Home Other Building Blocks 2-(4-Chlorophenoxy)-2-methylpropanoic acid

2-(4-Chlorophenoxy)-2-methylpropanoic acid

CAS No.:
882-09-7
Catalog Number:
AG0032US
Molecular Formula:
C10H11ClO3
Molecular Weight:
214.6455
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$13
- +
25g
98%
In Stock USA
United States
$32
- +
100g
98%
In Stock USA
United States
$100
- +
500g
98%
In Stock USA
United States
$400
- +
Product Description
Catalog Number:
AG0032US
Chemical Name:
2-(4-Chlorophenoxy)-2-methylpropanoic acid
CAS Number:
882-09-7
Molecular Formula:
C10H11ClO3
Molecular Weight:
214.6455
MDL Number:
MFCD00004192
IUPAC Name:
2-(4-chlorophenoxy)-2-methylpropanoic acid
InChI:
InChI=1S/C10H11ClO3/c1-10(2,9(12)13)14-8-5-3-7(11)4-6-8/h3-6H,1-2H3,(H,12,13)
InChI Key:
TXCGAZHTZHNUAI-UHFFFAOYSA-N
SMILES:
OC(=O)C(Oc1ccc(cc1)Cl)(C)C
EC Number:
212-925-9
UNII:
53PF01Q249
Properties
Complexity:
207  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
214.04g/mol
Formal Charge:
0
Heavy Atom Count:
14  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
214.645g/mol
Monoisotopic Mass:
214.04g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
46.5A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.6  
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Determination of etofibrate, fenofibrate, and atorvastatin in pharmaceutical preparations and plasma using differential pulse polarographic and square wave voltammetric techniques. Journal of AOAC International 20080101
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Preliminary studies into the effects of the human pharmaceutical Clofibric acid on sperm parameters in adult Fathead minnow. Aquatic toxicology (Amsterdam, Netherlands) 20070815
Liquid chromatography-(tandem) mass spectrometry for the follow-up of the elimination of persistent pharmaceuticals during wastewater treatment applying biological wastewater treatment and advanced oxidation. Journal of chromatography. A 20070810
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Effect of chrysin and natural coumarins on UGT1A1 and 1A6 activities in rat and human hepatocytes in primary culture. Planta medica 20070701
Analytical development for analysis of pharmaceuticals in water samples by SPE and GC-MS. Analytical and bioanalytical chemistry 20070601
[Metabolically designed treatments: from biochemistry to the vessel lining]. La Revue de medecine interne 20070601
Elimination of selected acidic pharmaceuticals from municipal wastewater by an activated sludge system and membrane bioreactors. Environmental science & technology 20070515
Studies on the metabolism of tolmetin to the chemically reactive acyl-coenzyme A thioester intermediate in rats. Drug metabolism and disposition: the biological fate of chemicals 20070501
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The clinical significance of the size of low-density-lipoproteins and the modulation of subclasses by fibrates. Current medical research and opinion 20070501
Determination of anti-inflammatory drugs and estrogens in water by HPLC with UV detection. Journal of separation science 20070501
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Hypertriglyceridemia: its etiology, effects and treatment. CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20070410
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Stearoyl-CoA desaturase activity is elevated by the suppression of its degradation by clofibric acid in the liver of rats. Journal of pharmacological sciences 20070401
The role of PPAR-alpha agonists in the prevention of CVD in diabetes. Current diabetes reports 20070401
Clofibric acid, a peroxisome proliferator-activated receptor alpha ligand, inhibits growth of human ovarian cancer. Molecular cancer therapeutics 20070401
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Statins and the risk of pneumonia: a population-based, nested case-control study. Pharmacotherapy 20070301
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Fibrates upregulate TRB3 in lymphocytes independent of PPAR alpha by augmenting CCAAT/enhancer-binding protein beta (C/EBP beta) expression. Molecular immunology 20070201
LC-MS analysis and environmental risk of lipid regulators. Analytical and bioanalytical chemistry 20070201
Analysis of pharmaceuticals in wastewater and removal using a membrane bioreactor. Analytical and bioanalytical chemistry 20070201
Removal of pharmaceutical residues in a pilot wastewater treatment plant. Analytical and bioanalytical chemistry 20070201
Ultrastructural effects of pharmaceuticals (carbamazepine, clofibric acid, metoprolol, diclofenac) in rainbow trout (Oncorhynchus mykiss) and common carp (Cyprinus carpio). Analytical and bioanalytical chemistry 20070201
Human pharmaceuticals, antioxidants, and plasticizers in wastewater treatment plant and water reclamation plant effluents. Water environment research : a research publication of the Water Environment Federation 20070201
High performance liquid chromatographic determination of etofibrate and its hydrolysis products. Journal of pharmaceutical and biomedical analysis 20070104
Simultaneous quantification of polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), and pharmaceuticals and personal care products (PPCPs) in Mississippi river water, in New Orleans, Louisiana, USA. Chemosphere 20070101
Degradation of clofibric acid in acidic aqueous medium by electro-Fenton and photoelectro-Fenton. Chemosphere 20070101
Paradoxical HDL-C reduction during rosiglitazone and fibrate treatment. Diabetic medicine : a journal of the British Diabetic Association 20070101
A light- and electron-microscope study of hepatocytes of rats fed different diets. Comptes rendus biologies 20070101
Dual PPAR alpha/gamma agonists: promises and pitfalls in type 2 diabetes. American journal of therapeutics 20070101
Management of dyslipidemia in the metabolic syndrome: recommendations of the Spanish HDL-Forum. American journal of cardiovascular drugs : drugs, devices, and other interventions 20070101
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Clofibrate treatment in pigs: effects on parameters critical with respect to peroxisome proliferator-induced hepatocarcinogenesis in rodents. BMC pharmacology 20070101
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[Influence of combined, hypolipemic therapy on lipids and non-lipid atherosclerosis risk factors]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20070101
[Pleiotropic effects of fibric acid derivatives (Lipanthyl-200) among patients with metabolic syndrome]. Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20070101
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Effects of statins, fibrates, rosuvastatin, and ezetimibe beyond cholesterol: the modulation of LDL size and subclasses in high-risk patients. Advances in therapy 20070101
Lipid-modifying therapy and attainment of cholesterol goals in Hungary: the return on expenditure achieved for lipid therapy (REALITY) study. Clinical drug investigation 20070101
An investigation of the effects of lipid-lowering medications: genome-wide linkage analysis of lipids in the HyperGEN study. BMC genetics 20070101
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Targeting high-density lipoprotein cholesterol in the management of cardiovascular disease. The American heart hospital journal 20070101
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Aryloxoalcanoic compounds induce resistance to antibiotic therapy in urinary tract infection caused by Escherichia coli. FEMS immunology and medical microbiology 20061201
Regulation of hepatic cholesterol synthesis by a novel protein (SPF) that accelerates cholesterol biosynthesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061201
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9-cis beta-carotene-rich powder of the alga Dunaliella bardawil increases plasma HDL-cholesterol in fibrate-treated patients. Atherosclerosis 20061101
Human UDP-glucuronosyltransferase (UGT)1A3 enzyme conjugates chenodeoxycholic acid in the liver. Hepatology (Baltimore, Md.) 20061101
20-HETE and salt-sensitivity of blood pressure a novel emerging concept. American journal of hypertension 20061101
Activation of peroxisome proliferator-activated receptor-gamma (PPARgamma) induces cell death through MAPK-dependent mechanism in osteoblastic cells. Toxicology and applied pharmacology 20060901
Nucleophilic group transfer reactivity for fibric acid derived drug molecules. Journal of pharmaceutical sciences 20060901
Fibrate therapy in patients with metabolic syndrome and diabetes mellitus. Current atherosclerosis reports 20060901
A critical role for peroxisomal proliferator-activated receptor-alpha nuclear receptors in the development of cardiomyocyte degeneration and necrosis. The American journal of pathology 20060901
Seasonality effects on pharmaceuticals and s-triazine herbicides in wastewater effluent and surface water from the Canadian side of the upper Detroit River. Environmental toxicology and chemistry 20060901
The interference of pharmaceuticals with endogenous and xenobiotic metabolizing enzymes in carp liver: an in-vitro study. Environmental science & technology 20060815
Cloning, tissue expression, and regulation of beagle dog CYP4A genes. Toxicological sciences : an official journal of the Society of Toxicology 20060801
Fibric acid derivatives in cardiovascular disease prevention: results from the large clinical trials. Current opinion in lipidology 20060801
Decrease in triglyceride level by bezafibrate is related to reduction of recurrent coronary events: a Bezafibrate Infarction Prevention substudy. Coronary artery disease 20060801
Clofibrate treatment promotes branched-chain amino acid catabolism and decreases the phosphorylation state of mTOR, eIF4E-BP1, and S6K1 in rat liver. Life sciences 20060717
Effects of ciprofibrate on testicular and adrenal steroidogenic enzymes in the rat. Reproductive toxicology (Elmsford, N.Y.) 20060701
Trace-level determination of pharmaceutical residues by LC-MS/MS in natural and treated waters. A pilot-survey study. Analytical and bioanalytical chemistry 20060701
Peroxisome proliferator-activated receptors in vascular biology-molecular mechanisms and clinical implications. Vascular pharmacology 20060701
Dyslipidaemia, hypercoagulability and the metabolic syndrome. Current vascular pharmacology 20060701
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N-3 fatty acid supplementation decreases plasma homocysteine in diabetic dyslipidemia treated with statin-fibrate combination. The Journal of nutritional biochemistry 20060601
Cytochrome P450 gene induction in rats ex vivo assessed by quantitative real-time reverse transcriptase-polymerase chain reaction (TaqMan). Drug metabolism and disposition: the biological fate of chemicals 20060601
Metabolomic study of cisplatin-induced nephrotoxicity. Kidney international 20060601
Ciprofibrate increases paraoxonase activity in patients with metabolic syndrome. British journal of clinical pharmacology 20060601
[Nuclear receptors PPARalpha]. Vnitrni lekarstvi 20060601
PRIC320, a transcription coactivator, isolated from peroxisome proliferator-binding protein complex. Biochemical and biophysical research communications 20060505
Separation of fibrate-type antihyperlipidemic drugs by capillary electrophoresis and their quantitation in pharmaceuticals. Journal of pharmaceutical and biomedical analysis 20060503
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Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Apolipoproteins AI and B as therapeutic targets. Journal of internal medicine 20060501
Field of confusion: future prospects for fibrate therapy in cardiovascular disease. Current atherosclerosis reports 20060501
Bioactivation of carboxylic acid compounds by UDP-Glucuronosyltransferases to DNA-damaging intermediates: role of glycoxidation and oxidative stress in genotoxicity. Chemical research in toxicology 20060501
[Intensive cholesterol lowering therapy to reduce cardiovascular risk]. Revista medica de Chile 20060501
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Fish oil increases bile acid synthesis in male patients with hypertriglyceridemia. The Journal of nutrition 20060401
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[Hyperlipidemia]. Nihon rinsho. Japanese journal of clinical medicine 20060401
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[Treatment of dyslipidemia in clinical practice]. Orvosi hetilap 20060305
The occurrence of selected pharmaceuticals in wastewater effluent and surface waters of the lower Tyne catchment. The Science of the total environment 20060301
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[Changes in serum lipids, plasma fibrinogen and other haemostatic parameters induced by ciprofibrate action in hyperlipidemic patients with and without coronary artery disease]. Investigacion clinica 20060301
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Strategies for management and treatment of dyslipidemia in HIV/AIDS. AIDS care 20060201
Preliminary risk assessment of the lipid-regulating pharmaceutical clofibric acid, for three estuarine species. Environmental research 20060201
Management of hyperlipidemia: new LDL-C targets for persons at high-risk for cardiovascular events. Medical science monitor : international medical journal of experimental and clinical research 20060201
'Anti-inflammatory' drugs and their effects on type 2 diabetes. Diabetes technology & therapeutics 20060201
Effects of widely used pharmaceuticals and a detergent on oxidative stress biomarkers of the crustacean Artemia parthenogenetica. Chemosphere 20060101
Anti-atherogenic properties of fibrates may be largely due to their anti-inflammatory effects. Medical hypotheses 20060101
Lipid testing and lipid-lowering therapy in hospitalized ischemic stroke and transient ischemic attack patients: results from a statewide stroke registry. Stroke 20060101
Assessment of compliance with lipid guidelines in an academic medical center. The Annals of pharmacotherapy 20060101
Statin/fibrate combination in patients with metabolic syndrome or diabetes: evaluating the risks of pharmacokinetic drug interactions. Expert opinion on drug safety 20060101
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The metabolic syndrome--what is it and how should it be managed? Journal of clinical hypertension (Greenwich, Conn.) 20060101
Diabetes mellitus-associated atherosclerosis: mechanisms involved and potential for pharmacological invention. American journal of cardiovascular drugs : drugs, devices, and other interventions 20060101
Flow cytometric assessment of peroxisome proliferation from frozen liver of fibrate-treated monkeys. International journal of toxicology 20060101
Mode of action of fibrates in the regulation of triglyceride and HDL-cholesterol metabolism. Drugs of today (Barcelona, Spain : 1998) 20060101
Regulatory effects of synthetic liver X receptor- and peroxisome-proliferator activated receptor agonists on sterol transport pathways in polarized cerebrovascular endothelial cells. The international journal of biochemistry & cell biology 20060101
Biologically relevant effects of mRNA amplification on gene expression profiles. BMC bioinformatics 20060101
Potential of fibrates in the treatment of fatty acid oxidation disorders: revival of classical drugs? Journal of inherited metabolic disease 20060101
2-{3-[2-(4-chlorophenyl)ethoxy]phenylthio}-2-methylpropanoic acid: a fibrate-like compound with hypolipidemic and antidiabetic activity. ChemMedChem 20060101
Gene expression profiles in rat liver slices exposed to hepatocarcinogenic enzyme inducers, peroxisome proliferators, and 17alpha-ethinylestradiol. International journal of toxicology 20060101
Effect of clofibric acid on desmin and vimentin contents in rat myocardiocytes. International journal of toxicology 20060101
Atherogenic dyslipidemia in metabolic syndrome and type 2 diabetes: therapeutic options beyond statins. Cardiovascular diabetology 20060101
[Clinical trials of statins and fibrates --a meta-analysis]. Medicinski pregled 20060101
Comparison of effects of fibrates in patients with hypertriglyceridemia. Advances in therapy 20060101
[Cardiovascular risk and possibilities of lowering it in patients with metabolic syndrome and type II diabetes mellitus. The role of fibrates]. Kardiologiia 20060101
Examination of Ligand-Dependent Coactivator Recruitment by Peroxisome Proliferator-Activated Receptor-alpha (PPARalpha). PPAR research 20060101
Cardiovascular disease: strategies for risk assessment and modification. The Journal of cardiovascular nursing 20060101
Prolonged statin administration does not act on the cell-mediated immunity of HIV-infected dyslipidemic patients treated with a steady and effective highly active antiretroviral therapy. A two-year prospective study of statin versus fibrate administration. Journal of biological regulators and homeostatic agents 20060101
[Synthesis and physico-chemical characterisation of some new derivatives of rutoside and clofibric acid]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20060101
[Continuing care of patients with cardiovascular risk in general practice: patients with dyslipidemia and their care]. Orvosi hetilap 20051225
[New studies of high dosage statins and fibrates. How is lipid lowering therapy changing? (interview by Dr. med. Dirk Einecke)]. MMW Fortschritte der Medizin 20051208
Ciprofibrate stimulates the gastrin-producing cell by acting luminally on antral PPAR-alpha. American journal of physiology. Gastrointestinal and liver physiology 20051201
Role for fibrate therapy in diabetes: evidence before FIELD. Current opinion in lipidology 20051201
Fibrate prevents cisplatin-induced proximal tubule cell death. Kidney international 20051201
Household disposal of pharmaceuticals as a pathway for aquatic contamination in the United kingdom. Environmental health perspectives 20051201
Optimal lipid modification: the rationale for combination therapy. Vascular health and risk management 20051201
Fibrates inhibit aldose reductase activity in the forward and reverse reactions. Biochemical pharmacology 20051125
Phytol directly activates peroxisome proliferator-activated receptor alpha (PPARalpha) and regulates gene expression involved in lipid metabolism in PPARalpha-expressing HepG2 hepatocytes. Biochemical and biophysical research communications 20051118
Modifying plasma low-density lipoprotein and high-density lipoprotein cholesterol: what combinations are available in the future? The American journal of cardiology 20051107
Pharmacokinetic interactions between statins and fibrates. The American journal of cardiology 20051107
Severe rhabdomyolysis during a hypersensitivity reaction to abacavir in a patient treated with ciprofibrate. AIDS (London, England) 20051104
Gene expression profiling of the PPAR-alpha agonist ciprofibrate in the cynomolgus monkey liver. Toxicological sciences : an official journal of the Society of Toxicology 20051101
Beneficial vascular and metabolic effects of peroxisome proliferator-activated receptor-alpha activators. Hypertension (Dallas, Tex. : 1979) 20051101
Hypertriglyceridemia-why, when and how should it be treated? Zeitschrift fur Kardiologie 20051101
Differential associations of statin and fibrate treatment with carotid arterial remodeling. American journal of hypertension 20051101
Therapeutical effects of PPAR agonists assessed by biomarker modulation. Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20051101
Orthogonal array designs for the optimization of liquid-liquid-liquid microextraction of nonsteroidal anti-inflammatory drugs combined with high-performance liquid chromatography-ultraviolet detection. Journal of chromatography. A 20051028
Statins and fibrates for preventing melanoma. The Cochrane database of systematic reviews 20051019
Fibrates and coronary risk reduction. Atherosclerosis 20051001
Effects of pharmaceuticals on Daphnia survival, growth, and reproduction. Chemosphere 20051001
High-density lipoprotein cholesterol: ready for prime time? Singapore medical journal 20051001
Patients with low levels of high-density lipoprotein cholesterol: to treat or not to treat? Singapore medical journal 20051001
Lipoprotein-associated phospholipase A2 as a biomarker for coronary disease and stroke. Nature clinical practice. Cardiovascular medicine 20051001
[Drug combinations: statins and fibrates]. Arquivos brasileiros de cardiologia 20051001
Clinical practice. Low HDL cholesterol levels. The New England journal of medicine 20050922
Synthesis and antiplatelet activity of thioaryloxyacids analogues of clofibric acid. European journal of medicinal chemistry 20050901
Pleiotropic effects of fibrates. Current atherosclerosis reports 20050901
Monocyte release of tumor necrosis factor-alpha and interleukin-1beta in primary type IIa and IIb dyslipidemic patients treated with statins or fibrates. Journal of cardiovascular pharmacology 20050901
Differential antiatherogenic effects of PPARalpha versus PPARgamma agonists: should we be surprised? Arteriosclerosis, thrombosis, and vascular biology 20050901
Current perspective. Diabetic vascular disease: from endothelial dysfunction to atherosclerosis. Italian heart journal : official journal of the Italian Federation of Cardiology 20050901
Synthesis, biological evaluation, and molecular modeling investigation of new chiral fibrates with PPARalpha and PPARgamma agonist activity. Journal of medicinal chemistry 20050825
Management of dyslipidemia in patients with complicated metabolic syndrome. The American journal of cardiology 20050822
Anti-inflammatory effect of fibrate protects from cisplatin-induced ARF. American journal of physiology. Renal physiology 20050801
Modulation of hepatic canalicular or basolateral transport proteins alters hepatobiliary disposition of a model organic anion in the isolated perfused rat liver. Drug metabolism and disposition: the biological fate of chemicals 20050801
Fate and mobility of pharmaceuticals in solid matrices. Chemosphere 20050801
Therapeutic roles of peroxisome proliferator-activated receptor agonists. Diabetes 20050801
Demystifying triglycerides: a practical approach for the clinician. Cleveland Clinic journal of medicine 20050801
Electrochemical determination of pharmaceuticals in spiked water samples. Journal of hazardous materials 20050715
Environmental fate of pharmaceuticals in water/sediment systems. Environmental science & technology 20050715
Behavior of selected pharmaceuticals in subsurface flow constructed wetlands: a pilot-scale study. Environmental science & technology 20050715
Expression and induction potential of cytochromes P450 in human cryopreserved hepatocytes. Drug metabolism and disposition: the biological fate of chemicals 20050701
Adiponectin receptor gene expression in human skeletal muscle cells is not regulated by fibrates and thiazolidinediones. International journal of obesity (2005) 20050701
Acute toxicity of widely used pharmaceuticals in aquatic species: Gambusia holbrooki, Artemia parthenogenetica and Tetraselmis chuii. Ecotoxicology and environmental safety 20050701
Pharmacologic augmentation of high-density lipoproteins: mechanisms of currently available and emerging therapies. Current opinion in cardiology 20050701
Effects of fibrates on human organic anion-transporting polypeptide 1B1-, multidrug resistance protein 2- and P-glycoprotein-mediated transport. Xenobiotica; the fate of foreign compounds in biological systems 20050701
Induction of overlapping genes by fasting and a peroxisome proliferator in pigs: evidence of functional PPARalpha in nonproliferating species. American journal of physiology. Regulatory, integrative and comparative physiology 20050601
Hepatic beta-oxidation and carnitine palmitoyltransferase I in neonatal pigs after dietary treatments of clofibric acid, isoproterenol, and medium-chain triglycerides. American journal of physiology. Regulatory, integrative and comparative physiology 20050601
Induction of pancreatic acinar cell proliferation by thyroid hormone. The Journal of endocrinology 20050601
Expression of cytochrome P450 enzymes in hepatic organoid reconstructed by rat small hepatocytes. Journal of gastroenterology and hepatology 20050601
[Significance of HDL cholesterol increase for the risk reduction. Methods of intervention. recommendations of experts]. Kardiologia polska 20050601
[Treatment of lipid disorders in metabolic syndrome and type 2 diabetes. The place for fibrates]. Kardiologia polska 20050601
[Influence of ACE inhibitors and fibrates on endothelial function]. Kardiologia polska 20050601
[Pleiotropic action of ACE-I and fibrates]. Kardiologia polska 20050601
[Combination pharmacotherapy therapy in the management of atherogenic dyslipidemia]. Kardiologia polska 20050601
PPAR-alpha activators suppress STAT1 inflammatory signaling in lipopolysaccharide-activated rat glia. Neuroreport 20050531
Differences in cell proliferation in rodent and human hepatic derived cell lines exposed to ciprofibrate. Cancer letters 20050526
The benefit of fibrates in the treatment of 'bad HDL-C responders to statins'. International journal of cardiology 20050525
APOE genotype, cholesterol level, lipid-lowering treatment, and dementia: the Three-City Study. Neurology 20050510
Occurrence of several acidic drugs in sewage treatment plants in Switzerland and risk assessment. Water research 20050501
The potential use of PPARalpha agonists as immunosuppressive agents. Current opinion in investigational drugs (London, England : 2000) 20050501
Regulation of palmitoyl-CoA chain elongation by clofibric acid in the liver of Zucker fa/fa rats. Lipids 20050501
Effect of different antilipidemic agents and diets on mortality: a systematic review. Archives of internal medicine 20050411
Regulation of human hepatic hydroxysteroid sulfotransferase gene expression by the peroxisome proliferator-activated receptor alpha transcription factor. Molecular pharmacology 20050401
Characterization of an acute molecular marker of nongenotoxic rodent hepatocarcinogenesis by gene expression profiling in a long term clofibric acid study. Chemical research in toxicology 20050401
Automorphosis of etiolated pea seedlings in space is simulated by a three-dimensional clinostat and the application of inhibitors of auxin polar transport. Physiologia plantarum 20050401
Rhabdomyolysis and lipid-lowering drugs. JAMA 20050323
Operational options to reduce matrix effects in liquid chromatography-electrospray ionization-mass spectrometry analysis of aqueous environmental samples. Journal of chromatography. A 20050304
Effect of lipid-lowering drug therapy on small-dense low-density lipoprotein. The Annals of pharmacotherapy 20050301
Drugs for lipids. Treatment guidelines from the Medical Letter 20050301
Cross-flow microfiltration with periodical back-washing for photocatalytic degradation of pharmaceutical and diagnostic residues-evaluation of the long-term stability of the photocatalytic activity of TiO2. Water research 20050301
Management of dyslipidemia in women in the post-hormone therapy era. Journal of general internal medicine 20050301
Beyond the statins: new therapeutic perspectives in cardiovascular disease prevention. Cardiovascular drugs and therapy 20050301
Help for your cholesterol when statins won't do. If you are one of the many, but also one of the few.. Harvard men's health watch 20050301
Determination of pharmaceutical residues in waters by solid-phase extraction and large-volume on-line derivatization with gas chromatography-mass spectrometry. Journal of chromatography. A 20050218
Pretranslational upregulation of microsomal CYP4A in rat liver by intake of a high-sucrose, lipid-devoid diet containing orotic acid. Biochemical pharmacology 20050215
[Myopathies under therapy with lipid-lowering agents]. Der Nervenarzt 20050201
Hypolipidemic drugs affect monocyte IL-1beta gene expression and release in patients with IIa and IIb dyslipidemia. Journal of cardiovascular pharmacology 20050201
Rationale for combination therapy with statin drugs in the treatment of dyslipidemia. Current atherosclerosis reports 20050201
[Dyslipidemia management in patients with impaired glucose tolerance]. Nihon rinsho. Japanese journal of clinical medicine 20050201
Have we forgotten the pivotal role of high-density lipoprotein cholesterol in atherosclerosis prevention? Current medical research and opinion 20050201
Dissociation of branched-chain alpha-keto acid dehydrogenase kinase (BDK) from branched-chain alpha-keto acid dehydrogenase complex (BCKDC) by BDK inhibitors. Journal of nutritional science and vitaminology 20050201
Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trials. Journal of the American College of Cardiology 20050118
Photocatalytic degradation of carbamazepine, clofibric acid and iomeprol with P25 and Hombikat UV100 in the presence of natural organic matter (NOM) and other organic water constituents. Water research 20050101
Management of diabetic dyslipidemia: need for reappraisal of the goals. American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101
Comparative effects of fibrates on drug metabolizing enzymes in human hepatocytes. Pharmaceutical research 20050101
[Cardiovascular system drugs. 9/12. Antilipemics--II. Fibrates and colestyramine]. Soins; la revue de reference infirmiere 20050101
AhR and PPARalpha: antagonistic effects on CYP2B and CYP3A, and additive inhibitory effects on CYP2C11. Xenobiotica; the fate of foreign compounds in biological systems 20050101
Diabetic dyslipidaemia: insights for optimizing patient management. Current medical research and opinion 20050101
Outcome studies in type 2 diabetes. Current medical research and opinion 20050101
Study of the liquid chromatography retention of some fibrate-type antihyperlipidemic drugs on C18 and CN columns: application for quantitation in pharmaceutical formulations. Journal of AOAC International 20050101
A two-dimensional electrophoresis preliminary approach to human hepatocarcinoma differentiation induced by PPAR-agonists. Journal of cellular and molecular medicine 20050101
[Dyslipidaemia and diabetes mellitus]. Revue medicale de Liege 20050101
Mechanisms of calcium release from the sarcoplasmic reticulum in skeletal muscle. Advances in experimental medicine and biology 20050101
The effect of ciprofibrate on flow-mediated dilation and inflammatory markers in patients with combined hyperlipidemia. Endothelium : journal of endothelial cell research 20050101
Enzymatic examination of potential interaction between statins or fibrates and consumed Tricholoma equestre. Przeglad lekarski 20050101
Macrodissection versus microdissection of rectal carcinoma: minor influence of stroma cells to tumor cell gene expression profiles. BMC genomics 20050101
Single and chronic administration of ciprofibrate or of ciprofibrate-glycinate in male Fischer 344 rats: comparison of the effects on morphological and biochemical parameters in liver and blood. European journal of drug metabolism and pharmacokinetics 20050101
Evaluation of the carcinogenic potential of clofibrate in the neonatal mouse. International journal of toxicology 20050101
Peroxisome proliferator-activated receptor-gamma and its agonists in hypertension and atherosclerosis : mechanisms and clinical implications. American journal of cardiovascular drugs : drugs, devices, and other interventions 20050101
Hypertriglyceridemia, the coronary heart disease risk marker 'solved'. Acta physiologica Hungarica 20050101
[Variability in primary care drug prescription in 2003 in Castile-la Mancha, Spain]. Revista espanola de salud publica 20050101
[Fibrate-induced increase in serum creatinine levels: two cases]. Therapie 20050101
Suitability of hollow fibre liquid-phase microextraction for the determination of acidic pharmaceuticals in wastewater by liquid chromatography-electrospray tandem mass spectrometry without matrix effects. Journal of chromatography. A 20041217
Acute and chronic effects of clofibrate and clofibric acid on the enzymes acetylcholinesterase, lactate dehydrogenase and catalase of the mosquitofish, Gambusia holbrooki. Chemosphere 20041201
Lipid lowering drugs prescription and the risk of peripheral neuropathy: an exploratory case-control study using automated databases. Journal of epidemiology and community health 20041201
Incidence of hospitalized rhabdomyolysis in patients treated with lipid-lowering drugs. JAMA 20041201
Induction of phytohormones and differential gene expression in citrus flowers infected by the fungus Colletotrichum acutatum. Molecular plant-microbe interactions : MPMI 20041201
Therapeutic approaches to raising plasma HDL-cholesterol levels. Nature clinical practice. Cardiovascular medicine 20041201
[Low HDL-cholesterol, high triglycerides--well known but often ignored]. Praxis 20041110
Lipid lowering effects of statins and fibrates in the management of HIV dyslipidemias associated with antiretroviral therapy in HIV clinical practice. The Journal of infection 20041101
Clofibric and ethacrynic acids prevent experimental pyelonephritis by Escherichia coli in mice. FEMS immunology and medical microbiology 20041101
Statin and fibrate treatment of combined hyperlipidemia: the effects on some novel risk factors. Thrombosis and haemostasis 20041101
Down regulation of hepatic PPARalpha function by AhR ligand. The Journal of veterinary medical science 20041101
Peroxisome proliferator-activated receptors as regulators of lipid metabolism; tissue differential expression in adipose tissues during cold acclimatization and hibernation of jerboa (Jaculus orientalis). Biochimie 20041101
Pharmaceuticals and personal care products (PPCPs) and endocrine disrupting chemicals (EDCs) in stormwater canals and Bayou St. John in New Orleans, Louisiana, USA. The Science of the total environment 20041015
Activation of peroxisome proliferator-activated receptor alpha in rat spinal cord after peripheral noxious stimulation. Neuroscience letters 20041007
The effect of statins and fibrates on interferon-gamma and interleukin-2 release in patients with primary type II dyslipidemia. Atherosclerosis 20041001
Raising high-density lipoprotein cholesterol with inhibitors of cholesteryl ester transfer protein - a new approach to coronary artery disease. Expert opinion on investigational drugs 20041001
Determination of some acidic drugs in surface and sewage treatment plant waters by capillary electrophoresis-electrospray ionization-mass spectrometry. Electrophoresis 20041001
Management of dyslipidaemia in HIV-infected patients receiving antiretroviral therapy. Antiviral therapy 20041001
Co-induction of methyltransferase Rv0560c by naphthoquinones and fibric acids suggests attenuation of isoprenoid quinone action in Mycobacterium tuberculosis. Canadian journal of microbiology 20041001
PPARalpha-dependent modulation of hepatic CYP1A by clofibric acid in rats. Archives of toxicology 20040901
Fibrates induce hepatic peroxisome and mitochondrial proliferation without overt evidence of cellular proliferation and oxidative stress in cynomolgus monkeys. Carcinogenesis 20040901
Therapeutic approaches in the prevention of cardiovascular disease in metabolic syndrome and in patients with type 2 diabetes. Current opinion in cardiology 20040901
Diabetes mellitus and unstable coronary artery disease: improved clinical outcome of coronary artery stenting in an era of glycoprotein IIb/IIIa inhibitors and lipid-lowering therapy. Coronary artery disease 20040901
Utility of currently available modes of therapy in reaching lipid goals. The Journal of the American Osteopathic Association 20040901
Coadministration of multidrug therapy to achieve lipid goals. The Journal of the American Osteopathic Association 20040901
Peroxisome proliferator-activated receptor (PPAR)-alpha: a pharmacological target with a promising future. Pharmaceutical research 20040901
PPARalpha agonists stimulate progastrin production in human colorectal carcinoma cells. Regulatory peptides 20040815
Effects of vitamin E on the NF-kappaB pathway in rats treated with the peroxisome proliferator, ciprofibrate. Toxicology and applied pharmacology 20040815
Analysis by liquid chromatography-electrospray ionization tandem mass spectrometry and acute toxicity evaluation for beta-blockers and lipid-regulating agents in wastewater samples. Journal of chromatography. A 20040813
Statins but not fibrates are associated with a reduced risk of venous thromboembolism: a hospital-based case-control study. Fundamental & clinical pharmacology 20040801
Protective behavior survey, West Nile virus, British Columbia. Emerging infectious diseases 20040801
Leaching behaviour of pharmaceuticals in soil-testing-systems: a part of an environmental risk assessment for groundwater protection. The Science of the total environment 20040726
PPARalpha agonists clofibrate and gemfibrozil inhibit cell growth, down-regulate hCG and up-regulate progesterone secretions in immortalized human trophoblast cells. Biochemical pharmacology 20040715
Effects of peroxisome proliferator-activated receptor alpha activation on pathways contributing to cholesterol homeostasis in rat hepatocytes. Biochimica et biophysica acta 20040705
Gastrointestinally distributed UDP-glucuronosyltransferase 1A10, which metabolizes estrogens and nonsteroidal anti-inflammatory drugs, depends upon phosphorylation. The Journal of biological chemistry 20040702
The peroxisome proliferator-activated receptor alpha (PPARalpha) agonist ciprofibrate inhibits apolipoprotein B mRNA editing in low density lipoprotein receptor-deficient mice: effects on plasma lipoproteins and the development of atherosclerotic lesions. The Journal of biological chemistry 20040702
Mitochondrial respiratory chain dysfunction, a non-receptor-mediated effect of synthetic PPAR-ligands: biochemical and pharmacological implications. Biochemical and biophysical research communications 20040702
Adiponectin in peritoneal dialysis patients: a comparison with hemodialysis patients and subjects with normal renal function. American journal of kidney diseases : the official journal of the National Kidney Foundation 20040601
Statin and fibrate associated myopathy: study of eight patients. Arquivos de neuro-psiquiatria 20040601
Sexually dimorphic metabolism of branched-chain lipids in C57BL/6J mice. Journal of lipid research 20040501
Environmental risk assessment of six human pharmaceuticals: are the current environmental risk assessment procedures sufficient for the protection of the aquatic environment? Environmental toxicology and chemistry 20040501
Highlights from the 74th Congress of the European Atherosclerosis Society. Timely topics in medicine. Cardiovascular diseases 20040501
Characterization of the species-specificity of peroxisome proliferators in rat and human hepatocytes. Toxicological sciences : an official journal of the Society of Toxicology 20040401
Regulation of apoptosis by peroxisome proliferators. Toxicology letters 20040401
Properties of an alginate gel bead containing a chitosan-drug salt. Biological & pharmaceutical bulletin 20040301
Liquid chromatography with triple-quadrupole or quadrupole-time of flight mass spectrometry for screening and confirmation of residues of pharmaceuticals in water. Analytical and bioanalytical chemistry 20040201
Evaluation of the dermal subchronic toxicity of phenoxyethyl isobutyrate in the rat. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20040201
Kinetic study of photocatalytic degradation of carbamazepine, clofibric acid, iomeprol and iopromide assisted by different TiO2 materials--determination of intermediates and reaction pathways. Water research 20040201
Two-step liquid-liquid-liquid microextraction of nonsteroidal antiinflammatory drugs in wastewater. Analytical chemistry 20040101
In vitro reactivity of carboxylic acid-CoA thioesters with glutathione. Chemical research in toxicology 20040101
Miniaturized fluorescent RNA dot blot method for rapid quantitation of gene expression. BMC biotechnology 20040101
Application of UV-derivative spectra for determination of four antihyperlipidaemic drugs in pharmaceutical formulations. Acta poloniae pharmaceutica 20040101
Role of fibric acid derivatives in the management of risk factors for coronary heart disease. Drugs 20040101
Transport of pharmaceutically active compounds in saturated laboratory columns. Ground water 20040101
Effects of advanced oxidation processes (AOPs) on the toxicity of a mixture of pharmaceuticals. Water science and technology : a journal of the International Association on Water Pollution Research 20040101
Toxic effect of pharmaceuticals on methanogenesis. Water science and technology : a journal of the International Association on Water Pollution Research 20040101
Comparative effects of lipid-lowering therapies. Progress in cardiovascular diseases 20040101
Overexpression of SR-BI by adenoviral vector reverses the fibrateinduced hypercholesterolemia of apolipoprotein E-deficient mice. The Journal of biological chemistry 20031226
Determination of acidic pharmaceuticals, antibiotics and ivermectin in river sediment using liquid chromatography-tandem mass spectrometry. Journal of chromatography. A 20031222
Cardiovascular disease with diabetes or the metabolic syndrome: should statins or fibrates be first line lipid therapy? Current opinion in lipidology 20031201
Liver gene expression profiles of rats treated with clofibric acid: comparison of whole liver and laser capture microdissected liver. The American journal of pathology 20031201
Occurrence of neutral and acidic drugs in the effluents of Canadian sewage treatment plants. Environmental toxicology and chemistry 20031201
Distribution of acidic and neutral drugs in surface waters near sewage treatment plants in the lower Great Lakes, Canada. Environmental toxicology and chemistry 20031201
p-Chlorophenoxyisobutyric acid impairs auxin response in Arabidopsis root. Plant physiology 20031101
Ozonation and H2O2/UV treatment of clofibric acid in water: a kinetic investigation. Journal of hazardous materials 20031031
Determination of selected human pharmaceutical compounds in effluent and surface water samples by high-performance liquid chromatography-electrospray tandem mass spectrometry. Journal of chromatography. A 20031010
Cell proliferation and apoptosis are altered in mice deficient in the NF-kappaB p50 subunit after treatment with the peroxisome proliferator ciprofibrate. Toxicological sciences : an official journal of the Society of Toxicology 20031001
Pharmaceutical and personal care products in sewage treatment works. Journal of environmental monitoring : JEM 20031001
Hypertriglyceridemia increases mitochondrial resting respiration and susceptibility to permeability transition. Journal of bioenergetics and biomembranes 20031001
Liver gene expression in rats in response to the peroxisome proliferator-activated receptor-alpha agonist ciprofibrate. Physiological genomics 20030929
Simultaneous determination of clofibrate and its active metabolite clofibric acid in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet absorbance detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030905
Fate of pharmaceuticals--photodegradation by simulated solar UV-light. Chemosphere 20030901
Effects of clofibric acid on mRNA expression profiles in primary cultures of rat, mouse and human hepatocytes. Toxicology and applied pharmacology 20030901
Ethylene promotes the induction by auxin of the cortical microtubule randomization required for low-pH-induced root hair initiation in lettuce (Lactuca sativa L.) seedlings. Plant & cell physiology 20030901
Influence of etofibrate on LDL-subtype distribution in patients with diabetic dyslipoproteinemia. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030901
The peroxisome-proliferator-activated receptor alpha agonist ciprofibrate severely aggravates hypercholesterolaemia and accelerates the development of atherosclerosis in mice lacking apolipoprotein E. The Biochemical journal 20030801
Chromatin sphingomyelin changes in cell proliferation and/or apoptosis induced by ciprofibrate. Journal of cellular physiology 20030801
Action of ciprofibrate in type IIb hyperlipoproteinemia: modulation of the atherogenic lipoprotein phenotype and stimulation of high-density lipoprotein-mediated cellular cholesterol efflux. The Journal of clinical endocrinology and metabolism 20030801
[Long-term hypolipidemic treatment of mixed hyperlipidemia with a combination of statins and fibrates]. Casopis lekaru ceskych 20030801
Reshaping the dyslipidemia management paradigm. Postgraduate medicine 20030801
CHD risk equivalents and the metabolic syndrome. Trial evidence supports aggressive management. Postgraduate medicine 20030801
Pharmaceuticals and personal care products (PPCPs) in surface and treated waters of Louisiana, USA and Ontario, Canada. The Science of the total environment 20030720
Ecotoxicological impact of pharmaceuticals found in treated wastewaters: study of carbamazepine, clofibric acid, and diclofenac. Ecotoxicology and environmental safety 20030701
Fibrates and renal function. Clinical nephrology 20030701
LDL-cholesterol, HDL-cholesterol or triglycerides--which is the culprit? Diabetes research and clinical practice 20030701
Short-term tests with a pilot sewage plant and biofilm reactors for the biological degradation of the pharmaceutical compounds clofibric acid, ibuprofen, and diclofenac. The Science of the total environment 20030620
Peroxisome proliferator-activated receptor ligands affect growth-related gene expression in human leukemic cells. The Journal of pharmacology and experimental therapeutics 20030601
Serum lipid comparison in patients treated by statins or fibrates: existence of bad HDL-C responders to statins. Acta cardiologica 20030601
[Ciprofibrate-induced acute cholestatic hepatitis]. Annales d'endocrinologie 20030601
UDP-glucuronosyltransferase-dependent bioactivation of clofibric acid to a DNA-damaging intermediate in mouse hepatocytes. Chemico-biological interactions 20030506
Identification of coenzyme A-related tolmetin metabolites in rats: relationship with reactive drug metabolites. Xenobiotica; the fate of foreign compounds in biological systems 20030501
Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen. Carcinogenesis 20030501
Regulation by carbohydrate and clofibric acid of palmitoyl-CoA chain elongation in the liver of rats. Lipids 20030501
Determination of polar pharmaceuticals in sewage water of Greece by gas chromatography-mass spectrometry. Chemosphere 20030401
Occurrence and fate of carbamazepine, clofibric acid, diclofenac, ibuprofen, ketoprofen, and naproxen in surface waters. Environmental science & technology 20030315
Pharmaceuticals in STP effluents and their solar photodegradation in aquatic environment. Chemosphere 20030301
Cell-specific toxicity of fibrates in human embryonal rhabdomyosarcoma cells. Naunyn-Schmiedeberg's archives of pharmacology 20030301
Fibrates and medroxyprogesterone acetate induce apoptosis of primary Burkitt's lymphoma cells and cell lines: potential for applying old drugs to a new disease. Leukemia 20030301
Antral G cells in rats during dosing with a PPAR alpha agonist: a morphometric and immunocytochemical study. Medical electron microscopy : official journal of the Clinical Electron Microscopy Society of Japan 20030301
What future for combination therapies? International journal of clinical practice. Supplement 20030301
Peroxisome proliferator-activated receptor alpha (PPARalpha)-mediated regulation of multidrug resistance 2 (Mdr2) expression and function in mice. The Biochemical journal 20030201
Peroxisome proliferator ameliorates endothelial dysfunction in a murine model of hyperhomocysteinemia. American journal of physiology. Lung cellular and molecular physiology 20030201
Fibrates and C-reactive protein. Clinica chimica acta; international journal of clinical chemistry 20030201
Inhibition of TNF-alpha-induced RANTES expression in human hepatocyte-derived cells by fibrates, the hypolipidemic drugs. International immunopharmacology 20030201
Fibrates down-regulate IL-1-stimulated C-reactive protein gene expression in hepatocytes by reducing nuclear p50-NFkappa B-C/EBP-beta complex formation. Blood 20030115
Induction of hepatic ABC transporter expression is part of the PPARalpha-mediated fasting response in the mouse. Gastroenterology 20030101
Different effects of the liver mitogens triiodo-thyronine and ciprofibrate on the development of rat hepatocellular carcinoma. Toxicologic pathology 20030101
[Conjugation reactions of ciprofibrate with human and laboratory animals]. Arzneimittel-Forschung 20030101
Evidence of cytochrome P450-catalyzed cleavage of the ether bond of phenoxybutyrate herbicides in Rhodococcus erythropolis K2-3. Biodegradation 20030101
A comprehensive description of muscle symptoms associated with lipid-lowering drugs. Cardiovascular drugs and therapy 20030101
Clofibric acid stimulates branched-chain amino acid catabolism by three mechanisms. Archives of biochemistry and biophysics 20021115
Effects of various fibrates on serum alkaline phosphatase activity. Atherosclerosis 20021101
In vivo and in vitro induction of cytochrome P450 enzymes in beagle dogs. Drug metabolism and disposition: the biological fate of chemicals 20021101
Dysbetalipoproteinaemia--clinical and pathophysiological features. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20021101
Peroxisome proliferators compete and ameliorate Hcy-mediated endocardial endothelial cell activation. American journal of physiology. Cell physiology 20021001
Effect of ciprofibrate on lipoproteins, fibrinogen, renal function, and hepatic enzymes. Journal of cardiovascular pharmacology and therapeutics 20021001
PPAR alpha stimulates the rat gastrin-producing cell. Molecular and cellular endocrinology 20020930
Differentiated properties of hepatocytes induced from pancreatic cells. Hepatology (Baltimore, Md.) 20020901
Removal of pharmaceuticals during drinking water treatment. Environmental science & technology 20020901
Current drug treatments for lipid management. Managed care (Langhorne, Pa.) 20020901
Drugs and personal care products as ubiquitous pollutants: occurrence and distribution of clofibric acid, caffeine and DEET in the North Sea. The Science of the total environment 20020805
HMG-CoA reductase inhibition and PPAR- alpha activation both inhibit cyclosporin A induced endothelin-1 secretion in cultured endothelial cells. Clinical science (London, England : 1979) 20020801
Ciglitazone inhibits plasmin-induced proinflammatory monocyte activation via modulation of p38 MAP kinase activity. Thrombosis and haemostasis 20020801
Fibrates suppress chenodeoxycholic acid-induced RANTES expression through inhibition of NF-kappaB activation. European journal of pharmacology 20020712
Peroxisome proliferator-activated receptor agonists, hyperlipidaemia, and atherosclerosis. Pharmacology & therapeutics 20020701
Detection of pharmaceutical contaminations of river, pond, and tap water from Cologne (Germany) and surroundings. International journal of hygiene and environmental health 20020701
Molecular modelling of the peroxisome proliferator-activated receptor alpha (PPAR alpha) from human, rat and mouse, based on homology with the human PPAR gamma crystal structure. Toxicology in vitro : an international journal published in association with BIBRA 20020601
PPARalpha suppresses insulin secretion and induces UCP2 in insulinoma cells. Journal of lipid research 20020601
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Analysis of acidic drugs in the effluents of sewage treatment plants using liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of chromatography. A 20020405
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Simultaneous quantification of neutral and acidic pharmaceuticals and pesticides at the low-ng/l level in surface and waste water. Journal of chromatography. A 20010316
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Pharmacological characterization of chloride channels belonging to the ClC family by the use of chiral clofibric acid derivatives. Molecular pharmacology 20000901
Detection of chemical-induced differential expression of rat hepatic cytochrome P450 mRNA transcripts using branched DNA signal amplification technology. Drug metabolism and disposition: the biological fate of chemicals 20000501
Differential induction of hepatic drug-metabolizing enzymes by fenvaleric acid in male rats. Toxicological sciences : an official journal of the Society of Toxicology 19991201
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Fibrates suppress fibrinogen gene expression in rodents via activation of the peroxisome proliferator-activated receptor-alpha. Blood 19990501
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Mechanisms of peroxisome proliferation by perfluorooctanoic acid and endogenous fatty acids. General pharmacology 19980801
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[Rhabdomyolysis and unexplained malaise. Role of combination of ciprofibrate and norfloxacin]. La Revue de medecine interne 19960101
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The effects of diquat and ciprofibrate on mRNA expression and catalytic activities of hepatic xenobiotic metabolizing and antioxidant enzymes in rat liver. Toxicology and applied pharmacology 19950901
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The herbicide dicamba (2-methoxy-3,6-dichlorobenzoic acid) is a peroxisome proliferator in rats. Fundamental and applied toxicology : official journal of the Society of Toxicology 19950601
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The effects of clofibrate and bezafibrate on cholesterol metabolism in the liver of the male rat. Lipids 19941101
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A recombinant phenobarbital-inducible rat liver UDP-glucuronosyltransferase (UDP-glucuronosyltransferase 2B1) stably expressed in V79 cells catalyzes the glucuronidation of morphine, phenols, and carboxylic acids. Molecular pharmacology 19940101
Further studies on the involvement of selenium in peroxisome proliferation in rat liver. Comparison of effects with clofibric acid and perfluorooctanoic acid and the pharmacokinetics of [14C]clofibrate. Biochemical pharmacology 19931117
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Lack of peroxisomal enzyme inducibility in rat hepatic preneoplastic lesions induced by mutagenic carcinogens: contrasted expression of glutathione S-transferase P form and enoyl CoA hydratase. Carcinogenesis 19930301
Complementary deoxyribonucleic acid cloning and expression of a human liver uridine diphosphate-glucuronosyltransferase glucuronidating carboxylic acid-containing drugs. The Journal of pharmacology and experimental therapeutics 19930101
Analysis of activated protooncogenes in B6C3F1 mouse liver tumors induced by ciprofibrate, a potent peroxisome proliferator. Carcinogenesis 19930101
Mechanism of action of fibrates. Postgraduate medical journal 19930101
Convergence of 9-cis retinoic acid and peroxisome proliferator signalling pathways through heterodimer formation of their receptors. Nature 19920827
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Plasma levels of HGF in rats treated with tumor promoters. Carcinogenesis 19920101
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On the mechanism of the hepatocarcinogenicity of peroxisome proliferators. Chemico-biological interactions 19910101
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Characterization of the hepatic responses to the short-term administration of ciprofibrate in several rat strain. Co-induction of microsomal cytochrome P-450 IVA1 and peroxisome proliferation. Biochemical pharmacology 19900901
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Lack of expression of glutathione-S-transferase P, gamma-glutamyl transpeptidase, and alpha-fetoprotein messenger RNAs in liver tumors induced by peroxisome proliferators. Cancer research 19880901
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Absence of gamma-glutamyltranspeptidase activity in lung metastasis in rats with hepatocellular carcinomas induced by ciprofibrate, a peroxisome proliferator. Cancer letters 19871201
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