Home Aminos 2,4-Diamino-6-(hydroxymethyl)pteridine

2,4-Diamino-6-(hydroxymethyl)pteridine

CAS No.:
945-24-4
Catalog Number:
AG0032ZV
Molecular Formula:
C7H8N6O
Molecular Weight:
192.1780
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
98%
1 week
United States
$94
- +
Product Description
Catalog Number:
AG0032ZV
Chemical Name:
2,4-Diamino-6-(hydroxymethyl)pteridine
CAS Number:
945-24-4
Molecular Formula:
C7H8N6O
Molecular Weight:
192.1780
MDL Number:
MFCD00006711
IUPAC Name:
(2,4-diaminopteridin-6-yl)methanol
InChI:
InChI=1S/C7H8N6O/c8-5-4-6(13-7(9)12-5)10-1-3(2-14)11-4/h1,14H,2H2,(H4,8,9,10,12,13)
InChI Key:
CYNARAWTVHQHDI-UHFFFAOYSA-N
SMILES:
OCc1cnc2c(n1)c(N)nc(n2)N
EC Number:
213-412-2
UNII:
1RU16O4RO0
Properties
Complexity:
203  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
192.076g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
192.182g/mol
Monoisotopic Mass:
192.076g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
124A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.7  
Literature
Title Journal
Resistance of a rodent malaria parasite to a thymidylate synthase inhibitor induces an apoptotic parasite death and imposes a huge cost of fitness. PloS one 20110101
Plasmodium berghei: lack of antimalarial activity of an analogue of folate precursor, 2,4-diamino-6-hydroxymethylpteridine in a mouse model. Experimental parasitology 20081101
Prediction of genotoxicity of chemical compounds by statistical learning methods. Chemical research in toxicology 20050601
Determination of the chiral and achiral related substances of methotrexate by cyclodextrin-modified micellar electrokinetic chromatography. Electrophoresis 20040801
Photohydrolysis of methotrexate produces pteridine, which induces poly-G-specific DNA damage through photoinduced electron transfer. Photochemistry and photobiology 20021101
Design, synthesis, computational prediction, and biological evaluation of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii. Journal of medicinal chemistry 20010719
Virtual combinatorial syntheses and computational screening of new potential anti-herpes compounds. Journal of medicinal chemistry 19990826
Properties