1-Methyl-D-tryptophan
| Title | Journal |
|---|---|
| IDO2 is critical for IDO1-mediated T-cell regulation and exerts a non-redundant function in inflammation. | International immunology 20140701 |
| Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease. | Amino acids 20131201 |
| Addition of an indoleamine 2,3,-dioxygenase inhibitor to B cell-depletion therapy blocks autoreactive B cell activation and recurrence of arthritis in K/BxN mice. | Arthritis and rheumatism 20120701 |
| Effects of indoleamine 2,3-dioxygenases in carbon tetrachloride-induced hepatitis model of rats. | Cell biochemistry and function 20120601 |
| Suppression of azoxymethane-induced colonic preneoplastic lesions in rats by 1-methyltryptophan, an inhibitor of indoleamine 2,3-dioxygenase. | Cancer science 20120501 |
| The role of indoleamine 2, 3 dioxygenase in regulating host immunity to leishmania infection. | Journal of biomedical science 20120101 |
| Modulation of tumor tolerance in primary central nervous system malignancies. | Clinical & developmental immunology 20120101 |
| Targeting multiple-myeloma-induced immune dysfunction to improve immunotherapy outcomes. | Clinical & developmental immunology 20120101 |
| Altered tryptophan metabolism as a paradigm for good and bad aspects of immune privilege in chronic inflammatory diseases. | Frontiers in immunology 20120101 |
| Purification and kinetic characterization of human indoleamine 2,3-dioxygenases 1 and 2 (IDO1 and IDO2) and discovery of selective IDO1 inhibitors. | Biochimica et biophysica acta 20111201 |
| Novel action of 3,4-DAA ameliorating acute liver allograft injury. | Cell biochemistry and function 20111201 |
| Imatinib potentiates antitumor T cell responses in gastrointestinal stromal tumor through the inhibition of Ido. | Nature medicine 20110901 |
| The role of indoleamine 2, 3-dioxygenase in lepromatous leprosy immunosuppression. | Clinical and experimental immunology 20110801 |
| Contribution of dehydroepiandrosterone sulfate and progesterone to in vitro regulation of tolerogenic activity of IFN-α-induced dendritic cells. | Bulletin of experimental biology and medicine 20110601 |
| Vascular expression, activity and function of indoleamine 2,3-dioxygenase-1 following cerebral ischaemia-reperfusion in mice. | Naunyn-Schmiedeberg's archives of pharmacology 20110501 |
| Expression of indoleamine 2,3-dioxygenase in acute myeloid leukemia and the effect of its inhibition on cultured leukemia blast cells. | Medical oncology (Northwood, London, England) 20110301 |
| Interferon-γ regulates the proliferation and differentiation of mesenchymal stem cells via activation of indoleamine 2,3 dioxygenase (IDO). | PloS one 20110101 |
| The indoleamine-2,3-dioxygenase (IDO) inhibitor 1-methyl-D-tryptophan upregulates IDO1 in human cancer cells. | PloS one 20110101 |
| Vascular endothelial expression of indoleamine 2,3-dioxygenase 1 forms a positive gradient towards the feto-maternal interface. | PloS one 20110101 |
| Suppression of humoral immune response to hepatitis B surface antigen vaccine in BALB/c mice by 1-methyl-tryptophan co-administration. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101 |
| Indoleamine 2,3-dioxygenase-expressing leukemic dendritic cells impair a leukemia-specific immune response by inducing potent T regulatory cells. | Haematologica 20101201 |
| Mesenchymal stem cells inhibit complement activation by secreting factor H. | Stem cells and development 20101101 |
| Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model. | Journal of immunology (Baltimore, Md. : 1950) 20101015 |
| Inhibitor of indoleamine-2,3-dioxygenase 1-methyl-D-tryptophan can stimulate the growth of immunogenic tumors. | Bulletin of experimental biology and medicine 20101001 |
| Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2. | Amino acids 20100701 |
| A combination of the metabolic enzyme inhibitor APO866 and the immune adjuvant L-1-methyl tryptophan induces additive antitumor activity. | Experimental biology and medicine (Maywood, N.J.) 20100701 |
| Rational design of indoleamine 2,3-dioxygenase inhibitors. | Journal of medicinal chemistry 20100211 |
| The role of indoleamine 2,3-dioxygenase in retinal pigment epithelial cell-mediated immune modulation. | Ocular immunology and inflammation 20100101 |
| Melanoma: a model for testing new agents in combination therapies. | Journal of translational medicine 20100101 |
| Divergent modulation of Chlamydia pneumoniae infection cycle in human monocytic and endothelial cells by iron, tryptophan availability and interferon gamma. | Immunobiology 20100101 |
| Psychological stress-induced, IDO1-dependent tryptophan catabolism: implications on immunosuppression in mice and humans. | PloS one 20100101 |
| Role of the immunosuppressive enzyme indoleamine 2,3-dioxygenase in the progression of ovarian carcinoma. | Gynecologic oncology 20091101 |
| IDO and outcomes in ovarian cancer. | Gynecologic oncology 20091101 |
| Efficacy of levo-1-methyl tryptophan and dextro-1-methyl tryptophan in reversing indoleamine-2,3-dioxygenase-mediated arrest of T-cell proliferation in human epithelial ovarian cancer. | Cancer research 20090701 |
| Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. | Molecular psychiatry 20090501 |
| Allostimulatory activity of bone marrow-derived plasmacytoid dendritic cells is independent of indoleamine dioxygenase but regulated by inducible costimulator ligand expression. | Human immunology 20090501 |
| Combined effect of antiretroviral therapy and blockade of IDO in SIV-infected rhesus macaques. | Journal of immunology (Baltimore, Md. : 1950) 20090401 |
| Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway. | The international journal of biochemistry & cell biology 20090301 |
| Expression of indoleamine 2,3-dioxygenase in nasopharyngeal carcinoma impairs the cytolytic function of peripheral blood lymphocytes. | BMC cancer 20090101 |
| Overexpression of indoleamine 2,3-dioxygenase in human endometrial carcinoma cells induces rapid tumor growth in a mouse xenograft model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20081115 |
| The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation. | Journal of immunology (Baltimore, Md. : 1950) 20081015 |
| Interaction of tryptophan derivatives with SLC6A14 (ATB0,+) reveals the potential of the transporter as a drug target for cancer chemotherapy. | The Biochemical journal 20080915 |
| Indoleamine 2,3-dioxygenase expression promotes renal ischemia-reperfusion injury. | American journal of physiology. Renal physiology 20080701 |
| Antimicrobial and immunoregulatory effects mediated by human lung cells: role of IFN-gamma-induced tryptophan degradation. | FEMS immunology and medical microbiology 20080301 |
| Levo- but not dextro-1-methyl tryptophan abrogates the IDO activity of human dendritic cells. | Blood 20080215 |
| Increased striatal serotonin synthesis following cortical resection in children with intractable epilepsy. | Epilepsy research 20080201 |
| Toxicology and pharmacokinetics of 1-methyl-d-tryptophan: absence of toxicity due to saturating absorption. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080101 |
| Abatacept modulates human dendritic cell-stimulated T-cell proliferation and effector function independent of IDO induction. | Clinical immunology (Orlando, Fla.) 20080101 |
| HIV-induced type I interferon and tryptophan catabolism drive T cell dysfunction despite phenotypic activation. | PloS one 20080101 |
| Effect of Kidney-replenishing herb on the indoleamine 2,3-dioxygenase of human syncytiotrophoblasts cultured in vitro and the balance of helper T-cell cytokines. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20071101 |
| Nitric oxide and indoleamine 2,3-dioxygenase mediate CTLA4Ig-induced survival in heart allografts in rats. | Transplantation 20071027 |
| Proapoptotic activity of indoleamine 2,3-dioxygenase expressed in renal tubular epithelial cells. | American journal of physiology. Renal physiology 20070901 |
| Novel tryptophan catabolic enzyme IDO2 is the preferred biochemical target of the antitumor indoleamine 2,3-dioxygenase inhibitory compound D-1-methyl-tryptophan. | Cancer research 20070801 |
| Indoleamine 2, 3-dioxygenase expression in cells of human acute monocyte leukemia (M(5)) and acute lymphocyte leukemia and therapeutic effect of its inhibitor 1-methyl tryptophan. | Zhongguo shi yan xue ye xue za zhi 20070601 |
| Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. | Journal of immunology (Baltimore, Md. : 1950) 20061201 |
| Indoleamine 2,3-dioxygenase participates in the interferon-gamma-induced cell death process in cultured bovine luteal cells. | Biology of reproduction 20060301 |
| Inhibition of indoleamine 2,3-dioxygenase (IDO) enhances elimination of virus-infected macrophages in an animal model of HIV-1 encephalitis. | Blood 20051001 |
| Temperature-sensitive polymer-conjugated IFN-gamma induces the expression of IDO mRNA and activity by fibroblasts populated in collagen gel (FPCG). | Journal of cellular physiology 20041001 |
| Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. | The Journal of clinical investigation 20040715 |