Home Other Building Blocks 1H-Pyrazolo[3,4-c]pyridine

1H-Pyrazolo[3,4-c]pyridine

CAS No.:
271-47-6
Catalog Number:
AG0032RZ
Molecular Formula:
C6H5N3
Molecular Weight:
119.1240
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
97%
1 week
United States
$73
- +
5g
97%
1 week
United States
$144
- +
10g
97%
1 week
United States
$235
- +
Product Description
Catalog Number:
AG0032RZ
Chemical Name:
1H-Pyrazolo[3,4-c]pyridine
CAS Number:
271-47-6
Molecular Formula:
C6H5N3
Molecular Weight:
119.1240
MDL Number:
MFCD00661308
IUPAC Name:
1H-pyrazolo[3,4-c]pyridine
InChI:
InChI=1S/C6H5N3/c1-2-7-4-6-5(1)3-8-9-6/h1-4H,(H,8,9)
InChI Key:
KNYHISBJRQVMAZ-UHFFFAOYSA-N
SMILES:
c1ncc2c(c1)cn[nH]2
Properties
Complexity:
105  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
119.048g/mol
Formal Charge:
0
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
119.127g/mol
Monoisotopic Mass:
119.048g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
41.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.5  
Literature
Title Journal
Au(I)-catalyzed and iodine-mediated cyclization of enynylpyrazoles to provide pyrazolo[1,5-a]pyridines. Organic & biomolecular chemistry 20120907
Ultrasound assisted one-pot, three-components synthesis of pyrimido[1,2-a]benzimidazoles and pyrazolo[3,4-b]pyridines: A new access via phenylsulfone synthon. Ultrasonics sonochemistry 20120101
Synthesis, X-ray crystal structure and fluorescent spectra of novel pyrazolo[1,5-a]pyrazin-4(5H)-one derivatives. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111015
Phosphodiesterase inhibitors. Part 2: design, synthesis, and structure-activity relationships of dual PDE3/4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory and bronchodilatory activity. Bioorganic & medicinal chemistry letters 20110915
A copper-mediated cyclization reaction of hydrazine with enediynones providing pyrazolo[1,5-a]pyridines. Organic & biomolecular chemistry 20110207
One-step synthesis of diarylpyrazolo[3,4-b]pyridines from isoflavones. Journal of combinatorial chemistry 20100712
Novel pyrazolopyrimidines as highly potent B-Raf inhibitors. Bioorganic & medicinal chemistry letters 20091215
An efficient one-step synthesis of heterobiaryl pyrazolo[3,4-b]pyridines via indole ring opening. Organic letters 20091119
Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors. Journal of medicinal chemistry 20090326
Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model. ChemMedChem 20080601
Synthesis and antiviral activity evaluation of some novel acyclic C-nucleosides. Chemical & pharmaceutical bulletin 20080601
Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems. Journal of medicinal chemistry 20080410
Synthesis, radiofluorination, and in vitro evaluation of pyrazolo[1,5-a]pyridine-based dopamine D4 receptor ligands: discovery of an inverse agonist radioligand for PET. Journal of medicinal chemistry 20080327
Concise routes to pyrazolo[1,5-a]pyridin-3-yl pyridazin-3-ones. Organic & biomolecular chemistry 20080107
Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2. Bioorganic & medicinal chemistry letters 20071115
Rapid hit to lead evaluation of pyrazolo[3,4-d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists. Bioorganic & medicinal chemistry letters 20070801
Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents. Bioorganic & medicinal chemistry letters 20070801
Pyrazolo[1,5-a]pyridine antiherpetics: effects of the C3 substituent on antiviral activity. Bioorganic & medicinal chemistry letters 20070515
Pyrazoloheteroaryls: novel p38alpha MAP kinase inhibiting scaffolds with oral activity. Bioorganic & medicinal chemistry letters 20060115
New pyrazolo[3,4-b]pyridones as selective A(1) adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies. Organic & biomolecular chemistry 20050621
Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors. Journal of medicinal chemistry 20030327
Synthesis and biological evaluation of some acyclic 4,6-disubstituted 1H-pyrazolo[3,4-d]pyrimidine nucleosides. Nucleosides, nucleotides & nucleic acids 20030101
Properties