1-Methylpiperazine
| Title | Journal |
|---|---|
| Disposition and metabolism of 14C-dovitinib (TKI258), an inhibitor of FGFR and VEGFR, after oral administration in patients with advanced solid tumors. | Cancer chemotherapy and pharmacology 20121101 |
| Toward rational design of amine solutions for PCC applications: the kinetics of the reaction of CO2(aq) with cyclic and secondary amines in aqueous solution. | Environmental science & technology 20120703 |
| Simultaneous determination of four plant hormones in bananas by molecularly imprinted solid-phase extraction coupled with high performance liquid chromatography. | The Analyst 20120621 |
| 5-Methyl-3,3-bis-(4-methyl-piperazin-1-yl)-1-[2-(4-methyl-piperazin-1-yl)eth-yl]indolin-2-one. | Acta crystallographica. Section E, Structure reports online 20120601 |
| 12-{[4-(2-Fluoro-phen-yl)piperazin-1-yl]-meth-yl}-9α-hy-droxy-4,8-dimethyl-3,14-dioxatricyclo-[9.3.0.0]tetra-dec-7-en-13-one. | Acta crystallographica. Section E, Structure reports online 20120301 |
| Novel benzothiazole, benzimidazole and benzoxazole derivatives as potential antitumor agents: synthesis and preliminary in vitro biological evaluation. | Molecules (Basel, Switzerland) 20120117 |
| Discovery of a novel class of orally active trypanocidal N-myristoyltransferase inhibitors. | Journal of medicinal chemistry 20120112 |
| Divalent-metal-stabilized aluminophosphates exhibiting a new zeolite framework topology. | Inorganic chemistry 20120102 |
| New N-methylpiperazinyl derivatives of bicyclic antiprotozoal compounds. | European journal of medicinal chemistry 20120101 |
| 2-(5-Fluoro-2,3-dioxoindolin-1-yl)ethyl 4-methyl-piperazine-1-carbodithio-ate. | Acta crystallographica. Section E, Structure reports online 20120101 |
| Structure and electronic properties of Alq3 derivatives with electron acceptor/donor groups at the C4 positions of the quinolate ligands: a theoretical study. | Journal of molecular modeling 20111201 |
| (2R)-4-[(9H-Fluoren-9-ylmeth-oxy)carbon-yl]-2-methyl-piperazin-1-ium chloride. | Acta crystallographica. Section E, Structure reports online 20111201 |
| Polymorphic form IV of olanzapine. | Acta crystallographica. Section C, Crystal structure communications 20111101 |
| 1-Methyl-piperazine-1,4-diium tetra-chloridozincate hemihydrate. | Acta crystallographica. Section E, Structure reports online 20111101 |
| 4-(4-Methyl-piperazin-1-yl)-3-(5-phenyl-1,3,4-oxadiazol-2-yl)-7-(trifluoro-meth-yl)quinoline. | Acta crystallographica. Section E, Structure reports online 20111101 |
| Influence of pharmacogenetic variability on the pharmacokinetics and toxicity of the aurora kinase inhibitor danusertib. | Investigational new drugs 20111001 |
| Determination of ofloxacin and lomefloxacin in chicken muscle using molecularly imprinted solid-phase extraction coupled with liquid chromatography. | Journal of separation science 20111001 |
| N-(4-Chloro-phen-yl)-4-methyl-piperazine-1-carboxamide. | Acta crystallographica. Section E, Structure reports online 20110901 |
| Bis(1-methyl-piperazine-1,4-diium) tetra-bromidocuprate(II). | Acta crystallographica. Section E, Structure reports online 20110701 |
| Bis(1-methyl-piperazine-1,4-diium) tetra-chloridocuprate(II). | Acta crystallographica. Section E, Structure reports online 20110701 |
| Non-peptide NK1 receptor ligands based on the 4-phenylpyridine moiety. | Bioorganic & medicinal chemistry 20110401 |
| 5-Nitroimidazole-based 1,3,4-thiadiazoles: heterocyclic analogs of metronidazole as anti-Helicobacter pylori agents. | Archiv der Pharmazie 20110301 |
| Synthesis of 1H-pyrazole-1-carboxamide derivatives and their antiproliferative activity against melanoma cell line. | Archiv der Pharmazie 20110301 |
| 1-[4-(3-{[5-(4-Chloro-phen-yl)furan-2-yl]methyl-idene-amino}-2,5-dioxoimidazol-idin-1-yl)but-yl]-4-methyl-piperazine-1,4-diium dichloride hemihydrate. | Acta crystallographica. Section E, Structure reports online 20110201 |
| Critical appraisal of nilotinib in frontline treatment of chronic myeloid leukemia. | Cancer management and research 20110101 |
| Studies on the anthelmintic property of aminobenzylated mannich bases. | Journal of young pharmacists : JYP 20110101 |
| Combined pharmacophore modeling, docking, and 3D-QSAR studies of PLK1 inhibitors. | International journal of molecular sciences 20110101 |
| 3D QSAR pharmacophore modeling, in silico screening, and density functional theory (DFT) approaches for identification of human chymase inhibitors. | International journal of molecular sciences 20110101 |
| Tetrasubstituted naphthalene diimide ligands with selectivity for telomeric G-quadruplexes and cancer cells. | Bioorganic & medicinal chemistry letters 20101115 |
| Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds. | Bioorganic & medicinal chemistry 20100915 |
| Peptidyl alpha-ketoamides with nucleobases, methylpiperazine, and dimethylaminoalkyl substituents as calpain inhibitors. | Journal of medicinal chemistry 20100909 |
| In vitro and in vivo studies of the trypanocidal properties of WRR-483 against Trypanosoma cruzi. | PLoS neglected tropical diseases 20100901 |
| catena-Poly[(S)-2-methyl-piperazine-1,4-diium [[trichloridobismuthate(III)]-di-μ-chlorido]]. | Acta crystallographica. Section E, Structure reports online 20100901 |
| Chalcogenides of the aminomethylphosphines derived from 1-methylpiperazine, 1-ethylpiperazine and morpholine: NMR, DFT and structural studies for determination of electronic and steric properties of the phosphines. | Dalton transactions (Cambridge, England : 2003) 20100828 |
| Determination of individual proton affinities of ofloxacin from its UV-Vis absorption, fluorescence and charge-transfer spectra: effect of inclusion in beta-cyclodextrin on the proton affinities. | The journal of physical chemistry. B 20100805 |
| Crystal Structures of TbCatB and rhodesain, potential chemotherapeutic targets and major cysteine proteases of Trypanosoma brucei. | PLoS neglected tropical diseases 20100601 |
| Streamlined, automated protocols for the production of milligram quantities of untagged recombinant human cyclophilin-A (hCypA) and untagged human proliferating cell nuclear antigen (hPCNA) using AKTAxpress. | Protein expression and purification 20100501 |
| A statistics-based platform for quantitative N-terminome analysis and identification of protease cleavage products. | Molecular & cellular proteomics : MCP 20100501 |
| Synthesis and antimicrobial activities of some new 1,2,3-triazole derivatives. | Molecules (Basel, Switzerland) 20100408 |
| Conjugate addition of nucleophiles to the vinyl function of 2-chloro-4-vinylpyrimidine derivatives. | Molecules (Basel, Switzerland) 20100319 |
| Detection of nitric oxide in tissue samples by ESI-MS. | The Analyst 20100201 |
| Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. | Chemical & pharmaceutical bulletin 20100201 |
| Imatinibium dipicrate. | Acta crystallographica. Section E, Structure reports online 20100201 |
| Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors. | Journal of medicinal chemistry 20100128 |
| Theoretical and experimental studies of the isomeric protonation in solution for a prototype aliphatic ring containing two nitrogens. | The journal of physical chemistry. B 20100114 |
| Novel imatinib derivatives with altered specificity between Bcr-Abl and FMS, KIT, and PDGF receptors. | ChemMedChem 20100101 |
| [Synthesis, modifications, and antimicrobial activity of the methylpiperazinyl amides of triterpenic acids]. | Bioorganicheskaia khimiia 20100101 |
| [Synthesis and pharmacological activity of amides and ozonolysis product of maleopimaric acid]. | Bioorganicheskaia khimiia 20100101 |
| Solution structure of a covalently bound pyrrolo[2,1-c][1,4]benzodiazepine-benzimidazole hybrid to a 10mer DNA duplex. | Biochemistry 20091229 |
| [2-(4-Methyl-piperazin-1-ylmeth-yl)phen-yl]diphenyl-phosphane. | Acta crystallographica. Section E, Structure reports online 20091201 |
| Regioselective reaction: synthesis and pharmacological study of Mannich bases containing ibuprofen moiety. | European journal of medicinal chemistry 20090901 |
| Synthesis of some new 1,3,4-thiadiazol-2-ylmethyl-1,2,4-triazole derivatives and investigation of their antimicrobial activities. | European journal of medicinal chemistry 20090701 |
| Discovery of substituted N'-(2-oxoindolin-3-ylidene)benzohydrazides as new apoptosis inducers using a cell- and caspase-based HTS assay. | Bioorganic & medicinal chemistry letters 20090515 |
| Manipulation of fluorescent and colorimetric changes of fluorescein derivatives and applications for sensing silver ions. | Chemical communications (Cambridge, England) 20090314 |
| Synthesis of some new 1,2,4-triazoles, their Mannich and Schiff bases and evaluation of their antimicrobial activities. | European journal of medicinal chemistry 20090301 |
| Synthesis and spectral characterization of a new class of N-(N-methylpiperazinoacetyl)-2,6-diarylpiperidin-4-ones: antimicrobial, analgesic and antipyretic studies. | European journal of medicinal chemistry 20090201 |
| Structure elucidation of thioketone analogues of sildenafil detected as adulterants in herbal aphrodisiacs. | Journal of pharmaceutical and biomedical analysis 20090115 |
| Hoechst 33342: the dye that enabled differentiation of living X-and Y-chromosome bearing mammalian sperm. | Theriogenology 20090101 |
| The structure of the leukemia drug imatinib bound to human quinone reductase 2 (NQO2). | BMC structural biology 20090101 |
| The steroid and xenobiotic receptor (SXR), beyond xenobiotic metabolism. | Nuclear receptor signaling 20090101 |
| Masitinib (AB1010), a potent and selective tyrosine kinase inhibitor targeting KIT. | PloS one 20090101 |
| Nilotinib: optimal therapy for patients with chronic myeloid leukemia and resistance or intolerance to imatinib. | Drug design, development and therapy 20090101 |
| Proteomics: challenges, techniques and possibilities to overcome biological sample complexity. | Human genomics and proteomics : HGP 20090101 |
| Structure-activity studies on a series of a 2-aminopyrimidine-containing histamine H4 receptor ligands. | Journal of medicinal chemistry 20081023 |
| Copper(I) cyanide networks: synthesis, structure, and luminescence behavior. Part 2. Piperazine ligands and hexamethylenetetramine. | Inorganic chemistry 20080804 |
| Use of N-methylpiperazine for the preparation of piperazine-based unsymmetrical bis-ureas as anti-HIV agents. | ChemMedChem 20080701 |
| Gene expression signatures and small-molecule compounds link a protein kinase to Plasmodium falciparum motility. | Nature chemical biology 20080601 |
| 3-(4-Methyl-piperazin-1-yl)isobenzofuran-1(3H)-one. | Acta crystallographica. Section E, Structure reports online 20080501 |
| Morpholine-based immonium and halogenoamidinium salts as coupling reagents in Peptide synthesis1. | The Journal of organic chemistry 20080404 |
| Determination of analogs of sildenafil and vardenafil in foods by column liquid chromatography with a photodiode array detector, mass spectrometry, and nuclear magnetic resonance spectrometry. | Journal of AOAC International 20080101 |
| Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation. | Proteome science 20080101 |
| Crystal structures of the FAK kinase in complex with TAE226 and related bis-anilino pyrimidine inhibitors reveal a helical DFG conformation. | PloS one 20080101 |
| Development and targeted use of nilotinib in chronic myeloid leukemia. | Drug design, development and therapy 20080101 |
| Synthesis and Pharmacological Evaluation of (6-Substituted 4-Oxo-4H-chromene-3 yl) methyl N-substituted Aminoacetates. | Indian journal of pharmaceutical sciences 20080101 |
| Refining targeted therapies in chronic myeloid leukemia: development and application of nilotinib, a step beyond imatinib. | OncoTargets and therapy 20080101 |
| N-Methyl-piperazinediium penta-chloridoanti-monate(III) monohydrate. | Acta crystallographica. Section E, Structure reports online 20080101 |
| Use of liquid chromatography-mass spectrometry and a chemical cleavage reaction for the structure elucidation of a new sildenafil analogue detected as an adulterant in an herbal dietary supplement. | Journal of pharmaceutical and biomedical analysis 20070815 |
| Synthesis of o-sulfamidotriazobenzenes from 1,1'-sulfonylbis(benzotriazole). | The Journal of organic chemistry 20070720 |
| DFT and ab initio calculations of the vibrational frequencies and visible spectra of triazenes derived from cyclic amines. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20070601 |
| Quinazolinone fungal efflux pump inhibitors. Part 3: (N-methyl)piperazine variants and pharmacokinetic optimization. | Bioorganic & medicinal chemistry letters 20070515 |
| Structure elucidation of a novel analogue of sildenafil detected as an adulterant in an herbal dietary supplement. | Journal of pharmaceutical and biomedical analysis 20070411 |
| Structure determination of new analogues of vardenafil and sildenafil in dietary supplements. | Food additives and contaminants 20070201 |
| Array-based split-pool combinatorial screening of potential catalysts. | Journal of combinatorial chemistry 20070101 |
| Precise protein quantification based on peptide quantification using iTRAQ. | BMC bioinformatics 20070101 |
| NS-187 (INNO-406), a Bcr-Abl/Lyn dual tyrosine kinase inhibitor. | Analytical chemistry insights 20070101 |
| Synthesis and antitumor activity of CBI-bearing ester and carbamate prodrugs of CC-1065 analogue. | Bioorganic & medicinal chemistry 20061201 |
| Acenaphtho[1,2-b]pyrrole derivatives as new family of intercalators: various DNA binding geometry and interesting antitumor capacity. | Bioorganic & medicinal chemistry 20061015 |
| 7-(aryl/heteroaryl-2-ylethynyl)-4-phenylamino-3-quinolinecarbonitriles as new Src kinase inhibitors: addition of water solubilizing groups. | Bioorganic & medicinal chemistry letters 20060801 |
| Photoaddition of N-substituted piperazines to C60: an efficient approach to the synthesis of water-soluble fullerene derivatives. | Chemistry (Weinheim an der Bergstrasse, Germany) 20060717 |
| Phenothiazine molecule provides the basic chemical structure for various classes of pharmacotherapeutic agents. | American journal of therapeutics 20060101 |
| Synthesis and characterization of water-soluble phenylene-vinylene-based singlet oxygen sensitizers for two-photon excitation. | The Journal of organic chemistry 20050902 |
| Structural disorder in the complex of human pregnane X receptor and the macrolide antibiotic rifampicin. | Molecular endocrinology (Baltimore, Md.) 20050501 |
| Analysis of cell membrane aminophospholipids as isotope-tagged derivatives. | Journal of lipid research 20050501 |
| Identification of a 5-HT4 receptor antagonist clinical candidate through side-chain modification. | Bioorganic & medicinal chemistry letters 20050315 |
| Identification of 4-methylspinaceamine--a Pictet-Spengler condensation reaction product of histamine with acetaldehyde--in human urine. | Life sciences 20050128 |
| N-Chloroacyl-6-O-triphenylmethylchitosans: useful intermediates for synthetic modifications of chitosan. | Biomacromolecules 20050101 |
| Structure determination of a sildenafil analogue contained in commercial herb drinks. | Magnetic resonance in chemistry : MRC 20041201 |
| 1-Methylpiperazine-1,4-diium 4-nitrophthalate(2-) 4-nitrophthalic acid monohydrate. | Acta crystallographica. Section C, Crystal structure communications 20040901 |
| Solid-phase synthesis and evaluation of libraries of substituted 4,5-dihydropyridazinones as vasodilator agents. | The Journal of pharmacy and pharmacology 20040801 |
| Structure elucidation of sildenafil analogues in herbal products. | Food additives and contaminants 20040801 |
| DNA binding to guide the development of tetrahydroindeno[1,2-b]pyrido[4,3,2-de]quinoline derivatives as cytotoxic agents. | Journal of medicinal chemistry 20040701 |
| Isoelectric point separation of proteins by capillary pH-gradient ion-exchange chromatography. | Journal of chromatography. A 20040206 |
| DNA-directed alkylating agents: synthesis, antitumor activity and DNA affinity of bis-N,N'-trisubstituted 1,2,4-triazolo-piperazines. | Farmaco (Societa chimica italiana : 1989) 20040101 |
| [New derivatives of triazino- and imidazoindole with hepatoprotective activity]. | Biomeditsinskaia khimiia 20040101 |
| Physicochemical determinants for drug induced blockade of HERG potassium channels: effect of charge and charge shielding. | Current medicinal chemistry. Cardiovascular and hematological agents 20031001 |
| Solid-phase parallel synthesis of 17alpha-substituted estradiol sulfamate and phenol libraries using the multidetachable sulfamate linker. | Journal of combinatorial chemistry 20030101 |
| Mechanistic insights into the Pd(BINAP)-catalyzed amination of aryl bromides: kinetic studies under synthetically relevant conditions. | Journal of the American Chemical Society 20021127 |
| New pyridobenzodiazepine derivatives: modifications of the basic side chain differentially modulate binding to dopamine (D(4.2), D(2L)) and serotonin (5-HT(2A)) receptors. | Journal of medicinal chemistry 20021107 |
| 2,4-Disubstituted pyrroles: synthesis, traceless linking and pharmacological investigations leading to the dopamine D4 receptor partial agonist FAUC 356. | Bioorganic & medicinal chemistry letters 20020805 |
| NMR characterization of the DNA binding properties of a novel Hoechst 33258 analogue peptide building block. | Bioconjugate chemistry 20020101 |
| The interaction of 2-phenylbenzimidazole compounds with DNA: the influence of terminal substituents. | Nucleic acids research. Supplement (2001) 20020101 |
| Optimization of 4-phenylamino-3-quinolinecarbonitriles as potent inhibitors of Src kinase activity. | Journal of medicinal chemistry 20011108 |
| Tris-benzimidazole derivatives: design, synthesis and DNA sequence recognition. | Bioorganic & medicinal chemistry 20011101 |
| Tertiary N-glucuronides of clozapine and its metabolite desmethylclozapine in patient urine. | Drug metabolism and disposition: the biological fate of chemicals 20011001 |
| Ofloxacin/beta-cyclodextrin complexation. | Drug development and industrial pharmacy 20010701 |