilon1 subunit. Brain research 20021122
Enantioselective Michael additions of nitromethane by a catalytic double activation method using chiral lewis Acid and achiral amine catalysts. Journal of the American Chemical Society 20021113
N-Arylated pyrrolidin-2-ones and morpholin-3-ones as potassium channel openers. Bioorganic & medicinal chemistry 20021001
Influence of storage time and temperature on the stability of indomethacin Pluronic F-127 gels. Die Pharmazie 20021001
Radical carboazidation of alkenes: an efficient tool for the preparation of pyrrolidinone derivatives. Angewandte Chemie (International ed. in English) 20020916
Evaluation of solid dispersions of Clofazimine. Drug development and industrial pharmacy 20020901
Geographic variation of natural products of tropical nudibranch Asteronotus cespitosus. Journal of chemical ecology 20020901
Palladium-catalyzed aminoallylation of activated olefins with allylic halides and phthalimide. The Journal of organic chemistry 20020823
A new tin-free source of amidyl radicals. Organic letters 20020808
Dermal exposure to aqueous solutions of N-methyl pyrrolidone. Toxicology letters 20020805
Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure. Effects of the quaternization of the basic nitrogen on the interaction with 5-HT(3) receptor. Bioorganic & medicinal chemistry 20020801
Transdermal delivery of physostigmine: effects of enhancers and pressure-sensitive adhesives. Drug development and industrial pharmacy 20020801
Acylating agents as enzyme inhibitors and understanding their reactivity for drug design. Journal of medicinal chemistry 20020620
Induction of endothelial cell apoptosis by the antivascular agent 5,6-Dimethylxanthenone-4-acetic acid. British journal of cancer 20020617
Effect of water on the molecular mobility of sucrose and poly(vinylpyrrolidone) in a colyophilized formulation as measured by (13)C-NMR relaxation time. Chemical & pharmaceutical bulletin 20020601
Acetylenic polymers for hair styling products. International journal of cosmetic science 20020601
Interaction of influenza A virus M1 matrix protein with caspases. Biochemistry. Biokhimiia 20020501
Effect of the absence or presence of various protein supplements on further development of bovine oocytes during in vitro maturation. Biology of reproduction 20020401
Novel potent 5-HT(3) receptor ligands based on the pyrrolidone structure: synthesis, biological evaluation, and computational rationalization of the ligand-receptor interaction modalities. Bioorganic & medicinal chemistry 20020301
BAL 9141, a new broad-spectrum pyrrolidinone cephalosporin: activity against clinically significant anaerobes in comparison with 10 other antimicrobials. The Journal of antimicrobial chemotherapy 20020301
Evaluation of CC2 as a decontaminant in various hydrophilic and lipophilic formulations against sulphur mustard. Biomedical and environmental sciences : BES 20020301
Penicillin-resistant Aerococcus viridans bacteremia associated with granulocytopenia. Journal of Korean medical science 20020201
The aniracetam metabolite 2-pyrrolidinone induces a long-term enhancement in AMPA receptor responses via a CaMKII pathway. Brain research. Molecular brain research 20020131
Catalytic asymmetric intramolecular aminopalladation: enantioselective synthesis of vinyl-substituted 2-oxazolidinones, 2-imidazolidinones, and 2-pyrrolidinones. Journal of the American Chemical Society 20020109
Regional differences in expression of VEGF mRNA in rat gastrocnemius following 1 hr exercise or electrical stimulation. BMC physiology 20020101
[Effect of a drug composition containing pyroglutamic acid and pyrrolidone on the cerebral circulation]. Eksperimental'naia i klinicheskaia farmakologiia 20020101
Electrophilic fluorination of pyroglutamic acid derivatives: application of substrate-dependent reactivity and diastereoselectivity to the synthesis of optically active 4-fluoroglutamic acids. The Journal of organic chemistry 20011228
Synthesis and characterization of tetramethylrhodaminethiocarbamoyl-(Glu(1))-epidermal mitosis-inhibiting pentapeptide. Regulatory peptides 20011215
Pyrrolidone derivatives. Lancet (London, England) 20011201
Amphiphilic poly-N-vinylpyrrolidones: synthesis, properties and liposome surface modification. Biomaterials 20011101
The effect of polyvinyl pyrrolidone on the clinical activity of 0.09% and 0.2% chlorhexidine mouthrinses. Journal of clinical periodontology 20011101
Antidepressant-like effects of aniracetam in aged rats and its mode of action. Psychopharmacology 20011101
Degradation of imidacloprid in water by photo-Fenton and TiO2 photocatalysis at a solar pilot plant: a comparative study. Environmental science & technology 20011101
Characterization of the solubility and dissolution properties of several new rifampicin polymorphs, solvates, and hydrates. Drug development and industrial pharmacy 20011101
Aniracetam enhances cortical dopamine and serotonin release via cholinergic and glutamatergic mechanisms in SHRSP. Brain research 20011019
Synthesis of valproic acid amides of a melatonin derivative, a piracetam and amantadine for biological tests. Neurochemical research 20011001
Extraction of human DNA for PCR from chewed residues of betel quid using a novel 'PVP/CTAB' method. Journal of forensic sciences 20010901
Influences of alkyl group chain length and polar head group on chemical skin permeation enhancement. Journal of pharmaceutical sciences 20010801
Influence of fluorophor dye labels on the migration behavior of polymerase chain reaction--amplified short tandem repeats during denaturing capillary electrophoresis. Electrophoresis 20010801
A comparison of alternative polymer excipients and processing methods for making solid dispersions of a poorly water soluble drug. International journal of pharmaceutics 20010703
Fourier transform Raman spectroscopic study of the interaction of water vapor with amorphous polymers. Journal of pharmaceutical sciences 20010701
Pharmacokinetics of levetiracetam and its enantiomer (R)-alpha-ethyl-2-oxo-pyrrolidine acetamide in dogs. Epilepsia 20010701
Synthesis of ent-alantrypinone. Journal of the American Chemical Society 20010627
Studies on the effect of polyvinyl pyrrolidone on the activity of chlorhexidine mouthrinses: plaque and stain. Journal of clinical periodontology 20010601
Control and stability of drug release from diffusion pellets coated with the aqueous quaternary polymethacrylate dispersion Eudragit RS 30 D. Die Pharmazie 20010601
The design of competitive, small-molecule inhibitors of coagulation factor Xa. Current topics in medicinal chemistry 20010601
The mechanism of aubstrate eecognition of pyroglutamyl-peptidase I from Bacillus amyloliquefaciens as determined by X-ray crystallography and site-directed mutagenesis. The Journal of biological chemistry 20010525
Design and synthesis of 2-oxo-imidazolidine-4-carboxylic acid hydroxyamides as potent matrix metalloproteinase-13 inhibitors. Bioorganic & medicinal chemistry letters 20010507
Full term development of rabbit oocytes fertilized by intracytoplasmic sperm injection. Molecular reproduction and development 20010501
Efficacy of topical phenol decontamination strategies on severity of acute phenol chemical burns and dermal absorption: in vitro and in vivo studies in pig skin. Toxicology and industrial health 20010501
Removal of N-terminal blocking groups from proteins. Current protocols in protein science 20010501
In vivo assessment of enhanced topical delivery of terbinafine to human stratum corneum. Journal of controlled release : official journal of the Controlled Release Society 20010428
Rational design, synthesis, and biological evaluation of rigid pyrrolidone analogues as potential inhibitors of prostate cancer cell growth. Bioorganic & medicinal chemistry letters 20010423
Single molecule DNA sequencing in submicrometer channels: state of the art and future prospects. Journal of biotechnology 20010413
Site-specific activation of dopamine and serotonin transmission by aniracetam in the mesocorticolimbic pathway of rats. Brain research 20010406
A pyrrolidinone derivative inhibits cytokine-induced iNOS expression and NF-kappaB activation by preventing phosphorylation and degradation of IkappaB-alpha. Journal of biochemistry 20010401
Solvent effects on dimeric self-association of 2-pyrrolidinone: an ab initio study. Journal of computer-aided molecular design 20010401
Topiramate rapidly raises brain GABA in epilepsy patients. Epilepsia 20010401
Homocarnosine and seizure control in juvenile myoclonic epilepsy and complex partial seizures. Neurology 20010327
Synthesis of pyrrolidinone PNA: a novel conformationally restricted PNA analogue. The Journal of organic chemistry 20010209
Separation of multicomponent mixtures of 2,4-dinitrophenyl labelled amino acids and their enantiomers by capillary zone electrophoresis. Electrophoresis 20010201
Crystallization of hydrocortisone acetate: influence of polymers. International journal of pharmaceutics 20010116
Selected reaction monitoring LC-MS determination of idoxifene and its pyrrolidinone metabolite in human plasma using robotic high-throughput, sequential sample injection. Analytical chemistry 20010101
Fusogenic activity of vesicular stomatitis virus glycoprotein plasmid in tumors as an enhancer of IL-12 gene therapy. Cancer gene therapy 20010101
Characterization of protein-loaded poly(epsilon-caprolactone) microparticles based on a factorial design. Journal of microencapsulation 20010101
Optimization of DNA electrophoretic behavior in poly(vinyl pyrrolidone) sieving matrix for DNA sequencing. Electrophoresis 20010101
Rapid single nucleotide polymorphism analysis by primer extension and capillary electrophoresis using polyvinyl pyrrolidone matrix. Electrophoresis 20010101
Nefiracetam improves Morris water maze performance following traumatic brain injury in rats. Pharmacology, biochemistry, and behavior 20010101
Identification of odoriferous compounds from adults of a swallowtail butterfly, Papilio machaon (Lepidoptera: Papilionidae). Zeitschrift fur Naturforschung. C, Journal of biosciences 20010101
Properties of polyvinyl pyrrolidone/beta-chitosan hydrogel membranes and their biocompatibility evaluation by haemorheological method. Journal of materials science. Materials in medicine 20010101
Properties