2-Methyl-2-thiopseudourea hemisulfate hemihydrate
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The comparative proteomics analysis revealed the modulation of inducible nitric oxide on the immune response of scallop Chlamys farreri. | Fish & shellfish immunology 20141001 |
The regulatory role of the NO/cGMP signal transduction cascade during larval attachment and metamorphosis of the barnacle Balanus (=Amphibalanus) amphitrite. | The Journal of experimental biology 20121101 |
Effect of S-methylisothiourea in acetaminophen-induced hepatotoxicity in rat. | Naunyn-Schmiedeberg's archives of pharmacology 20121101 |
Protective effects of melatonin and S-methylisothiourea on mechlorethamine induced nephrotoxicity. | The Journal of surgical research 20120601 |
The role of iNOS inhibitors on lung injury induced by gastrointestinal decontamination agents aspiration. | Journal of molecular histology 20120601 |
Cytochrome-c mediated a bystander response dependent on inducible nitric oxide synthase in irradiated hepatoma cells. | British journal of cancer 20120227 |
Effects of nitric oxide on the survival and neuritogenesis of cerebellar Purkinje neurons. | Journal of molecular neuroscience : MN 20120201 |
15-Hydroxyeicosatetraenoic acid (15-HETE) protects pulmonary artery smooth muscle cells from apoptosis via inducible nitric oxide synthase (iNOS) pathway. | Prostaglandins & other lipid mediators 20120101 |
S-methylisothiourea induces apoptosis of herpes simplex virus-1-infected microglial cells. | Inflammation 20111001 |
Manganese porphyrin reduces retinal injury induced by ocular hypertension in rats. | Experimental eye research 20111001 |
Impairment of acetylcholine-mediated endothelium-dependent relaxation in isolated parotid artery of the alloxan-induced diabetic rabbit. | European journal of oral sciences 20111001 |
Regional difference in inflammatory response to LPS-injection in the brain: role of microglia cell density. | Journal of neuroimmunology 20110915 |
Inhibition of iNOS reduces the therapeutic effects of ozone in acute necrotizing pancreatitis: an in vivo animal study. | Scandinavian journal of clinical and laboratory investigation 20110901 |
Role of nitric oxide in the regulation of fibrogenic factors in experimental liver fibrosis in mice. | Histology and histopathology 20110201 |
Protein kinase A-dependent neuronal nitric oxide synthase activation mediates the enhancement of baroreflex response by adrenomedullin in the nucleus tractus solitarii of rats. | Journal of biomedical science 20110101 |
Synthetic studies on novel 1,4-dihydro-2-methylthio-4,4,6-trisubstituted pyrimidine-5-carboxylic acid esters and their tautomers. | Chemical & pharmaceutical bulletin 20110101 |
Hemodynamic effects of inducible nitric oxide synthase inhibition combined with sildenafil during acute pulmonary embolism. | Nitric oxide : biology and chemistry 20101215 |
Effect of selective inhibitors of nitric oxide synthesis on the course of experimental hemorrhagic shock. | Bulletin of experimental biology and medicine 20101001 |
Inhibition of nitric oxide synthesis during induced cholestasis ameliorates hepatocellular injury by facilitating S-nitrosothiol homeostasis. | Laboratory investigation; a journal of technical methods and pathology 20100101 |
Neuroprotective effect of s-methylisothiourea in transient focal cerebral ischemia in rat. | Nitric oxide : biology and chemistry 20100101 |
Evaluation of effects of s-methyl isothiourea and melatonin on intestinal ischemia/reperfusion injury in rats. | Fetal and pediatric pathology 20100101 |
Sympathoinhibitory mechanism of moxonidine: role of the inducible nitric oxide synthase in the rostral ventrolateral medulla. | Cardiovascular research 20091101 |
Nitric oxide and superoxide anion differentially activate poly(ADP-ribose) polymerase-1 and Bax to induce nuclear translocation of apoptosis-inducing factor and mitochondrial release of cytochrome c after spinal cord injury. | Journal of neurotrauma 20090701 |
Effect of microglia activation on dopaminergic neuronal injury induced by manganese, and its possible mechanism. | Neurotoxicity research 20090701 |
[Nitrogen monoxide and functional activity of large conductance Ca-activated potassium channels in coronary vessels in rats with limited motor activity]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20090701 |
Influence of propofol on blood pressure spectrum in sepsis and the role of inducible nitric oxide synthase. | Acta anaesthesiologica Taiwanica : official journal of the Taiwan Society of Anesthesiologists 20090601 |
Endothelial nitric oxide synthase is a critical factor in experimental liver fibrosis. | International journal of experimental pathology 20080801 |
Protective effects of S-methylisothiourea sulfate on different aspiration materials-induced lung injury in rats. | International journal of pediatric otorhinolaryngology 20080801 |
Melatonin inhibits amphetamine-induced nitric oxide synthase mRNA overexpression in microglial cell lines. | Neuroscience letters 20080711 |
Intermittent hypoxia modulates nitric oxide-dependent vasodilation and capillary perfusion during ischemia-reperfusion-induced damage. | American journal of physiology. Heart and circulatory physiology 20080401 |
The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: an isobolographic study. | Anesthesia and analgesia 20080301 |
Mechanisms of microglia-mediated neurotoxicity in a new model of the stroke penumbra. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20080227 |
Scavenging of peroxynitrite reduces renal ischemia/reperfusion injury. | Renal failure 20080101 |
Malignant alterations following early blockade of nitric oxide synthase in hypertensive rats. | The Chinese journal of physiology 20071231 |
Different roles of nitric oxide synthase-1 and -2 between herpetic and postherpetic allodynia in mice. | Neuroscience 20071205 |
A triterpenediol from Boswellia serrata induces apoptosis through both the intrinsic and extrinsic apoptotic pathways in human leukemia HL-60 cells. | Apoptosis : an international journal on programmed cell death 20071001 |
Antagonism of lipopolysaccharide-induced blood pressure attenuation and vascular contractility. | Arteriosclerosis, thrombosis, and vascular biology 20071001 |
Neuritin (cpg15) enhances the differentiating effect of NGF on neuronal PC12 cells. | Journal of neuroscience research 20070901 |
Probing the structure and activity of trypsin with amidination. | Analytical biochemistry 20070801 |
Enhanced beta-adrenergic response in rat papillary muscle by inhibition of inducible nitric oxide synthase after myocardial infarction. | Acta physiologica (Oxford, England) 20070601 |
[Animal experimental study of intra-articular injection of S-methylisothiourea for treatment of temporomandibular joint osteoarthrosis]. | Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20070601 |
Responsiveness to inhaled NO in isolated-perfused lungs from endotoxin-challenged rats is dependent on endogenous nitrite/nitrate synthesis. | European journal of anaesthesiology 20070401 |
Inhibition of inducible nitric oxide synthase attenuates acute endotoxin-induced lung injury in rats. | Clinical and experimental pharmacology & physiology 20070401 |
Interaction between inhibitors of inducible nitric oxide synthase and cyclooxygenase in adjuvant-induced arthritis in female albino rats: an isobolographic study. | European journal of pharmacology 20070205 |
[Influence of induced nitric oxide synthase expression on apoptosis of thymocyte in burn rats]. | Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20061201 |
NO-synthase inhibitors provide influence on protective effect of modified endotoxine diphosphoryl lipid A in a rat heart model of ischemic-reperfusion injury. | Die Pharmazie 20060601 |
Cannabidiol inhibits inducible nitric oxide synthase protein expression and nitric oxide production in beta-amyloid stimulated PC12 neurons through p38 MAP kinase and NF-kappaB involvement. | Neuroscience letters 20060515 |
Phenotypic adaptation of the late preconditioned heart: myocardial oxygen consumption is reduced. | Cardiovascular research 20060501 |
The astroglial-derived S100beta protein stimulates the expression of nitric oxide synthase in rodent macrophages through p38 MAP kinase activation. | Life sciences 20060501 |
COX-2 mediates morphine-induced delayed cardioprotection via an iNOS-dependent mechanism. | Life sciences 20060425 |
Microglia induce neural cell death via a proximity-dependent mechanism involving nitric oxide. | Brain research 20060421 |
Toll-like receptor 4, nitric oxide, and myocardial depression in endotoxemia. | Shock (Augusta, Ga.) 20060101 |
Mechanism of hepatic heme oxygenase-1 induction by isoflurane. | Anesthesiology 20060101 |
Reinforcement therapy using nitric oxide synthase inhibitors against endotoxin shock in dogs. | Surgery today 20060101 |
Nitric oxide- and superoxide-dependent mitochondrial signaling in endotoxin-induced apoptosis in the rostral ventrolateral medulla of rats. | Free radical biology & medicine 20050901 |
High levels of endogenous nitric oxide produced after burn injury in rats arrest activated T lymphocytes in the first G1 phase of the cell cycle and then induce their apoptosis. | Experimental cell research 20050515 |
Inducible nitric oxide synthase inhibition potentiates multiple organ dysfunction induced by endotoxin in conscious rats. | Journal of cardiovascular pharmacology 20050501 |
Inhibition of iNOS with S-methylisothiourea was impaired in wound healing in caustic esophageal burn. | International journal of pediatric otorhinolaryngology 20050401 |
Interaction between inhibitors of inducible nitric oxide synthase and cyclooxygenase in Brewer's yeast induced pyrexia in mice: an isobolographic study. | European journal of pharmacology 20050328 |
[Inhibition of nitric oxide synthesis during bacterial shock does not prevent development of resistant hypotension and death in rats]. | Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994) 20050101 |
[Platelet aggregation in modulation of the pathway L-arginine-NO in rats with cerebral ischemia]. | Patologicheskaia fiziologiia i eksperimental'naia terapiia 20050101 |
Involvement of inducible nitric oxide synthase in renal failure after mild hemorrhage. | Legal medicine (Tokyo, Japan) 20041001 |
Pharmacological manipulation of nitric oxide levels in mouse follicle cultures demonstrates key role of extrafollicular control of ovulation. | Human reproduction (Oxford, England) 20040801 |
Inducible nitric oxide synthase mediates delayed cardioprotection induced by morphine in vivo: evidence from pharmacologic inhibition and gene-knockout mice. | Anesthesiology 20040701 |
Inhibition of NOS2 ameliorates cardiac remodeling, improves heart function after myocardial infarction in rats. | Basic research in cardiology 20040701 |
Modulation of iNOS activity in age-related cardiac dysfunction. | Life sciences 20040625 |
Decrease in arterial pressure induced by adrenomedullin in the hypothalamic paraventricular nucleus is mediated by nitric oxide and GABA. | Regulatory peptides 20040615 |
Inducible nitric oxide synthase inhibition in cyclophosphamide induced hemorrhagic cystitis in rats. | Urological research 20040601 |
COX-2 and iNOS in opioid-induced delayed cardioprotection in the intact rat. | Life sciences 20040528 |
Down-regulation of cytochrome P450 proteins and its activities by Shiga-like toxin II from Escherichia coli O157:H7. | Biochemical pharmacology 20040415 |
Sublethal simulated ischemia promotes delayed resistance against ischemia via ATP-sensitive (K+) channels in murine myocytes: role of PKC and iNOS. | Antioxidants & redox signaling 20040401 |
Improvement of intestinal motility using S-methylisothiourea in postoperative ileus. | American journal of surgery 20040101 |
Involvement of nitric oxide and hyperbaric oxygen in the pathogenesis of cyclophosphamide induced hemorrhagic cystitis in rats. | The Journal of urology 20031201 |
Effect of nitric oxide synthase inhibitor on proteoglycan metabolism in repaired articular cartilage in rabbits. | Chinese journal of traumatology = Zhonghua chuang shang za zhi 20031201 |
Modulation of nerve growth factor-induced activation of MAP kinase in PC12 cells by inhibitors of nitric oxide synthase. | Journal of neurochemistry 20031201 |
Reversal of the effect of albumin on gut barrier function in burn by the inhibition of inducible isoform of nitric oxide synthase. | Archives of surgery (Chicago, Ill. : 1960) 20031101 |
Lipopolysaccharide down-regulates inducible nitric oxide synthase expression in swine heart in vivo. | Biochemical and biophysical research communications 20030801 |
Downregulation of angiotensin subtype 1 receptor in rostral ventrolateral medulla during endotoxemia. | Hypertension (Dallas, Tex. : 1979) 20030701 |
The role of inducible nitric oxide synthase inhibitor, meropenem, and taurine in experimental acute necrotizing pancreatitis. | Pancreas 20030501 |
Effect of venom from the scorpion Leiurus quinquestriatus on rat vascular aortic rings. | Journal of basic and clinical physiology and pharmacology 20030101 |
Increased nitric oxide production by neutrophils from patients with chronic granulomatous disease on trimethoprim-sulfamethoxazole. | Nitric oxide : biology and chemistry 20021201 |
Aminoguanidine inhibits mitogen-activated protein kinase and improves cardiac performance and cardiovascular remodeling in failing hearts of salt-sensitive hypertensive rats. | Journal of hypertension 20021201 |
Nitric oxide modulates myocardial oxygen consumption in the failing heart. | Circulation 20020709 |
Inhibition of NOS II prevents cardiac dysfunction in myocardial infarction and congestive heart failure. | American journal of physiology. Heart and circulatory physiology 20020701 |
Differential activity of NO synthase inhibitors as chemopreventive agents in a primary rat tracheal epithelial cell transformation system. | Neoplasia (New York, N.Y.) 20020701 |
Inhibitors of nitric oxide synthase attenuate nerve growth factor-mediated increases in choline acetyltransferase expression in PC12 cells. | Journal of neurochemistry 20020501 |
Kupffer cells protect liver from ischemia-reperfusion injury by an inducible nitric oxide synthase-dependent mechanism. | Shock (Augusta, Ga.) 20020401 |
Differential effects of selective and non-selective NOS inhibition on renal arginine and protein metabolism during endotoxemia in rats. | Clinical nutrition (Edinburgh, Scotland) 20020401 |
Effects of ornithine 2-oxoglutarate on neutrophils in stressed rats: evidence for the involvement of nitric oxide and polyamines. | Clinical science (London, England : 1979) 20020301 |
[Long-term effect of nitric oxide synthase inhibitor on repair of articular cartilage defects repairing]. | Zhonghua yi xue za zhi 20020110 |
Renal effects of nitric oxide in endotoxemia. | American journal of respiratory and critical care medicine 20011115 |
High levels of nitric oxide production decrease early but increase late survival of Brucella abortus in macrophages. | Microbial pathogenesis 20011101 |
Reduced functional expression and molecular synthesis of inducible nitric oxide synthase in rostral ventrolateral medulla of spontaneously hypertensive rats. | Circulation 20011002 |
Involvement of nitric oxide released from microglia-macrophages in pathological changes of cathepsin D-deficient mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20011001 |
Inhibition of inducible nitric oxide synthase reduces bacterial translocation in a rat model of acute pancreatitis. | Pancreas 20011001 |
Intestinal motility in an in vivo rat model of intestinal ischemia-reperfusion with special reference to the effects of nitric oxide on the motility changes. | Journal of pediatric gastroenterology and nutrition 20010901 |
A novel method of studying wound healing. | The Journal of surgical research 20010601 |
Lipopolysaccharide-induced cell cycle arrest in macrophages occurs independently of nitric oxide synthase II induction. | Biochimica et biophysica acta 20010528 |
Expression of inducible nitric oxide synthase in primary culture of rat bladder smooth muscle cells by plasma from cyclophosphamide-treated rats. | European journal of pharmacology 20010323 |
Intestinal ischemia induces late preconditioning against myocardial infarction: a role for inducible nitric oxide synthase. | Cardiovascular research 20010201 |
Inhibition of inducible nitric oxide synthase (iNOS) prevents lung neutrophil deposition and damage in burned rats. | Shock (Augusta, Ga.) 20010201 |
Role of nitric oxide in human gastric cancer cells treated with 5-fluorouracil. | Oncology reports 20010101 |
Inducible nitric oxide synthase mediates delayed myocardial protection induced by activation of adenosine A(1) receptors: evidence from gene-knockout mice. | Circulation 20000822 |
Reduction of myocardial infarct size by inhibition of inducible nitric oxide synthase. | American journal of hypertension 19990201 |
Expression and function of inducible nitric oxide synthase during rat colon anastomotic healing. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 19990101 |
Selective iNOS inhibition is superior to norepinephrine in the treatment of rat endotoxic shock. | American journal of respiratory and critical care medicine 19980101 |
Timing of administration of dexamethasone or the nitric oxide synthase inhibitor, nitro-L-arginine methyl ester, is critical for effective treatment of ischaemia-reperfusion injury to rat skeletal muscle. | Clinical science (London, England : 1979) 19970801 |