2-Azetidinone
| Title | Journal |
|---|---|
| Ring splitting of azetidin-2-ones via radical anions. | Organic & biomolecular chemistry 20121021 |
| An expeditious iodine-catalyzed synthesis of 3-pyrrole-substituted 2-azetidinones. | Molecules (Basel, Switzerland) 20120928 |
| The vascular targeting agent Combretastatin-A4 directly induces autophagy in adenocarcinoma-derived colon cancer cells. | Biochemical pharmacology 20120901 |
| Photoelectron spectra of some antibiotic building blocks: 2-azetidinone and thiazolidine-carboxylic acid. | The journal of physical chemistry. A 20120823 |
| An expeditious route to eight-membered heterocycles by nickel-catalyzed cycloaddition: low-temperature C(sp)2-C(sp)3 bond cleavage. | Angewandte Chemie (International ed. in English) 20120820 |
| Kappa agonist CovX-Bodies. | Bioorganic & medicinal chemistry letters 20120615 |
| Regioselective cycloaddition of 3-azetidinones and 3-oxetanones with alkynes through nickel-catalysed carbon-carbon bond activation. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120319 |
| Novel pyrazole derivatives as anticancer and radiosensitizing agents. | Arzneimittel-Forschung 20120301 |
| Binding of β-lactam antibiotics to a bioinspired dizinc complex reminiscent of the active site of metallo-β-lactamases. | Inorganic chemistry 20120220 |
| Synthesis, in vitro antitubercular activity and 3D-QSAR of novel quinoxaline derivatives. | Chemical biology & drug design 20111201 |
| Synthesis and bioactivities of 2-azetidinone derivatives as cholesterol absorption inhibitors. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20111101 |
| Antibacterial agents and cystic fibrosis: synthesis and antimicrobial evaluation of a series of N-thiomethylazetidinones. | ChemMedChem 20111004 |
| (E)-4-Phenyl-butan-2-one oxime. | Acta crystallographica. Section E, Structure reports online 20110901 |
| A formal synthesis of ezetimibe via cycloaddition/rearrangement cascade reaction. | The Journal of organic chemistry 20110819 |
| Antiplasmodial and cytotoxicity evaluation of 3-functionalized 2-azetidinone derivatives. | Bioorganic & medicinal chemistry letters 20110801 |
| Poly[(μ(3)-rac-5-eth-oxy-carbonyl-6-hy-droxy-6-methyl-4-phenyl-4,5,6,7-tetra-hydro-benzo[c]isoxazol-3-olato)potassium]. | Acta crystallographica. Section E, Structure reports online 20110601 |
| Development of biomimetic catalytic oxidation methods and non-salt methods using transition metal-based acid and base ambiphilic catalysts. | Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511 |
| Synthesis of spirocyclic β-keto-lactams: copper catalyzed process. | Chemical communications (Cambridge, England) 20110507 |
| Synthesis, evaluation and structural studies of antiproliferative tubulin-targeting azetidin-2-ones. | Bioorganic & medicinal chemistry 20110401 |
| 1-(4-Meth-oxy-phen-yl)-4-(3-nitro-phen-yl)-3-phen-oxy-azetidin-2-one. | Acta crystallographica. Section E, Structure reports online 20110201 |
| Conventional and microwave assisted synthesis of 2-oxo-4-substituted aryl-azetidine derivatives of benzotriazole: a new class of biological compounds. | Bioorganic & medicinal chemistry letters 20110101 |
| Monocyclic β-lactams: new structures for new biological activities. | Current medicinal chemistry 20110101 |
| 3D QSAR pharmacophore modeling, in silico screening, and density functional theory (DFT) approaches for identification of human chymase inhibitors. | International journal of molecular sciences 20110101 |
| Synthesis and Antimicrobial Activities of Some New Azetidin-2-ones and Thiazolidin-4-ones. | Indian journal of pharmaceutical sciences 20110101 |
| Synthesis and evaluation of azetidinone analogues of combretastatin A-4 as tubulin targeting agents. | Journal of medicinal chemistry 20101223 |
| 2-Azetidinone--a new profile of various pharmacological activities. | European journal of medicinal chemistry 20101201 |
| Synthesis of chlorinated bicyclic C-fused tetrahydrofuro[3,2-c]azetidin-2-ones. | The Journal of organic chemistry 20101105 |
| Natural and synthetic inhibitors of kallikrein-related peptidases (KLKs). | Biochimie 20101101 |
| Ferrier-Petasis rearrangement of 4-(vinyloxy)azetidin-2-ones: an entry to carbapenams and carbacephams. | The Journal of organic chemistry 20101015 |
| T-type calcium channel blockers: spiro-piperidine azetidines and azetidinones-optimization, design and synthesis. | Bioorganic & medicinal chemistry letters 20100801 |
| Azetidinone-isothiazolidinones: stereoselective synthesis and antibacterial evaluation of new monocyclic beta-lactams. | Bioorganic & medicinal chemistry 20100501 |
| Synthesis, in-vitro antimicrobial and cytotoxic studies of novel azetidinone derivatives. | Archiv der Pharmazie 20100401 |
| Dietary phospholipids and intestinal cholesterol absorption. | Nutrients 20100201 |
| Suppressed beta-effect of silicon in 3-silylated monocyclic beta-lactams: the role of antiaromaticity. | Organic letters 20091217 |
| Design, synthesis and bioactivity of catechin/epicatechin and 2-azetidinone derived chimeric molecules. | Bioorganic & medicinal chemistry letters 20091215 |
| 2-Azetidinone derivatives: design, synthesis, in vitro anti-microbial, cytotoxic activities and DNA cleavage study. | European journal of medicinal chemistry 20091201 |
| Azetidinones as zinc-binding groups to design selective HDAC8 inhibitors. | ChemMedChem 20091201 |
| Molecular and crystalline structures of three (S)-4-alkoxycarbonyl-2-azetidinones containing long alkyl side chains from synchrotron X-ray powder diffraction data. | Acta crystallographica. Section B, Structural science 20091201 |
| Potential of ezetimibe in memory deficits associated with dementia of Alzheimer's type in mice. | Indian journal of pharmacology 20091201 |
| Lewis acid-assisted ene cyclization of 2-azetidinone-tethered enals: synthesis of enantiopure carbacepham derivatives. | Chemistry, an Asian journal 20091005 |
| (RS/SR)-2-Oxo-4-phenyl-azetidin-3-yl acetate. | Acta crystallographica. Section E, Structure reports online 20091001 |
| A catalytic asymmetric route to carbapenems. | Organic letters 20090820 |
| Studies on the cytotoxic activity of synthetic 2H-azirine-2-azetidinone compounds. | Chemico-biological interactions 20090715 |
| Synthesis and antifungal activity of 2-azetidinonyl-5-(2-benzoylphenoxy)methyl-1,3,4-oxadiazoles against seed-borne pathogens of Eleusine coracana (L.) Gaertn. | Pest management science 20090701 |
| Staudinger ketene-imine cycloaddition, RCM approach to macrocrocyclic bisazetidinones. | The Journal of organic chemistry 20090605 |
| Large ring 1,3-bridged 2-azetidinones: experimental and theoretical studies. | European journal of medicinal chemistry 20090501 |
| 2-Azetidinone derivatives: design, synthesis and evaluation of cholesterol absorption inhibitors. | European journal of medicinal chemistry 20090401 |
| Spiro-piperidine azetidinones as potent TRPV1 antagonists. | Bioorganic & medicinal chemistry letters 20090201 |
| Ring opening at N1-C2 bond of azetidin-2-ones by a molybdenum hydroxo-carbonyl complex: evidence from a computational study. | Dalton transactions (Cambridge, England : 2003) 20081207 |
| Deeper insight into the mechanism of the reaction of photogenerated metallaketenes and imines. | Journal of the American Chemical Society 20081022 |
| Beta-lactam type molecular scaffolds for antiproliferative activity: synthesis and cytotoxic effects in breast cancer cells. | Journal of enzyme inhibition and medicinal chemistry 20081001 |
| Ezetimibe-related myopathy: A systematic review. | Journal of clinical lipidology 20081001 |
| Base-induced sequential cyclization-rearrangement of enantioenriched 3-aminoalkanoates to five- and seven-membered lactams. | Chemistry, an Asian journal 20080901 |
| Drug delivery approaches to overcome bacterial resistance to beta-lactam antibiotics. | Expert opinion on drug delivery 20080901 |
| Novel syntheses of azetidines and azetidinones. | Chemical reviews 20080901 |
| Ethyl 1'-[1-(4-methoxyphenyl)-3-phenoxy-4-phenylazetidin-1-yl]-1,3-dioxo-2',3',5',6',7',7a'-hexahydroindan-2-spiro-3'-1'H-pyrrolizine-2'-carboxylate. | Acta crystallographica. Section E, Structure reports online 20080901 |
| Spectroscopic characterization of the 1-substituted 3,3-diphenyl-4-(2'-hydroxyphenyl)azetidin-2-ones: application of (13)C NMR, (1)H-(13)C COSY NMR and mass spectroscopy. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080801 |
| 3-Alkenyl-2-azetidinones as fatty acid amide hydrolase inhibitors. | Bioorganic & medicinal chemistry letters 20080715 |
| Indium-mediated 1,2,4,5-hexatetraen-3-ylation of 4-acetoxy-2-azetidinones and their applications to the Diels-Alder reactions for the synthesis of 2-azetidinone derivatives. | The Journal of organic chemistry 20080704 |
| Total synthesis of (-)-kainic acid via intramolecular Michael addition: a second-generation route. | Organic letters 20080501 |
| 1-(4-Methoxy-phen-yl)-7-phenyl-3-(phenyl-selenylmeth-yl)perhydro-isoxazolo[2',3':1,2]pyrrolo[3,4-b]azetidine-6-spiro-2'-chroman-2,4'-dione. | Acta crystallographica. Section E, Structure reports online 20080501 |
| 2-[1-(4-Ethoxy-phen-yl)-2-oxo-4-styryl-azetidin-3-yl]isoindoline-1,3-dione. | Acta crystallographica. Section E, Structure reports online 20080501 |
| Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model. | Journal of medicinal chemistry 20080424 |
| Discovery of azetidinone acids as conformationally-constrained dual PPARalpha/gamma agonists. | Bioorganic & medicinal chemistry letters 20080315 |
| Anti-tubercular and anti-inflammatory activities of azetidin-2-one derivatives and their effects on the activity of Phospholipase A2. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20080301 |
| New regiocontrolled synthesis of functionalized pyrroles from 2-azetidinone-tethered allenols. | Chemistry (Weinheim an der Bergstrasse, Germany) 20080101 |
| Synthesis and Pharmacological Evaluation of Azetidin-2-ones and Thiazolidin-4-ones Encompassing Benzothiazole. | Indian journal of pharmaceutical sciences 20080101 |
| Antibacterial Activity of Barringtonia acutangula against Selected Urinary Tract Pathogens. | Indian journal of pharmaceutical sciences 20080101 |
| Synthesis and biological activity of N-substituted-3-chloro-2-azetidinones. | Molecules (Basel, Switzerland) 20071112 |
| Synthesis of novel N-(4-ethoxyphenyl) azetidin-2-ones and their oxidative N-deprotection by ceric ammonium nitrate. | Molecules (Basel, Switzerland) 20071025 |
| A minimalistic approach to identify substrate binding features in B1 Metallo-beta-lactamases. | Bioorganic & medicinal chemistry letters 20070915 |
| Inhibitory effect by new monocyclic 4-alkyliden-beta-lactam compounds on human platelet activation. | Platelets 20070801 |
| Synthesis of 3-[4'-(p-chlorophenyl)-thiazol-2'-yl]-2-[(substituted azetidinone/thiazolidinone)-aminomethyl]-6-bromoquinazolin-4-ones as anti-inflammatory agent. | Bioorganic & medicinal chemistry 20070415 |
| Interaction of beta-lactam carbenes with aryl isonitriles: an unprecedented rearrangement of 2-azetidinonylidene indoles to delta-carbolinones. | The Journal of organic chemistry 20070330 |
| Azetidinones as vasopressin V1a antagonists. | Bioorganic & medicinal chemistry 20070301 |
| Two new antifungal alkaloids produced by Streptoverticillium morookaense. | The Journal of antibiotics 20070301 |
| In vivo responsiveness to ezetimibe correlates with niemann-pick C1 like-1 (NPC1L1) binding affinity: Comparison of multiple species NPC1L1 orthologs. | Molecular pharmacology 20070101 |
| Ezetimibe analogs with a reorganized azetidinone ring: Design, synthesis, and evaluation of cholesterol absorption inhibitions. | Bioorganic & medicinal chemistry letters 20070101 |
| Indium-mediated selective introduction of a 1,3-butadien-2-yl group at the C4-position in 2-azetidinones and application of 1,3-diene-tethered 2-azetidinones in the Diels-Alder reaction. | Chemistry (Weinheim an der Bergstrasse, Germany) 20070101 |
| A theoretical proposal for the synthesis of carbapenems from 4-(2-propynyl)azetidinones promoted by [W(CO)5] as an alternative to the Ag+-assisted process. | Chemistry (Weinheim an der Bergstrasse, Germany) 20061016 |
| A theoretical study of rhodium(I) catalyzed carbonylative ring expansion of aziridines to beta-lactams: crucial activation of the breaking C-N bond by hyperconjugation. | The Journal of organic chemistry 20060915 |
| Structures of (S)-(-)-4-oxo-2-azetidinecarboxylic acid and 3-azetidinecarboxylic acid from powder synchrotron diffraction data. | Acta crystallographica. Section B, Structural science 20060801 |
| An ab initio study on the allene-isocyanic acid and ketene-vinylimine [2 + 2] cycloaddition reaction paths. | The journal of physical chemistry. A 20060316 |
| Synthesis of strained tricyclic beta-lactams by intramolecular [2+2] cycloaddition reactions of 2-azetidinone-tethered enallenols: control of regioselectivity by selective alkene substitution. | Chemistry (Weinheim an der Bergstrasse, Germany) 20060201 |
| The polymer-supported and combinatorial synthesis of beta-lactam compounds: an update. | Mini reviews in medicinal chemistry 20060101 |
| Rabbit small intestine does not contain an annexin II/caveolin 1 complex as a target for 2-azetidinone cholesterol absorption inhibitors. | Biochimica et biophysica acta 20060101 |
| Nitrenium ion azaspirocyclization-spirodienone cleavage: a new synthetic strategy for the stereocontrolled preparation of highly substituted lactams and N-hydroxy lactams. | The Journal of organic chemistry 20051209 |
| Synthesis of 2-azetidinones from 2-diazo-1, 2-diarylethanones and N-(2-thienylidene)imines as possible antimicrobial agents. | Farmaco (Societa chimica italiana : 1989) 20050901 |
| The indium-mediated selective introduction of allenyl and propargyl groups at the C4-position of 2-azetidinones and the AuCl3-catalyzed cyclization of 4-allenyl-2-azetidinones. | Angewandte Chemie (International ed. in English) 20050311 |
| 3,4-disubstituted azetidinones as selective inhibitors of the cysteine protease cathepsin K. Exploring P3 elements for potency and selectivity. | Bioorganic & medicinal chemistry letters 20050301 |
| Synthesis and anti-tubulin activity of a 3'-(4-azidophenyl)-3'-dephenylpaclitaxel photoaffinity probe. | Journal of medicinal chemistry 20041216 |
| Ketopyrrolidines and ketoazetidines as potent dipeptidyl peptidase IV (DPP IV) inhibitors. | Bioorganic & medicinal chemistry letters 20041115 |
| Ezetimibe--a new cholesterol-lowering drug. | Drug and therapeutics bulletin 20040901 |
| Beta-lactams as versatile synthetic intermediates for the preparation of heterocycles of biological interest. | Current medicinal chemistry 20040701 |
| Kinetics and mechanism of hydrolysis of N-acyloxymethyl derivatives of azetidin-2-one. | The Journal of organic chemistry 20040514 |
| Examination of the 1,4-disubstituted azetidinone ring system as a template for combretastatin A-4 conformationally restricted analogue design. | Bioorganic & medicinal chemistry letters 20040503 |
| Solid-phase synthesis and SAR of 4-carboxy-2-azetidinone mechanism-based tryptase inhibitors. | Bioorganic & medicinal chemistry letters 20040503 |
| Regioselective Baeyer-Villiger oxidation in 4-carbonyl-2-azetidinone series: a revisited route toward carbapenem precursor. | The Journal of organic chemistry 20040430 |
| Functionalized macrocycles from functionalized tetra-amines: pendent-arm macrocycles derived from dichloropivalic acid. | Inorganic chemistry 20040308 |
| Synthesis of optically pure highly functionalized gamma-lactams via 2-azetidinone-tethered iminophosphoranes. | The Journal of organic chemistry 20040206 |
| Synthesis of antitumor 6-alkylidenepenicillanate sulfones and related 3-alkylidene-2-azetidinones. | Bioorganic & medicinal chemistry letters 20040105 |
| Synthesis and evaluation of N1/C4-substituted beta-lactams as PPE and HLE inhibitors. | Bioorganic & medicinal chemistry 20040102 |
| Synthesis of cryptophycins via an N-acyl-beta-lactam macrolactonization. | The Journal of organic chemistry 20031212 |
| Design of beta-lactams with mechanism based nonantibacterial activities. | Current medicinal chemistry 20030901 |
| Ezetimibe for management of hypercholesterolemia. | The Annals of pharmacotherapy 20030601 |
| Crystal structure of 3,3-dichloro-N-p-methoxyphenyl-4-(2-phenylstryl)-2-azetidinone. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20030601 |
| Synthesis of a biotin-tagged photoaffinity probe of 2-azetidinone cholesterol absorption inhibitors. | Bioorganic & medicinal chemistry 20030417 |
| Catalysts with mixed ligands on immobilized supports. Electronic and steric advantages. | Organic letters 20030220 |
| Ezetimibe. | American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101 |
| Exploring solid-phase approaches for the preparation of new beta-lactams from amino acids. | Molecular diversity 20030101 |
| beta-Lactam allergenic determinants: fine structural recognition of a cross-reacting determinant on benzylpenicillin and cephalothin. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20021101 |
| Efficient and highly stereoselective synthesis of a beta-lactam inhibitor of the serine protease prostate-specific antigen. | Bioorganic & medicinal chemistry 20020601 |
| A stereoselective synthesis of BMS-262084, an azetidinone-based tryptase inhibitor. | The Journal of organic chemistry 20020531 |
| General approach for the stereocontrolled construction of the beta-lactam ring in amino acid-derived 4-alkyl-4-carboxy-2-azetidinones. | The Journal of organic chemistry 20020531 |
| SmI(2)-mediated cyclizations of derivatized beta-lactams for the highly diastereoselective construction of functionalized prolines. | The Journal of organic chemistry 20020419 |
| Water-assisted alkaline hydrolysis of monobactams: a theoretical study. | Chemistry (Weinheim an der Bergstrasse, Germany) 20020215 |
| Synthesis of iodinated biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors. | Bioorganic & medicinal chemistry letters 20020211 |
| Synthesis of fluorescent biochemical tools related to the 2-azetidinone class of cholesterol absorption inhibitors. | Bioorganic & medicinal chemistry letters 20020211 |
| Cholesterol absorption inhibitors for the treatment of hypercholesterolaemia. | Drugs 20020101 |
| Synthesis of ferrocene-substituted 2-azetidinones. | The Journal of organic chemistry 20011228 |
| Design, synthesis and pharmacological evaluation of 3-benzylazetidine-2-one-based human chymase inhibitors. | Bioorganic & medicinal chemistry 20011101 |
| beta-Lactam derivatives as enzyme inhibitors: derivatives of (E)-2-[(RS)-1-(4-methoxyphenyl)-2-oxo-4-phenylazetidin-3-ylidene]propionic acid. | Die Pharmazie 20010901 |
| Metal-promoted allylation, propargylation, or allenylation of azetidine-2,3-diones in aqueous and anhydrous media. Application to the asymmetric synthesis of densely functionalized 3-substituted 3-hydroxy-beta-lactams. | The Journal of organic chemistry 20010727 |
| Crystal structure of 3,3-dichloro-N-p-methoxyphenyl-4-(2-phenylstryl)-2-azetidinone. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20010701 |
| Entry to new conformationally constrained amino acids. First synthesis of 3-unsubstituted 4-alkyl-4-carboxy-2-azetidinone derivatives via an intramolecular N(alpha)-C(alpha)-cyclization strategy. | The Journal of organic chemistry 20010518 |
| Design, synthesis, and proposed active site binding analysis of monocyclic 2-azetidinone inhibitors of prostate specific antigen. | Journal of medicinal chemistry 20010510 |
| Design, synthesis and stability of N-acyloxymethyl- and N-aminocarbonyloxymethyl-2-azetidinones as human leukocyte elastase inhibitors. | Bioorganic & medicinal chemistry letters 20010423 |
| Fine structural recognition specificities of IgE antibodies distinguishing amoxicilloyl and amoxicillanyl determinants in allergic subjects. | Journal of molecular recognition : JMR 20010101 |
| Synthesis of trans-4-aryl-3-(omega-chloroalkyl) -2-azetidinones. | Mededelingen (Rijksuniversiteit te Gent. Fakulteit van de Landbouwkundige en Toegepaste Biologische Wetenschappen) 20010101 |