2-Amino-6-chloropurine
| Title | Journal |
|---|---|
| Tautomeric purine forms of 2-amino-6-chloropurine (N9H10 and N7H10): structures, vibrational assignments, NBO analysis, hyperpolarizability, HOMO-LUMO study using B3 based density functional calculations. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20121001 |
| In vitro metabolism of BIIB021, an inhibitor of heat shock protein 90, in liver microsomes and hepatocytes of rats, dogs, and humans and recombinant human cytochrome P450 isoforms. | Drug metabolism and disposition: the biological fate of chemicals 20120401 |
| Stereoselective synthesis of PSI-352938: a β-D-2'-deoxy-2'-α-fluoro-2'-β-C-methyl-3',5'-cyclic phosphate nucleotide prodrug for the treatment of HCV. | The Journal of organic chemistry 20110520 |
| Phosphonate analogues of cyclopropavir phosphates and their E-isomers. Synthesis and antiviral activity. | Bioorganic & medicinal chemistry 20090601 |
| (Z)- and (E)-2-(1,2-dihydroxyethyl)methylenecyclopropane analogues of 2'-deoxyadenosine and 2'-deoxyguanosine. Synthesis of all stereoisomers, absolute configuration, and antiviral activity. | Journal of medicinal chemistry 20090528 |
| Additive Pummerer reaction of 3,5-O-(di-tert-butyl)silylene-4-thiofuranoid glycal: a high-yield and beta-selective entry to 4'-thioribonucleosides. | The Journal of organic chemistry 20090320 |
| 2-Position base-modified analogues of adenophostin A as high-affinity agonists of the D-myo-inositol trisphosphate receptor: in vitro evaluation and molecular modeling. | The Journal of organic chemistry 20080307 |
| Synthesis of altritol nucleoside phosphoramidites for oligonucleotide synthesis. | Current protocols in nucleic acid chemistry 20070901 |
| The screening and characterization of 6-aminopurine-based xanthine oxidase inhibitors. | Bioorganic & medicinal chemistry 20070515 |
| Synthesis of 'reversed' methylenecyclopropane analogues of antiviral phosphonates. | Nucleosides, nucleotides & nucleic acids 20070101 |
| Fluoroanalogues of anti-cytomegalovirus agent cyclopropavir: synthesis and antiviral activity of (E)- and (Z)-9-{[2,2-bis(hydroxymethyl)-3-fluorocyclopropylidene]methyl}-adenines and guanines. | Nucleosides, nucleotides & nucleic acids 20070101 |
| Synthesis of 2,2,3-tris(hydroxymethyl)methylenecyclopropane analogues of nucleosides. | Nucleosides, nucleotides & nucleic acids 20070101 |
| Asymmetric synthesis of novel apio carbocyclic nucleoside analogues as potential antiviral and antitumor agent. | Nucleosides, nucleotides & nucleic acids 20070101 |
| Lead compounds for antimalarial chemotherapy: purine base analogs discriminate between human and P. falciparum 6-oxopurine phosphoribosyltransferases. | Journal of medicinal chemistry 20061214 |
| Efficient N-arylation and N-alkenylation of the five DNA/RNA nucleobases. | The Journal of organic chemistry 20061124 |
| 9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1. | Journal of medicinal chemistry 20061005 |
| Oxanosine is a substrate of adenosine deaminase. Implications for the quest for a toxicological marker for nitrosation activity. | Chemical research in toxicology 20051201 |
| Synthesis and preliminary biological evaluation of O6-[4-(2-[18F]fluoroethoxymethyl)benzyl]guanine as a novel potential PET probe for the DNA repair protein O6-alkylguanine-DNA alkyltransferase in cancer chemotherapy. | Bioorganic & medicinal chemistry 20051015 |
| Synthesis of 9-alkyl and 9-heteroalkyl substituted 2-amino-6-guanidinopurines and their influence on the NO-production in macrophages. | Bioorganic & medicinal chemistry 20050415 |
| Stereoselective synthesis of 9-beta-d-arabianofuranosyl guanine and 2-amino-9-(beta-d-arabianofuranosyl)purine. | Bioorganic & medicinal chemistry letters 20050201 |
| Synthesis of 2-amino-6-(4-[11C]methoxyphenylthio)-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) ester as a novel potential PET gene reporter probe for HBV and HSV-tk in cancers. | Bioorganic & medicinal chemistry 20050117 |
| Conformationally constrained purine mimics. Incorporation of adenine and guanine into spirocyclic nucleosides. | The Journal of organic chemistry 20040820 |
| Syntheses and base-pairing properties of locked nucleic acid nucleotides containing hypoxanthine, 2,6-diaminopurine, and 2-aminopurine nucleobases. | The Journal of organic chemistry 20040528 |
| Synthesis and antiviral activity of (Z)- and (E)-2,2-[bis(hydroxymethyl)cyclopropylidene]methylpurines and -pyrimidines: second-generation methylenecyclopropane analogues of nucleosides. | Journal of medicinal chemistry 20040129 |
| Synthesis of base substituted 2-hydroxy-3-(purin-9-yl)-propanoic acids and 4-(purin-9-yl)-3-butenoic acids. | Nucleosides, nucleotides & nucleic acids 20031201 |
| Facilitation of addition-elimination reactions in pyrimidines and purines using trifluoroacetic acid in trifluoroethanol. | Chemical communications (Cambridge, England) 20031121 |
| Synthesis and preliminary biological evaluation of radiolabeled O6-benzylguanine derivatives, new potential PET imaging agents for the DNA repair protein O6-alkylguanine-DNA alkyltransferase in breast cancer. | Nuclear medicine and biology 20030501 |
| Structure-activity relationships of (S,Z)-2-aminopurine methylenecyclopropane analogues of nucleosides. Variation of purine-6 substituents and activity against herpesviruses and hepatitis B virus. | Journal of medicinal chemistry 20030410 |
| Synthesis of 7-hydroxy(phenyl)ethylguanines by alkylation of 2-amino-6-chloropurine with allyl-protected bromohydrins. | Organic letters 20030306 |
| Synthesis of (Z)-(2,3-bis-hydroxymethyl)methylenecyclopropane analogues of purine nucleosides. | Nucleosides, nucleotides & nucleic acids 20030301 |
| Efficient syntheses of 2-chloro-2'-deoxyadenosine (cladribine) from 2'-deoxyguanosine(1). | The Journal of organic chemistry 20030207 |
| Three 2-aminopurine derivatives. | Acta crystallographica. Section C, Crystal structure communications 20030101 |
| Structure-activity relationships of 2'-fluoro-2',3'-unsaturated D-nucleosides as anti-HIV-1 agents. | Journal of medicinal chemistry 20020314 |
| Synthesis of 2-alkyl-substituted-N6-methyladenine derivatives as potential adenosine receptor ligand. | Archives of pharmacal research 20011201 |
| Methylene-gem-difluorocyclopropane analogues of nucleosides: synthesis, cyclopropene-methylenecyclopropane rearrangement, and biological activity. | Journal of medicinal chemistry 20011108 |
| Structure-activity relationships for the binding of ligands to xanthine or guanine phosphoribosyl-transferase from Toxoplasma gondii. | Biochemical pharmacology 19951109 |