Home Other Building Blocks 2-Amino-1,3,4-thiadiazole

2-Amino-1,3,4-thiadiazole

CAS No.:
4005-51-0
Catalog Number:
AG00332R
Molecular Formula:
C2H3N3S
Molecular Weight:
101.1303
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$13
- +
25g
98%
In Stock USA
United States
$25
- +
100g
98%
In Stock USA
United States
$63
- +
500g
98%
In Stock USA
United States
$188
- +
Product Description
Catalog Number:
AG00332R
Chemical Name:
2-Amino-1,3,4-thiadiazole
CAS Number:
4005-51-0
Molecular Formula:
C2H3N3S
Molecular Weight:
101.1303
MDL Number:
MFCD00003107
IUPAC Name:
1,3,4-thiadiazol-2-amine
InChI:
InChI=1S/C2H3N3S/c3-2-5-4-1-6-2/h1H,(H2,3,5)
InChI Key:
QUKGLNCXGVWCJX-UHFFFAOYSA-N
SMILES:
Nc1nncs1
EC Number:
223-657-7
UNII:
6L41AOK74P
NSC Number:
4728
Properties
Complexity:
48.1  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
101.005g/mol
Formal Charge:
0
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
101.127g/mol
Monoisotopic Mass:
101.005g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
80A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.6  
Literature
Title Journal
2-Amino-1,3,4-thiadiazole derivative (FABT) inhibits the extracellular signal-regulated kinase pathway and induces cell cycle arrest in human non-small lung carcinoma cells. Bioorganic & medicinal chemistry letters 20120901
5-(Thio-phen-2-ylmeth-yl)-1,3,4-thia-diazol-2-amine. Acta crystallographica. Section E, Structure reports online 20120501
Investigation of trypanothione reductase inhibitory activity by 1,3,4-thiadiazolium-2-aminide derivatives and molecular docking studies. Bioorganic & medicinal chemistry 20120301
4-(3,5-Dioxo-10-oxa-4-aza-tricyclo-[5.2.1.0]decan-4-yl)-10-oxa-4-aza-tricyclo-[5.2.1.0]decane-3,5-dione. Acta crystallographica. Section E, Structure reports online 20120201
The in vivo activity of 1,3,4-thiadiazolium-2-aminide compounds in the treatment of cutaneous and visceral leishmaniasis. The Journal of antimicrobial chemotherapy 20120101
catena-Poly[(μ-2-amino-1,3,4-thia-diazole-κN:N)di-μ-chlorido-cadmium]. Acta crystallographica. Section E, Structure reports online 20110801
Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase. Journal of medicinal chemistry 20110113
Spectroscopic studies of intramolecular proton transfer in 2-(4-fluorophenylamino)-5-(2,4-dihydroxybenzeno)-1,3,4-thiadiazole. Journal of fluorescence 20110101
The activity of a new 2-amino-1,3,4-thiadiazole derivative 4ClABT in cancer and normal cells. Folia histochemica et cytobiologica 20110101
(14)N NQR, (1)H NMR and DFT/QTAIM study of hydrogen bonding and polymorphism in selected solid 1,3,4-thiadiazole derivatives. Physical chemistry chemical physics : PCCP 20101028
Selective determination of homocysteine at physiological pH using nanostructured film of aminothiadiazole modified electrode. Bioelectrochemistry (Amsterdam, Netherlands) 20101001
catena-Poly[[diaqua-manganese(II)]-μ-7-oxabicyclo-[2.2.1]heptane-2,3-dicarboxyl-ato]. Acta crystallographica. Section E, Structure reports online 20100601
Simultaneous determination of ascorbic acid, dopamine, uric acid and xanthine using a nanostructured polymer film modified electrode. Talanta 20100315
N,N-Bis(2,6-difluoro-benz-yl)-1,3,4-thia-diazol-2-amine. Acta crystallographica. Section E, Structure reports online 20090901
rac-7-Oxabicyclo-[2.2.1]heptane-2,3-dicarboxylic acid-2-amino-1,3,4-thia-diazole-water (1/1/1). Acta crystallographica. Section E, Structure reports online 20090701
Amide derivatives with pyrazole carboxylic acids of 5-amino-1,3,4-thiadiazole 2-sulfonamide as new carbonic anhydrase inhibitors: synthesis and investigation of inhibitory effects. Journal of enzyme inhibition and medicinal chemistry 20081201
5,5'-Diethyl-2,2'-(triazene-1,3-di-yl)di-1,3,4-thia-diazole. Acta crystallographica. Section E, Structure reports online 20081101
Anticancer, neuroprotective activities and computational studies of 2-amino-1,3,4-thiadiazole based compound. Bioorganic & medicinal chemistry 20070501
[2-(2,4-Dihydroxyphenyl)-1,3,4-thiadiazole analogues: antifungal activity in vitro against Candida species]. Bioorganicheskaia khimiia 20070101
Probing Aspergillus niger glucose oxidase with pentacyanoferrate(III) aza- and thia-complexes. Journal of inorganic biochemistry 20061001
Synthesis and spectroscopic studies of new Schiff bases. Molecules (Basel, Switzerland) 20060317
2-Amino-5-trifluoromethyl-1,3,4-thiadiazole and a redetermination of 2-amino-1,3,4-thiadiazole, both at 120 K: chains of edge-fused R(2)(2)(8) and R(4)(4)(10) rings, and sheets of R(2)(2)(8) and R(6)(6)(20) rings. Acta crystallographica. Section C, Crystal structure communications 20060101
Spectrophotometric and electrical studies of charge transfer complexes of 2-amino-1,3,4-thiadiazole with pi-acceptors. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051101
Cytotoxic effect of a new 1,3,4-thiadiazolium mesoionic compound (MI-D) on cell lines of human melanoma. British journal of cancer 20040719
Role of an aminothiazole derivative on ethanol- and thermally oxidized sunflower oil-induced toxicity. Polish journal of pharmacology 20040101
Antibacterial Role of SO(4), NO(3), C(2)O(4) and CH(3)CO(2) Anions on Cu(II) and Zn(II) Complexes of a Thiadiazole-derived Pyrrolyl Schiff Base. Metal-based drugs 20020101
2-Amino-5-methyl-1,3,4-thiadiazole and 2-amino-5-ethyl-1,3,4-thiadiazole. Acta crystallographica. Section C, Crystal structure communications 20011001
Biological evaluation of hepatitis C virus helicase inhibitors. Bioorganic & medicinal chemistry letters 20010709
Antibacterial Co(II), Cu(II), Ni(II) and Zn(II) Complexes of Thiadiazoles Schiff Bases. Metal-based drugs 20010101
DNA synthesis inhibition, cytotoxicity and their relationship to teratogenesis following administration of a nicotinamide antagonist, aminothiadiazole, to pregnant rats. Journal of embryology and experimental morphology 19730801
Properties