1H-Pyrazolo[3,4-c]pyridine
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Au(I)-catalyzed and iodine-mediated cyclization of enynylpyrazoles to provide pyrazolo[1,5-a]pyridines. | Organic & biomolecular chemistry 20120907 |
Ultrasound assisted one-pot, three-components synthesis of pyrimido[1,2-a]benzimidazoles and pyrazolo[3,4-b]pyridines: A new access via phenylsulfone synthon. | Ultrasonics sonochemistry 20120101 |
Synthesis, X-ray crystal structure and fluorescent spectra of novel pyrazolo[1,5-a]pyrazin-4(5H)-one derivatives. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20111015 |
Phosphodiesterase inhibitors. Part 2: design, synthesis, and structure-activity relationships of dual PDE3/4-inhibitory pyrazolo[1,5-a]pyridines with anti-inflammatory and bronchodilatory activity. | Bioorganic & medicinal chemistry letters 20110915 |
A copper-mediated cyclization reaction of hydrazine with enediynones providing pyrazolo[1,5-a]pyridines. | Organic & biomolecular chemistry 20110207 |
One-step synthesis of diarylpyrazolo[3,4-b]pyridines from isoflavones. | Journal of combinatorial chemistry 20100712 |
Novel pyrazolopyrimidines as highly potent B-Raf inhibitors. | Bioorganic & medicinal chemistry letters 20091215 |
An efficient one-step synthesis of heterobiaryl pyrazolo[3,4-b]pyridines via indole ring opening. | Organic letters 20091119 |
Exploiting the pyrazolo[3,4-d]pyrimidin-4-one ring system as a useful template to obtain potent adenosine deaminase inhibitors. | Journal of medicinal chemistry 20090326 |
Substituted pyrazolo[3,4-b]pyridines as potent A1 adenosine antagonists: synthesis, biological evaluation, and development of an A1 bovine receptor model. | ChemMedChem 20080601 |
Synthesis and antiviral activity evaluation of some novel acyclic C-nucleosides. | Chemical & pharmaceutical bulletin 20080601 |
Design, synthesis, and biological evaluation of AT1 angiotensin II receptor antagonists based on the pyrazolo[3,4-b]pyridine and related heteroaromatic bicyclic systems. | Journal of medicinal chemistry 20080410 |
Synthesis, radiofluorination, and in vitro evaluation of pyrazolo[1,5-a]pyridine-based dopamine D4 receptor ligands: discovery of an inverse agonist radioligand for PET. | Journal of medicinal chemistry 20080327 |
Concise routes to pyrazolo[1,5-a]pyridin-3-yl pyridazin-3-ones. | Organic & biomolecular chemistry 20080107 |
Pyrazolo[1,5-a]pyrimidines as orally available inhibitors of cyclin-dependent kinase 2. | Bioorganic & medicinal chemistry letters 20071115 |
Rapid hit to lead evaluation of pyrazolo[3,4-d]pyrimidin-4-one as selective and orally bioavailable mGluR1 antagonists. | Bioorganic & medicinal chemistry letters 20070801 |
Synthesis and evaluation of pyrazolo[3,4-b]pyridine CDK1 inhibitors as anti-tumor agents. | Bioorganic & medicinal chemistry letters 20070801 |
Pyrazolo[1,5-a]pyridine antiherpetics: effects of the C3 substituent on antiviral activity. | Bioorganic & medicinal chemistry letters 20070515 |
Pyrazoloheteroaryls: novel p38alpha MAP kinase inhibiting scaffolds with oral activity. | Bioorganic & medicinal chemistry letters 20060115 |
New pyrazolo[3,4-b]pyridones as selective A(1) adenosine receptor antagonists: synthesis, biological evaluation and molecular modelling studies. | Organic & biomolecular chemistry 20050621 |
Design, synthesis, and pharmacological profile of novel fused pyrazolo[4,3-d]pyridine and pyrazolo[3,4-b][1,8]naphthyridine isosteres: a new class of potent and selective acetylcholinesterase inhibitors. | Journal of medicinal chemistry 20030327 |
Synthesis and biological evaluation of some acyclic 4,6-disubstituted 1H-pyrazolo[3,4-d]pyrimidine nucleosides. | Nucleosides, nucleotides & nucleic acids 20030101 |